locus-tag	class	description
FQZ18_RS00010	COG0592	DNA-directed DNA polymerase activity
FQZ18_RS00020	COG0187	DNA topoisomerase II activity
FQZ18_RS00030	COG0586	Pfam SNARE associated Golgi protein
FQZ18_RS00035	COG0488	(ABC) transporter
FQZ18_RS00060	COG0596	Alpha beta hydrolase
FQZ18_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FQZ18_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FQZ18_RS00110	COG0733	neurotransmitter:sodium symporter activity
FQZ18_RS00150	COG2233	PERMEase
FQZ18_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQZ18_RS00200	COG2814	Major facilitator Superfamily
FQZ18_RS00205	COG0656	L-ascorbic acid biosynthetic process
FQZ18_RS00210	COG0583	DNA-binding transcription factor activity
FQZ18_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQZ18_RS00230	COG1064	alcohol dehydrogenase
FQZ18_RS00235	COG2818	Glycosylase
FQZ18_RS00250	COG1194	a g-specific adenine glycosylase
FQZ18_RS00270	COG2983	Belongs to the UPF0260 family
FQZ18_RS00275	COG2133	pyrroloquinoline quinone binding
FQZ18_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FQZ18_RS00285	COG2116	formate transmembrane transporter activity
FQZ18_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FQZ18_RS00310	COG1335	isochorismatase
FQZ18_RS00315	COG0385	Bile acid
FQZ18_RS00320	COG0534	Mate efflux family protein
FQZ18_RS00325	COG1683	Conserved Protein
FQZ18_RS00345	COG0625	glutathione transferase activity
FQZ18_RS00355	COG1113	amino acid transport
FQZ18_RS00365	COG0523	cobalamin synthesis protein
FQZ18_RS00375	COG2188	Transcriptional regulator
FQZ18_RS00405	COG0010	Belongs to the arginase family
FQZ18_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FQZ18_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FQZ18_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FQZ18_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FQZ18_RS00540	COG0534	Mate efflux family protein
FQZ18_RS00545	COG0436	Aminotransferase
FQZ18_RS00550	COG2733	membrane
FQZ18_RS00565	COG2918	glutathione biosynthetic process
FQZ18_RS00580	COG0791	NLP P60 protein
FQZ18_RS00580	COG1388	LysM domain
FQZ18_RS00595	COG3150	esterase
FQZ18_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FQZ18_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQZ18_RS00630	COG2233	PERMEase
FQZ18_RS00635	COG2351	hydroxyisourate hydrolase activity
FQZ18_RS00670	COG3706	GGDEF domain
FQZ18_RS00685	COG1393	Belongs to the ArsC family
FQZ18_RS00690	COG0708	Exodeoxyribonuclease III
FQZ18_RS00710	COG0189	ligase activity
FQZ18_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FQZ18_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FQZ18_RS00755	COG4942	peptidase
FQZ18_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
FQZ18_RS00775	COG2119	membrane
FQZ18_RS00780	COG4774	siderophore transport
FQZ18_RS00785	COG0426	domain, Protein
FQZ18_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FQZ18_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FQZ18_RS00830	COG1902	pentaerythritol trinitrate reductase activity
FQZ18_RS00835	COG1519	Transferase
FQZ18_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FQZ18_RS00845	COG0668	transmembrane transport
FQZ18_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQZ18_RS00860	COG1335	isochorismatase
FQZ18_RS00865	COG1522	sequence-specific DNA binding
FQZ18_RS00870	COG3328	transposase activity
FQZ18_RS00895	COG0784	Response regulator, receiver
FQZ18_RS00895	COG2198	Histidine kinase
FQZ18_RS00895	COG2205	protein histidine kinase activity
FQZ18_RS00900	COG3162	membrane
FQZ18_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FQZ18_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQZ18_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FQZ18_RS00940	COG1309	transcriptional regulator
FQZ18_RS00960	COG0351	phosphomethylpyrimidine kinase
FQZ18_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
FQZ18_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FQZ18_RS00970	COG2814	Major facilitator Superfamily
FQZ18_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FQZ18_RS00995	COG1113	amino acid transport
FQZ18_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FQZ18_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS01020	COG1335	isochorismatase
FQZ18_RS01050	COG2814	Major facilitator Superfamily
FQZ18_RS01055	COG0583	DNA-binding transcription factor activity
FQZ18_RS01075	COG0667	Aldo Keto reductase
FQZ18_RS01105	COG1733	regulation of RNA biosynthetic process
FQZ18_RS01110	COG2249	NAD(P)H dehydrogenase (quinone) activity
FQZ18_RS01175	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FQZ18_RS01190	COG2329	Antibiotic biosynthesis monooxygenase
FQZ18_RS01220	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FQZ18_RS01250	COG0427	acetyl-CoA hydrolase
FQZ18_RS01275	COG0659	secondary active sulfate transmembrane transporter activity
FQZ18_RS01280	COG4221	oxidoreductase activity
FQZ18_RS01285	COG2873	o-acetylhomoserine
FQZ18_RS01290	COG0488	(ABC) transporter
FQZ18_RS01375	COG0833	amino acid
FQZ18_RS01420	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FQZ18_RS01425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FQZ18_RS01440	COG2226	methyltransferase
FQZ18_RS01490	COG0067	glutamate synthase
FQZ18_RS01490	COG0069	glutamate synthase activity
FQZ18_RS01490	COG0070	glutamate synthase
FQZ18_RS01495	COG0493	'glutamate synthase
FQZ18_RS01505	COG1704	LemA family
FQZ18_RS01510	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FQZ18_RS01530	COG3307	-O-antigen
FQZ18_RS01550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FQZ18_RS01565	COG0194	GDP metabolic process
FQZ18_RS01615	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FQZ18_RS01635	COG5380	lipid catabolic process
FQZ18_RS01640	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FQZ18_RS01665	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FQZ18_RS01670	COG0277	FAD linked oxidase domain protein
FQZ18_RS01680	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FQZ18_RS01685	COG2249	NAD(P)H dehydrogenase (quinone) activity
FQZ18_RS01700	COG1289	transmembrane transporter activity
FQZ18_RS01710	COG0628	permease
FQZ18_RS01715	COG1192	Involved in chromosome partitioning
FQZ18_RS01745	COG0833	amino acid
FQZ18_RS01750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FQZ18_RS01755	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FQZ18_RS01765	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS01805	COG0583	DNA-binding transcription factor activity
FQZ18_RS01850	COG0517	IMP dehydrogenase activity
FQZ18_RS01855	COG1983	PspC domain protein
FQZ18_RS01865	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS01880	COG0408	coproporphyrinogen oxidase activity
FQZ18_RS01900	COG0513	Belongs to the DEAD box helicase family
FQZ18_RS01910	COG1127	ABC transporter
FQZ18_RS01915	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FQZ18_RS01925	COG2854	intermembrane phospholipid transfer
FQZ18_RS01935	COG0598	Magnesium transport protein CorA
FQZ18_RS01945	COG0494	nUDIX hydrolase
FQZ18_RS01950	COG1040	competence protein
FQZ18_RS01955	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FQZ18_RS01975	COG1946	Acyl-CoA thioesterase
FQZ18_RS01980	COG1301	dicarboxylic acid transport
FQZ18_RS01990	COG3173	Aminoglycoside phosphotransferase
FQZ18_RS01995	COG0488	(ABC) transporter
FQZ18_RS02045	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FQZ18_RS02135	COG1959	2 iron, 2 sulfur cluster binding
FQZ18_RS02140	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FQZ18_RS02140	COG1017	nitric oxide dioxygenase activity
FQZ18_RS02150	COG0433	COG0433 Predicted ATPase
FQZ18_RS02155	COG0626	cystathionine gamma-synthase activity
FQZ18_RS02310	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS02315	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FQZ18_RS02345	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FQZ18_RS02350	COG0339	signal peptide processing
FQZ18_RS02355	COG0557	exoribonuclease II activity
FQZ18_RS02400	COG0179	Fumarylacetoacetate (FAA) hydrolase
FQZ18_RS02405	COG2169	Transcriptional regulator
FQZ18_RS02410	COG0697	spore germination
FQZ18_RS02415	COG1295	ribonuclease BN
FQZ18_RS02450	COG1702	phosphate starvation-inducible protein PhoH
FQZ18_RS02460	COG0741	lytic transglycosylase activity
FQZ18_RS02460	COG0739	heme binding
FQZ18_RS02460	COG1196	nuclear chromosome segregation
FQZ18_RS02495	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FQZ18_RS02500	COG1183	phosphatidylcholine synthase activity
FQZ18_RS02545	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS02550	COG1309	transcriptional regulator
FQZ18_RS02565	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FQZ18_RS02570	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS02590	COG2969	positive regulation of protein catabolic process
FQZ18_RS02600	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FQZ18_RS02615	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FQZ18_RS02620	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FQZ18_RS02955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FQZ18_RS02965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FQZ18_RS02970	COG1408	metallophosphoesterase
FQZ18_RS02980	COG2199	diguanylate cyclase activity
FQZ18_RS03040	COG1607	acyl-coa hydrolase
FQZ18_RS03070	COG2350	Protein conserved in bacteria
FQZ18_RS03080	COG0613	PHP domain protein
FQZ18_RS03085	COG3781	membrane
FQZ18_RS03095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FQZ18_RS03100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FQZ18_RS03110	COG1862	Preprotein translocase
FQZ18_RS03155	COG2205	protein histidine kinase activity
FQZ18_RS03160	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FQZ18_RS03180	COG0726	polysaccharide deacetylase
FQZ18_RS03185	COG0463	Glycosyl transferase, family 2
FQZ18_RS03190	COG0438	transferase activity, transferring glycosyl groups
FQZ18_RS03255	COG0625	glutathione transferase activity
FQZ18_RS03260	COG0583	DNA-binding transcription factor activity
FQZ18_RS03265	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS03270	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS03280	COG2205	protein histidine kinase activity
FQZ18_RS03285	COG0745	RESPONSE REGULATOR receiver
FQZ18_RS03290	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FQZ18_RS03310	COG2096	Adenosyltransferase
FQZ18_RS03360	COG0285	dihydrofolate synthase activity
FQZ18_RS03380	COG0450	alkyl hydroperoxide reductase
FQZ18_RS03395	COG0477	Major facilitator Superfamily
FQZ18_RS03400	COG1272	protein, Hemolysin III
FQZ18_RS03430	COG0183	Belongs to the thiolase family
FQZ18_RS03435	COG2207	Transcriptional regulator
FQZ18_RS03455	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FQZ18_RS03480	COG0183	Belongs to the thiolase family
FQZ18_RS03490	COG2885	chlorophyll binding
FQZ18_RS03490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FQZ18_RS03500	COG1690	Belongs to the RtcB family
FQZ18_RS03505	COG0833	amino acid
FQZ18_RS03515	COG2233	PERMEase
FQZ18_RS03520	COG1217	gtp-binding protein TYPA
FQZ18_RS03545	COG2094	Belongs to the DNA glycosylase MPG family
FQZ18_RS03550	COG4772	TonB-dependent receptor
FQZ18_RS03555	COG1902	pentaerythritol trinitrate reductase activity
FQZ18_RS03560	COG0679	Auxin Efflux Carrier
FQZ18_RS03570	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FQZ18_RS03575	COG0354	folic acid binding
FQZ18_RS03585	COG3189	MarR family transcriptional regulator
FQZ18_RS03590	COG2824	Alkylphosphonate utilization operon protein PhnA
FQZ18_RS03595	COG3422	double-strand break repair
FQZ18_RS03640	COG0840	transmembrane signaling receptor activity
FQZ18_RS03660	COG5510	response to toxic substance
FQZ18_RS03670	COG2832	Protein of unknown function (DUF454)
FQZ18_RS03675	COG1376	ErfK ybiS ycfS ynhG family protein
FQZ18_RS03715	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FQZ18_RS03725	COG1289	transmembrane transporter activity
FQZ18_RS03730	COG2814	Major facilitator Superfamily
FQZ18_RS03750	COG1115	amino acid carrier protein
FQZ18_RS03755	COG1752	Esterase of the alpha-beta hydrolase superfamily
FQZ18_RS03760	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FQZ18_RS03765	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FQZ18_RS03795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FQZ18_RS03805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FQZ18_RS03810	COG1077	Cell shape determining protein MreB Mrl
FQZ18_RS03815	COG1792	Involved in formation and maintenance of cell shape
FQZ18_RS03820	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FQZ18_RS03825	COG0424	maF-like protein
FQZ18_RS03830	COG1530	ribonuclease E activity
FQZ18_RS03840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQZ18_RS03850	COG0560	Phosphoserine phosphatase
FQZ18_RS03860	COG2249	NAD(P)H dehydrogenase (quinone) activity
FQZ18_RS03885	COG2207	Transcriptional regulator
FQZ18_RS03905	COG1113	amino acid transport
FQZ18_RS03910	COG2828	Protein conserved in bacteria
FQZ18_RS03915	COG0142	geranyltranstransferase activity
FQZ18_RS03920	COG2315	Protein conserved in bacteria
FQZ18_RS03935	COG1752	Esterase of the alpha-beta hydrolase superfamily
FQZ18_RS03955	COG2194	sulfuric ester hydrolase activity
FQZ18_RS03960	COG0745	RESPONSE REGULATOR receiver
FQZ18_RS03965	COG0642	Histidine kinase
FQZ18_RS03975	COG0004	ammonium transporteR
FQZ18_RS03980	COG0583	DNA-binding transcription factor activity
FQZ18_RS04000	COG0525	valine-tRNA ligase activity
FQZ18_RS04010	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS04020	COG0393	Putative heavy-metal-binding
FQZ18_RS04025	COG0393	Putative heavy-metal-binding
FQZ18_RS04030	COG1538	Outer membrane efflux protein
FQZ18_RS04040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQZ18_RS04045	COG0671	phosphoesterase, PA-phosphatase related
FQZ18_RS04075	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FQZ18_RS04090	COG1648	precorrin-2 dehydrogenase activity
FQZ18_RS04090	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FQZ18_RS04095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FQZ18_RS04100	COG1733	regulation of RNA biosynthetic process
FQZ18_RS04110	COG0531	amino acid
FQZ18_RS04125	COG0321	lipoyl(octanoyl) transferase activity
FQZ18_RS04130	COG2921	Belongs to the UPF0250 family
FQZ18_RS04175	COG2009	succinate dehydrogenase
FQZ18_RS04180	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FQZ18_RS04185	COG1053	succinate dehydrogenase
FQZ18_RS04190	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FQZ18_RS04215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FQZ18_RS04235	COG2354	Protein conserved in bacteria
FQZ18_RS04240	COG2321	neutral zinc metallopeptidase
FQZ18_RS04280	COG2843	Capsule synthesis protein
FQZ18_RS04295	COG0589	response to stress
FQZ18_RS04315	COG0505	Belongs to the CarA family
FQZ18_RS04340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQZ18_RS04345	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FQZ18_RS04395	COG0477	Major facilitator Superfamily
FQZ18_RS04400	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FQZ18_RS04415	COG1597	lipid kinase activity
FQZ18_RS04420	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FQZ18_RS04445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQZ18_RS04450	COG0584	glycerophosphoryl diester phosphodiesterase
FQZ18_RS04470	COG0741	lytic transglycosylase activity
FQZ18_RS04490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FQZ18_RS04505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQZ18_RS04530	COG0778	Nitroreductase
FQZ18_RS04545	COG1929	Belongs to the glycerate kinase type-1 family
FQZ18_RS04550	COG0243	molybdopterin cofactor binding
FQZ18_RS04555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FQZ18_RS04560	COG3339	Conserved Protein
FQZ18_RS04570	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FQZ18_RS04585	COG1113	amino acid transport
FQZ18_RS04595	COG0019	diaminopimelate decarboxylase activity
FQZ18_RS04605	COG1280	lysine exporter protein (LysE YggA)
FQZ18_RS04610	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FQZ18_RS04640	COG0463	Glycosyl transferase, family 2
FQZ18_RS04660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQZ18_RS04695	COG4591	ABC-type transport system involved in lipoprotein release permease component
FQZ18_RS04700	COG1136	(ABC) transporter
FQZ18_RS04705	COG2333	competence protein COMEC
FQZ18_RS04705	COG0658	competence protein
FQZ18_RS04715	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FQZ18_RS04715	COG0616	signal peptide processing
FQZ18_RS04720	COG0596	Alpha beta hydrolase
FQZ18_RS04725	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FQZ18_RS04735	COG0628	permease
FQZ18_RS04755	COG2826	transposase and inactivated derivatives, IS30 family
FQZ18_RS04780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FQZ18_RS04800	COG0823	Involved in the tonB-independent uptake of proteins
FQZ18_RS04820	COG0824	Thioesterase
FQZ18_RS04825	COG1473	amidohydrolase
FQZ18_RS04845	COG0047	phosphoribosylformylglycinamidine synthase activity
FQZ18_RS04845	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FQZ18_RS04850	COG2814	Major facilitator Superfamily
FQZ18_RS04860	COG1024	Enoyl-CoA hydratase
FQZ18_RS04865	COG1056	cytidyltransferase-related domain
FQZ18_RS04865	COG1051	belongs to the nudix hydrolase family
FQZ18_RS04875	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FQZ18_RS04890	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FQZ18_RS04905	COG4625	pathogenesis
FQZ18_RS04910	COG0583	DNA-binding transcription factor activity
FQZ18_RS04915	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FQZ18_RS04920	COG4208	sulfate ABC transporter
FQZ18_RS04925	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FQZ18_RS04935	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FQZ18_RS04940	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FQZ18_RS04945	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FQZ18_RS04965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FQZ18_RS04980	COG0681	Belongs to the peptidase S26 family
FQZ18_RS04995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FQZ18_RS05005	COG1381	Involved in DNA repair and RecF pathway recombination
FQZ18_RS05010	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FQZ18_RS05020	COG2826	transposase and inactivated derivatives, IS30 family
FQZ18_RS05025	COG4221	oxidoreductase activity
FQZ18_RS05055	COG0436	Aminotransferase
FQZ18_RS05075	COG0556	nucleotide-excision repair
FQZ18_RS05270	COG5410	chromosome segregation
FQZ18_RS05460	COG2070	2-Nitropropane dioxygenase
FQZ18_RS05490	COG1215	transferase activity, transferring glycosyl groups
FQZ18_RS05505	COG0415	Belongs to the DNA photolyase family
FQZ18_RS05515	COG1252	NADH dehydrogenase
FQZ18_RS05520	COG1686	Belongs to the peptidase S11 family
FQZ18_RS05535	COG1187	pseudouridine synthase activity
FQZ18_RS05560	COG0477	Major facilitator Superfamily
FQZ18_RS05565	COG0583	DNA-binding transcription factor activity
FQZ18_RS05570	COG1823	symporter activity
FQZ18_RS05580	COG0612	Peptidase, M16
FQZ18_RS05605	COG0352	thiamine-phosphate diphosphorylase activity
FQZ18_RS05640	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FQZ18_RS05655	COG1309	transcriptional regulator
FQZ18_RS05665	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FQZ18_RS05670	COG0076	glutamate decarboxylase activity
FQZ18_RS05680	COG1522	sequence-specific DNA binding
FQZ18_RS05685	COG3961	Belongs to the TPP enzyme family
FQZ18_RS05690	COG1113	amino acid transport
FQZ18_RS05695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FQZ18_RS05700	COG0573	inorganic phosphate transmembrane transporter activity
FQZ18_RS05710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FQZ18_RS05750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FQZ18_RS05755	COG1686	Belongs to the peptidase S11 family
FQZ18_RS05780	COG0583	DNA-binding transcription factor activity
FQZ18_RS05785	COG1067	ATP-dependent peptidase activity
FQZ18_RS05830	COG1966	Carbon starvation protein
FQZ18_RS05835	COG2879	small protein
FQZ18_RS05865	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FQZ18_RS05865	COG2508	Transcriptional regulator
FQZ18_RS05885	COG1113	amino acid transport
FQZ18_RS05890	COG0583	DNA-binding transcription factor activity
FQZ18_RS05895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQZ18_RS05900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQZ18_RS05910	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS05915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FQZ18_RS05920	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FQZ18_RS05920	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FQZ18_RS05955	COG2814	Major facilitator Superfamily
FQZ18_RS05960	COG4948	Mandelate Racemase Muconate Lactonizing
FQZ18_RS05970	COG1309	transcriptional regulator
FQZ18_RS05990	COG1741	Belongs to the pirin family
FQZ18_RS06000	COG2964	Protein conserved in bacteria
FQZ18_RS06015	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQZ18_RS06020	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQZ18_RS06025	COG4605	iron ion homeostasis
FQZ18_RS06030	COG4604	ABC transporter, ATP-binding protein
FQZ18_RS06035	COG4607	ABC-type enterochelin transport system periplasmic component
FQZ18_RS06040	COG4774	siderophore transport
FQZ18_RS06050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FQZ18_RS06055	COG1021	2,3-dihydroxybenzoate-AMP ligase
FQZ18_RS06060	COG3433	isochorismatase activity
FQZ18_RS06060	COG1535	isochorismatase
FQZ18_RS06075	COG1132	(ABC) transporter
FQZ18_RS06080	COG1132	(ABC) transporter
FQZ18_RS06085	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FQZ18_RS06095	COG1169	isochorismate synthase
FQZ18_RS06110	COG3739	integral membrane protein
FQZ18_RS06135	COG0302	gtp cyclohydrolase
FQZ18_RS06145	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FQZ18_RS06200	COG0512	Glutamine amidotransferase of anthranilate synthase
FQZ18_RS06215	COG0174	glutamine synthetase
FQZ18_RS06225	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FQZ18_RS06260	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FQZ18_RS06265	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FQZ18_RS06270	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FQZ18_RS06290	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FQZ18_RS06295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FQZ18_RS06300	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FQZ18_RS06315	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS06320	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FQZ18_RS06325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FQZ18_RS06335	COG2223	nitrite transmembrane transporter activity
FQZ18_RS06345	COG0024	Methionine aminopeptidase
FQZ18_RS06350	COG0052	Belongs to the universal ribosomal protein uS2 family
FQZ18_RS06365	COG2207	Transcriptional regulator
FQZ18_RS06390	COG2951	lytic endotransglycosylase activity
FQZ18_RS06395	COG0772	Belongs to the SEDS family
FQZ18_RS06410	COG0842	Transport permease protein
FQZ18_RS06415	COG1131	(ABC) transporter
FQZ18_RS06460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQZ18_RS06475	COG4215	(ABC) transporter
FQZ18_RS06480	COG4160	amino acid transport
FQZ18_RS06485	COG4598	ABC transporter
FQZ18_RS06495	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FQZ18_RS06500	COG0826	peptidase U32
FQZ18_RS06505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQZ18_RS06520	COG1720	tRNA m6t6A37 methyltransferase activity
FQZ18_RS06530	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FQZ18_RS06545	COG0642	Histidine kinase
FQZ18_RS06555	COG0494	nUDIX hydrolase
FQZ18_RS06565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FQZ18_RS06570	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FQZ18_RS06575	COG3139	Protein of unknown function (DUF1315)
FQZ18_RS06580	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FQZ18_RS06585	COG1301	dicarboxylic acid transport
FQZ18_RS06590	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS06595	COG2819	hydrolase of the alpha beta superfamily
FQZ18_RS06605	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FQZ18_RS06615	COG2195	Cleaves the N-terminal amino acid of tripeptides
FQZ18_RS06620	COG1234	tRNA 3'-trailer cleavage
FQZ18_RS06650	COG2363	Small membrane protein
FQZ18_RS06670	COG0513	Belongs to the DEAD box helicase family
FQZ18_RS06680	COG0778	Nitroreductase
FQZ18_RS06710	COG1286	toxin biosynthetic process
FQZ18_RS06735	COG4783	chaperone-mediated protein folding
FQZ18_RS06740	COG1610	YqeY-like protein
FQZ18_RS06840	COG3111	PFAM Bacterial OB fold (BOF) protein
FQZ18_RS06870	COG3243	poly(R)-hydroxyalkanoic acid synthase
FQZ18_RS06875	COG0786	glutamate:sodium symporter activity
FQZ18_RS06885	COG2186	Transcriptional regulator
FQZ18_RS06935	COG0477	Major facilitator Superfamily
FQZ18_RS06960	COG2985	domain, Protein
FQZ18_RS06970	COG2995	paraquat-inducible protein a
FQZ18_RS06975	COG3008	intermembrane lipid transfer
FQZ18_RS06975	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FQZ18_RS06985	COG1794	racemase activity, acting on amino acids and derivatives
FQZ18_RS07015	COG1301	dicarboxylic acid transport
FQZ18_RS07025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQZ18_RS07030	COG2011	ABC-type metal ion transport system permease component
FQZ18_RS07035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FQZ18_RS07040	COG1464	Belongs to the NlpA lipoprotein family
FQZ18_RS07045	COG0151	Belongs to the GarS family
FQZ18_RS07050	COG0138	bifunctional purine biosynthesis protein purh
FQZ18_RS07055	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FQZ18_RS07085	COG2308	Evidence 4 Homologs of previously reported genes of
FQZ18_RS07095	COG1305	Transglutaminase-like
FQZ18_RS07105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FQZ18_RS07110	COG0305	Participates in initiation and elongation during chromosome replication
FQZ18_RS07135	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FQZ18_RS07145	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FQZ18_RS07150	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FQZ18_RS07175	COG0726	polysaccharide deacetylase
FQZ18_RS07175	COG1649	PFAM Uncharacterised BCR, COG1649
FQZ18_RS07180	COG1215	transferase activity, transferring glycosyl groups
FQZ18_RS07185	COG3658	cytochrome
FQZ18_RS07195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQZ18_RS07210	COG0583	DNA-binding transcription factor activity
FQZ18_RS07230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FQZ18_RS07235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FQZ18_RS07250	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS07255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQZ18_RS07260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FQZ18_RS07285	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FQZ18_RS07290	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FQZ18_RS07300	COG2205	protein histidine kinase activity
FQZ18_RS07305	COG0745	RESPONSE REGULATOR receiver
FQZ18_RS07310	COG0174	glutamine synthetase
FQZ18_RS07330	COG0729	surface antigen
FQZ18_RS07355	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQZ18_RS07360	COG2814	Major facilitator Superfamily
FQZ18_RS07375	COG0583	DNA-binding transcription factor activity
FQZ18_RS07390	COG1187	pseudouridine synthase activity
FQZ18_RS07410	COG0802	atpase or kinase
FQZ18_RS07415	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FQZ18_RS07425	COG1923	regulation of RNA biosynthetic process
FQZ18_RS07430	COG0697	spore germination
FQZ18_RS07445	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FQZ18_RS07455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FQZ18_RS07460	COG0519	Catalyzes the synthesis of GMP from XMP
FQZ18_RS07460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FQZ18_RS07465	COG4302	ethanolamine ammonia-lyase activity
FQZ18_RS07470	COG4303	Ethanolamine ammonia lyase large subunit
FQZ18_RS07475	COG0531	amino acid
FQZ18_RS07495	COG1454	alcohol dehydrogenase
FQZ18_RS07500	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FQZ18_RS07510	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FQZ18_RS07530	COG0308	aminopeptidase N
FQZ18_RS07540	COG4221	oxidoreductase activity
FQZ18_RS07550	COG1605	Chorismate mutase
FQZ18_RS07565	COG1309	transcriptional regulator
FQZ18_RS07575	COG0668	transmembrane transport
FQZ18_RS07605	COG4773	Receptor
FQZ18_RS07625	COG0488	(ABC) transporter
FQZ18_RS07630	COG0589	response to stress
FQZ18_RS07655	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FQZ18_RS07665	COG3135	benzoate transporter
FQZ18_RS07670	COG1522	sequence-specific DNA binding
FQZ18_RS07680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FQZ18_RS07685	COG0583	DNA-binding transcription factor activity
FQZ18_RS07695	COG0183	Belongs to the thiolase family
FQZ18_RS07705	COG2030	dehydratase
FQZ18_RS07710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FQZ18_RS07725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FQZ18_RS07735	COG0824	Thioesterase
FQZ18_RS07740	COG1454	alcohol dehydrogenase
FQZ18_RS07750	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FQZ18_RS07770	COG0069	glutamate synthase activity
FQZ18_RS07905	COG1484	DNA-dependent DNA replication
FQZ18_RS08100	COG2026	Addiction module toxin, RelE StbE family
FQZ18_RS08140	COG0592	DNA-directed DNA polymerase activity
FQZ18_RS08170	COG2826	transposase and inactivated derivatives, IS30 family
FQZ18_RS08220	COG2814	Major facilitator Superfamily
FQZ18_RS08235	COG0511	ligase activity, forming carbon-carbon bonds
FQZ18_RS08255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FQZ18_RS08255	COG1116	anion transmembrane transporter activity
FQZ18_RS08260	COG0745	RESPONSE REGULATOR receiver
FQZ18_RS08270	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FQZ18_RS08270	COG2146	nitrite reductase [NAD(P)H] activity
FQZ18_RS08275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FQZ18_RS08280	COG0243	molybdopterin cofactor binding
FQZ18_RS08290	COG0243	molybdopterin cofactor binding
FQZ18_RS08295	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FQZ18_RS08310	COG0521	Mo-molybdopterin cofactor biosynthetic process
FQZ18_RS08310	COG0315	cyclic pyranopterin monophosphate synthase activity
FQZ18_RS08315	COG0303	'Molybdopterin
FQZ18_RS08325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQZ18_RS08330	COG0697	spore germination
FQZ18_RS08350	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FQZ18_RS08355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FQZ18_RS08410	COG2204	response regulator
FQZ18_RS08415	COG3852	Histidine kinase
FQZ18_RS08435	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FQZ18_RS08440	COG0575	Belongs to the CDS family
FQZ18_RS08475	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FQZ18_RS08490	COG2137	regulation of response to DNA damage stimulus
FQZ18_RS08500	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FQZ18_RS08505	COG1011	Hydrolase
FQZ18_RS08530	COG1522	sequence-specific DNA binding
FQZ18_RS08540	COG1113	amino acid transport
FQZ18_RS08555	COG0659	secondary active sulfate transmembrane transporter activity
FQZ18_RS08560	COG2135	peptidase activity
FQZ18_RS08575	COG5001	Diguanylate cyclase
FQZ18_RS08575	COG3300	MHYT domain
FQZ18_RS08595	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FQZ18_RS08595	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FQZ18_RS08595	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FQZ18_RS08600	COG1105	Belongs to the carbohydrate kinase PfkB family
FQZ18_RS08605	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FQZ18_RS08605	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FQZ18_RS08635	COG0024	Methionine aminopeptidase
FQZ18_RS08640	COG0583	DNA-binding transcription factor activity
FQZ18_RS08650	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FQZ18_RS08655	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FQZ18_RS08660	COG0517	IMP dehydrogenase activity
FQZ18_RS08660	COG0516	GMP reductase activity
FQZ18_RS08685	COG0552	protein localization to endoplasmic reticulum
FQZ18_RS08695	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FQZ18_RS08710	COG4890	Cyd operon protein YbgT
FQZ18_RS08715	COG1294	oxidase, subunit
FQZ18_RS08735	COG1585	Membrane protein implicated in regulation of membrane protease activity
FQZ18_RS08745	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FQZ18_RS08750	COG4774	siderophore transport
FQZ18_RS08765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FQZ18_RS08770	COG0569	domain protein
FQZ18_RS08775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FQZ18_RS08805	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FQZ18_RS08810	COG0542	response to heat
FQZ18_RS08835	COG0446	pyridine nucleotide-disulphide oxidoreductase
FQZ18_RS08835	COG1902	pentaerythritol trinitrate reductase activity
FQZ18_RS08880	COG2323	membrane
FQZ18_RS08885	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FQZ18_RS08895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FQZ18_RS08900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FQZ18_RS08905	COG0183	Belongs to the thiolase family
FQZ18_RS08910	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FQZ18_RS08915	COG0596	Alpha beta hydrolase
FQZ18_RS08920	COG2271	Major facilitator Superfamily
FQZ18_RS08925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FQZ18_RS08930	COG3485	protocatechuate 3,4-dioxygenase
FQZ18_RS08935	COG3485	protocatechuate 3,4-dioxygenase
FQZ18_RS08940	COG0710	3-dehydroquinate dehydratase activity
FQZ18_RS08945	COG3420	alginic acid biosynthetic process
FQZ18_RS08950	COG3659	wide pore channel activity
FQZ18_RS08955	COG4993	Dehydrogenase
FQZ18_RS08965	COG2391	methyltransferase activity
FQZ18_RS08980	COG1414	Transcriptional regulator
FQZ18_RS08985	COG0583	DNA-binding transcription factor activity
FQZ18_RS08990	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS09015	COG2814	Major facilitator Superfamily
FQZ18_RS09025	COG0154	amidase activity
FQZ18_RS09045	COG4638	Rieske (2fe-2S)
FQZ18_RS09055	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS09065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FQZ18_RS09075	COG3733	amine oxidase
FQZ18_RS09085	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS09095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FQZ18_RS09100	COG0183	Belongs to the thiolase family
FQZ18_RS09105	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FQZ18_RS09110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FQZ18_RS09120	COG4829	muconolactone delta-isomerase
FQZ18_RS09125	COG4948	Mandelate Racemase Muconate Lactonizing
FQZ18_RS09130	COG0583	DNA-binding transcription factor activity
FQZ18_RS09140	COG2186	Transcriptional regulator
FQZ18_RS09160	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS09180	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS09190	COG3829	transcription factor binding
FQZ18_RS09200	COG3162	membrane
FQZ18_RS09215	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS09230	COG0753	catalase activity
FQZ18_RS09250	COG1846	Transcriptional regulator
FQZ18_RS09255	COG1902	pentaerythritol trinitrate reductase activity
FQZ18_RS09255	COG0446	pyridine nucleotide-disulphide oxidoreductase
FQZ18_RS09265	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FQZ18_RS09295	COG1309	transcriptional regulator
FQZ18_RS09305	COG1335	isochorismatase
FQZ18_RS09310	COG0583	DNA-binding transcription factor activity
FQZ18_RS09320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FQZ18_RS09320	COG0475	glutathione-regulated potassium exporter activity
FQZ18_RS09330	COG1473	amidohydrolase
FQZ18_RS09340	COG2831	hemolysin activation secretion protein
FQZ18_RS09345	COG3210	domain, Protein
FQZ18_RS09375	COG2188	Transcriptional regulator
FQZ18_RS09390	COG0583	DNA-binding transcription factor activity
FQZ18_RS09420	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FQZ18_RS09440	COG1566	PFAM secretion protein HlyD family protein
FQZ18_RS09455	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS09460	COG0129	dihydroxy-acid dehydratase activity
FQZ18_RS09470	COG0583	DNA-binding transcription factor activity
FQZ18_RS09475	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FQZ18_RS09485	COG2084	Dehydrogenase
FQZ18_RS09490	COG2207	Transcriptional regulator
FQZ18_RS09505	COG1064	alcohol dehydrogenase
FQZ18_RS09515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FQZ18_RS09520	COG1120	ATPase activity
FQZ18_RS09545	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FQZ18_RS09660	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FQZ18_RS09710	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS09725	COG2207	Transcriptional regulator
FQZ18_RS09735	COG2205	protein histidine kinase activity
FQZ18_RS09740	COG0745	RESPONSE REGULATOR receiver
FQZ18_RS09745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQZ18_RS09750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQZ18_RS09755	COG1538	Outer membrane efflux protein
FQZ18_RS09765	COG2072	flavoprotein involved in K transport
FQZ18_RS09785	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FQZ18_RS09805	COG3539	Fimbrial protein
FQZ18_RS09835	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FQZ18_RS09845	COG0753	catalase activity
FQZ18_RS09860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FQZ18_RS09920	COG1535	isochorismatase
FQZ18_RS09920	COG3433	isochorismatase activity
FQZ18_RS09925	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS09930	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FQZ18_RS09935	COG4149	molybdate abc transporter
FQZ18_RS09940	COG0725	ABC transporter, periplasmic molybdate-binding protein
FQZ18_RS09950	COG4638	Rieske (2fe-2S)
FQZ18_RS09955	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FQZ18_RS09960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FQZ18_RS09960	COG0543	2 iron, 2 sulfur cluster binding
FQZ18_RS09985	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS10000	COG2207	Transcriptional regulator
FQZ18_RS10010	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS10015	COG2610	gluconate transmembrane transporter activity
FQZ18_RS10025	COG0583	DNA-binding transcription factor activity
FQZ18_RS10035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FQZ18_RS10040	COG2031	fatty acid transporter
FQZ18_RS10045	COG0183	Belongs to the thiolase family
FQZ18_RS10050	COG0583	DNA-binding transcription factor activity
FQZ18_RS10055	COG0583	DNA-binding transcription factor activity
FQZ18_RS10070	COG1027	Aspartate ammonia-lyase
FQZ18_RS10080	COG0477	Major facilitator Superfamily
FQZ18_RS10100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FQZ18_RS10105	COG4521	taurine ABC transporter
FQZ18_RS10120	COG2188	Transcriptional regulator
FQZ18_RS10130	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FQZ18_RS10135	COG1733	regulation of RNA biosynthetic process
FQZ18_RS10140	COG3708	Transcriptional regulator
FQZ18_RS10140	COG2207	Transcriptional regulator
FQZ18_RS10155	COG0730	response to heat
FQZ18_RS10165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQZ18_RS10165	COG3453	Protein conserved in bacteria
FQZ18_RS10175	COG3781	membrane
FQZ18_RS10180	COG1063	alcohol dehydrogenase
FQZ18_RS10190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FQZ18_RS10195	COG0508	dehydrogenase complex catalyzes the overall conversion of
FQZ18_RS10200	COG0022	dehydrogenase e1 component
FQZ18_RS10205	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FQZ18_RS10210	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FQZ18_RS10230	COG3706	GGDEF domain
FQZ18_RS10245	COG0133	tryptophan synthase activity
FQZ18_RS10255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FQZ18_RS10290	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FQZ18_RS10315	COG2226	methyltransferase
FQZ18_RS10370	COG0842	Transport permease protein
FQZ18_RS10375	COG0842	Transport permease protein
FQZ18_RS10380	COG1131	(ABC) transporter
FQZ18_RS10395	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FQZ18_RS10400	COG4773	Receptor
FQZ18_RS10420	COG0730	response to heat
FQZ18_RS10425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FQZ18_RS10445	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FQZ18_RS10460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FQZ18_RS10500	COG4264	IucA IucC family
FQZ18_RS10505	COG4264	IucA IucC family
FQZ18_RS10525	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FQZ18_RS10540	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS10545	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS10550	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FQZ18_RS10555	COG2207	Transcriptional regulator
FQZ18_RS10560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FQZ18_RS10565	COG0776	regulation of translation
FQZ18_RS10590	COG0822	iron-sulfur transferase activity
FQZ18_RS10595	COG0316	Belongs to the HesB IscA family
FQZ18_RS10625	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FQZ18_RS10645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FQZ18_RS10650	COG0702	epimerase
FQZ18_RS10690	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FQZ18_RS10700	COG0339	signal peptide processing
FQZ18_RS10750	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FQZ18_RS10755	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FQZ18_RS10785	COG0776	regulation of translation
FQZ18_RS10850	COG0084	hydrolase, TatD family'
FQZ18_RS10870	COG1663	tetraacyldisaccharide 4'-kinase activity
FQZ18_RS10875	COG1132	(ABC) transporter
FQZ18_RS10885	COG0811	peptide transport
FQZ18_RS10890	COG1475	DNA binding
FQZ18_RS10895	COG1192	Involved in chromosome partitioning
FQZ18_RS10905	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FQZ18_RS10920	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FQZ18_RS10925	COG0191	fructose-bisphosphate aldolase activity
FQZ18_RS10945	COG0424	maF-like protein
FQZ18_RS10950	COG2850	peptidyl-arginine hydroxylation
FQZ18_RS10960	COG0640	Transcriptional regulator
FQZ18_RS10970	COG3619	membrane
FQZ18_RS10980	COG2826	transposase and inactivated derivatives, IS30 family
FQZ18_RS10990	COG1132	(ABC) transporter
FQZ18_RS11010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FQZ18_RS11015	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FQZ18_RS11025	COG0506	proline dehydrogenase activity
FQZ18_RS11025	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FQZ18_RS11025	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FQZ18_RS11030	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FQZ18_RS11045	COG3698	Phosphodiester glycosidase
FQZ18_RS11055	COG2353	YceI-like domain
FQZ18_RS11065	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FQZ18_RS11110	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FQZ18_RS11110	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FQZ18_RS11135	COG3539	Fimbrial protein
FQZ18_RS11140	COG3121	Chaperone
FQZ18_RS11165	COG0697	spore germination
FQZ18_RS11175	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FQZ18_RS11185	COG0583	DNA-binding transcription factor activity
FQZ18_RS11205	COG1309	transcriptional regulator
FQZ18_RS11220	COG1522	sequence-specific DNA binding
FQZ18_RS11230	COG1126	abc transporter atp-binding protein
FQZ18_RS11235	COG0765	amino acid transport
FQZ18_RS11240	COG0765	amino acid transport
FQZ18_RS11270	COG1464	Belongs to the NlpA lipoprotein family
FQZ18_RS11280	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FQZ18_RS11285	COG2011	ABC-type metal ion transport system permease component
FQZ18_RS11290	COG0012	GTP binding
FQZ18_RS11315	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FQZ18_RS11355	COG0386	Belongs to the glutathione peroxidase family
FQZ18_RS11365	COG0436	Aminotransferase
FQZ18_RS11405	COG3634	alkyl hydroperoxide reductase activity
FQZ18_RS11420	COG0583	DNA-binding transcription factor activity
FQZ18_RS11425	COG0798	PFAM Bile acid sodium symporter
FQZ18_RS11430	COG0640	Transcriptional regulator
FQZ18_RS11445	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FQZ18_RS11455	COG0583	DNA-binding transcription factor activity
FQZ18_RS11465	COG1953	Uracil, thiamine, allantoin
FQZ18_RS11475	COG2175	clavaminate synthase activity
FQZ18_RS11480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FQZ18_RS11485	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FQZ18_RS11490	COG4521	taurine ABC transporter
FQZ18_RS11500	COG0477	Major facilitator Superfamily
FQZ18_RS11520	COG1271	oxidase subunit
FQZ18_RS11525	COG1294	oxidase, subunit
FQZ18_RS11535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQZ18_RS11555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FQZ18_RS11575	COG3052	prosthetic group binding
FQZ18_RS11580	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FQZ18_RS11590	COG2814	Major facilitator Superfamily
FQZ18_RS11610	COG1346	cytolysis
FQZ18_RS11620	COG0583	DNA-binding transcription factor activity
FQZ18_RS11625	COG0625	glutathione transferase activity
FQZ18_RS11630	COG0625	glutathione transferase activity
FQZ18_RS11635	COG0583	DNA-binding transcription factor activity
FQZ18_RS11650	COG1045	serine acetyltransferase
FQZ18_RS11655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FQZ18_RS11660	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FQZ18_RS11670	COG1280	lysine exporter protein (LysE YggA)
FQZ18_RS11685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQZ18_RS11690	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQZ18_RS11695	COG1126	abc transporter atp-binding protein
FQZ18_RS11700	COG0765	amino acid transport
FQZ18_RS11705	COG0765	amino acid transport
FQZ18_RS11725	COG2205	protein histidine kinase activity
FQZ18_RS11725	COG0784	Response regulator, receiver
FQZ18_RS11745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FQZ18_RS11765	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS11815	COG0583	DNA-binding transcription factor activity
FQZ18_RS11835	COG0318	PFAM AMP-dependent synthetase and ligase
FQZ18_RS11840	COG1309	transcriptional regulator
FQZ18_RS11845	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS11850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FQZ18_RS11855	COG1024	Enoyl-CoA hydratase
FQZ18_RS11860	COG4770	biotin carboxylase activity
FQZ18_RS11870	COG0583	DNA-binding transcription factor activity
FQZ18_RS11885	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS11895	COG2814	Major facilitator Superfamily
FQZ18_RS11905	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FQZ18_RS11910	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FQZ18_RS11915	COG2814	Major facilitator Superfamily
FQZ18_RS11920	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS11925	COG1024	Enoyl-CoA hydratase
FQZ18_RS11930	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS11935	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQZ18_RS11940	COG0183	Belongs to the thiolase family
FQZ18_RS11950	COG2814	Major facilitator Superfamily
FQZ18_RS11960	COG1024	Enoyl-CoA hydratase
FQZ18_RS11975	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS11980	COG2814	Major facilitator Superfamily
FQZ18_RS11985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FQZ18_RS11990	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FQZ18_RS12005	COG3842	ATPase activity
FQZ18_RS12010	COG1840	ABC-type Fe3 transport system, periplasmic component
FQZ18_RS12020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQZ18_RS12025	COG1414	Transcriptional regulator
FQZ18_RS12035	COG0583	DNA-binding transcription factor activity
FQZ18_RS12040	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FQZ18_RS12045	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS12055	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FQZ18_RS12065	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS12070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQZ18_RS12075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FQZ18_RS12080	COG2267	carboxylic ester hydrolase activity
FQZ18_RS12100	COG3038	cytochrome b561
FQZ18_RS12105	COG0753	catalase activity
FQZ18_RS12135	COG2050	protein possibly involved in aromatic compounds catabolism
FQZ18_RS12145	COG3327	negative regulation of DNA-templated transcription, initiation
FQZ18_RS12150	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FQZ18_RS12155	COG0183	Belongs to the thiolase family
FQZ18_RS12160	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQZ18_RS12165	COG1024	Enoyl-CoA hydratase
FQZ18_RS12170	COG1024	Enoyl-CoA hydratase
FQZ18_RS12175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FQZ18_RS12180	COG2151	metal-sulfur cluster biosynthetic enzyme
FQZ18_RS12185	COG3396	Phenylacetate-CoA oxygenase
FQZ18_RS12190	COG3460	Phenylacetate-CoA oxygenase
FQZ18_RS12195	COG3396	Phenylacetate-CoA oxygenase
FQZ18_RS12200	COG2030	dehydratase
FQZ18_RS12200	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS12205	COG1760	l-serine dehydratase
FQZ18_RS12210	COG0531	amino acid
FQZ18_RS12215	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS12230	COG0446	pyridine nucleotide-disulphide oxidoreductase
FQZ18_RS12240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FQZ18_RS12260	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FQZ18_RS12270	COG0789	Transcriptional regulator
FQZ18_RS12285	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FQZ18_RS12300	COG2807	transmembrane transport
FQZ18_RS12305	COG0590	tRNA wobble adenosine to inosine editing
FQZ18_RS12420	COG1116	anion transmembrane transporter activity
FQZ18_RS12425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FQZ18_RS12435	COG0864	Transcriptional regulator
FQZ18_RS12455	COG2249	NAD(P)H dehydrogenase (quinone) activity
FQZ18_RS12460	COG0439	Biotin carboxylase
FQZ18_RS12475	COG1063	alcohol dehydrogenase
FQZ18_RS12485	COG1309	transcriptional regulator
FQZ18_RS12505	COG0038	chloride channel
FQZ18_RS12510	COG4770	biotin carboxylase activity
FQZ18_RS12530	COG1914	H( )-stimulated, divalent metal cation uptake system
FQZ18_RS12535	COG0583	DNA-binding transcription factor activity
FQZ18_RS12585	COG1250	3-hydroxyacyl-CoA dehydrogenase
FQZ18_RS12605	COG2814	Major facilitator Superfamily
FQZ18_RS12615	COG1560	Kdo2-lipid A biosynthetic process
FQZ18_RS12625	COG5006	permease, DMT superfamily
FQZ18_RS12630	COG1522	sequence-specific DNA binding
FQZ18_RS12645	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FQZ18_RS12655	COG4122	O-methyltransferase activity
FQZ18_RS12685	COG1538	Outer membrane efflux protein
FQZ18_RS12690	COG1137	ATPase activity
FQZ18_RS12695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FQZ18_RS12705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FQZ18_RS12710	COG0517	IMP dehydrogenase activity
FQZ18_RS12710	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FQZ18_RS12960	COG2814	Major facilitator Superfamily
FQZ18_RS12995	COG1278	Cold shock
FQZ18_RS13000	COG1280	lysine exporter protein (LysE YggA)
FQZ18_RS13030	COG1570	exodeoxyribonuclease VII activity
FQZ18_RS13080	COG0583	DNA-binding transcription factor activity
FQZ18_RS13085	COG4638	Rieske (2fe-2S)
FQZ18_RS13090	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FQZ18_RS13095	COG0633	Ferredoxin
FQZ18_RS13095	COG0543	2 iron, 2 sulfur cluster binding
FQZ18_RS13100	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS13105	COG3135	benzoate transporter
FQZ18_RS13110	COG2814	Major facilitator Superfamily
FQZ18_RS13125	COG1643	Atp-dependent helicase
FQZ18_RS13130	COG0450	alkyl hydroperoxide reductase
FQZ18_RS13140	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FQZ18_RS13150	COG3634	alkyl hydroperoxide reductase activity
FQZ18_RS13170	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FQZ18_RS13175	COG0625	glutathione transferase activity
FQZ18_RS13185	COG2885	chlorophyll binding
FQZ18_RS13220	COG0542	response to heat
FQZ18_RS13235	COG1765	OsmC-like protein
FQZ18_RS13255	COG0667	Aldo Keto reductase
FQZ18_RS13270	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FQZ18_RS13280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FQZ18_RS13290	COG0527	aspartate kinase activity
FQZ18_RS13300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FQZ18_RS13310	COG3038	cytochrome b561
FQZ18_RS13315	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FQZ18_RS13320	COG2252	PERMEase
FQZ18_RS13330	COG2072	flavoprotein involved in K transport
FQZ18_RS13345	COG1741	Belongs to the pirin family
FQZ18_RS13350	COG1309	transcriptional regulator
FQZ18_RS13360	COG0300	oxidoreductase activity
FQZ18_RS13525	COG4269	membrane
FQZ18_RS13540	COG0446	pyridine nucleotide-disulphide oxidoreductase
FQZ18_RS13540	COG1902	pentaerythritol trinitrate reductase activity
FQZ18_RS13550	COG2203	Gaf domain
FQZ18_RS13550	COG4251	negative regulation of phosphorylation
FQZ18_RS13550	COG3706	GGDEF domain
FQZ18_RS13550	COG5001	Diguanylate cyclase
FQZ18_RS13560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FQZ18_RS13580	COG4172	Belongs to the ABC transporter superfamily
FQZ18_RS13585	COG4239	(ABC) transporter, permease
FQZ18_RS13590	COG4174	ABC transporter (Permease)
FQZ18_RS13600	COG0741	lytic transglycosylase activity
FQZ18_RS13600	COG1388	LysM domain
FQZ18_RS13600	COG1388	LysM domain
FQZ18_RS13600	COG0741	lytic transglycosylase activity
FQZ18_RS13605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FQZ18_RS13645	COG0583	DNA-binding transcription factor activity
FQZ18_RS13650	COG1279	arginine transmembrane transporter activity
FQZ18_RS13670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQZ18_RS13675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQZ18_RS13680	COG0006	proline dipeptidase activity
FQZ18_RS13720	COG2194	sulfuric ester hydrolase activity
FQZ18_RS13765	COG0739	heme binding
FQZ18_RS14090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FQZ18_RS14120	COG3384	dioxygenase
FQZ18_RS14130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FQZ18_RS14135	COG2878	Part of a membrane complex involved in electron transport
FQZ18_RS14140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FQZ18_RS14165	COG0768	penicillin binding
FQZ18_RS14170	COG0742	ribosomal rna small subunit methyltransferase
FQZ18_RS14185	COG0830	nickel cation binding
FQZ18_RS14195	COG0804	urea catabolic process
FQZ18_RS14235	COG1253	flavin adenine dinucleotide binding
FQZ18_RS14240	COG2851	Citrate transporter
FQZ18_RS14290	COG1773	rubredoxin
FQZ18_RS14295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FQZ18_RS14305	COG0583	DNA-binding transcription factor activity
FQZ18_RS14330	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FQZ18_RS14335	COG4181	ATPase activity
FQZ18_RS14380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FQZ18_RS14400	COG0306	phosphate transporter
FQZ18_RS14410	COG3958	Transketolase
FQZ18_RS14415	COG3959	Transketolase, thiamine diphosphate binding domain
FQZ18_RS14420	COG2271	Major facilitator Superfamily
FQZ18_RS14425	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS14430	COG0583	DNA-binding transcription factor activity
FQZ18_RS14445	COG2223	nitrite transmembrane transporter activity
FQZ18_RS14450	COG2207	Transcriptional regulator
FQZ18_RS14455	COG2066	Belongs to the glutaminase family
FQZ18_RS14460	COG0242	peptide deformylase activity
FQZ18_RS14465	COG0477	Major facilitator Superfamily
FQZ18_RS14475	COG0028	Belongs to the TPP enzyme family
FQZ18_RS14490	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS14495	COG2267	carboxylic ester hydrolase activity
FQZ18_RS14505	COG2271	Major facilitator Superfamily
FQZ18_RS14510	COG0446	pyridine nucleotide-disulphide oxidoreductase
FQZ18_RS14520	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS14540	COG1414	Transcriptional regulator
FQZ18_RS14555	COG1024	Enoyl-CoA hydratase
FQZ18_RS14565	COG1215	transferase activity, transferring glycosyl groups
FQZ18_RS14570	COG0726	polysaccharide deacetylase
FQZ18_RS14570	COG1649	PFAM Uncharacterised BCR, COG1649
FQZ18_RS14580	COG4681	YaeQ
FQZ18_RS14590	COG0523	cobalamin synthesis protein
FQZ18_RS14600	COG1607	acyl-coa hydrolase
FQZ18_RS14610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQZ18_RS14615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FQZ18_RS14620	COG1309	transcriptional regulator
FQZ18_RS14645	COG2040	homocysteine
FQZ18_RS14650	COG0531	amino acid
FQZ18_RS14675	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FQZ18_RS14680	COG0477	Major facilitator Superfamily
FQZ18_RS14720	COG0405	Gamma-glutamyltransferase
FQZ18_RS14725	COG2814	Major facilitator Superfamily
FQZ18_RS14735	COG2050	protein possibly involved in aromatic compounds catabolism
FQZ18_RS14750	COG1090	epimerase
FQZ18_RS14770	COG0420	3'-5' exonuclease activity
FQZ18_RS14795	COG0735	belongs to the Fur family
FQZ18_RS14800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FQZ18_RS14820	COG0121	glutamine amidotransferase
FQZ18_RS14835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQZ18_RS14845	COG0210	DNA helicase
FQZ18_RS14850	COG2885	chlorophyll binding
FQZ18_RS14855	COG0204	Acyl-transferase
FQZ18_RS14870	COG2894	cell division
FQZ18_RS14895	COG1280	lysine exporter protein (LysE YggA)
FQZ18_RS14900	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FQZ18_RS14900	COG1674	ftsk spoiiie
FQZ18_RS14905	COG0492	ferredoxin-NADP+ reductase activity
FQZ18_RS14910	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FQZ18_RS14920	COG0456	acetyltransferase
FQZ18_RS14965	COG1981	membrane
FQZ18_RS14980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FQZ18_RS14980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FQZ18_RS15000	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS15010	COG0657	acetylesterase activity
FQZ18_RS15020	COG0473	3-isopropylmalate dehydrogenase activity
FQZ18_RS15025	COG0583	DNA-binding transcription factor activity
FQZ18_RS15045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FQZ18_RS15070	COG0564	pseudouridine synthase activity
FQZ18_RS15080	COG0358	DNA primase activity
FQZ18_RS15095	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FQZ18_RS15125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FQZ18_RS15155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FQZ18_RS15165	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FQZ18_RS15165	COG0352	thiamine-phosphate diphosphorylase activity
FQZ18_RS15165	COG0351	phosphomethylpyrimidine kinase
FQZ18_RS15170	COG1652	LysM domain
FQZ18_RS15195	COG1399	metal-binding, possibly nucleic acid-binding protein
FQZ18_RS15200	COG3101	peptidyl-lysine hydroxylation
FQZ18_RS15205	COG0009	L-threonylcarbamoyladenylate synthase
FQZ18_RS15210	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FQZ18_RS15215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FQZ18_RS15230	COG4106	trans-aconitate 2-methyltransferase activity
FQZ18_RS15245	COG2226	methyltransferase
FQZ18_RS15245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FQZ18_RS15245	COG0596	Alpha beta hydrolase
FQZ18_RS15250	COG1877	trehalose-phosphatase activity
FQZ18_RS15255	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FQZ18_RS15260	COG2223	nitrite transmembrane transporter activity
FQZ18_RS15280	COG1196	nuclear chromosome segregation
FQZ18_RS15290	COG0730	response to heat
FQZ18_RS15305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FQZ18_RS15315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FQZ18_RS15365	COG0489	protein tyrosine kinase activity
FQZ18_RS15375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQZ18_RS15375	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQZ18_RS15405	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FQZ18_RS15410	COG2081	HI0933 family
FQZ18_RS15420	COG0668	transmembrane transport
FQZ18_RS15440	COG0583	DNA-binding transcription factor activity
FQZ18_RS15460	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FQZ18_RS15465	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FQZ18_RS15495	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FQZ18_RS15535	COG0745	RESPONSE REGULATOR receiver
FQZ18_RS15555	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FQZ18_RS15565	COG2205	protein histidine kinase activity
FQZ18_RS15635	COG4993	Dehydrogenase
FQZ18_RS15660	COG0384	phenazine biosynthesis protein PhzF
FQZ18_RS15680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FQZ18_RS15695	COG0583	DNA-binding transcription factor activity
FQZ18_RS15725	COG0583	DNA-binding transcription factor activity
FQZ18_RS15740	COG0583	DNA-binding transcription factor activity
FQZ18_RS15745	COG1053	succinate dehydrogenase
FQZ18_RS15755	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FQZ18_RS15760	COG2814	Major facilitator Superfamily
FQZ18_RS15765	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS15770	COG0583	DNA-binding transcription factor activity
FQZ18_RS15775	COG1063	alcohol dehydrogenase
FQZ18_RS15805	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FQZ18_RS15810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FQZ18_RS15815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FQZ18_RS15830	COG3667	copper resistance
FQZ18_RS15835	COG2132	Multicopper oxidase
FQZ18_RS15845	COG0561	phosphatase activity
FQZ18_RS15850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FQZ18_RS15875	COG1214	PFAM Peptidase M22, glycoprotease
FQZ18_RS15925	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FQZ18_RS15935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FQZ18_RS15940	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FQZ18_RS15945	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FQZ18_RS16005	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FQZ18_RS16015	COG1846	Transcriptional regulator
FQZ18_RS16020	COG1764	response to oxidative stress
FQZ18_RS16060	COG0037	tRNA processing
FQZ18_RS16070	COG0248	Ppx GppA phosphatase
FQZ18_RS16100	COG0072	phenylalanine-tRNA ligase activity
FQZ18_RS16140	COG1238	metal cluster binding
FQZ18_RS16145	COG0625	glutathione transferase activity
FQZ18_RS16160	COG0318	PFAM AMP-dependent synthetase and ligase
FQZ18_RS16165	COG3028	Belongs to the UPF0307 family
FQZ18_RS16170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FQZ18_RS16190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FQZ18_RS16195	COG0617	tRNA 3'-terminal CCA addition
FQZ18_RS16200	COG1555	photosystem II stabilization
FQZ18_RS16205	COG3956	TIGRFAM MazG family protein
FQZ18_RS16215	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FQZ18_RS16235	COG2205	protein histidine kinase activity
FQZ18_RS16235	COG0784	Response regulator, receiver
FQZ18_RS16235	COG5002	protein histidine kinase activity
FQZ18_RS16240	COG1024	Enoyl-CoA hydratase
FQZ18_RS16260	COG3622	Belongs to the hyi family
FQZ18_RS16290	COG0697	spore germination
FQZ18_RS16300	COG2814	Major facilitator Superfamily
FQZ18_RS16305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FQZ18_RS16315	COG0583	DNA-binding transcription factor activity
FQZ18_RS16325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FQZ18_RS16340	COG0084	hydrolase, TatD family'
FQZ18_RS16355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FQZ18_RS16385	COG0440	acetolactate synthase activity
FQZ18_RS16390	COG0028	Belongs to the TPP enzyme family
FQZ18_RS16415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FQZ18_RS16420	COG1136	(ABC) transporter
FQZ18_RS16420	COG0577	efflux transmembrane transporter activity
FQZ18_RS16425	COG1538	Outer membrane efflux protein
FQZ18_RS16440	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FQZ18_RS16445	COG1162	GTPase activity
FQZ18_RS16455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FQZ18_RS16475	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FQZ18_RS16480	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS16520	COG2986	histidine ammonia-lyase
FQZ18_RS16535	COG0318	PFAM AMP-dependent synthetase and ligase
FQZ18_RS16545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FQZ18_RS16590	COG1426	Protein conserved in bacteria
FQZ18_RS16625	COG0793	Belongs to the peptidase S41A family
FQZ18_RS16640	COG2267	carboxylic ester hydrolase activity
FQZ18_RS16650	COG1012	belongs to the aldehyde dehydrogenase family
FQZ18_RS16655	COG3265	gluconokinase activity
FQZ18_RS16665	COG0800	Aldolase
FQZ18_RS16675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FQZ18_RS16680	COG0280	phosphate acetyltransferase
FQZ18_RS16680	COG0857	belongs to the CobB CobQ family
FQZ18_RS16685	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FQZ18_RS16685	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FQZ18_RS16705	COG0740	serine-type endopeptidase activity
FQZ18_RS16715	COG4774	siderophore transport
FQZ18_RS16725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FQZ18_RS16735	COG2813	Specifically methylates the guanine in position
FQZ18_RS16735	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FQZ18_RS16835	COG0788	formyltetrahydrofolate deformylase activity
FQZ18_RS16860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FQZ18_RS16860	COG4651	solute:proton antiporter activity
FQZ18_RS16880	COG0724	RNA recognition motif
FQZ18_RS16885	COG0210	DNA helicase
FQZ18_RS16910	COG1733	regulation of RNA biosynthetic process
FQZ18_RS16920	COG2900	Belongs to the SlyX family
FQZ18_RS16925	COG0488	(ABC) transporter
FQZ18_RS16930	COG1280	lysine exporter protein (LysE YggA)
FQZ18_RS16935	COG1560	Kdo2-lipid A biosynthetic process
FQZ18_RS16945	COG1301	dicarboxylic acid transport
FQZ18_RS17000	COG0473	3-isopropylmalate dehydrogenase activity
FQZ18_RS17065	COG0583	DNA-binding transcription factor activity
FQZ18_RS17075	COG0625	glutathione transferase activity
FQZ18_RS17080	COG2378	regulation of single-species biofilm formation
FQZ18_RS17085	COG0546	phosphoglycolate phosphatase activity
FQZ18_RS17095	COG1530	ribonuclease E activity
FQZ18_RS17100	COG0318	PFAM AMP-dependent synthetase and ligase
FQZ18_RS17115	COG0583	DNA-binding transcription factor activity
FQZ18_RS17120	COG4221	oxidoreductase activity
FQZ18_RS17125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FQZ18_RS17135	COG0534	Mate efflux family protein
FQZ18_RS17150	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FQZ18_RS17190	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FQZ18_RS17195	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FQZ18_RS17210	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FQZ18_RS17220	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FQZ18_RS17220	COG0644	oxidoreductase
FQZ18_RS17225	COG0425	Belongs to the sulfur carrier protein TusA family
FQZ18_RS17230	COG4535	Mg2 and Co2 transporter CorC
FQZ18_RS17240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FQZ18_RS17260	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FQZ18_RS17265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FQZ18_RS17265	COG0475	glutathione-regulated potassium exporter activity
FQZ18_RS17270	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FQZ18_RS17280	COG0484	heat shock protein binding
FQZ18_RS17285	COG0789	Transcriptional regulator
FQZ18_RS17290	COG0598	Magnesium transport protein CorA
FQZ18_RS17305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FQZ18_RS17310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FQZ18_RS17315	COG1074	ATP-dependent DNA helicase activity
FQZ18_RS17320	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FQZ18_RS17340	COG2226	methyltransferase
FQZ18_RS17355	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FQZ18_RS17360	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FQZ18_RS17375	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FQZ18_RS17375	COG2111	Na H antiporter
FQZ18_RS17380	COG1006	Multisubunit Na H antiporter MnhC subunit
FQZ18_RS17385	COG0651	ATP synthesis coupled electron transport
FQZ18_RS17390	COG1863	multisubunit Na H antiporter MnhE subunit
FQZ18_RS17395	COG2212	antiporter activity
FQZ18_RS17400	COG1320	monovalent cation:proton antiporter activity
FQZ18_RS17415	COG0195	Participates in both transcription termination and antitermination
FQZ18_RS17465	COG0237	dephospho-CoA kinase activity
FQZ18_RS17475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FQZ18_RS17490	COG0497	DNA recombination
FQZ18_RS17500	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FQZ18_RS17530	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FQZ18_RS17530	COG2169	Transcriptional regulator
FQZ18_RS17535	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FQZ18_RS17600	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FQZ18_RS17615	COG0326	Molecular chaperone. Has ATPase activity
FQZ18_RS17630	COG2056	Na+-H+ antiporter family
FQZ18_RS17635	COG0596	Alpha beta hydrolase
FQZ18_RS17740	COG0546	phosphoglycolate phosphatase activity
FQZ18_RS17745	COG1716	ATPase activity
FQZ18_RS17790	COG0181	hydroxymethylbilane synthase activity
FQZ18_RS17800	COG3275	phosphorelay sensor kinase activity
FQZ18_RS17820	COG1538	Outer membrane efflux protein
FQZ18_RS17825	COG0697	spore germination
FQZ18_RS17850	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FQZ18_RS17855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FQZ18_RS17860	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FQZ18_RS17865	COG0772	Belongs to the SEDS family
FQZ18_RS17890	COG4974	Belongs to the 'phage' integrase family
FQZ18_RS17895	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FQZ18_RS17905	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FQZ18_RS17915	COG2197	response regulator
FQZ18_RS17930	COG0793	Belongs to the peptidase S41A family
FQZ18_RS17935	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FQZ18_RS17940	COG0795	lipopolysaccharide-transporting ATPase activity
FQZ18_RS17980	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FQZ18_RS17980	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FQZ18_RS17990	COG0004	ammonium transporteR
FQZ18_RS17995	COG0347	Belongs to the P(II) protein family
FQZ18_RS18005	COG0606	chelatase, subunit chli
FQZ18_RS18060	COG0659	secondary active sulfate transmembrane transporter activity
FQZ18_RS18065	COG0589	response to stress
FQZ18_RS18140	COG0606	chelatase, subunit chli
FQZ18_RS18145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FQZ18_RS18155	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FQZ18_RS18170	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FQZ18_RS18185	COG0318	PFAM AMP-dependent synthetase and ligase
FQZ18_RS18195	COG0477	Major facilitator Superfamily
FQZ18_RS18200	COG2860	membrane
FQZ18_RS18210	COG1253	flavin adenine dinucleotide binding
FQZ18_RS18230	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FQZ18_RS18265	COG0655	NAD(P)H dehydrogenase (quinone) activity
FQZ18_RS18275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FQZ18_RS18310	COG1309	transcriptional regulator
FQZ18_RS18345	COG0758	DNA mediated transformation
FQZ18_RS18355	COG0697	spore germination
FQZ18_RS18360	COG1309	transcriptional regulator
FQZ18_RS18375	COG0386	Belongs to the glutathione peroxidase family
FQZ18_RS18440	COG1121	(ABC) transporter
FQZ18_RS18445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FQZ18_RS18450	COG1280	lysine exporter protein (LysE YggA)
FQZ18_RS18455	COG2837	iron assimilation
FQZ18_RS18465	COG0281	malic enzyme
FQZ18_RS18510	COG0519	Catalyzes the synthesis of GMP from XMP
FQZ18_RS18510	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FQZ18_RS18515	COG4399	Belongs to the UPF0754 family
FQZ18_RS18520	COG2259	Doxx family
FQZ18_RS18525	COG0586	Pfam SNARE associated Golgi protein
FQZ18_RS18540	COG1192	Involved in chromosome partitioning
FQZ18_RS18550	COG0271	Belongs to the BolA IbaG family
FQZ18_RS18570	COG2267	carboxylic ester hydrolase activity
FQZ18_RS18590	COG3321	synthase
FQZ18_RS18590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FQZ18_RS18590	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FQZ18_RS18590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FQZ18_RS18595	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS18605	COG2197	response regulator
FQZ18_RS18615	COG3916	Acyl-homoserine-lactone synthase
FQZ18_RS18620	COG0477	Major facilitator Superfamily
FQZ18_RS18625	COG1024	Enoyl-CoA hydratase
FQZ18_RS18630	COG1024	Enoyl-CoA hydratase
FQZ18_RS18635	COG1960	acyl-CoA dehydrogenase activity
FQZ18_RS18640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FQZ18_RS18660	COG1113	amino acid transport
FQZ18_RS18665	COG1113	amino acid transport
FQZ18_RS18670	COG0251	oxidation-reduction process
FQZ18_RS18710	COG0564	pseudouridine synthase activity
FQZ18_RS18770	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FQZ18_RS18785	COG1802	Transcriptional regulator
FQZ18_RS18795	COG1448	Aminotransferase
FQZ18_RS18800	COG0277	FAD linked oxidase domain protein
FQZ18_RS18810	COG2186	Transcriptional regulator
FQZ18_RS18820	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FQZ18_RS18825	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FQZ18_RS18840	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FQZ18_RS18845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FQZ18_RS18850	COG1216	Glycosyl transferase, family 2
FQZ18_RS18880	COG2089	acid synthase
FQZ18_RS18895	COG1083	cytidylyl-transferase
FQZ18_RS18900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FQZ18_RS18905	COG1086	Polysaccharide biosynthesis protein
FQZ18_RS18910	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FQZ18_RS18915	COG1596	polysaccharide export
FQZ18_RS18940	COG0728	peptidoglycan biosynthetic process
FQZ18_RS18945	COG3023	N-Acetylmuramoyl-L-alanine amidase
FQZ18_RS19000	COG0546	phosphoglycolate phosphatase activity
FQZ18_RS19005	COG1028	Short-chain dehydrogenase reductase Sdr
FQZ18_RS19025	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FQZ18_RS19030	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FQZ18_RS19035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FQZ18_RS19040	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FQZ18_RS19045	COG1116	anion transmembrane transporter activity
FQZ18_RS19050	COG1309	transcriptional regulator
FQZ18_RS19055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FQZ18_RS19065	COG0196	riboflavin kinase activity
FQZ18_RS19070	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FQZ18_RS19080	COG1047	Peptidyl-prolyl cis-trans
FQZ18_RS19120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FQZ18_RS19125	COG0657	acetylesterase activity
FQZ18_RS19175	COG2951	lytic endotransglycosylase activity
FQZ18_RS19180	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FQZ18_RS19195	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FQZ18_RS19205	COG0671	phosphoesterase, PA-phosphatase related
FQZ18_RS19210	COG0861	Integral membrane protein TerC family
FQZ18_RS19220	COG0754	glutathionylspermidine amidase activity
FQZ18_RS19230	COG0402	S-adenosylhomocysteine deaminase activity
FQZ18_RS19245	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FQZ18_RS19250	COG1230	cation diffusion facilitator family transporter
FQZ18_RS19265	COG0706	membrane insertase activity
FQZ18_RS19315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde