locus-tag	class	description
KZH52_RS00010	COG0592	DNA-directed DNA polymerase activity
KZH52_RS00020	COG0187	DNA topoisomerase II activity
KZH52_RS00030	COG0586	Pfam SNARE associated Golgi protein
KZH52_RS00035	COG0488	(ABC) transporter
KZH52_RS00060	COG0596	Alpha beta hydrolase
KZH52_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KZH52_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KZH52_RS00110	COG0733	neurotransmitter:sodium symporter activity
KZH52_RS00150	COG2233	PERMEase
KZH52_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZH52_RS00200	COG2814	Major facilitator Superfamily
KZH52_RS00205	COG0656	L-ascorbic acid biosynthetic process
KZH52_RS00210	COG0583	DNA-binding transcription factor activity
KZH52_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZH52_RS00230	COG1064	alcohol dehydrogenase
KZH52_RS00235	COG2818	Glycosylase
KZH52_RS00250	COG1194	a g-specific adenine glycosylase
KZH52_RS00270	COG2983	Belongs to the UPF0260 family
KZH52_RS00275	COG2133	pyrroloquinoline quinone binding
KZH52_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KZH52_RS00285	COG2116	formate transmembrane transporter activity
KZH52_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KZH52_RS00310	COG1335	isochorismatase
KZH52_RS00315	COG0385	Bile acid
KZH52_RS00320	COG0534	Mate efflux family protein
KZH52_RS00325	COG1683	Conserved Protein
KZH52_RS00345	COG0625	glutathione transferase activity
KZH52_RS00355	COG1113	amino acid transport
KZH52_RS00365	COG0523	cobalamin synthesis protein
KZH52_RS00375	COG2188	Transcriptional regulator
KZH52_RS00405	COG0010	Belongs to the arginase family
KZH52_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KZH52_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KZH52_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KZH52_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KZH52_RS00540	COG0534	Mate efflux family protein
KZH52_RS00545	COG0436	Aminotransferase
KZH52_RS00550	COG2733	membrane
KZH52_RS00565	COG2918	glutathione biosynthetic process
KZH52_RS00580	COG0791	NLP P60 protein
KZH52_RS00580	COG1388	LysM domain
KZH52_RS00595	COG3150	esterase
KZH52_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KZH52_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZH52_RS00630	COG2233	PERMEase
KZH52_RS00635	COG2351	hydroxyisourate hydrolase activity
KZH52_RS00670	COG3706	GGDEF domain
KZH52_RS00685	COG1393	Belongs to the ArsC family
KZH52_RS00690	COG0708	Exodeoxyribonuclease III
KZH52_RS00710	COG0189	ligase activity
KZH52_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KZH52_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KZH52_RS00755	COG4942	peptidase
KZH52_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZH52_RS00775	COG2119	membrane
KZH52_RS00780	COG4774	siderophore transport
KZH52_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZH52_RS00785	COG0426	domain, Protein
KZH52_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KZH52_RS00830	COG1902	pentaerythritol trinitrate reductase activity
KZH52_RS00835	COG1519	Transferase
KZH52_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KZH52_RS00845	COG0668	transmembrane transport
KZH52_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZH52_RS00860	COG1335	isochorismatase
KZH52_RS00865	COG1522	sequence-specific DNA binding
KZH52_RS00870	COG3328	transposase activity
KZH52_RS00895	COG2205	protein histidine kinase activity
KZH52_RS00895	COG2198	Histidine kinase
KZH52_RS00895	COG0784	Response regulator, receiver
KZH52_RS00900	COG3162	membrane
KZH52_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZH52_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZH52_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KZH52_RS00940	COG1309	transcriptional regulator
KZH52_RS00960	COG0351	phosphomethylpyrimidine kinase
KZH52_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
KZH52_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KZH52_RS00970	COG2814	Major facilitator Superfamily
KZH52_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KZH52_RS00995	COG1113	amino acid transport
KZH52_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KZH52_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS01020	COG1335	isochorismatase
KZH52_RS01050	COG2814	Major facilitator Superfamily
KZH52_RS01055	COG0583	DNA-binding transcription factor activity
KZH52_RS01075	COG0667	Aldo Keto reductase
KZH52_RS01110	COG1733	regulation of RNA biosynthetic process
KZH52_RS01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZH52_RS01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KZH52_RS01195	COG1002	Type II restriction enzyme, methylase subunits
KZH52_RS01200	COG1061	Type III restriction enzyme res subunit
KZH52_RS01225	COG2329	Antibiotic biosynthesis monooxygenase
KZH52_RS01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KZH52_RS01285	COG0427	acetyl-CoA hydrolase
KZH52_RS01310	COG0659	secondary active sulfate transmembrane transporter activity
KZH52_RS01315	COG4221	oxidoreductase activity
KZH52_RS01320	COG2873	o-acetylhomoserine
KZH52_RS01325	COG0488	(ABC) transporter
KZH52_RS01410	COG0833	amino acid
KZH52_RS01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KZH52_RS01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KZH52_RS01475	COG2226	methyltransferase
KZH52_RS01525	COG0067	glutamate synthase
KZH52_RS01525	COG0069	glutamate synthase activity
KZH52_RS01525	COG0070	glutamate synthase
KZH52_RS01530	COG0493	'glutamate synthase
KZH52_RS01540	COG1704	LemA family
KZH52_RS01545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KZH52_RS01565	COG3307	-O-antigen
KZH52_RS01585	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KZH52_RS01600	COG0194	GDP metabolic process
KZH52_RS01650	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KZH52_RS01670	COG5380	lipid catabolic process
KZH52_RS01675	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KZH52_RS01700	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KZH52_RS01705	COG0277	FAD linked oxidase domain protein
KZH52_RS01715	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KZH52_RS01720	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZH52_RS01735	COG1289	transmembrane transporter activity
KZH52_RS01745	COG0628	permease
KZH52_RS01750	COG1192	Involved in chromosome partitioning
KZH52_RS01780	COG0833	amino acid
KZH52_RS01785	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KZH52_RS01790	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KZH52_RS01800	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS01840	COG0583	DNA-binding transcription factor activity
KZH52_RS01885	COG0517	IMP dehydrogenase activity
KZH52_RS01890	COG1983	PspC domain protein
KZH52_RS01900	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS01915	COG0408	coproporphyrinogen oxidase activity
KZH52_RS01935	COG0513	Belongs to the DEAD box helicase family
KZH52_RS01945	COG1127	ABC transporter
KZH52_RS01950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KZH52_RS01960	COG2854	intermembrane phospholipid transfer
KZH52_RS01970	COG0598	Magnesium transport protein CorA
KZH52_RS01980	COG0494	nUDIX hydrolase
KZH52_RS01985	COG1040	competence protein
KZH52_RS01990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KZH52_RS02010	COG1946	Acyl-CoA thioesterase
KZH52_RS02015	COG1301	dicarboxylic acid transport
KZH52_RS02030	COG1959	2 iron, 2 sulfur cluster binding
KZH52_RS02035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZH52_RS02035	COG1017	nitric oxide dioxygenase activity
KZH52_RS02040	COG0433	COG0433 Predicted ATPase
KZH52_RS02045	COG0626	cystathionine gamma-synthase activity
KZH52_RS02200	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS02205	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KZH52_RS02235	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KZH52_RS02240	COG0339	signal peptide processing
KZH52_RS02245	COG0557	exoribonuclease II activity
KZH52_RS02290	COG0179	Fumarylacetoacetate (FAA) hydrolase
KZH52_RS02295	COG2169	Transcriptional regulator
KZH52_RS02300	COG0697	spore germination
KZH52_RS02305	COG1295	ribonuclease BN
KZH52_RS02340	COG1702	phosphate starvation-inducible protein PhoH
KZH52_RS02350	COG0741	lytic transglycosylase activity
KZH52_RS02350	COG1196	nuclear chromosome segregation
KZH52_RS02350	COG0739	heme binding
KZH52_RS02380	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KZH52_RS02385	COG1183	phosphatidylcholine synthase activity
KZH52_RS02430	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS02435	COG1309	transcriptional regulator
KZH52_RS02450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KZH52_RS02455	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS02475	COG2969	positive regulation of protein catabolic process
KZH52_RS02485	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KZH52_RS02500	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KZH52_RS02505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KZH52_RS02525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KZH52_RS02535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KZH52_RS02540	COG1408	metallophosphoesterase
KZH52_RS02550	COG2199	diguanylate cyclase activity
KZH52_RS02610	COG1607	acyl-coa hydrolase
KZH52_RS02640	COG2350	Protein conserved in bacteria
KZH52_RS02650	COG0613	PHP domain protein
KZH52_RS02655	COG3781	membrane
KZH52_RS02665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KZH52_RS02670	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KZH52_RS02680	COG1862	Preprotein translocase
KZH52_RS02710	COG2205	protein histidine kinase activity
KZH52_RS02715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KZH52_RS02735	COG0726	polysaccharide deacetylase
KZH52_RS02740	COG0463	Glycosyl transferase, family 2
KZH52_RS02745	COG0438	transferase activity, transferring glycosyl groups
KZH52_RS02810	COG0625	glutathione transferase activity
KZH52_RS02815	COG0583	DNA-binding transcription factor activity
KZH52_RS02820	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS02825	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS02835	COG2205	protein histidine kinase activity
KZH52_RS02840	COG0745	RESPONSE REGULATOR receiver
KZH52_RS02845	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KZH52_RS02865	COG2096	Adenosyltransferase
KZH52_RS02915	COG0285	dihydrofolate synthase activity
KZH52_RS02935	COG0450	alkyl hydroperoxide reductase
KZH52_RS02950	COG0477	Major facilitator Superfamily
KZH52_RS02955	COG1272	protein, Hemolysin III
KZH52_RS02985	COG0183	Belongs to the thiolase family
KZH52_RS02990	COG2207	Transcriptional regulator
KZH52_RS03010	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZH52_RS03030	COG0183	Belongs to the thiolase family
KZH52_RS03040	COG2885	chlorophyll binding
KZH52_RS03040	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KZH52_RS03050	COG1690	Belongs to the RtcB family
KZH52_RS03055	COG0833	amino acid
KZH52_RS03065	COG2233	PERMEase
KZH52_RS03070	COG1217	gtp-binding protein TYPA
KZH52_RS03095	COG2094	Belongs to the DNA glycosylase MPG family
KZH52_RS03115	COG1902	pentaerythritol trinitrate reductase activity
KZH52_RS03130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KZH52_RS03135	COG0354	folic acid binding
KZH52_RS03145	COG3189	MarR family transcriptional regulator
KZH52_RS03150	COG2824	Alkylphosphonate utilization operon protein PhnA
KZH52_RS03155	COG3422	double-strand break repair
KZH52_RS03195	COG0840	transmembrane signaling receptor activity
KZH52_RS03215	COG5510	response to toxic substance
KZH52_RS03225	COG2832	Protein of unknown function (DUF454)
KZH52_RS03230	COG1376	ErfK ybiS ycfS ynhG family protein
KZH52_RS03270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KZH52_RS03280	COG1289	transmembrane transporter activity
KZH52_RS03285	COG2814	Major facilitator Superfamily
KZH52_RS03305	COG1115	amino acid carrier protein
KZH52_RS03310	COG1752	Esterase of the alpha-beta hydrolase superfamily
KZH52_RS03315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KZH52_RS03320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KZH52_RS03360	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KZH52_RS03370	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KZH52_RS03375	COG1077	Cell shape determining protein MreB Mrl
KZH52_RS03380	COG1792	Involved in formation and maintenance of cell shape
KZH52_RS03385	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KZH52_RS03390	COG0424	maF-like protein
KZH52_RS03395	COG1530	ribonuclease E activity
KZH52_RS03405	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZH52_RS03415	COG0560	Phosphoserine phosphatase
KZH52_RS03425	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZH52_RS03450	COG2207	Transcriptional regulator
KZH52_RS03470	COG1113	amino acid transport
KZH52_RS03475	COG2828	Protein conserved in bacteria
KZH52_RS03480	COG0142	geranyltranstransferase activity
KZH52_RS03485	COG2315	Protein conserved in bacteria
KZH52_RS03500	COG1752	Esterase of the alpha-beta hydrolase superfamily
KZH52_RS03520	COG2194	sulfuric ester hydrolase activity
KZH52_RS03525	COG0745	RESPONSE REGULATOR receiver
KZH52_RS03530	COG0642	Histidine kinase
KZH52_RS03540	COG0004	ammonium transporteR
KZH52_RS03545	COG0583	DNA-binding transcription factor activity
KZH52_RS03565	COG0525	valine-tRNA ligase activity
KZH52_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS03585	COG0393	Putative heavy-metal-binding
KZH52_RS03590	COG0393	Putative heavy-metal-binding
KZH52_RS03595	COG1538	Outer membrane efflux protein
KZH52_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZH52_RS03610	COG0671	phosphoesterase, PA-phosphatase related
KZH52_RS03640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KZH52_RS03655	COG1648	precorrin-2 dehydrogenase activity
KZH52_RS03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KZH52_RS03660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KZH52_RS03665	COG1733	regulation of RNA biosynthetic process
KZH52_RS03675	COG0531	amino acid
KZH52_RS03690	COG0321	lipoyl(octanoyl) transferase activity
KZH52_RS03695	COG2921	Belongs to the UPF0250 family
KZH52_RS03735	COG2009	succinate dehydrogenase
KZH52_RS03740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KZH52_RS03745	COG1053	succinate dehydrogenase
KZH52_RS03750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KZH52_RS03775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZH52_RS03795	COG2354	Protein conserved in bacteria
KZH52_RS03800	COG2321	neutral zinc metallopeptidase
KZH52_RS03845	COG2843	Capsule synthesis protein
KZH52_RS03860	COG0589	response to stress
KZH52_RS03880	COG0505	Belongs to the CarA family
KZH52_RS03905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KZH52_RS03910	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KZH52_RS03960	COG0477	Major facilitator Superfamily
KZH52_RS03965	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KZH52_RS03980	COG1597	lipid kinase activity
KZH52_RS03985	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KZH52_RS04015	COG0584	glycerophosphoryl diester phosphodiesterase
KZH52_RS04035	COG0741	lytic transglycosylase activity
KZH52_RS04055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KZH52_RS04070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZH52_RS04095	COG0778	Nitroreductase
KZH52_RS04110	COG1929	Belongs to the glycerate kinase type-1 family
KZH52_RS04115	COG0243	molybdopterin cofactor binding
KZH52_RS04120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KZH52_RS04125	COG3339	Conserved Protein
KZH52_RS04150	COG1113	amino acid transport
KZH52_RS04160	COG0019	diaminopimelate decarboxylase activity
KZH52_RS04170	COG1280	lysine exporter protein (LysE YggA)
KZH52_RS04175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KZH52_RS04205	COG0463	Glycosyl transferase, family 2
KZH52_RS04225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZH52_RS04260	COG4591	ABC-type transport system involved in lipoprotein release permease component
KZH52_RS04265	COG1136	(ABC) transporter
KZH52_RS04270	COG0658	competence protein
KZH52_RS04270	COG2333	competence protein COMEC
KZH52_RS04280	COG0616	signal peptide processing
KZH52_RS04280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KZH52_RS04285	COG0596	Alpha beta hydrolase
KZH52_RS04290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KZH52_RS04300	COG0628	permease
KZH52_RS04335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KZH52_RS04355	COG0823	Involved in the tonB-independent uptake of proteins
KZH52_RS04375	COG0824	Thioesterase
KZH52_RS04380	COG1473	amidohydrolase
KZH52_RS04400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KZH52_RS04400	COG0047	phosphoribosylformylglycinamidine synthase activity
KZH52_RS04405	COG2814	Major facilitator Superfamily
KZH52_RS04415	COG1024	Enoyl-CoA hydratase
KZH52_RS04420	COG1056	cytidyltransferase-related domain
KZH52_RS04420	COG1051	belongs to the nudix hydrolase family
KZH52_RS04430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KZH52_RS04445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KZH52_RS04460	COG4625	pathogenesis
KZH52_RS04465	COG0583	DNA-binding transcription factor activity
KZH52_RS04470	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KZH52_RS04475	COG4208	sulfate ABC transporter
KZH52_RS04480	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KZH52_RS04490	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KZH52_RS04495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KZH52_RS04500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KZH52_RS04520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZH52_RS04535	COG0681	Belongs to the peptidase S26 family
KZH52_RS04550	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KZH52_RS04560	COG1381	Involved in DNA repair and RecF pathway recombination
KZH52_RS04565	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KZH52_RS04575	COG4221	oxidoreductase activity
KZH52_RS04605	COG0436	Aminotransferase
KZH52_RS04625	COG0556	nucleotide-excision repair
KZH52_RS04680	COG2070	2-Nitropropane dioxygenase
KZH52_RS04710	COG1215	transferase activity, transferring glycosyl groups
KZH52_RS04725	COG0415	Belongs to the DNA photolyase family
KZH52_RS04735	COG1252	NADH dehydrogenase
KZH52_RS04740	COG1686	Belongs to the peptidase S11 family
KZH52_RS04755	COG1187	pseudouridine synthase activity
KZH52_RS04780	COG0477	Major facilitator Superfamily
KZH52_RS04785	COG0583	DNA-binding transcription factor activity
KZH52_RS04790	COG1823	symporter activity
KZH52_RS04800	COG0612	Peptidase, M16
KZH52_RS04825	COG0352	thiamine-phosphate diphosphorylase activity
KZH52_RS04860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZH52_RS04875	COG1309	transcriptional regulator
KZH52_RS04885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KZH52_RS04890	COG0076	glutamate decarboxylase activity
KZH52_RS04900	COG1522	sequence-specific DNA binding
KZH52_RS04905	COG3961	Belongs to the TPP enzyme family
KZH52_RS04910	COG1113	amino acid transport
KZH52_RS04915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KZH52_RS04920	COG0573	inorganic phosphate transmembrane transporter activity
KZH52_RS04930	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KZH52_RS04935	COG0616	signal peptide processing
KZH52_RS04945	COG3328	transposase activity
KZH52_RS04975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KZH52_RS04980	COG1686	Belongs to the peptidase S11 family
KZH52_RS05005	COG0583	DNA-binding transcription factor activity
KZH52_RS05010	COG1067	ATP-dependent peptidase activity
KZH52_RS05055	COG1966	Carbon starvation protein
KZH52_RS05060	COG2879	small protein
KZH52_RS05090	COG2508	Transcriptional regulator
KZH52_RS05090	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KZH52_RS05110	COG1113	amino acid transport
KZH52_RS05115	COG0583	DNA-binding transcription factor activity
KZH52_RS05120	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZH52_RS05125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZH52_RS05135	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS05140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZH52_RS05145	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KZH52_RS05145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZH52_RS05180	COG2814	Major facilitator Superfamily
KZH52_RS05185	COG4948	Mandelate Racemase Muconate Lactonizing
KZH52_RS05195	COG1309	transcriptional regulator
KZH52_RS05215	COG1741	Belongs to the pirin family
KZH52_RS05225	COG2964	Protein conserved in bacteria
KZH52_RS05240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZH52_RS05245	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZH52_RS05250	COG4605	iron ion homeostasis
KZH52_RS05255	COG4604	ABC transporter, ATP-binding protein
KZH52_RS05260	COG4607	ABC-type enterochelin transport system periplasmic component
KZH52_RS05265	COG4774	siderophore transport
KZH52_RS05275	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KZH52_RS05280	COG1021	2,3-dihydroxybenzoate-AMP ligase
KZH52_RS05285	COG3433	isochorismatase activity
KZH52_RS05285	COG1535	isochorismatase
KZH52_RS05300	COG1132	(ABC) transporter
KZH52_RS05305	COG1132	(ABC) transporter
KZH52_RS05310	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KZH52_RS05320	COG1169	isochorismate synthase
KZH52_RS05335	COG3739	integral membrane protein
KZH52_RS05360	COG0302	gtp cyclohydrolase
KZH52_RS05370	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KZH52_RS05400	COG0308	aminopeptidase N
KZH52_RS05405	COG0512	Glutamine amidotransferase of anthranilate synthase
KZH52_RS05420	COG0174	glutamine synthetase
KZH52_RS05430	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KZH52_RS05465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KZH52_RS05470	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KZH52_RS05475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KZH52_RS05495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KZH52_RS05500	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KZH52_RS05505	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KZH52_RS05520	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS05525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KZH52_RS05530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZH52_RS05540	COG2223	nitrite transmembrane transporter activity
KZH52_RS05550	COG0024	Methionine aminopeptidase
KZH52_RS05555	COG0052	Belongs to the universal ribosomal protein uS2 family
KZH52_RS05570	COG2207	Transcriptional regulator
KZH52_RS05595	COG2951	lytic endotransglycosylase activity
KZH52_RS05600	COG0772	Belongs to the SEDS family
KZH52_RS05615	COG0842	Transport permease protein
KZH52_RS05620	COG1131	(ABC) transporter
KZH52_RS05665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZH52_RS05680	COG4215	(ABC) transporter
KZH52_RS05685	COG4160	amino acid transport
KZH52_RS05690	COG4598	ABC transporter
KZH52_RS05700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KZH52_RS05705	COG0826	peptidase U32
KZH52_RS05710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZH52_RS05725	COG1720	tRNA m6t6A37 methyltransferase activity
KZH52_RS05735	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KZH52_RS05750	COG0642	Histidine kinase
KZH52_RS05760	COG0494	nUDIX hydrolase
KZH52_RS05770	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KZH52_RS05775	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KZH52_RS05780	COG3139	Protein of unknown function (DUF1315)
KZH52_RS05785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KZH52_RS05790	COG1301	dicarboxylic acid transport
KZH52_RS05795	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS05800	COG2819	hydrolase of the alpha beta superfamily
KZH52_RS05810	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KZH52_RS05820	COG2195	Cleaves the N-terminal amino acid of tripeptides
KZH52_RS05825	COG1234	tRNA 3'-trailer cleavage
KZH52_RS05855	COG2363	Small membrane protein
KZH52_RS05875	COG0513	Belongs to the DEAD box helicase family
KZH52_RS05885	COG0778	Nitroreductase
KZH52_RS06230	COG1286	toxin biosynthetic process
KZH52_RS06255	COG4783	chaperone-mediated protein folding
KZH52_RS06260	COG1610	YqeY-like protein
KZH52_RS06360	COG3111	PFAM Bacterial OB fold (BOF) protein
KZH52_RS06385	COG3243	poly(R)-hydroxyalkanoic acid synthase
KZH52_RS06390	COG0786	glutamate:sodium symporter activity
KZH52_RS06400	COG2186	Transcriptional regulator
KZH52_RS06450	COG0477	Major facilitator Superfamily
KZH52_RS06475	COG2985	domain, Protein
KZH52_RS06485	COG2995	paraquat-inducible protein a
KZH52_RS06490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KZH52_RS06490	COG3008	intermembrane lipid transfer
KZH52_RS06520	COG0488	(ABC) transporter
KZH52_RS06525	COG3173	Aminoglycoside phosphotransferase
KZH52_RS06535	COG2433	Pfam Transposase IS66
KZH52_RS06575	COG1301	dicarboxylic acid transport
KZH52_RS06585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZH52_RS06590	COG2011	ABC-type metal ion transport system permease component
KZH52_RS06595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KZH52_RS06600	COG1464	Belongs to the NlpA lipoprotein family
KZH52_RS06605	COG0151	Belongs to the GarS family
KZH52_RS06610	COG0138	bifunctional purine biosynthesis protein purh
KZH52_RS06615	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KZH52_RS06645	COG2308	Evidence 4 Homologs of previously reported genes of
KZH52_RS06655	COG1305	Transglutaminase-like
KZH52_RS06665	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KZH52_RS06670	COG0305	Participates in initiation and elongation during chromosome replication
KZH52_RS06695	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KZH52_RS06705	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KZH52_RS06710	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KZH52_RS06735	COG1649	PFAM Uncharacterised BCR, COG1649
KZH52_RS06735	COG0726	polysaccharide deacetylase
KZH52_RS06740	COG1215	transferase activity, transferring glycosyl groups
KZH52_RS06745	COG3658	cytochrome
KZH52_RS06755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZH52_RS06770	COG0583	DNA-binding transcription factor activity
KZH52_RS06790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZH52_RS06795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZH52_RS06810	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS06815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZH52_RS06820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZH52_RS06845	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KZH52_RS06850	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KZH52_RS06860	COG2205	protein histidine kinase activity
KZH52_RS06865	COG0745	RESPONSE REGULATOR receiver
KZH52_RS06870	COG0174	glutamine synthetase
KZH52_RS06900	COG0729	surface antigen
KZH52_RS06925	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KZH52_RS06930	COG2814	Major facilitator Superfamily
KZH52_RS06945	COG0583	DNA-binding transcription factor activity
KZH52_RS06960	COG1187	pseudouridine synthase activity
KZH52_RS06980	COG0802	atpase or kinase
KZH52_RS06985	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KZH52_RS06995	COG1923	regulation of RNA biosynthetic process
KZH52_RS07000	COG0697	spore germination
KZH52_RS07015	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KZH52_RS07025	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KZH52_RS07030	COG0519	Catalyzes the synthesis of GMP from XMP
KZH52_RS07030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KZH52_RS07035	COG4302	ethanolamine ammonia-lyase activity
KZH52_RS07040	COG4303	Ethanolamine ammonia lyase large subunit
KZH52_RS07045	COG0531	amino acid
KZH52_RS07065	COG1454	alcohol dehydrogenase
KZH52_RS07070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KZH52_RS07080	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KZH52_RS07100	COG0308	aminopeptidase N
KZH52_RS07130	COG1605	Chorismate mutase
KZH52_RS07145	COG1309	transcriptional regulator
KZH52_RS07155	COG0668	transmembrane transport
KZH52_RS07190	COG4773	Receptor
KZH52_RS07210	COG0488	(ABC) transporter
KZH52_RS07215	COG0589	response to stress
KZH52_RS07250	COG3135	benzoate transporter
KZH52_RS07255	COG1522	sequence-specific DNA binding
KZH52_RS07265	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KZH52_RS07270	COG0583	DNA-binding transcription factor activity
KZH52_RS07280	COG0183	Belongs to the thiolase family
KZH52_RS07290	COG2030	dehydratase
KZH52_RS07295	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KZH52_RS07310	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KZH52_RS07320	COG0824	Thioesterase
KZH52_RS07325	COG1454	alcohol dehydrogenase
KZH52_RS07335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KZH52_RS07355	COG0069	glutamate synthase activity
KZH52_RS07520	COG5410	chromosome segregation
KZH52_RS07640	COG0739	heme binding
KZH52_RS07705	COG2814	Major facilitator Superfamily
KZH52_RS07720	COG0511	ligase activity, forming carbon-carbon bonds
KZH52_RS07740	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZH52_RS07740	COG1116	anion transmembrane transporter activity
KZH52_RS07745	COG0745	RESPONSE REGULATOR receiver
KZH52_RS07755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZH52_RS07755	COG2146	nitrite reductase [NAD(P)H] activity
KZH52_RS07760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZH52_RS07765	COG0243	molybdopterin cofactor binding
KZH52_RS07775	COG0243	molybdopterin cofactor binding
KZH52_RS07780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KZH52_RS07795	COG0315	cyclic pyranopterin monophosphate synthase activity
KZH52_RS07795	COG0521	Mo-molybdopterin cofactor biosynthetic process
KZH52_RS07800	COG0303	'Molybdopterin
KZH52_RS07810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZH52_RS07815	COG0697	spore germination
KZH52_RS07835	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KZH52_RS07840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KZH52_RS07895	COG2204	response regulator
KZH52_RS07900	COG3852	Histidine kinase
KZH52_RS07920	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KZH52_RS07925	COG0575	Belongs to the CDS family
KZH52_RS07960	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KZH52_RS07975	COG2137	regulation of response to DNA damage stimulus
KZH52_RS07985	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KZH52_RS07990	COG1011	Hydrolase
KZH52_RS08015	COG1522	sequence-specific DNA binding
KZH52_RS08025	COG1113	amino acid transport
KZH52_RS08040	COG0659	secondary active sulfate transmembrane transporter activity
KZH52_RS08045	COG2135	peptidase activity
KZH52_RS08060	COG3300	MHYT domain
KZH52_RS08060	COG5001	Diguanylate cyclase
KZH52_RS08080	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZH52_RS08080	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KZH52_RS08080	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KZH52_RS08085	COG1105	Belongs to the carbohydrate kinase PfkB family
KZH52_RS08090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZH52_RS08090	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KZH52_RS08120	COG0024	Methionine aminopeptidase
KZH52_RS08125	COG0583	DNA-binding transcription factor activity
KZH52_RS08135	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KZH52_RS08140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KZH52_RS08145	COG0516	GMP reductase activity
KZH52_RS08145	COG0517	IMP dehydrogenase activity
KZH52_RS08170	COG0552	protein localization to endoplasmic reticulum
KZH52_RS08180	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KZH52_RS08195	COG4890	Cyd operon protein YbgT
KZH52_RS08200	COG1294	oxidase, subunit
KZH52_RS08215	COG1585	Membrane protein implicated in regulation of membrane protease activity
KZH52_RS08225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KZH52_RS08230	COG4774	siderophore transport
KZH52_RS08245	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KZH52_RS08250	COG0569	domain protein
KZH52_RS08255	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KZH52_RS08285	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KZH52_RS08290	COG0542	response to heat
KZH52_RS08315	COG1902	pentaerythritol trinitrate reductase activity
KZH52_RS08315	COG0446	pyridine nucleotide-disulphide oxidoreductase
KZH52_RS08360	COG2323	membrane
KZH52_RS08365	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KZH52_RS08375	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KZH52_RS08380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KZH52_RS08385	COG0183	Belongs to the thiolase family
KZH52_RS08390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KZH52_RS08395	COG0596	Alpha beta hydrolase
KZH52_RS08400	COG2271	Major facilitator Superfamily
KZH52_RS08405	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KZH52_RS08410	COG3485	protocatechuate 3,4-dioxygenase
KZH52_RS08415	COG3485	protocatechuate 3,4-dioxygenase
KZH52_RS08420	COG0710	3-dehydroquinate dehydratase activity
KZH52_RS08425	COG3420	alginic acid biosynthetic process
KZH52_RS08430	COG3659	wide pore channel activity
KZH52_RS08435	COG4993	Dehydrogenase
KZH52_RS08445	COG2391	methyltransferase activity
KZH52_RS08460	COG1414	Transcriptional regulator
KZH52_RS08465	COG0583	DNA-binding transcription factor activity
KZH52_RS08470	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS08495	COG2814	Major facilitator Superfamily
KZH52_RS08505	COG0154	amidase activity
KZH52_RS08525	COG4638	Rieske (2fe-2S)
KZH52_RS08535	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS08545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZH52_RS08555	COG3733	amine oxidase
KZH52_RS08565	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS08575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KZH52_RS08580	COG0183	Belongs to the thiolase family
KZH52_RS08585	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KZH52_RS08590	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KZH52_RS08600	COG4829	muconolactone delta-isomerase
KZH52_RS08605	COG4948	Mandelate Racemase Muconate Lactonizing
KZH52_RS08610	COG0583	DNA-binding transcription factor activity
KZH52_RS08620	COG2186	Transcriptional regulator
KZH52_RS08640	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS08660	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS08665	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS08670	COG3829	transcription factor binding
KZH52_RS08680	COG3162	membrane
KZH52_RS08695	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS08710	COG0753	catalase activity
KZH52_RS08730	COG1846	Transcriptional regulator
KZH52_RS08735	COG1902	pentaerythritol trinitrate reductase activity
KZH52_RS08735	COG0446	pyridine nucleotide-disulphide oxidoreductase
KZH52_RS08745	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KZH52_RS08775	COG1309	transcriptional regulator
KZH52_RS08785	COG1335	isochorismatase
KZH52_RS08790	COG0583	DNA-binding transcription factor activity
KZH52_RS08800	COG0475	glutathione-regulated potassium exporter activity
KZH52_RS08800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KZH52_RS08810	COG1473	amidohydrolase
KZH52_RS08820	COG2831	hemolysin activation secretion protein
KZH52_RS08825	COG3210	domain, Protein
KZH52_RS08855	COG2188	Transcriptional regulator
KZH52_RS08870	COG0583	DNA-binding transcription factor activity
KZH52_RS08900	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KZH52_RS08920	COG1566	PFAM secretion protein HlyD family protein
KZH52_RS08935	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS08940	COG0129	dihydroxy-acid dehydratase activity
KZH52_RS08950	COG0583	DNA-binding transcription factor activity
KZH52_RS08955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KZH52_RS08965	COG2084	Dehydrogenase
KZH52_RS08970	COG2207	Transcriptional regulator
KZH52_RS08985	COG1064	alcohol dehydrogenase
KZH52_RS08995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KZH52_RS09000	COG1120	ATPase activity
KZH52_RS09020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KZH52_RS09135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KZH52_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS09200	COG2207	Transcriptional regulator
KZH52_RS09210	COG2205	protein histidine kinase activity
KZH52_RS09215	COG0745	RESPONSE REGULATOR receiver
KZH52_RS09220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZH52_RS09225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KZH52_RS09230	COG1538	Outer membrane efflux protein
KZH52_RS09240	COG2072	flavoprotein involved in K transport
KZH52_RS09260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZH52_RS09280	COG3539	Fimbrial protein
KZH52_RS09310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KZH52_RS09320	COG0753	catalase activity
KZH52_RS09335	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KZH52_RS09395	COG1535	isochorismatase
KZH52_RS09395	COG3433	isochorismatase activity
KZH52_RS09400	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS09405	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KZH52_RS09410	COG4149	molybdate abc transporter
KZH52_RS09415	COG0725	ABC transporter, periplasmic molybdate-binding protein
KZH52_RS09425	COG4638	Rieske (2fe-2S)
KZH52_RS09430	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KZH52_RS09435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZH52_RS09435	COG0543	2 iron, 2 sulfur cluster binding
KZH52_RS09460	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS09475	COG2207	Transcriptional regulator
KZH52_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS09490	COG2610	gluconate transmembrane transporter activity
KZH52_RS09500	COG0583	DNA-binding transcription factor activity
KZH52_RS09510	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KZH52_RS09515	COG2031	fatty acid transporter
KZH52_RS09520	COG0183	Belongs to the thiolase family
KZH52_RS09525	COG0583	DNA-binding transcription factor activity
KZH52_RS09530	COG0583	DNA-binding transcription factor activity
KZH52_RS09545	COG1027	Aspartate ammonia-lyase
KZH52_RS09555	COG0477	Major facilitator Superfamily
KZH52_RS09575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZH52_RS09580	COG4521	taurine ABC transporter
KZH52_RS09595	COG2188	Transcriptional regulator
KZH52_RS09605	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KZH52_RS09610	COG1733	regulation of RNA biosynthetic process
KZH52_RS09615	COG3708	Transcriptional regulator
KZH52_RS09615	COG2207	Transcriptional regulator
KZH52_RS09630	COG0730	response to heat
KZH52_RS09640	COG3453	Protein conserved in bacteria
KZH52_RS09640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZH52_RS09650	COG3781	membrane
KZH52_RS09655	COG1063	alcohol dehydrogenase
KZH52_RS09665	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KZH52_RS09670	COG0508	dehydrogenase complex catalyzes the overall conversion of
KZH52_RS09675	COG0022	dehydrogenase e1 component
KZH52_RS09680	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KZH52_RS09685	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KZH52_RS09700	COG3706	GGDEF domain
KZH52_RS09715	COG0133	tryptophan synthase activity
KZH52_RS09725	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KZH52_RS09760	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KZH52_RS09785	COG2226	methyltransferase
KZH52_RS09840	COG0842	Transport permease protein
KZH52_RS09845	COG0842	Transport permease protein
KZH52_RS09850	COG1131	(ABC) transporter
KZH52_RS09865	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KZH52_RS09870	COG4773	Receptor
KZH52_RS09890	COG0730	response to heat
KZH52_RS09895	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KZH52_RS09915	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KZH52_RS09930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KZH52_RS09970	COG4264	IucA IucC family
KZH52_RS09975	COG4264	IucA IucC family
KZH52_RS09995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KZH52_RS10010	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS10015	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS10020	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KZH52_RS10025	COG2207	Transcriptional regulator
KZH52_RS10030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KZH52_RS10035	COG0776	regulation of translation
KZH52_RS10060	COG0822	iron-sulfur transferase activity
KZH52_RS10065	COG0316	Belongs to the HesB IscA family
KZH52_RS10095	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KZH52_RS10115	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KZH52_RS10120	COG0702	epimerase
KZH52_RS10155	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KZH52_RS10165	COG0339	signal peptide processing
KZH52_RS10215	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KZH52_RS10220	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KZH52_RS10250	COG0776	regulation of translation
KZH52_RS10315	COG0084	hydrolase, TatD family'
KZH52_RS10335	COG1663	tetraacyldisaccharide 4'-kinase activity
KZH52_RS10340	COG1132	(ABC) transporter
KZH52_RS10350	COG0811	peptide transport
KZH52_RS10355	COG1475	DNA binding
KZH52_RS10360	COG1192	Involved in chromosome partitioning
KZH52_RS10370	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KZH52_RS10385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KZH52_RS10390	COG0191	fructose-bisphosphate aldolase activity
KZH52_RS10410	COG0424	maF-like protein
KZH52_RS10415	COG2850	peptidyl-arginine hydroxylation
KZH52_RS10425	COG0640	Transcriptional regulator
KZH52_RS10440	COG3619	membrane
KZH52_RS10445	COG3122	Protein conserved in bacteria
KZH52_RS10450	COG1132	(ABC) transporter
KZH52_RS10470	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KZH52_RS10475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KZH52_RS10485	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KZH52_RS10485	COG0506	proline dehydrogenase activity
KZH52_RS10485	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KZH52_RS10490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KZH52_RS10505	COG3698	Phosphodiester glycosidase
KZH52_RS10515	COG2353	YceI-like domain
KZH52_RS10525	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KZH52_RS10570	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KZH52_RS10570	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KZH52_RS10595	COG3539	Fimbrial protein
KZH52_RS10600	COG3121	Chaperone
KZH52_RS10625	COG0697	spore germination
KZH52_RS10635	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KZH52_RS10645	COG0583	DNA-binding transcription factor activity
KZH52_RS10665	COG1309	transcriptional regulator
KZH52_RS10680	COG1522	sequence-specific DNA binding
KZH52_RS10690	COG1126	abc transporter atp-binding protein
KZH52_RS10695	COG0765	amino acid transport
KZH52_RS10700	COG0765	amino acid transport
KZH52_RS10730	COG1464	Belongs to the NlpA lipoprotein family
KZH52_RS10740	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KZH52_RS10745	COG2011	ABC-type metal ion transport system permease component
KZH52_RS10750	COG0012	GTP binding
KZH52_RS10775	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KZH52_RS10815	COG0386	Belongs to the glutathione peroxidase family
KZH52_RS10825	COG0436	Aminotransferase
KZH52_RS10865	COG3634	alkyl hydroperoxide reductase activity
KZH52_RS10880	COG0583	DNA-binding transcription factor activity
KZH52_RS10885	COG0798	PFAM Bile acid sodium symporter
KZH52_RS10890	COG0640	Transcriptional regulator
KZH52_RS10905	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KZH52_RS10915	COG0583	DNA-binding transcription factor activity
KZH52_RS10925	COG1953	Uracil, thiamine, allantoin
KZH52_RS10935	COG2175	clavaminate synthase activity
KZH52_RS10940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZH52_RS10945	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KZH52_RS10950	COG4521	taurine ABC transporter
KZH52_RS10960	COG0477	Major facilitator Superfamily
KZH52_RS10980	COG1271	oxidase subunit
KZH52_RS10985	COG1294	oxidase, subunit
KZH52_RS10995	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KZH52_RS11015	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KZH52_RS11035	COG3052	prosthetic group binding
KZH52_RS11040	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KZH52_RS11050	COG2814	Major facilitator Superfamily
KZH52_RS11070	COG1346	cytolysis
KZH52_RS11080	COG0583	DNA-binding transcription factor activity
KZH52_RS11085	COG0625	glutathione transferase activity
KZH52_RS11090	COG0625	glutathione transferase activity
KZH52_RS11095	COG0583	DNA-binding transcription factor activity
KZH52_RS11110	COG1045	serine acetyltransferase
KZH52_RS11115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KZH52_RS11120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KZH52_RS11130	COG1280	lysine exporter protein (LysE YggA)
KZH52_RS11145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZH52_RS11150	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZH52_RS11155	COG1126	abc transporter atp-binding protein
KZH52_RS11160	COG0765	amino acid transport
KZH52_RS11165	COG0765	amino acid transport
KZH52_RS11185	COG0784	Response regulator, receiver
KZH52_RS11185	COG2205	protein histidine kinase activity
KZH52_RS11205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KZH52_RS11225	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS11275	COG0583	DNA-binding transcription factor activity
KZH52_RS11295	COG0318	PFAM AMP-dependent synthetase and ligase
KZH52_RS11300	COG1309	transcriptional regulator
KZH52_RS11305	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS11310	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KZH52_RS11315	COG1024	Enoyl-CoA hydratase
KZH52_RS11320	COG4770	biotin carboxylase activity
KZH52_RS11330	COG0583	DNA-binding transcription factor activity
KZH52_RS11345	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS11355	COG2814	Major facilitator Superfamily
KZH52_RS11365	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KZH52_RS11370	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KZH52_RS11375	COG2814	Major facilitator Superfamily
KZH52_RS11380	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS11385	COG1024	Enoyl-CoA hydratase
KZH52_RS11390	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS11395	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZH52_RS11400	COG0183	Belongs to the thiolase family
KZH52_RS11410	COG2814	Major facilitator Superfamily
KZH52_RS11420	COG1024	Enoyl-CoA hydratase
KZH52_RS11435	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS11440	COG2814	Major facilitator Superfamily
KZH52_RS11445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KZH52_RS11450	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KZH52_RS11465	COG3842	ATPase activity
KZH52_RS11470	COG1840	ABC-type Fe3 transport system, periplasmic component
KZH52_RS11480	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZH52_RS11485	COG1414	Transcriptional regulator
KZH52_RS11495	COG0583	DNA-binding transcription factor activity
KZH52_RS11500	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KZH52_RS11505	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS11515	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KZH52_RS11525	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS11530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZH52_RS11535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZH52_RS11540	COG2267	carboxylic ester hydrolase activity
KZH52_RS11560	COG3038	cytochrome b561
KZH52_RS11565	COG0753	catalase activity
KZH52_RS11595	COG2050	protein possibly involved in aromatic compounds catabolism
KZH52_RS11605	COG3327	negative regulation of DNA-templated transcription, initiation
KZH52_RS11610	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KZH52_RS11615	COG0183	Belongs to the thiolase family
KZH52_RS11620	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZH52_RS11625	COG1024	Enoyl-CoA hydratase
KZH52_RS11630	COG1024	Enoyl-CoA hydratase
KZH52_RS11635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KZH52_RS11640	COG2151	metal-sulfur cluster biosynthetic enzyme
KZH52_RS11645	COG3396	Phenylacetate-CoA oxygenase
KZH52_RS11650	COG3460	Phenylacetate-CoA oxygenase
KZH52_RS11655	COG3396	Phenylacetate-CoA oxygenase
KZH52_RS11660	COG2030	dehydratase
KZH52_RS11660	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS11665	COG1760	l-serine dehydratase
KZH52_RS11670	COG0531	amino acid
KZH52_RS11675	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS11690	COG0446	pyridine nucleotide-disulphide oxidoreductase
KZH52_RS11700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KZH52_RS11720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KZH52_RS11730	COG0789	Transcriptional regulator
KZH52_RS11745	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KZH52_RS11760	COG2807	transmembrane transport
KZH52_RS11765	COG0590	tRNA wobble adenosine to inosine editing
KZH52_RS11880	COG1116	anion transmembrane transporter activity
KZH52_RS11885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KZH52_RS11895	COG0864	Transcriptional regulator
KZH52_RS11915	COG2249	NAD(P)H dehydrogenase (quinone) activity
KZH52_RS11920	COG0439	Biotin carboxylase
KZH52_RS11935	COG1063	alcohol dehydrogenase
KZH52_RS11945	COG1309	transcriptional regulator
KZH52_RS11965	COG0038	chloride channel
KZH52_RS11975	COG4770	biotin carboxylase activity
KZH52_RS11995	COG1914	H( )-stimulated, divalent metal cation uptake system
KZH52_RS12000	COG0583	DNA-binding transcription factor activity
KZH52_RS12050	COG1250	3-hydroxyacyl-CoA dehydrogenase
KZH52_RS12070	COG2814	Major facilitator Superfamily
KZH52_RS12080	COG1560	Kdo2-lipid A biosynthetic process
KZH52_RS12090	COG5006	permease, DMT superfamily
KZH52_RS12095	COG1522	sequence-specific DNA binding
KZH52_RS12110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KZH52_RS12120	COG4122	O-methyltransferase activity
KZH52_RS12150	COG1538	Outer membrane efflux protein
KZH52_RS12155	COG1137	ATPase activity
KZH52_RS12160	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KZH52_RS12170	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KZH52_RS12175	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KZH52_RS12175	COG0517	IMP dehydrogenase activity
KZH52_RS12210	COG2814	Major facilitator Superfamily
KZH52_RS12245	COG1278	Cold shock
KZH52_RS12250	COG1280	lysine exporter protein (LysE YggA)
KZH52_RS12280	COG1570	exodeoxyribonuclease VII activity
KZH52_RS12330	COG0583	DNA-binding transcription factor activity
KZH52_RS12335	COG4638	Rieske (2fe-2S)
KZH52_RS12340	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KZH52_RS12345	COG0543	2 iron, 2 sulfur cluster binding
KZH52_RS12345	COG0633	Ferredoxin
KZH52_RS12350	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS12355	COG3135	benzoate transporter
KZH52_RS12360	COG2814	Major facilitator Superfamily
KZH52_RS12375	COG1643	Atp-dependent helicase
KZH52_RS12380	COG0450	alkyl hydroperoxide reductase
KZH52_RS12390	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KZH52_RS12400	COG3634	alkyl hydroperoxide reductase activity
KZH52_RS12420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KZH52_RS12425	COG0625	glutathione transferase activity
KZH52_RS12435	COG2885	chlorophyll binding
KZH52_RS12470	COG0542	response to heat
KZH52_RS12485	COG1765	OsmC-like protein
KZH52_RS12505	COG0667	Aldo Keto reductase
KZH52_RS12520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KZH52_RS12530	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KZH52_RS12540	COG0527	aspartate kinase activity
KZH52_RS12550	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KZH52_RS12560	COG3038	cytochrome b561
KZH52_RS12565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KZH52_RS12570	COG2252	PERMEase
KZH52_RS12580	COG2072	flavoprotein involved in K transport
KZH52_RS12595	COG1741	Belongs to the pirin family
KZH52_RS12600	COG1309	transcriptional regulator
KZH52_RS12625	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KZH52_RS12670	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KZH52_RS12710	COG0446	pyridine nucleotide-disulphide oxidoreductase
KZH52_RS12710	COG1902	pentaerythritol trinitrate reductase activity
KZH52_RS12720	COG3706	GGDEF domain
KZH52_RS12720	COG5001	Diguanylate cyclase
KZH52_RS12720	COG4251	negative regulation of phosphorylation
KZH52_RS12720	COG2203	Gaf domain
KZH52_RS12730	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KZH52_RS12750	COG4172	Belongs to the ABC transporter superfamily
KZH52_RS12755	COG4239	(ABC) transporter, permease
KZH52_RS12760	COG4174	ABC transporter (Permease)
KZH52_RS12770	COG0741	lytic transglycosylase activity
KZH52_RS12770	COG1388	LysM domain
KZH52_RS12770	COG0741	lytic transglycosylase activity
KZH52_RS12770	COG1388	LysM domain
KZH52_RS12775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KZH52_RS12815	COG0583	DNA-binding transcription factor activity
KZH52_RS12820	COG1279	arginine transmembrane transporter activity
KZH52_RS12840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZH52_RS12845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZH52_RS12850	COG0006	proline dipeptidase activity
KZH52_RS12935	COG0739	heme binding
KZH52_RS13265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KZH52_RS13290	COG3384	dioxygenase
KZH52_RS13300	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KZH52_RS13305	COG2878	Part of a membrane complex involved in electron transport
KZH52_RS13310	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KZH52_RS13335	COG0768	penicillin binding
KZH52_RS13340	COG0742	ribosomal rna small subunit methyltransferase
KZH52_RS13355	COG0830	nickel cation binding
KZH52_RS13365	COG0804	urea catabolic process
KZH52_RS13400	COG1253	flavin adenine dinucleotide binding
KZH52_RS13405	COG2851	Citrate transporter
KZH52_RS13460	COG1773	rubredoxin
KZH52_RS13465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KZH52_RS13475	COG0583	DNA-binding transcription factor activity
KZH52_RS13500	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KZH52_RS13505	COG4181	ATPase activity
KZH52_RS13550	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KZH52_RS13570	COG0306	phosphate transporter
KZH52_RS13580	COG3958	Transketolase
KZH52_RS13585	COG3959	Transketolase, thiamine diphosphate binding domain
KZH52_RS13590	COG2271	Major facilitator Superfamily
KZH52_RS13595	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS13600	COG0583	DNA-binding transcription factor activity
KZH52_RS13615	COG2223	nitrite transmembrane transporter activity
KZH52_RS13620	COG2207	Transcriptional regulator
KZH52_RS13625	COG2066	Belongs to the glutaminase family
KZH52_RS13630	COG0242	peptide deformylase activity
KZH52_RS13635	COG0477	Major facilitator Superfamily
KZH52_RS13645	COG0028	Belongs to the TPP enzyme family
KZH52_RS13660	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS13665	COG2267	carboxylic ester hydrolase activity
KZH52_RS13675	COG2271	Major facilitator Superfamily
KZH52_RS13680	COG0446	pyridine nucleotide-disulphide oxidoreductase
KZH52_RS13690	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS13710	COG1414	Transcriptional regulator
KZH52_RS13725	COG1024	Enoyl-CoA hydratase
KZH52_RS13735	COG1215	transferase activity, transferring glycosyl groups
KZH52_RS13740	COG0726	polysaccharide deacetylase
KZH52_RS13740	COG1649	PFAM Uncharacterised BCR, COG1649
KZH52_RS13750	COG4681	YaeQ
KZH52_RS13760	COG0523	cobalamin synthesis protein
KZH52_RS13770	COG1607	acyl-coa hydrolase
KZH52_RS13780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZH52_RS13785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KZH52_RS13790	COG1309	transcriptional regulator
KZH52_RS13815	COG2040	homocysteine
KZH52_RS13820	COG0531	amino acid
KZH52_RS13875	COG1595	DNA-templated transcription, initiation
KZH52_RS13885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KZH52_RS13890	COG0477	Major facilitator Superfamily
KZH52_RS13910	COG0084	hydrolase, TatD family'
KZH52_RS13945	COG0629	single-stranded DNA binding
KZH52_RS14000	COG0582	viral genome integration into host DNA
KZH52_RS14100	COG0592	DNA-directed DNA polymerase activity
KZH52_RS14140	COG2026	Addiction module toxin, RelE StbE family
KZH52_RS14335	COG1484	DNA-dependent DNA replication
KZH52_RS14425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KZH52_RS14495	COG0405	Gamma-glutamyltransferase
KZH52_RS14500	COG2814	Major facilitator Superfamily
KZH52_RS14510	COG2050	protein possibly involved in aromatic compounds catabolism
KZH52_RS14525	COG1090	epimerase
KZH52_RS14550	COG0420	3'-5' exonuclease activity
KZH52_RS14575	COG0735	belongs to the Fur family
KZH52_RS14580	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KZH52_RS14600	COG0121	glutamine amidotransferase
KZH52_RS14615	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KZH52_RS14625	COG0210	DNA helicase
KZH52_RS14630	COG2885	chlorophyll binding
KZH52_RS14635	COG0204	Acyl-transferase
KZH52_RS14650	COG2894	cell division
KZH52_RS14670	COG1280	lysine exporter protein (LysE YggA)
KZH52_RS14675	COG1674	ftsk spoiiie
KZH52_RS14675	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KZH52_RS14680	COG0492	ferredoxin-NADP+ reductase activity
KZH52_RS14685	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KZH52_RS14695	COG0456	acetyltransferase
KZH52_RS14740	COG1981	membrane
KZH52_RS14755	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KZH52_RS14755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KZH52_RS14775	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS14785	COG0657	acetylesterase activity
KZH52_RS14795	COG0473	3-isopropylmalate dehydrogenase activity
KZH52_RS14800	COG0583	DNA-binding transcription factor activity
KZH52_RS14820	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KZH52_RS14845	COG0564	pseudouridine synthase activity
KZH52_RS14855	COG0358	DNA primase activity
KZH52_RS14870	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KZH52_RS14900	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KZH52_RS14930	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KZH52_RS14940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KZH52_RS14940	COG0352	thiamine-phosphate diphosphorylase activity
KZH52_RS14940	COG0351	phosphomethylpyrimidine kinase
KZH52_RS14945	COG1652	LysM domain
KZH52_RS14970	COG1399	metal-binding, possibly nucleic acid-binding protein
KZH52_RS14975	COG3101	peptidyl-lysine hydroxylation
KZH52_RS14980	COG0009	L-threonylcarbamoyladenylate synthase
KZH52_RS14985	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KZH52_RS14990	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KZH52_RS15005	COG4106	trans-aconitate 2-methyltransferase activity
KZH52_RS15020	COG0596	Alpha beta hydrolase
KZH52_RS15020	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KZH52_RS15020	COG2226	methyltransferase
KZH52_RS15025	COG1877	trehalose-phosphatase activity
KZH52_RS15030	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KZH52_RS15035	COG2223	nitrite transmembrane transporter activity
KZH52_RS15055	COG1196	nuclear chromosome segregation
KZH52_RS15065	COG0730	response to heat
KZH52_RS15080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KZH52_RS15090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KZH52_RS15140	COG0489	protein tyrosine kinase activity
KZH52_RS15150	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZH52_RS15150	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZH52_RS15180	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KZH52_RS15185	COG2081	HI0933 family
KZH52_RS15195	COG0668	transmembrane transport
KZH52_RS15215	COG0583	DNA-binding transcription factor activity
KZH52_RS15235	COG1002	Type II restriction enzyme, methylase subunits
KZH52_RS15240	COG1061	Type III restriction enzyme res subunit
KZH52_RS15265	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KZH52_RS15270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KZH52_RS15300	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KZH52_RS15340	COG0745	RESPONSE REGULATOR receiver
KZH52_RS15360	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KZH52_RS15370	COG2205	protein histidine kinase activity
KZH52_RS15440	COG4993	Dehydrogenase
KZH52_RS15465	COG0384	phenazine biosynthesis protein PhzF
KZH52_RS15485	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KZH52_RS15500	COG0583	DNA-binding transcription factor activity
KZH52_RS15530	COG0583	DNA-binding transcription factor activity
KZH52_RS15545	COG0583	DNA-binding transcription factor activity
KZH52_RS15550	COG1053	succinate dehydrogenase
KZH52_RS15560	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KZH52_RS15565	COG2814	Major facilitator Superfamily
KZH52_RS15570	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS15575	COG0583	DNA-binding transcription factor activity
KZH52_RS15580	COG1063	alcohol dehydrogenase
KZH52_RS15610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KZH52_RS15615	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KZH52_RS15620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KZH52_RS15635	COG3667	copper resistance
KZH52_RS15640	COG2132	Multicopper oxidase
KZH52_RS15650	COG0561	phosphatase activity
KZH52_RS15655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KZH52_RS15680	COG1214	PFAM Peptidase M22, glycoprotease
KZH52_RS15735	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KZH52_RS15745	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KZH52_RS15750	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KZH52_RS15755	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KZH52_RS15815	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KZH52_RS15825	COG1846	Transcriptional regulator
KZH52_RS15830	COG1764	response to oxidative stress
KZH52_RS15880	COG0037	tRNA processing
KZH52_RS15890	COG0248	Ppx GppA phosphatase
KZH52_RS15920	COG0072	phenylalanine-tRNA ligase activity
KZH52_RS15960	COG1238	metal cluster binding
KZH52_RS15965	COG0625	glutathione transferase activity
KZH52_RS15980	COG0318	PFAM AMP-dependent synthetase and ligase
KZH52_RS15985	COG3028	Belongs to the UPF0307 family
KZH52_RS15990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KZH52_RS16010	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KZH52_RS16015	COG0617	tRNA 3'-terminal CCA addition
KZH52_RS16020	COG1555	photosystem II stabilization
KZH52_RS16025	COG3956	TIGRFAM MazG family protein
KZH52_RS16035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KZH52_RS16055	COG0784	Response regulator, receiver
KZH52_RS16055	COG2205	protein histidine kinase activity
KZH52_RS16055	COG5002	protein histidine kinase activity
KZH52_RS16060	COG1024	Enoyl-CoA hydratase
KZH52_RS16065	COG2084	Dehydrogenase
KZH52_RS16070	COG3622	Belongs to the hyi family
KZH52_RS16085	COG2433	Pfam Transposase IS66
KZH52_RS16120	COG0697	spore germination
KZH52_RS16130	COG2814	Major facilitator Superfamily
KZH52_RS16135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KZH52_RS16145	COG0583	DNA-binding transcription factor activity
KZH52_RS16155	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KZH52_RS16170	COG0084	hydrolase, TatD family'
KZH52_RS16185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KZH52_RS16215	COG0440	acetolactate synthase activity
KZH52_RS16220	COG0028	Belongs to the TPP enzyme family
KZH52_RS16245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KZH52_RS16250	COG0577	efflux transmembrane transporter activity
KZH52_RS16250	COG1136	(ABC) transporter
KZH52_RS16255	COG1538	Outer membrane efflux protein
KZH52_RS16270	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KZH52_RS16275	COG1162	GTPase activity
KZH52_RS16285	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KZH52_RS16305	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KZH52_RS16310	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS16350	COG2986	histidine ammonia-lyase
KZH52_RS16365	COG0318	PFAM AMP-dependent synthetase and ligase
KZH52_RS16375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZH52_RS16420	COG1426	Protein conserved in bacteria
KZH52_RS16455	COG0793	Belongs to the peptidase S41A family
KZH52_RS16470	COG2267	carboxylic ester hydrolase activity
KZH52_RS16480	COG1012	belongs to the aldehyde dehydrogenase family
KZH52_RS16485	COG3265	gluconokinase activity
KZH52_RS16495	COG0800	Aldolase
KZH52_RS16510	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KZH52_RS16515	COG0857	belongs to the CobB CobQ family
KZH52_RS16515	COG0280	phosphate acetyltransferase
KZH52_RS16520	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KZH52_RS16520	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KZH52_RS16540	COG0740	serine-type endopeptidase activity
KZH52_RS16550	COG4774	siderophore transport
KZH52_RS16560	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KZH52_RS16570	COG2813	Specifically methylates the guanine in position
KZH52_RS16570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KZH52_RS16670	COG0788	formyltetrahydrofolate deformylase activity
KZH52_RS16695	COG4651	solute:proton antiporter activity
KZH52_RS16695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KZH52_RS16715	COG0724	RNA recognition motif
KZH52_RS16720	COG0210	DNA helicase
KZH52_RS16745	COG1733	regulation of RNA biosynthetic process
KZH52_RS16755	COG2900	Belongs to the SlyX family
KZH52_RS16760	COG0488	(ABC) transporter
KZH52_RS16765	COG1280	lysine exporter protein (LysE YggA)
KZH52_RS16770	COG1560	Kdo2-lipid A biosynthetic process
KZH52_RS16780	COG1301	dicarboxylic acid transport
KZH52_RS16835	COG0473	3-isopropylmalate dehydrogenase activity
KZH52_RS16900	COG0583	DNA-binding transcription factor activity
KZH52_RS16910	COG0625	glutathione transferase activity
KZH52_RS16915	COG2378	regulation of single-species biofilm formation
KZH52_RS16920	COG0546	phosphoglycolate phosphatase activity
KZH52_RS16930	COG1530	ribonuclease E activity
KZH52_RS16935	COG0318	PFAM AMP-dependent synthetase and ligase
KZH52_RS16950	COG0583	DNA-binding transcription factor activity
KZH52_RS16955	COG4221	oxidoreductase activity
KZH52_RS16960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KZH52_RS16970	COG0534	Mate efflux family protein
KZH52_RS16985	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KZH52_RS17025	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KZH52_RS17030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KZH52_RS17045	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KZH52_RS17055	COG0644	oxidoreductase
KZH52_RS17055	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KZH52_RS17060	COG0425	Belongs to the sulfur carrier protein TusA family
KZH52_RS17065	COG4535	Mg2 and Co2 transporter CorC
KZH52_RS17075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KZH52_RS17095	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KZH52_RS17100	COG0475	glutathione-regulated potassium exporter activity
KZH52_RS17100	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KZH52_RS17105	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KZH52_RS17115	COG0484	heat shock protein binding
KZH52_RS17120	COG0789	Transcriptional regulator
KZH52_RS17125	COG0598	Magnesium transport protein CorA
KZH52_RS17140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KZH52_RS17145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KZH52_RS17150	COG1074	ATP-dependent DNA helicase activity
KZH52_RS17155	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KZH52_RS17175	COG2226	methyltransferase
KZH52_RS17190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KZH52_RS17195	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KZH52_RS17210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KZH52_RS17210	COG2111	Na H antiporter
KZH52_RS17215	COG1006	Multisubunit Na H antiporter MnhC subunit
KZH52_RS17220	COG0651	ATP synthesis coupled electron transport
KZH52_RS17225	COG1863	multisubunit Na H antiporter MnhE subunit
KZH52_RS17230	COG2212	antiporter activity
KZH52_RS17235	COG1320	monovalent cation:proton antiporter activity
KZH52_RS17250	COG0195	Participates in both transcription termination and antitermination
KZH52_RS17300	COG0237	dephospho-CoA kinase activity
KZH52_RS17310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KZH52_RS17325	COG0497	DNA recombination
KZH52_RS17335	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KZH52_RS17365	COG2169	Transcriptional regulator
KZH52_RS17365	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KZH52_RS17370	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KZH52_RS17435	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KZH52_RS17450	COG0326	Molecular chaperone. Has ATPase activity
KZH52_RS17465	COG2056	Na+-H+ antiporter family
KZH52_RS17470	COG0596	Alpha beta hydrolase
KZH52_RS17565	COG0546	phosphoglycolate phosphatase activity
KZH52_RS17570	COG1716	ATPase activity
KZH52_RS17615	COG0181	hydroxymethylbilane synthase activity
KZH52_RS17625	COG3275	phosphorelay sensor kinase activity
KZH52_RS17645	COG1538	Outer membrane efflux protein
KZH52_RS17650	COG0697	spore germination
KZH52_RS17675	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KZH52_RS17680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KZH52_RS17685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KZH52_RS17690	COG0772	Belongs to the SEDS family
KZH52_RS17715	COG4974	Belongs to the 'phage' integrase family
KZH52_RS17720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KZH52_RS17730	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KZH52_RS17740	COG2197	response regulator
KZH52_RS17755	COG0793	Belongs to the peptidase S41A family
KZH52_RS17760	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KZH52_RS17765	COG0795	lipopolysaccharide-transporting ATPase activity
KZH52_RS17805	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KZH52_RS17805	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KZH52_RS17815	COG0004	ammonium transporteR
KZH52_RS17820	COG0347	Belongs to the P(II) protein family
KZH52_RS17895	COG1061	Type III restriction enzyme res subunit
KZH52_RS17900	COG1002	Type II restriction enzyme, methylase subunits
KZH52_RS17910	COG0659	secondary active sulfate transmembrane transporter activity
KZH52_RS17915	COG0589	response to stress
KZH52_RS17945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KZH52_RS17990	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KZH52_RS18035	COG1061	Type III restriction enzyme res subunit
KZH52_RS18040	COG1002	Type II restriction enzyme, methylase subunits
KZH52_RS18050	COG0659	secondary active sulfate transmembrane transporter activity
KZH52_RS18055	COG0589	response to stress
KZH52_RS18110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KZH52_RS18125	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KZH52_RS18140	COG0318	PFAM AMP-dependent synthetase and ligase
KZH52_RS18150	COG0477	Major facilitator Superfamily
KZH52_RS18155	COG2860	membrane
KZH52_RS18165	COG1253	flavin adenine dinucleotide binding
KZH52_RS18185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KZH52_RS18230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KZH52_RS18300	COG0758	DNA mediated transformation
KZH52_RS18310	COG0697	spore germination
KZH52_RS18315	COG1309	transcriptional regulator
KZH52_RS18330	COG0386	Belongs to the glutathione peroxidase family
KZH52_RS18395	COG1121	(ABC) transporter
KZH52_RS18400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KZH52_RS18405	COG1280	lysine exporter protein (LysE YggA)
KZH52_RS18410	COG2837	iron assimilation
KZH52_RS18420	COG0281	malic enzyme
KZH52_RS18465	COG0519	Catalyzes the synthesis of GMP from XMP
KZH52_RS18465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KZH52_RS18470	COG4399	Belongs to the UPF0754 family
KZH52_RS18475	COG2259	Doxx family
KZH52_RS18480	COG0586	Pfam SNARE associated Golgi protein
KZH52_RS18495	COG1192	Involved in chromosome partitioning
KZH52_RS18505	COG0271	Belongs to the BolA IbaG family
KZH52_RS18525	COG2267	carboxylic ester hydrolase activity
KZH52_RS18545	COG3321	synthase
KZH52_RS18545	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KZH52_RS18545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KZH52_RS18545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KZH52_RS18550	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS18560	COG2197	response regulator
KZH52_RS18570	COG3916	Acyl-homoserine-lactone synthase
KZH52_RS18575	COG0477	Major facilitator Superfamily
KZH52_RS18580	COG1024	Enoyl-CoA hydratase
KZH52_RS18585	COG1024	Enoyl-CoA hydratase
KZH52_RS18590	COG1960	acyl-CoA dehydrogenase activity
KZH52_RS18595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KZH52_RS18615	COG1113	amino acid transport
KZH52_RS18620	COG1113	amino acid transport
KZH52_RS18625	COG0251	oxidation-reduction process
KZH52_RS18665	COG0564	pseudouridine synthase activity
KZH52_RS18725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KZH52_RS18740	COG1802	Transcriptional regulator
KZH52_RS18750	COG1448	Aminotransferase
KZH52_RS18755	COG0277	FAD linked oxidase domain protein
KZH52_RS18765	COG2186	Transcriptional regulator
KZH52_RS18775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KZH52_RS18780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KZH52_RS18795	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KZH52_RS18800	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KZH52_RS18805	COG1216	Glycosyl transferase, family 2
KZH52_RS18835	COG2089	acid synthase
KZH52_RS18850	COG1083	cytidylyl-transferase
KZH52_RS18855	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KZH52_RS18860	COG1086	Polysaccharide biosynthesis protein
KZH52_RS18865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KZH52_RS18870	COG1596	polysaccharide export
KZH52_RS18895	COG0728	peptidoglycan biosynthetic process
KZH52_RS18900	COG3023	N-Acetylmuramoyl-L-alanine amidase
KZH52_RS18955	COG0546	phosphoglycolate phosphatase activity
KZH52_RS18960	COG1028	Short-chain dehydrogenase reductase Sdr
KZH52_RS18980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZH52_RS18985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KZH52_RS18990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KZH52_RS18995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KZH52_RS19000	COG1116	anion transmembrane transporter activity
KZH52_RS19005	COG1309	transcriptional regulator
KZH52_RS19010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KZH52_RS19020	COG0196	riboflavin kinase activity
KZH52_RS19025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KZH52_RS19035	COG1047	Peptidyl-prolyl cis-trans
KZH52_RS19075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KZH52_RS19080	COG0657	acetylesterase activity
KZH52_RS19100	COG0583	DNA-binding transcription factor activity
KZH52_RS19130	COG2951	lytic endotransglycosylase activity
KZH52_RS19135	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KZH52_RS19150	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KZH52_RS19160	COG0671	phosphoesterase, PA-phosphatase related
KZH52_RS19165	COG0861	Integral membrane protein TerC family
KZH52_RS19175	COG0754	glutathionylspermidine amidase activity
KZH52_RS19185	COG0402	S-adenosylhomocysteine deaminase activity
KZH52_RS19200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KZH52_RS19205	COG1230	cation diffusion facilitator family transporter
KZH52_RS19220	COG0706	membrane insertase activity