locus-tag	class	description
H0H24_RS00110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0H24_RS00125	COG4215	(ABC) transporter
H0H24_RS00130	COG4160	amino acid transport
H0H24_RS00135	COG4598	ABC transporter
H0H24_RS00145	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0H24_RS00150	COG0826	peptidase U32
H0H24_RS00155	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0H24_RS00160	COG0384	phenazine biosynthesis protein PhzF
H0H24_RS00170	COG1720	tRNA m6t6A37 methyltransferase activity
H0H24_RS00180	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H0H24_RS00195	COG0642	Histidine kinase
H0H24_RS00205	COG0494	nUDIX hydrolase
H0H24_RS00215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H0H24_RS00220	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H0H24_RS00225	COG3139	Protein of unknown function (DUF1315)
H0H24_RS00230	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H0H24_RS00235	COG1301	dicarboxylic acid transport
H0H24_RS00240	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS00245	COG2819	hydrolase of the alpha beta superfamily
H0H24_RS00255	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H0H24_RS00265	COG2195	Cleaves the N-terminal amino acid of tripeptides
H0H24_RS00270	COG1234	tRNA 3'-trailer cleavage
H0H24_RS00300	COG2363	Small membrane protein
H0H24_RS00320	COG0513	Belongs to the DEAD box helicase family
H0H24_RS00330	COG0778	Nitroreductase
H0H24_RS00360	COG1286	toxin biosynthetic process
H0H24_RS00385	COG4783	chaperone-mediated protein folding
H0H24_RS00390	COG1610	YqeY-like protein
H0H24_RS00420	COG0515	serine threonine protein kinase
H0H24_RS00420	COG2815	serine threonine protein kinase
H0H24_RS00445	COG2831	hemolysin activation secretion protein
H0H24_RS00550	COG3111	PFAM Bacterial OB fold (BOF) protein
H0H24_RS00575	COG3243	poly(R)-hydroxyalkanoic acid synthase
H0H24_RS00580	COG0786	glutamate:sodium symporter activity
H0H24_RS00590	COG2186	Transcriptional regulator
H0H24_RS00640	COG0477	Major facilitator Superfamily
H0H24_RS00645	COG1051	belongs to the nudix hydrolase family
H0H24_RS00675	COG2995	paraquat-inducible protein a
H0H24_RS00680	COG3008	intermembrane lipid transfer
H0H24_RS00680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H0H24_RS00690	COG1794	racemase activity, acting on amino acids and derivatives
H0H24_RS00725	COG1301	dicarboxylic acid transport
H0H24_RS00735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0H24_RS00740	COG2011	ABC-type metal ion transport system permease component
H0H24_RS00745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0H24_RS00750	COG1464	Belongs to the NlpA lipoprotein family
H0H24_RS00755	COG0151	Belongs to the GarS family
H0H24_RS00760	COG0138	bifunctional purine biosynthesis protein purh
H0H24_RS00765	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H0H24_RS00795	COG2308	Evidence 4 Homologs of previously reported genes of
H0H24_RS00805	COG1305	Transglutaminase-like
H0H24_RS00815	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H0H24_RS00820	COG0305	Participates in initiation and elongation during chromosome replication
H0H24_RS00845	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H0H24_RS00855	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H0H24_RS00860	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H0H24_RS00885	COG1649	PFAM Uncharacterised BCR, COG1649
H0H24_RS00885	COG0726	polysaccharide deacetylase
H0H24_RS00890	COG1215	transferase activity, transferring glycosyl groups
H0H24_RS00895	COG3658	cytochrome
H0H24_RS00905	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0H24_RS00920	COG0583	DNA-binding transcription factor activity
H0H24_RS00950	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS00955	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0H24_RS00960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0H24_RS00975	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H0H24_RS00985	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H0H24_RS00990	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H0H24_RS01000	COG2205	protein histidine kinase activity
H0H24_RS01005	COG0745	RESPONSE REGULATOR receiver
H0H24_RS01010	COG0174	glutamine synthetase
H0H24_RS01030	COG0729	surface antigen
H0H24_RS01055	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H0H24_RS01060	COG2814	Major facilitator Superfamily
H0H24_RS01075	COG0583	DNA-binding transcription factor activity
H0H24_RS01090	COG1187	pseudouridine synthase activity
H0H24_RS01110	COG0802	atpase or kinase
H0H24_RS01115	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H0H24_RS01125	COG1923	regulation of RNA biosynthetic process
H0H24_RS01130	COG0697	spore germination
H0H24_RS01145	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0H24_RS01155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0H24_RS01160	COG0519	Catalyzes the synthesis of GMP from XMP
H0H24_RS01160	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0H24_RS01165	COG4302	ethanolamine ammonia-lyase activity
H0H24_RS01170	COG4303	Ethanolamine ammonia lyase large subunit
H0H24_RS01175	COG0531	amino acid
H0H24_RS01195	COG1454	alcohol dehydrogenase
H0H24_RS01200	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0H24_RS01210	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H0H24_RS01230	COG0308	aminopeptidase N
H0H24_RS01270	COG1605	Chorismate mutase
H0H24_RS01285	COG1309	transcriptional regulator
H0H24_RS01295	COG0668	transmembrane transport
H0H24_RS01325	COG4773	Receptor
H0H24_RS01345	COG0488	(ABC) transporter
H0H24_RS01350	COG0589	response to stress
H0H24_RS01375	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H0H24_RS01390	COG1522	sequence-specific DNA binding
H0H24_RS01420	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H0H24_RS01425	COG0583	DNA-binding transcription factor activity
H0H24_RS01435	COG0183	Belongs to the thiolase family
H0H24_RS01445	COG2030	dehydratase
H0H24_RS01450	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0H24_RS01465	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H0H24_RS01475	COG0824	Thioesterase
H0H24_RS01480	COG1454	alcohol dehydrogenase
H0H24_RS01490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H0H24_RS01510	COG0069	glutamate synthase activity
H0H24_RS01560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0H24_RS01655	COG1484	DNA-dependent DNA replication
H0H24_RS01850	COG2026	Addiction module toxin, RelE StbE family
H0H24_RS01890	COG0592	DNA-directed DNA polymerase activity
H0H24_RS01935	COG2963	transposase activity
H0H24_RS02000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0H24_RS02020	COG2814	Major facilitator Superfamily
H0H24_RS02035	COG0511	ligase activity, forming carbon-carbon bonds
H0H24_RS02050	COG1116	anion transmembrane transporter activity
H0H24_RS02050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0H24_RS02055	COG0745	RESPONSE REGULATOR receiver
H0H24_RS02065	COG2146	nitrite reductase [NAD(P)H] activity
H0H24_RS02065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0H24_RS02070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0H24_RS02075	COG0243	molybdopterin cofactor binding
H0H24_RS02085	COG0243	molybdopterin cofactor binding
H0H24_RS02090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H0H24_RS02105	COG0315	cyclic pyranopterin monophosphate synthase activity
H0H24_RS02105	COG0521	Mo-molybdopterin cofactor biosynthetic process
H0H24_RS02110	COG0303	'Molybdopterin
H0H24_RS02120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0H24_RS02125	COG0697	spore germination
H0H24_RS02145	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H0H24_RS02150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0H24_RS02205	COG2204	response regulator
H0H24_RS02210	COG3852	Histidine kinase
H0H24_RS02235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H0H24_RS02240	COG0575	Belongs to the CDS family
H0H24_RS02275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0H24_RS02290	COG2137	regulation of response to DNA damage stimulus
H0H24_RS02300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H0H24_RS02305	COG1011	Hydrolase
H0H24_RS02330	COG1522	sequence-specific DNA binding
H0H24_RS02340	COG1113	amino acid transport
H0H24_RS02355	COG0659	secondary active sulfate transmembrane transporter activity
H0H24_RS02360	COG2135	peptidase activity
H0H24_RS02380	COG5001	Diguanylate cyclase
H0H24_RS02380	COG3300	MHYT domain
H0H24_RS02425	COG1105	Belongs to the carbohydrate kinase PfkB family
H0H24_RS02430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0H24_RS02430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H0H24_RS02460	COG0024	Methionine aminopeptidase
H0H24_RS02465	COG0583	DNA-binding transcription factor activity
H0H24_RS02475	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H0H24_RS02480	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H0H24_RS02485	COG0517	IMP dehydrogenase activity
H0H24_RS02485	COG0516	GMP reductase activity
H0H24_RS02510	COG0552	protein localization to endoplasmic reticulum
H0H24_RS02520	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H0H24_RS02530	COG4890	Cyd operon protein YbgT
H0H24_RS02535	COG1294	oxidase, subunit
H0H24_RS02555	COG1585	Membrane protein implicated in regulation of membrane protease activity
H0H24_RS02565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H0H24_RS02570	COG4774	siderophore transport
H0H24_RS02585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H0H24_RS02590	COG0569	domain protein
H0H24_RS02595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0H24_RS02625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H0H24_RS02630	COG0542	response to heat
H0H24_RS02655	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0H24_RS02655	COG1902	pentaerythritol trinitrate reductase activity
H0H24_RS02700	COG2323	membrane
H0H24_RS02705	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H0H24_RS02715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0H24_RS02720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0H24_RS02725	COG0183	Belongs to the thiolase family
H0H24_RS02730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H0H24_RS02735	COG0596	Alpha beta hydrolase
H0H24_RS02740	COG2271	Major facilitator Superfamily
H0H24_RS02750	COG3485	protocatechuate 3,4-dioxygenase
H0H24_RS02755	COG3485	protocatechuate 3,4-dioxygenase
H0H24_RS02760	COG0710	3-dehydroquinate dehydratase activity
H0H24_RS02765	COG3420	alginic acid biosynthetic process
H0H24_RS02770	COG3659	wide pore channel activity
H0H24_RS02775	COG4993	Dehydrogenase
H0H24_RS02785	COG2391	methyltransferase activity
H0H24_RS02800	COG1414	Transcriptional regulator
H0H24_RS02805	COG0583	DNA-binding transcription factor activity
H0H24_RS02810	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS02835	COG2814	Major facilitator Superfamily
H0H24_RS02865	COG4638	Rieske (2fe-2S)
H0H24_RS02875	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS02885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0H24_RS02895	COG3733	amine oxidase
H0H24_RS02905	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS02915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0H24_RS02925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0H24_RS02930	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0H24_RS02940	COG4829	muconolactone delta-isomerase
H0H24_RS02945	COG4948	Mandelate Racemase Muconate Lactonizing
H0H24_RS02950	COG0583	DNA-binding transcription factor activity
H0H24_RS02970	COG2186	Transcriptional regulator
H0H24_RS03005	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0H24_RS03005	COG1902	pentaerythritol trinitrate reductase activity
H0H24_RS03045	COG1309	transcriptional regulator
H0H24_RS03055	COG1335	isochorismatase
H0H24_RS03060	COG0583	DNA-binding transcription factor activity
H0H24_RS03070	COG0475	glutathione-regulated potassium exporter activity
H0H24_RS03070	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0H24_RS03080	COG1473	amidohydrolase
H0H24_RS03095	COG4191	Histidine kinase
H0H24_RS03130	COG2188	Transcriptional regulator
H0H24_RS03145	COG0583	DNA-binding transcription factor activity
H0H24_RS03170	COG1566	PFAM secretion protein HlyD family protein
H0H24_RS03185	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS03190	COG0129	dihydroxy-acid dehydratase activity
H0H24_RS03205	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0H24_RS03215	COG2084	Dehydrogenase
H0H24_RS03220	COG2207	Transcriptional regulator
H0H24_RS03235	COG1064	alcohol dehydrogenase
H0H24_RS03245	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0H24_RS03250	COG1120	ATPase activity
H0H24_RS03270	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0H24_RS03320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H0H24_RS03355	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0H24_RS03405	COG0583	DNA-binding transcription factor activity
H0H24_RS03415	COG1414	Transcriptional regulator
H0H24_RS03420	COG2851	Citrate transporter
H0H24_RS03425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0H24_RS03430	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0H24_RS03435	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS03450	COG2207	Transcriptional regulator
H0H24_RS03460	COG2205	protein histidine kinase activity
H0H24_RS03465	COG0745	RESPONSE REGULATOR receiver
H0H24_RS03475	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0H24_RS03490	COG3539	Fimbrial protein
H0H24_RS03515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H0H24_RS03525	COG0753	catalase activity
H0H24_RS03540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0H24_RS03605	COG1535	isochorismatase
H0H24_RS03605	COG3433	isochorismatase activity
H0H24_RS03610	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS03615	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H0H24_RS03620	COG4149	molybdate abc transporter
H0H24_RS03625	COG0725	ABC transporter, periplasmic molybdate-binding protein
H0H24_RS03645	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0H24_RS03645	COG0543	2 iron, 2 sulfur cluster binding
H0H24_RS03660	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0H24_RS03670	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS03690	COG2963	transposase activity
H0H24_RS03705	COG2207	Transcriptional regulator
H0H24_RS03710	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS03715	COG2610	gluconate transmembrane transporter activity
H0H24_RS03725	COG1309	transcriptional regulator
H0H24_RS03740	COG0583	DNA-binding transcription factor activity
H0H24_RS03755	COG2031	fatty acid transporter
H0H24_RS03760	COG0183	Belongs to the thiolase family
H0H24_RS03765	COG0583	DNA-binding transcription factor activity
H0H24_RS03770	COG0583	DNA-binding transcription factor activity
H0H24_RS03785	COG1027	Aspartate ammonia-lyase
H0H24_RS03795	COG0477	Major facilitator Superfamily
H0H24_RS03820	COG4521	taurine ABC transporter
H0H24_RS03835	COG2188	Transcriptional regulator
H0H24_RS03845	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H0H24_RS03850	COG1733	regulation of RNA biosynthetic process
H0H24_RS03855	COG3708	Transcriptional regulator
H0H24_RS03855	COG2207	Transcriptional regulator
H0H24_RS03870	COG0730	response to heat
H0H24_RS03880	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0H24_RS03880	COG3453	Protein conserved in bacteria
H0H24_RS03890	COG3781	membrane
H0H24_RS03895	COG1063	alcohol dehydrogenase
H0H24_RS03905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0H24_RS03910	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0H24_RS03915	COG0022	dehydrogenase e1 component
H0H24_RS03920	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H0H24_RS03925	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0H24_RS03940	COG3706	GGDEF domain
H0H24_RS03955	COG0133	tryptophan synthase activity
H0H24_RS03965	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0H24_RS04000	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H0H24_RS04025	COG2226	methyltransferase
H0H24_RS04080	COG0842	Transport permease protein
H0H24_RS04085	COG0842	Transport permease protein
H0H24_RS04105	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H0H24_RS04110	COG4773	Receptor
H0H24_RS04130	COG0730	response to heat
H0H24_RS04135	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H0H24_RS04155	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H0H24_RS04170	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0H24_RS04200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0H24_RS04210	COG4264	IucA IucC family
H0H24_RS04235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H0H24_RS04250	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS04255	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS04260	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H0H24_RS04265	COG2207	Transcriptional regulator
H0H24_RS04270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0H24_RS04275	COG0776	regulation of translation
H0H24_RS04300	COG0822	iron-sulfur transferase activity
H0H24_RS04305	COG0316	Belongs to the HesB IscA family
H0H24_RS04335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H0H24_RS04355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H0H24_RS04360	COG0702	epimerase
H0H24_RS04395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H0H24_RS04405	COG0339	signal peptide processing
H0H24_RS04455	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H0H24_RS04460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H0H24_RS04490	COG0776	regulation of translation
H0H24_RS04555	COG0084	hydrolase, TatD family'
H0H24_RS04575	COG1663	tetraacyldisaccharide 4'-kinase activity
H0H24_RS04580	COG1132	(ABC) transporter
H0H24_RS04590	COG0811	peptide transport
H0H24_RS04595	COG1475	DNA binding
H0H24_RS04600	COG1192	Involved in chromosome partitioning
H0H24_RS04610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H0H24_RS04625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H0H24_RS04630	COG0191	fructose-bisphosphate aldolase activity
H0H24_RS04650	COG0424	maF-like protein
H0H24_RS04655	COG2850	peptidyl-arginine hydroxylation
H0H24_RS04665	COG0640	Transcriptional regulator
H0H24_RS04675	COG3619	membrane
H0H24_RS04680	COG3122	Protein conserved in bacteria
H0H24_RS04685	COG1132	(ABC) transporter
H0H24_RS04705	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H0H24_RS04725	COG2963	transposase activity
H0H24_RS04730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0H24_RS04740	COG0506	proline dehydrogenase activity
H0H24_RS04740	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0H24_RS04740	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H0H24_RS04745	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H0H24_RS04760	COG3698	Phosphodiester glycosidase
H0H24_RS04770	COG2353	YceI-like domain
H0H24_RS04780	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H0H24_RS04825	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H0H24_RS04825	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H0H24_RS04850	COG3539	Fimbrial protein
H0H24_RS04855	COG3121	Chaperone
H0H24_RS04880	COG0697	spore germination
H0H24_RS04890	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0H24_RS04900	COG0583	DNA-binding transcription factor activity
H0H24_RS04920	COG1309	transcriptional regulator
H0H24_RS04935	COG1522	sequence-specific DNA binding
H0H24_RS04945	COG1126	abc transporter atp-binding protein
H0H24_RS04950	COG0765	amino acid transport
H0H24_RS04955	COG0765	amino acid transport
H0H24_RS04985	COG1464	Belongs to the NlpA lipoprotein family
H0H24_RS04995	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H0H24_RS05000	COG2011	ABC-type metal ion transport system permease component
H0H24_RS05005	COG0012	GTP binding
H0H24_RS05030	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0H24_RS05070	COG0386	Belongs to the glutathione peroxidase family
H0H24_RS05080	COG0436	Aminotransferase
H0H24_RS05120	COG3634	alkyl hydroperoxide reductase activity
H0H24_RS05135	COG0583	DNA-binding transcription factor activity
H0H24_RS05140	COG0798	PFAM Bile acid sodium symporter
H0H24_RS05145	COG0640	Transcriptional regulator
H0H24_RS05160	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H0H24_RS05170	COG0583	DNA-binding transcription factor activity
H0H24_RS05180	COG1953	Uracil, thiamine, allantoin
H0H24_RS05190	COG2175	clavaminate synthase activity
H0H24_RS05195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0H24_RS05200	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H0H24_RS05205	COG4521	taurine ABC transporter
H0H24_RS05215	COG0477	Major facilitator Superfamily
H0H24_RS05235	COG1271	oxidase subunit
H0H24_RS05240	COG1294	oxidase, subunit
H0H24_RS05250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0H24_RS05270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H0H24_RS05290	COG3052	prosthetic group binding
H0H24_RS05295	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H0H24_RS05305	COG0583	DNA-binding transcription factor activity
H0H24_RS05315	COG2814	Major facilitator Superfamily
H0H24_RS05335	COG1346	cytolysis
H0H24_RS05345	COG0583	DNA-binding transcription factor activity
H0H24_RS05350	COG0625	glutathione transferase activity
H0H24_RS05355	COG0625	glutathione transferase activity
H0H24_RS05360	COG0583	DNA-binding transcription factor activity
H0H24_RS05375	COG1045	serine acetyltransferase
H0H24_RS05385	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H0H24_RS05390	COG1280	lysine exporter protein (LysE YggA)
H0H24_RS05405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0H24_RS05410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0H24_RS05415	COG1126	abc transporter atp-binding protein
H0H24_RS05420	COG0765	amino acid transport
H0H24_RS05425	COG0765	amino acid transport
H0H24_RS05445	COG0784	Response regulator, receiver
H0H24_RS05445	COG2205	protein histidine kinase activity
H0H24_RS05465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H0H24_RS05485	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS05535	COG0583	DNA-binding transcription factor activity
H0H24_RS05555	COG0318	PFAM AMP-dependent synthetase and ligase
H0H24_RS05560	COG1309	transcriptional regulator
H0H24_RS05565	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS05570	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0H24_RS05575	COG1024	Enoyl-CoA hydratase
H0H24_RS05580	COG4770	biotin carboxylase activity
H0H24_RS05590	COG0583	DNA-binding transcription factor activity
H0H24_RS05605	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS05615	COG2814	Major facilitator Superfamily
H0H24_RS05625	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H0H24_RS05630	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H0H24_RS05635	COG2814	Major facilitator Superfamily
H0H24_RS05640	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS05645	COG1024	Enoyl-CoA hydratase
H0H24_RS05650	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS05655	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0H24_RS05660	COG0183	Belongs to the thiolase family
H0H24_RS05670	COG2814	Major facilitator Superfamily
H0H24_RS05680	COG1024	Enoyl-CoA hydratase
H0H24_RS05690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0H24_RS05695	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS05700	COG2814	Major facilitator Superfamily
H0H24_RS05705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H0H24_RS05710	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H0H24_RS05725	COG3842	ATPase activity
H0H24_RS05730	COG1840	ABC-type Fe3 transport system, periplasmic component
H0H24_RS05740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0H24_RS05745	COG1414	Transcriptional regulator
H0H24_RS05755	COG0583	DNA-binding transcription factor activity
H0H24_RS05760	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H0H24_RS05765	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS05775	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H0H24_RS05790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0H24_RS05795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0H24_RS05800	COG2267	carboxylic ester hydrolase activity
H0H24_RS05820	COG3038	cytochrome b561
H0H24_RS05825	COG0753	catalase activity
H0H24_RS05850	COG2050	protein possibly involved in aromatic compounds catabolism
H0H24_RS05860	COG3327	negative regulation of DNA-templated transcription, initiation
H0H24_RS05865	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H0H24_RS05870	COG0183	Belongs to the thiolase family
H0H24_RS05875	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0H24_RS05880	COG1024	Enoyl-CoA hydratase
H0H24_RS05885	COG1024	Enoyl-CoA hydratase
H0H24_RS05890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0H24_RS05895	COG2151	metal-sulfur cluster biosynthetic enzyme
H0H24_RS05900	COG3396	Phenylacetate-CoA oxygenase
H0H24_RS05905	COG3460	Phenylacetate-CoA oxygenase
H0H24_RS05910	COG3396	Phenylacetate-CoA oxygenase
H0H24_RS05915	COG2030	dehydratase
H0H24_RS05915	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS05920	COG1760	l-serine dehydratase
H0H24_RS05925	COG0531	amino acid
H0H24_RS05930	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS05955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0H24_RS05975	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0H24_RS05985	COG0789	Transcriptional regulator
H0H24_RS05995	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H0H24_RS06010	COG2807	transmembrane transport
H0H24_RS06015	COG0590	tRNA wobble adenosine to inosine editing
H0H24_RS06140	COG1116	anion transmembrane transporter activity
H0H24_RS06145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H0H24_RS06155	COG0864	Transcriptional regulator
H0H24_RS06170	COG1733	regulation of RNA biosynthetic process
H0H24_RS06175	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0H24_RS06180	COG0439	Biotin carboxylase
H0H24_RS06195	COG1063	alcohol dehydrogenase
H0H24_RS06220	COG3210	domain, Protein
H0H24_RS06225	COG2831	hemolysin activation secretion protein
H0H24_RS06230	COG0038	chloride channel
H0H24_RS06235	COG4770	biotin carboxylase activity
H0H24_RS06255	COG1914	H( )-stimulated, divalent metal cation uptake system
H0H24_RS06260	COG0583	DNA-binding transcription factor activity
H0H24_RS06295	COG1250	3-hydroxyacyl-CoA dehydrogenase
H0H24_RS06315	COG2814	Major facilitator Superfamily
H0H24_RS06325	COG1560	Kdo2-lipid A biosynthetic process
H0H24_RS06340	COG1522	sequence-specific DNA binding
H0H24_RS06355	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H0H24_RS06365	COG4122	O-methyltransferase activity
H0H24_RS06395	COG1538	Outer membrane efflux protein
H0H24_RS06400	COG1137	ATPase activity
H0H24_RS06405	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H0H24_RS06415	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H0H24_RS06455	COG2814	Major facilitator Superfamily
H0H24_RS06490	COG1278	Cold shock
H0H24_RS06495	COG1280	lysine exporter protein (LysE YggA)
H0H24_RS06525	COG1570	exodeoxyribonuclease VII activity
H0H24_RS06575	COG0583	DNA-binding transcription factor activity
H0H24_RS06580	COG4638	Rieske (2fe-2S)
H0H24_RS06585	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H0H24_RS06590	COG0633	Ferredoxin
H0H24_RS06590	COG0543	2 iron, 2 sulfur cluster binding
H0H24_RS06595	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS06600	COG3135	benzoate transporter
H0H24_RS06605	COG2814	Major facilitator Superfamily
H0H24_RS06620	COG1643	Atp-dependent helicase
H0H24_RS06625	COG0450	alkyl hydroperoxide reductase
H0H24_RS06635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H0H24_RS06645	COG3634	alkyl hydroperoxide reductase activity
H0H24_RS06665	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H0H24_RS06670	COG0625	glutathione transferase activity
H0H24_RS06680	COG2885	chlorophyll binding
H0H24_RS06715	COG0542	response to heat
H0H24_RS06730	COG1765	OsmC-like protein
H0H24_RS06745	COG0667	Aldo Keto reductase
H0H24_RS06760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H0H24_RS06775	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H0H24_RS06785	COG0527	aspartate kinase activity
H0H24_RS06795	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H0H24_RS06805	COG3038	cytochrome b561
H0H24_RS06810	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H0H24_RS06815	COG2252	PERMEase
H0H24_RS06825	COG2072	flavoprotein involved in K transport
H0H24_RS06840	COG1741	Belongs to the pirin family
H0H24_RS06845	COG1309	transcriptional regulator
H0H24_RS06855	COG0300	oxidoreductase activity
H0H24_RS06860	COG2072	flavoprotein involved in K transport
H0H24_RS06865	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H0H24_RS06910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0H24_RS06925	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0H24_RS06940	COG2814	Major facilitator Superfamily
H0H24_RS06945	COG1024	Enoyl-CoA hydratase
H0H24_RS06950	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS06960	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS06985	COG2186	Transcriptional regulator
H0H24_RS06990	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS07000	COG4948	Mandelate Racemase Muconate Lactonizing
H0H24_RS07005	COG2271	Major facilitator Superfamily
H0H24_RS07010	COG2721	sulfolactate sulfo-lyase activity
H0H24_RS07015	COG0697	spore germination
H0H24_RS07030	COG1113	amino acid transport
H0H24_RS07050	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS07070	COG0531	amino acid
H0H24_RS07080	COG1113	amino acid transport
H0H24_RS07125	COG4269	membrane
H0H24_RS07140	COG1902	pentaerythritol trinitrate reductase activity
H0H24_RS07140	COG0446	pyridine nucleotide-disulphide oxidoreductase
H0H24_RS07150	COG5001	Diguanylate cyclase
H0H24_RS07150	COG3706	GGDEF domain
H0H24_RS07150	COG2203	Gaf domain
H0H24_RS07150	COG4251	negative regulation of phosphorylation
H0H24_RS07160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0H24_RS07180	COG4172	Belongs to the ABC transporter superfamily
H0H24_RS07185	COG4239	(ABC) transporter, permease
H0H24_RS07190	COG4174	ABC transporter (Permease)
H0H24_RS07200	COG0741	lytic transglycosylase activity
H0H24_RS07200	COG1388	LysM domain
H0H24_RS07200	COG0741	lytic transglycosylase activity
H0H24_RS07200	COG1388	LysM domain
H0H24_RS07205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H0H24_RS07245	COG0583	DNA-binding transcription factor activity
H0H24_RS07250	COG1279	arginine transmembrane transporter activity
H0H24_RS07270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0H24_RS07275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0H24_RS07280	COG0006	proline dipeptidase activity
H0H24_RS07315	COG2194	sulfuric ester hydrolase activity
H0H24_RS07650	COG0512	Glutamine amidotransferase of anthranilate synthase
H0H24_RS07655	COG0308	aminopeptidase N
H0H24_RS07695	COG0302	gtp cyclohydrolase
H0H24_RS07720	COG3739	integral membrane protein
H0H24_RS07740	COG2977	Belongs to the P-Pant transferase superfamily
H0H24_RS07745	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H0H24_RS07750	COG1132	(ABC) transporter
H0H24_RS07755	COG1132	(ABC) transporter
H0H24_RS07765	COG1535	isochorismatase
H0H24_RS07765	COG3433	isochorismatase activity
H0H24_RS07770	COG1021	2,3-dihydroxybenzoate-AMP ligase
H0H24_RS07775	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0H24_RS07785	COG4774	siderophore transport
H0H24_RS07790	COG4607	ABC-type enterochelin transport system periplasmic component
H0H24_RS07795	COG4604	ABC transporter, ATP-binding protein
H0H24_RS07800	COG4605	iron ion homeostasis
H0H24_RS07805	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H0H24_RS07810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0H24_RS07825	COG2964	Protein conserved in bacteria
H0H24_RS07835	COG1741	Belongs to the pirin family
H0H24_RS07850	COG1309	transcriptional regulator
H0H24_RS07885	COG4948	Mandelate Racemase Muconate Lactonizing
H0H24_RS07890	COG2814	Major facilitator Superfamily
H0H24_RS07925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H0H24_RS07925	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H0H24_RS07930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0H24_RS07935	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS07950	COG0477	Major facilitator Superfamily
H0H24_RS07955	COG0006	proline dipeptidase activity
H0H24_RS07960	COG1902	pentaerythritol trinitrate reductase activity
H0H24_RS07965	COG0583	DNA-binding transcription factor activity
H0H24_RS07975	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H0H24_RS07985	COG0596	Alpha beta hydrolase
H0H24_RS08000	COG0583	DNA-binding transcription factor activity
H0H24_RS08005	COG1335	isochorismatase
H0H24_RS08045	COG2879	small protein
H0H24_RS08050	COG1966	Carbon starvation protein
H0H24_RS08070	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H0H24_RS08095	COG1067	ATP-dependent peptidase activity
H0H24_RS08100	COG0583	DNA-binding transcription factor activity
H0H24_RS08125	COG1686	Belongs to the peptidase S11 family
H0H24_RS08130	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H0H24_RS08165	COG0616	signal peptide processing
H0H24_RS08170	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H0H24_RS08180	COG0573	inorganic phosphate transmembrane transporter activity
H0H24_RS08185	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H0H24_RS08190	COG1113	amino acid transport
H0H24_RS08200	COG1522	sequence-specific DNA binding
H0H24_RS08210	COG0076	glutamate decarboxylase activity
H0H24_RS08215	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0H24_RS08230	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0H24_RS08240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0H24_RS08275	COG0352	thiamine-phosphate diphosphorylase activity
H0H24_RS08300	COG0612	Peptidase, M16
H0H24_RS08310	COG1823	symporter activity
H0H24_RS08315	COG0583	DNA-binding transcription factor activity
H0H24_RS08320	COG0477	Major facilitator Superfamily
H0H24_RS08345	COG1187	pseudouridine synthase activity
H0H24_RS08360	COG1686	Belongs to the peptidase S11 family
H0H24_RS08365	COG1252	NADH dehydrogenase
H0H24_RS08375	COG0415	Belongs to the DNA photolyase family
H0H24_RS08390	COG1215	transferase activity, transferring glycosyl groups
H0H24_RS08420	COG2070	2-Nitropropane dioxygenase
H0H24_RS08475	COG0556	nucleotide-excision repair
H0H24_RS08495	COG0436	Aminotransferase
H0H24_RS08505	COG0443	Heat shock 70 kDa protein
H0H24_RS08535	COG4221	oxidoreductase activity
H0H24_RS08545	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H0H24_RS08550	COG1381	Involved in DNA repair and RecF pathway recombination
H0H24_RS08560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H0H24_RS08575	COG0681	Belongs to the peptidase S26 family
H0H24_RS08590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0H24_RS08610	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H0H24_RS08615	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H0H24_RS08620	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H0H24_RS08630	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H0H24_RS08635	COG4208	sulfate ABC transporter
H0H24_RS08640	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H0H24_RS08645	COG0583	DNA-binding transcription factor activity
H0H24_RS08650	COG4625	pathogenesis
H0H24_RS08665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H0H24_RS08680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H0H24_RS08690	COG1051	belongs to the nudix hydrolase family
H0H24_RS08690	COG1056	cytidyltransferase-related domain
H0H24_RS08695	COG1024	Enoyl-CoA hydratase
H0H24_RS08705	COG2814	Major facilitator Superfamily
H0H24_RS08710	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H0H24_RS08710	COG0047	phosphoribosylformylglycinamidine synthase activity
H0H24_RS08730	COG1473	amidohydrolase
H0H24_RS08735	COG0824	Thioesterase
H0H24_RS08755	COG0823	Involved in the tonB-independent uptake of proteins
H0H24_RS08775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0H24_RS08830	COG0628	permease
H0H24_RS08840	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H0H24_RS08845	COG0596	Alpha beta hydrolase
H0H24_RS08850	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H0H24_RS08850	COG0616	signal peptide processing
H0H24_RS08860	COG2333	competence protein COMEC
H0H24_RS08860	COG0658	competence protein
H0H24_RS08865	COG1136	(ABC) transporter
H0H24_RS08870	COG4591	ABC-type transport system involved in lipoprotein release permease component
H0H24_RS08905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0H24_RS08925	COG0463	Glycosyl transferase, family 2
H0H24_RS08955	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H0H24_RS08960	COG1280	lysine exporter protein (LysE YggA)
H0H24_RS08970	COG0019	diaminopimelate decarboxylase activity
H0H24_RS08980	COG1113	amino acid transport
H0H24_RS08995	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H0H24_RS09005	COG3339	Conserved Protein
H0H24_RS09010	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H0H24_RS09015	COG0243	molybdopterin cofactor binding
H0H24_RS09020	COG1929	Belongs to the glycerate kinase type-1 family
H0H24_RS09035	COG0778	Nitroreductase
H0H24_RS09055	COG3811	Belongs to the UPF0386 family
H0H24_RS09080	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H0H24_RS09100	COG0741	lytic transglycosylase activity
H0H24_RS09120	COG0584	glycerophosphoryl diester phosphodiesterase
H0H24_RS09125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0H24_RS09150	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0H24_RS09155	COG1597	lipid kinase activity
H0H24_RS09170	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H0H24_RS09175	COG0477	Major facilitator Superfamily
H0H24_RS09225	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H0H24_RS09230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H0H24_RS09255	COG0505	Belongs to the CarA family
H0H24_RS09275	COG0589	response to stress
H0H24_RS09290	COG2843	Capsule synthesis protein
H0H24_RS09395	COG2321	neutral zinc metallopeptidase
H0H24_RS09400	COG2354	Protein conserved in bacteria
H0H24_RS09420	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0H24_RS09445	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H0H24_RS09450	COG1053	succinate dehydrogenase
H0H24_RS09455	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H0H24_RS09460	COG2009	succinate dehydrogenase
H0H24_RS09500	COG2921	Belongs to the UPF0250 family
H0H24_RS09505	COG0321	lipoyl(octanoyl) transferase activity
H0H24_RS09520	COG0531	amino acid
H0H24_RS09530	COG1733	regulation of RNA biosynthetic process
H0H24_RS09535	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H0H24_RS09540	COG1648	precorrin-2 dehydrogenase activity
H0H24_RS09540	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H0H24_RS09555	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H0H24_RS09585	COG0671	phosphoesterase, PA-phosphatase related
H0H24_RS09590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0H24_RS09600	COG1538	Outer membrane efflux protein
H0H24_RS09605	COG0393	Putative heavy-metal-binding
H0H24_RS09610	COG0393	Putative heavy-metal-binding
H0H24_RS09620	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS09630	COG0525	valine-tRNA ligase activity
H0H24_RS09635	COG2226	methyltransferase
H0H24_RS09650	COG0583	DNA-binding transcription factor activity
H0H24_RS09655	COG0004	ammonium transporteR
H0H24_RS09665	COG0642	Histidine kinase
H0H24_RS09670	COG0745	RESPONSE REGULATOR receiver
H0H24_RS09725	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0H24_RS09740	COG2315	Protein conserved in bacteria
H0H24_RS09745	COG0142	geranyltranstransferase activity
H0H24_RS09750	COG2828	Protein conserved in bacteria
H0H24_RS09755	COG1113	amino acid transport
H0H24_RS09805	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H0H24_RS09815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H0H24_RS09820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H0H24_RS09825	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H0H24_RS09885	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0H24_RS09895	COG1846	Transcriptional regulator
H0H24_RS09900	COG1764	response to oxidative stress
H0H24_RS09940	COG0037	tRNA processing
H0H24_RS09950	COG0248	Ppx GppA phosphatase
H0H24_RS09980	COG0072	phenylalanine-tRNA ligase activity
H0H24_RS10020	COG1238	metal cluster binding
H0H24_RS10025	COG0625	glutathione transferase activity
H0H24_RS10040	COG0318	PFAM AMP-dependent synthetase and ligase
H0H24_RS10045	COG3028	Belongs to the UPF0307 family
H0H24_RS10050	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H0H24_RS10070	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H0H24_RS10075	COG0617	tRNA 3'-terminal CCA addition
H0H24_RS10080	COG1555	photosystem II stabilization
H0H24_RS10085	COG3956	TIGRFAM MazG family protein
H0H24_RS10095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0H24_RS10115	COG0784	Response regulator, receiver
H0H24_RS10115	COG5002	protein histidine kinase activity
H0H24_RS10115	COG2205	protein histidine kinase activity
H0H24_RS10120	COG1024	Enoyl-CoA hydratase
H0H24_RS10125	COG2084	Dehydrogenase
H0H24_RS10130	COG3622	Belongs to the hyi family
H0H24_RS10160	COG0697	spore germination
H0H24_RS10170	COG2814	Major facilitator Superfamily
H0H24_RS10175	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0H24_RS10185	COG0583	DNA-binding transcription factor activity
H0H24_RS10195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H0H24_RS10205	COG0084	hydrolase, TatD family'
H0H24_RS10250	COG0440	acetolactate synthase activity
H0H24_RS10255	COG0028	Belongs to the TPP enzyme family
H0H24_RS10280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0H24_RS10285	COG0577	efflux transmembrane transporter activity
H0H24_RS10285	COG1136	(ABC) transporter
H0H24_RS10290	COG1538	Outer membrane efflux protein
H0H24_RS10305	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H0H24_RS10310	COG1162	GTPase activity
H0H24_RS10320	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H0H24_RS10360	COG1426	Protein conserved in bacteria
H0H24_RS10395	COG0793	Belongs to the peptidase S41A family
H0H24_RS10410	COG2267	carboxylic ester hydrolase activity
H0H24_RS10420	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS10425	COG3265	gluconokinase activity
H0H24_RS10435	COG0800	Aldolase
H0H24_RS10445	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H0H24_RS10450	COG0857	belongs to the CobB CobQ family
H0H24_RS10450	COG0280	phosphate acetyltransferase
H0H24_RS10455	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H0H24_RS10455	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H0H24_RS10475	COG0740	serine-type endopeptidase activity
H0H24_RS10485	COG4774	siderophore transport
H0H24_RS10495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H0H24_RS10505	COG2813	Specifically methylates the guanine in position
H0H24_RS10505	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0H24_RS10605	COG0788	formyltetrahydrofolate deformylase activity
H0H24_RS10630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0H24_RS10630	COG4651	solute:proton antiporter activity
H0H24_RS10650	COG0724	RNA recognition motif
H0H24_RS10655	COG0210	DNA helicase
H0H24_RS10680	COG1733	regulation of RNA biosynthetic process
H0H24_RS10690	COG2900	Belongs to the SlyX family
H0H24_RS10695	COG0488	(ABC) transporter
H0H24_RS10700	COG1280	lysine exporter protein (LysE YggA)
H0H24_RS10705	COG1560	Kdo2-lipid A biosynthetic process
H0H24_RS10715	COG1301	dicarboxylic acid transport
H0H24_RS10770	COG0473	3-isopropylmalate dehydrogenase activity
H0H24_RS10835	COG0583	DNA-binding transcription factor activity
H0H24_RS10845	COG0625	glutathione transferase activity
H0H24_RS10850	COG2378	regulation of single-species biofilm formation
H0H24_RS10855	COG0546	phosphoglycolate phosphatase activity
H0H24_RS10865	COG1530	ribonuclease E activity
H0H24_RS10870	COG0318	PFAM AMP-dependent synthetase and ligase
H0H24_RS10885	COG0583	DNA-binding transcription factor activity
H0H24_RS10890	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS10895	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H0H24_RS10905	COG0534	Mate efflux family protein
H0H24_RS10920	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H0H24_RS11000	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0H24_RS11000	COG0493	'glutamate synthase
H0H24_RS11010	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H0H24_RS11015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H0H24_RS11030	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H0H24_RS11040	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H0H24_RS11040	COG0644	oxidoreductase
H0H24_RS11050	COG0425	Belongs to the sulfur carrier protein TusA family
H0H24_RS11055	COG4535	Mg2 and Co2 transporter CorC
H0H24_RS11065	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0H24_RS11085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H0H24_RS11090	COG0475	glutathione-regulated potassium exporter activity
H0H24_RS11090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H0H24_RS11105	COG0484	heat shock protein binding
H0H24_RS11110	COG0789	Transcriptional regulator
H0H24_RS11115	COG0598	Magnesium transport protein CorA
H0H24_RS11130	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H0H24_RS11135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H0H24_RS11140	COG1074	ATP-dependent DNA helicase activity
H0H24_RS11145	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H0H24_RS11165	COG2226	methyltransferase
H0H24_RS11180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0H24_RS11185	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H0H24_RS11200	COG2111	Na H antiporter
H0H24_RS11200	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0H24_RS11205	COG1006	Multisubunit Na H antiporter MnhC subunit
H0H24_RS11210	COG0651	ATP synthesis coupled electron transport
H0H24_RS11215	COG1863	multisubunit Na H antiporter MnhE subunit
H0H24_RS11220	COG2212	antiporter activity
H0H24_RS11225	COG1320	monovalent cation:proton antiporter activity
H0H24_RS11240	COG0195	Participates in both transcription termination and antitermination
H0H24_RS11290	COG0237	dephospho-CoA kinase activity
H0H24_RS11300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H0H24_RS11315	COG0497	DNA recombination
H0H24_RS11325	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H0H24_RS11355	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0H24_RS11355	COG2169	Transcriptional regulator
H0H24_RS11360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H0H24_RS11410	COG0789	Transcriptional regulator
H0H24_RS11420	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H0H24_RS11435	COG0326	Molecular chaperone. Has ATPase activity
H0H24_RS11450	COG2056	Na+-H+ antiporter family
H0H24_RS11560	COG0546	phosphoglycolate phosphatase activity
H0H24_RS11565	COG1716	ATPase activity
H0H24_RS11610	COG0181	hydroxymethylbilane synthase activity
H0H24_RS11620	COG3275	phosphorelay sensor kinase activity
H0H24_RS11640	COG1538	Outer membrane efflux protein
H0H24_RS11645	COG0697	spore germination
H0H24_RS11670	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H0H24_RS11675	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H0H24_RS11680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H0H24_RS11685	COG0772	Belongs to the SEDS family
H0H24_RS11710	COG4974	Belongs to the 'phage' integrase family
H0H24_RS11715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0H24_RS11725	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H0H24_RS11735	COG2197	response regulator
H0H24_RS11755	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H0H24_RS11760	COG0795	lipopolysaccharide-transporting ATPase activity
H0H24_RS11800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0H24_RS11800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H0H24_RS11810	COG0004	ammonium transporteR
H0H24_RS11815	COG0347	Belongs to the P(II) protein family
H0H24_RS11825	COG0606	chelatase, subunit chli
H0H24_RS11895	COG2132	Multicopper oxidase
H0H24_RS11910	COG2205	protein histidine kinase activity
H0H24_RS11915	COG2217	Heavy metal translocating P-type atpase
H0H24_RS11955	COG0606	chelatase, subunit chli
H0H24_RS11960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0H24_RS11965	COG0235	Class ii aldolase
H0H24_RS11970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0H24_RS11990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H0H24_RS12005	COG0318	PFAM AMP-dependent synthetase and ligase
H0H24_RS12015	COG0477	Major facilitator Superfamily
H0H24_RS12020	COG2860	membrane
H0H24_RS12025	COG3012	SEC-C Motif Domain Protein
H0H24_RS12030	COG1253	flavin adenine dinucleotide binding
H0H24_RS12040	COG0477	Major facilitator Superfamily
H0H24_RS12050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H0H24_RS12085	COG0655	NAD(P)H dehydrogenase (quinone) activity
H0H24_RS12095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H0H24_RS12130	COG1309	transcriptional regulator
H0H24_RS12165	COG0758	DNA mediated transformation
H0H24_RS12175	COG0697	spore germination
H0H24_RS12180	COG1309	transcriptional regulator
H0H24_RS12195	COG0386	Belongs to the glutathione peroxidase family
H0H24_RS12265	COG1121	(ABC) transporter
H0H24_RS12270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H0H24_RS12275	COG1280	lysine exporter protein (LysE YggA)
H0H24_RS12280	COG2837	iron assimilation
H0H24_RS12335	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H0H24_RS12335	COG0519	Catalyzes the synthesis of GMP from XMP
H0H24_RS12340	COG4399	Belongs to the UPF0754 family
H0H24_RS12345	COG2259	Doxx family
H0H24_RS12350	COG0586	Pfam SNARE associated Golgi protein
H0H24_RS12365	COG1192	Involved in chromosome partitioning
H0H24_RS12375	COG0271	Belongs to the BolA IbaG family
H0H24_RS12395	COG1024	Enoyl-CoA hydratase
H0H24_RS12400	COG1024	Enoyl-CoA hydratase
H0H24_RS12405	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS12410	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0H24_RS12430	COG1113	amino acid transport
H0H24_RS12435	COG1113	amino acid transport
H0H24_RS12440	COG0251	oxidation-reduction process
H0H24_RS12480	COG0564	pseudouridine synthase activity
H0H24_RS12550	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H0H24_RS12565	COG1802	Transcriptional regulator
H0H24_RS12575	COG1448	Aminotransferase
H0H24_RS12585	COG0277	FAD linked oxidase domain protein
H0H24_RS12595	COG2186	Transcriptional regulator
H0H24_RS12605	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0H24_RS12610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H0H24_RS12625	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H0H24_RS12630	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H0H24_RS12635	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H0H24_RS12680	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS12685	COG1083	cytidylyl-transferase
H0H24_RS12690	COG0673	inositol 2-dehydrogenase activity
H0H24_RS12695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H0H24_RS12700	COG1045	serine acetyltransferase
H0H24_RS12705	COG2089	acid synthase
H0H24_RS12710	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
H0H24_RS12715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H0H24_RS12725	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H0H24_RS12730	COG1596	polysaccharide export
H0H24_RS12755	COG0728	peptidoglycan biosynthetic process
H0H24_RS12760	COG3023	N-Acetylmuramoyl-L-alanine amidase
H0H24_RS12820	COG0546	phosphoglycolate phosphatase activity
H0H24_RS12825	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS12845	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H0H24_RS12855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H0H24_RS12860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H0H24_RS12865	COG1116	anion transmembrane transporter activity
H0H24_RS12870	COG1309	transcriptional regulator
H0H24_RS12875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H0H24_RS12885	COG0196	riboflavin kinase activity
H0H24_RS12890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H0H24_RS12900	COG1047	Peptidyl-prolyl cis-trans
H0H24_RS12940	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H0H24_RS12945	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H0H24_RS12950	COG0596	Alpha beta hydrolase
H0H24_RS12975	COG0488	(ABC) transporter
H0H24_RS12980	COG0586	Pfam SNARE associated Golgi protein
H0H24_RS12990	COG0187	DNA topoisomerase II activity
H0H24_RS13000	COG0592	DNA-directed DNA polymerase activity
H0H24_RS13030	COG0706	membrane insertase activity
H0H24_RS13045	COG1230	cation diffusion facilitator family transporter
H0H24_RS13050	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0H24_RS13065	COG0402	S-adenosylhomocysteine deaminase activity
H0H24_RS13075	COG0754	glutathionylspermidine amidase activity
H0H24_RS13085	COG0861	Integral membrane protein TerC family
H0H24_RS13090	COG0671	phosphoesterase, PA-phosphatase related
H0H24_RS13100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H0H24_RS13115	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H0H24_RS13120	COG2951	lytic endotransglycosylase activity
H0H24_RS13170	COG0657	acetylesterase activity
H0H24_RS13175	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H0H24_RS13210	COG0733	neurotransmitter:sodium symporter activity
H0H24_RS13245	COG0583	DNA-binding transcription factor activity
H0H24_RS13250	COG2233	PERMEase
H0H24_RS13265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0H24_RS13300	COG2814	Major facilitator Superfamily
H0H24_RS13305	COG0656	L-ascorbic acid biosynthetic process
H0H24_RS13310	COG0583	DNA-binding transcription factor activity
H0H24_RS13325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H0H24_RS13330	COG1064	alcohol dehydrogenase
H0H24_RS13335	COG2818	Glycosylase
H0H24_RS13350	COG1194	a g-specific adenine glycosylase
H0H24_RS13370	COG2983	Belongs to the UPF0260 family
H0H24_RS13375	COG2133	pyrroloquinoline quinone binding
H0H24_RS13380	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H0H24_RS13385	COG2116	formate transmembrane transporter activity
H0H24_RS13405	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H0H24_RS13410	COG1335	isochorismatase
H0H24_RS13415	COG0385	Bile acid
H0H24_RS13425	COG1683	Conserved Protein
H0H24_RS13445	COG0625	glutathione transferase activity
H0H24_RS13455	COG1113	amino acid transport
H0H24_RS13465	COG0523	cobalamin synthesis protein
H0H24_RS13475	COG2188	Transcriptional regulator
H0H24_RS13505	COG1192	Involved in chromosome partitioning
H0H24_RS13625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0H24_RS13625	COG3433	isochorismatase activity
H0H24_RS13625	COG2226	methyltransferase
H0H24_RS13635	COG1021	2,3-dihydroxybenzoate-AMP ligase
H0H24_RS13640	COG3486	L-lysine 6-monooxygenase (NADPH) activity
H0H24_RS13645	COG0019	diaminopimelate decarboxylase activity
H0H24_RS13665	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H0H24_RS13670	COG4774	siderophore transport
H0H24_RS13685	COG0534	Mate efflux family protein
H0H24_RS13695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H0H24_RS13755	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H0H24_RS13765	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H0H24_RS13770	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H0H24_RS13855	COG0534	Mate efflux family protein
H0H24_RS13860	COG0436	Aminotransferase
H0H24_RS13865	COG2733	membrane
H0H24_RS13880	COG2918	glutathione biosynthetic process
H0H24_RS13895	COG3179	chitinase
H0H24_RS13910	COG3150	esterase
H0H24_RS13920	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H0H24_RS13930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H0H24_RS13940	COG2233	PERMEase
H0H24_RS13945	COG2351	hydroxyisourate hydrolase activity
H0H24_RS13980	COG3706	GGDEF domain
H0H24_RS14000	COG1393	Belongs to the ArsC family
H0H24_RS14005	COG0708	Exodeoxyribonuclease III
H0H24_RS14030	COG0189	ligase activity
H0H24_RS14050	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H0H24_RS14060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H0H24_RS14075	COG4942	peptidase
H0H24_RS14085	COG0508	dehydrogenase complex catalyzes the overall conversion of
H0H24_RS14095	COG2119	membrane
H0H24_RS14100	COG4774	siderophore transport
H0H24_RS14105	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0H24_RS14105	COG0426	domain, Protein
H0H24_RS14130	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H0H24_RS14155	COG1902	pentaerythritol trinitrate reductase activity
H0H24_RS14160	COG1519	Transferase
H0H24_RS14165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0H24_RS14170	COG0668	transmembrane transport
H0H24_RS14180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H0H24_RS14185	COG1335	isochorismatase
H0H24_RS14190	COG1522	sequence-specific DNA binding
H0H24_RS14215	COG2205	protein histidine kinase activity
H0H24_RS14215	COG0784	Response regulator, receiver
H0H24_RS14215	COG2198	Histidine kinase
H0H24_RS14220	COG3162	membrane
H0H24_RS14225	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H0H24_RS14235	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0H24_RS14255	COG1309	transcriptional regulator
H0H24_RS14275	COG0352	thiamine-phosphate diphosphorylase activity
H0H24_RS14275	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0H24_RS14275	COG0351	phosphomethylpyrimidine kinase
H0H24_RS14285	COG2814	Major facilitator Superfamily
H0H24_RS14300	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H0H24_RS14310	COG1113	amino acid transport
H0H24_RS14320	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H0H24_RS14325	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS14335	COG1335	isochorismatase
H0H24_RS14365	COG2814	Major facilitator Superfamily
H0H24_RS14370	COG0583	DNA-binding transcription factor activity
H0H24_RS14390	COG0667	Aldo Keto reductase
H0H24_RS14420	COG1733	regulation of RNA biosynthetic process
H0H24_RS14425	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0H24_RS14485	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H0H24_RS14510	COG1132	(ABC) transporter
H0H24_RS14530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H0H24_RS14560	COG0427	acetyl-CoA hydrolase
H0H24_RS14585	COG0659	secondary active sulfate transmembrane transporter activity
H0H24_RS14590	COG4221	oxidoreductase activity
H0H24_RS14600	COG0488	(ABC) transporter
H0H24_RS14665	COG0833	amino acid
H0H24_RS14710	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H0H24_RS14715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H0H24_RS14730	COG2226	methyltransferase
H0H24_RS14785	COG0493	'glutamate synthase
H0H24_RS14795	COG1704	LemA family
H0H24_RS14800	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H0H24_RS14820	COG3307	-O-antigen
H0H24_RS14840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H0H24_RS14855	COG0194	GDP metabolic process
H0H24_RS14905	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H0H24_RS14925	COG5380	lipid catabolic process
H0H24_RS14930	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H0H24_RS14955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H0H24_RS14960	COG0277	FAD linked oxidase domain protein
H0H24_RS14975	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H0H24_RS14980	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0H24_RS14995	COG1289	transmembrane transporter activity
H0H24_RS15005	COG0628	permease
H0H24_RS15010	COG1192	Involved in chromosome partitioning
H0H24_RS15040	COG0833	amino acid
H0H24_RS15045	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0H24_RS15060	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS15100	COG0583	DNA-binding transcription factor activity
H0H24_RS15150	COG0517	IMP dehydrogenase activity
H0H24_RS15155	COG1983	PspC domain protein
H0H24_RS15175	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS15190	COG0408	coproporphyrinogen oxidase activity
H0H24_RS15210	COG0513	Belongs to the DEAD box helicase family
H0H24_RS15220	COG1127	ABC transporter
H0H24_RS15225	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H0H24_RS15235	COG2854	intermembrane phospholipid transfer
H0H24_RS15245	COG0598	Magnesium transport protein CorA
H0H24_RS15255	COG0494	nUDIX hydrolase
H0H24_RS15260	COG1040	competence protein
H0H24_RS15265	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H0H24_RS15285	COG1946	Acyl-CoA thioesterase
H0H24_RS15290	COG1301	dicarboxylic acid transport
H0H24_RS15305	COG1959	2 iron, 2 sulfur cluster binding
H0H24_RS15310	COG1017	nitric oxide dioxygenase activity
H0H24_RS15310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H0H24_RS15320	COG0433	COG0433 Predicted ATPase
H0H24_RS15325	COG0626	cystathionine gamma-synthase activity
H0H24_RS15480	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS15485	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H0H24_RS15515	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H0H24_RS15520	COG0339	signal peptide processing
H0H24_RS15525	COG0557	exoribonuclease II activity
H0H24_RS15575	COG0179	Fumarylacetoacetate (FAA) hydrolase
H0H24_RS15580	COG2169	Transcriptional regulator
H0H24_RS15585	COG0697	spore germination
H0H24_RS15590	COG1295	ribonuclease BN
H0H24_RS15625	COG1702	phosphate starvation-inducible protein PhoH
H0H24_RS15635	COG0739	heme binding
H0H24_RS15635	COG1196	nuclear chromosome segregation
H0H24_RS15635	COG0741	lytic transglycosylase activity
H0H24_RS15665	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H0H24_RS15670	COG1183	phosphatidylcholine synthase activity
H0H24_RS15710	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS15715	COG1309	transcriptional regulator
H0H24_RS15730	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H0H24_RS15735	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS15755	COG2969	positive regulation of protein catabolic process
H0H24_RS15765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H0H24_RS15775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H0H24_RS15780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H0H24_RS15785	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H0H24_RS15805	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H0H24_RS15815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H0H24_RS15820	COG1408	metallophosphoesterase
H0H24_RS15830	COG2199	diguanylate cyclase activity
H0H24_RS15885	COG1607	acyl-coa hydrolase
H0H24_RS15915	COG2350	Protein conserved in bacteria
H0H24_RS15925	COG0613	PHP domain protein
H0H24_RS15930	COG3781	membrane
H0H24_RS15940	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H0H24_RS15945	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H0H24_RS15955	COG1862	Preprotein translocase
H0H24_RS15985	COG2205	protein histidine kinase activity
H0H24_RS15990	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H0H24_RS16010	COG0726	polysaccharide deacetylase
H0H24_RS16015	COG0463	Glycosyl transferase, family 2
H0H24_RS16020	COG0438	transferase activity, transferring glycosyl groups
H0H24_RS16085	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS16090	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS16100	COG2205	protein histidine kinase activity
H0H24_RS16105	COG0745	RESPONSE REGULATOR receiver
H0H24_RS16110	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H0H24_RS16130	COG2096	Adenosyltransferase
H0H24_RS16180	COG0285	dihydrofolate synthase activity
H0H24_RS16200	COG0450	alkyl hydroperoxide reductase
H0H24_RS16215	COG0477	Major facilitator Superfamily
H0H24_RS16220	COG1272	protein, Hemolysin III
H0H24_RS16250	COG0183	Belongs to the thiolase family
H0H24_RS16255	COG2207	Transcriptional regulator
H0H24_RS16275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0H24_RS16295	COG0183	Belongs to the thiolase family
H0H24_RS16305	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H0H24_RS16305	COG2885	chlorophyll binding
H0H24_RS16315	COG1690	Belongs to the RtcB family
H0H24_RS16320	COG0833	amino acid
H0H24_RS16330	COG2233	PERMEase
H0H24_RS16335	COG1217	gtp-binding protein TYPA
H0H24_RS16360	COG2094	Belongs to the DNA glycosylase MPG family
H0H24_RS16370	COG1902	pentaerythritol trinitrate reductase activity
H0H24_RS16375	COG0679	Auxin Efflux Carrier
H0H24_RS16385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H0H24_RS16390	COG0354	folic acid binding
H0H24_RS16400	COG3189	MarR family transcriptional regulator
H0H24_RS16405	COG2824	Alkylphosphonate utilization operon protein PhnA
H0H24_RS16410	COG3422	double-strand break repair
H0H24_RS16450	COG0840	transmembrane signaling receptor activity
H0H24_RS16470	COG5510	response to toxic substance
H0H24_RS16480	COG2832	Protein of unknown function (DUF454)
H0H24_RS16485	COG1376	ErfK ybiS ycfS ynhG family protein
H0H24_RS16525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H0H24_RS16535	COG1289	transmembrane transporter activity
H0H24_RS16540	COG2814	Major facilitator Superfamily
H0H24_RS16560	COG1115	amino acid carrier protein
H0H24_RS16565	COG1752	Esterase of the alpha-beta hydrolase superfamily
H0H24_RS16570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H0H24_RS16575	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H0H24_RS16600	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0H24_RS16610	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H0H24_RS16615	COG1077	Cell shape determining protein MreB Mrl
H0H24_RS16620	COG1792	Involved in formation and maintenance of cell shape
H0H24_RS16625	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H0H24_RS16630	COG0424	maF-like protein
H0H24_RS16635	COG1530	ribonuclease E activity
H0H24_RS16645	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H0H24_RS16655	COG0560	Phosphoserine phosphatase
H0H24_RS16665	COG2249	NAD(P)H dehydrogenase (quinone) activity
H0H24_RS16690	COG2207	Transcriptional regulator
H0H24_RS16765	COG1214	PFAM Peptidase M22, glycoprotease
H0H24_RS16790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H0H24_RS16795	COG0561	phosphatase activity
H0H24_RS16805	COG2132	Multicopper oxidase
H0H24_RS16825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H0H24_RS16830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H0H24_RS16835	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H0H24_RS16865	COG1063	alcohol dehydrogenase
H0H24_RS16870	COG0583	DNA-binding transcription factor activity
H0H24_RS16875	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS16880	COG2814	Major facilitator Superfamily
H0H24_RS16885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H0H24_RS16890	COG1309	transcriptional regulator
H0H24_RS16905	COG1053	succinate dehydrogenase
H0H24_RS16910	COG0583	DNA-binding transcription factor activity
H0H24_RS16925	COG0583	DNA-binding transcription factor activity
H0H24_RS16935	COG0583	DNA-binding transcription factor activity
H0H24_RS16950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H0H24_RS17000	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H0H24_RS17020	COG0745	RESPONSE REGULATOR receiver
H0H24_RS17035	COG3706	GGDEF domain
H0H24_RS17060	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H0H24_RS17090	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H0H24_RS17095	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H0H24_RS17120	COG0583	DNA-binding transcription factor activity
H0H24_RS17140	COG0668	transmembrane transport
H0H24_RS17150	COG2081	HI0933 family
H0H24_RS17155	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H0H24_RS17185	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0H24_RS17185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H0H24_RS17195	COG0489	protein tyrosine kinase activity
H0H24_RS17245	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H0H24_RS17255	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H0H24_RS17270	COG0730	response to heat
H0H24_RS17280	COG1196	nuclear chromosome segregation
H0H24_RS17300	COG2223	nitrite transmembrane transporter activity
H0H24_RS17305	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H0H24_RS17310	COG1877	trehalose-phosphatase activity
H0H24_RS17315	COG0596	Alpha beta hydrolase
H0H24_RS17315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H0H24_RS17315	COG2226	methyltransferase
H0H24_RS17330	COG4106	trans-aconitate 2-methyltransferase activity
H0H24_RS17345	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H0H24_RS17350	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H0H24_RS17355	COG0009	L-threonylcarbamoyladenylate synthase
H0H24_RS17360	COG3101	peptidyl-lysine hydroxylation
H0H24_RS17365	COG1399	metal-binding, possibly nucleic acid-binding protein
H0H24_RS17390	COG1652	LysM domain
H0H24_RS17395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H0H24_RS17395	COG0352	thiamine-phosphate diphosphorylase activity
H0H24_RS17395	COG0351	phosphomethylpyrimidine kinase
H0H24_RS17405	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H0H24_RS17435	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H0H24_RS17465	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H0H24_RS17480	COG0358	DNA primase activity
H0H24_RS17490	COG0564	pseudouridine synthase activity
H0H24_RS17515	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H0H24_RS17535	COG0583	DNA-binding transcription factor activity
H0H24_RS17540	COG0473	3-isopropylmalate dehydrogenase activity
H0H24_RS17550	COG0657	acetylesterase activity
H0H24_RS17560	COG1012	belongs to the aldehyde dehydrogenase family
H0H24_RS17580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H0H24_RS17580	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H0H24_RS17595	COG1981	membrane
H0H24_RS17645	COG0456	acetyltransferase
H0H24_RS17655	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H0H24_RS17660	COG0492	ferredoxin-NADP+ reductase activity
H0H24_RS17665	COG1674	ftsk spoiiie
H0H24_RS17665	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H0H24_RS17670	COG1280	lysine exporter protein (LysE YggA)
H0H24_RS17685	COG2894	cell division
H0H24_RS17700	COG0204	Acyl-transferase
H0H24_RS17705	COG2885	chlorophyll binding
H0H24_RS17710	COG0210	DNA helicase
H0H24_RS17720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H0H24_RS17735	COG0121	glutamine amidotransferase
H0H24_RS17755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H0H24_RS17760	COG0735	belongs to the Fur family
H0H24_RS17785	COG0420	3'-5' exonuclease activity
H0H24_RS17805	COG1090	epimerase
H0H24_RS17820	COG2050	protein possibly involved in aromatic compounds catabolism
H0H24_RS17830	COG2814	Major facilitator Superfamily
H0H24_RS17835	COG0405	Gamma-glutamyltransferase
H0H24_RS17845	COG0582	viral genome integration into host DNA
H0H24_RS17935	COG2963	transposase activity
H0H24_RS17955	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
H0H24_RS17970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H0H24_RS18005	COG0477	Major facilitator Superfamily
H0H24_RS18020	COG1595	DNA-templated transcription, initiation
H0H24_RS18075	COG0531	amino acid
H0H24_RS18080	COG2040	homocysteine
H0H24_RS18105	COG1309	transcriptional regulator
H0H24_RS18110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0H24_RS18115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H0H24_RS18125	COG1607	acyl-coa hydrolase
H0H24_RS18135	COG0523	cobalamin synthesis protein
H0H24_RS18145	COG4681	YaeQ
H0H24_RS18155	COG1649	PFAM Uncharacterised BCR, COG1649
H0H24_RS18155	COG0726	polysaccharide deacetylase
H0H24_RS18160	COG1215	transferase activity, transferring glycosyl groups
H0H24_RS18170	COG1024	Enoyl-CoA hydratase
H0H24_RS18185	COG1414	Transcriptional regulator
H0H24_RS18205	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS18220	COG2271	Major facilitator Superfamily
H0H24_RS18230	COG2267	carboxylic ester hydrolase activity
H0H24_RS18235	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS18250	COG0028	Belongs to the TPP enzyme family
H0H24_RS18260	COG0477	Major facilitator Superfamily
H0H24_RS18265	COG0242	peptide deformylase activity
H0H24_RS18270	COG2066	Belongs to the glutaminase family
H0H24_RS18275	COG2207	Transcriptional regulator
H0H24_RS18295	COG0583	DNA-binding transcription factor activity
H0H24_RS18300	COG1028	Short-chain dehydrogenase reductase Sdr
H0H24_RS18310	COG3959	Transketolase, thiamine diphosphate binding domain
H0H24_RS18315	COG3958	Transketolase
H0H24_RS18325	COG0306	phosphate transporter
H0H24_RS18345	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H0H24_RS18390	COG4181	ATPase activity
H0H24_RS18395	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H0H24_RS18425	COG0583	DNA-binding transcription factor activity
H0H24_RS18435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H0H24_RS18440	COG1773	rubredoxin
H0H24_RS18490	COG2851	Citrate transporter
H0H24_RS18495	COG1253	flavin adenine dinucleotide binding
H0H24_RS18535	COG0804	urea catabolic process
H0H24_RS18545	COG0830	nickel cation binding
H0H24_RS18560	COG0742	ribosomal rna small subunit methyltransferase
H0H24_RS18565	COG0768	penicillin binding
H0H24_RS18590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H0H24_RS18595	COG2878	Part of a membrane complex involved in electron transport
H0H24_RS18600	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H0H24_RS18610	COG3384	dioxygenase
H0H24_RS18635	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H0H24_RS19010	COG0582	viral genome integration into host DNA
H0H24_RS19025	COG0174	glutamine synthetase
H0H24_RS19035	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H0H24_RS19070	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H0H24_RS19075	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H0H24_RS19080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H0H24_RS19100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H0H24_RS19105	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H0H24_RS19110	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H0H24_RS19125	COG1960	acyl-CoA dehydrogenase activity
H0H24_RS19130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H0H24_RS19135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H0H24_RS19145	COG2223	nitrite transmembrane transporter activity
H0H24_RS19155	COG0024	Methionine aminopeptidase
H0H24_RS19160	COG0052	Belongs to the universal ribosomal protein uS2 family
H0H24_RS19175	COG2207	Transcriptional regulator
H0H24_RS19200	COG2951	lytic endotransglycosylase activity
H0H24_RS19220	COG0842	Transport permease protein
H0H24_RS19225	COG1131	(ABC) transporter
H0H24_RS19230	COG0582	viral genome integration into host DNA
H0H24_RS19405	COG5410	chromosome segregation
H0H24_RS19530	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system