locus-tag	class	description
AOT16_RS00010	COG0592	DNA-directed DNA polymerase activity
AOT16_RS00020	COG0187	DNA topoisomerase II activity
AOT16_RS00030	COG0586	Pfam SNARE associated Golgi protein
AOT16_RS00035	COG0488	(ABC) transporter
AOT16_RS00060	COG0596	Alpha beta hydrolase
AOT16_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AOT16_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AOT16_RS00130	COG0733	neurotransmitter:sodium symporter activity
AOT16_RS00170	COG2233	PERMEase
AOT16_RS00185	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_RS00220	COG2814	Major facilitator Superfamily
AOT16_RS00225	COG0656	L-ascorbic acid biosynthetic process
AOT16_RS00230	COG0583	DNA-binding transcription factor activity
AOT16_RS00240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_RS00245	COG1064	alcohol dehydrogenase
AOT16_RS00250	COG2818	Glycosylase
AOT16_RS00265	COG1194	a g-specific adenine glycosylase
AOT16_RS00285	COG2983	Belongs to the UPF0260 family
AOT16_RS00290	COG2133	pyrroloquinoline quinone binding
AOT16_RS00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOT16_RS00300	COG2116	formate transmembrane transporter activity
AOT16_RS00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT16_RS00325	COG1335	isochorismatase
AOT16_RS00330	COG0385	Bile acid
AOT16_RS00335	COG0534	Mate efflux family protein
AOT16_RS00340	COG1683	Conserved Protein
AOT16_RS00360	COG0625	glutathione transferase activity
AOT16_RS00370	COG1113	amino acid transport
AOT16_RS00380	COG0523	cobalamin synthesis protein
AOT16_RS00390	COG2188	Transcriptional regulator
AOT16_RS00420	COG0010	Belongs to the arginase family
AOT16_RS00435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOT16_RS00440	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AOT16_RS00450	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AOT16_RS00455	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AOT16_RS00560	COG0534	Mate efflux family protein
AOT16_RS00565	COG0436	Aminotransferase
AOT16_RS00570	COG2733	membrane
AOT16_RS00585	COG2918	glutathione biosynthetic process
AOT16_RS00600	COG1388	LysM domain
AOT16_RS00600	COG0791	NLP P60 protein
AOT16_RS00625	COG3150	esterase
AOT16_RS00635	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS00640	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AOT16_RS00650	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_RS00660	COG2233	PERMEase
AOT16_RS00665	COG2351	hydroxyisourate hydrolase activity
AOT16_RS00700	COG3706	GGDEF domain
AOT16_RS00715	COG1393	Belongs to the ArsC family
AOT16_RS00720	COG0708	Exodeoxyribonuclease III
AOT16_RS00740	COG0189	ligase activity
AOT16_RS00760	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AOT16_RS00770	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AOT16_RS00785	COG4942	peptidase
AOT16_RS00795	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOT16_RS00805	COG2119	membrane
AOT16_RS00810	COG4774	siderophore transport
AOT16_RS00830	COG4774	siderophore transport
AOT16_RS00835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_RS00835	COG0426	domain, Protein
AOT16_RS00860	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AOT16_RS00880	COG1902	pentaerythritol trinitrate reductase activity
AOT16_RS00885	COG1519	Transferase
AOT16_RS00890	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOT16_RS00895	COG0668	transmembrane transport
AOT16_RS00905	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOT16_RS00910	COG1335	isochorismatase
AOT16_RS00915	COG1522	sequence-specific DNA binding
AOT16_RS00920	COG3328	transposase activity
AOT16_RS00945	COG2205	protein histidine kinase activity
AOT16_RS00945	COG2198	Histidine kinase
AOT16_RS00945	COG0784	Response regulator, receiver
AOT16_RS00950	COG3162	membrane
AOT16_RS00955	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOT16_RS00965	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_RS00985	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AOT16_RS00990	COG1309	transcriptional regulator
AOT16_RS01010	COG0351	phosphomethylpyrimidine kinase
AOT16_RS01010	COG0352	thiamine-phosphate diphosphorylase activity
AOT16_RS01010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOT16_RS01020	COG2814	Major facilitator Superfamily
AOT16_RS01035	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AOT16_RS01045	COG1113	amino acid transport
AOT16_RS01055	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOT16_RS01060	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS01070	COG1335	isochorismatase
AOT16_RS01100	COG2814	Major facilitator Superfamily
AOT16_RS01105	COG0583	DNA-binding transcription factor activity
AOT16_RS01125	COG0667	Aldo Keto reductase
AOT16_RS01160	COG1733	regulation of RNA biosynthetic process
AOT16_RS01170	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT16_RS01235	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AOT16_RS01250	COG2329	Antibiotic biosynthesis monooxygenase
AOT16_RS01280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AOT16_RS01310	COG0427	acetyl-CoA hydrolase
AOT16_RS01330	COG0659	secondary active sulfate transmembrane transporter activity
AOT16_RS01335	COG4221	oxidoreductase activity
AOT16_RS01340	COG2873	o-acetylhomoserine
AOT16_RS01345	COG0488	(ABC) transporter
AOT16_RS01425	COG0833	amino acid
AOT16_RS01470	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AOT16_RS01475	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AOT16_RS01490	COG2226	methyltransferase
AOT16_RS01540	COG0067	glutamate synthase
AOT16_RS01540	COG0069	glutamate synthase activity
AOT16_RS01540	COG0070	glutamate synthase
AOT16_RS01545	COG0493	'glutamate synthase
AOT16_RS01555	COG1704	LemA family
AOT16_RS01560	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AOT16_RS01580	COG3307	-O-antigen
AOT16_RS01600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOT16_RS01610	COG0194	GDP metabolic process
AOT16_RS01660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AOT16_RS01680	COG5380	lipid catabolic process
AOT16_RS01685	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AOT16_RS01710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AOT16_RS01715	COG0277	FAD linked oxidase domain protein
AOT16_RS01725	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AOT16_RS01730	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT16_RS01745	COG1289	transmembrane transporter activity
AOT16_RS01755	COG0628	permease
AOT16_RS01760	COG1192	Involved in chromosome partitioning
AOT16_RS01790	COG0833	amino acid
AOT16_RS01795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOT16_RS01800	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOT16_RS01810	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS01850	COG0583	DNA-binding transcription factor activity
AOT16_RS01895	COG0517	IMP dehydrogenase activity
AOT16_RS01900	COG1983	PspC domain protein
AOT16_RS01910	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS01925	COG0408	coproporphyrinogen oxidase activity
AOT16_RS01945	COG0513	Belongs to the DEAD box helicase family
AOT16_RS01950	COG1127	ABC transporter
AOT16_RS01955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AOT16_RS01965	COG2854	intermembrane phospholipid transfer
AOT16_RS01975	COG0598	Magnesium transport protein CorA
AOT16_RS01985	COG0494	nUDIX hydrolase
AOT16_RS01990	COG1040	competence protein
AOT16_RS01995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AOT16_RS02015	COG1946	Acyl-CoA thioesterase
AOT16_RS02020	COG1301	dicarboxylic acid transport
AOT16_RS02035	COG1959	2 iron, 2 sulfur cluster binding
AOT16_RS02040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT16_RS02040	COG1017	nitric oxide dioxygenase activity
AOT16_RS02045	COG0433	COG0433 Predicted ATPase
AOT16_RS02050	COG0626	cystathionine gamma-synthase activity
AOT16_RS02205	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS02210	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AOT16_RS02240	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AOT16_RS02245	COG0339	signal peptide processing
AOT16_RS02250	COG0557	exoribonuclease II activity
AOT16_RS02295	COG0179	Fumarylacetoacetate (FAA) hydrolase
AOT16_RS02300	COG2169	Transcriptional regulator
AOT16_RS02305	COG0697	spore germination
AOT16_RS02310	COG1295	ribonuclease BN
AOT16_RS02345	COG1702	phosphate starvation-inducible protein PhoH
AOT16_RS02355	COG0739	heme binding
AOT16_RS02355	COG0741	lytic transglycosylase activity
AOT16_RS02355	COG1196	nuclear chromosome segregation
AOT16_RS02385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AOT16_RS02390	COG1183	phosphatidylcholine synthase activity
AOT16_RS02435	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS02440	COG1309	transcriptional regulator
AOT16_RS02455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOT16_RS02460	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS02480	COG2969	positive regulation of protein catabolic process
AOT16_RS02490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AOT16_RS02505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AOT16_RS02510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AOT16_RS02530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AOT16_RS02540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOT16_RS02545	COG1408	metallophosphoesterase
AOT16_RS02555	COG2199	diguanylate cyclase activity
AOT16_RS02615	COG1607	acyl-coa hydrolase
AOT16_RS02645	COG2350	Protein conserved in bacteria
AOT16_RS02655	COG0613	PHP domain protein
AOT16_RS02660	COG3781	membrane
AOT16_RS02670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AOT16_RS02675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AOT16_RS02685	COG1862	Preprotein translocase
AOT16_RS02730	COG2205	protein histidine kinase activity
AOT16_RS02735	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AOT16_RS02755	COG0726	polysaccharide deacetylase
AOT16_RS02760	COG0463	Glycosyl transferase, family 2
AOT16_RS02765	COG0438	transferase activity, transferring glycosyl groups
AOT16_RS02830	COG0625	glutathione transferase activity
AOT16_RS02835	COG0583	DNA-binding transcription factor activity
AOT16_RS02840	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS02845	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS02855	COG2205	protein histidine kinase activity
AOT16_RS02860	COG0745	RESPONSE REGULATOR receiver
AOT16_RS02865	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AOT16_RS02885	COG2096	Adenosyltransferase
AOT16_RS02935	COG0285	dihydrofolate synthase activity
AOT16_RS02955	COG0450	alkyl hydroperoxide reductase
AOT16_RS02970	COG0477	Major facilitator Superfamily
AOT16_RS02975	COG1272	protein, Hemolysin III
AOT16_RS03010	COG0183	Belongs to the thiolase family
AOT16_RS03015	COG2207	Transcriptional regulator
AOT16_RS03035	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_RS03055	COG0183	Belongs to the thiolase family
AOT16_RS03065	COG2885	chlorophyll binding
AOT16_RS03065	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AOT16_RS03075	COG1690	Belongs to the RtcB family
AOT16_RS03080	COG0833	amino acid
AOT16_RS03090	COG2233	PERMEase
AOT16_RS03095	COG1217	gtp-binding protein TYPA
AOT16_RS03120	COG2094	Belongs to the DNA glycosylase MPG family
AOT16_RS03125	COG4772	TonB-dependent receptor
AOT16_RS03145	COG4772	TonB-dependent receptor
AOT16_RS03150	COG1902	pentaerythritol trinitrate reductase activity
AOT16_RS03155	COG0679	Auxin Efflux Carrier
AOT16_RS03165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT16_RS03170	COG0354	folic acid binding
AOT16_RS03180	COG3189	MarR family transcriptional regulator
AOT16_RS03185	COG2824	Alkylphosphonate utilization operon protein PhnA
AOT16_RS03190	COG3422	double-strand break repair
AOT16_RS03230	COG0840	transmembrane signaling receptor activity
AOT16_RS03250	COG5510	response to toxic substance
AOT16_RS03260	COG2832	Protein of unknown function (DUF454)
AOT16_RS03265	COG1376	ErfK ybiS ycfS ynhG family protein
AOT16_RS03305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AOT16_RS03315	COG1289	transmembrane transporter activity
AOT16_RS03320	COG2814	Major facilitator Superfamily
AOT16_RS03335	COG1115	amino acid carrier protein
AOT16_RS03340	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOT16_RS03345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOT16_RS03350	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AOT16_RS03380	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOT16_RS03390	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AOT16_RS03395	COG1077	Cell shape determining protein MreB Mrl
AOT16_RS03400	COG1792	Involved in formation and maintenance of cell shape
AOT16_RS03405	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AOT16_RS03410	COG0424	maF-like protein
AOT16_RS03415	COG1530	ribonuclease E activity
AOT16_RS03420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT16_RS03430	COG0560	Phosphoserine phosphatase
AOT16_RS03440	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT16_RS03465	COG2207	Transcriptional regulator
AOT16_RS03485	COG1113	amino acid transport
AOT16_RS03490	COG2828	Protein conserved in bacteria
AOT16_RS03495	COG0142	geranyltranstransferase activity
AOT16_RS03500	COG2315	Protein conserved in bacteria
AOT16_RS03515	COG1752	Esterase of the alpha-beta hydrolase superfamily
AOT16_RS03535	COG2194	sulfuric ester hydrolase activity
AOT16_RS03540	COG0745	RESPONSE REGULATOR receiver
AOT16_RS03545	COG0642	Histidine kinase
AOT16_RS03555	COG0004	ammonium transporteR
AOT16_RS03565	COG0583	DNA-binding transcription factor activity
AOT16_RS03585	COG0525	valine-tRNA ligase activity
AOT16_RS03595	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS03605	COG0393	Putative heavy-metal-binding
AOT16_RS03610	COG0393	Putative heavy-metal-binding
AOT16_RS03615	COG1538	Outer membrane efflux protein
AOT16_RS03625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_RS03630	COG0671	phosphoesterase, PA-phosphatase related
AOT16_RS03660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AOT16_RS03675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AOT16_RS03675	COG1648	precorrin-2 dehydrogenase activity
AOT16_RS03680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AOT16_RS03685	COG1733	regulation of RNA biosynthetic process
AOT16_RS03695	COG0531	amino acid
AOT16_RS03710	COG0321	lipoyl(octanoyl) transferase activity
AOT16_RS03715	COG2921	Belongs to the UPF0250 family
AOT16_RS03755	COG2009	succinate dehydrogenase
AOT16_RS03760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AOT16_RS03765	COG1053	succinate dehydrogenase
AOT16_RS03770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AOT16_RS03790	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT16_RS03810	COG2354	Protein conserved in bacteria
AOT16_RS03815	COG2321	neutral zinc metallopeptidase
AOT16_RS03845	COG2843	Capsule synthesis protein
AOT16_RS03860	COG0589	response to stress
AOT16_RS03880	COG0505	Belongs to the CarA family
AOT16_RS03910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOT16_RS03915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AOT16_RS03965	COG0477	Major facilitator Superfamily
AOT16_RS03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AOT16_RS03985	COG1597	lipid kinase activity
AOT16_RS03990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOT16_RS04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT16_RS04020	COG0584	glycerophosphoryl diester phosphodiesterase
AOT16_RS04040	COG0741	lytic transglycosylase activity
AOT16_RS04065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AOT16_RS04080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT16_RS04110	COG0778	Nitroreductase
AOT16_RS04125	COG1929	Belongs to the glycerate kinase type-1 family
AOT16_RS04130	COG0243	molybdopterin cofactor binding
AOT16_RS04135	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AOT16_RS04150	COG3339	Conserved Protein
AOT16_RS04160	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AOT16_RS04175	COG1113	amino acid transport
AOT16_RS04185	COG0019	diaminopimelate decarboxylase activity
AOT16_RS04195	COG1280	lysine exporter protein (LysE YggA)
AOT16_RS04200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOT16_RS04230	COG0463	Glycosyl transferase, family 2
AOT16_RS04250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_RS04280	COG4591	ABC-type transport system involved in lipoprotein release permease component
AOT16_RS04285	COG1136	(ABC) transporter
AOT16_RS04290	COG0658	competence protein
AOT16_RS04290	COG2333	competence protein COMEC
AOT16_RS04300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AOT16_RS04300	COG0616	signal peptide processing
AOT16_RS04305	COG0596	Alpha beta hydrolase
AOT16_RS04310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AOT16_RS04320	COG0628	permease
AOT16_RS04355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOT16_RS04375	COG0823	Involved in the tonB-independent uptake of proteins
AOT16_RS04395	COG0824	Thioesterase
AOT16_RS04400	COG1473	amidohydrolase
AOT16_RS04420	COG0047	phosphoribosylformylglycinamidine synthase activity
AOT16_RS04420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AOT16_RS04425	COG2814	Major facilitator Superfamily
AOT16_RS04435	COG1024	Enoyl-CoA hydratase
AOT16_RS04440	COG1056	cytidyltransferase-related domain
AOT16_RS04440	COG1051	belongs to the nudix hydrolase family
AOT16_RS04450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AOT16_RS04465	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AOT16_RS04480	COG4625	pathogenesis
AOT16_RS04485	COG0583	DNA-binding transcription factor activity
AOT16_RS04490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AOT16_RS04495	COG4208	sulfate ABC transporter
AOT16_RS04500	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AOT16_RS04510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AOT16_RS04515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AOT16_RS04520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AOT16_RS04540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOT16_RS04555	COG0681	Belongs to the peptidase S26 family
AOT16_RS04570	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AOT16_RS04580	COG1381	Involved in DNA repair and RecF pathway recombination
AOT16_RS04585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AOT16_RS04595	COG4221	oxidoreductase activity
AOT16_RS04620	COG0436	Aminotransferase
AOT16_RS04640	COG0556	nucleotide-excision repair
AOT16_RS04695	COG2070	2-Nitropropane dioxygenase
AOT16_RS04725	COG1215	transferase activity, transferring glycosyl groups
AOT16_RS04740	COG0415	Belongs to the DNA photolyase family
AOT16_RS04750	COG1252	NADH dehydrogenase
AOT16_RS04755	COG1686	Belongs to the peptidase S11 family
AOT16_RS04770	COG1187	pseudouridine synthase activity
AOT16_RS04790	COG0477	Major facilitator Superfamily
AOT16_RS04795	COG0583	DNA-binding transcription factor activity
AOT16_RS04800	COG1823	symporter activity
AOT16_RS04810	COG0612	Peptidase, M16
AOT16_RS04835	COG0352	thiamine-phosphate diphosphorylase activity
AOT16_RS04870	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT16_RS04885	COG1309	transcriptional regulator
AOT16_RS04895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AOT16_RS04900	COG0076	glutamate decarboxylase activity
AOT16_RS04910	COG1522	sequence-specific DNA binding
AOT16_RS04915	COG3961	Belongs to the TPP enzyme family
AOT16_RS04920	COG1113	amino acid transport
AOT16_RS04925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AOT16_RS04930	COG0573	inorganic phosphate transmembrane transporter activity
AOT16_RS04940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AOT16_RS04945	COG0616	signal peptide processing
AOT16_RS04980	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AOT16_RS04985	COG1686	Belongs to the peptidase S11 family
AOT16_RS05010	COG0583	DNA-binding transcription factor activity
AOT16_RS05015	COG1067	ATP-dependent peptidase activity
AOT16_RS05060	COG1966	Carbon starvation protein
AOT16_RS05065	COG2879	small protein
AOT16_RS05105	COG2508	Transcriptional regulator
AOT16_RS05105	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
AOT16_RS05125	COG1113	amino acid transport
AOT16_RS05130	COG0583	DNA-binding transcription factor activity
AOT16_RS05135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_RS05140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_RS05150	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS05155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_RS05160	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AOT16_RS05160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT16_RS05195	COG2814	Major facilitator Superfamily
AOT16_RS05200	COG4948	Mandelate Racemase Muconate Lactonizing
AOT16_RS05210	COG1309	transcriptional regulator
AOT16_RS05230	COG1741	Belongs to the pirin family
AOT16_RS05240	COG2964	Protein conserved in bacteria
AOT16_RS05255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT16_RS05260	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOT16_RS05265	COG4605	iron ion homeostasis
AOT16_RS05270	COG4604	ABC transporter, ATP-binding protein
AOT16_RS05275	COG4607	ABC-type enterochelin transport system periplasmic component
AOT16_RS05290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AOT16_RS05295	COG1021	2,3-dihydroxybenzoate-AMP ligase
AOT16_RS05300	COG1535	isochorismatase
AOT16_RS05300	COG3433	isochorismatase activity
AOT16_RS05310	COG1132	(ABC) transporter
AOT16_RS05315	COG1132	(ABC) transporter
AOT16_RS05320	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AOT16_RS05330	COG1169	isochorismate synthase
AOT16_RS05345	COG3739	integral membrane protein
AOT16_RS05395	COG0302	gtp cyclohydrolase
AOT16_RS05405	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AOT16_RS05435	COG0308	aminopeptidase N
AOT16_RS05440	COG0512	Glutamine amidotransferase of anthranilate synthase
AOT16_RS05455	COG0174	glutamine synthetase
AOT16_RS05465	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AOT16_RS05500	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AOT16_RS05505	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AOT16_RS05510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AOT16_RS05530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AOT16_RS05535	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AOT16_RS05540	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AOT16_RS05555	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS05560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOT16_RS05565	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT16_RS05575	COG2223	nitrite transmembrane transporter activity
AOT16_RS05585	COG0024	Methionine aminopeptidase
AOT16_RS05590	COG0052	Belongs to the universal ribosomal protein uS2 family
AOT16_RS05605	COG2207	Transcriptional regulator
AOT16_RS05630	COG2951	lytic endotransglycosylase activity
AOT16_RS05635	COG0772	Belongs to the SEDS family
AOT16_RS05650	COG0842	Transport permease protein
AOT16_RS05655	COG1131	(ABC) transporter
AOT16_RS05700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_RS05715	COG4215	(ABC) transporter
AOT16_RS05720	COG4160	amino acid transport
AOT16_RS05725	COG4598	ABC transporter
AOT16_RS05735	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOT16_RS05740	COG0826	peptidase U32
AOT16_RS05745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_RS05760	COG1720	tRNA m6t6A37 methyltransferase activity
AOT16_RS05770	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AOT16_RS05785	COG0642	Histidine kinase
AOT16_RS05795	COG0494	nUDIX hydrolase
AOT16_RS05805	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AOT16_RS05810	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AOT16_RS05815	COG3139	Protein of unknown function (DUF1315)
AOT16_RS05820	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AOT16_RS05830	COG1301	dicarboxylic acid transport
AOT16_RS05835	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS05840	COG2819	hydrolase of the alpha beta superfamily
AOT16_RS05850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AOT16_RS05860	COG2195	Cleaves the N-terminal amino acid of tripeptides
AOT16_RS05865	COG1234	tRNA 3'-trailer cleavage
AOT16_RS05895	COG2363	Small membrane protein
AOT16_RS05915	COG0513	Belongs to the DEAD box helicase family
AOT16_RS05925	COG0778	Nitroreductase
AOT16_RS05955	COG1286	toxin biosynthetic process
AOT16_RS05980	COG4783	chaperone-mediated protein folding
AOT16_RS05985	COG1610	YqeY-like protein
AOT16_RS06085	COG3111	PFAM Bacterial OB fold (BOF) protein
AOT16_RS06110	COG3243	poly(R)-hydroxyalkanoic acid synthase
AOT16_RS06115	COG0786	glutamate:sodium symporter activity
AOT16_RS06125	COG2186	Transcriptional regulator
AOT16_RS06175	COG0477	Major facilitator Superfamily
AOT16_RS06205	COG2985	domain, Protein
AOT16_RS06215	COG2995	paraquat-inducible protein a
AOT16_RS06220	COG3008	intermembrane lipid transfer
AOT16_RS06220	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AOT16_RS06230	COG1794	racemase activity, acting on amino acids and derivatives
AOT16_RS06335	COG0488	(ABC) transporter
AOT16_RS06340	COG3173	Aminoglycoside phosphotransferase
AOT16_RS06350	COG2433	Pfam Transposase IS66
AOT16_RS06390	COG1301	dicarboxylic acid transport
AOT16_RS06400	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT16_RS06405	COG2011	ABC-type metal ion transport system permease component
AOT16_RS06410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOT16_RS06415	COG1464	Belongs to the NlpA lipoprotein family
AOT16_RS06420	COG0151	Belongs to the GarS family
AOT16_RS06425	COG0138	bifunctional purine biosynthesis protein purh
AOT16_RS06430	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AOT16_RS06460	COG2308	Evidence 4 Homologs of previously reported genes of
AOT16_RS06470	COG1305	Transglutaminase-like
AOT16_RS06480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AOT16_RS06485	COG0305	Participates in initiation and elongation during chromosome replication
AOT16_RS06510	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AOT16_RS06520	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AOT16_RS06525	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AOT16_RS06550	COG0726	polysaccharide deacetylase
AOT16_RS06550	COG1649	PFAM Uncharacterised BCR, COG1649
AOT16_RS06555	COG1215	transferase activity, transferring glycosyl groups
AOT16_RS06560	COG3658	cytochrome
AOT16_RS06570	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOT16_RS06590	COG0583	DNA-binding transcription factor activity
AOT16_RS06610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT16_RS06615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT16_RS06630	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS06635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AOT16_RS06640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_RS06665	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AOT16_RS06670	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AOT16_RS06680	COG2205	protein histidine kinase activity
AOT16_RS06685	COG0745	RESPONSE REGULATOR receiver
AOT16_RS06690	COG0174	glutamine synthetase
AOT16_RS06710	COG0729	surface antigen
AOT16_RS06740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOT16_RS06745	COG2814	Major facilitator Superfamily
AOT16_RS06760	COG0583	DNA-binding transcription factor activity
AOT16_RS06775	COG1187	pseudouridine synthase activity
AOT16_RS06795	COG0802	atpase or kinase
AOT16_RS06800	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AOT16_RS06810	COG1923	regulation of RNA biosynthetic process
AOT16_RS06815	COG0697	spore germination
AOT16_RS06830	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT16_RS06840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOT16_RS06845	COG0519	Catalyzes the synthesis of GMP from XMP
AOT16_RS06845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOT16_RS06850	COG4302	ethanolamine ammonia-lyase activity
AOT16_RS06855	COG4303	Ethanolamine ammonia lyase large subunit
AOT16_RS06860	COG0531	amino acid
AOT16_RS06880	COG1454	alcohol dehydrogenase
AOT16_RS06885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOT16_RS06895	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AOT16_RS06915	COG0308	aminopeptidase N
AOT16_RS06925	COG4221	oxidoreductase activity
AOT16_RS06935	COG1605	Chorismate mutase
AOT16_RS06960	COG1309	transcriptional regulator
AOT16_RS06970	COG0668	transmembrane transport
AOT16_RS07015	COG4773	Receptor
AOT16_RS07030	COG0488	(ABC) transporter
AOT16_RS07035	COG0589	response to stress
AOT16_RS07050	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AOT16_RS07060	COG3135	benzoate transporter
AOT16_RS07065	COG1522	sequence-specific DNA binding
AOT16_RS07075	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AOT16_RS07080	COG0583	DNA-binding transcription factor activity
AOT16_RS07090	COG0183	Belongs to the thiolase family
AOT16_RS07100	COG2030	dehydratase
AOT16_RS07105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOT16_RS07120	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AOT16_RS07130	COG0824	Thioesterase
AOT16_RS07135	COG1454	alcohol dehydrogenase
AOT16_RS07145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AOT16_RS07165	COG0069	glutamate synthase activity
AOT16_RS07585	COG2814	Major facilitator Superfamily
AOT16_RS07600	COG0511	ligase activity, forming carbon-carbon bonds
AOT16_RS07615	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT16_RS07615	COG1116	anion transmembrane transporter activity
AOT16_RS07620	COG0745	RESPONSE REGULATOR receiver
AOT16_RS07630	COG2146	nitrite reductase [NAD(P)H] activity
AOT16_RS07630	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_RS07635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_RS07640	COG0243	molybdopterin cofactor binding
AOT16_RS07650	COG0243	molybdopterin cofactor binding
AOT16_RS07655	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AOT16_RS07670	COG0521	Mo-molybdopterin cofactor biosynthetic process
AOT16_RS07670	COG0315	cyclic pyranopterin monophosphate synthase activity
AOT16_RS07675	COG0303	'Molybdopterin
AOT16_RS07685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_RS07690	COG0697	spore germination
AOT16_RS07710	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AOT16_RS07715	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOT16_RS07810	COG2204	response regulator
AOT16_RS07815	COG3852	Histidine kinase
AOT16_RS07835	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AOT16_RS07840	COG0575	Belongs to the CDS family
AOT16_RS07875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT16_RS07890	COG2137	regulation of response to DNA damage stimulus
AOT16_RS07900	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AOT16_RS07905	COG1011	Hydrolase
AOT16_RS07930	COG1522	sequence-specific DNA binding
AOT16_RS07940	COG1113	amino acid transport
AOT16_RS07955	COG0659	secondary active sulfate transmembrane transporter activity
AOT16_RS07960	COG2135	peptidase activity
AOT16_RS07975	COG5001	Diguanylate cyclase
AOT16_RS07975	COG3300	MHYT domain
AOT16_RS07995	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AOT16_RS07995	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT16_RS07995	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AOT16_RS08000	COG1105	Belongs to the carbohydrate kinase PfkB family
AOT16_RS08005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AOT16_RS08005	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT16_RS08035	COG0024	Methionine aminopeptidase
AOT16_RS08040	COG0583	DNA-binding transcription factor activity
AOT16_RS08050	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AOT16_RS08055	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AOT16_RS08060	COG0517	IMP dehydrogenase activity
AOT16_RS08060	COG0516	GMP reductase activity
AOT16_RS08090	COG0552	protein localization to endoplasmic reticulum
AOT16_RS08100	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AOT16_RS08115	COG4890	Cyd operon protein YbgT
AOT16_RS08120	COG1294	oxidase, subunit
AOT16_RS08135	COG1585	Membrane protein implicated in regulation of membrane protease activity
AOT16_RS08145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AOT16_RS08150	COG4774	siderophore transport
AOT16_RS08165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AOT16_RS08170	COG0569	domain protein
AOT16_RS08175	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AOT16_RS08205	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AOT16_RS08210	COG0542	response to heat
AOT16_RS08235	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_RS08235	COG1902	pentaerythritol trinitrate reductase activity
AOT16_RS08280	COG2323	membrane
AOT16_RS08285	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AOT16_RS08295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOT16_RS08300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT16_RS08305	COG0183	Belongs to the thiolase family
AOT16_RS08310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AOT16_RS08315	COG0596	Alpha beta hydrolase
AOT16_RS08320	COG2271	Major facilitator Superfamily
AOT16_RS08325	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOT16_RS08330	COG3485	protocatechuate 3,4-dioxygenase
AOT16_RS08335	COG3485	protocatechuate 3,4-dioxygenase
AOT16_RS08340	COG0710	3-dehydroquinate dehydratase activity
AOT16_RS08345	COG3420	alginic acid biosynthetic process
AOT16_RS08350	COG3659	wide pore channel activity
AOT16_RS08355	COG4993	Dehydrogenase
AOT16_RS08365	COG2391	methyltransferase activity
AOT16_RS08380	COG1414	Transcriptional regulator
AOT16_RS08385	COG0583	DNA-binding transcription factor activity
AOT16_RS08390	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS08415	COG2814	Major facilitator Superfamily
AOT16_RS08425	COG0154	amidase activity
AOT16_RS08445	COG4638	Rieske (2fe-2S)
AOT16_RS08455	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS08465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_RS08475	COG3733	amine oxidase
AOT16_RS08485	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS08495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOT16_RS08500	COG0183	Belongs to the thiolase family
AOT16_RS08505	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT16_RS08510	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOT16_RS08520	COG4829	muconolactone delta-isomerase
AOT16_RS08525	COG4948	Mandelate Racemase Muconate Lactonizing
AOT16_RS08530	COG0583	DNA-binding transcription factor activity
AOT16_RS08540	COG2186	Transcriptional regulator
AOT16_RS08560	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS08580	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS08590	COG3829	transcription factor binding
AOT16_RS08600	COG3162	membrane
AOT16_RS08615	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS08630	COG0753	catalase activity
AOT16_RS08655	COG1846	Transcriptional regulator
AOT16_RS08660	COG1902	pentaerythritol trinitrate reductase activity
AOT16_RS08660	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_RS08670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AOT16_RS08700	COG1309	transcriptional regulator
AOT16_RS08710	COG1335	isochorismatase
AOT16_RS08715	COG0583	DNA-binding transcription factor activity
AOT16_RS08725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT16_RS08725	COG0475	glutathione-regulated potassium exporter activity
AOT16_RS08735	COG1473	amidohydrolase
AOT16_RS08750	COG2831	hemolysin activation secretion protein
AOT16_RS08755	COG3210	domain, Protein
AOT16_RS08780	COG2188	Transcriptional regulator
AOT16_RS08810	COG0583	DNA-binding transcription factor activity
AOT16_RS08840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOT16_RS08860	COG1566	PFAM secretion protein HlyD family protein
AOT16_RS08875	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS08880	COG0129	dihydroxy-acid dehydratase activity
AOT16_RS08890	COG0583	DNA-binding transcription factor activity
AOT16_RS08895	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AOT16_RS08905	COG2084	Dehydrogenase
AOT16_RS08910	COG2207	Transcriptional regulator
AOT16_RS08925	COG1064	alcohol dehydrogenase
AOT16_RS08935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AOT16_RS08940	COG1120	ATPase activity
AOT16_RS08960	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOT16_RS09080	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AOT16_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS09150	COG2207	Transcriptional regulator
AOT16_RS09160	COG2205	protein histidine kinase activity
AOT16_RS09165	COG0745	RESPONSE REGULATOR receiver
AOT16_RS09170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_RS09175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT16_RS09180	COG1538	Outer membrane efflux protein
AOT16_RS09190	COG2072	flavoprotein involved in K transport
AOT16_RS09210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT16_RS09230	COG3539	Fimbrial protein
AOT16_RS09270	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AOT16_RS09280	COG0753	catalase activity
AOT16_RS09295	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AOT16_RS09355	COG3433	isochorismatase activity
AOT16_RS09355	COG1535	isochorismatase
AOT16_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS09365	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AOT16_RS09370	COG4149	molybdate abc transporter
AOT16_RS09375	COG0725	ABC transporter, periplasmic molybdate-binding protein
AOT16_RS09385	COG4638	Rieske (2fe-2S)
AOT16_RS09390	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AOT16_RS09395	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT16_RS09395	COG0543	2 iron, 2 sulfur cluster binding
AOT16_RS09420	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS09435	COG2207	Transcriptional regulator
AOT16_RS09450	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS09455	COG2610	gluconate transmembrane transporter activity
AOT16_RS09465	COG0583	DNA-binding transcription factor activity
AOT16_RS09475	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT16_RS09480	COG2031	fatty acid transporter
AOT16_RS09485	COG0183	Belongs to the thiolase family
AOT16_RS09490	COG0583	DNA-binding transcription factor activity
AOT16_RS09495	COG0583	DNA-binding transcription factor activity
AOT16_RS09510	COG1027	Aspartate ammonia-lyase
AOT16_RS09520	COG0477	Major facilitator Superfamily
AOT16_RS09540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT16_RS09545	COG4521	taurine ABC transporter
AOT16_RS09560	COG2188	Transcriptional regulator
AOT16_RS09570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AOT16_RS09575	COG1733	regulation of RNA biosynthetic process
AOT16_RS09580	COG2207	Transcriptional regulator
AOT16_RS09580	COG3708	Transcriptional regulator
AOT16_RS09595	COG0730	response to heat
AOT16_RS09605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT16_RS09605	COG3453	Protein conserved in bacteria
AOT16_RS09615	COG3781	membrane
AOT16_RS09620	COG1063	alcohol dehydrogenase
AOT16_RS09630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AOT16_RS09635	COG0508	dehydrogenase complex catalyzes the overall conversion of
AOT16_RS09640	COG0022	dehydrogenase e1 component
AOT16_RS09645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AOT16_RS09650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AOT16_RS09665	COG3706	GGDEF domain
AOT16_RS09680	COG0133	tryptophan synthase activity
AOT16_RS09690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AOT16_RS09720	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AOT16_RS09745	COG2226	methyltransferase
AOT16_RS09800	COG0842	Transport permease protein
AOT16_RS09805	COG0842	Transport permease protein
AOT16_RS09810	COG1131	(ABC) transporter
AOT16_RS09825	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AOT16_RS09830	COG4773	Receptor
AOT16_RS09850	COG0730	response to heat
AOT16_RS09855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AOT16_RS09875	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AOT16_RS09930	COG4264	IucA IucC family
AOT16_RS09935	COG4264	IucA IucC family
AOT16_RS09955	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AOT16_RS09970	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS09975	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS09980	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AOT16_RS09985	COG2207	Transcriptional regulator
AOT16_RS09990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOT16_RS09995	COG0776	regulation of translation
AOT16_RS10020	COG0822	iron-sulfur transferase activity
AOT16_RS10025	COG0316	Belongs to the HesB IscA family
AOT16_RS10055	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AOT16_RS10075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AOT16_RS10080	COG0702	epimerase
AOT16_RS10115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AOT16_RS10125	COG0339	signal peptide processing
AOT16_RS10170	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AOT16_RS10175	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AOT16_RS10205	COG0776	regulation of translation
AOT16_RS10270	COG0084	hydrolase, TatD family'
AOT16_RS10290	COG1663	tetraacyldisaccharide 4'-kinase activity
AOT16_RS10295	COG1132	(ABC) transporter
AOT16_RS10305	COG0811	peptide transport
AOT16_RS10310	COG1475	DNA binding
AOT16_RS10315	COG1192	Involved in chromosome partitioning
AOT16_RS10325	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AOT16_RS10340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AOT16_RS10345	COG0191	fructose-bisphosphate aldolase activity
AOT16_RS10365	COG0424	maF-like protein
AOT16_RS10370	COG2850	peptidyl-arginine hydroxylation
AOT16_RS10380	COG0640	Transcriptional regulator
AOT16_RS10390	COG3619	membrane
AOT16_RS10395	COG3122	Protein conserved in bacteria
AOT16_RS10400	COG1132	(ABC) transporter
AOT16_RS10420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AOT16_RS10425	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AOT16_RS10435	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOT16_RS10435	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AOT16_RS10435	COG0506	proline dehydrogenase activity
AOT16_RS10440	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AOT16_RS10455	COG3698	Phosphodiester glycosidase
AOT16_RS10475	COG1765	OsmC-like protein
AOT16_RS10500	COG2353	YceI-like domain
AOT16_RS10510	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AOT16_RS10555	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AOT16_RS10555	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AOT16_RS10580	COG3539	Fimbrial protein
AOT16_RS10585	COG3121	Chaperone
AOT16_RS10615	COG0697	spore germination
AOT16_RS10625	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AOT16_RS10635	COG0583	DNA-binding transcription factor activity
AOT16_RS10655	COG1309	transcriptional regulator
AOT16_RS10670	COG1522	sequence-specific DNA binding
AOT16_RS10680	COG1126	abc transporter atp-binding protein
AOT16_RS10685	COG0765	amino acid transport
AOT16_RS10690	COG0765	amino acid transport
AOT16_RS10720	COG1464	Belongs to the NlpA lipoprotein family
AOT16_RS10730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AOT16_RS10735	COG2011	ABC-type metal ion transport system permease component
AOT16_RS10740	COG0012	GTP binding
AOT16_RS10765	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AOT16_RS10805	COG0386	Belongs to the glutathione peroxidase family
AOT16_RS10815	COG0436	Aminotransferase
AOT16_RS10855	COG3634	alkyl hydroperoxide reductase activity
AOT16_RS10870	COG0583	DNA-binding transcription factor activity
AOT16_RS10875	COG0798	PFAM Bile acid sodium symporter
AOT16_RS10880	COG0640	Transcriptional regulator
AOT16_RS10895	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AOT16_RS10905	COG0583	DNA-binding transcription factor activity
AOT16_RS10915	COG1953	Uracil, thiamine, allantoin
AOT16_RS10925	COG2175	clavaminate synthase activity
AOT16_RS10930	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT16_RS10935	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AOT16_RS10940	COG4521	taurine ABC transporter
AOT16_RS10950	COG0477	Major facilitator Superfamily
AOT16_RS10975	COG1271	oxidase subunit
AOT16_RS10980	COG1294	oxidase, subunit
AOT16_RS10985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_RS11005	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AOT16_RS11025	COG3052	prosthetic group binding
AOT16_RS11030	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AOT16_RS11040	COG2814	Major facilitator Superfamily
AOT16_RS11060	COG1346	cytolysis
AOT16_RS11070	COG0583	DNA-binding transcription factor activity
AOT16_RS11075	COG0625	glutathione transferase activity
AOT16_RS11080	COG0625	glutathione transferase activity
AOT16_RS11085	COG0583	DNA-binding transcription factor activity
AOT16_RS11100	COG1045	serine acetyltransferase
AOT16_RS11105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AOT16_RS11110	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AOT16_RS11115	COG1280	lysine exporter protein (LysE YggA)
AOT16_RS11125	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT16_RS11130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT16_RS11135	COG1126	abc transporter atp-binding protein
AOT16_RS11140	COG0765	amino acid transport
AOT16_RS11145	COG0765	amino acid transport
AOT16_RS11180	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AOT16_RS11200	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS11245	COG0583	DNA-binding transcription factor activity
AOT16_RS11265	COG0318	PFAM AMP-dependent synthetase and ligase
AOT16_RS11270	COG1309	transcriptional regulator
AOT16_RS11275	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS11280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AOT16_RS11285	COG1024	Enoyl-CoA hydratase
AOT16_RS11290	COG4770	biotin carboxylase activity
AOT16_RS11300	COG0583	DNA-binding transcription factor activity
AOT16_RS11315	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS11325	COG2814	Major facilitator Superfamily
AOT16_RS11335	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AOT16_RS11340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AOT16_RS11345	COG2814	Major facilitator Superfamily
AOT16_RS11350	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS11355	COG1024	Enoyl-CoA hydratase
AOT16_RS11360	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS11365	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOT16_RS11370	COG0183	Belongs to the thiolase family
AOT16_RS11380	COG2814	Major facilitator Superfamily
AOT16_RS11390	COG1024	Enoyl-CoA hydratase
AOT16_RS11405	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS11410	COG2814	Major facilitator Superfamily
AOT16_RS11415	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AOT16_RS11420	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AOT16_RS11435	COG3842	ATPase activity
AOT16_RS11440	COG1840	ABC-type Fe3 transport system, periplasmic component
AOT16_RS11450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_RS11455	COG1414	Transcriptional regulator
AOT16_RS11465	COG0583	DNA-binding transcription factor activity
AOT16_RS11470	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AOT16_RS11475	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS11485	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AOT16_RS11490	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS11495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOT16_RS11520	COG3038	cytochrome b561
AOT16_RS11525	COG0753	catalase activity
AOT16_RS11565	COG2050	protein possibly involved in aromatic compounds catabolism
AOT16_RS11575	COG3327	negative regulation of DNA-templated transcription, initiation
AOT16_RS11580	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AOT16_RS11585	COG0183	Belongs to the thiolase family
AOT16_RS11590	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOT16_RS11595	COG1024	Enoyl-CoA hydratase
AOT16_RS11600	COG1024	Enoyl-CoA hydratase
AOT16_RS11605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AOT16_RS11610	COG2151	metal-sulfur cluster biosynthetic enzyme
AOT16_RS11615	COG3396	Phenylacetate-CoA oxygenase
AOT16_RS11620	COG3460	Phenylacetate-CoA oxygenase
AOT16_RS11625	COG3396	Phenylacetate-CoA oxygenase
AOT16_RS11630	COG2030	dehydratase
AOT16_RS11630	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS11635	COG1760	l-serine dehydratase
AOT16_RS11640	COG0531	amino acid
AOT16_RS11645	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS11660	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_RS11670	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AOT16_RS11690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT16_RS11705	COG0789	Transcriptional regulator
AOT16_RS11730	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AOT16_RS11745	COG2807	transmembrane transport
AOT16_RS11750	COG0590	tRNA wobble adenosine to inosine editing
AOT16_RS11870	COG1116	anion transmembrane transporter activity
AOT16_RS11875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AOT16_RS11885	COG0864	Transcriptional regulator
AOT16_RS11900	COG2249	NAD(P)H dehydrogenase (quinone) activity
AOT16_RS11905	COG0439	Biotin carboxylase
AOT16_RS11920	COG1063	alcohol dehydrogenase
AOT16_RS11930	COG1309	transcriptional regulator
AOT16_RS11960	COG0038	chloride channel
AOT16_RS11965	COG4770	biotin carboxylase activity
AOT16_RS11985	COG1914	H( )-stimulated, divalent metal cation uptake system
AOT16_RS11990	COG0583	DNA-binding transcription factor activity
AOT16_RS12045	COG1250	3-hydroxyacyl-CoA dehydrogenase
AOT16_RS12065	COG2814	Major facilitator Superfamily
AOT16_RS12080	COG1560	Kdo2-lipid A biosynthetic process
AOT16_RS12090	COG5006	permease, DMT superfamily
AOT16_RS12095	COG1522	sequence-specific DNA binding
AOT16_RS12110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AOT16_RS12120	COG4122	O-methyltransferase activity
AOT16_RS12150	COG1538	Outer membrane efflux protein
AOT16_RS12155	COG1137	ATPase activity
AOT16_RS12160	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AOT16_RS12170	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AOT16_RS12175	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AOT16_RS12175	COG0517	IMP dehydrogenase activity
AOT16_RS12215	COG2814	Major facilitator Superfamily
AOT16_RS12250	COG1278	Cold shock
AOT16_RS12255	COG1280	lysine exporter protein (LysE YggA)
AOT16_RS12290	COG1570	exodeoxyribonuclease VII activity
AOT16_RS12345	COG0583	DNA-binding transcription factor activity
AOT16_RS12350	COG4638	Rieske (2fe-2S)
AOT16_RS12355	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AOT16_RS12360	COG0633	Ferredoxin
AOT16_RS12360	COG0543	2 iron, 2 sulfur cluster binding
AOT16_RS12365	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS12370	COG3135	benzoate transporter
AOT16_RS12375	COG2814	Major facilitator Superfamily
AOT16_RS12390	COG1643	Atp-dependent helicase
AOT16_RS12395	COG0450	alkyl hydroperoxide reductase
AOT16_RS12405	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AOT16_RS12415	COG3634	alkyl hydroperoxide reductase activity
AOT16_RS12435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AOT16_RS12440	COG0625	glutathione transferase activity
AOT16_RS12450	COG2885	chlorophyll binding
AOT16_RS12485	COG0542	response to heat
AOT16_RS12515	COG1765	OsmC-like protein
AOT16_RS12540	COG0667	Aldo Keto reductase
AOT16_RS12555	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AOT16_RS12565	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AOT16_RS12575	COG0527	aspartate kinase activity
AOT16_RS12585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AOT16_RS12595	COG3038	cytochrome b561
AOT16_RS12600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AOT16_RS12605	COG2252	PERMEase
AOT16_RS12615	COG2072	flavoprotein involved in K transport
AOT16_RS12630	COG1741	Belongs to the pirin family
AOT16_RS12635	COG1309	transcriptional regulator
AOT16_RS12645	COG0300	oxidoreductase activity
AOT16_RS12650	COG2072	flavoprotein involved in K transport
AOT16_RS12685	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AOT16_RS12725	COG1113	amino acid transport
AOT16_RS12745	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS12765	COG0531	amino acid
AOT16_RS12775	COG1113	amino acid transport
AOT16_RS12820	COG3209	COG3209 Rhs family protein
AOT16_RS12850	COG4269	membrane
AOT16_RS12865	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_RS12865	COG1902	pentaerythritol trinitrate reductase activity
AOT16_RS12875	COG3706	GGDEF domain
AOT16_RS12875	COG4251	negative regulation of phosphorylation
AOT16_RS12875	COG2203	Gaf domain
AOT16_RS12875	COG5001	Diguanylate cyclase
AOT16_RS12885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT16_RS12905	COG4172	Belongs to the ABC transporter superfamily
AOT16_RS12910	COG4239	(ABC) transporter, permease
AOT16_RS12915	COG4174	ABC transporter (Permease)
AOT16_RS12925	COG1388	LysM domain
AOT16_RS12925	COG0741	lytic transglycosylase activity
AOT16_RS12925	COG1388	LysM domain
AOT16_RS12925	COG0741	lytic transglycosylase activity
AOT16_RS12930	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT16_RS12970	COG0583	DNA-binding transcription factor activity
AOT16_RS12975	COG1279	arginine transmembrane transporter activity
AOT16_RS12995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_RS13000	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_RS13040	COG2194	sulfuric ester hydrolase activity
AOT16_RS13090	COG0739	heme binding
AOT16_RS13410	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AOT16_RS13435	COG3384	dioxygenase
AOT16_RS13445	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AOT16_RS13450	COG2878	Part of a membrane complex involved in electron transport
AOT16_RS13455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AOT16_RS13475	COG0768	penicillin binding
AOT16_RS13480	COG0742	ribosomal rna small subunit methyltransferase
AOT16_RS13495	COG0830	nickel cation binding
AOT16_RS13505	COG0804	urea catabolic process
AOT16_RS13545	COG1253	flavin adenine dinucleotide binding
AOT16_RS13555	COG2851	Citrate transporter
AOT16_RS13600	COG1773	rubredoxin
AOT16_RS13605	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AOT16_RS13615	COG0583	DNA-binding transcription factor activity
AOT16_RS13640	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AOT16_RS13645	COG4181	ATPase activity
AOT16_RS13690	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AOT16_RS13705	COG0306	phosphate transporter
AOT16_RS13715	COG3958	Transketolase
AOT16_RS13720	COG3959	Transketolase, thiamine diphosphate binding domain
AOT16_RS13725	COG2271	Major facilitator Superfamily
AOT16_RS13730	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS13735	COG0583	DNA-binding transcription factor activity
AOT16_RS13755	COG2223	nitrite transmembrane transporter activity
AOT16_RS13760	COG2207	Transcriptional regulator
AOT16_RS13765	COG2066	Belongs to the glutaminase family
AOT16_RS13770	COG0242	peptide deformylase activity
AOT16_RS13775	COG0477	Major facilitator Superfamily
AOT16_RS13785	COG0028	Belongs to the TPP enzyme family
AOT16_RS13800	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS13805	COG2267	carboxylic ester hydrolase activity
AOT16_RS13815	COG2271	Major facilitator Superfamily
AOT16_RS13820	COG0446	pyridine nucleotide-disulphide oxidoreductase
AOT16_RS13830	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS13850	COG1414	Transcriptional regulator
AOT16_RS13865	COG1024	Enoyl-CoA hydratase
AOT16_RS13875	COG1215	transferase activity, transferring glycosyl groups
AOT16_RS13880	COG0726	polysaccharide deacetylase
AOT16_RS13880	COG1649	PFAM Uncharacterised BCR, COG1649
AOT16_RS13890	COG4681	YaeQ
AOT16_RS13900	COG0523	cobalamin synthesis protein
AOT16_RS13910	COG1607	acyl-coa hydrolase
AOT16_RS13920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_RS13925	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AOT16_RS13930	COG1309	transcriptional regulator
AOT16_RS13955	COG2040	homocysteine
AOT16_RS13960	COG0531	amino acid
AOT16_RS13985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT16_RS13990	COG0477	Major facilitator Superfamily
AOT16_RS14110	COG0592	DNA-directed DNA polymerase activity
AOT16_RS14150	COG2026	Addiction module toxin, RelE StbE family
AOT16_RS14300	COG3755	Protein conserved in bacteria
AOT16_RS14345	COG1484	DNA-dependent DNA replication
AOT16_RS14435	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AOT16_RS14500	COG0405	Gamma-glutamyltransferase
AOT16_RS14505	COG2814	Major facilitator Superfamily
AOT16_RS14515	COG2050	protein possibly involved in aromatic compounds catabolism
AOT16_RS14530	COG1090	epimerase
AOT16_RS14550	COG0420	3'-5' exonuclease activity
AOT16_RS14575	COG0735	belongs to the Fur family
AOT16_RS14580	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AOT16_RS14605	COG0121	glutamine amidotransferase
AOT16_RS14620	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT16_RS14630	COG0210	DNA helicase
AOT16_RS14635	COG2885	chlorophyll binding
AOT16_RS14640	COG0204	Acyl-transferase
AOT16_RS14655	COG2894	cell division
AOT16_RS14675	COG1280	lysine exporter protein (LysE YggA)
AOT16_RS14680	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AOT16_RS14680	COG1674	ftsk spoiiie
AOT16_RS14685	COG0492	ferredoxin-NADP+ reductase activity
AOT16_RS14690	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AOT16_RS14700	COG0456	acetyltransferase
AOT16_RS14745	COG1981	membrane
AOT16_RS14760	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AOT16_RS14760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOT16_RS14780	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS14790	COG0657	acetylesterase activity
AOT16_RS14800	COG0473	3-isopropylmalate dehydrogenase activity
AOT16_RS14805	COG0583	DNA-binding transcription factor activity
AOT16_RS14825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AOT16_RS14850	COG0564	pseudouridine synthase activity
AOT16_RS14860	COG0358	DNA primase activity
AOT16_RS14875	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AOT16_RS14905	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AOT16_RS14935	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AOT16_RS14945	COG0352	thiamine-phosphate diphosphorylase activity
AOT16_RS14945	COG0351	phosphomethylpyrimidine kinase
AOT16_RS14945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AOT16_RS14950	COG1652	LysM domain
AOT16_RS14975	COG1399	metal-binding, possibly nucleic acid-binding protein
AOT16_RS14980	COG3101	peptidyl-lysine hydroxylation
AOT16_RS14985	COG0009	L-threonylcarbamoyladenylate synthase
AOT16_RS14990	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AOT16_RS14995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AOT16_RS15010	COG4106	trans-aconitate 2-methyltransferase activity
AOT16_RS15025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOT16_RS15025	COG2226	methyltransferase
AOT16_RS15025	COG0596	Alpha beta hydrolase
AOT16_RS15030	COG1877	trehalose-phosphatase activity
AOT16_RS15035	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AOT16_RS15040	COG2223	nitrite transmembrane transporter activity
AOT16_RS15060	COG1196	nuclear chromosome segregation
AOT16_RS15070	COG0730	response to heat
AOT16_RS15085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AOT16_RS15095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOT16_RS15150	COG0489	protein tyrosine kinase activity
AOT16_RS15160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT16_RS15160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT16_RS15190	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AOT16_RS15195	COG2081	HI0933 family
AOT16_RS15200	COG0668	transmembrane transport
AOT16_RS15220	COG0583	DNA-binding transcription factor activity
AOT16_RS15240	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AOT16_RS15245	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOT16_RS15275	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AOT16_RS15315	COG0745	RESPONSE REGULATOR receiver
AOT16_RS15335	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AOT16_RS15345	COG2205	protein histidine kinase activity
AOT16_RS15415	COG4993	Dehydrogenase
AOT16_RS15435	COG0384	phenazine biosynthesis protein PhzF
AOT16_RS15465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AOT16_RS15480	COG0583	DNA-binding transcription factor activity
AOT16_RS15510	COG0583	DNA-binding transcription factor activity
AOT16_RS15530	COG0583	DNA-binding transcription factor activity
AOT16_RS15535	COG1053	succinate dehydrogenase
AOT16_RS15545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AOT16_RS15550	COG2814	Major facilitator Superfamily
AOT16_RS15555	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS15560	COG0583	DNA-binding transcription factor activity
AOT16_RS15565	COG1063	alcohol dehydrogenase
AOT16_RS15595	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AOT16_RS15600	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AOT16_RS15605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOT16_RS15620	COG3667	copper resistance
AOT16_RS15625	COG2132	Multicopper oxidase
AOT16_RS15635	COG0561	phosphatase activity
AOT16_RS15640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AOT16_RS15665	COG1214	PFAM Peptidase M22, glycoprotease
AOT16_RS15740	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AOT16_RS15750	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AOT16_RS15755	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AOT16_RS15760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AOT16_RS15820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AOT16_RS15830	COG1846	Transcriptional regulator
AOT16_RS15835	COG1764	response to oxidative stress
AOT16_RS15875	COG0037	tRNA processing
AOT16_RS15885	COG0248	Ppx GppA phosphatase
AOT16_RS15910	COG0072	phenylalanine-tRNA ligase activity
AOT16_RS15955	COG1238	metal cluster binding
AOT16_RS15960	COG0625	glutathione transferase activity
AOT16_RS15980	COG0318	PFAM AMP-dependent synthetase and ligase
AOT16_RS15985	COG3028	Belongs to the UPF0307 family
AOT16_RS15990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AOT16_RS16010	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AOT16_RS16015	COG0617	tRNA 3'-terminal CCA addition
AOT16_RS16020	COG1555	photosystem II stabilization
AOT16_RS16025	COG3956	TIGRFAM MazG family protein
AOT16_RS16035	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AOT16_RS16055	COG0784	Response regulator, receiver
AOT16_RS16055	COG2205	protein histidine kinase activity
AOT16_RS16055	COG5002	protein histidine kinase activity
AOT16_RS16060	COG1024	Enoyl-CoA hydratase
AOT16_RS16065	COG2084	Dehydrogenase
AOT16_RS16070	COG3622	Belongs to the hyi family
AOT16_RS16100	COG0697	spore germination
AOT16_RS16110	COG2814	Major facilitator Superfamily
AOT16_RS16115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AOT16_RS16125	COG0583	DNA-binding transcription factor activity
AOT16_RS16130	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AOT16_RS16145	COG0084	hydrolase, TatD family'
AOT16_RS16160	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AOT16_RS16195	COG0440	acetolactate synthase activity
AOT16_RS16200	COG0028	Belongs to the TPP enzyme family
AOT16_RS16230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AOT16_RS16235	COG1136	(ABC) transporter
AOT16_RS16235	COG0577	efflux transmembrane transporter activity
AOT16_RS16240	COG1538	Outer membrane efflux protein
AOT16_RS16255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AOT16_RS16260	COG1162	GTPase activity
AOT16_RS16270	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AOT16_RS16290	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AOT16_RS16295	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS16335	COG2986	histidine ammonia-lyase
AOT16_RS16350	COG0318	PFAM AMP-dependent synthetase and ligase
AOT16_RS16360	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT16_RS16405	COG1426	Protein conserved in bacteria
AOT16_RS16440	COG0793	Belongs to the peptidase S41A family
AOT16_RS16455	COG2267	carboxylic ester hydrolase activity
AOT16_RS16465	COG1012	belongs to the aldehyde dehydrogenase family
AOT16_RS16470	COG3265	gluconokinase activity
AOT16_RS16480	COG0800	Aldolase
AOT16_RS16490	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AOT16_RS16495	COG0857	belongs to the CobB CobQ family
AOT16_RS16495	COG0280	phosphate acetyltransferase
AOT16_RS16500	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AOT16_RS16500	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AOT16_RS16520	COG0740	serine-type endopeptidase activity
AOT16_RS16530	COG4774	siderophore transport
AOT16_RS16540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AOT16_RS16550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AOT16_RS16550	COG2813	Specifically methylates the guanine in position
AOT16_RS16650	COG0788	formyltetrahydrofolate deformylase activity
AOT16_RS16675	COG4651	solute:proton antiporter activity
AOT16_RS16675	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT16_RS16695	COG0724	RNA recognition motif
AOT16_RS16700	COG0210	DNA helicase
AOT16_RS16725	COG1733	regulation of RNA biosynthetic process
AOT16_RS16735	COG2900	Belongs to the SlyX family
AOT16_RS16740	COG0488	(ABC) transporter
AOT16_RS16745	COG1280	lysine exporter protein (LysE YggA)
AOT16_RS16750	COG1560	Kdo2-lipid A biosynthetic process
AOT16_RS16760	COG1301	dicarboxylic acid transport
AOT16_RS16815	COG0473	3-isopropylmalate dehydrogenase activity
AOT16_RS16880	COG0583	DNA-binding transcription factor activity
AOT16_RS16890	COG0625	glutathione transferase activity
AOT16_RS16895	COG2378	regulation of single-species biofilm formation
AOT16_RS16900	COG0546	phosphoglycolate phosphatase activity
AOT16_RS16915	COG1530	ribonuclease E activity
AOT16_RS16920	COG0318	PFAM AMP-dependent synthetase and ligase
AOT16_RS16935	COG0583	DNA-binding transcription factor activity
AOT16_RS16940	COG4221	oxidoreductase activity
AOT16_RS16945	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AOT16_RS16955	COG0534	Mate efflux family protein
AOT16_RS16970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AOT16_RS17005	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AOT16_RS17010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AOT16_RS17025	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AOT16_RS17035	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AOT16_RS17035	COG0644	oxidoreductase
AOT16_RS17040	COG0425	Belongs to the sulfur carrier protein TusA family
AOT16_RS17045	COG4535	Mg2 and Co2 transporter CorC
AOT16_RS17055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AOT16_RS17075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AOT16_RS17080	COG0475	glutathione-regulated potassium exporter activity
AOT16_RS17080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AOT16_RS17085	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AOT16_RS17095	COG0484	heat shock protein binding
AOT16_RS17100	COG0789	Transcriptional regulator
AOT16_RS17105	COG0598	Magnesium transport protein CorA
AOT16_RS17120	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AOT16_RS17125	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AOT16_RS17130	COG1074	ATP-dependent DNA helicase activity
AOT16_RS17135	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AOT16_RS17155	COG2226	methyltransferase
AOT16_RS17170	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AOT16_RS17175	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AOT16_RS17190	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AOT16_RS17190	COG2111	Na H antiporter
AOT16_RS17195	COG1006	Multisubunit Na H antiporter MnhC subunit
AOT16_RS17200	COG0651	ATP synthesis coupled electron transport
AOT16_RS17205	COG1863	multisubunit Na H antiporter MnhE subunit
AOT16_RS17210	COG2212	antiporter activity
AOT16_RS17215	COG1320	monovalent cation:proton antiporter activity
AOT16_RS17230	COG0195	Participates in both transcription termination and antitermination
AOT16_RS17280	COG0237	dephospho-CoA kinase activity
AOT16_RS17290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AOT16_RS17305	COG0497	DNA recombination
AOT16_RS17315	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AOT16_RS17345	COG2169	Transcriptional regulator
AOT16_RS17345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AOT16_RS17350	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AOT16_RS17415	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AOT16_RS17430	COG0326	Molecular chaperone. Has ATPase activity
AOT16_RS17445	COG2056	Na+-H+ antiporter family
AOT16_RS17450	COG0596	Alpha beta hydrolase
AOT16_RS17545	COG0546	phosphoglycolate phosphatase activity
AOT16_RS17550	COG1716	ATPase activity
AOT16_RS17595	COG0181	hydroxymethylbilane synthase activity
AOT16_RS17605	COG3275	phosphorelay sensor kinase activity
AOT16_RS17625	COG1538	Outer membrane efflux protein
AOT16_RS17630	COG0697	spore germination
AOT16_RS17655	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AOT16_RS17660	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AOT16_RS17665	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AOT16_RS17670	COG0772	Belongs to the SEDS family
AOT16_RS17695	COG4974	Belongs to the 'phage' integrase family
AOT16_RS17700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT16_RS17710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AOT16_RS17720	COG2197	response regulator
AOT16_RS17735	COG0793	Belongs to the peptidase S41A family
AOT16_RS17740	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AOT16_RS17745	COG0795	lipopolysaccharide-transporting ATPase activity
AOT16_RS17785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOT16_RS17785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AOT16_RS17795	COG0004	ammonium transporteR
AOT16_RS17800	COG0347	Belongs to the P(II) protein family
AOT16_RS17810	COG0606	chelatase, subunit chli
AOT16_RS17865	COG0659	secondary active sulfate transmembrane transporter activity
AOT16_RS17870	COG0589	response to stress
AOT16_RS17915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT16_RS17975	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AOT16_RS18005	COG0659	secondary active sulfate transmembrane transporter activity
AOT16_RS18010	COG0589	response to stress
AOT16_RS18040	COG0606	chelatase, subunit chli
AOT16_RS18045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AOT16_RS18055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AOT16_RS18070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AOT16_RS18085	COG0318	PFAM AMP-dependent synthetase and ligase
AOT16_RS18095	COG0477	Major facilitator Superfamily
AOT16_RS18100	COG2860	membrane
AOT16_RS18110	COG1253	flavin adenine dinucleotide binding
AOT16_RS18130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AOT16_RS18165	COG0655	NAD(P)H dehydrogenase (quinone) activity
AOT16_RS18175	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AOT16_RS18210	COG1309	transcriptional regulator
AOT16_RS18245	COG0758	DNA mediated transformation
AOT16_RS18255	COG0697	spore germination
AOT16_RS18260	COG1309	transcriptional regulator
AOT16_RS18275	COG0386	Belongs to the glutathione peroxidase family
AOT16_RS18340	COG1121	(ABC) transporter
AOT16_RS18345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AOT16_RS18350	COG1280	lysine exporter protein (LysE YggA)
AOT16_RS18355	COG2837	iron assimilation
AOT16_RS18365	COG0281	malic enzyme
AOT16_RS18410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AOT16_RS18410	COG0519	Catalyzes the synthesis of GMP from XMP
AOT16_RS18415	COG4399	Belongs to the UPF0754 family
AOT16_RS18420	COG2259	Doxx family
AOT16_RS18425	COG0586	Pfam SNARE associated Golgi protein
AOT16_RS18440	COG1192	Involved in chromosome partitioning
AOT16_RS18450	COG0271	Belongs to the BolA IbaG family
AOT16_RS18470	COG2267	carboxylic ester hydrolase activity
AOT16_RS18490	COG3321	synthase
AOT16_RS18490	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AOT16_RS18490	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AOT16_RS18490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AOT16_RS18495	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS18505	COG2197	response regulator
AOT16_RS18515	COG3916	Acyl-homoserine-lactone synthase
AOT16_RS18520	COG0477	Major facilitator Superfamily
AOT16_RS18525	COG1024	Enoyl-CoA hydratase
AOT16_RS18530	COG1024	Enoyl-CoA hydratase
AOT16_RS18535	COG1960	acyl-CoA dehydrogenase activity
AOT16_RS18560	COG1113	amino acid transport
AOT16_RS18565	COG1113	amino acid transport
AOT16_RS18570	COG0251	oxidation-reduction process
AOT16_RS18610	COG0564	pseudouridine synthase activity
AOT16_RS18675	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AOT16_RS18690	COG1802	Transcriptional regulator
AOT16_RS18695	COG1448	Aminotransferase
AOT16_RS18700	COG0277	FAD linked oxidase domain protein
AOT16_RS18710	COG2186	Transcriptional regulator
AOT16_RS18720	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AOT16_RS18725	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AOT16_RS18740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AOT16_RS18745	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AOT16_RS18750	COG1216	Glycosyl transferase, family 2
AOT16_RS18780	COG2089	acid synthase
AOT16_RS18795	COG1083	cytidylyl-transferase
AOT16_RS18800	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AOT16_RS18805	COG1086	Polysaccharide biosynthesis protein
AOT16_RS18810	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AOT16_RS18815	COG1596	polysaccharide export
AOT16_RS18840	COG0728	peptidoglycan biosynthetic process
AOT16_RS18845	COG3023	N-Acetylmuramoyl-L-alanine amidase
AOT16_RS18900	COG0546	phosphoglycolate phosphatase activity
AOT16_RS18905	COG1028	Short-chain dehydrogenase reductase Sdr
AOT16_RS18925	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT16_RS18930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AOT16_RS18935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AOT16_RS18940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AOT16_RS18945	COG1116	anion transmembrane transporter activity
AOT16_RS18950	COG1309	transcriptional regulator
AOT16_RS18955	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AOT16_RS18965	COG0196	riboflavin kinase activity
AOT16_RS18970	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AOT16_RS18980	COG1047	Peptidyl-prolyl cis-trans
AOT16_RS19020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AOT16_RS19025	COG0657	acetylesterase activity
AOT16_RS19045	COG0583	DNA-binding transcription factor activity
AOT16_RS19075	COG2951	lytic endotransglycosylase activity
AOT16_RS19080	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AOT16_RS19100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AOT16_RS19110	COG0671	phosphoesterase, PA-phosphatase related
AOT16_RS19115	COG0861	Integral membrane protein TerC family
AOT16_RS19125	COG0754	glutathionylspermidine amidase activity
AOT16_RS19135	COG0402	S-adenosylhomocysteine deaminase activity
AOT16_RS19150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AOT16_RS19155	COG1230	cation diffusion facilitator family transporter
AOT16_RS19170	COG0706	membrane insertase activity
AOT16_RS19480	COG2814	Major facilitator Superfamily
AOT16_RS19840	COG0488	(ABC) transporter
AOT16_RS20210	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AOT16_RS20255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)