locus-tag	class	description
H2783_RS00010	COG0592	DNA-directed DNA polymerase activity
H2783_RS00020	COG0187	DNA topoisomerase II activity
H2783_RS00030	COG0586	Pfam SNARE associated Golgi protein
H2783_RS00035	COG0488	(ABC) transporter
H2783_RS00060	COG0596	Alpha beta hydrolase
H2783_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H2783_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H2783_RS00110	COG0733	neurotransmitter:sodium symporter activity
H2783_RS00150	COG2233	PERMEase
H2783_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_RS00200	COG2814	Major facilitator Superfamily
H2783_RS00205	COG0656	L-ascorbic acid biosynthetic process
H2783_RS00210	COG0583	DNA-binding transcription factor activity
H2783_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_RS00230	COG1064	alcohol dehydrogenase
H2783_RS00235	COG2818	Glycosylase
H2783_RS00250	COG1194	a g-specific adenine glycosylase
H2783_RS00270	COG2983	Belongs to the UPF0260 family
H2783_RS00275	COG2133	pyrroloquinoline quinone binding
H2783_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H2783_RS00285	COG2116	formate transmembrane transporter activity
H2783_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2783_RS00310	COG1335	isochorismatase
H2783_RS00315	COG0385	Bile acid
H2783_RS00320	COG0534	Mate efflux family protein
H2783_RS00325	COG1683	Conserved Protein
H2783_RS00345	COG0625	glutathione transferase activity
H2783_RS00355	COG1113	amino acid transport
H2783_RS00365	COG0523	cobalamin synthesis protein
H2783_RS00375	COG2188	Transcriptional regulator
H2783_RS00405	COG0010	Belongs to the arginase family
H2783_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H2783_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H2783_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H2783_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H2783_RS00540	COG0534	Mate efflux family protein
H2783_RS00545	COG0436	Aminotransferase
H2783_RS00550	COG2733	membrane
H2783_RS00565	COG2918	glutathione biosynthetic process
H2783_RS00580	COG1388	LysM domain
H2783_RS00580	COG0791	NLP P60 protein
H2783_RS00595	COG3150	esterase
H2783_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H2783_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_RS00630	COG2233	PERMEase
H2783_RS00635	COG2351	hydroxyisourate hydrolase activity
H2783_RS00670	COG3706	GGDEF domain
H2783_RS00685	COG1393	Belongs to the ArsC family
H2783_RS00690	COG0708	Exodeoxyribonuclease III
H2783_RS00710	COG0189	ligase activity
H2783_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H2783_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H2783_RS00755	COG4942	peptidase
H2783_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2783_RS00775	COG2119	membrane
H2783_RS00780	COG4774	siderophore transport
H2783_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_RS00785	COG0426	domain, Protein
H2783_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H2783_RS00830	COG1902	pentaerythritol trinitrate reductase activity
H2783_RS00835	COG1519	Transferase
H2783_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H2783_RS00845	COG0668	transmembrane transport
H2783_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2783_RS00860	COG1335	isochorismatase
H2783_RS00865	COG1522	sequence-specific DNA binding
H2783_RS00870	COG3328	transposase activity
H2783_RS00895	COG0784	Response regulator, receiver
H2783_RS00895	COG2205	protein histidine kinase activity
H2783_RS00895	COG2198	Histidine kinase
H2783_RS00900	COG3162	membrane
H2783_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2783_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H2783_RS00940	COG1309	transcriptional regulator
H2783_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
H2783_RS00960	COG0351	phosphomethylpyrimidine kinase
H2783_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H2783_RS00970	COG2814	Major facilitator Superfamily
H2783_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H2783_RS00995	COG1113	amino acid transport
H2783_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2783_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS01020	COG1335	isochorismatase
H2783_RS01050	COG2814	Major facilitator Superfamily
H2783_RS01055	COG0583	DNA-binding transcription factor activity
H2783_RS01075	COG0667	Aldo Keto reductase
H2783_RS01110	COG1733	regulation of RNA biosynthetic process
H2783_RS01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2783_RS01120	COG4372	Transposase
H2783_RS01195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H2783_RS01210	COG2329	Antibiotic biosynthesis monooxygenase
H2783_RS01240	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H2783_RS01270	COG0427	acetyl-CoA hydrolase
H2783_RS01295	COG0659	secondary active sulfate transmembrane transporter activity
H2783_RS01300	COG4221	oxidoreductase activity
H2783_RS01305	COG2873	o-acetylhomoserine
H2783_RS01310	COG0488	(ABC) transporter
H2783_RS01395	COG0833	amino acid
H2783_RS01440	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H2783_RS01445	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H2783_RS01460	COG2226	methyltransferase
H2783_RS01510	COG0070	glutamate synthase
H2783_RS01510	COG0069	glutamate synthase activity
H2783_RS01510	COG0067	glutamate synthase
H2783_RS01515	COG0493	'glutamate synthase
H2783_RS01525	COG1704	LemA family
H2783_RS01530	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H2783_RS01545	COG3328	transposase activity
H2783_RS01555	COG3307	-O-antigen
H2783_RS01575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H2783_RS01590	COG0194	GDP metabolic process
H2783_RS01640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H2783_RS01660	COG5380	lipid catabolic process
H2783_RS01665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H2783_RS01690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H2783_RS01695	COG0277	FAD linked oxidase domain protein
H2783_RS01705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H2783_RS01710	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2783_RS01725	COG1289	transmembrane transporter activity
H2783_RS01735	COG0628	permease
H2783_RS01740	COG1192	Involved in chromosome partitioning
H2783_RS01770	COG0833	amino acid
H2783_RS01775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2783_RS01780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H2783_RS01790	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS01830	COG0583	DNA-binding transcription factor activity
H2783_RS01875	COG0517	IMP dehydrogenase activity
H2783_RS01880	COG1983	PspC domain protein
H2783_RS01890	COG1960	acyl-CoA dehydrogenase activity
H2783_RS01905	COG0408	coproporphyrinogen oxidase activity
H2783_RS01925	COG0513	Belongs to the DEAD box helicase family
H2783_RS01935	COG1127	ABC transporter
H2783_RS01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H2783_RS01950	COG2854	intermembrane phospholipid transfer
H2783_RS01960	COG0598	Magnesium transport protein CorA
H2783_RS01970	COG0494	nUDIX hydrolase
H2783_RS01975	COG1040	competence protein
H2783_RS01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H2783_RS02000	COG1946	Acyl-CoA thioesterase
H2783_RS02005	COG1301	dicarboxylic acid transport
H2783_RS02020	COG1959	2 iron, 2 sulfur cluster binding
H2783_RS02025	COG1017	nitric oxide dioxygenase activity
H2783_RS02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2783_RS02030	COG0433	COG0433 Predicted ATPase
H2783_RS02035	COG0626	cystathionine gamma-synthase activity
H2783_RS02190	COG1960	acyl-CoA dehydrogenase activity
H2783_RS02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H2783_RS02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H2783_RS02230	COG0339	signal peptide processing
H2783_RS02235	COG0557	exoribonuclease II activity
H2783_RS02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
H2783_RS02285	COG2169	Transcriptional regulator
H2783_RS02290	COG0697	spore germination
H2783_RS02295	COG1295	ribonuclease BN
H2783_RS02330	COG1702	phosphate starvation-inducible protein PhoH
H2783_RS02340	COG0741	lytic transglycosylase activity
H2783_RS02340	COG0739	heme binding
H2783_RS02340	COG1196	nuclear chromosome segregation
H2783_RS02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H2783_RS02375	COG1183	phosphatidylcholine synthase activity
H2783_RS02420	COG1960	acyl-CoA dehydrogenase activity
H2783_RS02425	COG1309	transcriptional regulator
H2783_RS02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H2783_RS02445	COG1960	acyl-CoA dehydrogenase activity
H2783_RS02465	COG2969	positive regulation of protein catabolic process
H2783_RS02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H2783_RS02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H2783_RS02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H2783_RS02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H2783_RS02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2783_RS02530	COG1408	metallophosphoesterase
H2783_RS02540	COG2199	diguanylate cyclase activity
H2783_RS02600	COG1607	acyl-coa hydrolase
H2783_RS02630	COG2350	Protein conserved in bacteria
H2783_RS02640	COG0613	PHP domain protein
H2783_RS02645	COG3781	membrane
H2783_RS02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H2783_RS02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H2783_RS02670	COG1862	Preprotein translocase
H2783_RS02715	COG2205	protein histidine kinase activity
H2783_RS02720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H2783_RS02740	COG0726	polysaccharide deacetylase
H2783_RS02745	COG0463	Glycosyl transferase, family 2
H2783_RS02750	COG0438	transferase activity, transferring glycosyl groups
H2783_RS02815	COG0625	glutathione transferase activity
H2783_RS02820	COG0583	DNA-binding transcription factor activity
H2783_RS02825	COG1960	acyl-CoA dehydrogenase activity
H2783_RS02830	COG1960	acyl-CoA dehydrogenase activity
H2783_RS02840	COG2205	protein histidine kinase activity
H2783_RS02845	COG0745	RESPONSE REGULATOR receiver
H2783_RS02850	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H2783_RS02870	COG2096	Adenosyltransferase
H2783_RS02920	COG0285	dihydrofolate synthase activity
H2783_RS02940	COG0450	alkyl hydroperoxide reductase
H2783_RS02955	COG0477	Major facilitator Superfamily
H2783_RS02960	COG1272	protein, Hemolysin III
H2783_RS02990	COG0183	Belongs to the thiolase family
H2783_RS02995	COG2207	Transcriptional regulator
H2783_RS03015	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_RS03035	COG0183	Belongs to the thiolase family
H2783_RS03045	COG2885	chlorophyll binding
H2783_RS03045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H2783_RS03055	COG1690	Belongs to the RtcB family
H2783_RS03060	COG0833	amino acid
H2783_RS03070	COG2233	PERMEase
H2783_RS03075	COG1217	gtp-binding protein TYPA
H2783_RS03100	COG2094	Belongs to the DNA glycosylase MPG family
H2783_RS03105	COG4772	TonB-dependent receptor
H2783_RS03110	COG1902	pentaerythritol trinitrate reductase activity
H2783_RS03125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2783_RS03130	COG0354	folic acid binding
H2783_RS03140	COG3189	MarR family transcriptional regulator
H2783_RS03145	COG2824	Alkylphosphonate utilization operon protein PhnA
H2783_RS03150	COG3422	double-strand break repair
H2783_RS03190	COG0840	transmembrane signaling receptor activity
H2783_RS03210	COG5510	response to toxic substance
H2783_RS03220	COG2832	Protein of unknown function (DUF454)
H2783_RS03225	COG1376	ErfK ybiS ycfS ynhG family protein
H2783_RS03265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H2783_RS03275	COG1289	transmembrane transporter activity
H2783_RS03280	COG2814	Major facilitator Superfamily
H2783_RS03300	COG1115	amino acid carrier protein
H2783_RS03305	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2783_RS03310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H2783_RS03315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H2783_RS03345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H2783_RS03355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H2783_RS03360	COG1077	Cell shape determining protein MreB Mrl
H2783_RS03365	COG1792	Involved in formation and maintenance of cell shape
H2783_RS03370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H2783_RS03375	COG0424	maF-like protein
H2783_RS03380	COG1530	ribonuclease E activity
H2783_RS03390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2783_RS03400	COG0560	Phosphoserine phosphatase
H2783_RS03410	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2783_RS03435	COG2207	Transcriptional regulator
H2783_RS03455	COG1113	amino acid transport
H2783_RS03460	COG2828	Protein conserved in bacteria
H2783_RS03465	COG0142	geranyltranstransferase activity
H2783_RS03470	COG2315	Protein conserved in bacteria
H2783_RS03485	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2783_RS03505	COG2194	sulfuric ester hydrolase activity
H2783_RS03510	COG0745	RESPONSE REGULATOR receiver
H2783_RS03515	COG0642	Histidine kinase
H2783_RS03525	COG0004	ammonium transporteR
H2783_RS03530	COG0583	DNA-binding transcription factor activity
H2783_RS03550	COG0525	valine-tRNA ligase activity
H2783_RS03560	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS03570	COG0393	Putative heavy-metal-binding
H2783_RS03575	COG0393	Putative heavy-metal-binding
H2783_RS03580	COG1538	Outer membrane efflux protein
H2783_RS03590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_RS03595	COG0671	phosphoesterase, PA-phosphatase related
H2783_RS03625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H2783_RS03640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H2783_RS03640	COG1648	precorrin-2 dehydrogenase activity
H2783_RS03645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H2783_RS03650	COG1733	regulation of RNA biosynthetic process
H2783_RS03660	COG0531	amino acid
H2783_RS03675	COG0321	lipoyl(octanoyl) transferase activity
H2783_RS03680	COG2921	Belongs to the UPF0250 family
H2783_RS03720	COG2009	succinate dehydrogenase
H2783_RS03725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H2783_RS03730	COG1053	succinate dehydrogenase
H2783_RS03735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H2783_RS03760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2783_RS03780	COG2354	Protein conserved in bacteria
H2783_RS03785	COG2321	neutral zinc metallopeptidase
H2783_RS03825	COG2843	Capsule synthesis protein
H2783_RS03840	COG0589	response to stress
H2783_RS03860	COG0505	Belongs to the CarA family
H2783_RS03885	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H2783_RS03890	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H2783_RS03940	COG0477	Major facilitator Superfamily
H2783_RS03945	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H2783_RS03960	COG1597	lipid kinase activity
H2783_RS03965	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H2783_RS03990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2783_RS03995	COG0584	glycerophosphoryl diester phosphodiesterase
H2783_RS04015	COG0741	lytic transglycosylase activity
H2783_RS04035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H2783_RS04050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2783_RS04075	COG0778	Nitroreductase
H2783_RS04090	COG1929	Belongs to the glycerate kinase type-1 family
H2783_RS04095	COG0243	molybdopterin cofactor binding
H2783_RS04100	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H2783_RS04105	COG3339	Conserved Protein
H2783_RS04115	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H2783_RS04130	COG1113	amino acid transport
H2783_RS04140	COG0019	diaminopimelate decarboxylase activity
H2783_RS04150	COG1280	lysine exporter protein (LysE YggA)
H2783_RS04155	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H2783_RS04185	COG0463	Glycosyl transferase, family 2
H2783_RS04205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_RS04240	COG4591	ABC-type transport system involved in lipoprotein release permease component
H2783_RS04245	COG1136	(ABC) transporter
H2783_RS04250	COG0658	competence protein
H2783_RS04250	COG2333	competence protein COMEC
H2783_RS04260	COG0616	signal peptide processing
H2783_RS04260	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H2783_RS04265	COG0596	Alpha beta hydrolase
H2783_RS04270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H2783_RS04280	COG0628	permease
H2783_RS04325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2783_RS04345	COG0823	Involved in the tonB-independent uptake of proteins
H2783_RS04365	COG0824	Thioesterase
H2783_RS04370	COG1473	amidohydrolase
H2783_RS04390	COG0047	phosphoribosylformylglycinamidine synthase activity
H2783_RS04390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H2783_RS04395	COG2814	Major facilitator Superfamily
H2783_RS04405	COG1024	Enoyl-CoA hydratase
H2783_RS04410	COG1051	belongs to the nudix hydrolase family
H2783_RS04410	COG1056	cytidyltransferase-related domain
H2783_RS04420	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H2783_RS04435	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H2783_RS04450	COG4625	pathogenesis
H2783_RS04455	COG0583	DNA-binding transcription factor activity
H2783_RS04460	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H2783_RS04465	COG4208	sulfate ABC transporter
H2783_RS04470	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H2783_RS04480	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H2783_RS04485	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H2783_RS04490	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H2783_RS04510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2783_RS04525	COG0681	Belongs to the peptidase S26 family
H2783_RS04540	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H2783_RS04550	COG1381	Involved in DNA repair and RecF pathway recombination
H2783_RS04555	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H2783_RS04565	COG4221	oxidoreductase activity
H2783_RS04595	COG0436	Aminotransferase
H2783_RS04615	COG0556	nucleotide-excision repair
H2783_RS04670	COG2070	2-Nitropropane dioxygenase
H2783_RS04700	COG1215	transferase activity, transferring glycosyl groups
H2783_RS04715	COG0415	Belongs to the DNA photolyase family
H2783_RS04725	COG1252	NADH dehydrogenase
H2783_RS04730	COG1686	Belongs to the peptidase S11 family
H2783_RS04745	COG1187	pseudouridine synthase activity
H2783_RS04770	COG0477	Major facilitator Superfamily
H2783_RS04775	COG0583	DNA-binding transcription factor activity
H2783_RS04780	COG1823	symporter activity
H2783_RS04790	COG0612	Peptidase, M16
H2783_RS04815	COG0352	thiamine-phosphate diphosphorylase activity
H2783_RS04850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2783_RS04865	COG1309	transcriptional regulator
H2783_RS04875	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2783_RS04880	COG0076	glutamate decarboxylase activity
H2783_RS04890	COG1522	sequence-specific DNA binding
H2783_RS04895	COG3961	Belongs to the TPP enzyme family
H2783_RS04900	COG1113	amino acid transport
H2783_RS04905	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H2783_RS04910	COG0573	inorganic phosphate transmembrane transporter activity
H2783_RS04920	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H2783_RS04925	COG0616	signal peptide processing
H2783_RS04960	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H2783_RS04965	COG1686	Belongs to the peptidase S11 family
H2783_RS04990	COG0583	DNA-binding transcription factor activity
H2783_RS04995	COG1067	ATP-dependent peptidase activity
H2783_RS05040	COG1966	Carbon starvation protein
H2783_RS05045	COG2879	small protein
H2783_RS05075	COG2508	Transcriptional regulator
H2783_RS05075	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
H2783_RS05105	COG4372	Transposase
H2783_RS05115	COG1113	amino acid transport
H2783_RS05120	COG0583	DNA-binding transcription factor activity
H2783_RS05125	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_RS05130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_RS05140	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS05145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_RS05150	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2783_RS05150	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
H2783_RS05175	COG4372	Transposase
H2783_RS05205	COG2814	Major facilitator Superfamily
H2783_RS05210	COG4948	Mandelate Racemase Muconate Lactonizing
H2783_RS05220	COG1309	transcriptional regulator
H2783_RS05240	COG1741	Belongs to the pirin family
H2783_RS05250	COG2964	Protein conserved in bacteria
H2783_RS05265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2783_RS05270	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2783_RS05275	COG4605	iron ion homeostasis
H2783_RS05280	COG4604	ABC transporter, ATP-binding protein
H2783_RS05285	COG4607	ABC-type enterochelin transport system periplasmic component
H2783_RS05290	COG4774	siderophore transport
H2783_RS05300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2783_RS05305	COG1021	2,3-dihydroxybenzoate-AMP ligase
H2783_RS05310	COG3433	isochorismatase activity
H2783_RS05310	COG1535	isochorismatase
H2783_RS05325	COG1132	(ABC) transporter
H2783_RS05330	COG1132	(ABC) transporter
H2783_RS05335	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H2783_RS05345	COG1169	isochorismate synthase
H2783_RS05360	COG3739	integral membrane protein
H2783_RS05380	COG0302	gtp cyclohydrolase
H2783_RS05390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H2783_RS05420	COG0308	aminopeptidase N
H2783_RS05425	COG0512	Glutamine amidotransferase of anthranilate synthase
H2783_RS05440	COG0174	glutamine synthetase
H2783_RS05450	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H2783_RS05485	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H2783_RS05490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H2783_RS05495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2783_RS05515	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H2783_RS05520	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H2783_RS05525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H2783_RS05540	COG1960	acyl-CoA dehydrogenase activity
H2783_RS05545	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H2783_RS05550	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2783_RS05560	COG2223	nitrite transmembrane transporter activity
H2783_RS05570	COG0024	Methionine aminopeptidase
H2783_RS05575	COG0052	Belongs to the universal ribosomal protein uS2 family
H2783_RS05590	COG2207	Transcriptional regulator
H2783_RS05615	COG2951	lytic endotransglycosylase activity
H2783_RS05620	COG0772	Belongs to the SEDS family
H2783_RS05635	COG0842	Transport permease protein
H2783_RS05640	COG1131	(ABC) transporter
H2783_RS05685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_RS05700	COG4215	(ABC) transporter
H2783_RS05705	COG4160	amino acid transport
H2783_RS05710	COG4598	ABC transporter
H2783_RS05720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H2783_RS05725	COG0826	peptidase U32
H2783_RS05730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_RS05745	COG1720	tRNA m6t6A37 methyltransferase activity
H2783_RS05755	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H2783_RS05770	COG0642	Histidine kinase
H2783_RS05780	COG0494	nUDIX hydrolase
H2783_RS05790	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H2783_RS05795	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H2783_RS05800	COG3139	Protein of unknown function (DUF1315)
H2783_RS05805	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H2783_RS05810	COG1301	dicarboxylic acid transport
H2783_RS05815	COG1960	acyl-CoA dehydrogenase activity
H2783_RS05820	COG2819	hydrolase of the alpha beta superfamily
H2783_RS05830	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H2783_RS05840	COG2195	Cleaves the N-terminal amino acid of tripeptides
H2783_RS05845	COG1234	tRNA 3'-trailer cleavage
H2783_RS05875	COG2363	Small membrane protein
H2783_RS05895	COG0513	Belongs to the DEAD box helicase family
H2783_RS05905	COG0778	Nitroreductase
H2783_RS05935	COG1286	toxin biosynthetic process
H2783_RS05960	COG4783	chaperone-mediated protein folding
H2783_RS05965	COG1610	YqeY-like protein
H2783_RS06065	COG3111	PFAM Bacterial OB fold (BOF) protein
H2783_RS06090	COG3243	poly(R)-hydroxyalkanoic acid synthase
H2783_RS06095	COG0786	glutamate:sodium symporter activity
H2783_RS06105	COG2186	Transcriptional regulator
H2783_RS06155	COG0477	Major facilitator Superfamily
H2783_RS06180	COG2985	domain, Protein
H2783_RS06190	COG2995	paraquat-inducible protein a
H2783_RS06195	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H2783_RS06195	COG3008	intermembrane lipid transfer
H2783_RS06205	COG1794	racemase activity, acting on amino acids and derivatives
H2783_RS06235	COG1301	dicarboxylic acid transport
H2783_RS06245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2783_RS06250	COG2011	ABC-type metal ion transport system permease component
H2783_RS06255	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H2783_RS06260	COG1464	Belongs to the NlpA lipoprotein family
H2783_RS06265	COG0151	Belongs to the GarS family
H2783_RS06270	COG0138	bifunctional purine biosynthesis protein purh
H2783_RS06275	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H2783_RS06305	COG2308	Evidence 4 Homologs of previously reported genes of
H2783_RS06315	COG1305	Transglutaminase-like
H2783_RS06325	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H2783_RS06330	COG0305	Participates in initiation and elongation during chromosome replication
H2783_RS06355	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H2783_RS06365	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H2783_RS06370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H2783_RS06395	COG0726	polysaccharide deacetylase
H2783_RS06395	COG1649	PFAM Uncharacterised BCR, COG1649
H2783_RS06400	COG1215	transferase activity, transferring glycosyl groups
H2783_RS06405	COG3658	cytochrome
H2783_RS06415	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2783_RS06430	COG0583	DNA-binding transcription factor activity
H2783_RS06450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2783_RS06455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2783_RS06470	COG1960	acyl-CoA dehydrogenase activity
H2783_RS06475	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2783_RS06480	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_RS06505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H2783_RS06510	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H2783_RS06520	COG2205	protein histidine kinase activity
H2783_RS06525	COG0745	RESPONSE REGULATOR receiver
H2783_RS06530	COG0174	glutamine synthetase
H2783_RS06550	COG0729	surface antigen
H2783_RS06575	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2783_RS06580	COG2814	Major facilitator Superfamily
H2783_RS06595	COG0583	DNA-binding transcription factor activity
H2783_RS06610	COG1187	pseudouridine synthase activity
H2783_RS06630	COG0802	atpase or kinase
H2783_RS06635	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H2783_RS06645	COG1923	regulation of RNA biosynthetic process
H2783_RS06650	COG0697	spore germination
H2783_RS06665	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2783_RS06675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H2783_RS06680	COG0519	Catalyzes the synthesis of GMP from XMP
H2783_RS06680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H2783_RS06685	COG4302	ethanolamine ammonia-lyase activity
H2783_RS06690	COG4303	Ethanolamine ammonia lyase large subunit
H2783_RS06695	COG0531	amino acid
H2783_RS06715	COG1454	alcohol dehydrogenase
H2783_RS06720	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2783_RS06730	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H2783_RS06750	COG0308	aminopeptidase N
H2783_RS06760	COG4221	oxidoreductase activity
H2783_RS06770	COG1605	Chorismate mutase
H2783_RS06785	COG1309	transcriptional regulator
H2783_RS06795	COG0668	transmembrane transport
H2783_RS06825	COG4773	Receptor
H2783_RS06845	COG0488	(ABC) transporter
H2783_RS06850	COG0589	response to stress
H2783_RS06875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H2783_RS06885	COG3135	benzoate transporter
H2783_RS06890	COG1522	sequence-specific DNA binding
H2783_RS06900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H2783_RS06905	COG0583	DNA-binding transcription factor activity
H2783_RS06915	COG0183	Belongs to the thiolase family
H2783_RS06925	COG2030	dehydratase
H2783_RS06930	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2783_RS06945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H2783_RS06955	COG0824	Thioesterase
H2783_RS06960	COG1454	alcohol dehydrogenase
H2783_RS06970	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H2783_RS06990	COG0069	glutamate synthase activity
H2783_RS07010	COG2814	Major facilitator Superfamily
H2783_RS07025	COG0511	ligase activity, forming carbon-carbon bonds
H2783_RS07045	COG1116	anion transmembrane transporter activity
H2783_RS07045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2783_RS07050	COG0745	RESPONSE REGULATOR receiver
H2783_RS07060	COG2146	nitrite reductase [NAD(P)H] activity
H2783_RS07060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_RS07065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_RS07070	COG0243	molybdopterin cofactor binding
H2783_RS07080	COG0243	molybdopterin cofactor binding
H2783_RS07085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H2783_RS07100	COG0521	Mo-molybdopterin cofactor biosynthetic process
H2783_RS07100	COG0315	cyclic pyranopterin monophosphate synthase activity
H2783_RS07105	COG0303	'Molybdopterin
H2783_RS07115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_RS07120	COG0697	spore germination
H2783_RS07140	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H2783_RS07145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H2783_RS07200	COG2204	response regulator
H2783_RS07205	COG3852	Histidine kinase
H2783_RS07225	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H2783_RS07230	COG0575	Belongs to the CDS family
H2783_RS07265	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2783_RS07280	COG2137	regulation of response to DNA damage stimulus
H2783_RS07290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H2783_RS07295	COG1011	Hydrolase
H2783_RS07320	COG1522	sequence-specific DNA binding
H2783_RS07330	COG1113	amino acid transport
H2783_RS07345	COG0659	secondary active sulfate transmembrane transporter activity
H2783_RS07350	COG2135	peptidase activity
H2783_RS07365	COG3300	MHYT domain
H2783_RS07365	COG5001	Diguanylate cyclase
H2783_RS07385	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H2783_RS07385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2783_RS07385	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H2783_RS07390	COG1105	Belongs to the carbohydrate kinase PfkB family
H2783_RS07395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H2783_RS07395	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2783_RS07425	COG0024	Methionine aminopeptidase
H2783_RS07430	COG0583	DNA-binding transcription factor activity
H2783_RS07440	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H2783_RS07445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H2783_RS07450	COG0516	GMP reductase activity
H2783_RS07450	COG0517	IMP dehydrogenase activity
H2783_RS07475	COG0552	protein localization to endoplasmic reticulum
H2783_RS07485	COG4372	Transposase
H2783_RS07500	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H2783_RS07515	COG4890	Cyd operon protein YbgT
H2783_RS07520	COG1294	oxidase, subunit
H2783_RS07540	COG1585	Membrane protein implicated in regulation of membrane protease activity
H2783_RS07550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H2783_RS07555	COG4774	siderophore transport
H2783_RS07570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H2783_RS07575	COG0569	domain protein
H2783_RS07580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H2783_RS07610	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H2783_RS07615	COG0542	response to heat
H2783_RS07640	COG1902	pentaerythritol trinitrate reductase activity
H2783_RS07640	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_RS07685	COG2323	membrane
H2783_RS07690	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H2783_RS07700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2783_RS07705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2783_RS07710	COG0183	Belongs to the thiolase family
H2783_RS07715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H2783_RS07720	COG0596	Alpha beta hydrolase
H2783_RS07725	COG2271	Major facilitator Superfamily
H2783_RS07730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H2783_RS07735	COG3485	protocatechuate 3,4-dioxygenase
H2783_RS07740	COG3485	protocatechuate 3,4-dioxygenase
H2783_RS07745	COG0710	3-dehydroquinate dehydratase activity
H2783_RS07750	COG3420	alginic acid biosynthetic process
H2783_RS07755	COG3659	wide pore channel activity
H2783_RS07760	COG4993	Dehydrogenase
H2783_RS07770	COG2391	methyltransferase activity
H2783_RS07785	COG1414	Transcriptional regulator
H2783_RS07790	COG0583	DNA-binding transcription factor activity
H2783_RS07795	COG1960	acyl-CoA dehydrogenase activity
H2783_RS07820	COG2814	Major facilitator Superfamily
H2783_RS07830	COG0154	amidase activity
H2783_RS07850	COG4638	Rieske (2fe-2S)
H2783_RS07860	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS07870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_RS07880	COG3733	amine oxidase
H2783_RS07890	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS07900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2783_RS07905	COG0183	Belongs to the thiolase family
H2783_RS07910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2783_RS07915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2783_RS07925	COG4829	muconolactone delta-isomerase
H2783_RS07930	COG4948	Mandelate Racemase Muconate Lactonizing
H2783_RS07935	COG0583	DNA-binding transcription factor activity
H2783_RS07945	COG2186	Transcriptional regulator
H2783_RS07965	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS07985	COG1960	acyl-CoA dehydrogenase activity
H2783_RS07990	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS07995	COG3829	transcription factor binding
H2783_RS08005	COG3162	membrane
H2783_RS08020	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS08035	COG0753	catalase activity
H2783_RS08055	COG1846	Transcriptional regulator
H2783_RS08060	COG1902	pentaerythritol trinitrate reductase activity
H2783_RS08060	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_RS08070	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H2783_RS08105	COG1309	transcriptional regulator
H2783_RS08115	COG1335	isochorismatase
H2783_RS08120	COG0583	DNA-binding transcription factor activity
H2783_RS08130	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2783_RS08130	COG0475	glutathione-regulated potassium exporter activity
H2783_RS08140	COG1473	amidohydrolase
H2783_RS08150	COG2831	hemolysin activation secretion protein
H2783_RS08155	COG3210	domain, Protein
H2783_RS08185	COG2188	Transcriptional regulator
H2783_RS08200	COG0583	DNA-binding transcription factor activity
H2783_RS08230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H2783_RS08250	COG1566	PFAM secretion protein HlyD family protein
H2783_RS08265	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS08270	COG0129	dihydroxy-acid dehydratase activity
H2783_RS08280	COG0583	DNA-binding transcription factor activity
H2783_RS08285	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H2783_RS08295	COG2084	Dehydrogenase
H2783_RS08300	COG2207	Transcriptional regulator
H2783_RS08315	COG1064	alcohol dehydrogenase
H2783_RS08325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2783_RS08330	COG1120	ATPase activity
H2783_RS08350	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H2783_RS08465	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H2783_RS08515	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS08530	COG2207	Transcriptional regulator
H2783_RS08540	COG2205	protein histidine kinase activity
H2783_RS08545	COG0745	RESPONSE REGULATOR receiver
H2783_RS08550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_RS08555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2783_RS08560	COG1538	Outer membrane efflux protein
H2783_RS08570	COG2072	flavoprotein involved in K transport
H2783_RS08590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2783_RS08610	COG3539	Fimbrial protein
H2783_RS08640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H2783_RS08650	COG0753	catalase activity
H2783_RS08665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2783_RS08725	COG1535	isochorismatase
H2783_RS08725	COG3433	isochorismatase activity
H2783_RS08730	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS08735	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H2783_RS08740	COG4149	molybdate abc transporter
H2783_RS08745	COG0725	ABC transporter, periplasmic molybdate-binding protein
H2783_RS08755	COG4638	Rieske (2fe-2S)
H2783_RS08760	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H2783_RS08765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2783_RS08765	COG0543	2 iron, 2 sulfur cluster binding
H2783_RS08790	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS08805	COG2207	Transcriptional regulator
H2783_RS08810	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS08815	COG2610	gluconate transmembrane transporter activity
H2783_RS08825	COG0583	DNA-binding transcription factor activity
H2783_RS08835	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2783_RS08840	COG2031	fatty acid transporter
H2783_RS08845	COG0183	Belongs to the thiolase family
H2783_RS08850	COG0583	DNA-binding transcription factor activity
H2783_RS08855	COG0583	DNA-binding transcription factor activity
H2783_RS08870	COG1027	Aspartate ammonia-lyase
H2783_RS08880	COG0477	Major facilitator Superfamily
H2783_RS08900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2783_RS08905	COG4521	taurine ABC transporter
H2783_RS08920	COG2188	Transcriptional regulator
H2783_RS08930	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H2783_RS08935	COG1733	regulation of RNA biosynthetic process
H2783_RS08940	COG2207	Transcriptional regulator
H2783_RS08940	COG3708	Transcriptional regulator
H2783_RS08955	COG0730	response to heat
H2783_RS08965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2783_RS08965	COG3453	Protein conserved in bacteria
H2783_RS08975	COG3781	membrane
H2783_RS08980	COG1063	alcohol dehydrogenase
H2783_RS08990	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2783_RS08995	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2783_RS09000	COG0022	dehydrogenase e1 component
H2783_RS09005	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H2783_RS09010	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H2783_RS09025	COG3706	GGDEF domain
H2783_RS09040	COG0133	tryptophan synthase activity
H2783_RS09050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H2783_RS09085	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H2783_RS09110	COG2226	methyltransferase
H2783_RS09165	COG0842	Transport permease protein
H2783_RS09170	COG0842	Transport permease protein
H2783_RS09175	COG1131	(ABC) transporter
H2783_RS09190	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2783_RS09195	COG4773	Receptor
H2783_RS09215	COG0730	response to heat
H2783_RS09220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H2783_RS09240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H2783_RS09255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H2783_RS09295	COG4264	IucA IucC family
H2783_RS09300	COG4264	IucA IucC family
H2783_RS09320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H2783_RS09335	COG1960	acyl-CoA dehydrogenase activity
H2783_RS09340	COG1960	acyl-CoA dehydrogenase activity
H2783_RS09345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2783_RS09350	COG2207	Transcriptional regulator
H2783_RS09355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2783_RS09360	COG0776	regulation of translation
H2783_RS09385	COG0822	iron-sulfur transferase activity
H2783_RS09390	COG0316	Belongs to the HesB IscA family
H2783_RS09420	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H2783_RS09440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H2783_RS09490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H2783_RS09500	COG0339	signal peptide processing
H2783_RS09550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H2783_RS09555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H2783_RS09585	COG0776	regulation of translation
H2783_RS09650	COG0084	hydrolase, TatD family'
H2783_RS09670	COG1663	tetraacyldisaccharide 4'-kinase activity
H2783_RS09675	COG1132	(ABC) transporter
H2783_RS09685	COG0811	peptide transport
H2783_RS09690	COG1475	DNA binding
H2783_RS09695	COG1192	Involved in chromosome partitioning
H2783_RS09705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H2783_RS09720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2783_RS09725	COG0191	fructose-bisphosphate aldolase activity
H2783_RS09745	COG0424	maF-like protein
H2783_RS09750	COG2850	peptidyl-arginine hydroxylation
H2783_RS09760	COG0640	Transcriptional regulator
H2783_RS09770	COG3619	membrane
H2783_RS09775	COG3122	Protein conserved in bacteria
H2783_RS09780	COG1132	(ABC) transporter
H2783_RS09800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H2783_RS09805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2783_RS09815	COG0506	proline dehydrogenase activity
H2783_RS09815	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H2783_RS09815	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H2783_RS09820	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H2783_RS09835	COG3698	Phosphodiester glycosidase
H2783_RS09845	COG2353	YceI-like domain
H2783_RS09855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H2783_RS09900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H2783_RS09900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H2783_RS09925	COG3539	Fimbrial protein
H2783_RS09930	COG3121	Chaperone
H2783_RS09955	COG0697	spore germination
H2783_RS09965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H2783_RS09975	COG0583	DNA-binding transcription factor activity
H2783_RS09995	COG1309	transcriptional regulator
H2783_RS10010	COG1522	sequence-specific DNA binding
H2783_RS10020	COG1126	abc transporter atp-binding protein
H2783_RS10025	COG0765	amino acid transport
H2783_RS10030	COG0765	amino acid transport
H2783_RS10060	COG1464	Belongs to the NlpA lipoprotein family
H2783_RS10070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H2783_RS10075	COG2011	ABC-type metal ion transport system permease component
H2783_RS10080	COG0012	GTP binding
H2783_RS10105	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H2783_RS10145	COG0386	Belongs to the glutathione peroxidase family
H2783_RS10155	COG0436	Aminotransferase
H2783_RS10195	COG3634	alkyl hydroperoxide reductase activity
H2783_RS10210	COG0583	DNA-binding transcription factor activity
H2783_RS10215	COG0798	PFAM Bile acid sodium symporter
H2783_RS10220	COG0640	Transcriptional regulator
H2783_RS10235	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H2783_RS10245	COG0583	DNA-binding transcription factor activity
H2783_RS10255	COG1953	Uracil, thiamine, allantoin
H2783_RS10265	COG2175	clavaminate synthase activity
H2783_RS10270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2783_RS10275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H2783_RS10280	COG4521	taurine ABC transporter
H2783_RS10290	COG0477	Major facilitator Superfamily
H2783_RS10310	COG1271	oxidase subunit
H2783_RS10315	COG1294	oxidase, subunit
H2783_RS10325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_RS10345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H2783_RS10365	COG3052	prosthetic group binding
H2783_RS10370	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H2783_RS10380	COG2814	Major facilitator Superfamily
H2783_RS10400	COG1346	cytolysis
H2783_RS10410	COG0583	DNA-binding transcription factor activity
H2783_RS10415	COG0625	glutathione transferase activity
H2783_RS10420	COG0625	glutathione transferase activity
H2783_RS10425	COG0583	DNA-binding transcription factor activity
H2783_RS10440	COG1045	serine acetyltransferase
H2783_RS10445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2783_RS10450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H2783_RS10460	COG1280	lysine exporter protein (LysE YggA)
H2783_RS10475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2783_RS10480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2783_RS10485	COG1126	abc transporter atp-binding protein
H2783_RS10490	COG0765	amino acid transport
H2783_RS10495	COG0765	amino acid transport
H2783_RS10515	COG0784	Response regulator, receiver
H2783_RS10515	COG2205	protein histidine kinase activity
H2783_RS10535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H2783_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS10605	COG0583	DNA-binding transcription factor activity
H2783_RS10625	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_RS10630	COG1309	transcriptional regulator
H2783_RS10635	COG1960	acyl-CoA dehydrogenase activity
H2783_RS10640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H2783_RS10645	COG1024	Enoyl-CoA hydratase
H2783_RS10650	COG4770	biotin carboxylase activity
H2783_RS10660	COG0583	DNA-binding transcription factor activity
H2783_RS10675	COG1960	acyl-CoA dehydrogenase activity
H2783_RS10685	COG2814	Major facilitator Superfamily
H2783_RS10695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2783_RS10700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2783_RS10705	COG2814	Major facilitator Superfamily
H2783_RS10710	COG1960	acyl-CoA dehydrogenase activity
H2783_RS10715	COG1024	Enoyl-CoA hydratase
H2783_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS10725	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2783_RS10730	COG0183	Belongs to the thiolase family
H2783_RS10740	COG2814	Major facilitator Superfamily
H2783_RS10750	COG1024	Enoyl-CoA hydratase
H2783_RS10765	COG1960	acyl-CoA dehydrogenase activity
H2783_RS10770	COG2814	Major facilitator Superfamily
H2783_RS10775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H2783_RS10780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H2783_RS10795	COG3842	ATPase activity
H2783_RS10800	COG1840	ABC-type Fe3 transport system, periplasmic component
H2783_RS10810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_RS10815	COG1414	Transcriptional regulator
H2783_RS10825	COG0583	DNA-binding transcription factor activity
H2783_RS10830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H2783_RS10835	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS10845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H2783_RS10855	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS10860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2783_RS10865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_RS10870	COG2267	carboxylic ester hydrolase activity
H2783_RS10890	COG3038	cytochrome b561
H2783_RS10895	COG0753	catalase activity
H2783_RS10930	COG2050	protein possibly involved in aromatic compounds catabolism
H2783_RS10940	COG3327	negative regulation of DNA-templated transcription, initiation
H2783_RS10945	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H2783_RS10950	COG0183	Belongs to the thiolase family
H2783_RS10955	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2783_RS10960	COG1024	Enoyl-CoA hydratase
H2783_RS10965	COG1024	Enoyl-CoA hydratase
H2783_RS10970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2783_RS10975	COG2151	metal-sulfur cluster biosynthetic enzyme
H2783_RS10980	COG3396	Phenylacetate-CoA oxygenase
H2783_RS10985	COG3460	Phenylacetate-CoA oxygenase
H2783_RS10990	COG3396	Phenylacetate-CoA oxygenase
H2783_RS10995	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS10995	COG2030	dehydratase
H2783_RS11000	COG1760	l-serine dehydratase
H2783_RS11005	COG0531	amino acid
H2783_RS11010	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS11025	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_RS11035	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H2783_RS11055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2783_RS11065	COG0789	Transcriptional regulator
H2783_RS11075	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H2783_RS11090	COG2807	transmembrane transport
H2783_RS11095	COG0590	tRNA wobble adenosine to inosine editing
H2783_RS11210	COG1116	anion transmembrane transporter activity
H2783_RS11215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2783_RS11225	COG0864	Transcriptional regulator
H2783_RS11245	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2783_RS11250	COG0439	Biotin carboxylase
H2783_RS11265	COG1063	alcohol dehydrogenase
H2783_RS11275	COG1309	transcriptional regulator
H2783_RS11295	COG0038	chloride channel
H2783_RS11300	COG4770	biotin carboxylase activity
H2783_RS11320	COG1914	H( )-stimulated, divalent metal cation uptake system
H2783_RS11325	COG0583	DNA-binding transcription factor activity
H2783_RS11370	COG4372	Transposase
H2783_RS11395	COG1250	3-hydroxyacyl-CoA dehydrogenase
H2783_RS11415	COG2814	Major facilitator Superfamily
H2783_RS11425	COG1560	Kdo2-lipid A biosynthetic process
H2783_RS11435	COG5006	permease, DMT superfamily
H2783_RS11440	COG1522	sequence-specific DNA binding
H2783_RS11455	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H2783_RS11465	COG4122	O-methyltransferase activity
H2783_RS11495	COG1538	Outer membrane efflux protein
H2783_RS11500	COG1137	ATPase activity
H2783_RS11505	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H2783_RS11515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H2783_RS11520	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H2783_RS11520	COG0517	IMP dehydrogenase activity
H2783_RS11555	COG2814	Major facilitator Superfamily
H2783_RS11590	COG1278	Cold shock
H2783_RS11595	COG1280	lysine exporter protein (LysE YggA)
H2783_RS11625	COG1570	exodeoxyribonuclease VII activity
H2783_RS11680	COG0583	DNA-binding transcription factor activity
H2783_RS11685	COG4638	Rieske (2fe-2S)
H2783_RS11690	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H2783_RS11695	COG0543	2 iron, 2 sulfur cluster binding
H2783_RS11695	COG0633	Ferredoxin
H2783_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS11705	COG3135	benzoate transporter
H2783_RS11710	COG2814	Major facilitator Superfamily
H2783_RS11725	COG1643	Atp-dependent helicase
H2783_RS11730	COG0450	alkyl hydroperoxide reductase
H2783_RS11740	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H2783_RS11750	COG3634	alkyl hydroperoxide reductase activity
H2783_RS11770	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H2783_RS11775	COG0625	glutathione transferase activity
H2783_RS11785	COG2885	chlorophyll binding
H2783_RS11820	COG0542	response to heat
H2783_RS11835	COG1765	OsmC-like protein
H2783_RS11855	COG0667	Aldo Keto reductase
H2783_RS11870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H2783_RS11880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H2783_RS11890	COG0527	aspartate kinase activity
H2783_RS11900	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H2783_RS11910	COG3038	cytochrome b561
H2783_RS11915	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H2783_RS11920	COG2252	PERMEase
H2783_RS11930	COG2072	flavoprotein involved in K transport
H2783_RS11945	COG1741	Belongs to the pirin family
H2783_RS11950	COG1309	transcriptional regulator
H2783_RS11960	COG0300	oxidoreductase activity
H2783_RS11975	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H2783_RS12025	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS12045	COG0531	amino acid
H2783_RS12055	COG1113	amino acid transport
H2783_RS12095	COG3209	COG3209 Rhs family protein
H2783_RS12125	COG4269	membrane
H2783_RS12140	COG1902	pentaerythritol trinitrate reductase activity
H2783_RS12140	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_RS12150	COG5001	Diguanylate cyclase
H2783_RS12150	COG4251	negative regulation of phosphorylation
H2783_RS12150	COG3706	GGDEF domain
H2783_RS12150	COG2203	Gaf domain
H2783_RS12160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H2783_RS12180	COG4172	Belongs to the ABC transporter superfamily
H2783_RS12185	COG4239	(ABC) transporter, permease
H2783_RS12190	COG4174	ABC transporter (Permease)
H2783_RS12200	COG1388	LysM domain
H2783_RS12200	COG0741	lytic transglycosylase activity
H2783_RS12200	COG0741	lytic transglycosylase activity
H2783_RS12200	COG1388	LysM domain
H2783_RS12205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H2783_RS12245	COG0583	DNA-binding transcription factor activity
H2783_RS12250	COG1279	arginine transmembrane transporter activity
H2783_RS12270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_RS12275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_RS12280	COG0006	proline dipeptidase activity
H2783_RS12320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H2783_RS12350	COG3384	dioxygenase
H2783_RS12360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2783_RS12365	COG2878	Part of a membrane complex involved in electron transport
H2783_RS12370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H2783_RS12395	COG0768	penicillin binding
H2783_RS12400	COG0742	ribosomal rna small subunit methyltransferase
H2783_RS12415	COG0830	nickel cation binding
H2783_RS12425	COG0804	urea catabolic process
H2783_RS12460	COG1253	flavin adenine dinucleotide binding
H2783_RS12465	COG2851	Citrate transporter
H2783_RS12515	COG1773	rubredoxin
H2783_RS12520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2783_RS12530	COG0583	DNA-binding transcription factor activity
H2783_RS12555	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H2783_RS12560	COG4181	ATPase activity
H2783_RS12605	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H2783_RS12625	COG0306	phosphate transporter
H2783_RS12635	COG3958	Transketolase
H2783_RS12640	COG3959	Transketolase, thiamine diphosphate binding domain
H2783_RS12645	COG2271	Major facilitator Superfamily
H2783_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS12655	COG0583	DNA-binding transcription factor activity
H2783_RS12670	COG2223	nitrite transmembrane transporter activity
H2783_RS12675	COG2207	Transcriptional regulator
H2783_RS12680	COG2066	Belongs to the glutaminase family
H2783_RS12685	COG0242	peptide deformylase activity
H2783_RS12690	COG0477	Major facilitator Superfamily
H2783_RS12700	COG0028	Belongs to the TPP enzyme family
H2783_RS12715	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS12720	COG2267	carboxylic ester hydrolase activity
H2783_RS12730	COG2271	Major facilitator Superfamily
H2783_RS12735	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2783_RS12745	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS12765	COG1414	Transcriptional regulator
H2783_RS12780	COG1024	Enoyl-CoA hydratase
H2783_RS12790	COG1215	transferase activity, transferring glycosyl groups
H2783_RS12795	COG1649	PFAM Uncharacterised BCR, COG1649
H2783_RS12795	COG0726	polysaccharide deacetylase
H2783_RS12805	COG4681	YaeQ
H2783_RS12815	COG0523	cobalamin synthesis protein
H2783_RS12825	COG1607	acyl-coa hydrolase
H2783_RS12835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_RS12840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H2783_RS12845	COG1309	transcriptional regulator
H2783_RS12870	COG2040	homocysteine
H2783_RS12875	COG0531	amino acid
H2783_RS12900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2783_RS12905	COG0477	Major facilitator Superfamily
H2783_RS12960	COG0629	single-stranded DNA binding
H2783_RS13005	COG0582	viral genome integration into host DNA
H2783_RS13015	COG0405	Gamma-glutamyltransferase
H2783_RS13020	COG2814	Major facilitator Superfamily
H2783_RS13030	COG2050	protein possibly involved in aromatic compounds catabolism
H2783_RS13045	COG1090	epimerase
H2783_RS13065	COG0420	3'-5' exonuclease activity
H2783_RS13090	COG0735	belongs to the Fur family
H2783_RS13095	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H2783_RS13115	COG0121	glutamine amidotransferase
H2783_RS13130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2783_RS13140	COG0210	DNA helicase
H2783_RS13145	COG2885	chlorophyll binding
H2783_RS13150	COG0204	Acyl-transferase
H2783_RS13165	COG2894	cell division
H2783_RS13185	COG4372	Transposase
H2783_RS13215	COG1280	lysine exporter protein (LysE YggA)
H2783_RS13220	COG1674	ftsk spoiiie
H2783_RS13220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H2783_RS13225	COG0492	ferredoxin-NADP+ reductase activity
H2783_RS13230	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H2783_RS13240	COG0456	acetyltransferase
H2783_RS13285	COG1981	membrane
H2783_RS13300	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H2783_RS13300	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2783_RS13320	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS13330	COG0657	acetylesterase activity
H2783_RS13340	COG0473	3-isopropylmalate dehydrogenase activity
H2783_RS13345	COG0583	DNA-binding transcription factor activity
H2783_RS13365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H2783_RS13390	COG0564	pseudouridine synthase activity
H2783_RS13400	COG0358	DNA primase activity
H2783_RS13415	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H2783_RS13445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H2783_RS13475	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H2783_RS13485	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H2783_RS13485	COG0352	thiamine-phosphate diphosphorylase activity
H2783_RS13485	COG0351	phosphomethylpyrimidine kinase
H2783_RS13490	COG1652	LysM domain
H2783_RS13515	COG1399	metal-binding, possibly nucleic acid-binding protein
H2783_RS13520	COG3101	peptidyl-lysine hydroxylation
H2783_RS13525	COG0009	L-threonylcarbamoyladenylate synthase
H2783_RS13530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H2783_RS13535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H2783_RS13550	COG4106	trans-aconitate 2-methyltransferase activity
H2783_RS13565	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2783_RS13565	COG2226	methyltransferase
H2783_RS13565	COG0596	Alpha beta hydrolase
H2783_RS13570	COG1877	trehalose-phosphatase activity
H2783_RS13575	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H2783_RS13580	COG2223	nitrite transmembrane transporter activity
H2783_RS13600	COG1196	nuclear chromosome segregation
H2783_RS13610	COG0730	response to heat
H2783_RS13625	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H2783_RS13635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2783_RS13685	COG0489	protein tyrosine kinase activity
H2783_RS13695	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2783_RS13695	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2783_RS13725	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H2783_RS13730	COG2081	HI0933 family
H2783_RS13740	COG0668	transmembrane transport
H2783_RS13760	COG0583	DNA-binding transcription factor activity
H2783_RS13780	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H2783_RS13785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H2783_RS13815	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H2783_RS13855	COG0745	RESPONSE REGULATOR receiver
H2783_RS13875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H2783_RS13885	COG2205	protein histidine kinase activity
H2783_RS13990	COG0384	phenazine biosynthesis protein PhzF
H2783_RS14010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2783_RS14025	COG0583	DNA-binding transcription factor activity
H2783_RS14055	COG0583	DNA-binding transcription factor activity
H2783_RS14070	COG0583	DNA-binding transcription factor activity
H2783_RS14075	COG1053	succinate dehydrogenase
H2783_RS14085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H2783_RS14090	COG2814	Major facilitator Superfamily
H2783_RS14095	COG1960	acyl-CoA dehydrogenase activity
H2783_RS14100	COG0583	DNA-binding transcription factor activity
H2783_RS14105	COG1063	alcohol dehydrogenase
H2783_RS14135	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H2783_RS14140	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H2783_RS14145	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2783_RS14160	COG3667	copper resistance
H2783_RS14165	COG2132	Multicopper oxidase
H2783_RS14175	COG0561	phosphatase activity
H2783_RS14180	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H2783_RS14205	COG1214	PFAM Peptidase M22, glycoprotease
H2783_RS14255	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H2783_RS14265	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H2783_RS14270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H2783_RS14275	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H2783_RS14335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2783_RS14345	COG1846	Transcriptional regulator
H2783_RS14350	COG1764	response to oxidative stress
H2783_RS14390	COG0037	tRNA processing
H2783_RS14400	COG0248	Ppx GppA phosphatase
H2783_RS14430	COG0072	phenylalanine-tRNA ligase activity
H2783_RS14470	COG1238	metal cluster binding
H2783_RS14475	COG0625	glutathione transferase activity
H2783_RS14490	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_RS14495	COG3028	Belongs to the UPF0307 family
H2783_RS14500	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2783_RS14520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H2783_RS14525	COG0617	tRNA 3'-terminal CCA addition
H2783_RS14530	COG1555	photosystem II stabilization
H2783_RS14535	COG3956	TIGRFAM MazG family protein
H2783_RS14545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H2783_RS14565	COG2205	protein histidine kinase activity
H2783_RS14565	COG5002	protein histidine kinase activity
H2783_RS14565	COG0784	Response regulator, receiver
H2783_RS14570	COG1024	Enoyl-CoA hydratase
H2783_RS14575	COG2084	Dehydrogenase
H2783_RS14580	COG3622	Belongs to the hyi family
H2783_RS14610	COG0697	spore germination
H2783_RS14620	COG2814	Major facilitator Superfamily
H2783_RS14625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2783_RS14635	COG0583	DNA-binding transcription factor activity
H2783_RS14645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H2783_RS14660	COG0084	hydrolase, TatD family'
H2783_RS14675	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H2783_RS14705	COG0440	acetolactate synthase activity
H2783_RS14710	COG0028	Belongs to the TPP enzyme family
H2783_RS14735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2783_RS14740	COG0577	efflux transmembrane transporter activity
H2783_RS14740	COG1136	(ABC) transporter
H2783_RS14745	COG1538	Outer membrane efflux protein
H2783_RS14760	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H2783_RS14765	COG1162	GTPase activity
H2783_RS14775	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H2783_RS14795	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H2783_RS14800	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS14840	COG2986	histidine ammonia-lyase
H2783_RS14855	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_RS14870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2783_RS14915	COG1426	Protein conserved in bacteria
H2783_RS14950	COG0793	Belongs to the peptidase S41A family
H2783_RS14965	COG2267	carboxylic ester hydrolase activity
H2783_RS14975	COG1012	belongs to the aldehyde dehydrogenase family
H2783_RS14980	COG3265	gluconokinase activity
H2783_RS14990	COG0800	Aldolase
H2783_RS15000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H2783_RS15005	COG0857	belongs to the CobB CobQ family
H2783_RS15005	COG0280	phosphate acetyltransferase
H2783_RS15010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H2783_RS15010	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H2783_RS15030	COG0740	serine-type endopeptidase activity
H2783_RS15040	COG4774	siderophore transport
H2783_RS15050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H2783_RS15060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2783_RS15060	COG2813	Specifically methylates the guanine in position
H2783_RS15160	COG0788	formyltetrahydrofolate deformylase activity
H2783_RS15185	COG4651	solute:proton antiporter activity
H2783_RS15185	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2783_RS15205	COG0724	RNA recognition motif
H2783_RS15210	COG0210	DNA helicase
H2783_RS15235	COG1733	regulation of RNA biosynthetic process
H2783_RS15245	COG2900	Belongs to the SlyX family
H2783_RS15250	COG0488	(ABC) transporter
H2783_RS15255	COG1280	lysine exporter protein (LysE YggA)
H2783_RS15260	COG1560	Kdo2-lipid A biosynthetic process
H2783_RS15270	COG1301	dicarboxylic acid transport
H2783_RS15325	COG0473	3-isopropylmalate dehydrogenase activity
H2783_RS15390	COG0583	DNA-binding transcription factor activity
H2783_RS15400	COG0625	glutathione transferase activity
H2783_RS15405	COG2378	regulation of single-species biofilm formation
H2783_RS15410	COG0546	phosphoglycolate phosphatase activity
H2783_RS15420	COG1530	ribonuclease E activity
H2783_RS15425	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_RS15440	COG0583	DNA-binding transcription factor activity
H2783_RS15445	COG4221	oxidoreductase activity
H2783_RS15450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H2783_RS15460	COG0534	Mate efflux family protein
H2783_RS15475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H2783_RS15515	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H2783_RS15520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2783_RS15535	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H2783_RS15545	COG0644	oxidoreductase
H2783_RS15545	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H2783_RS15550	COG0425	Belongs to the sulfur carrier protein TusA family
H2783_RS15555	COG4535	Mg2 and Co2 transporter CorC
H2783_RS15565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2783_RS15585	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H2783_RS15590	COG0475	glutathione-regulated potassium exporter activity
H2783_RS15590	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2783_RS15595	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
H2783_RS15605	COG0484	heat shock protein binding
H2783_RS15610	COG0789	Transcriptional regulator
H2783_RS15615	COG0598	Magnesium transport protein CorA
H2783_RS15630	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2783_RS15635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2783_RS15640	COG1074	ATP-dependent DNA helicase activity
H2783_RS15645	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H2783_RS15665	COG2226	methyltransferase
H2783_RS15680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2783_RS15685	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H2783_RS15700	COG2111	Na H antiporter
H2783_RS15700	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H2783_RS15705	COG1006	Multisubunit Na H antiporter MnhC subunit
H2783_RS15710	COG0651	ATP synthesis coupled electron transport
H2783_RS15715	COG1863	multisubunit Na H antiporter MnhE subunit
H2783_RS15720	COG2212	antiporter activity
H2783_RS15725	COG1320	monovalent cation:proton antiporter activity
H2783_RS15740	COG0195	Participates in both transcription termination and antitermination
H2783_RS15790	COG0237	dephospho-CoA kinase activity
H2783_RS15800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2783_RS15815	COG0497	DNA recombination
H2783_RS15825	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H2783_RS15855	COG2169	Transcriptional regulator
H2783_RS15855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2783_RS15860	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H2783_RS15925	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H2783_RS15940	COG0326	Molecular chaperone. Has ATPase activity
H2783_RS15955	COG2056	Na+-H+ antiporter family
H2783_RS15960	COG0596	Alpha beta hydrolase
H2783_RS16055	COG0546	phosphoglycolate phosphatase activity
H2783_RS16060	COG1716	ATPase activity
H2783_RS16105	COG0181	hydroxymethylbilane synthase activity
H2783_RS16115	COG3275	phosphorelay sensor kinase activity
H2783_RS16135	COG1538	Outer membrane efflux protein
H2783_RS16140	COG0697	spore germination
H2783_RS16165	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H2783_RS16170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H2783_RS16175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H2783_RS16180	COG0772	Belongs to the SEDS family
H2783_RS16205	COG4974	Belongs to the 'phage' integrase family
H2783_RS16210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2783_RS16220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H2783_RS16230	COG2197	response regulator
H2783_RS16245	COG0793	Belongs to the peptidase S41A family
H2783_RS16250	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H2783_RS16255	COG0795	lipopolysaccharide-transporting ATPase activity
H2783_RS16295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2783_RS16295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2783_RS16305	COG0004	ammonium transporteR
H2783_RS16310	COG0347	Belongs to the P(II) protein family
H2783_RS16365	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2783_RS16410	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H2783_RS16425	COG1002	Type II restriction enzyme, methylase subunits
H2783_RS16430	COG1061	Type III restriction enzyme res subunit
H2783_RS16470	COG0659	secondary active sulfate transmembrane transporter activity
H2783_RS16475	COG0589	response to stress
H2783_RS16500	COG4372	Transposase
H2783_RS16525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2783_RS16535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2783_RS16550	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H2783_RS16565	COG0318	PFAM AMP-dependent synthetase and ligase
H2783_RS16575	COG0477	Major facilitator Superfamily
H2783_RS16580	COG2860	membrane
H2783_RS16590	COG1253	flavin adenine dinucleotide binding
H2783_RS16610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H2783_RS16645	COG0655	NAD(P)H dehydrogenase (quinone) activity
H2783_RS16655	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H2783_RS16725	COG0758	DNA mediated transformation
H2783_RS16735	COG0697	spore germination
H2783_RS16740	COG1309	transcriptional regulator
H2783_RS16765	COG0386	Belongs to the glutathione peroxidase family
H2783_RS16830	COG1121	(ABC) transporter
H2783_RS16835	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H2783_RS16840	COG1280	lysine exporter protein (LysE YggA)
H2783_RS16845	COG2837	iron assimilation
H2783_RS16855	COG0281	malic enzyme
H2783_RS16900	COG0519	Catalyzes the synthesis of GMP from XMP
H2783_RS16900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H2783_RS16905	COG4399	Belongs to the UPF0754 family
H2783_RS16910	COG2259	Doxx family
H2783_RS16915	COG0586	Pfam SNARE associated Golgi protein
H2783_RS16930	COG1192	Involved in chromosome partitioning
H2783_RS16940	COG0271	Belongs to the BolA IbaG family
H2783_RS16960	COG2267	carboxylic ester hydrolase activity
H2783_RS16980	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H2783_RS16980	COG3321	synthase
H2783_RS16980	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H2783_RS16980	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H2783_RS16985	COG1960	acyl-CoA dehydrogenase activity
H2783_RS16995	COG2197	response regulator
H2783_RS17005	COG3916	Acyl-homoserine-lactone synthase
H2783_RS17010	COG0477	Major facilitator Superfamily
H2783_RS17015	COG1024	Enoyl-CoA hydratase
H2783_RS17020	COG1024	Enoyl-CoA hydratase
H2783_RS17025	COG1960	acyl-CoA dehydrogenase activity
H2783_RS17030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2783_RS17050	COG1113	amino acid transport
H2783_RS17055	COG1113	amino acid transport
H2783_RS17060	COG0251	oxidation-reduction process
H2783_RS17100	COG0564	pseudouridine synthase activity
H2783_RS17160	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H2783_RS17175	COG1802	Transcriptional regulator
H2783_RS17185	COG1448	Aminotransferase
H2783_RS17190	COG0277	FAD linked oxidase domain protein
H2783_RS17200	COG2186	Transcriptional regulator
H2783_RS17210	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2783_RS17215	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H2783_RS17230	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H2783_RS17235	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H2783_RS17240	COG1216	Glycosyl transferase, family 2
H2783_RS17270	COG2089	acid synthase
H2783_RS17285	COG1083	cytidylyl-transferase
H2783_RS17290	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
H2783_RS17295	COG1086	Polysaccharide biosynthesis protein
H2783_RS17300	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H2783_RS17305	COG1596	polysaccharide export
H2783_RS17330	COG0728	peptidoglycan biosynthetic process
H2783_RS17335	COG3023	N-Acetylmuramoyl-L-alanine amidase
H2783_RS17390	COG0546	phosphoglycolate phosphatase activity
H2783_RS17395	COG1028	Short-chain dehydrogenase reductase Sdr
H2783_RS17415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2783_RS17420	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2783_RS17425	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2783_RS17430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2783_RS17435	COG1116	anion transmembrane transporter activity
H2783_RS17440	COG1309	transcriptional regulator
H2783_RS17445	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H2783_RS17455	COG0196	riboflavin kinase activity
H2783_RS17460	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H2783_RS17470	COG1047	Peptidyl-prolyl cis-trans
H2783_RS17510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H2783_RS17515	COG0657	acetylesterase activity
H2783_RS17535	COG0583	DNA-binding transcription factor activity
H2783_RS17565	COG2951	lytic endotransglycosylase activity
H2783_RS17570	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H2783_RS17585	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H2783_RS17595	COG0671	phosphoesterase, PA-phosphatase related
H2783_RS17600	COG0861	Integral membrane protein TerC family
H2783_RS17610	COG0754	glutathionylspermidine amidase activity
H2783_RS17620	COG0402	S-adenosylhomocysteine deaminase activity
H2783_RS17635	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2783_RS17640	COG1230	cation diffusion facilitator family transporter
H2783_RS17655	COG0706	membrane insertase activity