locus-tag	class	description
AN415_RS00005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AN415_RS00010	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AN415_RS00015	COG0596	Alpha beta hydrolase
AN415_RS00045	COG0488	(ABC) transporter
AN415_RS00050	COG0586	Pfam SNARE associated Golgi protein
AN415_RS00060	COG0187	DNA topoisomerase II activity
AN415_RS00070	COG0592	DNA-directed DNA polymerase activity
AN415_RS00095	COG0706	membrane insertase activity
AN415_RS00110	COG1230	cation diffusion facilitator family transporter
AN415_RS00115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN415_RS00135	COG0402	S-adenosylhomocysteine deaminase activity
AN415_RS00145	COG0754	glutathionylspermidine amidase activity
AN415_RS00155	COG0861	Integral membrane protein TerC family
AN415_RS00160	COG0671	phosphoesterase, PA-phosphatase related
AN415_RS00170	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AN415_RS00185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AN415_RS00190	COG2951	lytic endotransglycosylase activity
AN415_RS00230	COG0583	DNA-binding transcription factor activity
AN415_RS00250	COG0657	acetylesterase activity
AN415_RS00255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AN415_RS00295	COG0733	neurotransmitter:sodium symporter activity
AN415_RS00330	COG0583	DNA-binding transcription factor activity
AN415_RS00335	COG2233	PERMEase
AN415_RS00350	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN415_RS00385	COG2814	Major facilitator Superfamily
AN415_RS00390	COG0656	L-ascorbic acid biosynthetic process
AN415_RS00395	COG0583	DNA-binding transcription factor activity
AN415_RS00405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN415_RS00410	COG1064	alcohol dehydrogenase
AN415_RS00415	COG2818	Glycosylase
AN415_RS00430	COG1194	a g-specific adenine glycosylase
AN415_RS00450	COG2983	Belongs to the UPF0260 family
AN415_RS00455	COG2133	pyrroloquinoline quinone binding
AN415_RS00460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AN415_RS00465	COG2116	formate transmembrane transporter activity
AN415_RS00485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN415_RS00490	COG1335	isochorismatase
AN415_RS00495	COG0385	Bile acid
AN415_RS00500	COG0534	Mate efflux family protein
AN415_RS00505	COG1683	Conserved Protein
AN415_RS00525	COG0625	glutathione transferase activity
AN415_RS00535	COG1113	amino acid transport
AN415_RS00545	COG0523	cobalamin synthesis protein
AN415_RS00555	COG2188	Transcriptional regulator
AN415_RS00585	COG0010	Belongs to the arginase family
AN415_RS00600	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AN415_RS00630	COG0084	hydrolase, TatD family'
AN415_RS00655	COG1169	isochorismate synthase
AN415_RS00660	COG3433	isochorismatase activity
AN415_RS00660	COG1535	isochorismatase
AN415_RS00665	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS00670	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN415_RS00675	COG2226	methyltransferase
AN415_RS00675	COG3433	isochorismatase activity
AN415_RS00675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN415_RS00680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN415_RS00685	COG1021	2,3-dihydroxybenzoate-AMP ligase
AN415_RS00690	COG3486	L-lysine 6-monooxygenase (NADPH) activity
AN415_RS00695	COG0019	diaminopimelate decarboxylase activity
AN415_RS00720	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AN415_RS00725	COG4774	siderophore transport
AN415_RS00740	COG0534	Mate efflux family protein
AN415_RS00750	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN415_RS00825	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AN415_RS00835	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AN415_RS00840	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AN415_RS00925	COG0534	Mate efflux family protein
AN415_RS00930	COG0436	Aminotransferase
AN415_RS00935	COG2733	membrane
AN415_RS00950	COG2918	glutathione biosynthetic process
AN415_RS00965	COG5632	N-Acetylmuramoyl-L-alanine amidase
AN415_RS00965	COG3409	Peptidoglycan-binding domain 1 protein
AN415_RS00965	COG1388	LysM domain
AN415_RS00995	COG3150	esterase
AN415_RS01005	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AN415_RS01015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN415_RS01025	COG2233	PERMEase
AN415_RS01030	COG2351	hydroxyisourate hydrolase activity
AN415_RS01065	COG3706	GGDEF domain
AN415_RS01080	COG1393	Belongs to the ArsC family
AN415_RS01085	COG0708	Exodeoxyribonuclease III
AN415_RS01105	COG0189	ligase activity
AN415_RS01125	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AN415_RS01135	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AN415_RS01150	COG4942	peptidase
AN415_RS01160	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN415_RS01170	COG2119	membrane
AN415_RS01175	COG4774	siderophore transport
AN415_RS01180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN415_RS01180	COG0426	domain, Protein
AN415_RS01205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AN415_RS01225	COG1902	pentaerythritol trinitrate reductase activity
AN415_RS01230	COG1519	Transferase
AN415_RS01235	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AN415_RS01240	COG0668	transmembrane transport
AN415_RS01250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN415_RS01255	COG1335	isochorismatase
AN415_RS01260	COG1522	sequence-specific DNA binding
AN415_RS01285	COG2205	protein histidine kinase activity
AN415_RS01285	COG0784	Response regulator, receiver
AN415_RS01285	COG2198	Histidine kinase
AN415_RS01290	COG3162	membrane
AN415_RS01295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN415_RS01305	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN415_RS01320	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AN415_RS01325	COG1309	transcriptional regulator
AN415_RS01345	COG0352	thiamine-phosphate diphosphorylase activity
AN415_RS01345	COG0351	phosphomethylpyrimidine kinase
AN415_RS01345	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AN415_RS01355	COG2814	Major facilitator Superfamily
AN415_RS01370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AN415_RS01380	COG1113	amino acid transport
AN415_RS01390	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN415_RS01395	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS01405	COG1335	isochorismatase
AN415_RS01435	COG2814	Major facilitator Superfamily
AN415_RS01440	COG0583	DNA-binding transcription factor activity
AN415_RS01460	COG0667	Aldo Keto reductase
AN415_RS01480	COG1733	regulation of RNA biosynthetic process
AN415_RS01495	COG1733	regulation of RNA biosynthetic process
AN415_RS01500	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN415_RS01510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AN415_RS01565	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AN415_RS01605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AN415_RS01635	COG0427	acetyl-CoA hydrolase
AN415_RS01655	COG0659	secondary active sulfate transmembrane transporter activity
AN415_RS01660	COG4221	oxidoreductase activity
AN415_RS01665	COG2873	o-acetylhomoserine
AN415_RS01670	COG0488	(ABC) transporter
AN415_RS01735	COG0833	amino acid
AN415_RS01780	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AN415_RS01785	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AN415_RS01800	COG2226	methyltransferase
AN415_RS01850	COG0070	glutamate synthase
AN415_RS01850	COG0067	glutamate synthase
AN415_RS01850	COG0069	glutamate synthase activity
AN415_RS01855	COG0493	'glutamate synthase
AN415_RS01865	COG1704	LemA family
AN415_RS01870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AN415_RS01905	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN415_RS01915	COG0194	GDP metabolic process
AN415_RS01965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AN415_RS01985	COG5380	lipid catabolic process
AN415_RS01990	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AN415_RS02015	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AN415_RS02020	COG0277	FAD linked oxidase domain protein
AN415_RS02030	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AN415_RS02035	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN415_RS02050	COG1289	transmembrane transporter activity
AN415_RS02060	COG0628	permease
AN415_RS02065	COG1192	Involved in chromosome partitioning
AN415_RS02095	COG0833	amino acid
AN415_RS02100	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN415_RS02105	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN415_RS02115	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS02155	COG0583	DNA-binding transcription factor activity
AN415_RS02215	COG0583	DNA-binding transcription factor activity
AN415_RS02265	COG0517	IMP dehydrogenase activity
AN415_RS02270	COG1983	PspC domain protein
AN415_RS02280	COG1960	acyl-CoA dehydrogenase activity
AN415_RS02295	COG0408	coproporphyrinogen oxidase activity
AN415_RS02315	COG0513	Belongs to the DEAD box helicase family
AN415_RS02325	COG1127	ABC transporter
AN415_RS02330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AN415_RS02340	COG2854	intermembrane phospholipid transfer
AN415_RS02350	COG0598	Magnesium transport protein CorA
AN415_RS02360	COG0494	nUDIX hydrolase
AN415_RS02365	COG1040	competence protein
AN415_RS02370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AN415_RS02390	COG1946	Acyl-CoA thioesterase
AN415_RS02395	COG1301	dicarboxylic acid transport
AN415_RS02410	COG1959	2 iron, 2 sulfur cluster binding
AN415_RS02415	COG1017	nitric oxide dioxygenase activity
AN415_RS02415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN415_RS02420	COG0433	COG0433 Predicted ATPase
AN415_RS02425	COG0626	cystathionine gamma-synthase activity
AN415_RS02580	COG1960	acyl-CoA dehydrogenase activity
AN415_RS02585	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AN415_RS02615	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AN415_RS02620	COG0339	signal peptide processing
AN415_RS02625	COG0557	exoribonuclease II activity
AN415_RS02670	COG0179	Fumarylacetoacetate (FAA) hydrolase
AN415_RS02675	COG2169	Transcriptional regulator
AN415_RS02680	COG0697	spore germination
AN415_RS02685	COG1295	ribonuclease BN
AN415_RS02720	COG1702	phosphate starvation-inducible protein PhoH
AN415_RS02730	COG0739	heme binding
AN415_RS02730	COG0741	lytic transglycosylase activity
AN415_RS02730	COG1196	nuclear chromosome segregation
AN415_RS02760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AN415_RS02765	COG1183	phosphatidylcholine synthase activity
AN415_RS02810	COG1960	acyl-CoA dehydrogenase activity
AN415_RS02825	COG1960	acyl-CoA dehydrogenase activity
AN415_RS02830	COG1309	transcriptional regulator
AN415_RS02845	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AN415_RS02850	COG1960	acyl-CoA dehydrogenase activity
AN415_RS02870	COG2969	positive regulation of protein catabolic process
AN415_RS02880	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AN415_RS02895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AN415_RS02900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AN415_RS02920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AN415_RS02930	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN415_RS02935	COG1408	metallophosphoesterase
AN415_RS02945	COG2199	diguanylate cyclase activity
AN415_RS03005	COG1607	acyl-coa hydrolase
AN415_RS03035	COG2350	Protein conserved in bacteria
AN415_RS03045	COG0613	PHP domain protein
AN415_RS03050	COG3781	membrane
AN415_RS03060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AN415_RS03075	COG1862	Preprotein translocase
AN415_RS03105	COG2205	protein histidine kinase activity
AN415_RS03110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AN415_RS03130	COG0726	polysaccharide deacetylase
AN415_RS03135	COG0463	Glycosyl transferase, family 2
AN415_RS03140	COG0438	transferase activity, transferring glycosyl groups
AN415_RS03155	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AN415_RS03205	COG1960	acyl-CoA dehydrogenase activity
AN415_RS03210	COG1960	acyl-CoA dehydrogenase activity
AN415_RS03220	COG2205	protein histidine kinase activity
AN415_RS03225	COG0745	RESPONSE REGULATOR receiver
AN415_RS03230	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AN415_RS03250	COG2096	Adenosyltransferase
AN415_RS03300	COG0285	dihydrofolate synthase activity
AN415_RS03320	COG0450	alkyl hydroperoxide reductase
AN415_RS03335	COG0477	Major facilitator Superfamily
AN415_RS03340	COG1272	protein, Hemolysin III
AN415_RS03350	COG2153	protein acetylation
AN415_RS03370	COG0183	Belongs to the thiolase family
AN415_RS03375	COG2207	Transcriptional regulator
AN415_RS03395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN415_RS03415	COG0183	Belongs to the thiolase family
AN415_RS03425	COG2885	chlorophyll binding
AN415_RS03425	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AN415_RS03435	COG1690	Belongs to the RtcB family
AN415_RS03440	COG0833	amino acid
AN415_RS03450	COG2233	PERMEase
AN415_RS03455	COG1217	gtp-binding protein TYPA
AN415_RS03480	COG2094	Belongs to the DNA glycosylase MPG family
AN415_RS03485	COG4772	TonB-dependent receptor
AN415_RS03490	COG1902	pentaerythritol trinitrate reductase activity
AN415_RS03495	COG0679	Auxin Efflux Carrier
AN415_RS03505	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN415_RS03510	COG0354	folic acid binding
AN415_RS03520	COG3189	MarR family transcriptional regulator
AN415_RS03525	COG2824	Alkylphosphonate utilization operon protein PhnA
AN415_RS03530	COG3422	double-strand break repair
AN415_RS03570	COG0840	transmembrane signaling receptor activity
AN415_RS03585	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN415_RS03600	COG5510	response to toxic substance
AN415_RS03610	COG2832	Protein of unknown function (DUF454)
AN415_RS03615	COG1376	ErfK ybiS ycfS ynhG family protein
AN415_RS03655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AN415_RS03665	COG1289	transmembrane transporter activity
AN415_RS03670	COG2814	Major facilitator Superfamily
AN415_RS03685	COG1115	amino acid carrier protein
AN415_RS03690	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN415_RS03695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AN415_RS03700	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AN415_RS03725	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN415_RS03735	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AN415_RS03740	COG1077	Cell shape determining protein MreB Mrl
AN415_RS03745	COG1792	Involved in formation and maintenance of cell shape
AN415_RS03750	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AN415_RS03755	COG0424	maF-like protein
AN415_RS03760	COG1530	ribonuclease E activity
AN415_RS03770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN415_RS03780	COG0560	Phosphoserine phosphatase
AN415_RS03790	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN415_RS03815	COG2207	Transcriptional regulator
AN415_RS03880	COG4197	protein conserved in bacteria, prophage-related
AN415_RS03910	COG0305	Participates in initiation and elongation during chromosome replication
AN415_RS03940	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
AN415_RS03995	COG1802	Transcriptional regulator
AN415_RS03995	COG4626	Terminase
AN415_RS04000	COG4695	Portal protein
AN415_RS04005	COG0740	serine-type endopeptidase activity
AN415_RS04110	COG1113	amino acid transport
AN415_RS04115	COG2828	Protein conserved in bacteria
AN415_RS04120	COG0142	geranyltranstransferase activity
AN415_RS04125	COG2315	Protein conserved in bacteria
AN415_RS04140	COG1752	Esterase of the alpha-beta hydrolase superfamily
AN415_RS04160	COG2194	sulfuric ester hydrolase activity
AN415_RS04165	COG0745	RESPONSE REGULATOR receiver
AN415_RS04170	COG0642	Histidine kinase
AN415_RS04180	COG0004	ammonium transporteR
AN415_RS04185	COG0583	DNA-binding transcription factor activity
AN415_RS04205	COG0525	valine-tRNA ligase activity
AN415_RS04215	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS04225	COG0393	Putative heavy-metal-binding
AN415_RS04230	COG0393	Putative heavy-metal-binding
AN415_RS04235	COG1538	Outer membrane efflux protein
AN415_RS04245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN415_RS04250	COG0671	phosphoesterase, PA-phosphatase related
AN415_RS04280	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AN415_RS04295	COG1648	precorrin-2 dehydrogenase activity
AN415_RS04295	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AN415_RS04300	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AN415_RS04305	COG1733	regulation of RNA biosynthetic process
AN415_RS04315	COG0531	amino acid
AN415_RS04330	COG0321	lipoyl(octanoyl) transferase activity
AN415_RS04335	COG2921	Belongs to the UPF0250 family
AN415_RS04370	COG2009	succinate dehydrogenase
AN415_RS04375	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AN415_RS04380	COG1053	succinate dehydrogenase
AN415_RS04385	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AN415_RS04400	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN415_RS04430	COG2354	Protein conserved in bacteria
AN415_RS04435	COG2321	neutral zinc metallopeptidase
AN415_RS04460	COG2843	Capsule synthesis protein
AN415_RS04475	COG0589	response to stress
AN415_RS04495	COG0505	Belongs to the CarA family
AN415_RS04520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN415_RS04525	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AN415_RS04575	COG0477	Major facilitator Superfamily
AN415_RS04580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AN415_RS04595	COG1597	lipid kinase activity
AN415_RS04600	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AN415_RS04625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN415_RS04630	COG0584	glycerophosphoryl diester phosphodiesterase
AN415_RS04650	COG0741	lytic transglycosylase activity
AN415_RS04670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AN415_RS04685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN415_RS04720	COG0778	Nitroreductase
AN415_RS04745	COG1929	Belongs to the glycerate kinase type-1 family
AN415_RS04750	COG0243	molybdopterin cofactor binding
AN415_RS04755	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AN415_RS04760	COG3339	Conserved Protein
AN415_RS04770	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AN415_RS04785	COG1113	amino acid transport
AN415_RS04795	COG0019	diaminopimelate decarboxylase activity
AN415_RS04805	COG2267	carboxylic ester hydrolase activity
AN415_RS04810	COG1280	lysine exporter protein (LysE YggA)
AN415_RS04815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AN415_RS04845	COG0463	Glycosyl transferase, family 2
AN415_RS04865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN415_RS04905	COG4591	ABC-type transport system involved in lipoprotein release permease component
AN415_RS04910	COG1136	(ABC) transporter
AN415_RS04915	COG2333	competence protein COMEC
AN415_RS04915	COG0658	competence protein
AN415_RS04925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AN415_RS04925	COG0616	signal peptide processing
AN415_RS04930	COG0596	Alpha beta hydrolase
AN415_RS04935	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AN415_RS04945	COG0628	permease
AN415_RS04980	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN415_RS05000	COG0823	Involved in the tonB-independent uptake of proteins
AN415_RS05020	COG0824	Thioesterase
AN415_RS05025	COG1473	amidohydrolase
AN415_RS05045	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AN415_RS05045	COG0047	phosphoribosylformylglycinamidine synthase activity
AN415_RS05050	COG2814	Major facilitator Superfamily
AN415_RS05065	COG1024	Enoyl-CoA hydratase
AN415_RS05070	COG1056	cytidyltransferase-related domain
AN415_RS05070	COG1051	belongs to the nudix hydrolase family
AN415_RS05080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AN415_RS05095	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AN415_RS05110	COG4625	pathogenesis
AN415_RS05115	COG0583	DNA-binding transcription factor activity
AN415_RS05120	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AN415_RS05125	COG4208	sulfate ABC transporter
AN415_RS05130	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AN415_RS05140	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AN415_RS05145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AN415_RS05150	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AN415_RS05170	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN415_RS05185	COG0681	Belongs to the peptidase S26 family
AN415_RS05200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AN415_RS05210	COG1381	Involved in DNA repair and RecF pathway recombination
AN415_RS05215	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AN415_RS05225	COG4221	oxidoreductase activity
AN415_RS05250	COG0436	Aminotransferase
AN415_RS05270	COG0556	nucleotide-excision repair
AN415_RS05325	COG2070	2-Nitropropane dioxygenase
AN415_RS05355	COG1215	transferase activity, transferring glycosyl groups
AN415_RS05370	COG0415	Belongs to the DNA photolyase family
AN415_RS05380	COG1252	NADH dehydrogenase
AN415_RS05385	COG1686	Belongs to the peptidase S11 family
AN415_RS05400	COG1187	pseudouridine synthase activity
AN415_RS05420	COG0477	Major facilitator Superfamily
AN415_RS05425	COG0583	DNA-binding transcription factor activity
AN415_RS05430	COG1823	symporter activity
AN415_RS05440	COG0612	Peptidase, M16
AN415_RS05470	COG1203	CRISPR-associated helicase, Cas3
AN415_RS05495	COG0352	thiamine-phosphate diphosphorylase activity
AN415_RS05530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN415_RS05545	COG1309	transcriptional regulator
AN415_RS05555	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AN415_RS05560	COG0076	glutamate decarboxylase activity
AN415_RS05570	COG1522	sequence-specific DNA binding
AN415_RS05575	COG3961	Belongs to the TPP enzyme family
AN415_RS05580	COG1113	amino acid transport
AN415_RS05585	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AN415_RS05590	COG0573	inorganic phosphate transmembrane transporter activity
AN415_RS05600	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AN415_RS05605	COG0616	signal peptide processing
AN415_RS05640	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AN415_RS05645	COG1686	Belongs to the peptidase S11 family
AN415_RS05670	COG0583	DNA-binding transcription factor activity
AN415_RS05675	COG1067	ATP-dependent peptidase activity
AN415_RS05700	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AN415_RS05720	COG1966	Carbon starvation protein
AN415_RS05725	COG2879	small protein
AN415_RS05840	COG4626	Terminase
AN415_RS05840	COG1802	Transcriptional regulator
AN415_RS05845	COG4695	Portal protein
AN415_RS05955	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN415_RS05965	COG0582	viral genome integration into host DNA
AN415_RS05970	COG1196	nuclear chromosome segregation
AN415_RS06035	COG1741	Belongs to the pirin family
AN415_RS06045	COG2964	Protein conserved in bacteria
AN415_RS06060	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN415_RS06065	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AN415_RS06070	COG4605	iron ion homeostasis
AN415_RS06075	COG4604	ABC transporter, ATP-binding protein
AN415_RS06080	COG4607	ABC-type enterochelin transport system periplasmic component
AN415_RS06085	COG4774	siderophore transport
AN415_RS06095	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AN415_RS06100	COG1021	2,3-dihydroxybenzoate-AMP ligase
AN415_RS06105	COG3433	isochorismatase activity
AN415_RS06105	COG1535	isochorismatase
AN415_RS06120	COG1132	(ABC) transporter
AN415_RS06125	COG1132	(ABC) transporter
AN415_RS06130	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AN415_RS06140	COG1169	isochorismate synthase
AN415_RS06155	COG3739	integral membrane protein
AN415_RS06185	COG0302	gtp cyclohydrolase
AN415_RS06195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AN415_RS06225	COG0308	aminopeptidase N
AN415_RS06230	COG0512	Glutamine amidotransferase of anthranilate synthase
AN415_RS06245	COG0174	glutamine synthetase
AN415_RS06255	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AN415_RS06290	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AN415_RS06295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AN415_RS06300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AN415_RS06320	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AN415_RS06325	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AN415_RS06330	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AN415_RS06345	COG1960	acyl-CoA dehydrogenase activity
AN415_RS06350	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AN415_RS06355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN415_RS06370	COG2223	nitrite transmembrane transporter activity
AN415_RS06380	COG0024	Methionine aminopeptidase
AN415_RS06385	COG0052	Belongs to the universal ribosomal protein uS2 family
AN415_RS06400	COG2207	Transcriptional regulator
AN415_RS06425	COG2951	lytic endotransglycosylase activity
AN415_RS06430	COG0772	Belongs to the SEDS family
AN415_RS06445	COG0842	Transport permease protein
AN415_RS06450	COG1131	(ABC) transporter
AN415_RS06490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN415_RS06505	COG4215	(ABC) transporter
AN415_RS06510	COG4160	amino acid transport
AN415_RS06515	COG4598	ABC transporter
AN415_RS06525	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AN415_RS06530	COG0826	peptidase U32
AN415_RS06535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN415_RS06550	COG1720	tRNA m6t6A37 methyltransferase activity
AN415_RS06560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AN415_RS06575	COG0642	Histidine kinase
AN415_RS06585	COG0494	nUDIX hydrolase
AN415_RS06595	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AN415_RS06600	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AN415_RS06605	COG3139	Protein of unknown function (DUF1315)
AN415_RS06615	COG1301	dicarboxylic acid transport
AN415_RS06620	COG1960	acyl-CoA dehydrogenase activity
AN415_RS06625	COG2819	hydrolase of the alpha beta superfamily
AN415_RS06635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AN415_RS06645	COG2195	Cleaves the N-terminal amino acid of tripeptides
AN415_RS06650	COG1234	tRNA 3'-trailer cleavage
AN415_RS06675	COG2363	Small membrane protein
AN415_RS06695	COG0513	Belongs to the DEAD box helicase family
AN415_RS06705	COG0778	Nitroreductase
AN415_RS06735	COG1286	toxin biosynthetic process
AN415_RS06760	COG4783	chaperone-mediated protein folding
AN415_RS06765	COG1610	YqeY-like protein
AN415_RS06865	COG3111	PFAM Bacterial OB fold (BOF) protein
AN415_RS06890	COG3243	poly(R)-hydroxyalkanoic acid synthase
AN415_RS06895	COG0786	glutamate:sodium symporter activity
AN415_RS06905	COG0583	DNA-binding transcription factor activity
AN415_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS06930	COG2186	Transcriptional regulator
AN415_RS06990	COG0477	Major facilitator Superfamily
AN415_RS07015	COG2995	paraquat-inducible protein a
AN415_RS07020	COG3008	intermembrane lipid transfer
AN415_RS07020	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AN415_RS07030	COG2351	hydroxyisourate hydrolase activity
AN415_RS07070	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AN415_RS07080	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AN415_RS07085	COG0642	Histidine kinase
AN415_RS07090	COG0745	RESPONSE REGULATOR receiver
AN415_RS07110	COG1794	racemase activity, acting on amino acids and derivatives
AN415_RS07140	COG1301	dicarboxylic acid transport
AN415_RS07150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN415_RS07155	COG2011	ABC-type metal ion transport system permease component
AN415_RS07160	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AN415_RS07165	COG1464	Belongs to the NlpA lipoprotein family
AN415_RS07170	COG0151	Belongs to the GarS family
AN415_RS07175	COG0138	bifunctional purine biosynthesis protein purh
AN415_RS07180	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AN415_RS07210	COG2308	Evidence 4 Homologs of previously reported genes of
AN415_RS07220	COG1305	Transglutaminase-like
AN415_RS07230	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AN415_RS07235	COG0305	Participates in initiation and elongation during chromosome replication
AN415_RS07260	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AN415_RS07270	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AN415_RS07275	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AN415_RS07300	COG1649	PFAM Uncharacterised BCR, COG1649
AN415_RS07300	COG0726	polysaccharide deacetylase
AN415_RS07305	COG1215	transferase activity, transferring glycosyl groups
AN415_RS07310	COG3658	cytochrome
AN415_RS07320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN415_RS07345	COG0583	DNA-binding transcription factor activity
AN415_RS07365	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN415_RS07370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN415_RS07385	COG1960	acyl-CoA dehydrogenase activity
AN415_RS07390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN415_RS07395	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN415_RS07420	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AN415_RS07425	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AN415_RS07435	COG2205	protein histidine kinase activity
AN415_RS07440	COG0745	RESPONSE REGULATOR receiver
AN415_RS07445	COG0174	glutamine synthetase
AN415_RS07465	COG0729	surface antigen
AN415_RS07490	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN415_RS07495	COG2814	Major facilitator Superfamily
AN415_RS07510	COG0583	DNA-binding transcription factor activity
AN415_RS07590	COG3409	Peptidoglycan-binding domain 1 protein
AN415_RS07590	COG3267	Type II secretory pathway component ExeA
AN415_RS07615	COG0681	Belongs to the peptidase S26 family
AN415_RS07650	COG4373	Mu-like prophage FluMu protein gp28
AN415_RS07665	COG4383	Mu-like prophage protein gp29
AN415_RS07670	COG2369	cell adhesion
AN415_RS07675	COG5005	Phage virion morphogenesis
AN415_RS07690	COG4397	Mu-like prophage major head subunit gpT
AN415_RS07780	COG1187	pseudouridine synthase activity
AN415_RS07800	COG0802	atpase or kinase
AN415_RS07805	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AN415_RS07815	COG1923	regulation of RNA biosynthetic process
AN415_RS07820	COG0697	spore germination
AN415_RS07840	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN415_RS07845	COG0519	Catalyzes the synthesis of GMP from XMP
AN415_RS07845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AN415_RS07850	COG4302	ethanolamine ammonia-lyase activity
AN415_RS07855	COG4303	Ethanolamine ammonia lyase large subunit
AN415_RS07860	COG0531	amino acid
AN415_RS07880	COG1454	alcohol dehydrogenase
AN415_RS07885	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AN415_RS07910	COG0308	aminopeptidase N
AN415_RS07950	COG1605	Chorismate mutase
AN415_RS07970	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AN415_RS07995	COG1309	transcriptional regulator
AN415_RS08005	COG0668	transmembrane transport
AN415_RS08035	COG4773	Receptor
AN415_RS08055	COG0488	(ABC) transporter
AN415_RS08060	COG0589	response to stress
AN415_RS08080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AN415_RS08090	COG3135	benzoate transporter
AN415_RS08095	COG1522	sequence-specific DNA binding
AN415_RS08105	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AN415_RS08110	COG0583	DNA-binding transcription factor activity
AN415_RS08120	COG0183	Belongs to the thiolase family
AN415_RS08130	COG2030	dehydratase
AN415_RS08135	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN415_RS08150	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AN415_RS08160	COG0824	Thioesterase
AN415_RS08165	COG1454	alcohol dehydrogenase
AN415_RS08175	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AN415_RS08195	COG0069	glutamate synthase activity
AN415_RS08215	COG2814	Major facilitator Superfamily
AN415_RS08230	COG0511	ligase activity, forming carbon-carbon bonds
AN415_RS08245	COG1116	anion transmembrane transporter activity
AN415_RS08245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN415_RS08250	COG0745	RESPONSE REGULATOR receiver
AN415_RS08260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN415_RS08260	COG2146	nitrite reductase [NAD(P)H] activity
AN415_RS08265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN415_RS08270	COG0243	molybdopterin cofactor binding
AN415_RS08280	COG0243	molybdopterin cofactor binding
AN415_RS08285	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AN415_RS08300	COG0521	Mo-molybdopterin cofactor biosynthetic process
AN415_RS08300	COG0315	cyclic pyranopterin monophosphate synthase activity
AN415_RS08305	COG0303	'Molybdopterin
AN415_RS08320	COG0697	spore germination
AN415_RS08340	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AN415_RS08345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AN415_RS08400	COG2204	response regulator
AN415_RS08405	COG3852	Histidine kinase
AN415_RS08425	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AN415_RS08430	COG0575	Belongs to the CDS family
AN415_RS08465	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN415_RS08480	COG2137	regulation of response to DNA damage stimulus
AN415_RS08490	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AN415_RS08495	COG1011	Hydrolase
AN415_RS08520	COG1522	sequence-specific DNA binding
AN415_RS08530	COG1113	amino acid transport
AN415_RS08545	COG0659	secondary active sulfate transmembrane transporter activity
AN415_RS08550	COG2135	peptidase activity
AN415_RS08565	COG5001	Diguanylate cyclase
AN415_RS08565	COG3300	MHYT domain
AN415_RS08585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN415_RS08585	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AN415_RS08585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AN415_RS08590	COG1105	Belongs to the carbohydrate kinase PfkB family
AN415_RS08595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN415_RS08595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AN415_RS08625	COG0024	Methionine aminopeptidase
AN415_RS08630	COG0583	DNA-binding transcription factor activity
AN415_RS08640	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AN415_RS08645	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AN415_RS08650	COG0516	GMP reductase activity
AN415_RS08650	COG0517	IMP dehydrogenase activity
AN415_RS08675	COG0552	protein localization to endoplasmic reticulum
AN415_RS08685	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AN415_RS08695	COG4890	Cyd operon protein YbgT
AN415_RS08700	COG1294	oxidase, subunit
AN415_RS08715	COG1585	Membrane protein implicated in regulation of membrane protease activity
AN415_RS08725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AN415_RS08730	COG4774	siderophore transport
AN415_RS08745	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AN415_RS08750	COG0569	domain protein
AN415_RS08755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AN415_RS08785	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AN415_RS08790	COG0542	response to heat
AN415_RS08815	COG1902	pentaerythritol trinitrate reductase activity
AN415_RS08815	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN415_RS08860	COG2323	membrane
AN415_RS08865	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AN415_RS08875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN415_RS08880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN415_RS08885	COG0183	Belongs to the thiolase family
AN415_RS08890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AN415_RS08895	COG0596	Alpha beta hydrolase
AN415_RS08900	COG2271	Major facilitator Superfamily
AN415_RS08905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN415_RS08910	COG3485	protocatechuate 3,4-dioxygenase
AN415_RS08915	COG3485	protocatechuate 3,4-dioxygenase
AN415_RS08920	COG0710	3-dehydroquinate dehydratase activity
AN415_RS08925	COG3420	alginic acid biosynthetic process
AN415_RS08930	COG3659	wide pore channel activity
AN415_RS08935	COG4993	Dehydrogenase
AN415_RS08945	COG2391	methyltransferase activity
AN415_RS08960	COG1414	Transcriptional regulator
AN415_RS08965	COG0583	DNA-binding transcription factor activity
AN415_RS08970	COG1960	acyl-CoA dehydrogenase activity
AN415_RS08995	COG2814	Major facilitator Superfamily
AN415_RS09005	COG0154	amidase activity
AN415_RS09025	COG4638	Rieske (2fe-2S)
AN415_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS09045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN415_RS09055	COG3733	amine oxidase
AN415_RS09065	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS09085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AN415_RS09090	COG0183	Belongs to the thiolase family
AN415_RS09095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN415_RS09100	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN415_RS09110	COG4829	muconolactone delta-isomerase
AN415_RS09115	COG4948	Mandelate Racemase Muconate Lactonizing
AN415_RS09120	COG0583	DNA-binding transcription factor activity
AN415_RS09130	COG2186	Transcriptional regulator
AN415_RS09150	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS09165	COG1902	pentaerythritol trinitrate reductase activity
AN415_RS09165	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN415_RS09205	COG1309	transcriptional regulator
AN415_RS09220	COG4689	acetoacetate decarboxylase
AN415_RS09235	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AN415_RS09245	COG2084	Dehydrogenase
AN415_RS09250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AN415_RS09310	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AN415_RS09325	COG0556	nucleotide-excision repair
AN415_RS09355	COG1073	alpha beta
AN415_RS09365	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS09380	COG2207	Transcriptional regulator
AN415_RS09390	COG2205	protein histidine kinase activity
AN415_RS09395	COG0745	RESPONSE REGULATOR receiver
AN415_RS09410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN415_RS09420	COG1538	Outer membrane efflux protein
AN415_RS09430	COG2072	flavoprotein involved in K transport
AN415_RS09440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN415_RS09640	COG3539	Fimbrial protein
AN415_RS09665	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AN415_RS09675	COG0753	catalase activity
AN415_RS09690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AN415_RS09750	COG1535	isochorismatase
AN415_RS09750	COG3433	isochorismatase activity
AN415_RS09755	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS09760	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AN415_RS09765	COG4149	molybdate abc transporter
AN415_RS09770	COG0725	ABC transporter, periplasmic molybdate-binding protein
AN415_RS09780	COG4638	Rieske (2fe-2S)
AN415_RS09785	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AN415_RS09790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN415_RS09790	COG0543	2 iron, 2 sulfur cluster binding
AN415_RS09805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN415_RS09815	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS09830	COG2207	Transcriptional regulator
AN415_RS09835	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS09840	COG2610	gluconate transmembrane transporter activity
AN415_RS09850	COG0583	DNA-binding transcription factor activity
AN415_RS09865	COG2031	fatty acid transporter
AN415_RS09870	COG0183	Belongs to the thiolase family
AN415_RS09875	COG0583	DNA-binding transcription factor activity
AN415_RS09880	COG0583	DNA-binding transcription factor activity
AN415_RS09895	COG1027	Aspartate ammonia-lyase
AN415_RS09905	COG0477	Major facilitator Superfamily
AN415_RS09925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN415_RS09930	COG4521	taurine ABC transporter
AN415_RS09945	COG2188	Transcriptional regulator
AN415_RS09955	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AN415_RS09960	COG1733	regulation of RNA biosynthetic process
AN415_RS09965	COG3708	Transcriptional regulator
AN415_RS09965	COG2207	Transcriptional regulator
AN415_RS09980	COG0730	response to heat
AN415_RS10000	COG3781	membrane
AN415_RS10005	COG1063	alcohol dehydrogenase
AN415_RS10015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AN415_RS10020	COG0508	dehydrogenase complex catalyzes the overall conversion of
AN415_RS10025	COG0022	dehydrogenase e1 component
AN415_RS10030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AN415_RS10035	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AN415_RS10050	COG3706	GGDEF domain
AN415_RS10065	COG0133	tryptophan synthase activity
AN415_RS10075	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AN415_RS10110	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AN415_RS10135	COG2226	methyltransferase
AN415_RS10190	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AN415_RS10195	COG4773	Receptor
AN415_RS10215	COG0730	response to heat
AN415_RS10220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AN415_RS10235	COG0406	alpha-ribazole phosphatase activity
AN415_RS10240	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AN415_RS10255	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN415_RS10285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AN415_RS10295	COG4264	IucA IucC family
AN415_RS10300	COG4264	IucA IucC family
AN415_RS10320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AN415_RS10335	COG1960	acyl-CoA dehydrogenase activity
AN415_RS10340	COG1960	acyl-CoA dehydrogenase activity
AN415_RS10345	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN415_RS10350	COG2207	Transcriptional regulator
AN415_RS10355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN415_RS10360	COG0776	regulation of translation
AN415_RS10385	COG0822	iron-sulfur transferase activity
AN415_RS10390	COG0316	Belongs to the HesB IscA family
AN415_RS10420	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AN415_RS10440	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AN415_RS10445	COG0702	epimerase
AN415_RS10480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AN415_RS10490	COG0339	signal peptide processing
AN415_RS10535	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AN415_RS10540	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AN415_RS10570	COG0776	regulation of translation
AN415_RS10635	COG0084	hydrolase, TatD family'
AN415_RS10655	COG1663	tetraacyldisaccharide 4'-kinase activity
AN415_RS10660	COG1132	(ABC) transporter
AN415_RS10670	COG0811	peptide transport
AN415_RS10675	COG1475	DNA binding
AN415_RS10680	COG1192	Involved in chromosome partitioning
AN415_RS10690	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AN415_RS10705	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AN415_RS10710	COG0191	fructose-bisphosphate aldolase activity
AN415_RS10730	COG0424	maF-like protein
AN415_RS10735	COG2850	peptidyl-arginine hydroxylation
AN415_RS10745	COG0640	Transcriptional regulator
AN415_RS10755	COG3619	membrane
AN415_RS10760	COG3122	Protein conserved in bacteria
AN415_RS10765	COG1132	(ABC) transporter
AN415_RS10785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AN415_RS10790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AN415_RS10800	COG0506	proline dehydrogenase activity
AN415_RS10800	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AN415_RS10800	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AN415_RS10805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AN415_RS10820	COG3698	Phosphodiester glycosidase
AN415_RS10830	COG2353	YceI-like domain
AN415_RS10840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AN415_RS10885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AN415_RS10885	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AN415_RS10910	COG3539	Fimbrial protein
AN415_RS10915	COG3121	Chaperone
AN415_RS10940	COG0697	spore germination
AN415_RS10950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AN415_RS10960	COG0583	DNA-binding transcription factor activity
AN415_RS10980	COG1309	transcriptional regulator
AN415_RS10995	COG1522	sequence-specific DNA binding
AN415_RS11005	COG1126	abc transporter atp-binding protein
AN415_RS11010	COG0765	amino acid transport
AN415_RS11015	COG0765	amino acid transport
AN415_RS11045	COG1464	Belongs to the NlpA lipoprotein family
AN415_RS11055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AN415_RS11060	COG2011	ABC-type metal ion transport system permease component
AN415_RS11065	COG0012	GTP binding
AN415_RS11090	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AN415_RS11130	COG0386	Belongs to the glutathione peroxidase family
AN415_RS11140	COG0436	Aminotransferase
AN415_RS11145	COG1301	dicarboxylic acid transport
AN415_RS11180	COG3634	alkyl hydroperoxide reductase activity
AN415_RS11195	COG0583	DNA-binding transcription factor activity
AN415_RS11200	COG0798	PFAM Bile acid sodium symporter
AN415_RS11205	COG0640	Transcriptional regulator
AN415_RS11220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AN415_RS11230	COG0583	DNA-binding transcription factor activity
AN415_RS11240	COG1953	Uracil, thiamine, allantoin
AN415_RS11250	COG2175	clavaminate synthase activity
AN415_RS11255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN415_RS11260	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AN415_RS11265	COG4521	taurine ABC transporter
AN415_RS11275	COG0477	Major facilitator Superfamily
AN415_RS11305	COG1271	oxidase subunit
AN415_RS11310	COG1294	oxidase, subunit
AN415_RS11320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN415_RS11340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AN415_RS11360	COG3052	prosthetic group binding
AN415_RS11365	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AN415_RS11375	COG2814	Major facilitator Superfamily
AN415_RS11390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN415_RS11395	COG1346	cytolysis
AN415_RS11405	COG0583	DNA-binding transcription factor activity
AN415_RS11410	COG0625	glutathione transferase activity
AN415_RS11415	COG0625	glutathione transferase activity
AN415_RS11420	COG0583	DNA-binding transcription factor activity
AN415_RS11435	COG1045	serine acetyltransferase
AN415_RS11440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AN415_RS11445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AN415_RS11450	COG1280	lysine exporter protein (LysE YggA)
AN415_RS11460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN415_RS11465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN415_RS11470	COG1126	abc transporter atp-binding protein
AN415_RS11475	COG0765	amino acid transport
AN415_RS11480	COG0765	amino acid transport
AN415_RS11495	COG0784	Response regulator, receiver
AN415_RS11495	COG2205	protein histidine kinase activity
AN415_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS11585	COG0583	DNA-binding transcription factor activity
AN415_RS11605	COG0318	PFAM AMP-dependent synthetase and ligase
AN415_RS11610	COG1309	transcriptional regulator
AN415_RS11615	COG1960	acyl-CoA dehydrogenase activity
AN415_RS11620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AN415_RS11625	COG1024	Enoyl-CoA hydratase
AN415_RS11630	COG4770	biotin carboxylase activity
AN415_RS11640	COG0583	DNA-binding transcription factor activity
AN415_RS11655	COG1960	acyl-CoA dehydrogenase activity
AN415_RS11665	COG2814	Major facilitator Superfamily
AN415_RS11675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AN415_RS11680	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AN415_RS11685	COG2814	Major facilitator Superfamily
AN415_RS11690	COG1960	acyl-CoA dehydrogenase activity
AN415_RS11695	COG1024	Enoyl-CoA hydratase
AN415_RS11700	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS11705	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN415_RS11710	COG0183	Belongs to the thiolase family
AN415_RS11720	COG2814	Major facilitator Superfamily
AN415_RS11730	COG1024	Enoyl-CoA hydratase
AN415_RS11740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AN415_RS11745	COG1960	acyl-CoA dehydrogenase activity
AN415_RS11750	COG2814	Major facilitator Superfamily
AN415_RS11755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AN415_RS11760	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AN415_RS11775	COG3842	ATPase activity
AN415_RS11780	COG1840	ABC-type Fe3 transport system, periplasmic component
AN415_RS11790	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN415_RS11795	COG1414	Transcriptional regulator
AN415_RS11805	COG0583	DNA-binding transcription factor activity
AN415_RS11810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AN415_RS11815	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS11825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AN415_RS11830	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS11835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN415_RS11840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN415_RS11845	COG2267	carboxylic ester hydrolase activity
AN415_RS11865	COG3038	cytochrome b561
AN415_RS11870	COG0753	catalase activity
AN415_RS11880	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN415_RS11885	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AN415_RS11910	COG1278	Cold shock
AN415_RS11970	COG2050	protein possibly involved in aromatic compounds catabolism
AN415_RS11980	COG3327	negative regulation of DNA-templated transcription, initiation
AN415_RS11985	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AN415_RS11990	COG0183	Belongs to the thiolase family
AN415_RS11995	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN415_RS12000	COG1024	Enoyl-CoA hydratase
AN415_RS12005	COG1024	Enoyl-CoA hydratase
AN415_RS12010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN415_RS12015	COG2151	metal-sulfur cluster biosynthetic enzyme
AN415_RS12020	COG3396	Phenylacetate-CoA oxygenase
AN415_RS12025	COG3460	Phenylacetate-CoA oxygenase
AN415_RS12030	COG3396	Phenylacetate-CoA oxygenase
AN415_RS12035	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS12035	COG2030	dehydratase
AN415_RS12040	COG1760	l-serine dehydratase
AN415_RS12045	COG0531	amino acid
AN415_RS12050	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS12075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AN415_RS12095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN415_RS12105	COG0789	Transcriptional regulator
AN415_RS12115	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AN415_RS12140	COG2807	transmembrane transport
AN415_RS12145	COG0590	tRNA wobble adenosine to inosine editing
AN415_RS12270	COG1116	anion transmembrane transporter activity
AN415_RS12275	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AN415_RS12285	COG0864	Transcriptional regulator
AN415_RS12295	COG1733	regulation of RNA biosynthetic process
AN415_RS12300	COG2249	NAD(P)H dehydrogenase (quinone) activity
AN415_RS12305	COG0439	Biotin carboxylase
AN415_RS12320	COG1063	alcohol dehydrogenase
AN415_RS12330	COG1309	transcriptional regulator
AN415_RS12355	COG0038	chloride channel
AN415_RS12360	COG4770	biotin carboxylase activity
AN415_RS12380	COG1914	H( )-stimulated, divalent metal cation uptake system
AN415_RS12385	COG0583	DNA-binding transcription factor activity
AN415_RS12405	COG3209	COG3209 Rhs family protein
AN415_RS12445	COG1250	3-hydroxyacyl-CoA dehydrogenase
AN415_RS12465	COG2814	Major facilitator Superfamily
AN415_RS12475	COG1560	Kdo2-lipid A biosynthetic process
AN415_RS12485	COG5006	permease, DMT superfamily
AN415_RS12490	COG1522	sequence-specific DNA binding
AN415_RS12505	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AN415_RS12515	COG4122	O-methyltransferase activity
AN415_RS12545	COG1538	Outer membrane efflux protein
AN415_RS12550	COG1137	ATPase activity
AN415_RS12555	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AN415_RS12565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AN415_RS12645	COG2814	Major facilitator Superfamily
AN415_RS12675	COG1278	Cold shock
AN415_RS12680	COG1280	lysine exporter protein (LysE YggA)
AN415_RS12715	COG1570	exodeoxyribonuclease VII activity
AN415_RS12765	COG0583	DNA-binding transcription factor activity
AN415_RS12770	COG4638	Rieske (2fe-2S)
AN415_RS12775	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AN415_RS12780	COG0543	2 iron, 2 sulfur cluster binding
AN415_RS12780	COG0633	Ferredoxin
AN415_RS12785	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS12790	COG3135	benzoate transporter
AN415_RS12810	COG1643	Atp-dependent helicase
AN415_RS12815	COG0450	alkyl hydroperoxide reductase
AN415_RS12825	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AN415_RS12835	COG3634	alkyl hydroperoxide reductase activity
AN415_RS12855	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AN415_RS12860	COG0625	glutathione transferase activity
AN415_RS12870	COG2885	chlorophyll binding
AN415_RS12905	COG0542	response to heat
AN415_RS12920	COG1765	OsmC-like protein
AN415_RS12930	COG0667	Aldo Keto reductase
AN415_RS12945	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AN415_RS12955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AN415_RS12965	COG0527	aspartate kinase activity
AN415_RS12975	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AN415_RS12985	COG3038	cytochrome b561
AN415_RS12990	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AN415_RS12995	COG2252	PERMEase
AN415_RS13005	COG2072	flavoprotein involved in K transport
AN415_RS13020	COG1741	Belongs to the pirin family
AN415_RS13025	COG1309	transcriptional regulator
AN415_RS13035	COG0300	oxidoreductase activity
AN415_RS13040	COG2072	flavoprotein involved in K transport
AN415_RS13045	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AN415_RS13090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AN415_RS13105	COG2814	Major facilitator Superfamily
AN415_RS13110	COG1024	Enoyl-CoA hydratase
AN415_RS13125	COG1024	Enoyl-CoA hydratase
AN415_RS13130	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS13140	COG1960	acyl-CoA dehydrogenase activity
AN415_RS13165	COG2186	Transcriptional regulator
AN415_RS13170	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS13180	COG4948	Mandelate Racemase Muconate Lactonizing
AN415_RS13185	COG2271	Major facilitator Superfamily
AN415_RS13190	COG2721	sulfolactate sulfo-lyase activity
AN415_RS13195	COG0697	spore germination
AN415_RS13225	COG1113	amino acid transport
AN415_RS13245	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS13265	COG0531	amino acid
AN415_RS13275	COG1113	amino acid transport
AN415_RS13315	COG3209	COG3209 Rhs family protein
AN415_RS13350	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN415_RS13350	COG1902	pentaerythritol trinitrate reductase activity
AN415_RS13360	COG2203	Gaf domain
AN415_RS13360	COG5001	Diguanylate cyclase
AN415_RS13360	COG4251	negative regulation of phosphorylation
AN415_RS13360	COG3706	GGDEF domain
AN415_RS13370	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN415_RS13420	COG4172	Belongs to the ABC transporter superfamily
AN415_RS13425	COG4239	(ABC) transporter, permease
AN415_RS13430	COG4174	ABC transporter (Permease)
AN415_RS13440	COG1388	LysM domain
AN415_RS13440	COG0741	lytic transglycosylase activity
AN415_RS13440	COG0741	lytic transglycosylase activity
AN415_RS13440	COG1388	LysM domain
AN415_RS13445	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN415_RS13485	COG0583	DNA-binding transcription factor activity
AN415_RS13490	COG1279	arginine transmembrane transporter activity
AN415_RS13510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN415_RS13515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN415_RS13520	COG0006	proline dipeptidase activity
AN415_RS13555	COG2194	sulfuric ester hydrolase activity
AN415_RS13610	COG0739	heme binding
AN415_RS13915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AN415_RS13940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AN415_RS13945	COG2878	Part of a membrane complex involved in electron transport
AN415_RS13950	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AN415_RS13970	COG0768	penicillin binding
AN415_RS13975	COG0742	ribosomal rna small subunit methyltransferase
AN415_RS13990	COG0830	nickel cation binding
AN415_RS14000	COG0804	urea catabolic process
AN415_RS14040	COG1253	flavin adenine dinucleotide binding
AN415_RS14045	COG2851	Citrate transporter
AN415_RS14090	COG1773	rubredoxin
AN415_RS14095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AN415_RS14105	COG0583	DNA-binding transcription factor activity
AN415_RS14130	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AN415_RS14135	COG4181	ATPase activity
AN415_RS14180	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AN415_RS14200	COG0306	phosphate transporter
AN415_RS14210	COG3958	Transketolase
AN415_RS14215	COG3959	Transketolase, thiamine diphosphate binding domain
AN415_RS14220	COG2271	Major facilitator Superfamily
AN415_RS14225	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS14230	COG0583	DNA-binding transcription factor activity
AN415_RS14245	COG2223	nitrite transmembrane transporter activity
AN415_RS14250	COG2207	Transcriptional regulator
AN415_RS14255	COG2066	Belongs to the glutaminase family
AN415_RS14260	COG0242	peptide deformylase activity
AN415_RS14265	COG0477	Major facilitator Superfamily
AN415_RS14275	COG0028	Belongs to the TPP enzyme family
AN415_RS14290	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS14295	COG2267	carboxylic ester hydrolase activity
AN415_RS14305	COG2271	Major facilitator Superfamily
AN415_RS14310	COG0446	pyridine nucleotide-disulphide oxidoreductase
AN415_RS14320	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS14340	COG1414	Transcriptional regulator
AN415_RS14355	COG1024	Enoyl-CoA hydratase
AN415_RS14365	COG1215	transferase activity, transferring glycosyl groups
AN415_RS14370	COG0726	polysaccharide deacetylase
AN415_RS14370	COG1649	PFAM Uncharacterised BCR, COG1649
AN415_RS14380	COG4681	YaeQ
AN415_RS14390	COG0523	cobalamin synthesis protein
AN415_RS14400	COG1607	acyl-coa hydrolase
AN415_RS14410	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN415_RS14415	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AN415_RS14420	COG1309	transcriptional regulator
AN415_RS14445	COG2040	homocysteine
AN415_RS14450	COG0531	amino acid
AN415_RS14475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN415_RS14480	COG0477	Major facilitator Superfamily
AN415_RS14500	COG0084	hydrolase, TatD family'
AN415_RS14555	COG0629	single-stranded DNA binding
AN415_RS14600	COG0582	viral genome integration into host DNA
AN415_RS14620	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN415_RS14700	COG0592	DNA-directed DNA polymerase activity
AN415_RS14950	COG1484	DNA-dependent DNA replication
AN415_RS15030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AN415_RS15070	COG0405	Gamma-glutamyltransferase
AN415_RS15075	COG2814	Major facilitator Superfamily
AN415_RS15085	COG2050	protein possibly involved in aromatic compounds catabolism
AN415_RS15100	COG1090	epimerase
AN415_RS15120	COG0420	3'-5' exonuclease activity
AN415_RS15145	COG0735	belongs to the Fur family
AN415_RS15150	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AN415_RS15170	COG0121	glutamine amidotransferase
AN415_RS15185	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN415_RS15195	COG0210	DNA helicase
AN415_RS15200	COG2885	chlorophyll binding
AN415_RS15205	COG0204	Acyl-transferase
AN415_RS15220	COG2894	cell division
AN415_RS15235	COG1280	lysine exporter protein (LysE YggA)
AN415_RS15240	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AN415_RS15240	COG1674	ftsk spoiiie
AN415_RS15245	COG0492	ferredoxin-NADP+ reductase activity
AN415_RS15250	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AN415_RS15260	COG0456	acetyltransferase
AN415_RS15305	COG1981	membrane
AN415_RS15320	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AN415_RS15320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN415_RS15340	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS15350	COG0657	acetylesterase activity
AN415_RS15360	COG0473	3-isopropylmalate dehydrogenase activity
AN415_RS15365	COG0583	DNA-binding transcription factor activity
AN415_RS15385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AN415_RS15410	COG0564	pseudouridine synthase activity
AN415_RS15420	COG0358	DNA primase activity
AN415_RS15435	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AN415_RS15465	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AN415_RS15495	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AN415_RS15505	COG0352	thiamine-phosphate diphosphorylase activity
AN415_RS15505	COG0351	phosphomethylpyrimidine kinase
AN415_RS15505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AN415_RS15510	COG1652	LysM domain
AN415_RS15535	COG1399	metal-binding, possibly nucleic acid-binding protein
AN415_RS15540	COG3101	peptidyl-lysine hydroxylation
AN415_RS15545	COG0009	L-threonylcarbamoyladenylate synthase
AN415_RS15550	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AN415_RS15555	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AN415_RS15570	COG4106	trans-aconitate 2-methyltransferase activity
AN415_RS15585	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AN415_RS15585	COG0596	Alpha beta hydrolase
AN415_RS15585	COG2226	methyltransferase
AN415_RS15590	COG1877	trehalose-phosphatase activity
AN415_RS15595	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AN415_RS15600	COG2223	nitrite transmembrane transporter activity
AN415_RS15620	COG1196	nuclear chromosome segregation
AN415_RS15630	COG0730	response to heat
AN415_RS15645	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AN415_RS15655	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN415_RS15705	COG0489	protein tyrosine kinase activity
AN415_RS15715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN415_RS15715	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN415_RS15745	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AN415_RS15750	COG2081	HI0933 family
AN415_RS15760	COG0668	transmembrane transport
AN415_RS15780	COG0583	DNA-binding transcription factor activity
AN415_RS15805	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AN415_RS15810	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN415_RS15840	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AN415_RS15880	COG0745	RESPONSE REGULATOR receiver
AN415_RS15900	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AN415_RS15910	COG0384	phenazine biosynthesis protein PhzF
AN415_RS15940	COG1309	transcriptional regulator
AN415_RS15945	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AN415_RS15960	COG0583	DNA-binding transcription factor activity
AN415_RS15990	COG0583	DNA-binding transcription factor activity
AN415_RS16005	COG0583	DNA-binding transcription factor activity
AN415_RS16010	COG1053	succinate dehydrogenase
AN415_RS16020	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AN415_RS16025	COG2814	Major facilitator Superfamily
AN415_RS16030	COG1960	acyl-CoA dehydrogenase activity
AN415_RS16035	COG0583	DNA-binding transcription factor activity
AN415_RS16040	COG1063	alcohol dehydrogenase
AN415_RS16070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AN415_RS16075	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AN415_RS16080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN415_RS16100	COG2132	Multicopper oxidase
AN415_RS16110	COG0561	phosphatase activity
AN415_RS16125	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AN415_RS16150	COG1214	PFAM Peptidase M22, glycoprotease
AN415_RS16200	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AN415_RS16210	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AN415_RS16215	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AN415_RS16220	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AN415_RS16280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AN415_RS16290	COG1846	Transcriptional regulator
AN415_RS16295	COG1764	response to oxidative stress
AN415_RS16335	COG0037	tRNA processing
AN415_RS16345	COG0248	Ppx GppA phosphatase
AN415_RS16370	COG0072	phenylalanine-tRNA ligase activity
AN415_RS16405	COG1238	metal cluster binding
AN415_RS16410	COG0625	glutathione transferase activity
AN415_RS16425	COG0318	PFAM AMP-dependent synthetase and ligase
AN415_RS16430	COG3028	Belongs to the UPF0307 family
AN415_RS16435	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AN415_RS16455	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AN415_RS16460	COG0617	tRNA 3'-terminal CCA addition
AN415_RS16465	COG1555	photosystem II stabilization
AN415_RS16470	COG3956	TIGRFAM MazG family protein
AN415_RS16480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AN415_RS16500	COG5002	protein histidine kinase activity
AN415_RS16500	COG0784	Response regulator, receiver
AN415_RS16500	COG2205	protein histidine kinase activity
AN415_RS16505	COG1024	Enoyl-CoA hydratase
AN415_RS16510	COG2084	Dehydrogenase
AN415_RS16515	COG3622	Belongs to the hyi family
AN415_RS16545	COG0697	spore germination
AN415_RS16555	COG2814	Major facilitator Superfamily
AN415_RS16580	COG2072	flavoprotein involved in K transport
AN415_RS16585	COG0492	ferredoxin-NADP+ reductase activity
AN415_RS16590	COG0431	NADPH-dependent FMN reductase
AN415_RS16595	COG0798	PFAM Bile acid sodium symporter
AN415_RS16605	COG0640	Transcriptional regulator
AN415_RS16640	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AN415_RS16665	COG2132	Multicopper oxidase
AN415_RS16680	COG2205	protein histidine kinase activity
AN415_RS16760	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AN415_RS16770	COG0583	DNA-binding transcription factor activity
AN415_RS16775	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AN415_RS16785	COG0084	hydrolase, TatD family'
AN415_RS16800	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AN415_RS16830	COG0440	acetolactate synthase activity
AN415_RS16835	COG0028	Belongs to the TPP enzyme family
AN415_RS16860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AN415_RS16865	COG1136	(ABC) transporter
AN415_RS16865	COG0577	efflux transmembrane transporter activity
AN415_RS16870	COG1538	Outer membrane efflux protein
AN415_RS16885	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AN415_RS16890	COG1162	GTPase activity
AN415_RS16900	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AN415_RS16940	COG1426	Protein conserved in bacteria
AN415_RS16975	COG0793	Belongs to the peptidase S41A family
AN415_RS16990	COG2267	carboxylic ester hydrolase activity
AN415_RS17000	COG1012	belongs to the aldehyde dehydrogenase family
AN415_RS17005	COG3265	gluconokinase activity
AN415_RS17015	COG0800	Aldolase
AN415_RS17025	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AN415_RS17030	COG0857	belongs to the CobB CobQ family
AN415_RS17030	COG0280	phosphate acetyltransferase
AN415_RS17035	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AN415_RS17035	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AN415_RS17065	COG0740	serine-type endopeptidase activity
AN415_RS17075	COG4774	siderophore transport
AN415_RS17085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AN415_RS17095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AN415_RS17095	COG2813	Specifically methylates the guanine in position
AN415_RS17205	COG0788	formyltetrahydrofolate deformylase activity
AN415_RS17230	COG4651	solute:proton antiporter activity
AN415_RS17230	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN415_RS17250	COG0724	RNA recognition motif
AN415_RS17255	COG0210	DNA helicase
AN415_RS17280	COG1733	regulation of RNA biosynthetic process
AN415_RS17290	COG2900	Belongs to the SlyX family
AN415_RS17295	COG0488	(ABC) transporter
AN415_RS17300	COG1280	lysine exporter protein (LysE YggA)
AN415_RS17305	COG1560	Kdo2-lipid A biosynthetic process
AN415_RS17315	COG1301	dicarboxylic acid transport
AN415_RS17370	COG0473	3-isopropylmalate dehydrogenase activity
AN415_RS17425	COG0583	DNA-binding transcription factor activity
AN415_RS17435	COG0625	glutathione transferase activity
AN415_RS17440	COG2378	regulation of single-species biofilm formation
AN415_RS17445	COG0546	phosphoglycolate phosphatase activity
AN415_RS17460	COG1530	ribonuclease E activity
AN415_RS17465	COG0318	PFAM AMP-dependent synthetase and ligase
AN415_RS17480	COG0583	DNA-binding transcription factor activity
AN415_RS17485	COG4221	oxidoreductase activity
AN415_RS17490	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AN415_RS17500	COG0534	Mate efflux family protein
AN415_RS17515	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AN415_RS17540	COG0493	'glutamate synthase
AN415_RS17540	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AN415_RS17550	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AN415_RS17555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AN415_RS17570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AN415_RS17580	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AN415_RS17580	COG0644	oxidoreductase
AN415_RS17590	COG0425	Belongs to the sulfur carrier protein TusA family
AN415_RS17595	COG4535	Mg2 and Co2 transporter CorC
AN415_RS17605	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AN415_RS17625	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AN415_RS17630	COG0475	glutathione-regulated potassium exporter activity
AN415_RS17630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AN415_RS17645	COG0484	heat shock protein binding
AN415_RS17650	COG0789	Transcriptional regulator
AN415_RS17655	COG0598	Magnesium transport protein CorA
AN415_RS17670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AN415_RS17675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AN415_RS17680	COG1074	ATP-dependent DNA helicase activity
AN415_RS17685	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AN415_RS17705	COG2226	methyltransferase
AN415_RS17720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AN415_RS17725	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AN415_RS17750	COG2111	Na H antiporter
AN415_RS17750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AN415_RS17755	COG1006	Multisubunit Na H antiporter MnhC subunit
AN415_RS17760	COG0651	ATP synthesis coupled electron transport
AN415_RS17765	COG1863	multisubunit Na H antiporter MnhE subunit
AN415_RS17770	COG2212	antiporter activity
AN415_RS17775	COG1320	monovalent cation:proton antiporter activity
AN415_RS17790	COG0195	Participates in both transcription termination and antitermination
AN415_RS17840	COG0237	dephospho-CoA kinase activity
AN415_RS17850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AN415_RS17865	COG0497	DNA recombination
AN415_RS17875	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AN415_RS17905	COG2169	Transcriptional regulator
AN415_RS17905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AN415_RS17910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AN415_RS17975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AN415_RS17990	COG0326	Molecular chaperone. Has ATPase activity
AN415_RS18005	COG2056	Na+-H+ antiporter family
AN415_RS18105	COG0546	phosphoglycolate phosphatase activity
AN415_RS18110	COG1716	ATPase activity
AN415_RS18155	COG0181	hydroxymethylbilane synthase activity
AN415_RS18165	COG3275	phosphorelay sensor kinase activity
AN415_RS18185	COG1538	Outer membrane efflux protein
AN415_RS18190	COG0697	spore germination
AN415_RS18215	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AN415_RS18220	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AN415_RS18225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AN415_RS18230	COG0772	Belongs to the SEDS family
AN415_RS18255	COG4974	Belongs to the 'phage' integrase family
AN415_RS18260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AN415_RS18270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AN415_RS18280	COG2197	response regulator
AN415_RS18295	COG0793	Belongs to the peptidase S41A family
AN415_RS18300	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AN415_RS18305	COG0795	lipopolysaccharide-transporting ATPase activity
AN415_RS18345	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN415_RS18345	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AN415_RS18355	COG0004	ammonium transporteR
AN415_RS18360	COG0347	Belongs to the P(II) protein family
AN415_RS18370	COG0606	chelatase, subunit chli
AN415_RS18400	COG1061	Type III restriction enzyme res subunit
AN415_RS18420	COG0659	secondary active sulfate transmembrane transporter activity
AN415_RS18425	COG0589	response to stress
AN415_RS18465	COG0606	chelatase, subunit chli
AN415_RS18470	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AN415_RS18480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AN415_RS18505	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AN415_RS18520	COG0318	PFAM AMP-dependent synthetase and ligase
AN415_RS18530	COG0477	Major facilitator Superfamily
AN415_RS18535	COG2860	membrane
AN415_RS18540	COG3012	SEC-C Motif Domain Protein
AN415_RS18545	COG1253	flavin adenine dinucleotide binding
AN415_RS18555	COG0477	Major facilitator Superfamily
AN415_RS18565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AN415_RS18600	COG0655	NAD(P)H dehydrogenase (quinone) activity
AN415_RS18610	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AN415_RS18645	COG1309	transcriptional regulator
AN415_RS18680	COG0758	DNA mediated transformation
AN415_RS18690	COG0697	spore germination
AN415_RS18695	COG1309	transcriptional regulator
AN415_RS18710	COG0386	Belongs to the glutathione peroxidase family
AN415_RS18775	COG1121	(ABC) transporter
AN415_RS18780	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AN415_RS18785	COG1280	lysine exporter protein (LysE YggA)
AN415_RS18790	COG2837	iron assimilation
AN415_RS18795	COG0281	malic enzyme
AN415_RS18840	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AN415_RS18840	COG0519	Catalyzes the synthesis of GMP from XMP
AN415_RS18845	COG4399	Belongs to the UPF0754 family
AN415_RS18850	COG2259	Doxx family
AN415_RS18855	COG0586	Pfam SNARE associated Golgi protein
AN415_RS18870	COG1192	Involved in chromosome partitioning
AN415_RS18880	COG0271	Belongs to the BolA IbaG family
AN415_RS18900	COG2267	carboxylic ester hydrolase activity
AN415_RS18920	COG3321	synthase
AN415_RS18920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AN415_RS18920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AN415_RS18920	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AN415_RS18925	COG1960	acyl-CoA dehydrogenase activity
AN415_RS18935	COG2197	response regulator
AN415_RS18945	COG3916	Acyl-homoserine-lactone synthase
AN415_RS18950	COG0477	Major facilitator Superfamily
AN415_RS18955	COG1024	Enoyl-CoA hydratase
AN415_RS18960	COG1024	Enoyl-CoA hydratase
AN415_RS18965	COG1960	acyl-CoA dehydrogenase activity
AN415_RS18970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AN415_RS18990	COG1113	amino acid transport
AN415_RS18995	COG1113	amino acid transport
AN415_RS19000	COG0251	oxidation-reduction process
AN415_RS19040	COG0564	pseudouridine synthase activity
AN415_RS19075	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AN415_RS19090	COG1802	Transcriptional regulator
AN415_RS19095	COG1448	Aminotransferase
AN415_RS19100	COG0277	FAD linked oxidase domain protein
AN415_RS19110	COG2186	Transcriptional regulator
AN415_RS19120	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AN415_RS19125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AN415_RS19140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AN415_RS19155	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AN415_RS19170	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AN415_RS19210	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS19220	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS19225	COG1083	cytidylyl-transferase
AN415_RS19230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AN415_RS19240	COG2089	acid synthase
AN415_RS19245	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AN415_RS19250	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AN415_RS19260	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AN415_RS19290	COG0728	peptidoglycan biosynthetic process
AN415_RS19295	COG3023	N-Acetylmuramoyl-L-alanine amidase
AN415_RS19345	COG0546	phosphoglycolate phosphatase activity
AN415_RS19350	COG1028	Short-chain dehydrogenase reductase Sdr
AN415_RS19370	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN415_RS19375	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AN415_RS19380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AN415_RS19385	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AN415_RS19390	COG1116	anion transmembrane transporter activity
AN415_RS19395	COG1309	transcriptional regulator
AN415_RS19400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AN415_RS19410	COG0196	riboflavin kinase activity
AN415_RS19415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AN415_RS19425	COG1047	Peptidyl-prolyl cis-trans