locus-tag	class	description
DN067_RS00010	COG0592	DNA-directed DNA polymerase activity
DN067_RS00020	COG0187	DNA topoisomerase II activity
DN067_RS00030	COG0586	Pfam SNARE associated Golgi protein
DN067_RS00035	COG0488	(ABC) transporter
DN067_RS00060	COG0596	Alpha beta hydrolase
DN067_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DN067_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DN067_RS00115	COG0733	neurotransmitter:sodium symporter activity
DN067_RS00155	COG2233	PERMEase
DN067_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN067_RS00205	COG2814	Major facilitator Superfamily
DN067_RS00210	COG0656	L-ascorbic acid biosynthetic process
DN067_RS00215	COG0583	DNA-binding transcription factor activity
DN067_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN067_RS00235	COG1064	alcohol dehydrogenase
DN067_RS00240	COG2818	Glycosylase
DN067_RS00255	COG1194	a g-specific adenine glycosylase
DN067_RS00275	COG2983	Belongs to the UPF0260 family
DN067_RS00280	COG2133	pyrroloquinoline quinone binding
DN067_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DN067_RS00290	COG2116	formate transmembrane transporter activity
DN067_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN067_RS00315	COG1335	isochorismatase
DN067_RS00320	COG0385	Bile acid
DN067_RS00325	COG0534	Mate efflux family protein
DN067_RS00330	COG1683	Conserved Protein
DN067_RS00350	COG0625	glutathione transferase activity
DN067_RS00360	COG1113	amino acid transport
DN067_RS00370	COG0523	cobalamin synthesis protein
DN067_RS00380	COG2188	Transcriptional regulator
DN067_RS00410	COG0010	Belongs to the arginase family
DN067_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DN067_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DN067_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DN067_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DN067_RS00550	COG0534	Mate efflux family protein
DN067_RS00555	COG0436	Aminotransferase
DN067_RS00560	COG2733	membrane
DN067_RS00575	COG2918	glutathione biosynthetic process
DN067_RS00590	COG0791	NLP P60 protein
DN067_RS00590	COG1388	LysM domain
DN067_RS00605	COG3150	esterase
DN067_RS00615	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS00620	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DN067_RS00630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN067_RS00640	COG2233	PERMEase
DN067_RS00645	COG2351	hydroxyisourate hydrolase activity
DN067_RS00680	COG3706	GGDEF domain
DN067_RS00695	COG1393	Belongs to the ArsC family
DN067_RS00700	COG0708	Exodeoxyribonuclease III
DN067_RS00720	COG0189	ligase activity
DN067_RS00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DN067_RS00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DN067_RS00765	COG4942	peptidase
DN067_RS00775	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN067_RS00785	COG2119	membrane
DN067_RS00790	COG4774	siderophore transport
DN067_RS00795	COG0426	domain, Protein
DN067_RS00795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN067_RS00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DN067_RS00840	COG1902	pentaerythritol trinitrate reductase activity
DN067_RS00845	COG1519	Transferase
DN067_RS00850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DN067_RS00855	COG0668	transmembrane transport
DN067_RS00865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN067_RS00870	COG1335	isochorismatase
DN067_RS00875	COG1522	sequence-specific DNA binding
DN067_RS00880	COG3328	transposase activity
DN067_RS00905	COG0784	Response regulator, receiver
DN067_RS00905	COG2198	Histidine kinase
DN067_RS00905	COG2205	protein histidine kinase activity
DN067_RS00910	COG3162	membrane
DN067_RS00915	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN067_RS00925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN067_RS00945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DN067_RS00950	COG1309	transcriptional regulator
DN067_RS00970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DN067_RS00970	COG0352	thiamine-phosphate diphosphorylase activity
DN067_RS00970	COG0351	phosphomethylpyrimidine kinase
DN067_RS00980	COG2814	Major facilitator Superfamily
DN067_RS00995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DN067_RS01005	COG1113	amino acid transport
DN067_RS01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DN067_RS01020	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS01030	COG1335	isochorismatase
DN067_RS01060	COG2814	Major facilitator Superfamily
DN067_RS01065	COG0583	DNA-binding transcription factor activity
DN067_RS01085	COG0667	Aldo Keto reductase
DN067_RS01120	COG1733	regulation of RNA biosynthetic process
DN067_RS01130	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN067_RS01195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DN067_RS01210	COG2329	Antibiotic biosynthesis monooxygenase
DN067_RS01240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DN067_RS01270	COG0427	acetyl-CoA hydrolase
DN067_RS01295	COG0659	secondary active sulfate transmembrane transporter activity
DN067_RS01300	COG4221	oxidoreductase activity
DN067_RS01305	COG2873	o-acetylhomoserine
DN067_RS01310	COG0488	(ABC) transporter
DN067_RS01395	COG0833	amino acid
DN067_RS01440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DN067_RS01445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DN067_RS01460	COG2226	methyltransferase
DN067_RS01515	COG0070	glutamate synthase
DN067_RS01515	COG0067	glutamate synthase
DN067_RS01515	COG0069	glutamate synthase activity
DN067_RS01520	COG0493	'glutamate synthase
DN067_RS01530	COG1704	LemA family
DN067_RS01535	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DN067_RS01555	COG3307	-O-antigen
DN067_RS01575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DN067_RS01590	COG0194	GDP metabolic process
DN067_RS01640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DN067_RS01660	COG5380	lipid catabolic process
DN067_RS01665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DN067_RS01690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DN067_RS01695	COG0277	FAD linked oxidase domain protein
DN067_RS01705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DN067_RS01710	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN067_RS01725	COG1289	transmembrane transporter activity
DN067_RS01735	COG0628	permease
DN067_RS01740	COG1192	Involved in chromosome partitioning
DN067_RS01770	COG0833	amino acid
DN067_RS01775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DN067_RS01780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DN067_RS01790	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS01830	COG0583	DNA-binding transcription factor activity
DN067_RS01875	COG0517	IMP dehydrogenase activity
DN067_RS01880	COG1983	PspC domain protein
DN067_RS01890	COG1960	acyl-CoA dehydrogenase activity
DN067_RS01905	COG0408	coproporphyrinogen oxidase activity
DN067_RS01925	COG0513	Belongs to the DEAD box helicase family
DN067_RS01930	COG1127	ABC transporter
DN067_RS01935	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DN067_RS01945	COG2854	intermembrane phospholipid transfer
DN067_RS01955	COG0598	Magnesium transport protein CorA
DN067_RS01965	COG0494	nUDIX hydrolase
DN067_RS01970	COG1040	competence protein
DN067_RS01975	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DN067_RS01995	COG1946	Acyl-CoA thioesterase
DN067_RS02000	COG1301	dicarboxylic acid transport
DN067_RS02015	COG1959	2 iron, 2 sulfur cluster binding
DN067_RS02020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN067_RS02020	COG1017	nitric oxide dioxygenase activity
DN067_RS02025	COG0433	COG0433 Predicted ATPase
DN067_RS02030	COG0626	cystathionine gamma-synthase activity
DN067_RS02185	COG1960	acyl-CoA dehydrogenase activity
DN067_RS02190	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DN067_RS02220	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DN067_RS02225	COG0339	signal peptide processing
DN067_RS02230	COG0557	exoribonuclease II activity
DN067_RS02275	COG0179	Fumarylacetoacetate (FAA) hydrolase
DN067_RS02280	COG2169	Transcriptional regulator
DN067_RS02285	COG0697	spore germination
DN067_RS02290	COG1295	ribonuclease BN
DN067_RS02325	COG1702	phosphate starvation-inducible protein PhoH
DN067_RS02335	COG0739	heme binding
DN067_RS02335	COG1196	nuclear chromosome segregation
DN067_RS02335	COG0741	lytic transglycosylase activity
DN067_RS02365	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DN067_RS02370	COG1183	phosphatidylcholine synthase activity
DN067_RS02415	COG1960	acyl-CoA dehydrogenase activity
DN067_RS02420	COG1309	transcriptional regulator
DN067_RS02435	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DN067_RS02440	COG1960	acyl-CoA dehydrogenase activity
DN067_RS02460	COG2969	positive regulation of protein catabolic process
DN067_RS02470	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DN067_RS02485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DN067_RS02490	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DN067_RS02510	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DN067_RS02520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN067_RS02525	COG1408	metallophosphoesterase
DN067_RS02535	COG2199	diguanylate cyclase activity
DN067_RS02595	COG1607	acyl-coa hydrolase
DN067_RS02625	COG2350	Protein conserved in bacteria
DN067_RS02635	COG0613	PHP domain protein
DN067_RS02640	COG3781	membrane
DN067_RS02650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DN067_RS02655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DN067_RS02665	COG1862	Preprotein translocase
DN067_RS02695	COG2205	protein histidine kinase activity
DN067_RS02700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DN067_RS02730	COG0726	polysaccharide deacetylase
DN067_RS02735	COG0463	Glycosyl transferase, family 2
DN067_RS02740	COG0438	transferase activity, transferring glycosyl groups
DN067_RS02805	COG0625	glutathione transferase activity
DN067_RS02810	COG0583	DNA-binding transcription factor activity
DN067_RS02815	COG1960	acyl-CoA dehydrogenase activity
DN067_RS02820	COG1960	acyl-CoA dehydrogenase activity
DN067_RS02830	COG2205	protein histidine kinase activity
DN067_RS02835	COG0745	RESPONSE REGULATOR receiver
DN067_RS02840	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DN067_RS02860	COG2096	Adenosyltransferase
DN067_RS02910	COG0285	dihydrofolate synthase activity
DN067_RS02930	COG0450	alkyl hydroperoxide reductase
DN067_RS02945	COG0477	Major facilitator Superfamily
DN067_RS02950	COG1272	protein, Hemolysin III
DN067_RS02980	COG0183	Belongs to the thiolase family
DN067_RS02985	COG2207	Transcriptional regulator
DN067_RS03005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN067_RS03025	COG0183	Belongs to the thiolase family
DN067_RS03035	COG2885	chlorophyll binding
DN067_RS03035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DN067_RS03045	COG1690	Belongs to the RtcB family
DN067_RS03050	COG0833	amino acid
DN067_RS03060	COG2233	PERMEase
DN067_RS03065	COG1217	gtp-binding protein TYPA
DN067_RS03090	COG2094	Belongs to the DNA glycosylase MPG family
DN067_RS03095	COG4772	TonB-dependent receptor
DN067_RS03110	COG1902	pentaerythritol trinitrate reductase activity
DN067_RS03115	COG0679	Auxin Efflux Carrier
DN067_RS03125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DN067_RS03130	COG0354	folic acid binding
DN067_RS03140	COG3189	MarR family transcriptional regulator
DN067_RS03145	COG2824	Alkylphosphonate utilization operon protein PhnA
DN067_RS03150	COG3422	double-strand break repair
DN067_RS03190	COG0840	transmembrane signaling receptor activity
DN067_RS03210	COG5510	response to toxic substance
DN067_RS03220	COG2832	Protein of unknown function (DUF454)
DN067_RS03225	COG1376	ErfK ybiS ycfS ynhG family protein
DN067_RS03265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DN067_RS03275	COG1289	transmembrane transporter activity
DN067_RS03280	COG2814	Major facilitator Superfamily
DN067_RS03300	COG1115	amino acid carrier protein
DN067_RS03305	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN067_RS03310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DN067_RS03315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DN067_RS03355	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DN067_RS03365	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DN067_RS03370	COG1077	Cell shape determining protein MreB Mrl
DN067_RS03375	COG1792	Involved in formation and maintenance of cell shape
DN067_RS03380	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DN067_RS03385	COG0424	maF-like protein
DN067_RS03390	COG1530	ribonuclease E activity
DN067_RS03400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN067_RS03410	COG0560	Phosphoserine phosphatase
DN067_RS03420	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN067_RS03445	COG2207	Transcriptional regulator
DN067_RS03465	COG1113	amino acid transport
DN067_RS03470	COG2828	Protein conserved in bacteria
DN067_RS03475	COG0142	geranyltranstransferase activity
DN067_RS03480	COG2315	Protein conserved in bacteria
DN067_RS03495	COG1752	Esterase of the alpha-beta hydrolase superfamily
DN067_RS03515	COG2194	sulfuric ester hydrolase activity
DN067_RS03520	COG0745	RESPONSE REGULATOR receiver
DN067_RS03525	COG0642	Histidine kinase
DN067_RS03535	COG0004	ammonium transporteR
DN067_RS03545	COG0583	DNA-binding transcription factor activity
DN067_RS03565	COG0525	valine-tRNA ligase activity
DN067_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS03585	COG0393	Putative heavy-metal-binding
DN067_RS03590	COG0393	Putative heavy-metal-binding
DN067_RS03595	COG1538	Outer membrane efflux protein
DN067_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN067_RS03610	COG0671	phosphoesterase, PA-phosphatase related
DN067_RS03640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DN067_RS03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DN067_RS03655	COG1648	precorrin-2 dehydrogenase activity
DN067_RS03660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DN067_RS03665	COG1733	regulation of RNA biosynthetic process
DN067_RS03675	COG0531	amino acid
DN067_RS03690	COG0321	lipoyl(octanoyl) transferase activity
DN067_RS03695	COG2921	Belongs to the UPF0250 family
DN067_RS03735	COG2009	succinate dehydrogenase
DN067_RS03740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DN067_RS03745	COG1053	succinate dehydrogenase
DN067_RS03750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DN067_RS03775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN067_RS03795	COG2354	Protein conserved in bacteria
DN067_RS03800	COG2321	neutral zinc metallopeptidase
DN067_RS03830	COG2843	Capsule synthesis protein
DN067_RS03845	COG0589	response to stress
DN067_RS03865	COG0505	Belongs to the CarA family
DN067_RS03890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DN067_RS03895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DN067_RS03945	COG0477	Major facilitator Superfamily
DN067_RS03950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DN067_RS03965	COG1597	lipid kinase activity
DN067_RS03970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DN067_RS04000	COG0584	glycerophosphoryl diester phosphodiesterase
DN067_RS04020	COG0741	lytic transglycosylase activity
DN067_RS04045	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DN067_RS04060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN067_RS04090	COG0778	Nitroreductase
DN067_RS04105	COG1929	Belongs to the glycerate kinase type-1 family
DN067_RS04110	COG0243	molybdopterin cofactor binding
DN067_RS04115	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DN067_RS04120	COG3339	Conserved Protein
DN067_RS04130	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DN067_RS04145	COG1113	amino acid transport
DN067_RS04155	COG0019	diaminopimelate decarboxylase activity
DN067_RS04165	COG1280	lysine exporter protein (LysE YggA)
DN067_RS04170	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DN067_RS04200	COG0463	Glycosyl transferase, family 2
DN067_RS04220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN067_RS04250	COG4591	ABC-type transport system involved in lipoprotein release permease component
DN067_RS04255	COG1136	(ABC) transporter
DN067_RS04260	COG0658	competence protein
DN067_RS04260	COG2333	competence protein COMEC
DN067_RS04270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DN067_RS04270	COG0616	signal peptide processing
DN067_RS04275	COG0596	Alpha beta hydrolase
DN067_RS04280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DN067_RS04290	COG0628	permease
DN067_RS04325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN067_RS04345	COG0823	Involved in the tonB-independent uptake of proteins
DN067_RS04365	COG0824	Thioesterase
DN067_RS04370	COG1473	amidohydrolase
DN067_RS04390	COG0047	phosphoribosylformylglycinamidine synthase activity
DN067_RS04390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DN067_RS04395	COG2814	Major facilitator Superfamily
DN067_RS04405	COG1024	Enoyl-CoA hydratase
DN067_RS04410	COG1056	cytidyltransferase-related domain
DN067_RS04410	COG1051	belongs to the nudix hydrolase family
DN067_RS04420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DN067_RS04435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DN067_RS04450	COG4625	pathogenesis
DN067_RS04455	COG0583	DNA-binding transcription factor activity
DN067_RS04460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DN067_RS04465	COG4208	sulfate ABC transporter
DN067_RS04470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DN067_RS04480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DN067_RS04485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DN067_RS04490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DN067_RS04510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN067_RS04525	COG0681	Belongs to the peptidase S26 family
DN067_RS04540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DN067_RS04550	COG1381	Involved in DNA repair and RecF pathway recombination
DN067_RS04555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DN067_RS04565	COG4221	oxidoreductase activity
DN067_RS04595	COG0436	Aminotransferase
DN067_RS04615	COG0556	nucleotide-excision repair
DN067_RS04670	COG2070	2-Nitropropane dioxygenase
DN067_RS04700	COG1215	transferase activity, transferring glycosyl groups
DN067_RS04715	COG0415	Belongs to the DNA photolyase family
DN067_RS04725	COG1252	NADH dehydrogenase
DN067_RS04730	COG1686	Belongs to the peptidase S11 family
DN067_RS04745	COG1187	pseudouridine synthase activity
DN067_RS04770	COG0477	Major facilitator Superfamily
DN067_RS04775	COG0583	DNA-binding transcription factor activity
DN067_RS04780	COG1823	symporter activity
DN067_RS04790	COG0612	Peptidase, M16
DN067_RS04815	COG0352	thiamine-phosphate diphosphorylase activity
DN067_RS04850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN067_RS04865	COG1309	transcriptional regulator
DN067_RS04875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DN067_RS04880	COG0076	glutamate decarboxylase activity
DN067_RS04890	COG1522	sequence-specific DNA binding
DN067_RS04895	COG3961	Belongs to the TPP enzyme family
DN067_RS04900	COG1113	amino acid transport
DN067_RS04905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DN067_RS04910	COG0573	inorganic phosphate transmembrane transporter activity
DN067_RS04920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DN067_RS04925	COG0616	signal peptide processing
DN067_RS04935	COG3328	transposase activity
DN067_RS04965	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DN067_RS04970	COG1686	Belongs to the peptidase S11 family
DN067_RS04995	COG0583	DNA-binding transcription factor activity
DN067_RS05000	COG1067	ATP-dependent peptidase activity
DN067_RS05045	COG1966	Carbon starvation protein
DN067_RS05050	COG2879	small protein
DN067_RS05085	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DN067_RS05085	COG2508	Transcriptional regulator
DN067_RS05105	COG1113	amino acid transport
DN067_RS05110	COG0583	DNA-binding transcription factor activity
DN067_RS05115	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN067_RS05120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN067_RS05130	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS05135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN067_RS05140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN067_RS05140	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DN067_RS05175	COG2814	Major facilitator Superfamily
DN067_RS05180	COG4948	Mandelate Racemase Muconate Lactonizing
DN067_RS05190	COG1309	transcriptional regulator
DN067_RS05210	COG1741	Belongs to the pirin family
DN067_RS05220	COG2964	Protein conserved in bacteria
DN067_RS05235	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN067_RS05240	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN067_RS05245	COG4605	iron ion homeostasis
DN067_RS05250	COG4604	ABC transporter, ATP-binding protein
DN067_RS05255	COG4607	ABC-type enterochelin transport system periplasmic component
DN067_RS05260	COG4774	siderophore transport
DN067_RS05270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DN067_RS05275	COG1021	2,3-dihydroxybenzoate-AMP ligase
DN067_RS05280	COG3433	isochorismatase activity
DN067_RS05280	COG1535	isochorismatase
DN067_RS05295	COG1132	(ABC) transporter
DN067_RS05300	COG1132	(ABC) transporter
DN067_RS05305	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DN067_RS05315	COG1169	isochorismate synthase
DN067_RS05330	COG3739	integral membrane protein
DN067_RS05355	COG0302	gtp cyclohydrolase
DN067_RS05365	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DN067_RS05395	COG0308	aminopeptidase N
DN067_RS05400	COG0512	Glutamine amidotransferase of anthranilate synthase
DN067_RS05415	COG0174	glutamine synthetase
DN067_RS05425	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DN067_RS05460	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DN067_RS05465	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DN067_RS05470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DN067_RS05490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DN067_RS05495	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DN067_RS05500	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DN067_RS05515	COG1960	acyl-CoA dehydrogenase activity
DN067_RS05520	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DN067_RS05525	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN067_RS05535	COG2223	nitrite transmembrane transporter activity
DN067_RS05545	COG0024	Methionine aminopeptidase
DN067_RS05550	COG0052	Belongs to the universal ribosomal protein uS2 family
DN067_RS05565	COG2207	Transcriptional regulator
DN067_RS05590	COG2951	lytic endotransglycosylase activity
DN067_RS05595	COG0772	Belongs to the SEDS family
DN067_RS05610	COG0842	Transport permease protein
DN067_RS05615	COG1131	(ABC) transporter
DN067_RS05660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN067_RS05675	COG4215	(ABC) transporter
DN067_RS05680	COG4160	amino acid transport
DN067_RS05685	COG4598	ABC transporter
DN067_RS05695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DN067_RS05700	COG0826	peptidase U32
DN067_RS05705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN067_RS05720	COG1720	tRNA m6t6A37 methyltransferase activity
DN067_RS05730	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DN067_RS05745	COG0642	Histidine kinase
DN067_RS05755	COG0494	nUDIX hydrolase
DN067_RS05765	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DN067_RS05770	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DN067_RS05775	COG3139	Protein of unknown function (DUF1315)
DN067_RS05780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DN067_RS05790	COG1301	dicarboxylic acid transport
DN067_RS05795	COG1960	acyl-CoA dehydrogenase activity
DN067_RS05800	COG2819	hydrolase of the alpha beta superfamily
DN067_RS05810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DN067_RS05820	COG2195	Cleaves the N-terminal amino acid of tripeptides
DN067_RS05825	COG1234	tRNA 3'-trailer cleavage
DN067_RS05855	COG2363	Small membrane protein
DN067_RS05875	COG0513	Belongs to the DEAD box helicase family
DN067_RS05885	COG0778	Nitroreductase
DN067_RS05915	COG1286	toxin biosynthetic process
DN067_RS05940	COG4783	chaperone-mediated protein folding
DN067_RS05945	COG1610	YqeY-like protein
DN067_RS06045	COG3111	PFAM Bacterial OB fold (BOF) protein
DN067_RS06070	COG3243	poly(R)-hydroxyalkanoic acid synthase
DN067_RS06075	COG0786	glutamate:sodium symporter activity
DN067_RS06085	COG2186	Transcriptional regulator
DN067_RS06135	COG0477	Major facilitator Superfamily
DN067_RS06165	COG2985	domain, Protein
DN067_RS06175	COG2995	paraquat-inducible protein a
DN067_RS06180	COG3008	intermembrane lipid transfer
DN067_RS06180	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DN067_RS06205	COG0482	sulfurtransferase activity
DN067_RS06220	COG0488	(ABC) transporter
DN067_RS06225	COG3173	Aminoglycoside phosphotransferase
DN067_RS06235	COG2433	Pfam Transposase IS66
DN067_RS06275	COG1301	dicarboxylic acid transport
DN067_RS06285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN067_RS06290	COG2011	ABC-type metal ion transport system permease component
DN067_RS06295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DN067_RS06300	COG1464	Belongs to the NlpA lipoprotein family
DN067_RS06305	COG0151	Belongs to the GarS family
DN067_RS06310	COG0138	bifunctional purine biosynthesis protein purh
DN067_RS06315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DN067_RS06345	COG2308	Evidence 4 Homologs of previously reported genes of
DN067_RS06355	COG1305	Transglutaminase-like
DN067_RS06365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DN067_RS06370	COG0305	Participates in initiation and elongation during chromosome replication
DN067_RS06395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DN067_RS06405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DN067_RS06410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DN067_RS06435	COG0726	polysaccharide deacetylase
DN067_RS06435	COG1649	PFAM Uncharacterised BCR, COG1649
DN067_RS06440	COG1215	transferase activity, transferring glycosyl groups
DN067_RS06445	COG3658	cytochrome
DN067_RS06455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN067_RS06475	COG0583	DNA-binding transcription factor activity
DN067_RS06495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN067_RS06500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN067_RS06515	COG1960	acyl-CoA dehydrogenase activity
DN067_RS06520	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN067_RS06525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN067_RS06550	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DN067_RS06555	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DN067_RS06565	COG2205	protein histidine kinase activity
DN067_RS06570	COG0745	RESPONSE REGULATOR receiver
DN067_RS06575	COG0174	glutamine synthetase
DN067_RS06595	COG0729	surface antigen
DN067_RS06625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN067_RS06630	COG2814	Major facilitator Superfamily
DN067_RS06645	COG0583	DNA-binding transcription factor activity
DN067_RS06660	COG1187	pseudouridine synthase activity
DN067_RS06680	COG0802	atpase or kinase
DN067_RS06685	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DN067_RS06695	COG1923	regulation of RNA biosynthetic process
DN067_RS06700	COG0697	spore germination
DN067_RS06715	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DN067_RS06725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DN067_RS06730	COG0519	Catalyzes the synthesis of GMP from XMP
DN067_RS06730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DN067_RS06735	COG4302	ethanolamine ammonia-lyase activity
DN067_RS06740	COG4303	Ethanolamine ammonia lyase large subunit
DN067_RS06745	COG0531	amino acid
DN067_RS06765	COG1454	alcohol dehydrogenase
DN067_RS06770	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DN067_RS06780	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DN067_RS06800	COG0308	aminopeptidase N
DN067_RS06830	COG1605	Chorismate mutase
DN067_RS06850	COG1309	transcriptional regulator
DN067_RS06860	COG0668	transmembrane transport
DN067_RS06895	COG4773	Receptor
DN067_RS06915	COG0488	(ABC) transporter
DN067_RS06920	COG0589	response to stress
DN067_RS06935	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DN067_RS06945	COG3135	benzoate transporter
DN067_RS06950	COG1522	sequence-specific DNA binding
DN067_RS06960	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DN067_RS06965	COG0583	DNA-binding transcription factor activity
DN067_RS06975	COG0183	Belongs to the thiolase family
DN067_RS06985	COG2030	dehydratase
DN067_RS06990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN067_RS07005	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DN067_RS07015	COG0824	Thioesterase
DN067_RS07020	COG1454	alcohol dehydrogenase
DN067_RS07030	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DN067_RS07050	COG0069	glutamate synthase activity
DN067_RS07215	COG5410	chromosome segregation
DN067_RS07340	COG0739	heme binding
DN067_RS07405	COG2814	Major facilitator Superfamily
DN067_RS07420	COG0511	ligase activity, forming carbon-carbon bonds
DN067_RS07440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN067_RS07440	COG1116	anion transmembrane transporter activity
DN067_RS07445	COG0745	RESPONSE REGULATOR receiver
DN067_RS07455	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN067_RS07455	COG2146	nitrite reductase [NAD(P)H] activity
DN067_RS07460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN067_RS07465	COG0243	molybdopterin cofactor binding
DN067_RS07475	COG0243	molybdopterin cofactor binding
DN067_RS07480	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DN067_RS07495	COG0315	cyclic pyranopterin monophosphate synthase activity
DN067_RS07495	COG0521	Mo-molybdopterin cofactor biosynthetic process
DN067_RS07500	COG0303	'Molybdopterin
DN067_RS07510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN067_RS07515	COG0697	spore germination
DN067_RS07535	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DN067_RS07540	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DN067_RS07600	COG2204	response regulator
DN067_RS07605	COG3852	Histidine kinase
DN067_RS07630	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DN067_RS07635	COG0575	Belongs to the CDS family
DN067_RS07670	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DN067_RS07690	COG2137	regulation of response to DNA damage stimulus
DN067_RS07700	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DN067_RS07705	COG1011	Hydrolase
DN067_RS07730	COG1522	sequence-specific DNA binding
DN067_RS07740	COG1113	amino acid transport
DN067_RS07755	COG0659	secondary active sulfate transmembrane transporter activity
DN067_RS07760	COG2135	peptidase activity
DN067_RS07775	COG3300	MHYT domain
DN067_RS07775	COG5001	Diguanylate cyclase
DN067_RS07795	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DN067_RS07795	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN067_RS07795	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DN067_RS07800	COG1105	Belongs to the carbohydrate kinase PfkB family
DN067_RS07805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DN067_RS07805	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN067_RS07835	COG0024	Methionine aminopeptidase
DN067_RS07840	COG0583	DNA-binding transcription factor activity
DN067_RS07850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DN067_RS07855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DN067_RS07860	COG0517	IMP dehydrogenase activity
DN067_RS07860	COG0516	GMP reductase activity
DN067_RS07885	COG0552	protein localization to endoplasmic reticulum
DN067_RS07895	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DN067_RS07910	COG4890	Cyd operon protein YbgT
DN067_RS07915	COG1294	oxidase, subunit
DN067_RS07935	COG1585	Membrane protein implicated in regulation of membrane protease activity
DN067_RS07945	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DN067_RS07950	COG4774	siderophore transport
DN067_RS07965	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DN067_RS07970	COG0569	domain protein
DN067_RS07975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DN067_RS08005	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DN067_RS08010	COG0542	response to heat
DN067_RS08035	COG0446	pyridine nucleotide-disulphide oxidoreductase
DN067_RS08035	COG1902	pentaerythritol trinitrate reductase activity
DN067_RS08080	COG2323	membrane
DN067_RS08085	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DN067_RS08095	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DN067_RS08100	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DN067_RS08105	COG0183	Belongs to the thiolase family
DN067_RS08110	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DN067_RS08115	COG0596	Alpha beta hydrolase
DN067_RS08120	COG2271	Major facilitator Superfamily
DN067_RS08125	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN067_RS08130	COG3485	protocatechuate 3,4-dioxygenase
DN067_RS08135	COG3485	protocatechuate 3,4-dioxygenase
DN067_RS08140	COG0710	3-dehydroquinate dehydratase activity
DN067_RS08145	COG3420	alginic acid biosynthetic process
DN067_RS08150	COG3659	wide pore channel activity
DN067_RS08155	COG4993	Dehydrogenase
DN067_RS08165	COG2391	methyltransferase activity
DN067_RS08180	COG1414	Transcriptional regulator
DN067_RS08185	COG0583	DNA-binding transcription factor activity
DN067_RS08190	COG1960	acyl-CoA dehydrogenase activity
DN067_RS08215	COG2814	Major facilitator Superfamily
DN067_RS08225	COG0154	amidase activity
DN067_RS08245	COG4638	Rieske (2fe-2S)
DN067_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS08265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN067_RS08275	COG3733	amine oxidase
DN067_RS08285	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS08295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DN067_RS08300	COG0183	Belongs to the thiolase family
DN067_RS08305	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DN067_RS08310	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DN067_RS08320	COG4829	muconolactone delta-isomerase
DN067_RS08325	COG4948	Mandelate Racemase Muconate Lactonizing
DN067_RS08330	COG0583	DNA-binding transcription factor activity
DN067_RS08340	COG2186	Transcriptional regulator
DN067_RS08360	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS08380	COG1960	acyl-CoA dehydrogenase activity
DN067_RS08385	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS08390	COG3829	transcription factor binding
DN067_RS08400	COG3162	membrane
DN067_RS08415	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS08430	COG0753	catalase activity
DN067_RS08455	COG1846	Transcriptional regulator
DN067_RS08460	COG1902	pentaerythritol trinitrate reductase activity
DN067_RS08460	COG0446	pyridine nucleotide-disulphide oxidoreductase
DN067_RS08470	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DN067_RS08500	COG1309	transcriptional regulator
DN067_RS08510	COG1335	isochorismatase
DN067_RS08515	COG0583	DNA-binding transcription factor activity
DN067_RS08525	COG0475	glutathione-regulated potassium exporter activity
DN067_RS08525	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN067_RS08535	COG1473	amidohydrolase
DN067_RS08550	COG2831	hemolysin activation secretion protein
DN067_RS08555	COG3210	domain, Protein
DN067_RS08585	COG2188	Transcriptional regulator
DN067_RS08600	COG0583	DNA-binding transcription factor activity
DN067_RS08630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DN067_RS08650	COG1566	PFAM secretion protein HlyD family protein
DN067_RS08665	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS08670	COG0129	dihydroxy-acid dehydratase activity
DN067_RS08680	COG0583	DNA-binding transcription factor activity
DN067_RS08685	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DN067_RS08695	COG2084	Dehydrogenase
DN067_RS08700	COG2207	Transcriptional regulator
DN067_RS08715	COG1064	alcohol dehydrogenase
DN067_RS08725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DN067_RS08730	COG1120	ATPase activity
DN067_RS08750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DN067_RS08870	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DN067_RS08925	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS08940	COG2207	Transcriptional regulator
DN067_RS08950	COG2205	protein histidine kinase activity
DN067_RS08955	COG0745	RESPONSE REGULATOR receiver
DN067_RS08960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN067_RS08965	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN067_RS08970	COG1538	Outer membrane efflux protein
DN067_RS08980	COG2072	flavoprotein involved in K transport
DN067_RS09000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN067_RS09020	COG3539	Fimbrial protein
DN067_RS09050	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DN067_RS09060	COG0753	catalase activity
DN067_RS09075	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DN067_RS09140	COG1535	isochorismatase
DN067_RS09140	COG3433	isochorismatase activity
DN067_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS09150	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DN067_RS09155	COG4149	molybdate abc transporter
DN067_RS09160	COG0725	ABC transporter, periplasmic molybdate-binding protein
DN067_RS09170	COG4638	Rieske (2fe-2S)
DN067_RS09175	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DN067_RS09180	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN067_RS09180	COG0543	2 iron, 2 sulfur cluster binding
DN067_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS09220	COG2207	Transcriptional regulator
DN067_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS09235	COG2610	gluconate transmembrane transporter activity
DN067_RS09245	COG0583	DNA-binding transcription factor activity
DN067_RS09255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DN067_RS09260	COG2031	fatty acid transporter
DN067_RS09265	COG0183	Belongs to the thiolase family
DN067_RS09270	COG0583	DNA-binding transcription factor activity
DN067_RS09275	COG0583	DNA-binding transcription factor activity
DN067_RS09290	COG1027	Aspartate ammonia-lyase
DN067_RS09300	COG0477	Major facilitator Superfamily
DN067_RS09320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN067_RS09325	COG4521	taurine ABC transporter
DN067_RS09340	COG2188	Transcriptional regulator
DN067_RS09350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DN067_RS09355	COG1733	regulation of RNA biosynthetic process
DN067_RS09360	COG2207	Transcriptional regulator
DN067_RS09360	COG3708	Transcriptional regulator
DN067_RS09375	COG0730	response to heat
DN067_RS09385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN067_RS09385	COG3453	Protein conserved in bacteria
DN067_RS09395	COG3781	membrane
DN067_RS09400	COG1063	alcohol dehydrogenase
DN067_RS09410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DN067_RS09415	COG0508	dehydrogenase complex catalyzes the overall conversion of
DN067_RS09420	COG0022	dehydrogenase e1 component
DN067_RS09425	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DN067_RS09430	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DN067_RS09445	COG3706	GGDEF domain
DN067_RS09460	COG0133	tryptophan synthase activity
DN067_RS09470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DN067_RS09505	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DN067_RS09530	COG2226	methyltransferase
DN067_RS09585	COG0842	Transport permease protein
DN067_RS09590	COG0842	Transport permease protein
DN067_RS09595	COG1131	(ABC) transporter
DN067_RS09610	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DN067_RS09615	COG4773	Receptor
DN067_RS09635	COG0730	response to heat
DN067_RS09640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DN067_RS09660	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DN067_RS09720	COG4264	IucA IucC family
DN067_RS09725	COG4264	IucA IucC family
DN067_RS09745	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DN067_RS09760	COG1960	acyl-CoA dehydrogenase activity
DN067_RS09765	COG1960	acyl-CoA dehydrogenase activity
DN067_RS09770	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DN067_RS09775	COG2207	Transcriptional regulator
DN067_RS09780	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN067_RS09785	COG0776	regulation of translation
DN067_RS09810	COG0822	iron-sulfur transferase activity
DN067_RS09815	COG0316	Belongs to the HesB IscA family
DN067_RS09845	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DN067_RS09865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DN067_RS09870	COG0702	epimerase
DN067_RS09905	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DN067_RS09915	COG0339	signal peptide processing
DN067_RS09965	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DN067_RS09970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DN067_RS10000	COG0776	regulation of translation
DN067_RS10065	COG0084	hydrolase, TatD family'
DN067_RS10090	COG1132	(ABC) transporter
DN067_RS10100	COG0811	peptide transport
DN067_RS10105	COG1475	DNA binding
DN067_RS10110	COG1192	Involved in chromosome partitioning
DN067_RS10120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DN067_RS10135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DN067_RS10140	COG0191	fructose-bisphosphate aldolase activity
DN067_RS10160	COG0424	maF-like protein
DN067_RS10165	COG2850	peptidyl-arginine hydroxylation
DN067_RS10175	COG0640	Transcriptional regulator
DN067_RS10190	COG3619	membrane
DN067_RS10195	COG3122	Protein conserved in bacteria
DN067_RS10200	COG1132	(ABC) transporter
DN067_RS10220	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DN067_RS10225	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DN067_RS10235	COG0506	proline dehydrogenase activity
DN067_RS10235	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DN067_RS10235	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DN067_RS10240	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DN067_RS10255	COG3698	Phosphodiester glycosidase
DN067_RS10265	COG2353	YceI-like domain
DN067_RS10275	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DN067_RS10320	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DN067_RS10320	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DN067_RS10345	COG3539	Fimbrial protein
DN067_RS10350	COG3121	Chaperone
DN067_RS10380	COG0697	spore germination
DN067_RS10390	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DN067_RS10400	COG0583	DNA-binding transcription factor activity
DN067_RS10420	COG1309	transcriptional regulator
DN067_RS10435	COG1522	sequence-specific DNA binding
DN067_RS10445	COG1126	abc transporter atp-binding protein
DN067_RS10450	COG0765	amino acid transport
DN067_RS10455	COG0765	amino acid transport
DN067_RS10485	COG1464	Belongs to the NlpA lipoprotein family
DN067_RS10495	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DN067_RS10500	COG2011	ABC-type metal ion transport system permease component
DN067_RS10505	COG0012	GTP binding
DN067_RS10530	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DN067_RS10570	COG0386	Belongs to the glutathione peroxidase family
DN067_RS10580	COG0436	Aminotransferase
DN067_RS10620	COG3634	alkyl hydroperoxide reductase activity
DN067_RS10635	COG0583	DNA-binding transcription factor activity
DN067_RS10640	COG0798	PFAM Bile acid sodium symporter
DN067_RS10645	COG0640	Transcriptional regulator
DN067_RS10660	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DN067_RS10670	COG0583	DNA-binding transcription factor activity
DN067_RS10680	COG1953	Uracil, thiamine, allantoin
DN067_RS10690	COG2175	clavaminate synthase activity
DN067_RS10695	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN067_RS10700	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DN067_RS10705	COG4521	taurine ABC transporter
DN067_RS10715	COG0477	Major facilitator Superfamily
DN067_RS10740	COG1271	oxidase subunit
DN067_RS10745	COG1294	oxidase, subunit
DN067_RS10755	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DN067_RS10775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DN067_RS10795	COG3052	prosthetic group binding
DN067_RS10800	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DN067_RS10810	COG2814	Major facilitator Superfamily
DN067_RS10830	COG1346	cytolysis
DN067_RS10840	COG0583	DNA-binding transcription factor activity
DN067_RS10845	COG0625	glutathione transferase activity
DN067_RS10850	COG0625	glutathione transferase activity
DN067_RS10855	COG0583	DNA-binding transcription factor activity
DN067_RS10870	COG1045	serine acetyltransferase
DN067_RS10875	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DN067_RS10880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DN067_RS10890	COG1280	lysine exporter protein (LysE YggA)
DN067_RS10905	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN067_RS10910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN067_RS10915	COG1126	abc transporter atp-binding protein
DN067_RS10920	COG0765	amino acid transport
DN067_RS10925	COG0765	amino acid transport
DN067_RS10945	COG0784	Response regulator, receiver
DN067_RS10945	COG2205	protein histidine kinase activity
DN067_RS10965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DN067_RS10985	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS11030	COG0583	DNA-binding transcription factor activity
DN067_RS11050	COG0318	PFAM AMP-dependent synthetase and ligase
DN067_RS11055	COG1309	transcriptional regulator
DN067_RS11060	COG1960	acyl-CoA dehydrogenase activity
DN067_RS11065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DN067_RS11070	COG1024	Enoyl-CoA hydratase
DN067_RS11075	COG4770	biotin carboxylase activity
DN067_RS11085	COG0583	DNA-binding transcription factor activity
DN067_RS11100	COG1960	acyl-CoA dehydrogenase activity
DN067_RS11110	COG2814	Major facilitator Superfamily
DN067_RS11120	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DN067_RS11125	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DN067_RS11130	COG2814	Major facilitator Superfamily
DN067_RS11135	COG1960	acyl-CoA dehydrogenase activity
DN067_RS11140	COG1024	Enoyl-CoA hydratase
DN067_RS11145	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS11150	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN067_RS11155	COG0183	Belongs to the thiolase family
DN067_RS11165	COG2814	Major facilitator Superfamily
DN067_RS11175	COG1024	Enoyl-CoA hydratase
DN067_RS11190	COG1960	acyl-CoA dehydrogenase activity
DN067_RS11195	COG2814	Major facilitator Superfamily
DN067_RS11200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DN067_RS11205	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DN067_RS11220	COG3842	ATPase activity
DN067_RS11225	COG1840	ABC-type Fe3 transport system, periplasmic component
DN067_RS11235	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN067_RS11240	COG1414	Transcriptional regulator
DN067_RS11250	COG0583	DNA-binding transcription factor activity
DN067_RS11255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DN067_RS11260	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS11270	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DN067_RS11280	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS11285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN067_RS11290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN067_RS11295	COG2267	carboxylic ester hydrolase activity
DN067_RS11315	COG3038	cytochrome b561
DN067_RS11320	COG0753	catalase activity
DN067_RS11360	COG2050	protein possibly involved in aromatic compounds catabolism
DN067_RS11370	COG3327	negative regulation of DNA-templated transcription, initiation
DN067_RS11375	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DN067_RS11380	COG0183	Belongs to the thiolase family
DN067_RS11385	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN067_RS11390	COG1024	Enoyl-CoA hydratase
DN067_RS11395	COG1024	Enoyl-CoA hydratase
DN067_RS11400	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DN067_RS11405	COG2151	metal-sulfur cluster biosynthetic enzyme
DN067_RS11410	COG3396	Phenylacetate-CoA oxygenase
DN067_RS11415	COG3460	Phenylacetate-CoA oxygenase
DN067_RS11420	COG3396	Phenylacetate-CoA oxygenase
DN067_RS11425	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS11425	COG2030	dehydratase
DN067_RS11430	COG1760	l-serine dehydratase
DN067_RS11435	COG0531	amino acid
DN067_RS11440	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS11455	COG0446	pyridine nucleotide-disulphide oxidoreductase
DN067_RS11465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DN067_RS11485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN067_RS11500	COG0789	Transcriptional regulator
DN067_RS11515	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DN067_RS11530	COG2807	transmembrane transport
DN067_RS11535	COG0590	tRNA wobble adenosine to inosine editing
DN067_RS11655	COG1116	anion transmembrane transporter activity
DN067_RS11660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DN067_RS11670	COG0864	Transcriptional regulator
DN067_RS11690	COG2249	NAD(P)H dehydrogenase (quinone) activity
DN067_RS11695	COG0439	Biotin carboxylase
DN067_RS11710	COG1063	alcohol dehydrogenase
DN067_RS11720	COG1309	transcriptional regulator
DN067_RS11745	COG0038	chloride channel
DN067_RS11750	COG4770	biotin carboxylase activity
DN067_RS11770	COG1914	H( )-stimulated, divalent metal cation uptake system
DN067_RS11775	COG0583	DNA-binding transcription factor activity
DN067_RS11830	COG1250	3-hydroxyacyl-CoA dehydrogenase
DN067_RS11850	COG2814	Major facilitator Superfamily
DN067_RS11865	COG1560	Kdo2-lipid A biosynthetic process
DN067_RS11875	COG5006	permease, DMT superfamily
DN067_RS11880	COG1522	sequence-specific DNA binding
DN067_RS11895	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DN067_RS11905	COG4122	O-methyltransferase activity
DN067_RS11935	COG1538	Outer membrane efflux protein
DN067_RS11940	COG1137	ATPase activity
DN067_RS11945	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DN067_RS11955	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DN067_RS11960	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DN067_RS11960	COG0517	IMP dehydrogenase activity
DN067_RS12000	COG2814	Major facilitator Superfamily
DN067_RS12040	COG1278	Cold shock
DN067_RS12045	COG1280	lysine exporter protein (LysE YggA)
DN067_RS12080	COG1570	exodeoxyribonuclease VII activity
DN067_RS12135	COG0583	DNA-binding transcription factor activity
DN067_RS12140	COG4638	Rieske (2fe-2S)
DN067_RS12145	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DN067_RS12150	COG0633	Ferredoxin
DN067_RS12150	COG0543	2 iron, 2 sulfur cluster binding
DN067_RS12155	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS12160	COG3135	benzoate transporter
DN067_RS12165	COG2814	Major facilitator Superfamily
DN067_RS12180	COG1643	Atp-dependent helicase
DN067_RS12185	COG0450	alkyl hydroperoxide reductase
DN067_RS12195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DN067_RS12205	COG3634	alkyl hydroperoxide reductase activity
DN067_RS12225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DN067_RS12230	COG0625	glutathione transferase activity
DN067_RS12240	COG2885	chlorophyll binding
DN067_RS12275	COG0542	response to heat
DN067_RS12290	COG1765	OsmC-like protein
DN067_RS12305	COG0667	Aldo Keto reductase
DN067_RS12320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DN067_RS12330	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DN067_RS12340	COG0527	aspartate kinase activity
DN067_RS12350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DN067_RS12360	COG3038	cytochrome b561
DN067_RS12365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DN067_RS12370	COG2252	PERMEase
DN067_RS12380	COG2072	flavoprotein involved in K transport
DN067_RS12395	COG1741	Belongs to the pirin family
DN067_RS12400	COG1309	transcriptional regulator
DN067_RS12425	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
DN067_RS12475	COG1902	pentaerythritol trinitrate reductase activity
DN067_RS12475	COG0446	pyridine nucleotide-disulphide oxidoreductase
DN067_RS12485	COG4251	negative regulation of phosphorylation
DN067_RS12485	COG5001	Diguanylate cyclase
DN067_RS12485	COG3706	GGDEF domain
DN067_RS12485	COG2203	Gaf domain
DN067_RS12495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DN067_RS12515	COG4172	Belongs to the ABC transporter superfamily
DN067_RS12520	COG4239	(ABC) transporter, permease
DN067_RS12525	COG4174	ABC transporter (Permease)
DN067_RS12535	COG1388	LysM domain
DN067_RS12535	COG0741	lytic transglycosylase activity
DN067_RS12535	COG1388	LysM domain
DN067_RS12535	COG0741	lytic transglycosylase activity
DN067_RS12540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DN067_RS12580	COG0583	DNA-binding transcription factor activity
DN067_RS12585	COG1279	arginine transmembrane transporter activity
DN067_RS12605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN067_RS12610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN067_RS12615	COG0006	proline dipeptidase activity
DN067_RS12650	COG2194	sulfuric ester hydrolase activity
DN067_RS12695	COG0739	heme binding
DN067_RS13025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DN067_RS13050	COG3384	dioxygenase
DN067_RS13060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DN067_RS13065	COG2878	Part of a membrane complex involved in electron transport
DN067_RS13070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DN067_RS13095	COG0768	penicillin binding
DN067_RS13100	COG0742	ribosomal rna small subunit methyltransferase
DN067_RS13115	COG0830	nickel cation binding
DN067_RS13125	COG0804	urea catabolic process
DN067_RS13165	COG1253	flavin adenine dinucleotide binding
DN067_RS13175	COG2851	Citrate transporter
DN067_RS13230	COG1773	rubredoxin
DN067_RS13235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DN067_RS13245	COG0583	DNA-binding transcription factor activity
DN067_RS13270	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DN067_RS13275	COG4181	ATPase activity
DN067_RS13320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DN067_RS13340	COG0306	phosphate transporter
DN067_RS13350	COG3958	Transketolase
DN067_RS13355	COG3959	Transketolase, thiamine diphosphate binding domain
DN067_RS13360	COG2271	Major facilitator Superfamily
DN067_RS13365	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS13370	COG0583	DNA-binding transcription factor activity
DN067_RS13390	COG2223	nitrite transmembrane transporter activity
DN067_RS13395	COG2207	Transcriptional regulator
DN067_RS13400	COG2066	Belongs to the glutaminase family
DN067_RS13405	COG0242	peptide deformylase activity
DN067_RS13410	COG0477	Major facilitator Superfamily
DN067_RS13420	COG0028	Belongs to the TPP enzyme family
DN067_RS13435	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS13440	COG2267	carboxylic ester hydrolase activity
DN067_RS13450	COG2271	Major facilitator Superfamily
DN067_RS13455	COG0446	pyridine nucleotide-disulphide oxidoreductase
DN067_RS13465	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS13485	COG1414	Transcriptional regulator
DN067_RS13500	COG1024	Enoyl-CoA hydratase
DN067_RS13510	COG1215	transferase activity, transferring glycosyl groups
DN067_RS13515	COG0726	polysaccharide deacetylase
DN067_RS13515	COG1649	PFAM Uncharacterised BCR, COG1649
DN067_RS13525	COG4681	YaeQ
DN067_RS13535	COG0523	cobalamin synthesis protein
DN067_RS13545	COG1607	acyl-coa hydrolase
DN067_RS13555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN067_RS13560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DN067_RS13565	COG1309	transcriptional regulator
DN067_RS13590	COG2040	homocysteine
DN067_RS13595	COG0531	amino acid
DN067_RS13650	COG1595	DNA-templated transcription, initiation
DN067_RS13660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN067_RS13665	COG0477	Major facilitator Superfamily
DN067_RS13685	COG0084	hydrolase, TatD family'
DN067_RS13775	COG0582	viral genome integration into host DNA
DN067_RS13870	COG0592	DNA-directed DNA polymerase activity
DN067_RS13910	COG2026	Addiction module toxin, RelE StbE family
DN067_RS14050	COG1484	DNA-dependent DNA replication
DN067_RS14140	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DN067_RS14205	COG0405	Gamma-glutamyltransferase
DN067_RS14210	COG2814	Major facilitator Superfamily
DN067_RS14220	COG2050	protein possibly involved in aromatic compounds catabolism
DN067_RS14235	COG1090	epimerase
DN067_RS14255	COG0420	3'-5' exonuclease activity
DN067_RS14280	COG0735	belongs to the Fur family
DN067_RS14285	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DN067_RS14310	COG0121	glutamine amidotransferase
DN067_RS14325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DN067_RS14335	COG0210	DNA helicase
DN067_RS14340	COG2885	chlorophyll binding
DN067_RS14345	COG0204	Acyl-transferase
DN067_RS14360	COG2894	cell division
DN067_RS14380	COG1280	lysine exporter protein (LysE YggA)
DN067_RS14385	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DN067_RS14385	COG1674	ftsk spoiiie
DN067_RS14390	COG0492	ferredoxin-NADP+ reductase activity
DN067_RS14395	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DN067_RS14405	COG0456	acetyltransferase
DN067_RS14450	COG1981	membrane
DN067_RS14465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DN067_RS14465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN067_RS14485	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS14495	COG0657	acetylesterase activity
DN067_RS14505	COG0473	3-isopropylmalate dehydrogenase activity
DN067_RS14510	COG0583	DNA-binding transcription factor activity
DN067_RS14530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DN067_RS14555	COG0564	pseudouridine synthase activity
DN067_RS14565	COG0358	DNA primase activity
DN067_RS14580	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DN067_RS14610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DN067_RS14640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DN067_RS14650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DN067_RS14650	COG0352	thiamine-phosphate diphosphorylase activity
DN067_RS14650	COG0351	phosphomethylpyrimidine kinase
DN067_RS14655	COG1652	LysM domain
DN067_RS14680	COG1399	metal-binding, possibly nucleic acid-binding protein
DN067_RS14685	COG3101	peptidyl-lysine hydroxylation
DN067_RS14690	COG0009	L-threonylcarbamoyladenylate synthase
DN067_RS14695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DN067_RS14700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DN067_RS14715	COG4106	trans-aconitate 2-methyltransferase activity
DN067_RS14730	COG0596	Alpha beta hydrolase
DN067_RS14730	COG2226	methyltransferase
DN067_RS14730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DN067_RS14735	COG1877	trehalose-phosphatase activity
DN067_RS14740	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DN067_RS14745	COG2223	nitrite transmembrane transporter activity
DN067_RS14765	COG1196	nuclear chromosome segregation
DN067_RS14775	COG0730	response to heat
DN067_RS14790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DN067_RS14800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DN067_RS14860	COG0489	protein tyrosine kinase activity
DN067_RS14870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN067_RS14870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN067_RS14900	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DN067_RS14905	COG2081	HI0933 family
DN067_RS14915	COG0668	transmembrane transport
DN067_RS14935	COG0583	DNA-binding transcription factor activity
DN067_RS14955	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DN067_RS14960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DN067_RS14990	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DN067_RS15030	COG0745	RESPONSE REGULATOR receiver
DN067_RS15050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DN067_RS15060	COG2205	protein histidine kinase activity
DN067_RS15130	COG4993	Dehydrogenase
DN067_RS15150	COG0384	phenazine biosynthesis protein PhzF
DN067_RS15180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DN067_RS15195	COG0583	DNA-binding transcription factor activity
DN067_RS15225	COG0583	DNA-binding transcription factor activity
DN067_RS15245	COG0583	DNA-binding transcription factor activity
DN067_RS15260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DN067_RS15265	COG2814	Major facilitator Superfamily
DN067_RS15270	COG1960	acyl-CoA dehydrogenase activity
DN067_RS15275	COG0583	DNA-binding transcription factor activity
DN067_RS15280	COG1063	alcohol dehydrogenase
DN067_RS15310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DN067_RS15315	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DN067_RS15320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN067_RS15335	COG3667	copper resistance
DN067_RS15340	COG2132	Multicopper oxidase
DN067_RS15350	COG0561	phosphatase activity
DN067_RS15355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DN067_RS15380	COG1214	PFAM Peptidase M22, glycoprotease
DN067_RS15435	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DN067_RS15445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DN067_RS15450	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DN067_RS15455	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DN067_RS15515	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DN067_RS15525	COG1846	Transcriptional regulator
DN067_RS15530	COG1764	response to oxidative stress
DN067_RS15580	COG0037	tRNA processing
DN067_RS15590	COG0248	Ppx GppA phosphatase
DN067_RS15620	COG0072	phenylalanine-tRNA ligase activity
DN067_RS15660	COG1238	metal cluster binding
DN067_RS15665	COG0625	glutathione transferase activity
DN067_RS15685	COG0318	PFAM AMP-dependent synthetase and ligase
DN067_RS15690	COG3028	Belongs to the UPF0307 family
DN067_RS15695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DN067_RS15715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DN067_RS15720	COG0617	tRNA 3'-terminal CCA addition
DN067_RS15725	COG1555	photosystem II stabilization
DN067_RS15730	COG3956	TIGRFAM MazG family protein
DN067_RS15740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DN067_RS15760	COG5002	protein histidine kinase activity
DN067_RS15760	COG2205	protein histidine kinase activity
DN067_RS15760	COG0784	Response regulator, receiver
DN067_RS15765	COG1024	Enoyl-CoA hydratase
DN067_RS15770	COG2084	Dehydrogenase
DN067_RS15775	COG3622	Belongs to the hyi family
DN067_RS15805	COG0697	spore germination
DN067_RS15815	COG2814	Major facilitator Superfamily
DN067_RS15840	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DN067_RS15855	COG0084	hydrolase, TatD family'
DN067_RS15870	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DN067_RS15905	COG0440	acetolactate synthase activity
DN067_RS15910	COG0028	Belongs to the TPP enzyme family
DN067_RS15935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DN067_RS15940	COG0577	efflux transmembrane transporter activity
DN067_RS15940	COG1136	(ABC) transporter
DN067_RS15945	COG1538	Outer membrane efflux protein
DN067_RS15960	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DN067_RS15965	COG1162	GTPase activity
DN067_RS15975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DN067_RS15995	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DN067_RS16000	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS16040	COG2986	histidine ammonia-lyase
DN067_RS16055	COG0318	PFAM AMP-dependent synthetase and ligase
DN067_RS16065	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN067_RS16110	COG1426	Protein conserved in bacteria
DN067_RS16145	COG0793	Belongs to the peptidase S41A family
DN067_RS16160	COG2267	carboxylic ester hydrolase activity
DN067_RS16170	COG1012	belongs to the aldehyde dehydrogenase family
DN067_RS16175	COG3265	gluconokinase activity
DN067_RS16185	COG0800	Aldolase
DN067_RS16200	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DN067_RS16205	COG0857	belongs to the CobB CobQ family
DN067_RS16205	COG0280	phosphate acetyltransferase
DN067_RS16210	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DN067_RS16210	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DN067_RS16230	COG0740	serine-type endopeptidase activity
DN067_RS16240	COG4774	siderophore transport
DN067_RS16250	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DN067_RS16260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DN067_RS16260	COG2813	Specifically methylates the guanine in position
DN067_RS16360	COG0788	formyltetrahydrofolate deformylase activity
DN067_RS16385	COG4651	solute:proton antiporter activity
DN067_RS16385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN067_RS16405	COG0724	RNA recognition motif
DN067_RS16410	COG0210	DNA helicase
DN067_RS16435	COG1733	regulation of RNA biosynthetic process
DN067_RS16445	COG2900	Belongs to the SlyX family
DN067_RS16450	COG0488	(ABC) transporter
DN067_RS16455	COG1280	lysine exporter protein (LysE YggA)
DN067_RS16460	COG1560	Kdo2-lipid A biosynthetic process
DN067_RS16470	COG1301	dicarboxylic acid transport
DN067_RS16525	COG0473	3-isopropylmalate dehydrogenase activity
DN067_RS16590	COG0583	DNA-binding transcription factor activity
DN067_RS16600	COG0625	glutathione transferase activity
DN067_RS16605	COG2378	regulation of single-species biofilm formation
DN067_RS16610	COG0546	phosphoglycolate phosphatase activity
DN067_RS16625	COG1530	ribonuclease E activity
DN067_RS16630	COG0318	PFAM AMP-dependent synthetase and ligase
DN067_RS16645	COG0583	DNA-binding transcription factor activity
DN067_RS16650	COG4221	oxidoreductase activity
DN067_RS16655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DN067_RS16665	COG0534	Mate efflux family protein
DN067_RS16680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DN067_RS16720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DN067_RS16725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DN067_RS16740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DN067_RS16750	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DN067_RS16750	COG0644	oxidoreductase
DN067_RS16755	COG0425	Belongs to the sulfur carrier protein TusA family
DN067_RS16760	COG4535	Mg2 and Co2 transporter CorC
DN067_RS16770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DN067_RS16790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DN067_RS16795	COG0475	glutathione-regulated potassium exporter activity
DN067_RS16795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DN067_RS16800	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DN067_RS16810	COG0484	heat shock protein binding
DN067_RS16815	COG0789	Transcriptional regulator
DN067_RS16820	COG0598	Magnesium transport protein CorA
DN067_RS16835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DN067_RS16840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DN067_RS16845	COG1074	ATP-dependent DNA helicase activity
DN067_RS16850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DN067_RS16870	COG2226	methyltransferase
DN067_RS16885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DN067_RS16890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DN067_RS16905	COG2111	Na H antiporter
DN067_RS16905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DN067_RS16910	COG1006	Multisubunit Na H antiporter MnhC subunit
DN067_RS16915	COG0651	ATP synthesis coupled electron transport
DN067_RS16920	COG1863	multisubunit Na H antiporter MnhE subunit
DN067_RS16925	COG2212	antiporter activity
DN067_RS16930	COG1320	monovalent cation:proton antiporter activity
DN067_RS16945	COG0195	Participates in both transcription termination and antitermination
DN067_RS16995	COG0237	dephospho-CoA kinase activity
DN067_RS17005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DN067_RS17020	COG0497	DNA recombination
DN067_RS17030	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DN067_RS17060	COG2169	Transcriptional regulator
DN067_RS17060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DN067_RS17065	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DN067_RS17135	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DN067_RS17150	COG0326	Molecular chaperone. Has ATPase activity
DN067_RS17165	COG2056	Na+-H+ antiporter family
DN067_RS17170	COG0596	Alpha beta hydrolase
DN067_RS17265	COG0546	phosphoglycolate phosphatase activity
DN067_RS17270	COG1716	ATPase activity
DN067_RS17315	COG0181	hydroxymethylbilane synthase activity
DN067_RS17325	COG3275	phosphorelay sensor kinase activity
DN067_RS17345	COG1538	Outer membrane efflux protein
DN067_RS17350	COG0697	spore germination
DN067_RS17375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DN067_RS17380	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DN067_RS17385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DN067_RS17390	COG0772	Belongs to the SEDS family
DN067_RS17415	COG4974	Belongs to the 'phage' integrase family
DN067_RS17420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DN067_RS17430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DN067_RS17440	COG2197	response regulator
DN067_RS17455	COG0793	Belongs to the peptidase S41A family
DN067_RS17460	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DN067_RS17465	COG0795	lipopolysaccharide-transporting ATPase activity
DN067_RS17505	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN067_RS17505	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DN067_RS17515	COG0004	ammonium transporteR
DN067_RS17520	COG0347	Belongs to the P(II) protein family
DN067_RS17530	COG0606	chelatase, subunit chli
DN067_RS17600	COG1061	Type III restriction enzyme res subunit
DN067_RS17615	COG0659	secondary active sulfate transmembrane transporter activity
DN067_RS17620	COG0589	response to stress
DN067_RS17650	COG0606	chelatase, subunit chli
DN067_RS17665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DN067_RS17680	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DN067_RS17695	COG0318	PFAM AMP-dependent synthetase and ligase
DN067_RS17705	COG0477	Major facilitator Superfamily
DN067_RS17710	COG2860	membrane
DN067_RS17720	COG1253	flavin adenine dinucleotide binding
DN067_RS17740	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DN067_RS17775	COG0655	NAD(P)H dehydrogenase (quinone) activity
DN067_RS17785	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DN067_RS17820	COG1309	transcriptional regulator
DN067_RS17855	COG0758	DNA mediated transformation
DN067_RS17865	COG0697	spore germination
DN067_RS17870	COG1309	transcriptional regulator
DN067_RS17885	COG0386	Belongs to the glutathione peroxidase family
DN067_RS17950	COG1121	(ABC) transporter
DN067_RS17955	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DN067_RS17960	COG1280	lysine exporter protein (LysE YggA)
DN067_RS17965	COG2837	iron assimilation
DN067_RS17975	COG0281	malic enzyme
DN067_RS18020	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DN067_RS18020	COG0519	Catalyzes the synthesis of GMP from XMP
DN067_RS18025	COG4399	Belongs to the UPF0754 family
DN067_RS18030	COG2259	Doxx family
DN067_RS18035	COG0586	Pfam SNARE associated Golgi protein
DN067_RS18050	COG1192	Involved in chromosome partitioning
DN067_RS18060	COG0271	Belongs to the BolA IbaG family
DN067_RS18080	COG2267	carboxylic ester hydrolase activity
DN067_RS18100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DN067_RS18100	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DN067_RS18100	COG3321	synthase
DN067_RS18100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DN067_RS18105	COG1960	acyl-CoA dehydrogenase activity
DN067_RS18115	COG2197	response regulator
DN067_RS18125	COG3916	Acyl-homoserine-lactone synthase
DN067_RS18130	COG0477	Major facilitator Superfamily
DN067_RS18135	COG1024	Enoyl-CoA hydratase
DN067_RS18140	COG1024	Enoyl-CoA hydratase
DN067_RS18145	COG1960	acyl-CoA dehydrogenase activity
DN067_RS18150	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DN067_RS18170	COG1113	amino acid transport
DN067_RS18175	COG1113	amino acid transport
DN067_RS18180	COG0251	oxidation-reduction process
DN067_RS18220	COG0564	pseudouridine synthase activity
DN067_RS18285	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DN067_RS18300	COG1802	Transcriptional regulator
DN067_RS18310	COG1448	Aminotransferase
DN067_RS18315	COG0277	FAD linked oxidase domain protein
DN067_RS18325	COG2186	Transcriptional regulator
DN067_RS18335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DN067_RS18340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DN067_RS18355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DN067_RS18360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DN067_RS18415	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DN067_RS18445	COG0728	peptidoglycan biosynthetic process
DN067_RS18450	COG3023	N-Acetylmuramoyl-L-alanine amidase
DN067_RS18510	COG0546	phosphoglycolate phosphatase activity
DN067_RS18515	COG1028	Short-chain dehydrogenase reductase Sdr
DN067_RS18535	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN067_RS18540	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DN067_RS18545	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DN067_RS18550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DN067_RS18555	COG1116	anion transmembrane transporter activity
DN067_RS18560	COG1309	transcriptional regulator
DN067_RS18565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DN067_RS18575	COG0196	riboflavin kinase activity
DN067_RS18580	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DN067_RS18590	COG1047	Peptidyl-prolyl cis-trans
DN067_RS18630	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DN067_RS18635	COG0657	acetylesterase activity
DN067_RS18685	COG2951	lytic endotransglycosylase activity
DN067_RS18690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DN067_RS18710	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DN067_RS18720	COG0671	phosphoesterase, PA-phosphatase related
DN067_RS18725	COG0861	Integral membrane protein TerC family
DN067_RS18735	COG0754	glutathionylspermidine amidase activity
DN067_RS18745	COG0402	S-adenosylhomocysteine deaminase activity
DN067_RS18760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DN067_RS18765	COG1230	cation diffusion facilitator family transporter
DN067_RS18780	COG0706	membrane insertase activity