locus-tag	class	description
D7A46_RS00085	COG0484	heat shock protein binding
D7A46_RS00560	COG0174	glutamine synthetase
D7A46_RS00610	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7A46_RS00615	COG2814	Major facilitator Superfamily
D7A46_RS00630	COG0583	DNA-binding transcription factor activity
D7A46_RS00645	COG1187	pseudouridine synthase activity
D7A46_RS00665	COG0802	atpase or kinase
D7A46_RS00670	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
D7A46_RS00680	COG1923	regulation of RNA biosynthetic process
D7A46_RS00685	COG0697	spore germination
D7A46_RS00700	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7A46_RS00710	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D7A46_RS00715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D7A46_RS00715	COG0519	Catalyzes the synthesis of GMP from XMP
D7A46_RS00720	COG4302	ethanolamine ammonia-lyase activity
D7A46_RS00725	COG4303	Ethanolamine ammonia lyase large subunit
D7A46_RS00730	COG0531	amino acid
D7A46_RS00750	COG1454	alcohol dehydrogenase
D7A46_RS00755	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D7A46_RS00765	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
D7A46_RS00785	COG0308	aminopeptidase N
D7A46_RS00815	COG1605	Chorismate mutase
D7A46_RS00835	COG1309	transcriptional regulator
D7A46_RS00845	COG0668	transmembrane transport
D7A46_RS00880	COG4773	Receptor
D7A46_RS00900	COG0488	(ABC) transporter
D7A46_RS00905	COG0589	response to stress
D7A46_RS00920	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
D7A46_RS00930	COG3135	benzoate transporter
D7A46_RS00935	COG1522	sequence-specific DNA binding
D7A46_RS00945	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
D7A46_RS00950	COG0583	DNA-binding transcription factor activity
D7A46_RS00960	COG0183	Belongs to the thiolase family
D7A46_RS00970	COG2030	dehydratase
D7A46_RS00975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D7A46_RS00990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
D7A46_RS01000	COG0824	Thioesterase
D7A46_RS01005	COG1454	alcohol dehydrogenase
D7A46_RS01015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
D7A46_RS01035	COG0069	glutamate synthase activity
D7A46_RS01200	COG5410	chromosome segregation
D7A46_RS01325	COG0739	heme binding
D7A46_RS01390	COG2814	Major facilitator Superfamily
D7A46_RS01405	COG0511	ligase activity, forming carbon-carbon bonds
D7A46_RS01425	COG1116	anion transmembrane transporter activity
D7A46_RS01425	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7A46_RS01430	COG0745	RESPONSE REGULATOR receiver
D7A46_RS01440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_RS01440	COG2146	nitrite reductase [NAD(P)H] activity
D7A46_RS01445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_RS01450	COG0243	molybdopterin cofactor binding
D7A46_RS01460	COG0243	molybdopterin cofactor binding
D7A46_RS01465	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
D7A46_RS01480	COG0521	Mo-molybdopterin cofactor biosynthetic process
D7A46_RS01480	COG0315	cyclic pyranopterin monophosphate synthase activity
D7A46_RS01485	COG0303	'Molybdopterin
D7A46_RS01495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7A46_RS01500	COG0697	spore germination
D7A46_RS01520	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
D7A46_RS01525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D7A46_RS01585	COG2204	response regulator
D7A46_RS01590	COG3852	Histidine kinase
D7A46_RS01615	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
D7A46_RS01620	COG0575	Belongs to the CDS family
D7A46_RS01655	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7A46_RS01670	COG2137	regulation of response to DNA damage stimulus
D7A46_RS01680	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
D7A46_RS01685	COG1011	Hydrolase
D7A46_RS01710	COG1522	sequence-specific DNA binding
D7A46_RS01720	COG1113	amino acid transport
D7A46_RS01735	COG0659	secondary active sulfate transmembrane transporter activity
D7A46_RS01740	COG2135	peptidase activity
D7A46_RS01755	COG5001	Diguanylate cyclase
D7A46_RS01755	COG3300	MHYT domain
D7A46_RS01775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D7A46_RS01775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
D7A46_RS01775	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
D7A46_RS01780	COG1105	Belongs to the carbohydrate kinase PfkB family
D7A46_RS01785	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
D7A46_RS01785	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
D7A46_RS01815	COG0024	Methionine aminopeptidase
D7A46_RS01820	COG0583	DNA-binding transcription factor activity
D7A46_RS01830	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
D7A46_RS01835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7A46_RS01840	COG0516	GMP reductase activity
D7A46_RS01840	COG0517	IMP dehydrogenase activity
D7A46_RS01865	COG0552	protein localization to endoplasmic reticulum
D7A46_RS01875	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
D7A46_RS01890	COG4890	Cyd operon protein YbgT
D7A46_RS01895	COG1294	oxidase, subunit
D7A46_RS01910	COG1585	Membrane protein implicated in regulation of membrane protease activity
D7A46_RS01920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
D7A46_RS01925	COG4774	siderophore transport
D7A46_RS01940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
D7A46_RS01945	COG0569	domain protein
D7A46_RS01950	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D7A46_RS01980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
D7A46_RS01985	COG0542	response to heat
D7A46_RS02010	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_RS02010	COG1902	pentaerythritol trinitrate reductase activity
D7A46_RS02055	COG2323	membrane
D7A46_RS02060	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
D7A46_RS02070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D7A46_RS02075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7A46_RS02080	COG0183	Belongs to the thiolase family
D7A46_RS02085	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
D7A46_RS02090	COG0596	Alpha beta hydrolase
D7A46_RS02095	COG2271	Major facilitator Superfamily
D7A46_RS02100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7A46_RS02105	COG3485	protocatechuate 3,4-dioxygenase
D7A46_RS02110	COG3485	protocatechuate 3,4-dioxygenase
D7A46_RS02115	COG0710	3-dehydroquinate dehydratase activity
D7A46_RS02120	COG3420	alginic acid biosynthetic process
D7A46_RS02125	COG3659	wide pore channel activity
D7A46_RS02130	COG4993	Dehydrogenase
D7A46_RS02140	COG2391	methyltransferase activity
D7A46_RS02155	COG1414	Transcriptional regulator
D7A46_RS02160	COG0583	DNA-binding transcription factor activity
D7A46_RS02165	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS02190	COG2814	Major facilitator Superfamily
D7A46_RS02200	COG0154	amidase activity
D7A46_RS02220	COG4638	Rieske (2fe-2S)
D7A46_RS02230	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS02240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_RS02250	COG3733	amine oxidase
D7A46_RS02260	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS02270	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7A46_RS02275	COG0183	Belongs to the thiolase family
D7A46_RS02280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7A46_RS02285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D7A46_RS02295	COG4829	muconolactone delta-isomerase
D7A46_RS02300	COG4948	Mandelate Racemase Muconate Lactonizing
D7A46_RS02305	COG0583	DNA-binding transcription factor activity
D7A46_RS02315	COG2186	Transcriptional regulator
D7A46_RS02335	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS02355	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS02360	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS02365	COG3829	transcription factor binding
D7A46_RS02375	COG3162	membrane
D7A46_RS02390	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS02405	COG0753	catalase activity
D7A46_RS02430	COG1846	Transcriptional regulator
D7A46_RS02435	COG1902	pentaerythritol trinitrate reductase activity
D7A46_RS02435	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_RS02445	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
D7A46_RS02475	COG1309	transcriptional regulator
D7A46_RS02485	COG1335	isochorismatase
D7A46_RS02490	COG0583	DNA-binding transcription factor activity
D7A46_RS02500	COG0475	glutathione-regulated potassium exporter activity
D7A46_RS02500	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7A46_RS02510	COG1473	amidohydrolase
D7A46_RS02525	COG2831	hemolysin activation secretion protein
D7A46_RS02530	COG3210	domain, Protein
D7A46_RS02560	COG2188	Transcriptional regulator
D7A46_RS02575	COG0583	DNA-binding transcription factor activity
D7A46_RS02605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D7A46_RS02625	COG1566	PFAM secretion protein HlyD family protein
D7A46_RS02640	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS02645	COG0129	dihydroxy-acid dehydratase activity
D7A46_RS02655	COG0583	DNA-binding transcription factor activity
D7A46_RS02660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
D7A46_RS02670	COG2084	Dehydrogenase
D7A46_RS02675	COG2207	Transcriptional regulator
D7A46_RS02690	COG1064	alcohol dehydrogenase
D7A46_RS02700	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D7A46_RS02705	COG1120	ATPase activity
D7A46_RS02725	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D7A46_RS02845	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
D7A46_RS02900	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS02915	COG2207	Transcriptional regulator
D7A46_RS02925	COG2205	protein histidine kinase activity
D7A46_RS02930	COG0745	RESPONSE REGULATOR receiver
D7A46_RS02935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_RS02940	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7A46_RS02945	COG1538	Outer membrane efflux protein
D7A46_RS02955	COG2072	flavoprotein involved in K transport
D7A46_RS02975	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7A46_RS02995	COG3539	Fimbrial protein
D7A46_RS03025	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
D7A46_RS03035	COG0753	catalase activity
D7A46_RS03050	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7A46_RS03115	COG1535	isochorismatase
D7A46_RS03115	COG3433	isochorismatase activity
D7A46_RS03120	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS03125	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
D7A46_RS03130	COG4149	molybdate abc transporter
D7A46_RS03135	COG0725	ABC transporter, periplasmic molybdate-binding protein
D7A46_RS03145	COG4638	Rieske (2fe-2S)
D7A46_RS03150	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D7A46_RS03155	COG0543	2 iron, 2 sulfur cluster binding
D7A46_RS03155	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7A46_RS03180	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS03195	COG2207	Transcriptional regulator
D7A46_RS03205	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS03210	COG2610	gluconate transmembrane transporter activity
D7A46_RS03220	COG0583	DNA-binding transcription factor activity
D7A46_RS03230	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7A46_RS03235	COG2031	fatty acid transporter
D7A46_RS03240	COG0183	Belongs to the thiolase family
D7A46_RS03245	COG0583	DNA-binding transcription factor activity
D7A46_RS03250	COG0583	DNA-binding transcription factor activity
D7A46_RS03265	COG1027	Aspartate ammonia-lyase
D7A46_RS03275	COG0477	Major facilitator Superfamily
D7A46_RS03295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7A46_RS03300	COG4521	taurine ABC transporter
D7A46_RS03315	COG2188	Transcriptional regulator
D7A46_RS03325	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
D7A46_RS03330	COG1733	regulation of RNA biosynthetic process
D7A46_RS03335	COG3708	Transcriptional regulator
D7A46_RS03335	COG2207	Transcriptional regulator
D7A46_RS03350	COG0730	response to heat
D7A46_RS03360	COG3453	Protein conserved in bacteria
D7A46_RS03360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7A46_RS03370	COG3781	membrane
D7A46_RS03375	COG1063	alcohol dehydrogenase
D7A46_RS03385	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7A46_RS03390	COG0508	dehydrogenase complex catalyzes the overall conversion of
D7A46_RS03395	COG0022	dehydrogenase e1 component
D7A46_RS03400	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
D7A46_RS03405	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D7A46_RS03420	COG3706	GGDEF domain
D7A46_RS03435	COG0133	tryptophan synthase activity
D7A46_RS03445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D7A46_RS03480	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
D7A46_RS03505	COG2226	methyltransferase
D7A46_RS03560	COG0842	Transport permease protein
D7A46_RS03565	COG0842	Transport permease protein
D7A46_RS03570	COG1131	(ABC) transporter
D7A46_RS03585	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
D7A46_RS03590	COG4773	Receptor
D7A46_RS03610	COG0730	response to heat
D7A46_RS03615	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
D7A46_RS03635	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
D7A46_RS03695	COG4264	IucA IucC family
D7A46_RS03700	COG4264	IucA IucC family
D7A46_RS03720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
D7A46_RS03735	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS03740	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS03745	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
D7A46_RS03750	COG2207	Transcriptional regulator
D7A46_RS03755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7A46_RS03760	COG0776	regulation of translation
D7A46_RS03785	COG0822	iron-sulfur transferase activity
D7A46_RS03790	COG0316	Belongs to the HesB IscA family
D7A46_RS03820	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
D7A46_RS03840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
D7A46_RS03845	COG0702	epimerase
D7A46_RS03880	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
D7A46_RS03890	COG0339	signal peptide processing
D7A46_RS03940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
D7A46_RS03945	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
D7A46_RS03975	COG0776	regulation of translation
D7A46_RS04040	COG0084	hydrolase, TatD family'
D7A46_RS04060	COG1663	tetraacyldisaccharide 4'-kinase activity
D7A46_RS04065	COG1132	(ABC) transporter
D7A46_RS04075	COG0811	peptide transport
D7A46_RS04080	COG1475	DNA binding
D7A46_RS04085	COG1192	Involved in chromosome partitioning
D7A46_RS04095	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
D7A46_RS04110	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
D7A46_RS04115	COG0191	fructose-bisphosphate aldolase activity
D7A46_RS04135	COG0424	maF-like protein
D7A46_RS04140	COG2850	peptidyl-arginine hydroxylation
D7A46_RS04150	COG0640	Transcriptional regulator
D7A46_RS04165	COG3619	membrane
D7A46_RS04170	COG3122	Protein conserved in bacteria
D7A46_RS04175	COG1132	(ABC) transporter
D7A46_RS04195	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
D7A46_RS04200	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D7A46_RS04210	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D7A46_RS04210	COG0506	proline dehydrogenase activity
D7A46_RS04210	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
D7A46_RS04215	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
D7A46_RS04230	COG3698	Phosphodiester glycosidase
D7A46_RS04240	COG2353	YceI-like domain
D7A46_RS04250	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
D7A46_RS04295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
D7A46_RS04295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
D7A46_RS04320	COG3539	Fimbrial protein
D7A46_RS04325	COG3121	Chaperone
D7A46_RS04355	COG0697	spore germination
D7A46_RS04365	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D7A46_RS04375	COG0583	DNA-binding transcription factor activity
D7A46_RS04395	COG1309	transcriptional regulator
D7A46_RS04410	COG1522	sequence-specific DNA binding
D7A46_RS04420	COG1126	abc transporter atp-binding protein
D7A46_RS04425	COG0765	amino acid transport
D7A46_RS04430	COG0765	amino acid transport
D7A46_RS04460	COG1464	Belongs to the NlpA lipoprotein family
D7A46_RS04470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D7A46_RS04475	COG2011	ABC-type metal ion transport system permease component
D7A46_RS04480	COG0012	GTP binding
D7A46_RS04505	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D7A46_RS04545	COG0386	Belongs to the glutathione peroxidase family
D7A46_RS04555	COG0436	Aminotransferase
D7A46_RS04595	COG3634	alkyl hydroperoxide reductase activity
D7A46_RS04610	COG0583	DNA-binding transcription factor activity
D7A46_RS04615	COG0798	PFAM Bile acid sodium symporter
D7A46_RS04620	COG0640	Transcriptional regulator
D7A46_RS04635	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
D7A46_RS04645	COG0583	DNA-binding transcription factor activity
D7A46_RS04655	COG1953	Uracil, thiamine, allantoin
D7A46_RS04665	COG2175	clavaminate synthase activity
D7A46_RS04670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7A46_RS04675	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
D7A46_RS04680	COG4521	taurine ABC transporter
D7A46_RS04690	COG0477	Major facilitator Superfamily
D7A46_RS04715	COG1271	oxidase subunit
D7A46_RS04720	COG1294	oxidase, subunit
D7A46_RS04730	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7A46_RS04750	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
D7A46_RS04770	COG3052	prosthetic group binding
D7A46_RS04775	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
D7A46_RS04785	COG2814	Major facilitator Superfamily
D7A46_RS04805	COG1346	cytolysis
D7A46_RS04815	COG0583	DNA-binding transcription factor activity
D7A46_RS04820	COG0625	glutathione transferase activity
D7A46_RS04825	COG0625	glutathione transferase activity
D7A46_RS04830	COG0583	DNA-binding transcription factor activity
D7A46_RS04845	COG1045	serine acetyltransferase
D7A46_RS04850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
D7A46_RS04855	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
D7A46_RS04865	COG1280	lysine exporter protein (LysE YggA)
D7A46_RS04880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7A46_RS04885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7A46_RS04890	COG1126	abc transporter atp-binding protein
D7A46_RS04895	COG0765	amino acid transport
D7A46_RS04900	COG0765	amino acid transport
D7A46_RS04920	COG0784	Response regulator, receiver
D7A46_RS04920	COG2205	protein histidine kinase activity
D7A46_RS04940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
D7A46_RS04960	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS05005	COG0583	DNA-binding transcription factor activity
D7A46_RS05025	COG0318	PFAM AMP-dependent synthetase and ligase
D7A46_RS05030	COG1309	transcriptional regulator
D7A46_RS05035	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS05040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D7A46_RS05045	COG1024	Enoyl-CoA hydratase
D7A46_RS05050	COG4770	biotin carboxylase activity
D7A46_RS05060	COG0583	DNA-binding transcription factor activity
D7A46_RS05075	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS05085	COG2814	Major facilitator Superfamily
D7A46_RS05095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
D7A46_RS05100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
D7A46_RS05105	COG2814	Major facilitator Superfamily
D7A46_RS05110	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS05115	COG1024	Enoyl-CoA hydratase
D7A46_RS05120	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS05125	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7A46_RS05130	COG0183	Belongs to the thiolase family
D7A46_RS05140	COG2814	Major facilitator Superfamily
D7A46_RS05150	COG1024	Enoyl-CoA hydratase
D7A46_RS05165	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS05170	COG2814	Major facilitator Superfamily
D7A46_RS05175	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
D7A46_RS05180	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
D7A46_RS05195	COG3842	ATPase activity
D7A46_RS05200	COG1840	ABC-type Fe3 transport system, periplasmic component
D7A46_RS05210	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_RS05215	COG1414	Transcriptional regulator
D7A46_RS05225	COG0583	DNA-binding transcription factor activity
D7A46_RS05230	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
D7A46_RS05235	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS05245	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
D7A46_RS05255	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS05260	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7A46_RS05265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_RS05270	COG2267	carboxylic ester hydrolase activity
D7A46_RS05290	COG3038	cytochrome b561
D7A46_RS05295	COG0753	catalase activity
D7A46_RS05335	COG2050	protein possibly involved in aromatic compounds catabolism
D7A46_RS05345	COG3327	negative regulation of DNA-templated transcription, initiation
D7A46_RS05350	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
D7A46_RS05355	COG0183	Belongs to the thiolase family
D7A46_RS05360	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7A46_RS05365	COG1024	Enoyl-CoA hydratase
D7A46_RS05370	COG1024	Enoyl-CoA hydratase
D7A46_RS05375	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7A46_RS05380	COG2151	metal-sulfur cluster biosynthetic enzyme
D7A46_RS05385	COG3396	Phenylacetate-CoA oxygenase
D7A46_RS05390	COG3460	Phenylacetate-CoA oxygenase
D7A46_RS05395	COG3396	Phenylacetate-CoA oxygenase
D7A46_RS05400	COG2030	dehydratase
D7A46_RS05400	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS05405	COG1760	l-serine dehydratase
D7A46_RS05410	COG0531	amino acid
D7A46_RS05415	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS05430	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_RS05440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7A46_RS05460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7A46_RS05475	COG0789	Transcriptional regulator
D7A46_RS05490	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
D7A46_RS05505	COG2807	transmembrane transport
D7A46_RS05510	COG0590	tRNA wobble adenosine to inosine editing
D7A46_RS05630	COG1116	anion transmembrane transporter activity
D7A46_RS05635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
D7A46_RS05645	COG0864	Transcriptional regulator
D7A46_RS05665	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7A46_RS05670	COG0439	Biotin carboxylase
D7A46_RS05685	COG1063	alcohol dehydrogenase
D7A46_RS05695	COG1309	transcriptional regulator
D7A46_RS05720	COG0038	chloride channel
D7A46_RS05725	COG4770	biotin carboxylase activity
D7A46_RS05745	COG1914	H( )-stimulated, divalent metal cation uptake system
D7A46_RS05750	COG0583	DNA-binding transcription factor activity
D7A46_RS05805	COG1250	3-hydroxyacyl-CoA dehydrogenase
D7A46_RS05825	COG2814	Major facilitator Superfamily
D7A46_RS05840	COG1560	Kdo2-lipid A biosynthetic process
D7A46_RS05850	COG5006	permease, DMT superfamily
D7A46_RS05855	COG1522	sequence-specific DNA binding
D7A46_RS05870	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
D7A46_RS05880	COG4122	O-methyltransferase activity
D7A46_RS05910	COG1538	Outer membrane efflux protein
D7A46_RS05915	COG1137	ATPase activity
D7A46_RS05920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
D7A46_RS05930	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
D7A46_RS05935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
D7A46_RS05935	COG0517	IMP dehydrogenase activity
D7A46_RS05975	COG2814	Major facilitator Superfamily
D7A46_RS06015	COG1278	Cold shock
D7A46_RS06020	COG1280	lysine exporter protein (LysE YggA)
D7A46_RS06055	COG1570	exodeoxyribonuclease VII activity
D7A46_RS06110	COG0583	DNA-binding transcription factor activity
D7A46_RS06115	COG4638	Rieske (2fe-2S)
D7A46_RS06120	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
D7A46_RS06125	COG0543	2 iron, 2 sulfur cluster binding
D7A46_RS06125	COG0633	Ferredoxin
D7A46_RS06130	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS06135	COG3135	benzoate transporter
D7A46_RS06140	COG2814	Major facilitator Superfamily
D7A46_RS06155	COG1643	Atp-dependent helicase
D7A46_RS06160	COG0450	alkyl hydroperoxide reductase
D7A46_RS06170	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
D7A46_RS06180	COG3634	alkyl hydroperoxide reductase activity
D7A46_RS06200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
D7A46_RS06205	COG0625	glutathione transferase activity
D7A46_RS06215	COG2885	chlorophyll binding
D7A46_RS06250	COG0542	response to heat
D7A46_RS06265	COG1765	OsmC-like protein
D7A46_RS06370	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
D7A46_RS06380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
D7A46_RS06390	COG0527	aspartate kinase activity
D7A46_RS06400	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
D7A46_RS06410	COG3038	cytochrome b561
D7A46_RS06415	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
D7A46_RS06420	COG2252	PERMEase
D7A46_RS06430	COG2072	flavoprotein involved in K transport
D7A46_RS06445	COG1741	Belongs to the pirin family
D7A46_RS06450	COG1309	transcriptional regulator
D7A46_RS06475	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_RS06475	COG1902	pentaerythritol trinitrate reductase activity
D7A46_RS06485	COG5001	Diguanylate cyclase
D7A46_RS06485	COG4251	negative regulation of phosphorylation
D7A46_RS06485	COG3706	GGDEF domain
D7A46_RS06485	COG2203	Gaf domain
D7A46_RS06495	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7A46_RS06515	COG4172	Belongs to the ABC transporter superfamily
D7A46_RS06520	COG4239	(ABC) transporter, permease
D7A46_RS06525	COG4174	ABC transporter (Permease)
D7A46_RS06535	COG1388	LysM domain
D7A46_RS06535	COG1388	LysM domain
D7A46_RS06535	COG0741	lytic transglycosylase activity
D7A46_RS06535	COG0741	lytic transglycosylase activity
D7A46_RS06540	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7A46_RS06580	COG0583	DNA-binding transcription factor activity
D7A46_RS06585	COG1279	arginine transmembrane transporter activity
D7A46_RS06605	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_RS06610	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_RS06615	COG0006	proline dipeptidase activity
D7A46_RS06650	COG2194	sulfuric ester hydrolase activity
D7A46_RS06695	COG0739	heme binding
D7A46_RS07025	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
D7A46_RS07050	COG3384	dioxygenase
D7A46_RS07060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D7A46_RS07065	COG2878	Part of a membrane complex involved in electron transport
D7A46_RS07070	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
D7A46_RS07095	COG0768	penicillin binding
D7A46_RS07100	COG0742	ribosomal rna small subunit methyltransferase
D7A46_RS07115	COG0830	nickel cation binding
D7A46_RS07125	COG0804	urea catabolic process
D7A46_RS07165	COG1253	flavin adenine dinucleotide binding
D7A46_RS07175	COG2851	Citrate transporter
D7A46_RS07230	COG1773	rubredoxin
D7A46_RS07235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_RS07245	COG0583	DNA-binding transcription factor activity
D7A46_RS07270	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
D7A46_RS07275	COG4181	ATPase activity
D7A46_RS07320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
D7A46_RS07340	COG0306	phosphate transporter
D7A46_RS07350	COG3958	Transketolase
D7A46_RS07355	COG3959	Transketolase, thiamine diphosphate binding domain
D7A46_RS07360	COG2271	Major facilitator Superfamily
D7A46_RS07365	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS07370	COG0583	DNA-binding transcription factor activity
D7A46_RS07390	COG2223	nitrite transmembrane transporter activity
D7A46_RS07395	COG2207	Transcriptional regulator
D7A46_RS07400	COG2066	Belongs to the glutaminase family
D7A46_RS07405	COG0242	peptide deformylase activity
D7A46_RS07410	COG0477	Major facilitator Superfamily
D7A46_RS07420	COG0028	Belongs to the TPP enzyme family
D7A46_RS07435	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS07440	COG2267	carboxylic ester hydrolase activity
D7A46_RS07450	COG2271	Major facilitator Superfamily
D7A46_RS07455	COG0446	pyridine nucleotide-disulphide oxidoreductase
D7A46_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS07485	COG1414	Transcriptional regulator
D7A46_RS07500	COG1024	Enoyl-CoA hydratase
D7A46_RS07510	COG1215	transferase activity, transferring glycosyl groups
D7A46_RS07515	COG1649	PFAM Uncharacterised BCR, COG1649
D7A46_RS07515	COG0726	polysaccharide deacetylase
D7A46_RS07525	COG4681	YaeQ
D7A46_RS07535	COG0523	cobalamin synthesis protein
D7A46_RS07545	COG1607	acyl-coa hydrolase
D7A46_RS07555	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_RS07560	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_RS07565	COG1309	transcriptional regulator
D7A46_RS07590	COG2040	homocysteine
D7A46_RS07595	COG0531	amino acid
D7A46_RS07650	COG1595	DNA-templated transcription, initiation
D7A46_RS07660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7A46_RS07665	COG0477	Major facilitator Superfamily
D7A46_RS07685	COG0084	hydrolase, TatD family'
D7A46_RS07775	COG0582	viral genome integration into host DNA
D7A46_RS07870	COG0592	DNA-directed DNA polymerase activity
D7A46_RS07910	COG2026	Addiction module toxin, RelE StbE family
D7A46_RS08105	COG1484	DNA-dependent DNA replication
D7A46_RS08195	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
D7A46_RS08260	COG0405	Gamma-glutamyltransferase
D7A46_RS08265	COG2814	Major facilitator Superfamily
D7A46_RS08275	COG2050	protein possibly involved in aromatic compounds catabolism
D7A46_RS08290	COG1090	epimerase
D7A46_RS08310	COG0420	3'-5' exonuclease activity
D7A46_RS08335	COG0735	belongs to the Fur family
D7A46_RS08340	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D7A46_RS08365	COG0121	glutamine amidotransferase
D7A46_RS08380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7A46_RS08390	COG0210	DNA helicase
D7A46_RS08395	COG2885	chlorophyll binding
D7A46_RS08400	COG0204	Acyl-transferase
D7A46_RS08415	COG2894	cell division
D7A46_RS08435	COG1280	lysine exporter protein (LysE YggA)
D7A46_RS08440	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
D7A46_RS08440	COG1674	ftsk spoiiie
D7A46_RS08445	COG0492	ferredoxin-NADP+ reductase activity
D7A46_RS08450	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
D7A46_RS08460	COG0456	acetyltransferase
D7A46_RS08505	COG1981	membrane
D7A46_RS08520	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D7A46_RS08520	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
D7A46_RS08540	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS08550	COG0657	acetylesterase activity
D7A46_RS08560	COG0473	3-isopropylmalate dehydrogenase activity
D7A46_RS08565	COG0583	DNA-binding transcription factor activity
D7A46_RS08585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D7A46_RS08610	COG0564	pseudouridine synthase activity
D7A46_RS08620	COG0358	DNA primase activity
D7A46_RS08635	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
D7A46_RS08665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
D7A46_RS08695	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
D7A46_RS08705	COG0352	thiamine-phosphate diphosphorylase activity
D7A46_RS08705	COG0351	phosphomethylpyrimidine kinase
D7A46_RS08705	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D7A46_RS08710	COG1652	LysM domain
D7A46_RS08735	COG1399	metal-binding, possibly nucleic acid-binding protein
D7A46_RS08740	COG3101	peptidyl-lysine hydroxylation
D7A46_RS08745	COG0009	L-threonylcarbamoyladenylate synthase
D7A46_RS08750	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
D7A46_RS08755	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
D7A46_RS08770	COG4106	trans-aconitate 2-methyltransferase activity
D7A46_RS08785	COG0596	Alpha beta hydrolase
D7A46_RS08785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7A46_RS08785	COG2226	methyltransferase
D7A46_RS08790	COG1877	trehalose-phosphatase activity
D7A46_RS08795	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
D7A46_RS08800	COG2223	nitrite transmembrane transporter activity
D7A46_RS08820	COG1196	nuclear chromosome segregation
D7A46_RS08830	COG0730	response to heat
D7A46_RS08845	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
D7A46_RS08855	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D7A46_RS08915	COG0489	protein tyrosine kinase activity
D7A46_RS08925	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7A46_RS08925	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7A46_RS08955	COG2515	1-aminocyclopropane-1-carboxylate deaminase
D7A46_RS08960	COG2081	HI0933 family
D7A46_RS08970	COG0668	transmembrane transport
D7A46_RS08990	COG0583	DNA-binding transcription factor activity
D7A46_RS09010	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
D7A46_RS09015	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D7A46_RS09045	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D7A46_RS09085	COG0745	RESPONSE REGULATOR receiver
D7A46_RS09105	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
D7A46_RS09115	COG2205	protein histidine kinase activity
D7A46_RS09185	COG4993	Dehydrogenase
D7A46_RS09205	COG0384	phenazine biosynthesis protein PhzF
D7A46_RS09235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_RS09250	COG0583	DNA-binding transcription factor activity
D7A46_RS09280	COG0583	DNA-binding transcription factor activity
D7A46_RS09300	COG0583	DNA-binding transcription factor activity
D7A46_RS09305	COG1053	succinate dehydrogenase
D7A46_RS09315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
D7A46_RS09320	COG2814	Major facilitator Superfamily
D7A46_RS09325	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS09330	COG0583	DNA-binding transcription factor activity
D7A46_RS09335	COG1063	alcohol dehydrogenase
D7A46_RS09365	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
D7A46_RS09370	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
D7A46_RS09375	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D7A46_RS09390	COG3667	copper resistance
D7A46_RS09395	COG2132	Multicopper oxidase
D7A46_RS09405	COG0561	phosphatase activity
D7A46_RS09410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
D7A46_RS09435	COG1214	PFAM Peptidase M22, glycoprotease
D7A46_RS09490	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
D7A46_RS09500	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
D7A46_RS09505	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
D7A46_RS09510	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
D7A46_RS09570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
D7A46_RS09580	COG1846	Transcriptional regulator
D7A46_RS09585	COG1764	response to oxidative stress
D7A46_RS09635	COG0037	tRNA processing
D7A46_RS09645	COG0248	Ppx GppA phosphatase
D7A46_RS09675	COG0072	phenylalanine-tRNA ligase activity
D7A46_RS09715	COG1238	metal cluster binding
D7A46_RS09720	COG0625	glutathione transferase activity
D7A46_RS09740	COG0318	PFAM AMP-dependent synthetase and ligase
D7A46_RS09745	COG3028	Belongs to the UPF0307 family
D7A46_RS09750	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
D7A46_RS09770	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D7A46_RS09775	COG0617	tRNA 3'-terminal CCA addition
D7A46_RS09780	COG1555	photosystem II stabilization
D7A46_RS09785	COG3956	TIGRFAM MazG family protein
D7A46_RS09795	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D7A46_RS09815	COG2205	protein histidine kinase activity
D7A46_RS09815	COG5002	protein histidine kinase activity
D7A46_RS09815	COG0784	Response regulator, receiver
D7A46_RS09820	COG1024	Enoyl-CoA hydratase
D7A46_RS09825	COG2084	Dehydrogenase
D7A46_RS09830	COG3622	Belongs to the hyi family
D7A46_RS09860	COG0697	spore germination
D7A46_RS09870	COG2814	Major facilitator Superfamily
D7A46_RS09875	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
D7A46_RS09885	COG0583	DNA-binding transcription factor activity
D7A46_RS09895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
D7A46_RS09910	COG0084	hydrolase, TatD family'
D7A46_RS09925	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
D7A46_RS09960	COG0440	acetolactate synthase activity
D7A46_RS09965	COG0028	Belongs to the TPP enzyme family
D7A46_RS09990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_RS09995	COG1136	(ABC) transporter
D7A46_RS09995	COG0577	efflux transmembrane transporter activity
D7A46_RS10000	COG1538	Outer membrane efflux protein
D7A46_RS10015	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
D7A46_RS10020	COG1162	GTPase activity
D7A46_RS10030	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
D7A46_RS10050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
D7A46_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS10095	COG2986	histidine ammonia-lyase
D7A46_RS10110	COG0318	PFAM AMP-dependent synthetase and ligase
D7A46_RS10120	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D7A46_RS10165	COG1426	Protein conserved in bacteria
D7A46_RS10200	COG0793	Belongs to the peptidase S41A family
D7A46_RS10215	COG2267	carboxylic ester hydrolase activity
D7A46_RS10225	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS10230	COG3265	gluconokinase activity
D7A46_RS10240	COG0800	Aldolase
D7A46_RS10255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
D7A46_RS10260	COG0857	belongs to the CobB CobQ family
D7A46_RS10260	COG0280	phosphate acetyltransferase
D7A46_RS10265	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
D7A46_RS10265	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
D7A46_RS10285	COG0740	serine-type endopeptidase activity
D7A46_RS10295	COG4774	siderophore transport
D7A46_RS10305	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
D7A46_RS10315	COG2813	Specifically methylates the guanine in position
D7A46_RS10315	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
D7A46_RS10415	COG0788	formyltetrahydrofolate deformylase activity
D7A46_RS10440	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7A46_RS10440	COG4651	solute:proton antiporter activity
D7A46_RS10460	COG0724	RNA recognition motif
D7A46_RS10465	COG0210	DNA helicase
D7A46_RS10490	COG1733	regulation of RNA biosynthetic process
D7A46_RS10500	COG2900	Belongs to the SlyX family
D7A46_RS10505	COG0488	(ABC) transporter
D7A46_RS10510	COG1280	lysine exporter protein (LysE YggA)
D7A46_RS10515	COG1560	Kdo2-lipid A biosynthetic process
D7A46_RS10525	COG1301	dicarboxylic acid transport
D7A46_RS10580	COG0473	3-isopropylmalate dehydrogenase activity
D7A46_RS10645	COG0583	DNA-binding transcription factor activity
D7A46_RS10655	COG0625	glutathione transferase activity
D7A46_RS10660	COG2378	regulation of single-species biofilm formation
D7A46_RS10665	COG0546	phosphoglycolate phosphatase activity
D7A46_RS10680	COG1530	ribonuclease E activity
D7A46_RS10685	COG0318	PFAM AMP-dependent synthetase and ligase
D7A46_RS10700	COG0583	DNA-binding transcription factor activity
D7A46_RS10705	COG4221	oxidoreductase activity
D7A46_RS10710	COG0635	Involved in the biosynthesis of porphyrin-containing compound
D7A46_RS10720	COG0534	Mate efflux family protein
D7A46_RS10735	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
D7A46_RS10775	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
D7A46_RS10780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7A46_RS10795	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D7A46_RS10805	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
D7A46_RS10805	COG0644	oxidoreductase
D7A46_RS10810	COG0425	Belongs to the sulfur carrier protein TusA family
D7A46_RS10815	COG4535	Mg2 and Co2 transporter CorC
D7A46_RS10825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
D7A46_RS10845	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
D7A46_RS10850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
D7A46_RS10850	COG0475	glutathione-regulated potassium exporter activity
D7A46_RS10855	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
D7A46_RS10865	COG0484	heat shock protein binding
D7A46_RS10870	COG0789	Transcriptional regulator
D7A46_RS10875	COG0598	Magnesium transport protein CorA
D7A46_RS10890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
D7A46_RS10895	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
D7A46_RS10900	COG1074	ATP-dependent DNA helicase activity
D7A46_RS10905	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
D7A46_RS10925	COG2226	methyltransferase
D7A46_RS10940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_RS10945	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
D7A46_RS10960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
D7A46_RS10960	COG2111	Na H antiporter
D7A46_RS10965	COG1006	Multisubunit Na H antiporter MnhC subunit
D7A46_RS10970	COG0651	ATP synthesis coupled electron transport
D7A46_RS10975	COG1863	multisubunit Na H antiporter MnhE subunit
D7A46_RS10980	COG2212	antiporter activity
D7A46_RS10985	COG1320	monovalent cation:proton antiporter activity
D7A46_RS11000	COG0195	Participates in both transcription termination and antitermination
D7A46_RS11050	COG0237	dephospho-CoA kinase activity
D7A46_RS11060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D7A46_RS11075	COG0497	DNA recombination
D7A46_RS11085	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
D7A46_RS11115	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
D7A46_RS11115	COG2169	Transcriptional regulator
D7A46_RS11120	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
D7A46_RS11190	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
D7A46_RS11205	COG0326	Molecular chaperone. Has ATPase activity
D7A46_RS11220	COG2056	Na+-H+ antiporter family
D7A46_RS11225	COG0596	Alpha beta hydrolase
D7A46_RS11320	COG0546	phosphoglycolate phosphatase activity
D7A46_RS11325	COG1716	ATPase activity
D7A46_RS11370	COG0181	hydroxymethylbilane synthase activity
D7A46_RS11380	COG3275	phosphorelay sensor kinase activity
D7A46_RS11400	COG1538	Outer membrane efflux protein
D7A46_RS11405	COG0697	spore germination
D7A46_RS11430	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D7A46_RS11435	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
D7A46_RS11440	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
D7A46_RS11445	COG0772	Belongs to the SEDS family
D7A46_RS11470	COG4974	Belongs to the 'phage' integrase family
D7A46_RS11475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D7A46_RS11485	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
D7A46_RS11510	COG0793	Belongs to the peptidase S41A family
D7A46_RS11515	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
D7A46_RS11520	COG0795	lipopolysaccharide-transporting ATPase activity
D7A46_RS11560	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7A46_RS11560	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
D7A46_RS11570	COG0004	ammonium transporteR
D7A46_RS11575	COG0347	Belongs to the P(II) protein family
D7A46_RS11585	COG0606	chelatase, subunit chli
D7A46_RS11655	COG1061	Type III restriction enzyme res subunit
D7A46_RS11670	COG0659	secondary active sulfate transmembrane transporter activity
D7A46_RS11675	COG0589	response to stress
D7A46_RS11720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7A46_RS11770	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D7A46_RS11815	COG1061	Type III restriction enzyme res subunit
D7A46_RS11830	COG0659	secondary active sulfate transmembrane transporter activity
D7A46_RS11835	COG0589	response to stress
D7A46_RS11865	COG0606	chelatase, subunit chli
D7A46_RS11880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7A46_RS11895	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
D7A46_RS11910	COG0318	PFAM AMP-dependent synthetase and ligase
D7A46_RS11920	COG0477	Major facilitator Superfamily
D7A46_RS11925	COG2860	membrane
D7A46_RS11935	COG1253	flavin adenine dinucleotide binding
D7A46_RS11955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
D7A46_RS11990	COG0655	NAD(P)H dehydrogenase (quinone) activity
D7A46_RS12000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
D7A46_RS12035	COG1309	transcriptional regulator
D7A46_RS12070	COG0758	DNA mediated transformation
D7A46_RS12080	COG0697	spore germination
D7A46_RS12085	COG1309	transcriptional regulator
D7A46_RS12100	COG0386	Belongs to the glutathione peroxidase family
D7A46_RS12165	COG1121	(ABC) transporter
D7A46_RS12170	COG1108	ABC-type Mn2 Zn2 transport systems permease components
D7A46_RS12175	COG1280	lysine exporter protein (LysE YggA)
D7A46_RS12180	COG2837	iron assimilation
D7A46_RS12190	COG0281	malic enzyme
D7A46_RS12235	COG0519	Catalyzes the synthesis of GMP from XMP
D7A46_RS12235	COG0518	GMP synthase (glutamine-hydrolyzing) activity
D7A46_RS12240	COG4399	Belongs to the UPF0754 family
D7A46_RS12245	COG2259	Doxx family
D7A46_RS12250	COG0586	Pfam SNARE associated Golgi protein
D7A46_RS12265	COG1192	Involved in chromosome partitioning
D7A46_RS12275	COG0271	Belongs to the BolA IbaG family
D7A46_RS12295	COG2267	carboxylic ester hydrolase activity
D7A46_RS12315	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
D7A46_RS12315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
D7A46_RS12315	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
D7A46_RS12315	COG3321	synthase
D7A46_RS12320	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS12330	COG2197	response regulator
D7A46_RS12340	COG3916	Acyl-homoserine-lactone synthase
D7A46_RS12345	COG0477	Major facilitator Superfamily
D7A46_RS12350	COG1024	Enoyl-CoA hydratase
D7A46_RS12355	COG1024	Enoyl-CoA hydratase
D7A46_RS12360	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS12365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7A46_RS12385	COG1113	amino acid transport
D7A46_RS12390	COG1113	amino acid transport
D7A46_RS12395	COG0251	oxidation-reduction process
D7A46_RS12435	COG0564	pseudouridine synthase activity
D7A46_RS12500	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
D7A46_RS12515	COG1802	Transcriptional regulator
D7A46_RS12525	COG1448	Aminotransferase
D7A46_RS12530	COG0277	FAD linked oxidase domain protein
D7A46_RS12540	COG2186	Transcriptional regulator
D7A46_RS12550	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
D7A46_RS12555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
D7A46_RS12570	COG1210	Utp--glucose-1-phosphate uridylyltransferase
D7A46_RS12575	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
D7A46_RS12600	COG0438	transferase activity, transferring glycosyl groups
D7A46_RS12630	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
D7A46_RS12670	COG0728	peptidoglycan biosynthetic process
D7A46_RS12675	COG3023	N-Acetylmuramoyl-L-alanine amidase
D7A46_RS12730	COG0546	phosphoglycolate phosphatase activity
D7A46_RS12735	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS12755	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7A46_RS12760	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7A46_RS12765	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7A46_RS12770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7A46_RS12775	COG1116	anion transmembrane transporter activity
D7A46_RS12780	COG1309	transcriptional regulator
D7A46_RS12785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
D7A46_RS12800	COG1061	Type III restriction enzyme res subunit
D7A46_RS12825	COG0196	riboflavin kinase activity
D7A46_RS12830	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
D7A46_RS12840	COG1047	Peptidyl-prolyl cis-trans
D7A46_RS12880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
D7A46_RS12885	COG0657	acetylesterase activity
D7A46_RS12935	COG2951	lytic endotransglycosylase activity
D7A46_RS12940	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
D7A46_RS12960	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
D7A46_RS12970	COG0671	phosphoesterase, PA-phosphatase related
D7A46_RS12975	COG0861	Integral membrane protein TerC family
D7A46_RS12985	COG0754	glutathionylspermidine amidase activity
D7A46_RS12995	COG0402	S-adenosylhomocysteine deaminase activity
D7A46_RS13010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D7A46_RS13015	COG1230	cation diffusion facilitator family transporter
D7A46_RS13030	COG0706	membrane insertase activity
D7A46_RS13055	COG0592	DNA-directed DNA polymerase activity
D7A46_RS13065	COG0187	DNA topoisomerase II activity
D7A46_RS13075	COG0586	Pfam SNARE associated Golgi protein
D7A46_RS13080	COG0488	(ABC) transporter
D7A46_RS13105	COG0596	Alpha beta hydrolase
D7A46_RS13110	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
D7A46_RS13115	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
D7A46_RS13160	COG0733	neurotransmitter:sodium symporter activity
D7A46_RS13200	COG2233	PERMEase
D7A46_RS13215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_RS13250	COG2814	Major facilitator Superfamily
D7A46_RS13255	COG0656	L-ascorbic acid biosynthetic process
D7A46_RS13260	COG0583	DNA-binding transcription factor activity
D7A46_RS13275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7A46_RS13280	COG1064	alcohol dehydrogenase
D7A46_RS13285	COG2818	Glycosylase
D7A46_RS13300	COG1194	a g-specific adenine glycosylase
D7A46_RS13320	COG2983	Belongs to the UPF0260 family
D7A46_RS13325	COG2133	pyrroloquinoline quinone binding
D7A46_RS13330	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
D7A46_RS13335	COG2116	formate transmembrane transporter activity
D7A46_RS13355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
D7A46_RS13360	COG1335	isochorismatase
D7A46_RS13365	COG0385	Bile acid
D7A46_RS13370	COG0534	Mate efflux family protein
D7A46_RS13375	COG1683	Conserved Protein
D7A46_RS13395	COG0625	glutathione transferase activity
D7A46_RS13405	COG1113	amino acid transport
D7A46_RS13415	COG0523	cobalamin synthesis protein
D7A46_RS13425	COG2188	Transcriptional regulator
D7A46_RS13455	COG0010	Belongs to the arginase family
D7A46_RS13470	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
D7A46_RS13475	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
D7A46_RS13485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
D7A46_RS13490	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
D7A46_RS13595	COG0534	Mate efflux family protein
D7A46_RS13600	COG0436	Aminotransferase
D7A46_RS13605	COG2733	membrane
D7A46_RS13620	COG2918	glutathione biosynthetic process
D7A46_RS13635	COG1388	LysM domain
D7A46_RS13635	COG0791	NLP P60 protein
D7A46_RS13650	COG3150	esterase
D7A46_RS13660	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS13665	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
D7A46_RS13675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
D7A46_RS13685	COG2233	PERMEase
D7A46_RS13690	COG2351	hydroxyisourate hydrolase activity
D7A46_RS13725	COG3706	GGDEF domain
D7A46_RS13740	COG1393	Belongs to the ArsC family
D7A46_RS13745	COG0708	Exodeoxyribonuclease III
D7A46_RS13765	COG0189	ligase activity
D7A46_RS13785	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
D7A46_RS13795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
D7A46_RS13810	COG4942	peptidase
D7A46_RS13820	COG0508	dehydrogenase complex catalyzes the overall conversion of
D7A46_RS13830	COG2119	membrane
D7A46_RS13835	COG4774	siderophore transport
D7A46_RS13840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_RS13840	COG0426	domain, Protein
D7A46_RS13865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
D7A46_RS13885	COG1902	pentaerythritol trinitrate reductase activity
D7A46_RS13890	COG1519	Transferase
D7A46_RS13895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D7A46_RS13900	COG0668	transmembrane transport
D7A46_RS13910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7A46_RS13915	COG1335	isochorismatase
D7A46_RS13920	COG1522	sequence-specific DNA binding
D7A46_RS13925	COG3328	transposase activity
D7A46_RS13950	COG0784	Response regulator, receiver
D7A46_RS13950	COG2205	protein histidine kinase activity
D7A46_RS13950	COG2198	Histidine kinase
D7A46_RS13955	COG3162	membrane
D7A46_RS13960	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
D7A46_RS13970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_RS13990	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
D7A46_RS13995	COG1309	transcriptional regulator
D7A46_RS14015	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
D7A46_RS14015	COG0352	thiamine-phosphate diphosphorylase activity
D7A46_RS14015	COG0351	phosphomethylpyrimidine kinase
D7A46_RS14025	COG2814	Major facilitator Superfamily
D7A46_RS14040	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
D7A46_RS14050	COG1113	amino acid transport
D7A46_RS14060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D7A46_RS14065	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS14075	COG1335	isochorismatase
D7A46_RS14105	COG2814	Major facilitator Superfamily
D7A46_RS14110	COG0583	DNA-binding transcription factor activity
D7A46_RS14130	COG0667	Aldo Keto reductase
D7A46_RS14170	COG1733	regulation of RNA biosynthetic process
D7A46_RS14180	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7A46_RS14245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
D7A46_RS14260	COG2329	Antibiotic biosynthesis monooxygenase
D7A46_RS14290	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
D7A46_RS14345	COG0659	secondary active sulfate transmembrane transporter activity
D7A46_RS14350	COG4221	oxidoreductase activity
D7A46_RS14355	COG2873	o-acetylhomoserine
D7A46_RS14360	COG0488	(ABC) transporter
D7A46_RS14445	COG0833	amino acid
D7A46_RS14490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
D7A46_RS14495	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
D7A46_RS14510	COG2226	methyltransferase
D7A46_RS14560	COG0069	glutamate synthase activity
D7A46_RS14560	COG0070	glutamate synthase
D7A46_RS14560	COG0067	glutamate synthase
D7A46_RS14565	COG0493	'glutamate synthase
D7A46_RS14575	COG1704	LemA family
D7A46_RS14580	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
D7A46_RS14600	COG3307	-O-antigen
D7A46_RS14620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
D7A46_RS14635	COG0194	GDP metabolic process
D7A46_RS14685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
D7A46_RS14705	COG5380	lipid catabolic process
D7A46_RS14710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
D7A46_RS14735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
D7A46_RS14740	COG0277	FAD linked oxidase domain protein
D7A46_RS14750	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
D7A46_RS14755	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7A46_RS14770	COG1289	transmembrane transporter activity
D7A46_RS14780	COG0628	permease
D7A46_RS14785	COG1192	Involved in chromosome partitioning
D7A46_RS14815	COG0833	amino acid
D7A46_RS14820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
D7A46_RS14825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
D7A46_RS14835	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS14875	COG0583	DNA-binding transcription factor activity
D7A46_RS14920	COG0517	IMP dehydrogenase activity
D7A46_RS14925	COG1983	PspC domain protein
D7A46_RS14935	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS14950	COG0408	coproporphyrinogen oxidase activity
D7A46_RS14970	COG0513	Belongs to the DEAD box helicase family
D7A46_RS14980	COG1127	ABC transporter
D7A46_RS14985	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
D7A46_RS14995	COG2854	intermembrane phospholipid transfer
D7A46_RS15005	COG0598	Magnesium transport protein CorA
D7A46_RS15015	COG0494	nUDIX hydrolase
D7A46_RS15020	COG1040	competence protein
D7A46_RS15025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
D7A46_RS15045	COG1946	Acyl-CoA thioesterase
D7A46_RS15050	COG1301	dicarboxylic acid transport
D7A46_RS15065	COG1959	2 iron, 2 sulfur cluster binding
D7A46_RS15070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7A46_RS15070	COG1017	nitric oxide dioxygenase activity
D7A46_RS15075	COG0433	COG0433 Predicted ATPase
D7A46_RS15080	COG0626	cystathionine gamma-synthase activity
D7A46_RS15235	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS15240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
D7A46_RS15270	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
D7A46_RS15275	COG0339	signal peptide processing
D7A46_RS15280	COG0557	exoribonuclease II activity
D7A46_RS15325	COG0179	Fumarylacetoacetate (FAA) hydrolase
D7A46_RS15330	COG2169	Transcriptional regulator
D7A46_RS15335	COG0697	spore germination
D7A46_RS15340	COG1295	ribonuclease BN
D7A46_RS15375	COG1702	phosphate starvation-inducible protein PhoH
D7A46_RS15385	COG0739	heme binding
D7A46_RS15385	COG0741	lytic transglycosylase activity
D7A46_RS15385	COG1196	nuclear chromosome segregation
D7A46_RS15415	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
D7A46_RS15420	COG1183	phosphatidylcholine synthase activity
D7A46_RS15465	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS15470	COG1309	transcriptional regulator
D7A46_RS15485	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
D7A46_RS15490	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS15510	COG2969	positive regulation of protein catabolic process
D7A46_RS15520	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
D7A46_RS15535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
D7A46_RS15540	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
D7A46_RS15560	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
D7A46_RS15570	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
D7A46_RS15575	COG1408	metallophosphoesterase
D7A46_RS15585	COG2199	diguanylate cyclase activity
D7A46_RS15645	COG1607	acyl-coa hydrolase
D7A46_RS15675	COG2350	Protein conserved in bacteria
D7A46_RS15685	COG0613	PHP domain protein
D7A46_RS15690	COG3781	membrane
D7A46_RS15700	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
D7A46_RS15705	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
D7A46_RS15715	COG1862	Preprotein translocase
D7A46_RS15745	COG2205	protein histidine kinase activity
D7A46_RS15750	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
D7A46_RS15770	COG0726	polysaccharide deacetylase
D7A46_RS15775	COG0463	Glycosyl transferase, family 2
D7A46_RS15780	COG0438	transferase activity, transferring glycosyl groups
D7A46_RS15845	COG0625	glutathione transferase activity
D7A46_RS15850	COG0583	DNA-binding transcription factor activity
D7A46_RS15855	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS15860	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS15870	COG2205	protein histidine kinase activity
D7A46_RS15875	COG0745	RESPONSE REGULATOR receiver
D7A46_RS15880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
D7A46_RS15900	COG2096	Adenosyltransferase
D7A46_RS15950	COG0285	dihydrofolate synthase activity
D7A46_RS15970	COG0450	alkyl hydroperoxide reductase
D7A46_RS15985	COG0477	Major facilitator Superfamily
D7A46_RS15990	COG1272	protein, Hemolysin III
D7A46_RS16020	COG0183	Belongs to the thiolase family
D7A46_RS16025	COG2207	Transcriptional regulator
D7A46_RS16045	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_RS16065	COG0183	Belongs to the thiolase family
D7A46_RS16075	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
D7A46_RS16075	COG2885	chlorophyll binding
D7A46_RS16085	COG1690	Belongs to the RtcB family
D7A46_RS16090	COG0833	amino acid
D7A46_RS16100	COG2233	PERMEase
D7A46_RS16105	COG1217	gtp-binding protein TYPA
D7A46_RS16130	COG2094	Belongs to the DNA glycosylase MPG family
D7A46_RS16135	COG4772	TonB-dependent receptor
D7A46_RS16150	COG1902	pentaerythritol trinitrate reductase activity
D7A46_RS16165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
D7A46_RS16170	COG0354	folic acid binding
D7A46_RS16180	COG3189	MarR family transcriptional regulator
D7A46_RS16185	COG2824	Alkylphosphonate utilization operon protein PhnA
D7A46_RS16190	COG3422	double-strand break repair
D7A46_RS16230	COG0840	transmembrane signaling receptor activity
D7A46_RS16250	COG5510	response to toxic substance
D7A46_RS16260	COG2832	Protein of unknown function (DUF454)
D7A46_RS16265	COG1376	ErfK ybiS ycfS ynhG family protein
D7A46_RS16305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
D7A46_RS16315	COG1289	transmembrane transporter activity
D7A46_RS16320	COG2814	Major facilitator Superfamily
D7A46_RS16340	COG1115	amino acid carrier protein
D7A46_RS16345	COG1752	Esterase of the alpha-beta hydrolase superfamily
D7A46_RS16350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
D7A46_RS16355	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
D7A46_RS16395	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D7A46_RS16405	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
D7A46_RS16410	COG1077	Cell shape determining protein MreB Mrl
D7A46_RS16415	COG1792	Involved in formation and maintenance of cell shape
D7A46_RS16420	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
D7A46_RS16425	COG0424	maF-like protein
D7A46_RS16430	COG1530	ribonuclease E activity
D7A46_RS16440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7A46_RS16450	COG0560	Phosphoserine phosphatase
D7A46_RS16460	COG2249	NAD(P)H dehydrogenase (quinone) activity
D7A46_RS16485	COG2207	Transcriptional regulator
D7A46_RS16505	COG1113	amino acid transport
D7A46_RS16510	COG2828	Protein conserved in bacteria
D7A46_RS16515	COG0142	geranyltranstransferase activity
D7A46_RS16520	COG2315	Protein conserved in bacteria
D7A46_RS16535	COG1752	Esterase of the alpha-beta hydrolase superfamily
D7A46_RS16555	COG2194	sulfuric ester hydrolase activity
D7A46_RS16560	COG0745	RESPONSE REGULATOR receiver
D7A46_RS16565	COG0642	Histidine kinase
D7A46_RS16575	COG0004	ammonium transporteR
D7A46_RS16585	COG0583	DNA-binding transcription factor activity
D7A46_RS16605	COG0525	valine-tRNA ligase activity
D7A46_RS16615	COG1028	Short-chain dehydrogenase reductase Sdr
D7A46_RS16625	COG0393	Putative heavy-metal-binding
D7A46_RS16630	COG0393	Putative heavy-metal-binding
D7A46_RS16635	COG1538	Outer membrane efflux protein
D7A46_RS16645	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_RS16650	COG0671	phosphoesterase, PA-phosphatase related
D7A46_RS16680	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
D7A46_RS16695	COG1648	precorrin-2 dehydrogenase activity
D7A46_RS16695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
D7A46_RS16700	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
D7A46_RS16705	COG1733	regulation of RNA biosynthetic process
D7A46_RS16715	COG0531	amino acid
D7A46_RS16730	COG0321	lipoyl(octanoyl) transferase activity
D7A46_RS16735	COG2921	Belongs to the UPF0250 family
D7A46_RS16780	COG2009	succinate dehydrogenase
D7A46_RS16785	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
D7A46_RS16790	COG1053	succinate dehydrogenase
D7A46_RS16795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
D7A46_RS16820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7A46_RS16840	COG2354	Protein conserved in bacteria
D7A46_RS16845	COG2321	neutral zinc metallopeptidase
D7A46_RS16895	COG2843	Capsule synthesis protein
D7A46_RS16910	COG0589	response to stress
D7A46_RS16930	COG0505	Belongs to the CarA family
D7A46_RS16955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
D7A46_RS16960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
D7A46_RS17010	COG0477	Major facilitator Superfamily
D7A46_RS17015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
D7A46_RS17030	COG1597	lipid kinase activity
D7A46_RS17035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
D7A46_RS17065	COG0584	glycerophosphoryl diester phosphodiesterase
D7A46_RS17085	COG0741	lytic transglycosylase activity
D7A46_RS17110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
D7A46_RS17125	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7A46_RS17155	COG0778	Nitroreductase
D7A46_RS17170	COG1929	Belongs to the glycerate kinase type-1 family
D7A46_RS17175	COG0243	molybdopterin cofactor binding
D7A46_RS17180	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
D7A46_RS17185	COG3339	Conserved Protein
D7A46_RS17195	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
D7A46_RS17210	COG1113	amino acid transport
D7A46_RS17220	COG0019	diaminopimelate decarboxylase activity
D7A46_RS17230	COG1280	lysine exporter protein (LysE YggA)
D7A46_RS17235	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
D7A46_RS17265	COG0463	Glycosyl transferase, family 2
D7A46_RS17285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_RS17315	COG4591	ABC-type transport system involved in lipoprotein release permease component
D7A46_RS17320	COG1136	(ABC) transporter
D7A46_RS17325	COG0658	competence protein
D7A46_RS17325	COG2333	competence protein COMEC
D7A46_RS17335	COG0616	signal peptide processing
D7A46_RS17335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
D7A46_RS17340	COG0596	Alpha beta hydrolase
D7A46_RS17345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
D7A46_RS17355	COG0628	permease
D7A46_RS17390	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
D7A46_RS17410	COG0823	Involved in the tonB-independent uptake of proteins
D7A46_RS17430	COG0824	Thioesterase
D7A46_RS17435	COG1473	amidohydrolase
D7A46_RS17455	COG0047	phosphoribosylformylglycinamidine synthase activity
D7A46_RS17455	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
D7A46_RS17460	COG2814	Major facilitator Superfamily
D7A46_RS17470	COG1024	Enoyl-CoA hydratase
D7A46_RS17475	COG1056	cytidyltransferase-related domain
D7A46_RS17475	COG1051	belongs to the nudix hydrolase family
D7A46_RS17485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D7A46_RS17500	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
D7A46_RS17515	COG4625	pathogenesis
D7A46_RS17520	COG0583	DNA-binding transcription factor activity
D7A46_RS17525	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
D7A46_RS17530	COG4208	sulfate ABC transporter
D7A46_RS17535	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
D7A46_RS17545	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
D7A46_RS17550	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
D7A46_RS17555	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
D7A46_RS17575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D7A46_RS17590	COG0681	Belongs to the peptidase S26 family
D7A46_RS17605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
D7A46_RS17615	COG1381	Involved in DNA repair and RecF pathway recombination
D7A46_RS17620	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
D7A46_RS17630	COG4221	oxidoreductase activity
D7A46_RS17660	COG0436	Aminotransferase
D7A46_RS17680	COG0556	nucleotide-excision repair
D7A46_RS17735	COG2070	2-Nitropropane dioxygenase
D7A46_RS17765	COG1215	transferase activity, transferring glycosyl groups
D7A46_RS17780	COG0415	Belongs to the DNA photolyase family
D7A46_RS17790	COG1252	NADH dehydrogenase
D7A46_RS17795	COG1686	Belongs to the peptidase S11 family
D7A46_RS17810	COG1187	pseudouridine synthase activity
D7A46_RS17835	COG0477	Major facilitator Superfamily
D7A46_RS17840	COG0583	DNA-binding transcription factor activity
D7A46_RS17845	COG1823	symporter activity
D7A46_RS17855	COG0612	Peptidase, M16
D7A46_RS17880	COG0352	thiamine-phosphate diphosphorylase activity
D7A46_RS17915	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
D7A46_RS17930	COG1309	transcriptional regulator
D7A46_RS17940	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
D7A46_RS17945	COG0076	glutamate decarboxylase activity
D7A46_RS17955	COG1522	sequence-specific DNA binding
D7A46_RS17960	COG3961	Belongs to the TPP enzyme family
D7A46_RS17965	COG1113	amino acid transport
D7A46_RS17970	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
D7A46_RS17975	COG0573	inorganic phosphate transmembrane transporter activity
D7A46_RS17985	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
D7A46_RS17990	COG0616	signal peptide processing
D7A46_RS18000	COG3328	transposase activity
D7A46_RS18030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
D7A46_RS18035	COG1686	Belongs to the peptidase S11 family
D7A46_RS18060	COG0583	DNA-binding transcription factor activity
D7A46_RS18065	COG1067	ATP-dependent peptidase activity
D7A46_RS18110	COG1966	Carbon starvation protein
D7A46_RS18115	COG2879	small protein
D7A46_RS18150	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
D7A46_RS18150	COG2508	Transcriptional regulator
D7A46_RS18170	COG1113	amino acid transport
D7A46_RS18175	COG0583	DNA-binding transcription factor activity
D7A46_RS18180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_RS18185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
D7A46_RS18195	COG1012	belongs to the aldehyde dehydrogenase family
D7A46_RS18200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
D7A46_RS18205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
D7A46_RS18205	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
D7A46_RS18240	COG2814	Major facilitator Superfamily
D7A46_RS18245	COG4948	Mandelate Racemase Muconate Lactonizing
D7A46_RS18255	COG1309	transcriptional regulator
D7A46_RS18275	COG1741	Belongs to the pirin family
D7A46_RS18285	COG2964	Protein conserved in bacteria
D7A46_RS18300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7A46_RS18305	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
D7A46_RS18310	COG4605	iron ion homeostasis
D7A46_RS18315	COG4604	ABC transporter, ATP-binding protein
D7A46_RS18320	COG4607	ABC-type enterochelin transport system periplasmic component
D7A46_RS18325	COG4774	siderophore transport
D7A46_RS18335	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
D7A46_RS18340	COG1021	2,3-dihydroxybenzoate-AMP ligase
D7A46_RS18345	COG1535	isochorismatase
D7A46_RS18345	COG3433	isochorismatase activity
D7A46_RS18360	COG1132	(ABC) transporter
D7A46_RS18365	COG1132	(ABC) transporter
D7A46_RS18370	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
D7A46_RS18380	COG1169	isochorismate synthase
D7A46_RS18395	COG3739	integral membrane protein
D7A46_RS18420	COG0302	gtp cyclohydrolase
D7A46_RS18430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
D7A46_RS18460	COG0308	aminopeptidase N
D7A46_RS18465	COG0512	Glutamine amidotransferase of anthranilate synthase
D7A46_RS18480	COG0174	glutamine synthetase
D7A46_RS18490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
D7A46_RS18525	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
D7A46_RS18530	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
D7A46_RS18535	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
D7A46_RS18555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
D7A46_RS18560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
D7A46_RS18565	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
D7A46_RS18580	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS18585	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
D7A46_RS18590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
D7A46_RS18600	COG2223	nitrite transmembrane transporter activity
D7A46_RS18610	COG0024	Methionine aminopeptidase
D7A46_RS18615	COG0052	Belongs to the universal ribosomal protein uS2 family
D7A46_RS18630	COG2207	Transcriptional regulator
D7A46_RS18655	COG2951	lytic endotransglycosylase activity
D7A46_RS18660	COG0772	Belongs to the SEDS family
D7A46_RS18675	COG0842	Transport permease protein
D7A46_RS18680	COG1131	(ABC) transporter
D7A46_RS18725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
D7A46_RS18740	COG4215	(ABC) transporter
D7A46_RS18745	COG4160	amino acid transport
D7A46_RS18750	COG4598	ABC transporter
D7A46_RS18760	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
D7A46_RS18765	COG0826	peptidase U32
D7A46_RS18770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
D7A46_RS18785	COG1720	tRNA m6t6A37 methyltransferase activity
D7A46_RS18795	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
D7A46_RS18810	COG0642	Histidine kinase
D7A46_RS18820	COG0494	nUDIX hydrolase
D7A46_RS18830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
D7A46_RS18835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
D7A46_RS18840	COG3139	Protein of unknown function (DUF1315)
D7A46_RS18845	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
D7A46_RS18855	COG1301	dicarboxylic acid transport
D7A46_RS18860	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS18865	COG2819	hydrolase of the alpha beta superfamily
D7A46_RS18875	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
D7A46_RS18885	COG2195	Cleaves the N-terminal amino acid of tripeptides
D7A46_RS18890	COG1234	tRNA 3'-trailer cleavage
D7A46_RS18920	COG2363	Small membrane protein
D7A46_RS18940	COG0513	Belongs to the DEAD box helicase family
D7A46_RS18950	COG0778	Nitroreductase
D7A46_RS18980	COG1286	toxin biosynthetic process
D7A46_RS19005	COG4783	chaperone-mediated protein folding
D7A46_RS19010	COG1610	YqeY-like protein
D7A46_RS19105	COG3111	PFAM Bacterial OB fold (BOF) protein
D7A46_RS19130	COG3243	poly(R)-hydroxyalkanoic acid synthase
D7A46_RS19135	COG0786	glutamate:sodium symporter activity
D7A46_RS19145	COG2186	Transcriptional regulator
D7A46_RS19195	COG0477	Major facilitator Superfamily
D7A46_RS19225	COG2985	domain, Protein
D7A46_RS19235	COG2995	paraquat-inducible protein a
D7A46_RS19240	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
D7A46_RS19240	COG3008	intermembrane lipid transfer
D7A46_RS19265	COG0482	sulfurtransferase activity
D7A46_RS19280	COG0488	(ABC) transporter
D7A46_RS19285	COG3173	Aminoglycoside phosphotransferase
D7A46_RS19295	COG2433	Pfam Transposase IS66
D7A46_RS19335	COG1301	dicarboxylic acid transport
D7A46_RS19345	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
D7A46_RS19350	COG2011	ABC-type metal ion transport system permease component
D7A46_RS19355	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
D7A46_RS19360	COG1464	Belongs to the NlpA lipoprotein family
D7A46_RS19365	COG0151	Belongs to the GarS family
D7A46_RS19370	COG0138	bifunctional purine biosynthesis protein purh
D7A46_RS19375	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
D7A46_RS19405	COG2308	Evidence 4 Homologs of previously reported genes of
D7A46_RS19415	COG1305	Transglutaminase-like
D7A46_RS19425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
D7A46_RS19430	COG0305	Participates in initiation and elongation during chromosome replication
D7A46_RS19455	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
D7A46_RS19465	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
D7A46_RS19470	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
D7A46_RS19495	COG0726	polysaccharide deacetylase
D7A46_RS19495	COG1649	PFAM Uncharacterised BCR, COG1649
D7A46_RS19500	COG1215	transferase activity, transferring glycosyl groups
D7A46_RS19505	COG3658	cytochrome
D7A46_RS19515	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
D7A46_RS19535	COG0583	DNA-binding transcription factor activity
D7A46_RS19555	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
D7A46_RS19560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
D7A46_RS19575	COG1960	acyl-CoA dehydrogenase activity
D7A46_RS19580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
D7A46_RS19585	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
D7A46_RS19610	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
D7A46_RS19615	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system