locus-tag	class	description
AN158_RS00005	COG0583	DNA-binding transcription factor activity
AN158_RS00010	COG0183	Belongs to the thiolase family
AN158_RS00015	COG2031	fatty acid transporter
AN158_RS00030	COG0583	DNA-binding transcription factor activity
AN158_RS00045	COG2610	gluconate transmembrane transporter activity
AN158_RS00050	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS00055	COG2207	Transcriptional regulator
AN158_RS00070	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS00095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN158_RS00095	COG0543	2 iron, 2 sulfur cluster binding
AN158_RS00100	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AN158_RS00105	COG4638	Rieske (2fe-2S)
AN158_RS00115	COG0725	ABC transporter, periplasmic molybdate-binding protein
AN158_RS00120	COG4149	molybdate abc transporter
AN158_RS00125	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AN158_RS00130	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS00135	COG3433	isochorismatase activity
AN158_RS00135	COG1535	isochorismatase
AN158_RS00195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN158_RS00210	COG0753	catalase activity
AN158_RS00220	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AN158_RS00260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN158_RS00265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN158_RS00270	COG0745	RESPONSE REGULATOR receiver
AN158_RS00275	COG2205	protein histidine kinase activity
AN158_RS00285	COG2207	Transcriptional regulator
AN158_RS00300	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS00305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AN158_RS00310	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN158_RS00315	COG2851	Citrate transporter
AN158_RS00320	COG1414	Transcriptional regulator
AN158_RS00330	COG0583	DNA-binding transcription factor activity
AN158_RS00340	COG0477	Major facilitator Superfamily
AN158_RS00355	COG2350	Protein conserved in bacteria
AN158_RS00405	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AN158_RS00455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AN158_RS00475	COG1120	ATPase activity
AN158_RS00480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN158_RS00490	COG1064	alcohol dehydrogenase
AN158_RS00495	COG2207	Transcriptional regulator
AN158_RS00500	COG2084	Dehydrogenase
AN158_RS00510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN158_RS00515	COG0583	DNA-binding transcription factor activity
AN158_RS00525	COG0129	dihydroxy-acid dehydratase activity
AN158_RS00530	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS00545	COG1566	PFAM secretion protein HlyD family protein
AN158_RS00560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AN158_RS00590	COG0583	DNA-binding transcription factor activity
AN158_RS00605	COG2188	Transcriptional regulator
AN158_RS00670	COG1473	amidohydrolase
AN158_RS00680	COG0475	glutathione-regulated potassium exporter activity
AN158_RS00680	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN158_RS00690	COG0583	DNA-binding transcription factor activity
AN158_RS00695	COG1335	isochorismatase
AN158_RS00705	COG1309	transcriptional regulator
AN158_RS00730	COG0789	Transcriptional regulator
AN158_RS00760	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS00780	COG2186	Transcriptional regulator
AN158_RS00790	COG0583	DNA-binding transcription factor activity
AN158_RS00795	COG4948	Mandelate Racemase Muconate Lactonizing
AN158_RS00800	COG4829	muconolactone delta-isomerase
AN158_RS00810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN158_RS00815	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN158_RS00820	COG0183	Belongs to the thiolase family
AN158_RS00825	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AN158_RS00830	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS00840	COG3733	amine oxidase
AN158_RS00850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN158_RS00860	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS00870	COG4638	Rieske (2fe-2S)
AN158_RS00890	COG0154	amidase activity
AN158_RS00900	COG2814	Major facilitator Superfamily
AN158_RS00930	COG0583	DNA-binding transcription factor activity
AN158_RS00935	COG1414	Transcriptional regulator
AN158_RS00950	COG2391	methyltransferase activity
AN158_RS00960	COG4993	Dehydrogenase
AN158_RS00965	COG3659	wide pore channel activity
AN158_RS00970	COG3420	alginic acid biosynthetic process
AN158_RS00975	COG0710	3-dehydroquinate dehydratase activity
AN158_RS00980	COG3485	protocatechuate 3,4-dioxygenase
AN158_RS00985	COG3485	protocatechuate 3,4-dioxygenase
AN158_RS00990	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN158_RS00995	COG2271	Major facilitator Superfamily
AN158_RS01000	COG0596	Alpha beta hydrolase
AN158_RS01005	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AN158_RS01010	COG0183	Belongs to the thiolase family
AN158_RS01015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN158_RS01020	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN158_RS01030	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AN158_RS01035	COG2323	membrane
AN158_RS01080	COG1902	pentaerythritol trinitrate reductase activity
AN158_RS01080	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN158_RS01105	COG0542	response to heat
AN158_RS01110	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AN158_RS01140	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AN158_RS01145	COG0569	domain protein
AN158_RS01150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN158_RS01165	COG4774	siderophore transport
AN158_RS01170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN158_RS01180	COG1585	Membrane protein implicated in regulation of membrane protease activity
AN158_RS01195	COG1294	oxidase, subunit
AN158_RS01200	COG4890	Cyd operon protein YbgT
AN158_RS01210	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AN158_RS01220	COG0552	protein localization to endoplasmic reticulum
AN158_RS01245	COG0517	IMP dehydrogenase activity
AN158_RS01245	COG0516	GMP reductase activity
AN158_RS01250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN158_RS01255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AN158_RS01265	COG0583	DNA-binding transcription factor activity
AN158_RS01270	COG0024	Methionine aminopeptidase
AN158_RS01300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN158_RS01300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN158_RS01305	COG1105	Belongs to the carbohydrate kinase PfkB family
AN158_RS01310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN158_RS01310	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AN158_RS01310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN158_RS01330	COG3300	MHYT domain
AN158_RS01330	COG5001	Diguanylate cyclase
AN158_RS01345	COG2135	peptidase activity
AN158_RS01350	COG0659	secondary active sulfate transmembrane transporter activity
AN158_RS01365	COG1113	amino acid transport
AN158_RS01375	COG1522	sequence-specific DNA binding
AN158_RS01400	COG1011	Hydrolase
AN158_RS01405	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AN158_RS01415	COG2137	regulation of response to DNA damage stimulus
AN158_RS01430	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN158_RS01465	COG0575	Belongs to the CDS family
AN158_RS01470	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AN158_RS01490	COG3852	Histidine kinase
AN158_RS01495	COG2204	response regulator
AN158_RS01550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AN158_RS01555	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AN158_RS01575	COG0697	spore germination
AN158_RS01580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN158_RS01590	COG0303	'Molybdopterin
AN158_RS01595	COG0521	Mo-molybdopterin cofactor biosynthetic process
AN158_RS01595	COG0315	cyclic pyranopterin monophosphate synthase activity
AN158_RS01610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AN158_RS01615	COG0243	molybdopterin cofactor binding
AN158_RS01625	COG0243	molybdopterin cofactor binding
AN158_RS01630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN158_RS01635	COG2146	nitrite reductase [NAD(P)H] activity
AN158_RS01635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN158_RS01645	COG0745	RESPONSE REGULATOR receiver
AN158_RS01650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN158_RS01650	COG1116	anion transmembrane transporter activity
AN158_RS01665	COG0511	ligase activity, forming carbon-carbon bonds
AN158_RS01680	COG2814	Major facilitator Superfamily
AN158_RS01700	COG0069	glutamate synthase activity
AN158_RS01720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN158_RS01730	COG1454	alcohol dehydrogenase
AN158_RS01735	COG0824	Thioesterase
AN158_RS01745	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AN158_RS01760	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN158_RS01765	COG2030	dehydratase
AN158_RS01775	COG0183	Belongs to the thiolase family
AN158_RS01785	COG0583	DNA-binding transcription factor activity
AN158_RS01790	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AN158_RS01800	COG1522	sequence-specific DNA binding
AN158_RS01805	COG3135	benzoate transporter
AN158_RS01815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AN158_RS01835	COG0589	response to stress
AN158_RS01840	COG0488	(ABC) transporter
AN158_RS01860	COG4773	Receptor
AN158_RS01890	COG0668	transmembrane transport
AN158_RS01915	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AN158_RS01930	COG1605	Chorismate mutase
AN158_RS01970	COG0308	aminopeptidase N
AN158_RS01990	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AN158_RS02000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AN158_RS02005	COG1454	alcohol dehydrogenase
AN158_RS02025	COG0531	amino acid
AN158_RS02030	COG4303	Ethanolamine ammonia lyase large subunit
AN158_RS02035	COG4302	ethanolamine ammonia-lyase activity
AN158_RS02040	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AN158_RS02040	COG0519	Catalyzes the synthesis of GMP from XMP
AN158_RS02045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN158_RS02065	COG0697	spore germination
AN158_RS02070	COG1923	regulation of RNA biosynthetic process
AN158_RS02080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AN158_RS02085	COG0802	atpase or kinase
AN158_RS02105	COG1187	pseudouridine synthase activity
AN158_RS02120	COG0583	DNA-binding transcription factor activity
AN158_RS02135	COG2814	Major facilitator Superfamily
AN158_RS02140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN158_RS02165	COG0729	surface antigen
AN158_RS02185	COG0174	glutamine synthetase
AN158_RS02190	COG0745	RESPONSE REGULATOR receiver
AN158_RS02195	COG2205	protein histidine kinase activity
AN158_RS02205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AN158_RS02210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AN158_RS02235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN158_RS02240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN158_RS02245	COG1960	acyl-CoA dehydrogenase activity
AN158_RS02275	COG0583	DNA-binding transcription factor activity
AN158_RS02290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN158_RS02300	COG3658	cytochrome
AN158_RS02305	COG1215	transferase activity, transferring glycosyl groups
AN158_RS02310	COG1649	PFAM Uncharacterised BCR, COG1649
AN158_RS02310	COG0726	polysaccharide deacetylase
AN158_RS02335	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AN158_RS02340	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AN158_RS02350	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AN158_RS02375	COG0305	Participates in initiation and elongation during chromosome replication
AN158_RS02380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN158_RS02390	COG1305	Transglutaminase-like
AN158_RS02400	COG2308	Evidence 4 Homologs of previously reported genes of
AN158_RS02430	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AN158_RS02435	COG0138	bifunctional purine biosynthesis protein purh
AN158_RS02440	COG0151	Belongs to the GarS family
AN158_RS02445	COG1464	Belongs to the NlpA lipoprotein family
AN158_RS02450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AN158_RS02455	COG2011	ABC-type metal ion transport system permease component
AN158_RS02460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN158_RS02470	COG1301	dicarboxylic acid transport
AN158_RS02500	COG1794	racemase activity, acting on amino acids and derivatives
AN158_RS02510	COG3008	intermembrane lipid transfer
AN158_RS02510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AN158_RS02515	COG2995	paraquat-inducible protein a
AN158_RS02525	COG2985	domain, Protein
AN158_RS02560	COG0477	Major facilitator Superfamily
AN158_RS02610	COG2186	Transcriptional regulator
AN158_RS02620	COG0786	glutamate:sodium symporter activity
AN158_RS02625	COG3243	poly(R)-hydroxyalkanoic acid synthase
AN158_RS02650	COG3111	PFAM Bacterial OB fold (BOF) protein
AN158_RS02750	COG1610	YqeY-like protein
AN158_RS02755	COG4783	chaperone-mediated protein folding
AN158_RS02780	COG1286	toxin biosynthetic process
AN158_RS02810	COG0778	Nitroreductase
AN158_RS02820	COG0513	Belongs to the DEAD box helicase family
AN158_RS02840	COG2363	Small membrane protein
AN158_RS02870	COG1234	tRNA 3'-trailer cleavage
AN158_RS02875	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN158_RS02885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AN158_RS02895	COG2819	hydrolase of the alpha beta superfamily
AN158_RS02900	COG1960	acyl-CoA dehydrogenase activity
AN158_RS02905	COG1301	dicarboxylic acid transport
AN158_RS02910	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AN158_RS02915	COG3139	Protein of unknown function (DUF1315)
AN158_RS02920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN158_RS02925	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN158_RS02935	COG0494	nUDIX hydrolase
AN158_RS02945	COG0642	Histidine kinase
AN158_RS02960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN158_RS02970	COG1720	tRNA m6t6A37 methyltransferase activity
AN158_RS02985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN158_RS02990	COG0826	peptidase U32
AN158_RS02995	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AN158_RS03005	COG4598	ABC transporter
AN158_RS03010	COG4160	amino acid transport
AN158_RS03015	COG4215	(ABC) transporter
AN158_RS03030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN158_RS03070	COG1131	(ABC) transporter
AN158_RS03075	COG0842	Transport permease protein
AN158_RS03090	COG0772	Belongs to the SEDS family
AN158_RS03095	COG2951	lytic endotransglycosylase activity
AN158_RS03120	COG2207	Transcriptional regulator
AN158_RS03135	COG0052	Belongs to the universal ribosomal protein uS2 family
AN158_RS03140	COG0024	Methionine aminopeptidase
AN158_RS03150	COG2223	nitrite transmembrane transporter activity
AN158_RS03165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN158_RS03170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AN158_RS03175	COG1960	acyl-CoA dehydrogenase activity
AN158_RS03190	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AN158_RS03195	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AN158_RS03200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AN158_RS03220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN158_RS03225	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AN158_RS03230	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AN158_RS03265	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AN158_RS03275	COG0174	glutamine synthetase
AN158_RS03290	COG0512	Glutamine amidotransferase of anthranilate synthase
AN158_RS03295	COG0308	aminopeptidase N
AN158_RS03315	COG2840	Smr protein MutS2
AN158_RS03325	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AN158_RS03335	COG0302	gtp cyclohydrolase
AN158_RS03355	COG3739	integral membrane protein
AN158_RS03375	COG2977	Belongs to the P-Pant transferase superfamily
AN158_RS03380	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AN158_RS03385	COG1132	(ABC) transporter
AN158_RS03390	COG1132	(ABC) transporter
AN158_RS03405	COG1535	isochorismatase
AN158_RS03405	COG3433	isochorismatase activity
AN158_RS03410	COG1021	2,3-dihydroxybenzoate-AMP ligase
AN158_RS03415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN158_RS03425	COG4774	siderophore transport
AN158_RS03430	COG4607	ABC-type enterochelin transport system periplasmic component
AN158_RS03435	COG4604	ABC transporter, ATP-binding protein
AN158_RS03440	COG4605	iron ion homeostasis
AN158_RS03445	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN158_RS03450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN158_RS03465	COG2964	Protein conserved in bacteria
AN158_RS03475	COG1741	Belongs to the pirin family
AN158_RS03495	COG2828	Protein conserved in bacteria
AN158_RS03500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AN158_RS03505	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AN158_RS03510	COG0583	DNA-binding transcription factor activity
AN158_RS03535	COG3659	wide pore channel activity
AN158_RS03550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN158_RS03560	COG0596	Alpha beta hydrolase
AN158_RS03575	COG0583	DNA-binding transcription factor activity
AN158_RS03580	COG1335	isochorismatase
AN158_RS03620	COG2879	small protein
AN158_RS03625	COG1966	Carbon starvation protein
AN158_RS03645	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AN158_RS03670	COG1067	ATP-dependent peptidase activity
AN158_RS03675	COG0583	DNA-binding transcription factor activity
AN158_RS03700	COG1686	Belongs to the peptidase S11 family
AN158_RS03705	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AN158_RS03740	COG0616	signal peptide processing
AN158_RS03745	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN158_RS03755	COG0573	inorganic phosphate transmembrane transporter activity
AN158_RS03760	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AN158_RS03765	COG1113	amino acid transport
AN158_RS03770	COG3961	Belongs to the TPP enzyme family
AN158_RS03775	COG1522	sequence-specific DNA binding
AN158_RS03785	COG0076	glutamate decarboxylase activity
AN158_RS03790	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN158_RS03800	COG1309	transcriptional regulator
AN158_RS03815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN158_RS03850	COG0352	thiamine-phosphate diphosphorylase activity
AN158_RS03875	COG0612	Peptidase, M16
AN158_RS03885	COG1823	symporter activity
AN158_RS03890	COG0583	DNA-binding transcription factor activity
AN158_RS03895	COG0477	Major facilitator Superfamily
AN158_RS03915	COG1187	pseudouridine synthase activity
AN158_RS03930	COG1686	Belongs to the peptidase S11 family
AN158_RS03935	COG1252	NADH dehydrogenase
AN158_RS03945	COG0415	Belongs to the DNA photolyase family
AN158_RS03960	COG1215	transferase activity, transferring glycosyl groups
AN158_RS03990	COG2070	2-Nitropropane dioxygenase
AN158_RS04045	COG0556	nucleotide-excision repair
AN158_RS04065	COG0436	Aminotransferase
AN158_RS04090	COG4221	oxidoreductase activity
AN158_RS04100	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AN158_RS04105	COG1381	Involved in DNA repair and RecF pathway recombination
AN158_RS04115	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AN158_RS04130	COG0681	Belongs to the peptidase S26 family
AN158_RS04145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN158_RS04165	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AN158_RS04170	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN158_RS04175	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AN158_RS04185	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AN158_RS04190	COG4208	sulfate ABC transporter
AN158_RS04195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AN158_RS04200	COG0583	DNA-binding transcription factor activity
AN158_RS04205	COG4625	pathogenesis
AN158_RS04220	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AN158_RS04235	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AN158_RS04245	COG1056	cytidyltransferase-related domain
AN158_RS04245	COG1051	belongs to the nudix hydrolase family
AN158_RS04250	COG1024	Enoyl-CoA hydratase
AN158_RS04265	COG2814	Major facilitator Superfamily
AN158_RS04270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AN158_RS04270	COG0047	phosphoribosylformylglycinamidine synthase activity
AN158_RS04290	COG1473	amidohydrolase
AN158_RS04295	COG0824	Thioesterase
AN158_RS04315	COG0823	Involved in the tonB-independent uptake of proteins
AN158_RS04335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN158_RS04370	COG0628	permease
AN158_RS04380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AN158_RS04385	COG0596	Alpha beta hydrolase
AN158_RS04390	COG0616	signal peptide processing
AN158_RS04390	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AN158_RS04400	COG0658	competence protein
AN158_RS04400	COG2333	competence protein COMEC
AN158_RS04405	COG1136	(ABC) transporter
AN158_RS04410	COG4591	ABC-type transport system involved in lipoprotein release permease component
AN158_RS04440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN158_RS04460	COG0463	Glycosyl transferase, family 2
AN158_RS04490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AN158_RS04495	COG1280	lysine exporter protein (LysE YggA)
AN158_RS04505	COG0019	diaminopimelate decarboxylase activity
AN158_RS04515	COG1113	amino acid transport
AN158_RS04530	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AN158_RS04540	COG3339	Conserved Protein
AN158_RS04545	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AN158_RS04550	COG0243	molybdopterin cofactor binding
AN158_RS04555	COG1929	Belongs to the glycerate kinase type-1 family
AN158_RS04570	COG0778	Nitroreductase
AN158_RS04590	COG3811	Belongs to the UPF0386 family
AN158_RS04600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN158_RS04615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN158_RS04635	COG0741	lytic transglycosylase activity
AN158_RS04655	COG0584	glycerophosphoryl diester phosphodiesterase
AN158_RS04660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN158_RS04685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AN158_RS04690	COG1597	lipid kinase activity
AN158_RS04705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AN158_RS04710	COG0477	Major facilitator Superfamily
AN158_RS04760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AN158_RS04765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN158_RS04790	COG0505	Belongs to the CarA family
AN158_RS04810	COG0589	response to stress
AN158_RS04825	COG2843	Capsule synthesis protein
AN158_RS04845	COG2321	neutral zinc metallopeptidase
AN158_RS04850	COG2354	Protein conserved in bacteria
AN158_RS04880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN158_RS04895	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AN158_RS04900	COG1053	succinate dehydrogenase
AN158_RS04905	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AN158_RS04910	COG2009	succinate dehydrogenase
AN158_RS04945	COG2921	Belongs to the UPF0250 family
AN158_RS04950	COG0321	lipoyl(octanoyl) transferase activity
AN158_RS04965	COG0531	amino acid
AN158_RS04975	COG1733	regulation of RNA biosynthetic process
AN158_RS04980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AN158_RS04985	COG1648	precorrin-2 dehydrogenase activity
AN158_RS04985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN158_RS05000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AN158_RS05030	COG0671	phosphoesterase, PA-phosphatase related
AN158_RS05035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN158_RS05045	COG1538	Outer membrane efflux protein
AN158_RS05050	COG0393	Putative heavy-metal-binding
AN158_RS05055	COG0393	Putative heavy-metal-binding
AN158_RS05065	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS05075	COG0525	valine-tRNA ligase activity
AN158_RS05110	COG0583	DNA-binding transcription factor activity
AN158_RS05115	COG0004	ammonium transporteR
AN158_RS05125	COG0642	Histidine kinase
AN158_RS05130	COG0745	RESPONSE REGULATOR receiver
AN158_RS05135	COG2194	sulfuric ester hydrolase activity
AN158_RS05155	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN158_RS05170	COG2315	Protein conserved in bacteria
AN158_RS05175	COG0142	geranyltranstransferase activity
AN158_RS05180	COG2828	Protein conserved in bacteria
AN158_RS05185	COG1113	amino acid transport
AN158_RS05205	COG2207	Transcriptional regulator
AN158_RS05230	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN158_RS05240	COG0560	Phosphoserine phosphatase
AN158_RS05250	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN158_RS05260	COG1530	ribonuclease E activity
AN158_RS05265	COG0424	maF-like protein
AN158_RS05270	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AN158_RS05275	COG1792	Involved in formation and maintenance of cell shape
AN158_RS05280	COG1077	Cell shape determining protein MreB Mrl
AN158_RS05285	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN158_RS05295	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN158_RS05320	COG3590	peptidase
AN158_RS05325	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AN158_RS05330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AN158_RS05335	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN158_RS05340	COG1115	amino acid carrier protein
AN158_RS05355	COG2814	Major facilitator Superfamily
AN158_RS05360	COG1289	transmembrane transporter activity
AN158_RS05370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN158_RS05410	COG1376	ErfK ybiS ycfS ynhG family protein
AN158_RS05415	COG2832	Protein of unknown function (DUF454)
AN158_RS05425	COG5510	response to toxic substance
AN158_RS05445	COG0840	transmembrane signaling receptor activity
AN158_RS05485	COG3422	double-strand break repair
AN158_RS05490	COG2824	Alkylphosphonate utilization operon protein PhnA
AN158_RS05495	COG3189	MarR family transcriptional regulator
AN158_RS05505	COG0354	folic acid binding
AN158_RS05510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN158_RS05520	COG0679	Auxin Efflux Carrier
AN158_RS05525	COG1902	pentaerythritol trinitrate reductase activity
AN158_RS05530	COG4772	TonB-dependent receptor
AN158_RS05535	COG2094	Belongs to the DNA glycosylase MPG family
AN158_RS05560	COG1217	gtp-binding protein TYPA
AN158_RS05565	COG2233	PERMEase
AN158_RS05575	COG0833	amino acid
AN158_RS05580	COG1690	Belongs to the RtcB family
AN158_RS05590	COG2885	chlorophyll binding
AN158_RS05590	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AN158_RS05600	COG0183	Belongs to the thiolase family
AN158_RS05620	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN158_RS05640	COG2207	Transcriptional regulator
AN158_RS05645	COG0183	Belongs to the thiolase family
AN158_RS05675	COG1272	protein, Hemolysin III
AN158_RS05680	COG0477	Major facilitator Superfamily
AN158_RS05695	COG0450	alkyl hydroperoxide reductase
AN158_RS05715	COG0285	dihydrofolate synthase activity
AN158_RS05765	COG2096	Adenosyltransferase
AN158_RS05785	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AN158_RS05790	COG0745	RESPONSE REGULATOR receiver
AN158_RS05795	COG2205	protein histidine kinase activity
AN158_RS05805	COG1960	acyl-CoA dehydrogenase activity
AN158_RS05810	COG1960	acyl-CoA dehydrogenase activity
AN158_RS05885	COG0438	transferase activity, transferring glycosyl groups
AN158_RS05890	COG0463	Glycosyl transferase, family 2
AN158_RS05895	COG0726	polysaccharide deacetylase
AN158_RS05920	COG2205	protein histidine kinase activity
AN158_RS05955	COG1862	Preprotein translocase
AN158_RS05965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AN158_RS05970	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AN158_RS05980	COG3781	membrane
AN158_RS05985	COG0613	PHP domain protein
AN158_RS05995	COG2350	Protein conserved in bacteria
AN158_RS06025	COG1607	acyl-coa hydrolase
AN158_RS06085	COG2199	diguanylate cyclase activity
AN158_RS06095	COG1408	metallophosphoesterase
AN158_RS06100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN158_RS06110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AN158_RS06130	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AN158_RS06135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AN158_RS06150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AN158_RS06160	COG2969	positive regulation of protein catabolic process
AN158_RS06180	COG1960	acyl-CoA dehydrogenase activity
AN158_RS06185	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AN158_RS06200	COG1309	transcriptional regulator
AN158_RS06205	COG1960	acyl-CoA dehydrogenase activity
AN158_RS06250	COG1183	phosphatidylcholine synthase activity
AN158_RS06255	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AN158_RS06285	COG1196	nuclear chromosome segregation
AN158_RS06285	COG0741	lytic transglycosylase activity
AN158_RS06285	COG0739	heme binding
AN158_RS06295	COG1702	phosphate starvation-inducible protein PhoH
AN158_RS06330	COG1295	ribonuclease BN
AN158_RS06335	COG0697	spore germination
AN158_RS06340	COG2169	Transcriptional regulator
AN158_RS06345	COG0179	Fumarylacetoacetate (FAA) hydrolase
AN158_RS06390	COG0557	exoribonuclease II activity
AN158_RS06395	COG0339	signal peptide processing
AN158_RS06400	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AN158_RS06430	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AN158_RS06435	COG1960	acyl-CoA dehydrogenase activity
AN158_RS06590	COG0626	cystathionine gamma-synthase activity
AN158_RS06595	COG0433	COG0433 Predicted ATPase
AN158_RS06600	COG1017	nitric oxide dioxygenase activity
AN158_RS06600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN158_RS06605	COG1959	2 iron, 2 sulfur cluster binding
AN158_RS06620	COG1301	dicarboxylic acid transport
AN158_RS06625	COG1946	Acyl-CoA thioesterase
AN158_RS06645	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AN158_RS06650	COG1040	competence protein
AN158_RS06655	COG0494	nUDIX hydrolase
AN158_RS06665	COG0598	Magnesium transport protein CorA
AN158_RS06675	COG2854	intermembrane phospholipid transfer
AN158_RS06685	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AN158_RS06690	COG1127	ABC transporter
AN158_RS06700	COG0513	Belongs to the DEAD box helicase family
AN158_RS06720	COG0408	coproporphyrinogen oxidase activity
AN158_RS06735	COG1960	acyl-CoA dehydrogenase activity
AN158_RS06745	COG1983	PspC domain protein
AN158_RS06750	COG0517	IMP dehydrogenase activity
AN158_RS06800	COG0583	DNA-binding transcription factor activity
AN158_RS06840	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS06850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN158_RS06855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN158_RS06860	COG0833	amino acid
AN158_RS06890	COG1192	Involved in chromosome partitioning
AN158_RS06895	COG0628	permease
AN158_RS06905	COG1289	transmembrane transporter activity
AN158_RS06920	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN158_RS06925	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN158_RS06935	COG0277	FAD linked oxidase domain protein
AN158_RS06940	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN158_RS06965	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AN158_RS06970	COG5380	lipid catabolic process
AN158_RS06990	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AN158_RS07030	COG4969	Belongs to the N-Me-Phe pilin family
AN158_RS07040	COG0194	GDP metabolic process
AN158_RS07050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN158_RS07070	COG3307	-O-antigen
AN158_RS07090	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AN158_RS07095	COG1704	LemA family
AN158_RS07105	COG0493	'glutamate synthase
AN158_RS07110	COG0069	glutamate synthase activity
AN158_RS07110	COG0070	glutamate synthase
AN158_RS07110	COG0067	glutamate synthase
AN158_RS07160	COG2226	methyltransferase
AN158_RS07175	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AN158_RS07180	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AN158_RS07225	COG0833	amino acid
AN158_RS07290	COG0488	(ABC) transporter
AN158_RS07295	COG2873	o-acetylhomoserine
AN158_RS07300	COG4221	oxidoreductase activity
AN158_RS07305	COG0659	secondary active sulfate transmembrane transporter activity
AN158_RS07325	COG0427	acetyl-CoA hydrolase
AN158_RS07355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AN158_RS07375	COG1132	(ABC) transporter
AN158_RS07390	COG2329	Antibiotic biosynthesis monooxygenase
AN158_RS07405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN158_RS07470	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN158_RS07475	COG1733	regulation of RNA biosynthetic process
AN158_RS07505	COG0667	Aldo Keto reductase
AN158_RS07525	COG0583	DNA-binding transcription factor activity
AN158_RS07530	COG2814	Major facilitator Superfamily
AN158_RS07620	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AN158_RS07640	COG1401	restriction endodeoxyribonuclease activity
AN158_RS07680	COG1335	isochorismatase
AN158_RS07690	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS07695	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN158_RS07705	COG1113	amino acid transport
AN158_RS07715	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AN158_RS07730	COG2814	Major facilitator Superfamily
AN158_RS07740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AN158_RS07740	COG0352	thiamine-phosphate diphosphorylase activity
AN158_RS07740	COG0351	phosphomethylpyrimidine kinase
AN158_RS07760	COG1309	transcriptional regulator
AN158_RS07765	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AN158_RS07780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN158_RS07790	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN158_RS07795	COG3162	membrane
AN158_RS07800	COG0784	Response regulator, receiver
AN158_RS07800	COG2205	protein histidine kinase activity
AN158_RS07800	COG2198	Histidine kinase
AN158_RS07825	COG1522	sequence-specific DNA binding
AN158_RS07830	COG1335	isochorismatase
AN158_RS07835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN158_RS07845	COG0668	transmembrane transport
AN158_RS07850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AN158_RS07855	COG1519	Transferase
AN158_RS07860	COG1902	pentaerythritol trinitrate reductase activity
AN158_RS07880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AN158_RS07905	COG0426	domain, Protein
AN158_RS07905	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN158_RS07910	COG4774	siderophore transport
AN158_RS07915	COG2119	membrane
AN158_RS07925	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN158_RS07935	COG4942	peptidase
AN158_RS07950	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AN158_RS07960	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AN158_RS07980	COG0189	ligase activity
AN158_RS08000	COG0708	Exodeoxyribonuclease III
AN158_RS08005	COG1393	Belongs to the ArsC family
AN158_RS08020	COG3706	GGDEF domain
AN158_RS08055	COG2351	hydroxyisourate hydrolase activity
AN158_RS08060	COG2233	PERMEase
AN158_RS08070	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN158_RS08080	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AN158_RS08090	COG3150	esterase
AN158_RS08125	COG2918	glutathione biosynthetic process
AN158_RS08140	COG2733	membrane
AN158_RS08145	COG0436	Aminotransferase
AN158_RS08150	COG0534	Mate efflux family protein
AN158_RS08235	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AN158_RS08240	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AN158_RS08250	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AN158_RS08255	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AN158_RS08260	COG0546	phosphoglycolate phosphatase activity
AN158_RS08270	COG0010	Belongs to the arginase family
AN158_RS08300	COG2188	Transcriptional regulator
AN158_RS08310	COG0523	cobalamin synthesis protein
AN158_RS08320	COG1113	amino acid transport
AN158_RS08330	COG0625	glutathione transferase activity
AN158_RS08350	COG1683	Conserved Protein
AN158_RS08355	COG0534	Mate efflux family protein
AN158_RS08360	COG0385	Bile acid
AN158_RS08365	COG1335	isochorismatase
AN158_RS08370	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN158_RS08390	COG2116	formate transmembrane transporter activity
AN158_RS08395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AN158_RS08400	COG2133	pyrroloquinoline quinone binding
AN158_RS08405	COG2983	Belongs to the UPF0260 family
AN158_RS08425	COG1194	a g-specific adenine glycosylase
AN158_RS08440	COG2818	Glycosylase
AN158_RS08445	COG1064	alcohol dehydrogenase
AN158_RS08450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN158_RS08460	COG0583	DNA-binding transcription factor activity
AN158_RS08465	COG0656	L-ascorbic acid biosynthetic process
AN158_RS08470	COG2814	Major facilitator Superfamily
AN158_RS08505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN158_RS08520	COG2233	PERMEase
AN158_RS08525	COG0583	DNA-binding transcription factor activity
AN158_RS08560	COG0733	neurotransmitter:sodium symporter activity
AN158_RS08605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AN158_RS08610	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AN158_RS08615	COG0596	Alpha beta hydrolase
AN158_RS08640	COG0488	(ABC) transporter
AN158_RS08645	COG0586	Pfam SNARE associated Golgi protein
AN158_RS08655	COG0187	DNA topoisomerase II activity
AN158_RS08665	COG0592	DNA-directed DNA polymerase activity
AN158_RS08690	COG0706	membrane insertase activity
AN158_RS08705	COG1230	cation diffusion facilitator family transporter
AN158_RS08710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN158_RS08730	COG0402	S-adenosylhomocysteine deaminase activity
AN158_RS08740	COG0754	glutathionylspermidine amidase activity
AN158_RS08750	COG0861	Integral membrane protein TerC family
AN158_RS08755	COG0671	phosphoesterase, PA-phosphatase related
AN158_RS08765	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AN158_RS08780	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AN158_RS08785	COG2951	lytic endotransglycosylase activity
AN158_RS08835	COG0657	acetylesterase activity
AN158_RS08840	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AN158_RS08880	COG1047	Peptidyl-prolyl cis-trans
AN158_RS08890	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AN158_RS08895	COG0196	riboflavin kinase activity
AN158_RS08905	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AN158_RS08910	COG1309	transcriptional regulator
AN158_RS08915	COG1116	anion transmembrane transporter activity
AN158_RS08920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN158_RS08925	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN158_RS08930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN158_RS08935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN158_RS08955	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS08960	COG0546	phosphoglycolate phosphatase activity
AN158_RS09015	COG3023	N-Acetylmuramoyl-L-alanine amidase
AN158_RS09020	COG0728	peptidoglycan biosynthetic process
AN158_RS09050	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AN158_RS09100	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AN158_RS09110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN158_RS09125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN158_RS09140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AN158_RS09145	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN158_RS09155	COG2186	Transcriptional regulator
AN158_RS09165	COG0277	FAD linked oxidase domain protein
AN158_RS09170	COG1448	Aminotransferase
AN158_RS09175	COG1802	Transcriptional regulator
AN158_RS09190	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AN158_RS09225	COG1309	transcriptional regulator
AN158_RS09240	COG0564	pseudouridine synthase activity
AN158_RS09280	COG0251	oxidation-reduction process
AN158_RS09285	COG1113	amino acid transport
AN158_RS09290	COG1113	amino acid transport
AN158_RS09310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN158_RS09315	COG1960	acyl-CoA dehydrogenase activity
AN158_RS09320	COG1024	Enoyl-CoA hydratase
AN158_RS09325	COG1024	Enoyl-CoA hydratase
AN158_RS09330	COG0477	Major facilitator Superfamily
AN158_RS09335	COG3916	Acyl-homoserine-lactone synthase
AN158_RS09345	COG2197	response regulator
AN158_RS09355	COG1960	acyl-CoA dehydrogenase activity
AN158_RS09360	COG3321	synthase
AN158_RS09360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN158_RS09360	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AN158_RS09360	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AN158_RS09380	COG2267	carboxylic ester hydrolase activity
AN158_RS09400	COG0271	Belongs to the BolA IbaG family
AN158_RS09410	COG1192	Involved in chromosome partitioning
AN158_RS09425	COG0586	Pfam SNARE associated Golgi protein
AN158_RS09430	COG2259	Doxx family
AN158_RS09435	COG4399	Belongs to the UPF0754 family
AN158_RS09440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AN158_RS09440	COG0519	Catalyzes the synthesis of GMP from XMP
AN158_RS09485	COG0281	malic enzyme
AN158_RS09490	COG2837	iron assimilation
AN158_RS09495	COG1280	lysine exporter protein (LysE YggA)
AN158_RS09500	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN158_RS09505	COG1121	(ABC) transporter
AN158_RS09570	COG0386	Belongs to the glutathione peroxidase family
AN158_RS09585	COG1309	transcriptional regulator
AN158_RS09590	COG0697	spore germination
AN158_RS09600	COG0758	DNA mediated transformation
AN158_RS09635	COG1309	transcriptional regulator
AN158_RS09670	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN158_RS09680	COG0655	NAD(P)H dehydrogenase (quinone) activity
AN158_RS09715	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN158_RS09725	COG0477	Major facilitator Superfamily
AN158_RS09735	COG1253	flavin adenine dinucleotide binding
AN158_RS09745	COG2860	membrane
AN158_RS09750	COG0477	Major facilitator Superfamily
AN158_RS09760	COG0318	PFAM AMP-dependent synthetase and ligase
AN158_RS09775	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AN158_RS09790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN158_RS09800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN158_RS09805	COG0606	chelatase, subunit chli
AN158_RS09815	COG0347	Belongs to the P(II) protein family
AN158_RS09820	COG0004	ammonium transporteR
AN158_RS09830	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN158_RS09830	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN158_RS09870	COG0795	lipopolysaccharide-transporting ATPase activity
AN158_RS09875	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AN158_RS09880	COG0793	Belongs to the peptidase S41A family
AN158_RS09895	COG2197	response regulator
AN158_RS09905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AN158_RS09915	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN158_RS09920	COG4974	Belongs to the 'phage' integrase family
AN158_RS09945	COG0772	Belongs to the SEDS family
AN158_RS09950	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN158_RS09955	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN158_RS09960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AN158_RS09985	COG0697	spore germination
AN158_RS09990	COG1538	Outer membrane efflux protein
AN158_RS10010	COG3275	phosphorelay sensor kinase activity
AN158_RS10020	COG0181	hydroxymethylbilane synthase activity
AN158_RS10065	COG1716	ATPase activity
AN158_RS10070	COG0546	phosphoglycolate phosphatase activity
AN158_RS10170	COG2056	Na+-H+ antiporter family
AN158_RS10185	COG0326	Molecular chaperone. Has ATPase activity
AN158_RS10200	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AN158_RS10270	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AN158_RS10275	COG2169	Transcriptional regulator
AN158_RS10275	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN158_RS10305	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AN158_RS10315	COG0497	DNA recombination
AN158_RS10330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN158_RS10340	COG0237	dephospho-CoA kinase activity
AN158_RS10390	COG0195	Participates in both transcription termination and antitermination
AN158_RS10405	COG1320	monovalent cation:proton antiporter activity
AN158_RS10410	COG2212	antiporter activity
AN158_RS10415	COG1863	multisubunit Na H antiporter MnhE subunit
AN158_RS10420	COG0651	ATP synthesis coupled electron transport
AN158_RS10425	COG1006	Multisubunit Na H antiporter MnhC subunit
AN158_RS10430	COG2111	Na H antiporter
AN158_RS10430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN158_RS10445	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AN158_RS10450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN158_RS10465	COG2226	methyltransferase
AN158_RS10485	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AN158_RS10490	COG1074	ATP-dependent DNA helicase activity
AN158_RS10495	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AN158_RS10500	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN158_RS10515	COG0598	Magnesium transport protein CorA
AN158_RS10520	COG0789	Transcriptional regulator
AN158_RS10525	COG0484	heat shock protein binding
AN158_RS10535	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AN158_RS10540	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN158_RS10540	COG0475	glutathione-regulated potassium exporter activity
AN158_RS10545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AN158_RS10565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN158_RS10575	COG4535	Mg2 and Co2 transporter CorC
AN158_RS10580	COG0425	Belongs to the sulfur carrier protein TusA family
AN158_RS10590	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AN158_RS10590	COG0644	oxidoreductase
AN158_RS10600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AN158_RS10615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN158_RS10620	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AN158_RS10630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AN158_RS10630	COG0493	'glutamate synthase
AN158_RS10655	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AN158_RS10670	COG0534	Mate efflux family protein
AN158_RS10680	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN158_RS10685	COG4221	oxidoreductase activity
AN158_RS10690	COG0583	DNA-binding transcription factor activity
AN158_RS10705	COG0318	PFAM AMP-dependent synthetase and ligase
AN158_RS10710	COG1530	ribonuclease E activity
AN158_RS10720	COG0546	phosphoglycolate phosphatase activity
AN158_RS10725	COG2378	regulation of single-species biofilm formation
AN158_RS10730	COG0625	glutathione transferase activity
AN158_RS10740	COG0583	DNA-binding transcription factor activity
AN158_RS10795	COG0473	3-isopropylmalate dehydrogenase activity
AN158_RS10850	COG1301	dicarboxylic acid transport
AN158_RS10860	COG1560	Kdo2-lipid A biosynthetic process
AN158_RS10865	COG1280	lysine exporter protein (LysE YggA)
AN158_RS10870	COG0488	(ABC) transporter
AN158_RS10875	COG2900	Belongs to the SlyX family
AN158_RS10885	COG1733	regulation of RNA biosynthetic process
AN158_RS10910	COG0210	DNA helicase
AN158_RS10915	COG0724	RNA recognition motif
AN158_RS10935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN158_RS10935	COG4651	solute:proton antiporter activity
AN158_RS10960	COG0788	formyltetrahydrofolate deformylase activity
AN158_RS11060	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AN158_RS11060	COG2813	Specifically methylates the guanine in position
AN158_RS11070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN158_RS11080	COG4774	siderophore transport
AN158_RS11090	COG0740	serine-type endopeptidase activity
AN158_RS11110	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AN158_RS11110	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AN158_RS11115	COG0857	belongs to the CobB CobQ family
AN158_RS11115	COG0280	phosphate acetyltransferase
AN158_RS11120	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AN158_RS11130	COG0800	Aldolase
AN158_RS11140	COG3265	gluconokinase activity
AN158_RS11145	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS11155	COG2267	carboxylic ester hydrolase activity
AN158_RS11170	COG0793	Belongs to the peptidase S41A family
AN158_RS11205	COG1426	Protein conserved in bacteria
AN158_RS11245	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN158_RS11255	COG1162	GTPase activity
AN158_RS11260	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AN158_RS11275	COG1538	Outer membrane efflux protein
AN158_RS11280	COG1136	(ABC) transporter
AN158_RS11280	COG0577	efflux transmembrane transporter activity
AN158_RS11285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN158_RS11310	COG0028	Belongs to the TPP enzyme family
AN158_RS11315	COG0440	acetolactate synthase activity
AN158_RS11345	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AN158_RS11360	COG0084	hydrolase, TatD family'
AN158_RS11370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AN158_RS11375	COG0583	DNA-binding transcription factor activity
AN158_RS11385	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN158_RS11390	COG2814	Major facilitator Superfamily
AN158_RS11400	COG0697	spore germination
AN158_RS11435	COG3622	Belongs to the hyi family
AN158_RS11440	COG2084	Dehydrogenase
AN158_RS11445	COG1024	Enoyl-CoA hydratase
AN158_RS11450	COG0784	Response regulator, receiver
AN158_RS11450	COG2205	protein histidine kinase activity
AN158_RS11450	COG5002	protein histidine kinase activity
AN158_RS11470	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN158_RS11480	COG3956	TIGRFAM MazG family protein
AN158_RS11485	COG1555	photosystem II stabilization
AN158_RS11490	COG0617	tRNA 3'-terminal CCA addition
AN158_RS11495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AN158_RS11515	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN158_RS11520	COG3028	Belongs to the UPF0307 family
AN158_RS11525	COG0318	PFAM AMP-dependent synthetase and ligase
AN158_RS11540	COG0625	glutathione transferase activity
AN158_RS11545	COG1238	metal cluster binding
AN158_RS11585	COG0072	phenylalanine-tRNA ligase activity
AN158_RS11610	COG0248	Ppx GppA phosphatase
AN158_RS11620	COG0037	tRNA processing
AN158_RS11635	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN158_RS11635	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AN158_RS11660	COG1764	response to oxidative stress
AN158_RS11665	COG1846	Transcriptional regulator
AN158_RS11675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN158_RS11735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN158_RS11740	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AN158_RS11745	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AN158_RS11755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AN158_RS11805	COG1214	PFAM Peptidase M22, glycoprotease
AN158_RS11830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AN158_RS11835	COG0561	phosphatase activity
AN158_RS11845	COG2132	Multicopper oxidase
AN158_RS11865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN158_RS11870	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AN158_RS11875	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AN158_RS11905	COG1063	alcohol dehydrogenase
AN158_RS11910	COG0583	DNA-binding transcription factor activity
AN158_RS11915	COG1960	acyl-CoA dehydrogenase activity
AN158_RS11920	COG2814	Major facilitator Superfamily
AN158_RS11925	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AN158_RS11935	COG1053	succinate dehydrogenase
AN158_RS11940	COG0583	DNA-binding transcription factor activity
AN158_RS11955	COG0583	DNA-binding transcription factor activity
AN158_RS11965	COG0583	DNA-binding transcription factor activity
AN158_RS11980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN158_RS12010	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN158_RS12030	COG0745	RESPONSE REGULATOR receiver
AN158_RS12070	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AN158_RS12100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN158_RS12105	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AN158_RS12125	COG0583	DNA-binding transcription factor activity
AN158_RS12145	COG0668	transmembrane transport
AN158_RS12155	COG2081	HI0933 family
AN158_RS12160	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AN158_RS12190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN158_RS12190	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN158_RS12200	COG0489	protein tyrosine kinase activity
AN158_RS12255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN158_RS12265	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AN158_RS12280	COG0730	response to heat
AN158_RS12290	COG1196	nuclear chromosome segregation
AN158_RS12310	COG2223	nitrite transmembrane transporter activity
AN158_RS12315	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AN158_RS12320	COG1877	trehalose-phosphatase activity
AN158_RS12325	COG0596	Alpha beta hydrolase
AN158_RS12325	COG2226	methyltransferase
AN158_RS12325	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AN158_RS12340	COG4106	trans-aconitate 2-methyltransferase activity
AN158_RS12355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AN158_RS12360	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AN158_RS12365	COG0009	L-threonylcarbamoyladenylate synthase
AN158_RS12370	COG3101	peptidyl-lysine hydroxylation
AN158_RS12375	COG1399	metal-binding, possibly nucleic acid-binding protein
AN158_RS12400	COG1652	LysM domain
AN158_RS12405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AN158_RS12405	COG0352	thiamine-phosphate diphosphorylase activity
AN158_RS12405	COG0351	phosphomethylpyrimidine kinase
AN158_RS12415	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AN158_RS12445	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AN158_RS12475	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AN158_RS12490	COG0358	DNA primase activity
AN158_RS12500	COG0564	pseudouridine synthase activity
AN158_RS12525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AN158_RS12545	COG0583	DNA-binding transcription factor activity
AN158_RS12550	COG0473	3-isopropylmalate dehydrogenase activity
AN158_RS12560	COG0657	acetylesterase activity
AN158_RS12570	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS12590	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AN158_RS12590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN158_RS12605	COG1981	membrane
AN158_RS12650	COG0456	acetyltransferase
AN158_RS12660	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AN158_RS12665	COG0492	ferredoxin-NADP+ reductase activity
AN158_RS12670	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AN158_RS12670	COG1674	ftsk spoiiie
AN158_RS12675	COG1280	lysine exporter protein (LysE YggA)
AN158_RS12695	COG2894	cell division
AN158_RS12710	COG0204	Acyl-transferase
AN158_RS12715	COG2885	chlorophyll binding
AN158_RS12720	COG0210	DNA helicase
AN158_RS12730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN158_RS12745	COG0121	glutamine amidotransferase
AN158_RS12765	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN158_RS12770	COG0735	belongs to the Fur family
AN158_RS12795	COG0420	3'-5' exonuclease activity
AN158_RS12815	COG1090	epimerase
AN158_RS12830	COG2050	protein possibly involved in aromatic compounds catabolism
AN158_RS12840	COG2814	Major facilitator Superfamily
AN158_RS12845	COG0405	Gamma-glutamyltransferase
AN158_RS12900	COG0477	Major facilitator Superfamily
AN158_RS12905	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN158_RS12930	COG0531	amino acid
AN158_RS12935	COG2040	homocysteine
AN158_RS12960	COG1309	transcriptional regulator
AN158_RS12965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN158_RS12970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN158_RS12980	COG1607	acyl-coa hydrolase
AN158_RS12990	COG0523	cobalamin synthesis protein
AN158_RS13000	COG4681	YaeQ
AN158_RS13010	COG0726	polysaccharide deacetylase
AN158_RS13010	COG1649	PFAM Uncharacterised BCR, COG1649
AN158_RS13015	COG1215	transferase activity, transferring glycosyl groups
AN158_RS13025	COG1024	Enoyl-CoA hydratase
AN158_RS13040	COG1414	Transcriptional regulator
AN158_RS13060	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS13075	COG2271	Major facilitator Superfamily
AN158_RS13085	COG2267	carboxylic ester hydrolase activity
AN158_RS13090	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS13105	COG0028	Belongs to the TPP enzyme family
AN158_RS13115	COG0477	Major facilitator Superfamily
AN158_RS13120	COG0242	peptide deformylase activity
AN158_RS13125	COG2066	Belongs to the glutaminase family
AN158_RS13130	COG2207	Transcriptional regulator
AN158_RS13135	COG2223	nitrite transmembrane transporter activity
AN158_RS13150	COG0583	DNA-binding transcription factor activity
AN158_RS13155	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS13160	COG2271	Major facilitator Superfamily
AN158_RS13165	COG3959	Transketolase, thiamine diphosphate binding domain
AN158_RS13170	COG3958	Transketolase
AN158_RS13180	COG0306	phosphate transporter
AN158_RS13200	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AN158_RS13245	COG4181	ATPase activity
AN158_RS13250	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AN158_RS13275	COG0583	DNA-binding transcription factor activity
AN158_RS13285	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN158_RS13290	COG1773	rubredoxin
AN158_RS13335	COG2851	Citrate transporter
AN158_RS13340	COG1253	flavin adenine dinucleotide binding
AN158_RS13385	COG0804	urea catabolic process
AN158_RS13395	COG0830	nickel cation binding
AN158_RS13410	COG0742	ribosomal rna small subunit methyltransferase
AN158_RS13415	COG0768	penicillin binding
AN158_RS13435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AN158_RS13440	COG2878	Part of a membrane complex involved in electron transport
AN158_RS13445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN158_RS13455	COG3384	dioxygenase
AN158_RS13470	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AN158_RS13630	COG5410	chromosome segregation
AN158_RS13755	COG0739	heme binding
AN158_RS13850	COG0006	proline dipeptidase activity
AN158_RS13855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN158_RS13860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN158_RS13880	COG1279	arginine transmembrane transporter activity
AN158_RS13885	COG0583	DNA-binding transcription factor activity
AN158_RS13925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN158_RS13930	COG0741	lytic transglycosylase activity
AN158_RS13930	COG1388	LysM domain
AN158_RS13930	COG1388	LysM domain
AN158_RS13930	COG0741	lytic transglycosylase activity
AN158_RS13935	COG4166	transmembrane transport
AN158_RS13940	COG4174	ABC transporter (Permease)
AN158_RS13945	COG4239	(ABC) transporter, permease
AN158_RS13950	COG4172	Belongs to the ABC transporter superfamily
AN158_RS13970	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN158_RS13980	COG3706	GGDEF domain
AN158_RS13980	COG4251	negative regulation of phosphorylation
AN158_RS13980	COG2203	Gaf domain
AN158_RS13980	COG5001	Diguanylate cyclase
AN158_RS13990	COG1902	pentaerythritol trinitrate reductase activity
AN158_RS13990	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN158_RS14005	COG4269	membrane
AN158_RS14030	COG3209	COG3209 Rhs family protein
AN158_RS14070	COG1113	amino acid transport
AN158_RS14080	COG0531	amino acid
AN158_RS14100	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS14120	COG1113	amino acid transport
AN158_RS14135	COG0697	spore germination
AN158_RS14140	COG2721	sulfolactate sulfo-lyase activity
AN158_RS14145	COG2271	Major facilitator Superfamily
AN158_RS14150	COG4948	Mandelate Racemase Muconate Lactonizing
AN158_RS14160	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS14165	COG2186	Transcriptional regulator
AN158_RS14190	COG1960	acyl-CoA dehydrogenase activity
AN158_RS14200	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS14205	COG1024	Enoyl-CoA hydratase
AN158_RS14210	COG2814	Major facilitator Superfamily
AN158_RS14225	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN158_RS14270	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AN158_RS14275	COG2072	flavoprotein involved in K transport
AN158_RS14280	COG0300	oxidoreductase activity
AN158_RS14290	COG1309	transcriptional regulator
AN158_RS14295	COG1741	Belongs to the pirin family
AN158_RS14310	COG2072	flavoprotein involved in K transport
AN158_RS14320	COG2252	PERMEase
AN158_RS14325	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AN158_RS14330	COG3038	cytochrome b561
AN158_RS14340	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AN158_RS14350	COG0527	aspartate kinase activity
AN158_RS14360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN158_RS14375	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AN158_RS14390	COG0667	Aldo Keto reductase
AN158_RS14400	COG1765	OsmC-like protein
AN158_RS14415	COG0542	response to heat
AN158_RS14450	COG2885	chlorophyll binding
AN158_RS14460	COG0625	glutathione transferase activity
AN158_RS14465	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AN158_RS14485	COG3634	alkyl hydroperoxide reductase activity
AN158_RS14495	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AN158_RS14505	COG0450	alkyl hydroperoxide reductase
AN158_RS14510	COG1643	Atp-dependent helicase
AN158_RS14525	COG2814	Major facilitator Superfamily
AN158_RS14530	COG3135	benzoate transporter
AN158_RS14535	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS14540	COG0543	2 iron, 2 sulfur cluster binding
AN158_RS14540	COG0633	Ferredoxin
AN158_RS14545	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AN158_RS14550	COG4638	Rieske (2fe-2S)
AN158_RS14555	COG0583	DNA-binding transcription factor activity
AN158_RS14605	COG1570	exodeoxyribonuclease VII activity
AN158_RS14635	COG1280	lysine exporter protein (LysE YggA)
AN158_RS14640	COG1278	Cold shock
AN158_RS14670	COG2814	Major facilitator Superfamily
AN158_RS14735	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AN158_RS14745	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AN158_RS14750	COG1137	ATPase activity
AN158_RS14755	COG1538	Outer membrane efflux protein
AN158_RS14785	COG4122	O-methyltransferase activity
AN158_RS14795	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AN158_RS14810	COG1522	sequence-specific DNA binding
AN158_RS14825	COG1560	Kdo2-lipid A biosynthetic process
AN158_RS14830	COG0598	Magnesium transport protein CorA
AN158_RS14850	COG2814	Major facilitator Superfamily
AN158_RS14875	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN158_RS14910	COG3209	COG3209 Rhs family protein
AN158_RS14940	COG0583	DNA-binding transcription factor activity
AN158_RS14945	COG1914	H( )-stimulated, divalent metal cation uptake system
AN158_RS14965	COG4770	biotin carboxylase activity
AN158_RS14970	COG0038	chloride channel
AN158_RS14990	COG1063	alcohol dehydrogenase
AN158_RS15005	COG0439	Biotin carboxylase
AN158_RS15010	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN158_RS15015	COG1733	regulation of RNA biosynthetic process
AN158_RS15030	COG0864	Transcriptional regulator
AN158_RS15040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN158_RS15045	COG1116	anion transmembrane transporter activity
AN158_RS15160	COG0590	tRNA wobble adenosine to inosine editing
AN158_RS15165	COG2807	transmembrane transport
AN158_RS15180	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AN158_RS15190	COG0789	Transcriptional regulator
AN158_RS15200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN158_RS15220	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN158_RS15245	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS15250	COG0531	amino acid
AN158_RS15255	COG1760	l-serine dehydratase
AN158_RS15260	COG2030	dehydratase
AN158_RS15260	COG1012	belongs to the aldehyde dehydrogenase family
AN158_RS15265	COG3396	Phenylacetate-CoA oxygenase
AN158_RS15270	COG3460	Phenylacetate-CoA oxygenase
AN158_RS15275	COG3396	Phenylacetate-CoA oxygenase
AN158_RS15280	COG2151	metal-sulfur cluster biosynthetic enzyme
AN158_RS15285	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN158_RS15290	COG1024	Enoyl-CoA hydratase
AN158_RS15295	COG1024	Enoyl-CoA hydratase
AN158_RS15300	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN158_RS15305	COG0183	Belongs to the thiolase family
AN158_RS15310	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AN158_RS15315	COG3327	negative regulation of DNA-templated transcription, initiation
AN158_RS15325	COG2050	protein possibly involved in aromatic compounds catabolism
AN158_RS15350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AN158_RS15355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN158_RS15360	COG2271	Major facilitator Superfamily
AN158_RS15365	COG0753	catalase activity
AN158_RS15370	COG3038	cytochrome b561
AN158_RS15375	COG0583	DNA-binding transcription factor activity
AN158_RS15385	COG1414	Transcriptional regulator
AN158_RS15390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN158_RS15400	COG1840	ABC-type Fe3 transport system, periplasmic component
AN158_RS15405	COG3842	ATPase activity
AN158_RS15420	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AN158_RS15425	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN158_RS15430	COG2814	Major facilitator Superfamily
AN158_RS15435	COG1960	acyl-CoA dehydrogenase activity
AN158_RS15440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AN158_RS15450	COG1024	Enoyl-CoA hydratase
AN158_RS15460	COG2814	Major facilitator Superfamily
AN158_RS15470	COG0183	Belongs to the thiolase family
AN158_RS15475	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN158_RS15480	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS15485	COG1024	Enoyl-CoA hydratase
AN158_RS15490	COG1960	acyl-CoA dehydrogenase activity
AN158_RS15495	COG2814	Major facilitator Superfamily
AN158_RS15500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN158_RS15505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN158_RS15515	COG2814	Major facilitator Superfamily
AN158_RS15525	COG1960	acyl-CoA dehydrogenase activity
AN158_RS15540	COG0583	DNA-binding transcription factor activity
AN158_RS15550	COG4770	biotin carboxylase activity
AN158_RS15555	COG1024	Enoyl-CoA hydratase
AN158_RS15560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AN158_RS15565	COG1960	acyl-CoA dehydrogenase activity
AN158_RS15570	COG1309	transcriptional regulator
AN158_RS15575	COG0318	PFAM AMP-dependent synthetase and ligase
AN158_RS15595	COG0583	DNA-binding transcription factor activity
AN158_RS15645	COG1028	Short-chain dehydrogenase reductase Sdr
AN158_RS15665	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AN158_RS15685	COG2205	protein histidine kinase activity
AN158_RS15685	COG0784	Response regulator, receiver
AN158_RS15700	COG0765	amino acid transport
AN158_RS15705	COG0765	amino acid transport
AN158_RS15710	COG1126	abc transporter atp-binding protein
AN158_RS15715	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN158_RS15720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN158_RS15730	COG1280	lysine exporter protein (LysE YggA)
AN158_RS15735	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN158_RS15740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN158_RS15745	COG1045	serine acetyltransferase
AN158_RS15760	COG0583	DNA-binding transcription factor activity
AN158_RS15765	COG0625	glutathione transferase activity
AN158_RS15770	COG0625	glutathione transferase activity
AN158_RS15775	COG0583	DNA-binding transcription factor activity
AN158_RS15785	COG1346	cytolysis
AN158_RS15805	COG2814	Major facilitator Superfamily
AN158_RS15815	COG0583	DNA-binding transcription factor activity
AN158_RS15825	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AN158_RS15830	COG3052	prosthetic group binding
AN158_RS15850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AN158_RS15870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN158_RS15880	COG1294	oxidase, subunit
AN158_RS15885	COG1271	oxidase subunit
AN158_RS15905	COG0477	Major facilitator Superfamily
AN158_RS15915	COG4521	taurine ABC transporter
AN158_RS15920	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AN158_RS15925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN158_RS15930	COG2175	clavaminate synthase activity
AN158_RS15940	COG1953	Uracil, thiamine, allantoin
AN158_RS15950	COG0583	DNA-binding transcription factor activity
AN158_RS15960	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AN158_RS15975	COG0640	Transcriptional regulator
AN158_RS15980	COG0798	PFAM Bile acid sodium symporter
AN158_RS15985	COG0583	DNA-binding transcription factor activity
AN158_RS16000	COG3634	alkyl hydroperoxide reductase activity
AN158_RS16040	COG0436	Aminotransferase
AN158_RS16050	COG0386	Belongs to the glutathione peroxidase family
AN158_RS16090	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AN158_RS16115	COG0012	GTP binding
AN158_RS16120	COG2011	ABC-type metal ion transport system permease component
AN158_RS16125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AN158_RS16135	COG1464	Belongs to the NlpA lipoprotein family
AN158_RS16165	COG0765	amino acid transport
AN158_RS16170	COG0765	amino acid transport
AN158_RS16175	COG1126	abc transporter atp-binding protein
AN158_RS16185	COG1522	sequence-specific DNA binding
AN158_RS16200	COG1309	transcriptional regulator
AN158_RS16220	COG0583	DNA-binding transcription factor activity
AN158_RS16230	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AN158_RS16240	COG0697	spore germination
AN158_RS16265	COG3121	Chaperone
AN158_RS16270	COG3539	Fimbrial protein
AN158_RS16295	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AN158_RS16295	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AN158_RS16340	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AN158_RS16350	COG2353	YceI-like domain
AN158_RS16360	COG3698	Phosphodiester glycosidase
AN158_RS16375	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AN158_RS16380	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AN158_RS16380	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AN158_RS16380	COG0506	proline dehydrogenase activity
AN158_RS16390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN158_RS16395	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AN158_RS16415	COG1132	(ABC) transporter
AN158_RS16420	COG3122	Protein conserved in bacteria
AN158_RS16425	COG3619	membrane
AN158_RS16435	COG0640	Transcriptional regulator
AN158_RS16445	COG2850	peptidyl-arginine hydroxylation
AN158_RS16450	COG0424	maF-like protein
AN158_RS16470	COG0191	fructose-bisphosphate aldolase activity
AN158_RS16475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN158_RS16490	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AN158_RS16500	COG1192	Involved in chromosome partitioning
AN158_RS16505	COG1475	DNA binding
AN158_RS16510	COG0811	peptide transport
AN158_RS16520	COG1132	(ABC) transporter
AN158_RS16525	COG1663	tetraacyldisaccharide 4'-kinase activity
AN158_RS16545	COG0084	hydrolase, TatD family'
AN158_RS16610	COG0776	regulation of translation
AN158_RS16640	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AN158_RS16645	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AN158_RS16685	COG0339	signal peptide processing
AN158_RS16695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN158_RS16730	COG0702	epimerase
AN158_RS16735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AN158_RS16755	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AN158_RS16785	COG0316	Belongs to the HesB IscA family
AN158_RS16790	COG0822	iron-sulfur transferase activity
AN158_RS16815	COG0776	regulation of translation
AN158_RS16820	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN158_RS16825	COG2207	Transcriptional regulator
AN158_RS16830	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN158_RS16835	COG1960	acyl-CoA dehydrogenase activity
AN158_RS16840	COG1960	acyl-CoA dehydrogenase activity
AN158_RS16855	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AN158_RS16870	COG2814	Major facilitator Superfamily
AN158_RS16875	COG4264	IucA IucC family
AN158_RS16880	COG4264	IucA IucC family
AN158_RS16890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AN158_RS16920	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN158_RS16935	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AN158_RS16955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN158_RS16960	COG0730	response to heat
AN158_RS16980	COG4773	Receptor
AN158_RS16985	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN158_RS17000	COG1131	(ABC) transporter
AN158_RS17005	COG0842	Transport permease protein
AN158_RS17010	COG0842	Transport permease protein
AN158_RS17070	COG2226	methyltransferase
AN158_RS17095	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AN158_RS17130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN158_RS17140	COG0133	tryptophan synthase activity
AN158_RS17155	COG3706	GGDEF domain
AN158_RS17170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AN158_RS17175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AN158_RS17180	COG0022	dehydrogenase e1 component
AN158_RS17185	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN158_RS17190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN158_RS17200	COG1063	alcohol dehydrogenase
AN158_RS17205	COG3781	membrane
AN158_RS17225	COG0730	response to heat
AN158_RS17240	COG2207	Transcriptional regulator
AN158_RS17240	COG3708	Transcriptional regulator
AN158_RS17250	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AN158_RS17260	COG2188	Transcriptional regulator
AN158_RS17275	COG4521	taurine ABC transporter
AN158_RS17280	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN158_RS17300	COG0477	Major facilitator Superfamily
AN158_RS17310	COG1027	Aspartate ammonia-lyase
AN158_RS17325	COG0583	DNA-binding transcription factor activity
AN158_RS17675	COG1733	regulation of RNA biosynthetic process