locus-tag	class	description
K9C16_RS00010	COG0592	DNA-directed DNA polymerase activity
K9C16_RS00020	COG0187	DNA topoisomerase II activity
K9C16_RS00030	COG0586	Pfam SNARE associated Golgi protein
K9C16_RS00035	COG0488	(ABC) transporter
K9C16_RS00060	COG0596	Alpha beta hydrolase
K9C16_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K9C16_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K9C16_RS00110	COG0733	neurotransmitter:sodium symporter activity
K9C16_RS00120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K9C16_RS00145	COG0583	DNA-binding transcription factor activity
K9C16_RS00150	COG2233	PERMEase
K9C16_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9C16_RS00200	COG2814	Major facilitator Superfamily
K9C16_RS00205	COG0656	L-ascorbic acid biosynthetic process
K9C16_RS00210	COG0583	DNA-binding transcription factor activity
K9C16_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9C16_RS00230	COG1064	alcohol dehydrogenase
K9C16_RS00235	COG2818	Glycosylase
K9C16_RS00250	COG1194	a g-specific adenine glycosylase
K9C16_RS00270	COG2983	Belongs to the UPF0260 family
K9C16_RS00275	COG2133	pyrroloquinoline quinone binding
K9C16_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K9C16_RS00285	COG2116	formate transmembrane transporter activity
K9C16_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9C16_RS00310	COG1335	isochorismatase
K9C16_RS00315	COG0385	Bile acid
K9C16_RS00320	COG0534	Mate efflux family protein
K9C16_RS00325	COG1683	Conserved Protein
K9C16_RS00345	COG0625	glutathione transferase activity
K9C16_RS00355	COG1113	amino acid transport
K9C16_RS00365	COG0523	cobalamin synthesis protein
K9C16_RS00375	COG2188	Transcriptional regulator
K9C16_RS00405	COG0010	Belongs to the arginase family
K9C16_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K9C16_RS00440	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
K9C16_RS00445	COG0732	type I restriction modification DNA specificity domain
K9C16_RS00475	COG4584	PFAM Integrase catalytic
K9C16_RS00485	COG1484	DNA-dependent DNA replication
K9C16_RS00505	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00515	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00525	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00535	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00545	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00555	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00565	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00575	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00595	COG0673	inositol 2-dehydrogenase activity
K9C16_RS00600	COG1324	tolerance protein
K9C16_RS00610	COG1484	DNA-dependent DNA replication
K9C16_RS00645	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00650	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00660	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00670	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00680	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00690	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00700	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00710	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00715	COG2015	COG2015, Alkyl sulfatase and related hydrolases
K9C16_RS00725	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS00775	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K9C16_RS00785	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
K9C16_RS00790	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K9C16_RS00890	COG0534	Mate efflux family protein
K9C16_RS00895	COG0436	Aminotransferase
K9C16_RS00900	COG2733	membrane
K9C16_RS00915	COG2918	glutathione biosynthetic process
K9C16_RS00930	COG5632	N-Acetylmuramoyl-L-alanine amidase
K9C16_RS00930	COG3409	Peptidoglycan-binding domain 1 protein
K9C16_RS00930	COG1388	LysM domain
K9C16_RS00960	COG3150	esterase
K9C16_RS00970	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
K9C16_RS00980	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9C16_RS00990	COG2233	PERMEase
K9C16_RS01030	COG3706	GGDEF domain
K9C16_RS01045	COG1393	Belongs to the ArsC family
K9C16_RS01050	COG0708	Exodeoxyribonuclease III
K9C16_RS01070	COG0189	ligase activity
K9C16_RS01090	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K9C16_RS01100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K9C16_RS01115	COG4942	peptidase
K9C16_RS01125	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9C16_RS01135	COG2119	membrane
K9C16_RS01140	COG4774	siderophore transport
K9C16_RS01145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9C16_RS01145	COG0426	domain, Protein
K9C16_RS01170	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
K9C16_RS01190	COG1902	pentaerythritol trinitrate reductase activity
K9C16_RS01195	COG1519	Transferase
K9C16_RS01200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K9C16_RS01205	COG0668	transmembrane transport
K9C16_RS01215	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9C16_RS01220	COG1335	isochorismatase
K9C16_RS01225	COG1522	sequence-specific DNA binding
K9C16_RS01250	COG2205	protein histidine kinase activity
K9C16_RS01250	COG2198	Histidine kinase
K9C16_RS01250	COG0784	Response regulator, receiver
K9C16_RS01255	COG3162	membrane
K9C16_RS01260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9C16_RS01270	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9C16_RS01285	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K9C16_RS01290	COG1309	transcriptional regulator
K9C16_RS01310	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K9C16_RS01310	COG0352	thiamine-phosphate diphosphorylase activity
K9C16_RS01310	COG0351	phosphomethylpyrimidine kinase
K9C16_RS01320	COG2814	Major facilitator Superfamily
K9C16_RS01335	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K9C16_RS01345	COG1113	amino acid transport
K9C16_RS01355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K9C16_RS01360	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS01370	COG1335	isochorismatase
K9C16_RS01400	COG2814	Major facilitator Superfamily
K9C16_RS01405	COG0583	DNA-binding transcription factor activity
K9C16_RS01425	COG0667	Aldo Keto reductase
K9C16_RS01445	COG1733	regulation of RNA biosynthetic process
K9C16_RS01450	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9C16_RS01460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K9C16_RS01520	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K9C16_RS01535	COG2329	Antibiotic biosynthesis monooxygenase
K9C16_RS01565	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K9C16_RS01595	COG0427	acetyl-CoA hydrolase
K9C16_RS01620	COG0659	secondary active sulfate transmembrane transporter activity
K9C16_RS01625	COG4221	oxidoreductase activity
K9C16_RS01630	COG2873	o-acetylhomoserine
K9C16_RS01635	COG0488	(ABC) transporter
K9C16_RS01770	COG4372	Transposase
K9C16_RS01830	COG0582	viral genome integration into host DNA
K9C16_RS01850	COG0833	amino acid
K9C16_RS01895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K9C16_RS01900	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K9C16_RS01915	COG2226	methyltransferase
K9C16_RS01965	COG0069	glutamate synthase activity
K9C16_RS01965	COG0067	glutamate synthase
K9C16_RS01965	COG0070	glutamate synthase
K9C16_RS01970	COG0493	'glutamate synthase
K9C16_RS01980	COG1704	LemA family
K9C16_RS01985	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
K9C16_RS02005	COG3307	-O-antigen
K9C16_RS02025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K9C16_RS02040	COG0194	GDP metabolic process
K9C16_RS02090	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K9C16_RS02110	COG5380	lipid catabolic process
K9C16_RS02115	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K9C16_RS02140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9C16_RS02145	COG0277	FAD linked oxidase domain protein
K9C16_RS02155	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
K9C16_RS02160	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9C16_RS02175	COG1289	transmembrane transporter activity
K9C16_RS02185	COG0628	permease
K9C16_RS02190	COG1192	Involved in chromosome partitioning
K9C16_RS02220	COG0833	amino acid
K9C16_RS02225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K9C16_RS02230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9C16_RS02240	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS02280	COG0583	DNA-binding transcription factor activity
K9C16_RS02325	COG0517	IMP dehydrogenase activity
K9C16_RS02330	COG1983	PspC domain protein
K9C16_RS02340	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS02355	COG0408	coproporphyrinogen oxidase activity
K9C16_RS02375	COG0513	Belongs to the DEAD box helicase family
K9C16_RS02385	COG1127	ABC transporter
K9C16_RS02390	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K9C16_RS02400	COG2854	intermembrane phospholipid transfer
K9C16_RS02410	COG0598	Magnesium transport protein CorA
K9C16_RS02420	COG0494	nUDIX hydrolase
K9C16_RS02425	COG1040	competence protein
K9C16_RS02430	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K9C16_RS02450	COG1946	Acyl-CoA thioesterase
K9C16_RS02455	COG1301	dicarboxylic acid transport
K9C16_RS02470	COG1959	2 iron, 2 sulfur cluster binding
K9C16_RS02475	COG1017	nitric oxide dioxygenase activity
K9C16_RS02475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9C16_RS02485	COG0433	COG0433 Predicted ATPase
K9C16_RS02490	COG0626	cystathionine gamma-synthase activity
K9C16_RS02645	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS02650	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
K9C16_RS02680	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
K9C16_RS02685	COG0339	signal peptide processing
K9C16_RS02690	COG0557	exoribonuclease II activity
K9C16_RS02735	COG0179	Fumarylacetoacetate (FAA) hydrolase
K9C16_RS02745	COG0697	spore germination
K9C16_RS02750	COG1295	ribonuclease BN
K9C16_RS02785	COG1702	phosphate starvation-inducible protein PhoH
K9C16_RS02795	COG0739	heme binding
K9C16_RS02795	COG0741	lytic transglycosylase activity
K9C16_RS02795	COG1196	nuclear chromosome segregation
K9C16_RS02825	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K9C16_RS02830	COG1183	phosphatidylcholine synthase activity
K9C16_RS02875	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS02880	COG1309	transcriptional regulator
K9C16_RS02895	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K9C16_RS02900	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS02940	COG2969	positive regulation of protein catabolic process
K9C16_RS02950	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K9C16_RS02965	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K9C16_RS02970	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
K9C16_RS02990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K9C16_RS03000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9C16_RS03005	COG1408	metallophosphoesterase
K9C16_RS03015	COG2199	diguanylate cyclase activity
K9C16_RS03075	COG1607	acyl-coa hydrolase
K9C16_RS03105	COG2350	Protein conserved in bacteria
K9C16_RS03115	COG0613	PHP domain protein
K9C16_RS03120	COG3781	membrane
K9C16_RS03130	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K9C16_RS03135	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K9C16_RS03145	COG1862	Preprotein translocase
K9C16_RS03180	COG2205	protein histidine kinase activity
K9C16_RS03185	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K9C16_RS03200	COG0726	polysaccharide deacetylase
K9C16_RS03220	COG1091	dTDP-4-dehydrorhamnose reductase activity
K9C16_RS03235	COG1215	transferase activity, transferring glycosyl groups
K9C16_RS03285	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS03290	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS03300	COG2205	protein histidine kinase activity
K9C16_RS03305	COG0745	RESPONSE REGULATOR receiver
K9C16_RS03310	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
K9C16_RS03330	COG2096	Adenosyltransferase
K9C16_RS03380	COG0285	dihydrofolate synthase activity
K9C16_RS03400	COG0450	alkyl hydroperoxide reductase
K9C16_RS03415	COG0477	Major facilitator Superfamily
K9C16_RS03420	COG1272	protein, Hemolysin III
K9C16_RS03450	COG0183	Belongs to the thiolase family
K9C16_RS03455	COG2207	Transcriptional regulator
K9C16_RS03475	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9C16_RS03495	COG0183	Belongs to the thiolase family
K9C16_RS03505	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9C16_RS03505	COG2885	chlorophyll binding
K9C16_RS03515	COG1690	Belongs to the RtcB family
K9C16_RS03520	COG0833	amino acid
K9C16_RS03530	COG2233	PERMEase
K9C16_RS03535	COG1217	gtp-binding protein TYPA
K9C16_RS03560	COG2094	Belongs to the DNA glycosylase MPG family
K9C16_RS03565	COG4772	TonB-dependent receptor
K9C16_RS03570	COG1902	pentaerythritol trinitrate reductase activity
K9C16_RS03585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9C16_RS03590	COG0354	folic acid binding
K9C16_RS03600	COG3189	MarR family transcriptional regulator
K9C16_RS03605	COG2824	Alkylphosphonate utilization operon protein PhnA
K9C16_RS03610	COG3422	double-strand break repair
K9C16_RS03650	COG0840	transmembrane signaling receptor activity
K9C16_RS03665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K9C16_RS03680	COG5510	response to toxic substance
K9C16_RS03690	COG2832	Protein of unknown function (DUF454)
K9C16_RS03695	COG1376	ErfK ybiS ycfS ynhG family protein
K9C16_RS03730	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K9C16_RS03740	COG1289	transmembrane transporter activity
K9C16_RS03745	COG2814	Major facilitator Superfamily
K9C16_RS03765	COG1115	amino acid carrier protein
K9C16_RS03770	COG1752	Esterase of the alpha-beta hydrolase superfamily
K9C16_RS03775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K9C16_RS03780	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
K9C16_RS03785	COG3590	peptidase
K9C16_RS03810	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K9C16_RS03820	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K9C16_RS03825	COG1077	Cell shape determining protein MreB Mrl
K9C16_RS03830	COG1792	Involved in formation and maintenance of cell shape
K9C16_RS03835	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
K9C16_RS03840	COG0424	maF-like protein
K9C16_RS03845	COG1530	ribonuclease E activity
K9C16_RS03855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9C16_RS03865	COG0560	Phosphoserine phosphatase
K9C16_RS03875	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9C16_RS03900	COG2207	Transcriptional regulator
K9C16_RS03920	COG1113	amino acid transport
K9C16_RS03925	COG2828	Protein conserved in bacteria
K9C16_RS03930	COG0142	geranyltranstransferase activity
K9C16_RS03935	COG2315	Protein conserved in bacteria
K9C16_RS03950	COG1752	Esterase of the alpha-beta hydrolase superfamily
K9C16_RS03970	COG2194	sulfuric ester hydrolase activity
K9C16_RS03975	COG0745	RESPONSE REGULATOR receiver
K9C16_RS03980	COG0642	Histidine kinase
K9C16_RS03990	COG0004	ammonium transporteR
K9C16_RS03995	COG0583	DNA-binding transcription factor activity
K9C16_RS04015	COG0525	valine-tRNA ligase activity
K9C16_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS04035	COG0393	Putative heavy-metal-binding
K9C16_RS04040	COG0393	Putative heavy-metal-binding
K9C16_RS04045	COG1538	Outer membrane efflux protein
K9C16_RS04055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9C16_RS04060	COG0671	phosphoesterase, PA-phosphatase related
K9C16_RS04090	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
K9C16_RS04105	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K9C16_RS04105	COG1648	precorrin-2 dehydrogenase activity
K9C16_RS04110	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K9C16_RS04115	COG1733	regulation of RNA biosynthetic process
K9C16_RS04125	COG0531	amino acid
K9C16_RS04140	COG0321	lipoyl(octanoyl) transferase activity
K9C16_RS04145	COG2921	Belongs to the UPF0250 family
K9C16_RS04180	COG2009	succinate dehydrogenase
K9C16_RS04185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
K9C16_RS04190	COG1053	succinate dehydrogenase
K9C16_RS04195	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
K9C16_RS04220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9C16_RS04240	COG2354	Protein conserved in bacteria
K9C16_RS04245	COG2321	neutral zinc metallopeptidase
K9C16_RS04265	COG2843	Capsule synthesis protein
K9C16_RS04280	COG0589	response to stress
K9C16_RS04290	COG0251	oxidation-reduction process
K9C16_RS04310	COG0505	Belongs to the CarA family
K9C16_RS04335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K9C16_RS04340	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K9C16_RS04400	COG0477	Major facilitator Superfamily
K9C16_RS04405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K9C16_RS04420	COG1597	lipid kinase activity
K9C16_RS04425	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K9C16_RS04450	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9C16_RS04455	COG0584	glycerophosphoryl diester phosphodiesterase
K9C16_RS04475	COG0741	lytic transglycosylase activity
K9C16_RS04495	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9C16_RS04510	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9C16_RS04535	COG3811	Belongs to the UPF0386 family
K9C16_RS04555	COG0778	Nitroreductase
K9C16_RS04570	COG1929	Belongs to the glycerate kinase type-1 family
K9C16_RS04575	COG0243	molybdopterin cofactor binding
K9C16_RS04580	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K9C16_RS04585	COG3339	Conserved Protein
K9C16_RS04595	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
K9C16_RS04610	COG1113	amino acid transport
K9C16_RS04620	COG0019	diaminopimelate decarboxylase activity
K9C16_RS04630	COG1280	lysine exporter protein (LysE YggA)
K9C16_RS04635	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K9C16_RS04665	COG0463	Glycosyl transferase, family 2
K9C16_RS04685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9C16_RS04720	COG4591	ABC-type transport system involved in lipoprotein release permease component
K9C16_RS04725	COG1136	(ABC) transporter
K9C16_RS04730	COG0658	competence protein
K9C16_RS04730	COG2333	competence protein COMEC
K9C16_RS04740	COG0616	signal peptide processing
K9C16_RS04740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K9C16_RS04745	COG0596	Alpha beta hydrolase
K9C16_RS04750	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K9C16_RS04760	COG0628	permease
K9C16_RS04795	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9C16_RS04815	COG0823	Involved in the tonB-independent uptake of proteins
K9C16_RS04835	COG0824	Thioesterase
K9C16_RS04840	COG1473	amidohydrolase
K9C16_RS04860	COG0047	phosphoribosylformylglycinamidine synthase activity
K9C16_RS04860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K9C16_RS04865	COG2814	Major facilitator Superfamily
K9C16_RS04875	COG1024	Enoyl-CoA hydratase
K9C16_RS04880	COG1051	belongs to the nudix hydrolase family
K9C16_RS04880	COG1056	cytidyltransferase-related domain
K9C16_RS04890	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K9C16_RS04905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
K9C16_RS04920	COG4625	pathogenesis
K9C16_RS04925	COG0583	DNA-binding transcription factor activity
K9C16_RS04930	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
K9C16_RS04935	COG4208	sulfate ABC transporter
K9C16_RS04940	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
K9C16_RS04950	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K9C16_RS04955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K9C16_RS04960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K9C16_RS04980	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9C16_RS04995	COG0681	Belongs to the peptidase S26 family
K9C16_RS05010	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K9C16_RS05020	COG1381	Involved in DNA repair and RecF pathway recombination
K9C16_RS05025	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K9C16_RS05035	COG4221	oxidoreductase activity
K9C16_RS05065	COG0443	Heat shock 70 kDa protein
K9C16_RS05075	COG0436	Aminotransferase
K9C16_RS05095	COG0556	nucleotide-excision repair
K9C16_RS05150	COG2070	2-Nitropropane dioxygenase
K9C16_RS05180	COG1215	transferase activity, transferring glycosyl groups
K9C16_RS05195	COG0415	Belongs to the DNA photolyase family
K9C16_RS05205	COG1252	NADH dehydrogenase
K9C16_RS05210	COG1686	Belongs to the peptidase S11 family
K9C16_RS05225	COG1187	pseudouridine synthase activity
K9C16_RS05250	COG0477	Major facilitator Superfamily
K9C16_RS05255	COG0583	DNA-binding transcription factor activity
K9C16_RS05260	COG1823	symporter activity
K9C16_RS05270	COG0612	Peptidase, M16
K9C16_RS05295	COG0352	thiamine-phosphate diphosphorylase activity
K9C16_RS05330	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9C16_RS05340	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9C16_RS05355	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K9C16_RS05360	COG0076	glutamate decarboxylase activity
K9C16_RS05370	COG1522	sequence-specific DNA binding
K9C16_RS05375	COG3961	Belongs to the TPP enzyme family
K9C16_RS05380	COG1113	amino acid transport
K9C16_RS05385	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K9C16_RS05390	COG0573	inorganic phosphate transmembrane transporter activity
K9C16_RS05400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K9C16_RS05405	COG0616	signal peptide processing
K9C16_RS05440	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
K9C16_RS05445	COG1686	Belongs to the peptidase S11 family
K9C16_RS05470	COG0583	DNA-binding transcription factor activity
K9C16_RS05475	COG1067	ATP-dependent peptidase activity
K9C16_RS05500	COG4943	cyclic-guanylate-specific phosphodiesterase activity
K9C16_RS05530	COG1966	Carbon starvation protein
K9C16_RS05535	COG2879	small protein
K9C16_RS05545	COG2130	NADP-dependent
K9C16_RS05570	COG1741	Belongs to the pirin family
K9C16_RS05580	COG2964	Protein conserved in bacteria
K9C16_RS05595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9C16_RS05600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9C16_RS05605	COG4605	iron ion homeostasis
K9C16_RS05610	COG4604	ABC transporter, ATP-binding protein
K9C16_RS05615	COG4607	ABC-type enterochelin transport system periplasmic component
K9C16_RS05620	COG4774	siderophore transport
K9C16_RS05630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9C16_RS05635	COG1021	2,3-dihydroxybenzoate-AMP ligase
K9C16_RS05640	COG1535	isochorismatase
K9C16_RS05640	COG3433	isochorismatase activity
K9C16_RS05655	COG1132	(ABC) transporter
K9C16_RS05660	COG1132	(ABC) transporter
K9C16_RS05665	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
K9C16_RS05670	COG2977	Belongs to the P-Pant transferase superfamily
K9C16_RS05675	COG1169	isochorismate synthase
K9C16_RS05690	COG3739	integral membrane protein
K9C16_RS05710	COG0302	gtp cyclohydrolase
K9C16_RS05720	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K9C16_RS05750	COG0308	aminopeptidase N
K9C16_RS05755	COG0512	Glutamine amidotransferase of anthranilate synthase
K9C16_RS05960	COG5410	chromosome segregation
K9C16_RS06055	COG1598	PFAM Uncharacterised protein family UPF0150
K9C16_RS06100	COG0739	heme binding
K9C16_RS06100	COG0741	lytic transglycosylase activity
K9C16_RS06100	COG1196	nuclear chromosome segregation
K9C16_RS06145	COG0582	viral genome integration into host DNA
K9C16_RS06160	COG0174	glutamine synthetase
K9C16_RS06170	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K9C16_RS06205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K9C16_RS06210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
K9C16_RS06215	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9C16_RS06235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
K9C16_RS06240	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
K9C16_RS06245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K9C16_RS06260	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS06265	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K9C16_RS06270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9C16_RS06280	COG2223	nitrite transmembrane transporter activity
K9C16_RS06310	COG0024	Methionine aminopeptidase
K9C16_RS06315	COG0052	Belongs to the universal ribosomal protein uS2 family
K9C16_RS06330	COG2207	Transcriptional regulator
K9C16_RS06355	COG2951	lytic endotransglycosylase activity
K9C16_RS06360	COG0772	Belongs to the SEDS family
K9C16_RS06375	COG0842	Transport permease protein
K9C16_RS06380	COG1131	(ABC) transporter
K9C16_RS06425	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9C16_RS06440	COG4215	(ABC) transporter
K9C16_RS06445	COG4160	amino acid transport
K9C16_RS06450	COG4598	ABC transporter
K9C16_RS06460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9C16_RS06465	COG0826	peptidase U32
K9C16_RS06470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9C16_RS06485	COG1720	tRNA m6t6A37 methyltransferase activity
K9C16_RS06495	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
K9C16_RS06510	COG0642	Histidine kinase
K9C16_RS06520	COG0494	nUDIX hydrolase
K9C16_RS06530	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K9C16_RS06535	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K9C16_RS06540	COG3139	Protein of unknown function (DUF1315)
K9C16_RS06545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K9C16_RS06550	COG1301	dicarboxylic acid transport
K9C16_RS06555	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS06560	COG2819	hydrolase of the alpha beta superfamily
K9C16_RS06570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K9C16_RS06580	COG2195	Cleaves the N-terminal amino acid of tripeptides
K9C16_RS06585	COG1234	tRNA 3'-trailer cleavage
K9C16_RS06615	COG2363	Small membrane protein
K9C16_RS06640	COG0513	Belongs to the DEAD box helicase family
K9C16_RS06650	COG0778	Nitroreductase
K9C16_RS06680	COG1286	toxin biosynthetic process
K9C16_RS06705	COG4783	chaperone-mediated protein folding
K9C16_RS06710	COG1610	YqeY-like protein
K9C16_RS06780	COG3210	domain, Protein
K9C16_RS06780	COG3210	domain, Protein
K9C16_RS06865	COG3111	PFAM Bacterial OB fold (BOF) protein
K9C16_RS06890	COG3243	poly(R)-hydroxyalkanoic acid synthase
K9C16_RS06895	COG0786	glutamate:sodium symporter activity
K9C16_RS06905	COG2186	Transcriptional regulator
K9C16_RS06955	COG0477	Major facilitator Superfamily
K9C16_RS06980	COG2985	domain, Protein
K9C16_RS06995	COG2995	paraquat-inducible protein a
K9C16_RS07000	COG3008	intermembrane lipid transfer
K9C16_RS07000	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K9C16_RS07010	COG2351	hydroxyisourate hydrolase activity
K9C16_RS07050	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K9C16_RS07060	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K9C16_RS07065	COG0642	Histidine kinase
K9C16_RS07070	COG0745	RESPONSE REGULATOR receiver
K9C16_RS07090	COG1794	racemase activity, acting on amino acids and derivatives
K9C16_RS07120	COG1301	dicarboxylic acid transport
K9C16_RS07130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9C16_RS07135	COG2011	ABC-type metal ion transport system permease component
K9C16_RS07140	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K9C16_RS07145	COG1464	Belongs to the NlpA lipoprotein family
K9C16_RS07150	COG0151	Belongs to the GarS family
K9C16_RS07155	COG0138	bifunctional purine biosynthesis protein purh
K9C16_RS07160	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
K9C16_RS07190	COG2308	Evidence 4 Homologs of previously reported genes of
K9C16_RS07200	COG1305	Transglutaminase-like
K9C16_RS07210	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9C16_RS07215	COG0305	Participates in initiation and elongation during chromosome replication
K9C16_RS07240	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
K9C16_RS07250	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K9C16_RS07255	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K9C16_RS07280	COG0726	polysaccharide deacetylase
K9C16_RS07280	COG1649	PFAM Uncharacterised BCR, COG1649
K9C16_RS07285	COG1215	transferase activity, transferring glycosyl groups
K9C16_RS07290	COG3658	cytochrome
K9C16_RS07300	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9C16_RS07345	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS07350	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9C16_RS07355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9C16_RS07380	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K9C16_RS07385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K9C16_RS07395	COG2205	protein histidine kinase activity
K9C16_RS07400	COG0745	RESPONSE REGULATOR receiver
K9C16_RS07405	COG3293	Transposase
K9C16_RS07410	COG0174	glutamine synthetase
K9C16_RS07430	COG0729	surface antigen
K9C16_RS07455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9C16_RS07460	COG2814	Major facilitator Superfamily
K9C16_RS07475	COG0583	DNA-binding transcription factor activity
K9C16_RS07490	COG1187	pseudouridine synthase activity
K9C16_RS07510	COG0802	atpase or kinase
K9C16_RS07515	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K9C16_RS07525	COG1923	regulation of RNA biosynthetic process
K9C16_RS07530	COG0697	spore germination
K9C16_RS07555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9C16_RS07560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K9C16_RS07560	COG0519	Catalyzes the synthesis of GMP from XMP
K9C16_RS07565	COG4302	ethanolamine ammonia-lyase activity
K9C16_RS07570	COG4303	Ethanolamine ammonia lyase large subunit
K9C16_RS07575	COG0531	amino acid
K9C16_RS07595	COG1454	alcohol dehydrogenase
K9C16_RS07600	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9C16_RS07625	COG0308	aminopeptidase N
K9C16_RS07665	COG1605	Chorismate mutase
K9C16_RS07685	COG1309	transcriptional regulator
K9C16_RS07695	COG0668	transmembrane transport
K9C16_RS07705	COG3293	Transposase
K9C16_RS07730	COG4773	Receptor
K9C16_RS07750	COG0488	(ABC) transporter
K9C16_RS07755	COG0589	response to stress
K9C16_RS07780	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
K9C16_RS07790	COG3135	benzoate transporter
K9C16_RS07795	COG1522	sequence-specific DNA binding
K9C16_RS07805	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K9C16_RS07810	COG0583	DNA-binding transcription factor activity
K9C16_RS07820	COG0183	Belongs to the thiolase family
K9C16_RS07830	COG2030	dehydratase
K9C16_RS07835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K9C16_RS07860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K9C16_RS07870	COG0824	Thioesterase
K9C16_RS07875	COG1454	alcohol dehydrogenase
K9C16_RS07885	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
K9C16_RS07915	COG0069	glutamate synthase activity
K9C16_RS08115	COG5410	chromosome segregation
K9C16_RS08205	COG1598	PFAM Uncharacterised protein family UPF0150
K9C16_RS08300	COG2814	Major facilitator Superfamily
K9C16_RS08315	COG0511	ligase activity, forming carbon-carbon bonds
K9C16_RS08335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9C16_RS08335	COG1116	anion transmembrane transporter activity
K9C16_RS08340	COG0745	RESPONSE REGULATOR receiver
K9C16_RS08350	COG2146	nitrite reductase [NAD(P)H] activity
K9C16_RS08350	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9C16_RS08355	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9C16_RS08360	COG0243	molybdopterin cofactor binding
K9C16_RS08370	COG0243	molybdopterin cofactor binding
K9C16_RS08375	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
K9C16_RS08390	COG0521	Mo-molybdopterin cofactor biosynthetic process
K9C16_RS08390	COG0315	cyclic pyranopterin monophosphate synthase activity
K9C16_RS08395	COG0303	'Molybdopterin
K9C16_RS08405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9C16_RS08410	COG0697	spore germination
K9C16_RS08430	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
K9C16_RS08435	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K9C16_RS08490	COG2204	response regulator
K9C16_RS08495	COG3852	Histidine kinase
K9C16_RS08520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K9C16_RS08525	COG0575	Belongs to the CDS family
K9C16_RS08540	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9C16_RS08560	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9C16_RS08575	COG2137	regulation of response to DNA damage stimulus
K9C16_RS08585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
K9C16_RS08590	COG1011	Hydrolase
K9C16_RS08615	COG1522	sequence-specific DNA binding
K9C16_RS08625	COG1113	amino acid transport
K9C16_RS08645	COG0659	secondary active sulfate transmembrane transporter activity
K9C16_RS08650	COG2135	peptidase activity
K9C16_RS08685	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
K9C16_RS08685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9C16_RS08685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
K9C16_RS08690	COG1105	Belongs to the carbohydrate kinase PfkB family
K9C16_RS08695	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K9C16_RS08695	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9C16_RS08725	COG0024	Methionine aminopeptidase
K9C16_RS08730	COG0583	DNA-binding transcription factor activity
K9C16_RS08740	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K9C16_RS08745	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9C16_RS08750	COG0516	GMP reductase activity
K9C16_RS08750	COG0517	IMP dehydrogenase activity
K9C16_RS08775	COG0552	protein localization to endoplasmic reticulum
K9C16_RS08785	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
K9C16_RS08795	COG4890	Cyd operon protein YbgT
K9C16_RS08800	COG1294	oxidase, subunit
K9C16_RS08815	COG1585	Membrane protein implicated in regulation of membrane protease activity
K9C16_RS08825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9C16_RS08830	COG4774	siderophore transport
K9C16_RS08845	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K9C16_RS08850	COG0569	domain protein
K9C16_RS08855	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K9C16_RS08885	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K9C16_RS08890	COG0542	response to heat
K9C16_RS08915	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9C16_RS08915	COG1902	pentaerythritol trinitrate reductase activity
K9C16_RS08960	COG2323	membrane
K9C16_RS08965	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
K9C16_RS08975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K9C16_RS08980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K9C16_RS08985	COG0183	Belongs to the thiolase family
K9C16_RS08990	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K9C16_RS08995	COG0596	Alpha beta hydrolase
K9C16_RS09000	COG2271	Major facilitator Superfamily
K9C16_RS09005	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9C16_RS09010	COG3485	protocatechuate 3,4-dioxygenase
K9C16_RS09015	COG3485	protocatechuate 3,4-dioxygenase
K9C16_RS09020	COG0710	3-dehydroquinate dehydratase activity
K9C16_RS09025	COG3420	alginic acid biosynthetic process
K9C16_RS09030	COG3659	wide pore channel activity
K9C16_RS09035	COG4993	Dehydrogenase
K9C16_RS09045	COG2391	methyltransferase activity
K9C16_RS09060	COG1414	Transcriptional regulator
K9C16_RS09065	COG0583	DNA-binding transcription factor activity
K9C16_RS09070	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS09095	COG2814	Major facilitator Superfamily
K9C16_RS09105	COG0154	amidase activity
K9C16_RS09125	COG4638	Rieske (2fe-2S)
K9C16_RS09135	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS09145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9C16_RS09155	COG3733	amine oxidase
K9C16_RS09165	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS09170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9C16_RS09175	COG0183	Belongs to the thiolase family
K9C16_RS09180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K9C16_RS09185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K9C16_RS09195	COG4829	muconolactone delta-isomerase
K9C16_RS09200	COG4948	Mandelate Racemase Muconate Lactonizing
K9C16_RS09205	COG0583	DNA-binding transcription factor activity
K9C16_RS09215	COG2186	Transcriptional regulator
K9C16_RS09235	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS09250	COG1902	pentaerythritol trinitrate reductase activity
K9C16_RS09250	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9C16_RS09265	COG0789	Transcriptional regulator
K9C16_RS09295	COG1309	transcriptional regulator
K9C16_RS09300	COG0583	DNA-binding transcription factor activity
K9C16_RS09305	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS09310	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS09325	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS09335	COG0318	PFAM AMP-dependent synthetase and ligase
K9C16_RS09385	COG2188	Transcriptional regulator
K9C16_RS09400	COG0583	DNA-binding transcription factor activity
K9C16_RS09435	COG1566	PFAM secretion protein HlyD family protein
K9C16_RS09470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9C16_RS09490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9C16_RS09525	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K9C16_RS09530	COG2814	Major facilitator Superfamily
K9C16_RS09540	COG0179	Fumarylacetoacetate (FAA) hydrolase
K9C16_RS09550	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS09555	COG3384	dioxygenase
K9C16_RS09565	COG3971	2-oxopent-4-enoate hydratase activity
K9C16_RS09580	COG0477	Major facilitator Superfamily
K9C16_RS09585	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS09590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9C16_RS09595	COG1846	Transcriptional regulator
K9C16_RS09600	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS09605	COG0129	dihydroxy-acid dehydratase activity
K9C16_RS09615	COG0583	DNA-binding transcription factor activity
K9C16_RS09620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9C16_RS09630	COG2084	Dehydrogenase
K9C16_RS09635	COG2207	Transcriptional regulator
K9C16_RS09640	COG1064	alcohol dehydrogenase
K9C16_RS09650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9C16_RS09655	COG1120	ATPase activity
K9C16_RS09675	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K9C16_RS09765	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS09780	COG2207	Transcriptional regulator
K9C16_RS09790	COG2205	protein histidine kinase activity
K9C16_RS09795	COG0745	RESPONSE REGULATOR receiver
K9C16_RS09800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9C16_RS09805	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9C16_RS09875	COG3539	Fimbrial protein
K9C16_RS09900	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K9C16_RS09910	COG0753	catalase activity
K9C16_RS09925	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9C16_RS09935	COG3293	Transposase
K9C16_RS10000	COG1535	isochorismatase
K9C16_RS10000	COG3433	isochorismatase activity
K9C16_RS10005	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS10010	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
K9C16_RS10015	COG4149	molybdate abc transporter
K9C16_RS10020	COG0725	ABC transporter, periplasmic molybdate-binding protein
K9C16_RS10030	COG4638	Rieske (2fe-2S)
K9C16_RS10035	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
K9C16_RS10040	COG0543	2 iron, 2 sulfur cluster binding
K9C16_RS10040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9C16_RS10055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9C16_RS10065	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS10080	COG2207	Transcriptional regulator
K9C16_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS10090	COG2610	gluconate transmembrane transporter activity
K9C16_RS10095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9C16_RS10125	COG0583	DNA-binding transcription factor activity
K9C16_RS10140	COG2031	fatty acid transporter
K9C16_RS10145	COG0183	Belongs to the thiolase family
K9C16_RS10150	COG0583	DNA-binding transcription factor activity
K9C16_RS10155	COG0583	DNA-binding transcription factor activity
K9C16_RS10170	COG1027	Aspartate ammonia-lyase
K9C16_RS10180	COG0477	Major facilitator Superfamily
K9C16_RS10200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9C16_RS10205	COG4521	taurine ABC transporter
K9C16_RS10220	COG2188	Transcriptional regulator
K9C16_RS10230	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K9C16_RS10235	COG1733	regulation of RNA biosynthetic process
K9C16_RS10240	COG2207	Transcriptional regulator
K9C16_RS10240	COG3708	Transcriptional regulator
K9C16_RS10255	COG0730	response to heat
K9C16_RS10280	COG3781	membrane
K9C16_RS10285	COG1063	alcohol dehydrogenase
K9C16_RS10295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9C16_RS10300	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9C16_RS10305	COG0022	dehydrogenase e1 component
K9C16_RS10310	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K9C16_RS10315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K9C16_RS10345	COG0133	tryptophan synthase activity
K9C16_RS10355	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K9C16_RS10390	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K9C16_RS10415	COG2226	methyltransferase
K9C16_RS10470	COG0842	Transport permease protein
K9C16_RS10475	COG0842	Transport permease protein
K9C16_RS10480	COG1131	(ABC) transporter
K9C16_RS10495	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9C16_RS10500	COG4773	Receptor
K9C16_RS10520	COG0730	response to heat
K9C16_RS10525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
K9C16_RS10540	COG0406	alpha-ribazole phosphatase activity
K9C16_RS10545	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K9C16_RS10560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9C16_RS10590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K9C16_RS10600	COG4264	IucA IucC family
K9C16_RS10605	COG4264	IucA IucC family
K9C16_RS10610	COG2814	Major facilitator Superfamily
K9C16_RS10625	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
K9C16_RS10640	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS10645	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS10655	COG2826	transposase and inactivated derivatives, IS30 family
K9C16_RS10665	COG2207	Transcriptional regulator
K9C16_RS10670	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9C16_RS10675	COG0776	regulation of translation
K9C16_RS10700	COG0822	iron-sulfur transferase activity
K9C16_RS10705	COG0316	Belongs to the HesB IscA family
K9C16_RS10735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K9C16_RS10755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
K9C16_RS10760	COG0702	epimerase
K9C16_RS10795	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9C16_RS10805	COG0339	signal peptide processing
K9C16_RS10850	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K9C16_RS10855	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K9C16_RS10885	COG0776	regulation of translation
K9C16_RS10950	COG0084	hydrolase, TatD family'
K9C16_RS10970	COG1663	tetraacyldisaccharide 4'-kinase activity
K9C16_RS10975	COG1132	(ABC) transporter
K9C16_RS10985	COG0811	peptide transport
K9C16_RS10990	COG1475	DNA binding
K9C16_RS10995	COG1192	Involved in chromosome partitioning
K9C16_RS11005	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K9C16_RS11020	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9C16_RS11025	COG0191	fructose-bisphosphate aldolase activity
K9C16_RS11045	COG0424	maF-like protein
K9C16_RS11050	COG2850	peptidyl-arginine hydroxylation
K9C16_RS11060	COG0640	Transcriptional regulator
K9C16_RS11070	COG3619	membrane
K9C16_RS11075	COG3122	Protein conserved in bacteria
K9C16_RS11080	COG1132	(ABC) transporter
K9C16_RS11100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K9C16_RS11105	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
K9C16_RS11115	COG0506	proline dehydrogenase activity
K9C16_RS11115	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K9C16_RS11115	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K9C16_RS11120	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
K9C16_RS11135	COG3698	Phosphodiester glycosidase
K9C16_RS11145	COG2353	YceI-like domain
K9C16_RS11155	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
K9C16_RS11200	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K9C16_RS11200	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K9C16_RS11225	COG3539	Fimbrial protein
K9C16_RS11230	COG3121	Chaperone
K9C16_RS11255	COG0697	spore germination
K9C16_RS11265	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K9C16_RS11275	COG0583	DNA-binding transcription factor activity
K9C16_RS11295	COG1309	transcriptional regulator
K9C16_RS11310	COG1522	sequence-specific DNA binding
K9C16_RS11320	COG1126	abc transporter atp-binding protein
K9C16_RS11325	COG0765	amino acid transport
K9C16_RS11330	COG0765	amino acid transport
K9C16_RS11360	COG1464	Belongs to the NlpA lipoprotein family
K9C16_RS11370	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
K9C16_RS11375	COG2011	ABC-type metal ion transport system permease component
K9C16_RS11380	COG0012	GTP binding
K9C16_RS11405	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
K9C16_RS11445	COG0386	Belongs to the glutathione peroxidase family
K9C16_RS11455	COG0436	Aminotransferase
K9C16_RS11495	COG3634	alkyl hydroperoxide reductase activity
K9C16_RS11510	COG0583	DNA-binding transcription factor activity
K9C16_RS11515	COG0798	PFAM Bile acid sodium symporter
K9C16_RS11520	COG0640	Transcriptional regulator
K9C16_RS11535	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K9C16_RS11545	COG0583	DNA-binding transcription factor activity
K9C16_RS11555	COG1953	Uracil, thiamine, allantoin
K9C16_RS11565	COG2175	clavaminate synthase activity
K9C16_RS11570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9C16_RS11575	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
K9C16_RS11580	COG4521	taurine ABC transporter
K9C16_RS11600	COG0477	Major facilitator Superfamily
K9C16_RS11620	COG1271	oxidase subunit
K9C16_RS11625	COG1294	oxidase, subunit
K9C16_RS11635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9C16_RS11655	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K9C16_RS11675	COG3052	prosthetic group binding
K9C16_RS11680	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
K9C16_RS11690	COG0583	DNA-binding transcription factor activity
K9C16_RS11700	COG2814	Major facilitator Superfamily
K9C16_RS11720	COG1346	cytolysis
K9C16_RS11730	COG0583	DNA-binding transcription factor activity
K9C16_RS11735	COG0625	glutathione transferase activity
K9C16_RS11740	COG0625	glutathione transferase activity
K9C16_RS11745	COG0583	DNA-binding transcription factor activity
K9C16_RS11760	COG1045	serine acetyltransferase
K9C16_RS11765	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9C16_RS11770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K9C16_RS11775	COG1280	lysine exporter protein (LysE YggA)
K9C16_RS11790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9C16_RS11795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9C16_RS11805	COG0765	amino acid transport
K9C16_RS11810	COG0765	amino acid transport
K9C16_RS11830	COG0784	Response regulator, receiver
K9C16_RS11830	COG2205	protein histidine kinase activity
K9C16_RS11850	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K9C16_RS11875	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS11925	COG0583	DNA-binding transcription factor activity
K9C16_RS11945	COG0318	PFAM AMP-dependent synthetase and ligase
K9C16_RS11950	COG1309	transcriptional regulator
K9C16_RS11955	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS11960	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K9C16_RS11965	COG1024	Enoyl-CoA hydratase
K9C16_RS11970	COG4770	biotin carboxylase activity
K9C16_RS11980	COG0583	DNA-binding transcription factor activity
K9C16_RS11995	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS12005	COG2814	Major facilitator Superfamily
K9C16_RS12015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
K9C16_RS12020	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
K9C16_RS12025	COG2814	Major facilitator Superfamily
K9C16_RS12030	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS12035	COG1024	Enoyl-CoA hydratase
K9C16_RS12040	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS12045	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9C16_RS12050	COG0183	Belongs to the thiolase family
K9C16_RS12060	COG2814	Major facilitator Superfamily
K9C16_RS12070	COG1024	Enoyl-CoA hydratase
K9C16_RS12085	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS12090	COG2814	Major facilitator Superfamily
K9C16_RS12095	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9C16_RS12100	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K9C16_RS12115	COG3842	ATPase activity
K9C16_RS12120	COG1840	ABC-type Fe3 transport system, periplasmic component
K9C16_RS12135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9C16_RS12140	COG1414	Transcriptional regulator
K9C16_RS12150	COG0583	DNA-binding transcription factor activity
K9C16_RS12155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9C16_RS12160	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS12170	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
K9C16_RS12180	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS12185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9C16_RS12190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9C16_RS12195	COG2267	carboxylic ester hydrolase activity
K9C16_RS12215	COG3038	cytochrome b561
K9C16_RS12220	COG0753	catalase activity
K9C16_RS12225	COG2271	Major facilitator Superfamily
K9C16_RS12230	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K9C16_RS12235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9C16_RS12260	COG2050	protein possibly involved in aromatic compounds catabolism
K9C16_RS12270	COG3327	negative regulation of DNA-templated transcription, initiation
K9C16_RS12275	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
K9C16_RS12280	COG0183	Belongs to the thiolase family
K9C16_RS12285	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9C16_RS12290	COG1024	Enoyl-CoA hydratase
K9C16_RS12295	COG1024	Enoyl-CoA hydratase
K9C16_RS12300	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9C16_RS12305	COG2151	metal-sulfur cluster biosynthetic enzyme
K9C16_RS12310	COG3396	Phenylacetate-CoA oxygenase
K9C16_RS12315	COG3460	Phenylacetate-CoA oxygenase
K9C16_RS12320	COG3396	Phenylacetate-CoA oxygenase
K9C16_RS12325	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS12325	COG2030	dehydratase
K9C16_RS12330	COG1760	l-serine dehydratase
K9C16_RS12335	COG0531	amino acid
K9C16_RS12340	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS12365	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9C16_RS12385	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9C16_RS12395	COG0789	Transcriptional regulator
K9C16_RS12405	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K9C16_RS12420	COG2807	transmembrane transport
K9C16_RS12425	COG0590	tRNA wobble adenosine to inosine editing
K9C16_RS12475	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9C16_RS12515	COG3657	addiction module killer protein
K9C16_RS12520	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9C16_RS12530	COG2801	Transposase and inactivated derivatives
K9C16_RS12600	COG1011	Hydrolase
K9C16_RS12620	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9C16_RS12640	COG2814	Major facilitator Superfamily
K9C16_RS12660	COG0598	Magnesium transport protein CorA
K9C16_RS12665	COG1560	Kdo2-lipid A biosynthetic process
K9C16_RS12675	COG5006	permease, DMT superfamily
K9C16_RS12680	COG1522	sequence-specific DNA binding
K9C16_RS12695	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K9C16_RS12705	COG4122	O-methyltransferase activity
K9C16_RS12740	COG1137	ATPase activity
K9C16_RS12745	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
K9C16_RS12755	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
K9C16_RS12760	COG0517	IMP dehydrogenase activity
K9C16_RS12760	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K9C16_RS12800	COG2814	Major facilitator Superfamily
K9C16_RS12835	COG1278	Cold shock
K9C16_RS12840	COG1280	lysine exporter protein (LysE YggA)
K9C16_RS12870	COG1570	exodeoxyribonuclease VII activity
K9C16_RS12955	COG2871	sodium ion transport
K9C16_RS12965	COG0583	DNA-binding transcription factor activity
K9C16_RS12975	COG4638	Rieske (2fe-2S)
K9C16_RS12985	COG0543	2 iron, 2 sulfur cluster binding
K9C16_RS12985	COG0633	Ferredoxin
K9C16_RS12990	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS12995	COG3135	benzoate transporter
K9C16_RS13000	COG2814	Major facilitator Superfamily
K9C16_RS13015	COG1643	Atp-dependent helicase
K9C16_RS13020	COG0450	alkyl hydroperoxide reductase
K9C16_RS13030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K9C16_RS13040	COG3634	alkyl hydroperoxide reductase activity
K9C16_RS13065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K9C16_RS13070	COG0625	glutathione transferase activity
K9C16_RS13080	COG2885	chlorophyll binding
K9C16_RS13115	COG0542	response to heat
K9C16_RS13130	COG1765	OsmC-like protein
K9C16_RS13145	COG0667	Aldo Keto reductase
K9C16_RS13160	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K9C16_RS13175	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
K9C16_RS13185	COG0527	aspartate kinase activity
K9C16_RS13195	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K9C16_RS13205	COG3038	cytochrome b561
K9C16_RS13210	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
K9C16_RS13215	COG2252	PERMEase
K9C16_RS13225	COG2072	flavoprotein involved in K transport
K9C16_RS13240	COG1741	Belongs to the pirin family
K9C16_RS13245	COG1309	transcriptional regulator
K9C16_RS13255	COG0300	oxidoreductase activity
K9C16_RS13260	COG2072	flavoprotein involved in K transport
K9C16_RS13265	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
K9C16_RS13310	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9C16_RS13325	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
K9C16_RS13340	COG2814	Major facilitator Superfamily
K9C16_RS13350	COG1024	Enoyl-CoA hydratase
K9C16_RS13355	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS13365	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS13390	COG2186	Transcriptional regulator
K9C16_RS13395	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS13405	COG4948	Mandelate Racemase Muconate Lactonizing
K9C16_RS13410	COG2271	Major facilitator Superfamily
K9C16_RS13415	COG2721	sulfolactate sulfo-lyase activity
K9C16_RS13420	COG0697	spore germination
K9C16_RS13455	COG1113	amino acid transport
K9C16_RS13475	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS13495	COG0531	amino acid
K9C16_RS13505	COG1113	amino acid transport
K9C16_RS13540	COG3209	COG3209 Rhs family protein
K9C16_RS13560	COG4269	membrane
K9C16_RS13575	COG1902	pentaerythritol trinitrate reductase activity
K9C16_RS13575	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9C16_RS13585	COG5001	Diguanylate cyclase
K9C16_RS13585	COG4251	negative regulation of phosphorylation
K9C16_RS13585	COG2203	Gaf domain
K9C16_RS13585	COG3706	GGDEF domain
K9C16_RS13595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K9C16_RS13615	COG4172	Belongs to the ABC transporter superfamily
K9C16_RS13620	COG4239	(ABC) transporter, permease
K9C16_RS13625	COG4174	ABC transporter (Permease)
K9C16_RS13635	COG0741	lytic transglycosylase activity
K9C16_RS13635	COG1388	LysM domain
K9C16_RS13635	COG0741	lytic transglycosylase activity
K9C16_RS13635	COG1388	LysM domain
K9C16_RS13640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K9C16_RS13680	COG0583	DNA-binding transcription factor activity
K9C16_RS13685	COG1279	arginine transmembrane transporter activity
K9C16_RS13705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9C16_RS13710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9C16_RS13715	COG0006	proline dipeptidase activity
K9C16_RS13835	COG1196	nuclear chromosome segregation
K9C16_RS13835	COG0741	lytic transglycosylase activity
K9C16_RS13835	COG0739	heme binding
K9C16_RS14100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K9C16_RS14120	COG3384	dioxygenase
K9C16_RS14130	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
K9C16_RS14135	COG2878	Part of a membrane complex involved in electron transport
K9C16_RS14140	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K9C16_RS14165	COG0768	penicillin binding
K9C16_RS14170	COG0742	ribosomal rna small subunit methyltransferase
K9C16_RS14185	COG0830	nickel cation binding
K9C16_RS14195	COG0804	urea catabolic process
K9C16_RS14235	COG1253	flavin adenine dinucleotide binding
K9C16_RS14240	COG2851	Citrate transporter
K9C16_RS14290	COG1773	rubredoxin
K9C16_RS14295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9C16_RS14305	COG0583	DNA-binding transcription factor activity
K9C16_RS14335	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
K9C16_RS14340	COG4181	ATPase activity
K9C16_RS14385	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9C16_RS14405	COG0306	phosphate transporter
K9C16_RS14415	COG3958	Transketolase
K9C16_RS14420	COG3959	Transketolase, thiamine diphosphate binding domain
K9C16_RS14425	COG2271	Major facilitator Superfamily
K9C16_RS14430	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS14435	COG0583	DNA-binding transcription factor activity
K9C16_RS14450	COG2223	nitrite transmembrane transporter activity
K9C16_RS14455	COG2207	Transcriptional regulator
K9C16_RS14460	COG2066	Belongs to the glutaminase family
K9C16_RS14465	COG0242	peptide deformylase activity
K9C16_RS14470	COG0477	Major facilitator Superfamily
K9C16_RS14480	COG0028	Belongs to the TPP enzyme family
K9C16_RS14485	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS14495	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS14500	COG2267	carboxylic ester hydrolase activity
K9C16_RS14510	COG2271	Major facilitator Superfamily
K9C16_RS14525	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS14545	COG1414	Transcriptional regulator
K9C16_RS14560	COG1024	Enoyl-CoA hydratase
K9C16_RS14570	COG1215	transferase activity, transferring glycosyl groups
K9C16_RS14575	COG1649	PFAM Uncharacterised BCR, COG1649
K9C16_RS14575	COG0726	polysaccharide deacetylase
K9C16_RS14585	COG4681	YaeQ
K9C16_RS14595	COG0523	cobalamin synthesis protein
K9C16_RS14605	COG1607	acyl-coa hydrolase
K9C16_RS14615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9C16_RS14620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
K9C16_RS14625	COG1309	transcriptional regulator
K9C16_RS14650	COG2040	homocysteine
K9C16_RS14655	COG0531	amino acid
K9C16_RS14680	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9C16_RS14685	COG0477	Major facilitator Superfamily
K9C16_RS14745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K9C16_RS14820	COG0582	viral genome integration into host DNA
K9C16_RS14830	COG0405	Gamma-glutamyltransferase
K9C16_RS14835	COG2814	Major facilitator Superfamily
K9C16_RS14845	COG2050	protein possibly involved in aromatic compounds catabolism
K9C16_RS14860	COG1090	epimerase
K9C16_RS14880	COG0420	3'-5' exonuclease activity
K9C16_RS14905	COG0735	belongs to the Fur family
K9C16_RS14910	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9C16_RS14930	COG0121	glutamine amidotransferase
K9C16_RS14945	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9C16_RS14955	COG0210	DNA helicase
K9C16_RS14960	COG2885	chlorophyll binding
K9C16_RS14965	COG0204	Acyl-transferase
K9C16_RS14980	COG2894	cell division
K9C16_RS15000	COG1280	lysine exporter protein (LysE YggA)
K9C16_RS15005	COG1674	ftsk spoiiie
K9C16_RS15010	COG0492	ferredoxin-NADP+ reductase activity
K9C16_RS15015	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
K9C16_RS15025	COG0456	acetyltransferase
K9C16_RS15070	COG1981	membrane
K9C16_RS15085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9C16_RS15085	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
K9C16_RS15105	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS15115	COG0657	acetylesterase activity
K9C16_RS15125	COG0473	3-isopropylmalate dehydrogenase activity
K9C16_RS15130	COG0583	DNA-binding transcription factor activity
K9C16_RS15150	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9C16_RS15175	COG0564	pseudouridine synthase activity
K9C16_RS15185	COG0358	DNA primase activity
K9C16_RS15200	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
K9C16_RS15230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K9C16_RS15260	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
K9C16_RS15270	COG0351	phosphomethylpyrimidine kinase
K9C16_RS15270	COG0352	thiamine-phosphate diphosphorylase activity
K9C16_RS15270	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K9C16_RS15275	COG1652	LysM domain
K9C16_RS15300	COG1399	metal-binding, possibly nucleic acid-binding protein
K9C16_RS15305	COG3101	peptidyl-lysine hydroxylation
K9C16_RS15310	COG0009	L-threonylcarbamoyladenylate synthase
K9C16_RS15315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K9C16_RS15320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K9C16_RS15335	COG4106	trans-aconitate 2-methyltransferase activity
K9C16_RS15350	COG0596	Alpha beta hydrolase
K9C16_RS15350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9C16_RS15350	COG2226	methyltransferase
K9C16_RS15355	COG1877	trehalose-phosphatase activity
K9C16_RS15360	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
K9C16_RS15365	COG2223	nitrite transmembrane transporter activity
K9C16_RS15385	COG1196	nuclear chromosome segregation
K9C16_RS15395	COG0730	response to heat
K9C16_RS15410	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K9C16_RS15420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9C16_RS15470	COG0489	protein tyrosine kinase activity
K9C16_RS15480	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9C16_RS15480	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9C16_RS15510	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K9C16_RS15515	COG2081	HI0933 family
K9C16_RS15525	COG0668	transmembrane transport
K9C16_RS15545	COG0583	DNA-binding transcription factor activity
K9C16_RS15565	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9C16_RS15570	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K9C16_RS15600	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K9C16_RS15625	COG3706	GGDEF domain
K9C16_RS15640	COG0745	RESPONSE REGULATOR receiver
K9C16_RS15660	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K9C16_RS15700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9C16_RS15715	COG0583	DNA-binding transcription factor activity
K9C16_RS15725	COG0583	DNA-binding transcription factor activity
K9C16_RS15740	COG0583	DNA-binding transcription factor activity
K9C16_RS15745	COG1053	succinate dehydrogenase
K9C16_RS15760	COG1309	transcriptional regulator
K9C16_RS15765	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9C16_RS15770	COG2814	Major facilitator Superfamily
K9C16_RS15775	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS15780	COG0583	DNA-binding transcription factor activity
K9C16_RS15785	COG1063	alcohol dehydrogenase
K9C16_RS15815	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
K9C16_RS15820	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K9C16_RS15825	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K9C16_RS15845	COG2132	Multicopper oxidase
K9C16_RS15855	COG0561	phosphatase activity
K9C16_RS15860	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
K9C16_RS15885	COG1214	PFAM Peptidase M22, glycoprotease
K9C16_RS15925	COG3293	Transposase
K9C16_RS15940	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K9C16_RS15950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K9C16_RS15955	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K9C16_RS15960	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K9C16_RS16020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9C16_RS16030	COG1846	Transcriptional regulator
K9C16_RS16035	COG1764	response to oxidative stress
K9C16_RS16060	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9C16_RS16060	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9C16_RS16075	COG0037	tRNA processing
K9C16_RS16085	COG0248	Ppx GppA phosphatase
K9C16_RS16115	COG0072	phenylalanine-tRNA ligase activity
K9C16_RS16160	COG1238	metal cluster binding
K9C16_RS16165	COG0625	glutathione transferase activity
K9C16_RS16180	COG0318	PFAM AMP-dependent synthetase and ligase
K9C16_RS16185	COG3028	Belongs to the UPF0307 family
K9C16_RS16190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9C16_RS16210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K9C16_RS16215	COG0617	tRNA 3'-terminal CCA addition
K9C16_RS16220	COG1555	photosystem II stabilization
K9C16_RS16225	COG3956	TIGRFAM MazG family protein
K9C16_RS16235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
K9C16_RS16255	COG0784	Response regulator, receiver
K9C16_RS16255	COG2205	protein histidine kinase activity
K9C16_RS16255	COG5002	protein histidine kinase activity
K9C16_RS16260	COG1024	Enoyl-CoA hydratase
K9C16_RS16265	COG2084	Dehydrogenase
K9C16_RS16270	COG3622	Belongs to the hyi family
K9C16_RS16300	COG0697	spore germination
K9C16_RS16310	COG2814	Major facilitator Superfamily
K9C16_RS16320	COG2072	flavoprotein involved in K transport
K9C16_RS16325	COG0492	ferredoxin-NADP+ reductase activity
K9C16_RS16330	COG0431	NADPH-dependent FMN reductase
K9C16_RS16335	COG0798	PFAM Bile acid sodium symporter
K9C16_RS16345	COG0640	Transcriptional regulator
K9C16_RS16390	COG2132	Multicopper oxidase
K9C16_RS16405	COG2205	protein histidine kinase activity
K9C16_RS16490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9C16_RS16500	COG0583	DNA-binding transcription factor activity
K9C16_RS16510	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
K9C16_RS16520	COG0084	hydrolase, TatD family'
K9C16_RS16535	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
K9C16_RS16565	COG0440	acetolactate synthase activity
K9C16_RS16570	COG0028	Belongs to the TPP enzyme family
K9C16_RS16595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9C16_RS16600	COG1136	(ABC) transporter
K9C16_RS16600	COG0577	efflux transmembrane transporter activity
K9C16_RS16605	COG1538	Outer membrane efflux protein
K9C16_RS16620	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
K9C16_RS16625	COG1162	GTPase activity
K9C16_RS16635	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K9C16_RS16675	COG1426	Protein conserved in bacteria
K9C16_RS16710	COG0793	Belongs to the peptidase S41A family
K9C16_RS16735	COG1012	belongs to the aldehyde dehydrogenase family
K9C16_RS16740	COG3265	gluconokinase activity
K9C16_RS16750	COG0800	Aldolase
K9C16_RS16760	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K9C16_RS16765	COG0857	belongs to the CobB CobQ family
K9C16_RS16765	COG0280	phosphate acetyltransferase
K9C16_RS16770	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
K9C16_RS16770	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
K9C16_RS16790	COG0740	serine-type endopeptidase activity
K9C16_RS16800	COG4774	siderophore transport
K9C16_RS16810	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K9C16_RS16820	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9C16_RS16820	COG2813	Specifically methylates the guanine in position
K9C16_RS16920	COG0788	formyltetrahydrofolate deformylase activity
K9C16_RS16945	COG4651	solute:proton antiporter activity
K9C16_RS16945	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K9C16_RS16965	COG0724	RNA recognition motif
K9C16_RS16970	COG0210	DNA helicase
K9C16_RS16995	COG1733	regulation of RNA biosynthetic process
K9C16_RS17005	COG2900	Belongs to the SlyX family
K9C16_RS17010	COG0488	(ABC) transporter
K9C16_RS17015	COG1280	lysine exporter protein (LysE YggA)
K9C16_RS17020	COG1560	Kdo2-lipid A biosynthetic process
K9C16_RS17030	COG1301	dicarboxylic acid transport
K9C16_RS17055	COG0252	asparaginase activity
K9C16_RS17085	COG0473	3-isopropylmalate dehydrogenase activity
K9C16_RS17140	COG0583	DNA-binding transcription factor activity
K9C16_RS17150	COG0625	glutathione transferase activity
K9C16_RS17155	COG2378	regulation of single-species biofilm formation
K9C16_RS17160	COG0546	phosphoglycolate phosphatase activity
K9C16_RS17170	COG1530	ribonuclease E activity
K9C16_RS17175	COG0318	PFAM AMP-dependent synthetase and ligase
K9C16_RS17190	COG0583	DNA-binding transcription factor activity
K9C16_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS17200	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K9C16_RS17210	COG0534	Mate efflux family protein
K9C16_RS17225	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K9C16_RS17255	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
K9C16_RS17255	COG0493	'glutamate synthase
K9C16_RS17265	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K9C16_RS17270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9C16_RS17285	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K9C16_RS17295	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
K9C16_RS17295	COG0644	oxidoreductase
K9C16_RS17305	COG0425	Belongs to the sulfur carrier protein TusA family
K9C16_RS17310	COG4535	Mg2 and Co2 transporter CorC
K9C16_RS17320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9C16_RS17340	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
K9C16_RS17345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
K9C16_RS17345	COG0475	glutathione-regulated potassium exporter activity
K9C16_RS17360	COG0484	heat shock protein binding
K9C16_RS17365	COG0789	Transcriptional regulator
K9C16_RS17370	COG0598	Magnesium transport protein CorA
K9C16_RS17385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
K9C16_RS17390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9C16_RS17395	COG1074	ATP-dependent DNA helicase activity
K9C16_RS17400	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
K9C16_RS17420	COG2226	methyltransferase
K9C16_RS17430	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K9C16_RS17445	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K9C16_RS17460	COG2111	Na H antiporter
K9C16_RS17460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K9C16_RS17465	COG1006	Multisubunit Na H antiporter MnhC subunit
K9C16_RS17470	COG0651	ATP synthesis coupled electron transport
K9C16_RS17475	COG1863	multisubunit Na H antiporter MnhE subunit
K9C16_RS17480	COG2212	antiporter activity
K9C16_RS17485	COG1320	monovalent cation:proton antiporter activity
K9C16_RS17500	COG0195	Participates in both transcription termination and antitermination
K9C16_RS17555	COG0237	dephospho-CoA kinase activity
K9C16_RS17565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9C16_RS17580	COG0497	DNA recombination
K9C16_RS17590	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K9C16_RS17620	COG2169	Transcriptional regulator
K9C16_RS17620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
K9C16_RS17625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K9C16_RS17680	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
K9C16_RS17695	COG0326	Molecular chaperone. Has ATPase activity
K9C16_RS17710	COG2056	Na+-H+ antiporter family
K9C16_RS17810	COG0546	phosphoglycolate phosphatase activity
K9C16_RS17815	COG1716	ATPase activity
K9C16_RS17860	COG0181	hydroxymethylbilane synthase activity
K9C16_RS17870	COG3275	phosphorelay sensor kinase activity
K9C16_RS17895	COG0697	spore germination
K9C16_RS17920	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
K9C16_RS17925	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
K9C16_RS17930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9C16_RS17935	COG0772	Belongs to the SEDS family
K9C16_RS17960	COG4974	Belongs to the 'phage' integrase family
K9C16_RS17965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9C16_RS17975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
K9C16_RS17985	COG2197	response regulator
K9C16_RS18000	COG0793	Belongs to the peptidase S41A family
K9C16_RS18005	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
K9C16_RS18010	COG0795	lipopolysaccharide-transporting ATPase activity
K9C16_RS18050	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9C16_RS18050	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9C16_RS18060	COG0004	ammonium transporteR
K9C16_RS18065	COG0347	Belongs to the P(II) protein family
K9C16_RS18085	COG0659	secondary active sulfate transmembrane transporter activity
K9C16_RS18090	COG0589	response to stress
K9C16_RS18145	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9C16_RS18165	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K9C16_RS18180	COG0318	PFAM AMP-dependent synthetase and ligase
K9C16_RS18190	COG0477	Major facilitator Superfamily
K9C16_RS18195	COG2860	membrane
K9C16_RS18205	COG1253	flavin adenine dinucleotide binding
K9C16_RS18215	COG0477	Major facilitator Superfamily
K9C16_RS18225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K9C16_RS18265	COG0655	NAD(P)H dehydrogenase (quinone) activity
K9C16_RS18275	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
K9C16_RS18345	COG0758	DNA mediated transformation
K9C16_RS18355	COG0697	spore germination
K9C16_RS18360	COG1309	transcriptional regulator
K9C16_RS18375	COG0386	Belongs to the glutathione peroxidase family
K9C16_RS18440	COG1121	(ABC) transporter
K9C16_RS18445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K9C16_RS18450	COG1280	lysine exporter protein (LysE YggA)
K9C16_RS18455	COG2837	iron assimilation
K9C16_RS18460	COG0281	malic enzyme
K9C16_RS18505	COG0519	Catalyzes the synthesis of GMP from XMP
K9C16_RS18505	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K9C16_RS18510	COG4399	Belongs to the UPF0754 family
K9C16_RS18515	COG2259	Doxx family
K9C16_RS18520	COG0586	Pfam SNARE associated Golgi protein
K9C16_RS18535	COG1192	Involved in chromosome partitioning
K9C16_RS18545	COG0271	Belongs to the BolA IbaG family
K9C16_RS18585	COG3321	synthase
K9C16_RS18585	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
K9C16_RS18585	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K9C16_RS18585	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K9C16_RS18590	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS18600	COG2197	response regulator
K9C16_RS18610	COG3916	Acyl-homoserine-lactone synthase
K9C16_RS18615	COG0477	Major facilitator Superfamily
K9C16_RS18620	COG1024	Enoyl-CoA hydratase
K9C16_RS18625	COG1024	Enoyl-CoA hydratase
K9C16_RS18630	COG1960	acyl-CoA dehydrogenase activity
K9C16_RS18635	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9C16_RS18655	COG1113	amino acid transport
K9C16_RS18660	COG1113	amino acid transport
K9C16_RS18665	COG0251	oxidation-reduction process
K9C16_RS18705	COG0564	pseudouridine synthase activity
K9C16_RS18750	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K9C16_RS18765	COG1802	Transcriptional regulator
K9C16_RS18775	COG1448	Aminotransferase
K9C16_RS18780	COG0277	FAD linked oxidase domain protein
K9C16_RS18790	COG2186	Transcriptional regulator
K9C16_RS18800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9C16_RS18805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
K9C16_RS18820	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K9C16_RS18825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K9C16_RS18835	COG1215	transferase activity, transferring glycosyl groups
K9C16_RS18840	COG0438	transferase activity, transferring glycosyl groups
K9C16_RS18855	COG5039	Polysaccharide pyruvyl transferase
K9C16_RS18865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K9C16_RS18895	COG0728	peptidoglycan biosynthetic process
K9C16_RS18900	COG3023	N-Acetylmuramoyl-L-alanine amidase
K9C16_RS18960	COG0546	phosphoglycolate phosphatase activity
K9C16_RS18965	COG1028	Short-chain dehydrogenase reductase Sdr
K9C16_RS18985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9C16_RS18990	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9C16_RS18995	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9C16_RS19000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9C16_RS19005	COG1116	anion transmembrane transporter activity
K9C16_RS19010	COG1309	transcriptional regulator
K9C16_RS19015	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
K9C16_RS19025	COG0196	riboflavin kinase activity
K9C16_RS19030	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K9C16_RS19040	COG1047	Peptidyl-prolyl cis-trans
K9C16_RS19080	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
K9C16_RS19085	COG0657	acetylesterase activity
K9C16_RS19105	COG0583	DNA-binding transcription factor activity
K9C16_RS19135	COG2951	lytic endotransglycosylase activity
K9C16_RS19140	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K9C16_RS19155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K9C16_RS19165	COG0671	phosphoesterase, PA-phosphatase related
K9C16_RS19170	COG0861	Integral membrane protein TerC family
K9C16_RS19180	COG0754	glutathionylspermidine amidase activity
K9C16_RS19190	COG0402	S-adenosylhomocysteine deaminase activity
K9C16_RS19205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9C16_RS19210	COG1230	cation diffusion facilitator family transporter
K9C16_RS19225	COG0706	membrane insertase activity