locus-tag	class	description
FI878_RS00010	COG0592	DNA-directed DNA polymerase activity
FI878_RS00020	COG0187	DNA topoisomerase II activity
FI878_RS00030	COG0586	Pfam SNARE associated Golgi protein
FI878_RS00035	COG0488	(ABC) transporter
FI878_RS00060	COG0596	Alpha beta hydrolase
FI878_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FI878_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FI878_RS00110	COG0733	neurotransmitter:sodium symporter activity
FI878_RS00150	COG2233	PERMEase
FI878_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FI878_RS00200	COG2814	Major facilitator Superfamily
FI878_RS00205	COG0656	L-ascorbic acid biosynthetic process
FI878_RS00210	COG0583	DNA-binding transcription factor activity
FI878_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI878_RS00230	COG1064	alcohol dehydrogenase
FI878_RS00235	COG2818	Glycosylase
FI878_RS00250	COG1194	a g-specific adenine glycosylase
FI878_RS00275	COG2983	Belongs to the UPF0260 family
FI878_RS00280	COG2133	pyrroloquinoline quinone binding
FI878_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FI878_RS00290	COG2116	formate transmembrane transporter activity
FI878_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FI878_RS00315	COG1335	isochorismatase
FI878_RS00320	COG0385	Bile acid
FI878_RS00325	COG0534	Mate efflux family protein
FI878_RS00330	COG1683	Conserved Protein
FI878_RS00350	COG0625	glutathione transferase activity
FI878_RS00380	COG0523	cobalamin synthesis protein
FI878_RS00390	COG2188	Transcriptional regulator
FI878_RS00420	COG0010	Belongs to the arginase family
FI878_RS00435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FI878_RS00440	COG4372	Transposase
FI878_RS00475	COG3676	manually curated
FI878_RS00485	COG2814	Major facilitator Superfamily
FI878_RS00550	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FI878_RS00560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FI878_RS00565	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FI878_RS00665	COG0534	Mate efflux family protein
FI878_RS00670	COG0436	Aminotransferase
FI878_RS00675	COG2733	membrane
FI878_RS00690	COG2918	glutathione biosynthetic process
FI878_RS00700	COG3501	Rhs element vgr protein
FI878_RS00705	COG1388	LysM domain
FI878_RS00705	COG0791	NLP P60 protein
FI878_RS00720	COG3150	esterase
FI878_RS00730	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS00735	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FI878_RS00745	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FI878_RS00755	COG2233	PERMEase
FI878_RS00760	COG2351	hydroxyisourate hydrolase activity
FI878_RS00795	COG3706	GGDEF domain
FI878_RS00810	COG1393	Belongs to the ArsC family
FI878_RS00815	COG0708	Exodeoxyribonuclease III
FI878_RS00835	COG0189	ligase activity
FI878_RS00855	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FI878_RS00865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FI878_RS00880	COG4942	peptidase
FI878_RS00890	COG0508	dehydrogenase complex catalyzes the overall conversion of
FI878_RS00900	COG2119	membrane
FI878_RS00905	COG4774	siderophore transport
FI878_RS00910	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FI878_RS00910	COG0426	domain, Protein
FI878_RS00935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FI878_RS00955	COG1902	pentaerythritol trinitrate reductase activity
FI878_RS00960	COG1519	Transferase
FI878_RS00965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FI878_RS00970	COG0668	transmembrane transport
FI878_RS00980	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FI878_RS00985	COG1335	isochorismatase
FI878_RS00990	COG1522	sequence-specific DNA binding
FI878_RS00995	COG3328	transposase activity
FI878_RS01020	COG2205	protein histidine kinase activity
FI878_RS01020	COG2198	Histidine kinase
FI878_RS01020	COG0784	Response regulator, receiver
FI878_RS01025	COG3162	membrane
FI878_RS01030	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FI878_RS01040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FI878_RS01050	COG3706	GGDEF domain
FI878_RS01060	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FI878_RS01065	COG1309	transcriptional regulator
FI878_RS01085	COG0351	phosphomethylpyrimidine kinase
FI878_RS01085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FI878_RS01085	COG0352	thiamine-phosphate diphosphorylase activity
FI878_RS01095	COG2814	Major facilitator Superfamily
FI878_RS01110	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FI878_RS01120	COG1113	amino acid transport
FI878_RS01130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FI878_RS01135	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS01145	COG1335	isochorismatase
FI878_RS01185	COG2814	Major facilitator Superfamily
FI878_RS01190	COG0583	DNA-binding transcription factor activity
FI878_RS01210	COG0667	Aldo Keto reductase
FI878_RS01240	COG1733	regulation of RNA biosynthetic process
FI878_RS01245	COG2249	NAD(P)H dehydrogenase (quinone) activity
FI878_RS01310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FI878_RS01325	COG2329	Antibiotic biosynthesis monooxygenase
FI878_RS01355	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FI878_RS01385	COG0427	acetyl-CoA hydrolase
FI878_RS01400	COG0745	RESPONSE REGULATOR receiver
FI878_RS01410	COG0659	secondary active sulfate transmembrane transporter activity
FI878_RS01415	COG4221	oxidoreductase activity
FI878_RS01420	COG2873	o-acetylhomoserine
FI878_RS01425	COG0488	(ABC) transporter
FI878_RS01510	COG0833	amino acid
FI878_RS01555	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FI878_RS01560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FI878_RS01575	COG2226	methyltransferase
FI878_RS01625	COG0069	glutamate synthase activity
FI878_RS01625	COG0070	glutamate synthase
FI878_RS01625	COG0067	glutamate synthase
FI878_RS01630	COG0493	'glutamate synthase
FI878_RS01640	COG1704	LemA family
FI878_RS01645	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FI878_RS01665	COG3307	-O-antigen
FI878_RS01685	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FI878_RS01700	COG0194	GDP metabolic process
FI878_RS01750	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FI878_RS01770	COG5380	lipid catabolic process
FI878_RS01775	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FI878_RS01800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FI878_RS01805	COG0277	FAD linked oxidase domain protein
FI878_RS01815	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FI878_RS01820	COG2249	NAD(P)H dehydrogenase (quinone) activity
FI878_RS01835	COG1289	transmembrane transporter activity
FI878_RS01845	COG0628	permease
FI878_RS01850	COG1192	Involved in chromosome partitioning
FI878_RS01880	COG0833	amino acid
FI878_RS01885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FI878_RS01890	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FI878_RS01900	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS01940	COG0583	DNA-binding transcription factor activity
FI878_RS01985	COG0517	IMP dehydrogenase activity
FI878_RS01990	COG1983	PspC domain protein
FI878_RS02000	COG1960	acyl-CoA dehydrogenase activity
FI878_RS02015	COG0408	coproporphyrinogen oxidase activity
FI878_RS02035	COG0513	Belongs to the DEAD box helicase family
FI878_RS02045	COG1127	ABC transporter
FI878_RS02050	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FI878_RS02060	COG2854	intermembrane phospholipid transfer
FI878_RS02070	COG0598	Magnesium transport protein CorA
FI878_RS02080	COG0494	nUDIX hydrolase
FI878_RS02085	COG1040	competence protein
FI878_RS02090	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FI878_RS02110	COG1946	Acyl-CoA thioesterase
FI878_RS02115	COG1301	dicarboxylic acid transport
FI878_RS02130	COG1959	2 iron, 2 sulfur cluster binding
FI878_RS02135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FI878_RS02135	COG1017	nitric oxide dioxygenase activity
FI878_RS02140	COG0433	COG0433 Predicted ATPase
FI878_RS02145	COG0626	cystathionine gamma-synthase activity
FI878_RS02300	COG1960	acyl-CoA dehydrogenase activity
FI878_RS02305	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FI878_RS02335	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FI878_RS02340	COG0339	signal peptide processing
FI878_RS02345	COG0557	exoribonuclease II activity
FI878_RS02390	COG0179	Fumarylacetoacetate (FAA) hydrolase
FI878_RS02395	COG2169	Transcriptional regulator
FI878_RS02400	COG0697	spore germination
FI878_RS02405	COG1295	ribonuclease BN
FI878_RS02440	COG1702	phosphate starvation-inducible protein PhoH
FI878_RS02450	COG0741	lytic transglycosylase activity
FI878_RS02450	COG1196	nuclear chromosome segregation
FI878_RS02450	COG0739	heme binding
FI878_RS02480	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FI878_RS02485	COG1183	phosphatidylcholine synthase activity
FI878_RS02530	COG1960	acyl-CoA dehydrogenase activity
FI878_RS02535	COG1309	transcriptional regulator
FI878_RS02550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FI878_RS02555	COG1960	acyl-CoA dehydrogenase activity
FI878_RS02575	COG2969	positive regulation of protein catabolic process
FI878_RS02585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FI878_RS02600	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FI878_RS02605	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FI878_RS02625	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FI878_RS02635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FI878_RS02640	COG1408	metallophosphoesterase
FI878_RS02650	COG2199	diguanylate cyclase activity
FI878_RS02710	COG1607	acyl-coa hydrolase
FI878_RS02740	COG2350	Protein conserved in bacteria
FI878_RS02750	COG0613	PHP domain protein
FI878_RS02755	COG3781	membrane
FI878_RS02765	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FI878_RS02770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FI878_RS02780	COG1862	Preprotein translocase
FI878_RS02825	COG2205	protein histidine kinase activity
FI878_RS02830	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FI878_RS02850	COG0726	polysaccharide deacetylase
FI878_RS02855	COG0463	Glycosyl transferase, family 2
FI878_RS02860	COG0438	transferase activity, transferring glycosyl groups
FI878_RS02900	COG3676	manually curated
FI878_RS02935	COG0625	glutathione transferase activity
FI878_RS02940	COG0583	DNA-binding transcription factor activity
FI878_RS02945	COG1960	acyl-CoA dehydrogenase activity
FI878_RS02950	COG1960	acyl-CoA dehydrogenase activity
FI878_RS02960	COG2205	protein histidine kinase activity
FI878_RS02965	COG0745	RESPONSE REGULATOR receiver
FI878_RS02970	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FI878_RS02990	COG2096	Adenosyltransferase
FI878_RS03040	COG0285	dihydrofolate synthase activity
FI878_RS03060	COG0450	alkyl hydroperoxide reductase
FI878_RS03075	COG0477	Major facilitator Superfamily
FI878_RS03080	COG1272	protein, Hemolysin III
FI878_RS03115	COG0183	Belongs to the thiolase family
FI878_RS03120	COG2207	Transcriptional regulator
FI878_RS03140	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FI878_RS03160	COG0183	Belongs to the thiolase family
FI878_RS03170	COG2885	chlorophyll binding
FI878_RS03170	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FI878_RS03180	COG1690	Belongs to the RtcB family
FI878_RS03185	COG0833	amino acid
FI878_RS03195	COG2233	PERMEase
FI878_RS03225	COG2094	Belongs to the DNA glycosylase MPG family
FI878_RS03230	COG4772	TonB-dependent receptor
FI878_RS03235	COG1902	pentaerythritol trinitrate reductase activity
FI878_RS03240	COG0679	Auxin Efflux Carrier
FI878_RS03250	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FI878_RS03255	COG0354	folic acid binding
FI878_RS03265	COG3189	MarR family transcriptional regulator
FI878_RS03270	COG2824	Alkylphosphonate utilization operon protein PhnA
FI878_RS03275	COG3422	double-strand break repair
FI878_RS03315	COG0840	transmembrane signaling receptor activity
FI878_RS03335	COG5510	response to toxic substance
FI878_RS03345	COG2832	Protein of unknown function (DUF454)
FI878_RS03350	COG1376	ErfK ybiS ycfS ynhG family protein
FI878_RS03390	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FI878_RS03400	COG1289	transmembrane transporter activity
FI878_RS03405	COG2814	Major facilitator Superfamily
FI878_RS03425	COG1115	amino acid carrier protein
FI878_RS03430	COG1752	Esterase of the alpha-beta hydrolase superfamily
FI878_RS03435	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FI878_RS03440	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FI878_RS03470	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FI878_RS03480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FI878_RS03485	COG1077	Cell shape determining protein MreB Mrl
FI878_RS03490	COG1792	Involved in formation and maintenance of cell shape
FI878_RS03495	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FI878_RS03500	COG0424	maF-like protein
FI878_RS03505	COG1530	ribonuclease E activity
FI878_RS03515	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FI878_RS03525	COG0560	Phosphoserine phosphatase
FI878_RS03535	COG2249	NAD(P)H dehydrogenase (quinone) activity
FI878_RS03560	COG2207	Transcriptional regulator
FI878_RS03580	COG1113	amino acid transport
FI878_RS03585	COG2828	Protein conserved in bacteria
FI878_RS03590	COG0142	geranyltranstransferase activity
FI878_RS03595	COG2315	Protein conserved in bacteria
FI878_RS03610	COG1752	Esterase of the alpha-beta hydrolase superfamily
FI878_RS03630	COG2194	sulfuric ester hydrolase activity
FI878_RS03635	COG0745	RESPONSE REGULATOR receiver
FI878_RS03640	COG0642	Histidine kinase
FI878_RS03650	COG0004	ammonium transporteR
FI878_RS03655	COG0583	DNA-binding transcription factor activity
FI878_RS03675	COG0525	valine-tRNA ligase activity
FI878_RS03685	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS03695	COG0393	Putative heavy-metal-binding
FI878_RS03700	COG0393	Putative heavy-metal-binding
FI878_RS03705	COG1538	Outer membrane efflux protein
FI878_RS03715	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FI878_RS03720	COG0671	phosphoesterase, PA-phosphatase related
FI878_RS03750	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FI878_RS03765	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FI878_RS03765	COG1648	precorrin-2 dehydrogenase activity
FI878_RS03770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FI878_RS03775	COG1733	regulation of RNA biosynthetic process
FI878_RS03785	COG0531	amino acid
FI878_RS03800	COG0321	lipoyl(octanoyl) transferase activity
FI878_RS03805	COG2921	Belongs to the UPF0250 family
FI878_RS03845	COG2009	succinate dehydrogenase
FI878_RS03850	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FI878_RS03855	COG1053	succinate dehydrogenase
FI878_RS03860	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FI878_RS03885	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FI878_RS03905	COG2354	Protein conserved in bacteria
FI878_RS03910	COG2321	neutral zinc metallopeptidase
FI878_RS03940	COG2843	Capsule synthesis protein
FI878_RS03955	COG0589	response to stress
FI878_RS03975	COG0505	Belongs to the CarA family
FI878_RS04000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FI878_RS04005	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FI878_RS04055	COG0477	Major facilitator Superfamily
FI878_RS04065	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FI878_RS04080	COG1597	lipid kinase activity
FI878_RS04085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FI878_RS04110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI878_RS04115	COG0584	glycerophosphoryl diester phosphodiesterase
FI878_RS04135	COG0741	lytic transglycosylase activity
FI878_RS04155	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FI878_RS04170	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FI878_RS04195	COG0778	Nitroreductase
FI878_RS04210	COG1929	Belongs to the glycerate kinase type-1 family
FI878_RS04215	COG0243	molybdopterin cofactor binding
FI878_RS04220	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FI878_RS04225	COG3339	Conserved Protein
FI878_RS04235	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FI878_RS04250	COG1113	amino acid transport
FI878_RS04260	COG0019	diaminopimelate decarboxylase activity
FI878_RS04270	COG1280	lysine exporter protein (LysE YggA)
FI878_RS04275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FI878_RS04280	COG3676	manually curated
FI878_RS04320	COG0463	Glycosyl transferase, family 2
FI878_RS04340	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FI878_RS04375	COG4591	ABC-type transport system involved in lipoprotein release permease component
FI878_RS04380	COG1136	(ABC) transporter
FI878_RS04385	COG2333	competence protein COMEC
FI878_RS04385	COG0658	competence protein
FI878_RS04395	COG0616	signal peptide processing
FI878_RS04395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FI878_RS04400	COG0596	Alpha beta hydrolase
FI878_RS04405	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FI878_RS04415	COG0628	permease
FI878_RS04450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FI878_RS04470	COG0823	Involved in the tonB-independent uptake of proteins
FI878_RS04490	COG0824	Thioesterase
FI878_RS04495	COG1473	amidohydrolase
FI878_RS04515	COG0047	phosphoribosylformylglycinamidine synthase activity
FI878_RS04515	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FI878_RS04520	COG2814	Major facilitator Superfamily
FI878_RS04530	COG1024	Enoyl-CoA hydratase
FI878_RS04535	COG1051	belongs to the nudix hydrolase family
FI878_RS04535	COG1056	cytidyltransferase-related domain
FI878_RS04545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FI878_RS04560	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FI878_RS04575	COG4625	pathogenesis
FI878_RS04580	COG0583	DNA-binding transcription factor activity
FI878_RS04585	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FI878_RS04590	COG4208	sulfate ABC transporter
FI878_RS04595	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FI878_RS04605	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FI878_RS04610	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FI878_RS04615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FI878_RS04635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FI878_RS04650	COG0681	Belongs to the peptidase S26 family
FI878_RS04665	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FI878_RS04675	COG1381	Involved in DNA repair and RecF pathway recombination
FI878_RS04680	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FI878_RS04690	COG4221	oxidoreductase activity
FI878_RS04720	COG0436	Aminotransferase
FI878_RS04740	COG0556	nucleotide-excision repair
FI878_RS04795	COG2070	2-Nitropropane dioxygenase
FI878_RS04825	COG1215	transferase activity, transferring glycosyl groups
FI878_RS04840	COG0415	Belongs to the DNA photolyase family
FI878_RS04850	COG1252	NADH dehydrogenase
FI878_RS04855	COG1686	Belongs to the peptidase S11 family
FI878_RS04870	COG1187	pseudouridine synthase activity
FI878_RS04895	COG0477	Major facilitator Superfamily
FI878_RS04900	COG0583	DNA-binding transcription factor activity
FI878_RS04915	COG0612	Peptidase, M16
FI878_RS04940	COG0352	thiamine-phosphate diphosphorylase activity
FI878_RS04975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FI878_RS04990	COG1309	transcriptional regulator
FI878_RS05000	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FI878_RS05005	COG0076	glutamate decarboxylase activity
FI878_RS05015	COG1522	sequence-specific DNA binding
FI878_RS05020	COG3961	Belongs to the TPP enzyme family
FI878_RS05025	COG1113	amino acid transport
FI878_RS05030	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FI878_RS05035	COG0573	inorganic phosphate transmembrane transporter activity
FI878_RS05045	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FI878_RS05050	COG0616	signal peptide processing
FI878_RS05085	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FI878_RS05090	COG3676	manually curated
FI878_RS05095	COG1686	Belongs to the peptidase S11 family
FI878_RS05120	COG0583	DNA-binding transcription factor activity
FI878_RS05125	COG1067	ATP-dependent peptidase activity
FI878_RS05170	COG1966	Carbon starvation protein
FI878_RS05175	COG2879	small protein
FI878_RS05275	COG4626	Terminase
FI878_RS05275	COG1802	Transcriptional regulator
FI878_RS05290	COG3676	manually curated
FI878_RS05350	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
FI878_RS05430	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FI878_RS05430	COG2508	Transcriptional regulator
FI878_RS05450	COG1113	amino acid transport
FI878_RS05455	COG0583	DNA-binding transcription factor activity
FI878_RS05460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FI878_RS05465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FI878_RS05475	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS05480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FI878_RS05485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FI878_RS05485	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FI878_RS05520	COG2814	Major facilitator Superfamily
FI878_RS05525	COG4948	Mandelate Racemase Muconate Lactonizing
FI878_RS05535	COG1309	transcriptional regulator
FI878_RS05555	COG1741	Belongs to the pirin family
FI878_RS05565	COG2964	Protein conserved in bacteria
FI878_RS05580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FI878_RS05585	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FI878_RS05590	COG4605	iron ion homeostasis
FI878_RS05595	COG4604	ABC transporter, ATP-binding protein
FI878_RS05600	COG4607	ABC-type enterochelin transport system periplasmic component
FI878_RS05605	COG4774	siderophore transport
FI878_RS05615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FI878_RS05620	COG1021	2,3-dihydroxybenzoate-AMP ligase
FI878_RS05625	COG1535	isochorismatase
FI878_RS05625	COG3433	isochorismatase activity
FI878_RS05640	COG1132	(ABC) transporter
FI878_RS05650	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FI878_RS05660	COG1169	isochorismate synthase
FI878_RS05675	COG3739	integral membrane protein
FI878_RS05710	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FI878_RS05740	COG0308	aminopeptidase N
FI878_RS05745	COG0512	Glutamine amidotransferase of anthranilate synthase
FI878_RS05845	COG0305	Participates in initiation and elongation during chromosome replication
FI878_RS05905	COG5410	chromosome segregation
FI878_RS06030	COG0739	heme binding
FI878_RS06145	COG0174	glutamine synthetase
FI878_RS06155	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FI878_RS06190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FI878_RS06195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FI878_RS06200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FI878_RS06220	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FI878_RS06225	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FI878_RS06230	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FI878_RS06245	COG1960	acyl-CoA dehydrogenase activity
FI878_RS06250	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FI878_RS06255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FI878_RS06265	COG2223	nitrite transmembrane transporter activity
FI878_RS06275	COG0024	Methionine aminopeptidase
FI878_RS06280	COG0052	Belongs to the universal ribosomal protein uS2 family
FI878_RS06295	COG2207	Transcriptional regulator
FI878_RS06320	COG2951	lytic endotransglycosylase activity
FI878_RS06325	COG0772	Belongs to the SEDS family
FI878_RS06340	COG0842	Transport permease protein
FI878_RS06345	COG1131	(ABC) transporter
FI878_RS06390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FI878_RS06405	COG4215	(ABC) transporter
FI878_RS06410	COG4160	amino acid transport
FI878_RS06415	COG4598	ABC transporter
FI878_RS06425	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FI878_RS06435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI878_RS06450	COG1720	tRNA m6t6A37 methyltransferase activity
FI878_RS06470	COG0745	RESPONSE REGULATOR receiver
FI878_RS06475	COG0642	Histidine kinase
FI878_RS06485	COG0494	nUDIX hydrolase
FI878_RS06495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FI878_RS06500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FI878_RS06505	COG3139	Protein of unknown function (DUF1315)
FI878_RS06510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FI878_RS06515	COG1301	dicarboxylic acid transport
FI878_RS06520	COG1960	acyl-CoA dehydrogenase activity
FI878_RS06525	COG2819	hydrolase of the alpha beta superfamily
FI878_RS06535	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FI878_RS06545	COG2195	Cleaves the N-terminal amino acid of tripeptides
FI878_RS06550	COG1234	tRNA 3'-trailer cleavage
FI878_RS06585	COG2363	Small membrane protein
FI878_RS06605	COG0513	Belongs to the DEAD box helicase family
FI878_RS06615	COG0778	Nitroreductase
FI878_RS06645	COG1286	toxin biosynthetic process
FI878_RS06670	COG4783	chaperone-mediated protein folding
FI878_RS06675	COG1610	YqeY-like protein
FI878_RS06775	COG3111	PFAM Bacterial OB fold (BOF) protein
FI878_RS06855	COG2985	domain, Protein
FI878_RS06860	COG3676	manually curated
FI878_RS06870	COG2995	paraquat-inducible protein a
FI878_RS06875	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FI878_RS06875	COG3008	intermembrane lipid transfer
FI878_RS06885	COG1794	racemase activity, acting on amino acids and derivatives
FI878_RS06895	COG3676	manually curated
FI878_RS06925	COG1301	dicarboxylic acid transport
FI878_RS06935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI878_RS06940	COG2011	ABC-type metal ion transport system permease component
FI878_RS06945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FI878_RS06950	COG1464	Belongs to the NlpA lipoprotein family
FI878_RS06955	COG0151	Belongs to the GarS family
FI878_RS06960	COG0138	bifunctional purine biosynthesis protein purh
FI878_RS06965	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FI878_RS06995	COG2308	Evidence 4 Homologs of previously reported genes of
FI878_RS07005	COG1305	Transglutaminase-like
FI878_RS07015	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FI878_RS07020	COG0305	Participates in initiation and elongation during chromosome replication
FI878_RS07045	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FI878_RS07055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FI878_RS07060	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FI878_RS07085	COG0726	polysaccharide deacetylase
FI878_RS07085	COG1649	PFAM Uncharacterised BCR, COG1649
FI878_RS07090	COG1215	transferase activity, transferring glycosyl groups
FI878_RS07095	COG3658	cytochrome
FI878_RS07105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FI878_RS07120	COG0583	DNA-binding transcription factor activity
FI878_RS07140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FI878_RS07145	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FI878_RS07160	COG1960	acyl-CoA dehydrogenase activity
FI878_RS07165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FI878_RS07170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FI878_RS07195	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FI878_RS07200	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FI878_RS07210	COG2205	protein histidine kinase activity
FI878_RS07215	COG0745	RESPONSE REGULATOR receiver
FI878_RS07220	COG0174	glutamine synthetase
FI878_RS07225	COG3676	manually curated
FI878_RS07245	COG0729	surface antigen
FI878_RS07270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FI878_RS07275	COG2814	Major facilitator Superfamily
FI878_RS07290	COG0583	DNA-binding transcription factor activity
FI878_RS07305	COG3676	manually curated
FI878_RS07310	COG1187	pseudouridine synthase activity
FI878_RS07330	COG0802	atpase or kinase
FI878_RS07335	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FI878_RS07345	COG1923	regulation of RNA biosynthetic process
FI878_RS07350	COG0697	spore germination
FI878_RS07365	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FI878_RS07375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FI878_RS07380	COG0519	Catalyzes the synthesis of GMP from XMP
FI878_RS07380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FI878_RS07385	COG4302	ethanolamine ammonia-lyase activity
FI878_RS07390	COG4303	Ethanolamine ammonia lyase large subunit
FI878_RS07395	COG0531	amino acid
FI878_RS07415	COG1454	alcohol dehydrogenase
FI878_RS07420	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FI878_RS07430	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FI878_RS07450	COG0308	aminopeptidase N
FI878_RS07460	COG4221	oxidoreductase activity
FI878_RS07470	COG1605	Chorismate mutase
FI878_RS07485	COG1309	transcriptional regulator
FI878_RS07495	COG0668	transmembrane transport
FI878_RS07525	COG4773	Receptor
FI878_RS07545	COG0488	(ABC) transporter
FI878_RS07550	COG0589	response to stress
FI878_RS07575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FI878_RS07585	COG3135	benzoate transporter
FI878_RS07590	COG1522	sequence-specific DNA binding
FI878_RS07600	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FI878_RS07605	COG0583	DNA-binding transcription factor activity
FI878_RS07615	COG0183	Belongs to the thiolase family
FI878_RS07625	COG3676	manually curated
FI878_RS07650	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FI878_RS07660	COG0824	Thioesterase
FI878_RS07665	COG1454	alcohol dehydrogenase
FI878_RS07675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FI878_RS07695	COG0069	glutamate synthase activity
FI878_RS08025	COG2814	Major facilitator Superfamily
FI878_RS08040	COG0511	ligase activity, forming carbon-carbon bonds
FI878_RS08060	COG1116	anion transmembrane transporter activity
FI878_RS08060	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FI878_RS08065	COG0745	RESPONSE REGULATOR receiver
FI878_RS08075	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FI878_RS08075	COG2146	nitrite reductase [NAD(P)H] activity
FI878_RS08080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FI878_RS08085	COG0243	molybdopterin cofactor binding
FI878_RS08095	COG0243	molybdopterin cofactor binding
FI878_RS08100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FI878_RS08115	COG0315	cyclic pyranopterin monophosphate synthase activity
FI878_RS08115	COG0521	Mo-molybdopterin cofactor biosynthetic process
FI878_RS08120	COG0303	'Molybdopterin
FI878_RS08130	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI878_RS08135	COG0697	spore germination
FI878_RS08155	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FI878_RS08160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FI878_RS08215	COG3676	manually curated
FI878_RS08225	COG2204	response regulator
FI878_RS08230	COG3852	Histidine kinase
FI878_RS08250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FI878_RS08255	COG0575	Belongs to the CDS family
FI878_RS08290	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FI878_RS08305	COG2137	regulation of response to DNA damage stimulus
FI878_RS08315	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FI878_RS08320	COG1011	Hydrolase
FI878_RS08345	COG1522	sequence-specific DNA binding
FI878_RS08355	COG1113	amino acid transport
FI878_RS08370	COG0659	secondary active sulfate transmembrane transporter activity
FI878_RS08375	COG2135	peptidase activity
FI878_RS08390	COG3300	MHYT domain
FI878_RS08390	COG5001	Diguanylate cyclase
FI878_RS08410	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FI878_RS08410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FI878_RS08410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FI878_RS08415	COG1105	Belongs to the carbohydrate kinase PfkB family
FI878_RS08420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FI878_RS08420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FI878_RS08450	COG0024	Methionine aminopeptidase
FI878_RS08455	COG0583	DNA-binding transcription factor activity
FI878_RS08465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FI878_RS08470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FI878_RS08475	COG0516	GMP reductase activity
FI878_RS08475	COG0517	IMP dehydrogenase activity
FI878_RS08500	COG0552	protein localization to endoplasmic reticulum
FI878_RS08510	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FI878_RS08525	COG4890	Cyd operon protein YbgT
FI878_RS08530	COG1294	oxidase, subunit
FI878_RS08550	COG1585	Membrane protein implicated in regulation of membrane protease activity
FI878_RS08560	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FI878_RS08565	COG4774	siderophore transport
FI878_RS08570	COG3676	manually curated
FI878_RS08585	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FI878_RS08590	COG0569	domain protein
FI878_RS08595	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FI878_RS08625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FI878_RS08630	COG0542	response to heat
FI878_RS08655	COG0446	pyridine nucleotide-disulphide oxidoreductase
FI878_RS08655	COG1902	pentaerythritol trinitrate reductase activity
FI878_RS08700	COG2323	membrane
FI878_RS08705	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FI878_RS08715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FI878_RS08720	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FI878_RS08725	COG0183	Belongs to the thiolase family
FI878_RS08730	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FI878_RS08735	COG0596	Alpha beta hydrolase
FI878_RS08740	COG2271	Major facilitator Superfamily
FI878_RS08745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FI878_RS08750	COG3485	protocatechuate 3,4-dioxygenase
FI878_RS08755	COG3485	protocatechuate 3,4-dioxygenase
FI878_RS08760	COG0710	3-dehydroquinate dehydratase activity
FI878_RS08765	COG3420	alginic acid biosynthetic process
FI878_RS08770	COG3659	wide pore channel activity
FI878_RS08775	COG4993	Dehydrogenase
FI878_RS08785	COG2391	methyltransferase activity
FI878_RS08800	COG1414	Transcriptional regulator
FI878_RS08805	COG0583	DNA-binding transcription factor activity
FI878_RS08810	COG1960	acyl-CoA dehydrogenase activity
FI878_RS08835	COG2814	Major facilitator Superfamily
FI878_RS08845	COG0154	amidase activity
FI878_RS08865	COG4638	Rieske (2fe-2S)
FI878_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS08885	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FI878_RS08895	COG3733	amine oxidase
FI878_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS08915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FI878_RS08920	COG0183	Belongs to the thiolase family
FI878_RS08925	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FI878_RS08930	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FI878_RS08940	COG4829	muconolactone delta-isomerase
FI878_RS08945	COG4948	Mandelate Racemase Muconate Lactonizing
FI878_RS08950	COG0583	DNA-binding transcription factor activity
FI878_RS08960	COG2186	Transcriptional regulator
FI878_RS08980	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS09000	COG1960	acyl-CoA dehydrogenase activity
FI878_RS09005	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS09010	COG3829	transcription factor binding
FI878_RS09020	COG3162	membrane
FI878_RS09035	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS09050	COG0753	catalase activity
FI878_RS09070	COG1846	Transcriptional regulator
FI878_RS09075	COG0446	pyridine nucleotide-disulphide oxidoreductase
FI878_RS09075	COG1902	pentaerythritol trinitrate reductase activity
FI878_RS09085	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FI878_RS09115	COG1309	transcriptional regulator
FI878_RS09125	COG1335	isochorismatase
FI878_RS09130	COG0583	DNA-binding transcription factor activity
FI878_RS09140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FI878_RS09140	COG0475	glutathione-regulated potassium exporter activity
FI878_RS09150	COG1473	amidohydrolase
FI878_RS09160	COG2831	hemolysin activation secretion protein
FI878_RS09165	COG3210	domain, Protein
FI878_RS09195	COG2188	Transcriptional regulator
FI878_RS09210	COG0583	DNA-binding transcription factor activity
FI878_RS09240	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FI878_RS09260	COG1566	PFAM secretion protein HlyD family protein
FI878_RS09275	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS09280	COG0129	dihydroxy-acid dehydratase activity
FI878_RS09290	COG0583	DNA-binding transcription factor activity
FI878_RS09295	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FI878_RS09305	COG2084	Dehydrogenase
FI878_RS09310	COG2207	Transcriptional regulator
FI878_RS09325	COG1064	alcohol dehydrogenase
FI878_RS09340	COG1120	ATPase activity
FI878_RS09360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FI878_RS09465	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FI878_RS09515	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS09530	COG2207	Transcriptional regulator
FI878_RS09540	COG2205	protein histidine kinase activity
FI878_RS09545	COG0745	RESPONSE REGULATOR receiver
FI878_RS09550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FI878_RS09555	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FI878_RS09560	COG1538	Outer membrane efflux protein
FI878_RS09570	COG2072	flavoprotein involved in K transport
FI878_RS09590	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FI878_RS09610	COG3539	Fimbrial protein
FI878_RS09650	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FI878_RS09660	COG0753	catalase activity
FI878_RS09680	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FI878_RS09745	COG1535	isochorismatase
FI878_RS09745	COG3433	isochorismatase activity
FI878_RS09750	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS09755	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FI878_RS09760	COG4149	molybdate abc transporter
FI878_RS09765	COG0725	ABC transporter, periplasmic molybdate-binding protein
FI878_RS09775	COG4638	Rieske (2fe-2S)
FI878_RS09780	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FI878_RS09785	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FI878_RS09785	COG0543	2 iron, 2 sulfur cluster binding
FI878_RS09810	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS09825	COG2207	Transcriptional regulator
FI878_RS09835	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS09840	COG2610	gluconate transmembrane transporter activity
FI878_RS09850	COG0583	DNA-binding transcription factor activity
FI878_RS09860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FI878_RS09865	COG2031	fatty acid transporter
FI878_RS09870	COG0183	Belongs to the thiolase family
FI878_RS09875	COG0583	DNA-binding transcription factor activity
FI878_RS09880	COG0583	DNA-binding transcription factor activity
FI878_RS09895	COG1027	Aspartate ammonia-lyase
FI878_RS10010	COG2369	cell adhesion
FI878_RS10015	COG4383	Mu-like prophage protein gp29
FI878_RS10030	COG4373	Mu-like prophage FluMu protein gp28
FI878_RS10065	COG2932	Transcriptional regulator
FI878_RS10125	COG0776	regulation of translation
FI878_RS10170	COG3676	manually curated
FI878_RS10180	COG0477	Major facilitator Superfamily
FI878_RS10200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FI878_RS10205	COG4521	taurine ABC transporter
FI878_RS10220	COG2188	Transcriptional regulator
FI878_RS10230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FI878_RS10235	COG1733	regulation of RNA biosynthetic process
FI878_RS10240	COG2207	Transcriptional regulator
FI878_RS10240	COG3708	Transcriptional regulator
FI878_RS10255	COG0730	response to heat
FI878_RS10265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI878_RS10265	COG3453	Protein conserved in bacteria
FI878_RS10275	COG3781	membrane
FI878_RS10280	COG1063	alcohol dehydrogenase
FI878_RS10290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FI878_RS10295	COG0508	dehydrogenase complex catalyzes the overall conversion of
FI878_RS10300	COG0022	dehydrogenase e1 component
FI878_RS10305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FI878_RS10310	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FI878_RS10325	COG3706	GGDEF domain
FI878_RS10340	COG0133	tryptophan synthase activity
FI878_RS10350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FI878_RS10385	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FI878_RS10410	COG2226	methyltransferase
FI878_RS10465	COG0842	Transport permease protein
FI878_RS10470	COG0842	Transport permease protein
FI878_RS10475	COG1131	(ABC) transporter
FI878_RS10490	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FI878_RS10495	COG4773	Receptor
FI878_RS10515	COG0730	response to heat
FI878_RS10520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FI878_RS10540	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FI878_RS10595	COG4264	IucA IucC family
FI878_RS10600	COG4264	IucA IucC family
FI878_RS10620	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FI878_RS10635	COG1960	acyl-CoA dehydrogenase activity
FI878_RS10640	COG1960	acyl-CoA dehydrogenase activity
FI878_RS10645	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FI878_RS10650	COG2207	Transcriptional regulator
FI878_RS10655	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FI878_RS10660	COG0776	regulation of translation
FI878_RS10685	COG0822	iron-sulfur transferase activity
FI878_RS10690	COG0316	Belongs to the HesB IscA family
FI878_RS10720	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FI878_RS10740	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FI878_RS10745	COG0702	epimerase
FI878_RS10780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FI878_RS10790	COG0339	signal peptide processing
FI878_RS10840	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FI878_RS10910	COG0739	heme binding
FI878_RS10910	COG0741	lytic transglycosylase activity
FI878_RS10910	COG1196	nuclear chromosome segregation
FI878_RS10970	COG4695	Portal protein
FI878_RS11065	COG0305	Participates in initiation and elongation during chromosome replication
FI878_RS11135	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FI878_RS11165	COG0776	regulation of translation
FI878_RS11230	COG0084	hydrolase, TatD family'
FI878_RS11250	COG1663	tetraacyldisaccharide 4'-kinase activity
FI878_RS11255	COG1132	(ABC) transporter
FI878_RS11265	COG0811	peptide transport
FI878_RS11270	COG1475	DNA binding
FI878_RS11275	COG1192	Involved in chromosome partitioning
FI878_RS11285	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FI878_RS11300	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FI878_RS11305	COG0191	fructose-bisphosphate aldolase activity
FI878_RS11325	COG0424	maF-like protein
FI878_RS11330	COG2850	peptidyl-arginine hydroxylation
FI878_RS11340	COG0640	Transcriptional regulator
FI878_RS11350	COG3619	membrane
FI878_RS11355	COG3122	Protein conserved in bacteria
FI878_RS11360	COG3676	manually curated
FI878_RS11365	COG1132	(ABC) transporter
FI878_RS11385	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FI878_RS11390	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FI878_RS11400	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FI878_RS11400	COG0506	proline dehydrogenase activity
FI878_RS11400	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FI878_RS11405	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FI878_RS11420	COG3698	Phosphodiester glycosidase
FI878_RS11430	COG2353	YceI-like domain
FI878_RS11440	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FI878_RS11485	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FI878_RS11485	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FI878_RS11510	COG3539	Fimbrial protein
FI878_RS11515	COG3121	Chaperone
FI878_RS11540	COG0697	spore germination
FI878_RS11550	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FI878_RS11560	COG0583	DNA-binding transcription factor activity
FI878_RS11580	COG1309	transcriptional regulator
FI878_RS11595	COG1522	sequence-specific DNA binding
FI878_RS11605	COG1126	abc transporter atp-binding protein
FI878_RS11610	COG0765	amino acid transport
FI878_RS11615	COG0765	amino acid transport
FI878_RS11645	COG1464	Belongs to the NlpA lipoprotein family
FI878_RS11655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FI878_RS11660	COG2011	ABC-type metal ion transport system permease component
FI878_RS11665	COG0012	GTP binding
FI878_RS11690	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FI878_RS11730	COG0386	Belongs to the glutathione peroxidase family
FI878_RS11740	COG0436	Aminotransferase
FI878_RS11780	COG3634	alkyl hydroperoxide reductase activity
FI878_RS11795	COG0583	DNA-binding transcription factor activity
FI878_RS11800	COG0798	PFAM Bile acid sodium symporter
FI878_RS11805	COG0640	Transcriptional regulator
FI878_RS11820	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FI878_RS11830	COG0583	DNA-binding transcription factor activity
FI878_RS11840	COG1953	Uracil, thiamine, allantoin
FI878_RS11850	COG2175	clavaminate synthase activity
FI878_RS11855	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FI878_RS11860	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FI878_RS11865	COG4521	taurine ABC transporter
FI878_RS11875	COG0477	Major facilitator Superfamily
FI878_RS11895	COG1271	oxidase subunit
FI878_RS11900	COG1294	oxidase, subunit
FI878_RS11910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI878_RS11950	COG3052	prosthetic group binding
FI878_RS11955	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FI878_RS11965	COG2814	Major facilitator Superfamily
FI878_RS11985	COG1346	cytolysis
FI878_RS11995	COG0583	DNA-binding transcription factor activity
FI878_RS12000	COG0625	glutathione transferase activity
FI878_RS12005	COG0625	glutathione transferase activity
FI878_RS12010	COG0583	DNA-binding transcription factor activity
FI878_RS12025	COG1045	serine acetyltransferase
FI878_RS12030	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FI878_RS12035	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FI878_RS12045	COG1280	lysine exporter protein (LysE YggA)
FI878_RS12060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FI878_RS12065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FI878_RS12070	COG1126	abc transporter atp-binding protein
FI878_RS12075	COG0765	amino acid transport
FI878_RS12080	COG0765	amino acid transport
FI878_RS12100	COG0784	Response regulator, receiver
FI878_RS12100	COG2205	protein histidine kinase activity
FI878_RS12120	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FI878_RS12140	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS12190	COG0583	DNA-binding transcription factor activity
FI878_RS12210	COG0318	PFAM AMP-dependent synthetase and ligase
FI878_RS12215	COG1309	transcriptional regulator
FI878_RS12220	COG1960	acyl-CoA dehydrogenase activity
FI878_RS12225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FI878_RS12230	COG1024	Enoyl-CoA hydratase
FI878_RS12235	COG4770	biotin carboxylase activity
FI878_RS12245	COG0583	DNA-binding transcription factor activity
FI878_RS12260	COG1960	acyl-CoA dehydrogenase activity
FI878_RS12270	COG2814	Major facilitator Superfamily
FI878_RS12280	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FI878_RS12285	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FI878_RS12290	COG2814	Major facilitator Superfamily
FI878_RS12295	COG1960	acyl-CoA dehydrogenase activity
FI878_RS12300	COG1024	Enoyl-CoA hydratase
FI878_RS12305	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS12310	COG1250	3-hydroxyacyl-CoA dehydrogenase
FI878_RS12315	COG0183	Belongs to the thiolase family
FI878_RS12325	COG2814	Major facilitator Superfamily
FI878_RS12335	COG1024	Enoyl-CoA hydratase
FI878_RS12350	COG1960	acyl-CoA dehydrogenase activity
FI878_RS12355	COG2814	Major facilitator Superfamily
FI878_RS12360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FI878_RS12365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FI878_RS12380	COG3842	ATPase activity
FI878_RS12385	COG1840	ABC-type Fe3 transport system, periplasmic component
FI878_RS12395	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FI878_RS12400	COG1414	Transcriptional regulator
FI878_RS12410	COG0583	DNA-binding transcription factor activity
FI878_RS12415	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FI878_RS12420	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS12430	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FI878_RS12440	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS12445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FI878_RS12450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FI878_RS12455	COG2267	carboxylic ester hydrolase activity
FI878_RS12475	COG3038	cytochrome b561
FI878_RS12480	COG0753	catalase activity
FI878_RS12515	COG2050	protein possibly involved in aromatic compounds catabolism
FI878_RS12525	COG3327	negative regulation of DNA-templated transcription, initiation
FI878_RS12530	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FI878_RS12535	COG0183	Belongs to the thiolase family
FI878_RS12540	COG1250	3-hydroxyacyl-CoA dehydrogenase
FI878_RS12545	COG1024	Enoyl-CoA hydratase
FI878_RS12550	COG1024	Enoyl-CoA hydratase
FI878_RS12555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FI878_RS12560	COG2151	metal-sulfur cluster biosynthetic enzyme
FI878_RS12565	COG3396	Phenylacetate-CoA oxygenase
FI878_RS12570	COG3460	Phenylacetate-CoA oxygenase
FI878_RS12575	COG3396	Phenylacetate-CoA oxygenase
FI878_RS12580	COG2030	dehydratase
FI878_RS12580	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS12585	COG1760	l-serine dehydratase
FI878_RS12590	COG0531	amino acid
FI878_RS12595	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS12610	COG0446	pyridine nucleotide-disulphide oxidoreductase
FI878_RS12620	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FI878_RS12640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FI878_RS12650	COG0789	Transcriptional regulator
FI878_RS12675	COG0038	chloride channel
FI878_RS12680	COG4770	biotin carboxylase activity
FI878_RS12700	COG1914	H( )-stimulated, divalent metal cation uptake system
FI878_RS12705	COG0583	DNA-binding transcription factor activity
FI878_RS12720	COG3209	COG3209 Rhs family protein
FI878_RS12725	COG3501	Rhs element vgr protein
FI878_RS12755	COG1250	3-hydroxyacyl-CoA dehydrogenase
FI878_RS12775	COG2814	Major facilitator Superfamily
FI878_RS12785	COG1560	Kdo2-lipid A biosynthetic process
FI878_RS12795	COG5006	permease, DMT superfamily
FI878_RS12800	COG1522	sequence-specific DNA binding
FI878_RS12815	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FI878_RS12825	COG4122	O-methyltransferase activity
FI878_RS12855	COG1538	Outer membrane efflux protein
FI878_RS12865	COG1137	ATPase activity
FI878_RS12870	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FI878_RS12880	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FI878_RS12885	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FI878_RS12885	COG0517	IMP dehydrogenase activity
FI878_RS12925	COG2814	Major facilitator Superfamily
FI878_RS12955	COG3676	manually curated
FI878_RS12970	COG1278	Cold shock
FI878_RS12975	COG1280	lysine exporter protein (LysE YggA)
FI878_RS13010	COG1570	exodeoxyribonuclease VII activity
FI878_RS13060	COG0583	DNA-binding transcription factor activity
FI878_RS13065	COG4638	Rieske (2fe-2S)
FI878_RS13070	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FI878_RS13075	COG0633	Ferredoxin
FI878_RS13075	COG0543	2 iron, 2 sulfur cluster binding
FI878_RS13080	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS13085	COG3135	benzoate transporter
FI878_RS13090	COG2814	Major facilitator Superfamily
FI878_RS13105	COG1643	Atp-dependent helicase
FI878_RS13110	COG0450	alkyl hydroperoxide reductase
FI878_RS13120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FI878_RS13130	COG3634	alkyl hydroperoxide reductase activity
FI878_RS13150	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FI878_RS13155	COG0625	glutathione transferase activity
FI878_RS13165	COG2885	chlorophyll binding
FI878_RS13200	COG0542	response to heat
FI878_RS13215	COG1765	OsmC-like protein
FI878_RS13230	COG0667	Aldo Keto reductase
FI878_RS13245	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FI878_RS13255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FI878_RS13265	COG0527	aspartate kinase activity
FI878_RS13275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FI878_RS13285	COG3038	cytochrome b561
FI878_RS13290	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FI878_RS13295	COG2252	PERMEase
FI878_RS13305	COG2072	flavoprotein involved in K transport
FI878_RS13320	COG1741	Belongs to the pirin family
FI878_RS13325	COG1309	transcriptional regulator
FI878_RS13335	COG0300	oxidoreductase activity
FI878_RS13420	COG0446	pyridine nucleotide-disulphide oxidoreductase
FI878_RS13420	COG1902	pentaerythritol trinitrate reductase activity
FI878_RS13430	COG2203	Gaf domain
FI878_RS13430	COG4251	negative regulation of phosphorylation
FI878_RS13430	COG3706	GGDEF domain
FI878_RS13430	COG5001	Diguanylate cyclase
FI878_RS13440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FI878_RS13460	COG4172	Belongs to the ABC transporter superfamily
FI878_RS13465	COG4239	(ABC) transporter, permease
FI878_RS13470	COG4174	ABC transporter (Permease)
FI878_RS13480	COG0741	lytic transglycosylase activity
FI878_RS13480	COG1388	LysM domain
FI878_RS13480	COG1388	LysM domain
FI878_RS13480	COG0741	lytic transglycosylase activity
FI878_RS13485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FI878_RS13525	COG0583	DNA-binding transcription factor activity
FI878_RS13530	COG1279	arginine transmembrane transporter activity
FI878_RS13550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FI878_RS13555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FI878_RS13560	COG0006	proline dipeptidase activity
FI878_RS13595	COG2194	sulfuric ester hydrolase activity
FI878_RS13640	COG0739	heme binding
FI878_RS13965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FI878_RS13995	COG3384	dioxygenase
FI878_RS14005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FI878_RS14010	COG2878	Part of a membrane complex involved in electron transport
FI878_RS14015	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FI878_RS14040	COG0768	penicillin binding
FI878_RS14045	COG0742	ribosomal rna small subunit methyltransferase
FI878_RS14060	COG0830	nickel cation binding
FI878_RS14070	COG0804	urea catabolic process
FI878_RS14110	COG1253	flavin adenine dinucleotide binding
FI878_RS14115	COG2851	Citrate transporter
FI878_RS14165	COG1773	rubredoxin
FI878_RS14170	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FI878_RS14180	COG0583	DNA-binding transcription factor activity
FI878_RS14205	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FI878_RS14210	COG4181	ATPase activity
FI878_RS14255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FI878_RS14275	COG0306	phosphate transporter
FI878_RS14285	COG3958	Transketolase
FI878_RS14290	COG3959	Transketolase, thiamine diphosphate binding domain
FI878_RS14295	COG2271	Major facilitator Superfamily
FI878_RS14300	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS14305	COG0583	DNA-binding transcription factor activity
FI878_RS14320	COG2223	nitrite transmembrane transporter activity
FI878_RS14325	COG2207	Transcriptional regulator
FI878_RS14330	COG2066	Belongs to the glutaminase family
FI878_RS14335	COG0242	peptide deformylase activity
FI878_RS14340	COG0477	Major facilitator Superfamily
FI878_RS14350	COG0028	Belongs to the TPP enzyme family
FI878_RS14365	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS14370	COG2267	carboxylic ester hydrolase activity
FI878_RS14380	COG2271	Major facilitator Superfamily
FI878_RS14385	COG0446	pyridine nucleotide-disulphide oxidoreductase
FI878_RS14415	COG1414	Transcriptional regulator
FI878_RS14430	COG1024	Enoyl-CoA hydratase
FI878_RS14440	COG1215	transferase activity, transferring glycosyl groups
FI878_RS14445	COG0726	polysaccharide deacetylase
FI878_RS14445	COG1649	PFAM Uncharacterised BCR, COG1649
FI878_RS14455	COG4681	YaeQ
FI878_RS14465	COG0523	cobalamin synthesis protein
FI878_RS14475	COG1607	acyl-coa hydrolase
FI878_RS14485	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FI878_RS14490	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FI878_RS14495	COG1309	transcriptional regulator
FI878_RS14520	COG2040	homocysteine
FI878_RS14525	COG0531	amino acid
FI878_RS14560	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FI878_RS14565	COG0477	Major facilitator Superfamily
FI878_RS14685	COG0592	DNA-directed DNA polymerase activity
FI878_RS14730	COG2026	Addiction module toxin, RelE StbE family
FI878_RS14925	COG1484	DNA-dependent DNA replication
FI878_RS15015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FI878_RS15085	COG0405	Gamma-glutamyltransferase
FI878_RS15090	COG2814	Major facilitator Superfamily
FI878_RS15100	COG2050	protein possibly involved in aromatic compounds catabolism
FI878_RS15115	COG1090	epimerase
FI878_RS15135	COG0420	3'-5' exonuclease activity
FI878_RS15160	COG0735	belongs to the Fur family
FI878_RS15165	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FI878_RS15185	COG0121	glutamine amidotransferase
FI878_RS15200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FI878_RS15210	COG0210	DNA helicase
FI878_RS15215	COG2885	chlorophyll binding
FI878_RS15220	COG0204	Acyl-transferase
FI878_RS15235	COG2894	cell division
FI878_RS15255	COG1280	lysine exporter protein (LysE YggA)
FI878_RS15260	COG1674	ftsk spoiiie
FI878_RS15260	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FI878_RS15265	COG0492	ferredoxin-NADP+ reductase activity
FI878_RS15270	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FI878_RS15280	COG0456	acetyltransferase
FI878_RS15340	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FI878_RS15340	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FI878_RS15360	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS15380	COG0473	3-isopropylmalate dehydrogenase activity
FI878_RS15385	COG0583	DNA-binding transcription factor activity
FI878_RS15405	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FI878_RS15430	COG0564	pseudouridine synthase activity
FI878_RS15440	COG0358	DNA primase activity
FI878_RS15455	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FI878_RS15480	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FI878_RS15510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FI878_RS15520	COG0351	phosphomethylpyrimidine kinase
FI878_RS15520	COG0352	thiamine-phosphate diphosphorylase activity
FI878_RS15520	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FI878_RS15525	COG1652	LysM domain
FI878_RS15550	COG1399	metal-binding, possibly nucleic acid-binding protein
FI878_RS15555	COG3101	peptidyl-lysine hydroxylation
FI878_RS15560	COG0009	L-threonylcarbamoyladenylate synthase
FI878_RS15565	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FI878_RS15570	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FI878_RS15585	COG4106	trans-aconitate 2-methyltransferase activity
FI878_RS15600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FI878_RS15600	COG2226	methyltransferase
FI878_RS15600	COG0596	Alpha beta hydrolase
FI878_RS15605	COG1877	trehalose-phosphatase activity
FI878_RS15610	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FI878_RS15615	COG2223	nitrite transmembrane transporter activity
FI878_RS15635	COG1196	nuclear chromosome segregation
FI878_RS15645	COG0730	response to heat
FI878_RS15660	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FI878_RS15670	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FI878_RS15720	COG0489	protein tyrosine kinase activity
FI878_RS15730	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FI878_RS15730	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FI878_RS15760	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FI878_RS15765	COG2081	HI0933 family
FI878_RS15775	COG0668	transmembrane transport
FI878_RS15795	COG0583	DNA-binding transcription factor activity
FI878_RS15815	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FI878_RS15820	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FI878_RS15850	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FI878_RS15885	COG2205	protein histidine kinase activity
FI878_RS15890	COG0745	RESPONSE REGULATOR receiver
FI878_RS15910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FI878_RS15920	COG2205	protein histidine kinase activity
FI878_RS15975	COG3676	manually curated
FI878_RS16005	COG4993	Dehydrogenase
FI878_RS16025	COG0384	phenazine biosynthesis protein PhzF
FI878_RS16045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FI878_RS16060	COG0583	DNA-binding transcription factor activity
FI878_RS16080	COG1473	amidohydrolase
FI878_RS16090	COG0583	DNA-binding transcription factor activity
FI878_RS16105	COG0583	DNA-binding transcription factor activity
FI878_RS16110	COG1053	succinate dehydrogenase
FI878_RS16120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FI878_RS16125	COG2814	Major facilitator Superfamily
FI878_RS16130	COG1960	acyl-CoA dehydrogenase activity
FI878_RS16135	COG0583	DNA-binding transcription factor activity
FI878_RS16140	COG1063	alcohol dehydrogenase
FI878_RS16170	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FI878_RS16175	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FI878_RS16180	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FI878_RS16195	COG3667	copper resistance
FI878_RS16200	COG2132	Multicopper oxidase
FI878_RS16210	COG0561	phosphatase activity
FI878_RS16215	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FI878_RS16240	COG1214	PFAM Peptidase M22, glycoprotease
FI878_RS16290	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FI878_RS16300	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FI878_RS16305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FI878_RS16310	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FI878_RS16370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FI878_RS16380	COG1846	Transcriptional regulator
FI878_RS16385	COG1764	response to oxidative stress
FI878_RS16425	COG0037	tRNA processing
FI878_RS16435	COG0248	Ppx GppA phosphatase
FI878_RS16465	COG0072	phenylalanine-tRNA ligase activity
FI878_RS16505	COG1238	metal cluster binding
FI878_RS16510	COG0625	glutathione transferase activity
FI878_RS16525	COG0318	PFAM AMP-dependent synthetase and ligase
FI878_RS16530	COG3028	Belongs to the UPF0307 family
FI878_RS16535	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FI878_RS16555	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FI878_RS16560	COG0617	tRNA 3'-terminal CCA addition
FI878_RS16565	COG1555	photosystem II stabilization
FI878_RS16570	COG3956	TIGRFAM MazG family protein
FI878_RS16580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FI878_RS16600	COG0784	Response regulator, receiver
FI878_RS16600	COG2205	protein histidine kinase activity
FI878_RS16600	COG5002	protein histidine kinase activity
FI878_RS16605	COG1024	Enoyl-CoA hydratase
FI878_RS16610	COG2084	Dehydrogenase
FI878_RS16615	COG3622	Belongs to the hyi family
FI878_RS16645	COG3676	manually curated
FI878_RS16650	COG0697	spore germination
FI878_RS16660	COG2814	Major facilitator Superfamily
FI878_RS16665	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FI878_RS16675	COG0583	DNA-binding transcription factor activity
FI878_RS16685	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FI878_RS16700	COG0084	hydrolase, TatD family'
FI878_RS16715	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FI878_RS16735	COG3676	manually curated
FI878_RS16750	COG0440	acetolactate synthase activity
FI878_RS16755	COG0028	Belongs to the TPP enzyme family
FI878_RS16780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FI878_RS16785	COG1136	(ABC) transporter
FI878_RS16785	COG0577	efflux transmembrane transporter activity
FI878_RS16790	COG1538	Outer membrane efflux protein
FI878_RS16805	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FI878_RS16810	COG1162	GTPase activity
FI878_RS16820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FI878_RS16840	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FI878_RS16845	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS16885	COG2986	histidine ammonia-lyase
FI878_RS16900	COG0318	PFAM AMP-dependent synthetase and ligase
FI878_RS16910	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FI878_RS16955	COG1426	Protein conserved in bacteria
FI878_RS16990	COG0793	Belongs to the peptidase S41A family
FI878_RS17005	COG2267	carboxylic ester hydrolase activity
FI878_RS17015	COG1012	belongs to the aldehyde dehydrogenase family
FI878_RS17020	COG3265	gluconokinase activity
FI878_RS17030	COG0800	Aldolase
FI878_RS17045	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FI878_RS17050	COG0280	phosphate acetyltransferase
FI878_RS17050	COG0857	belongs to the CobB CobQ family
FI878_RS17055	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FI878_RS17055	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FI878_RS17075	COG0740	serine-type endopeptidase activity
FI878_RS17085	COG4774	siderophore transport
FI878_RS17095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FI878_RS17105	COG2813	Specifically methylates the guanine in position
FI878_RS17105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FI878_RS17205	COG0788	formyltetrahydrofolate deformylase activity
FI878_RS17230	COG4651	solute:proton antiporter activity
FI878_RS17230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FI878_RS17250	COG0724	RNA recognition motif
FI878_RS17255	COG0210	DNA helicase
FI878_RS17280	COG1733	regulation of RNA biosynthetic process
FI878_RS17290	COG2900	Belongs to the SlyX family
FI878_RS17300	COG1280	lysine exporter protein (LysE YggA)
FI878_RS17305	COG1560	Kdo2-lipid A biosynthetic process
FI878_RS17315	COG1301	dicarboxylic acid transport
FI878_RS17370	COG0473	3-isopropylmalate dehydrogenase activity
FI878_RS17435	COG0583	DNA-binding transcription factor activity
FI878_RS17445	COG0625	glutathione transferase activity
FI878_RS17450	COG2378	regulation of single-species biofilm formation
FI878_RS17455	COG0546	phosphoglycolate phosphatase activity
FI878_RS17465	COG1530	ribonuclease E activity
FI878_RS17470	COG0318	PFAM AMP-dependent synthetase and ligase
FI878_RS17485	COG0583	DNA-binding transcription factor activity
FI878_RS17490	COG4221	oxidoreductase activity
FI878_RS17495	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FI878_RS17505	COG0534	Mate efflux family protein
FI878_RS17520	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FI878_RS17560	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FI878_RS17565	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FI878_RS17580	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FI878_RS17590	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FI878_RS17590	COG0644	oxidoreductase
FI878_RS17595	COG0425	Belongs to the sulfur carrier protein TusA family
FI878_RS17600	COG4535	Mg2 and Co2 transporter CorC
FI878_RS17610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FI878_RS17630	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FI878_RS17635	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FI878_RS17635	COG0475	glutathione-regulated potassium exporter activity
FI878_RS17640	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FI878_RS17650	COG0484	heat shock protein binding
FI878_RS17655	COG0789	Transcriptional regulator
FI878_RS17660	COG0598	Magnesium transport protein CorA
FI878_RS17680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FI878_RS17685	COG1074	ATP-dependent DNA helicase activity
FI878_RS17690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FI878_RS17710	COG2226	methyltransferase
FI878_RS17725	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FI878_RS17730	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FI878_RS17745	COG2111	Na H antiporter
FI878_RS17745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FI878_RS17750	COG1006	Multisubunit Na H antiporter MnhC subunit
FI878_RS17755	COG0651	ATP synthesis coupled electron transport
FI878_RS17765	COG2212	antiporter activity
FI878_RS17785	COG0195	Participates in both transcription termination and antitermination
FI878_RS17835	COG0237	dephospho-CoA kinase activity
FI878_RS17845	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FI878_RS17860	COG0497	DNA recombination
FI878_RS17870	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FI878_RS17900	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FI878_RS17900	COG2169	Transcriptional regulator
FI878_RS17905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FI878_RS17970	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FI878_RS17985	COG0326	Molecular chaperone. Has ATPase activity
FI878_RS18000	COG2056	Na+-H+ antiporter family
FI878_RS18005	COG0596	Alpha beta hydrolase
FI878_RS18110	COG0546	phosphoglycolate phosphatase activity
FI878_RS18115	COG1716	ATPase activity
FI878_RS18160	COG0181	hydroxymethylbilane synthase activity
FI878_RS18170	COG3275	phosphorelay sensor kinase activity
FI878_RS18190	COG1538	Outer membrane efflux protein
FI878_RS18195	COG0697	spore germination
FI878_RS18220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FI878_RS18225	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FI878_RS18230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FI878_RS18235	COG0772	Belongs to the SEDS family
FI878_RS18260	COG4974	Belongs to the 'phage' integrase family
FI878_RS18265	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FI878_RS18275	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FI878_RS18285	COG2197	response regulator
FI878_RS18300	COG0793	Belongs to the peptidase S41A family
FI878_RS18305	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FI878_RS18310	COG0795	lipopolysaccharide-transporting ATPase activity
FI878_RS18350	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FI878_RS18350	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FI878_RS18360	COG0004	ammonium transporteR
FI878_RS18365	COG0347	Belongs to the P(II) protein family
FI878_RS18375	COG0606	chelatase, subunit chli
FI878_RS18445	COG1061	Type III restriction enzyme res subunit
FI878_RS18460	COG0659	secondary active sulfate transmembrane transporter activity
FI878_RS18465	COG0589	response to stress
FI878_RS18490	COG3676	manually curated
FI878_RS18505	COG0606	chelatase, subunit chli
FI878_RS18510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FI878_RS18520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FI878_RS18535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FI878_RS18550	COG0318	PFAM AMP-dependent synthetase and ligase
FI878_RS18560	COG0477	Major facilitator Superfamily
FI878_RS18565	COG2860	membrane
FI878_RS18575	COG1253	flavin adenine dinucleotide binding
FI878_RS18595	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FI878_RS18630	COG0655	NAD(P)H dehydrogenase (quinone) activity
FI878_RS18640	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FI878_RS18710	COG0758	DNA mediated transformation
FI878_RS18720	COG0697	spore germination
FI878_RS18725	COG1309	transcriptional regulator
FI878_RS18740	COG0386	Belongs to the glutathione peroxidase family
FI878_RS18805	COG1121	(ABC) transporter
FI878_RS18810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FI878_RS18815	COG1280	lysine exporter protein (LysE YggA)
FI878_RS18820	COG2837	iron assimilation
FI878_RS18825	COG0281	malic enzyme
FI878_RS18870	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FI878_RS18870	COG0519	Catalyzes the synthesis of GMP from XMP
FI878_RS18875	COG4399	Belongs to the UPF0754 family
FI878_RS18880	COG2259	Doxx family
FI878_RS18885	COG0586	Pfam SNARE associated Golgi protein
FI878_RS18900	COG1192	Involved in chromosome partitioning
FI878_RS18910	COG0271	Belongs to the BolA IbaG family
FI878_RS18930	COG2267	carboxylic ester hydrolase activity
FI878_RS18945	COG1024	Enoyl-CoA hydratase
FI878_RS18950	COG1024	Enoyl-CoA hydratase
FI878_RS18955	COG1960	acyl-CoA dehydrogenase activity
FI878_RS18960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FI878_RS18980	COG1113	amino acid transport
FI878_RS18985	COG0251	oxidation-reduction process
FI878_RS19025	COG0564	pseudouridine synthase activity
FI878_RS19055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FI878_RS19070	COG1802	Transcriptional regulator
FI878_RS19080	COG1448	Aminotransferase
FI878_RS19085	COG0277	FAD linked oxidase domain protein
FI878_RS19095	COG2186	Transcriptional regulator
FI878_RS19105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FI878_RS19115	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FI878_RS19130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FI878_RS19135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FI878_RS19140	COG1216	Glycosyl transferase, family 2
FI878_RS19165	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FI878_RS19170	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FI878_RS19175	COG1596	polysaccharide export
FI878_RS19200	COG0728	peptidoglycan biosynthetic process
FI878_RS19205	COG3023	N-Acetylmuramoyl-L-alanine amidase
FI878_RS19260	COG0546	phosphoglycolate phosphatase activity
FI878_RS19265	COG1028	Short-chain dehydrogenase reductase Sdr
FI878_RS19285	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FI878_RS19290	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FI878_RS19295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FI878_RS19300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FI878_RS19305	COG1116	anion transmembrane transporter activity
FI878_RS19310	COG1309	transcriptional regulator
FI878_RS19315	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FI878_RS19325	COG0196	riboflavin kinase activity
FI878_RS19330	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FI878_RS19340	COG1047	Peptidyl-prolyl cis-trans
FI878_RS19380	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FI878_RS19435	COG2951	lytic endotransglycosylase activity
FI878_RS19440	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FI878_RS19455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FI878_RS19465	COG0671	phosphoesterase, PA-phosphatase related
FI878_RS19470	COG0861	Integral membrane protein TerC family
FI878_RS19480	COG0754	glutathionylspermidine amidase activity
FI878_RS19490	COG0402	S-adenosylhomocysteine deaminase activity
FI878_RS19505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FI878_RS19510	COG1230	cation diffusion facilitator family transporter
FI878_RS19525	COG0706	membrane insertase activity
FI878_RS19555	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FI878_RS19555	COG2885	chlorophyll binding
FI878_RS19590	COG1132	(ABC) transporter
FI878_RS19635	COG0582	viral genome integration into host DNA
FI878_RS19650	COG2130	NADP-dependent
FI878_RS19655	COG1309	transcriptional regulator
FI878_RS19665	COG1902	pentaerythritol trinitrate reductase activity
FI878_RS19675	COG1979	alcohol dehydrogenase
FI878_RS19690	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FI878_RS19705	COG0604	alcohol dehydrogenase
FI878_RS19705	COG3321	synthase
FI878_RS19710	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FI878_RS19715	COG0583	DNA-binding transcription factor activity
FI878_RS19720	COG4221	oxidoreductase activity
FI878_RS19750	COG1733	regulation of RNA biosynthetic process
FI878_RS19755	COG1902	pentaerythritol trinitrate reductase activity
FI878_RS19760	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FI878_RS19795	COG4679	PFAM Phage derived protein Gp49-like (DUF891)
FI878_RS19910	COG1475	DNA binding
FI878_RS19915	COG1192	Involved in chromosome partitioning