locus-tag	class	description
AbD4_RS00005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AbD4_RS00010	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AbD4_RS00015	COG0596	Alpha beta hydrolase
AbD4_RS00040	COG0488	(ABC) transporter
AbD4_RS00045	COG0586	Pfam SNARE associated Golgi protein
AbD4_RS00055	COG0187	DNA topoisomerase II activity
AbD4_RS00065	COG0592	DNA-directed DNA polymerase activity
AbD4_RS00095	COG0706	membrane insertase activity
AbD4_RS00105	COG4974	Belongs to the 'phage' integrase family
AbD4_RS00270	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AbD4_RS00280	COG0675	Transposase, IS605 OrfB family
AbD4_RS00290	COG4372	Transposase
AbD4_RS00305	COG0675	Transposase, IS605 OrfB family
AbD4_RS00360	COG1230	cation diffusion facilitator family transporter
AbD4_RS00365	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AbD4_RS00380	COG0402	S-adenosylhomocysteine deaminase activity
AbD4_RS00390	COG0754	glutathionylspermidine amidase activity
AbD4_RS00400	COG0861	Integral membrane protein TerC family
AbD4_RS00405	COG0671	phosphoesterase, PA-phosphatase related
AbD4_RS00415	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AbD4_RS00430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AbD4_RS00435	COG2951	lytic endotransglycosylase activity
AbD4_RS00465	COG0583	DNA-binding transcription factor activity
AbD4_RS00485	COG0657	acetylesterase activity
AbD4_RS00490	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AbD4_RS00540	COG1047	Peptidyl-prolyl cis-trans
AbD4_RS00550	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AbD4_RS00555	COG0196	riboflavin kinase activity
AbD4_RS00565	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
AbD4_RS00570	COG1309	transcriptional regulator
AbD4_RS00575	COG1116	anion transmembrane transporter activity
AbD4_RS00580	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AbD4_RS00585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AbD4_RS00590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AbD4_RS00595	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AbD4_RS00615	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS00620	COG0546	phosphoglycolate phosphatase activity
AbD4_RS00675	COG3023	N-Acetylmuramoyl-L-alanine amidase
AbD4_RS00680	COG0728	peptidoglycan biosynthetic process
AbD4_RS00710	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AbD4_RS00715	COG1086	Polysaccharide biosynthesis protein
AbD4_RS00720	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AbD4_RS00725	COG1083	cytidylyl-transferase
AbD4_RS00740	COG2089	acid synthase
AbD4_RS00745	COG2244	polysaccharide biosynthetic process
AbD4_RS00760	COG1216	Glycosyl transferase, family 2
AbD4_RS00765	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AbD4_RS00770	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AbD4_RS00785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AbD4_RS00790	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AbD4_RS00800	COG2186	Transcriptional regulator
AbD4_RS00810	COG0277	FAD linked oxidase domain protein
AbD4_RS00815	COG1448	Aminotransferase
AbD4_RS00825	COG1802	Transcriptional regulator
AbD4_RS00840	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AbD4_RS00855	COG2963	transposase activity
AbD4_RS00865	COG4372	Transposase
AbD4_RS00955	COG0564	pseudouridine synthase activity
AbD4_RS00995	COG0251	oxidation-reduction process
AbD4_RS01000	COG1113	amino acid transport
AbD4_RS01005	COG1113	amino acid transport
AbD4_RS01025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AbD4_RS01030	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS01035	COG1024	Enoyl-CoA hydratase
AbD4_RS01040	COG1024	Enoyl-CoA hydratase
AbD4_RS01045	COG0477	Major facilitator Superfamily
AbD4_RS01050	COG3916	Acyl-homoserine-lactone synthase
AbD4_RS01060	COG2197	response regulator
AbD4_RS01070	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS01075	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
AbD4_RS01075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AbD4_RS01075	COG3321	synthase
AbD4_RS01075	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AbD4_RS01115	COG0271	Belongs to the BolA IbaG family
AbD4_RS01125	COG1192	Involved in chromosome partitioning
AbD4_RS01140	COG4372	Transposase
AbD4_RS01150	COG2963	transposase activity
AbD4_RS01160	COG0586	Pfam SNARE associated Golgi protein
AbD4_RS01165	COG2259	Doxx family
AbD4_RS01170	COG4399	Belongs to the UPF0754 family
AbD4_RS01175	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AbD4_RS01175	COG0519	Catalyzes the synthesis of GMP from XMP
AbD4_RS01220	COG0281	malic enzyme
AbD4_RS01225	COG2837	iron assimilation
AbD4_RS01230	COG1280	lysine exporter protein (LysE YggA)
AbD4_RS01235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AbD4_RS01240	COG1121	(ABC) transporter
AbD4_RS01305	COG0386	Belongs to the glutathione peroxidase family
AbD4_RS01320	COG1309	transcriptional regulator
AbD4_RS01325	COG0697	spore germination
AbD4_RS01335	COG0758	DNA mediated transformation
AbD4_RS01405	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AbD4_RS01415	COG0655	NAD(P)H dehydrogenase (quinone) activity
AbD4_RS01455	COG4452	Inner membrane protein CreD
AbD4_RS01460	COG2205	protein histidine kinase activity
AbD4_RS01465	COG0745	RESPONSE REGULATOR receiver
AbD4_RS01470	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AbD4_RS01480	COG0477	Major facilitator Superfamily
AbD4_RS01490	COG1253	flavin adenine dinucleotide binding
AbD4_RS01495	COG3012	SEC-C Motif Domain Protein
AbD4_RS01500	COG2860	membrane
AbD4_RS01505	COG0477	Major facilitator Superfamily
AbD4_RS01515	COG0318	PFAM AMP-dependent synthetase and ligase
AbD4_RS01530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AbD4_RS01545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AbD4_RS01560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AbD4_RS01565	COG0765	amino acid transport
AbD4_RS01570	COG1126	abc transporter atp-binding protein
AbD4_RS01595	COG0589	response to stress
AbD4_RS01600	COG0659	secondary active sulfate transmembrane transporter activity
AbD4_RS01620	COG0347	Belongs to the P(II) protein family
AbD4_RS01625	COG0004	ammonium transporteR
AbD4_RS01635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AbD4_RS01635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AbD4_RS01675	COG0795	lipopolysaccharide-transporting ATPase activity
AbD4_RS01680	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AbD4_RS01685	COG0793	Belongs to the peptidase S41A family
AbD4_RS01700	COG2197	response regulator
AbD4_RS01710	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AbD4_RS01720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AbD4_RS01725	COG4974	Belongs to the 'phage' integrase family
AbD4_RS01750	COG0772	Belongs to the SEDS family
AbD4_RS01755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AbD4_RS01760	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AbD4_RS01765	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AbD4_RS01790	COG0697	spore germination
AbD4_RS01795	COG1538	Outer membrane efflux protein
AbD4_RS01815	COG3275	phosphorelay sensor kinase activity
AbD4_RS01825	COG0181	hydroxymethylbilane synthase activity
AbD4_RS01870	COG1716	ATPase activity
AbD4_RS01875	COG0546	phosphoglycolate phosphatase activity
AbD4_RS01975	COG2056	Na+-H+ antiporter family
AbD4_RS01990	COG0326	Molecular chaperone. Has ATPase activity
AbD4_RS02005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AbD4_RS02075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AbD4_RS02080	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AbD4_RS02080	COG2169	Transcriptional regulator
AbD4_RS02110	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AbD4_RS02120	COG0497	DNA recombination
AbD4_RS02135	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AbD4_RS02145	COG0237	dephospho-CoA kinase activity
AbD4_RS02195	COG0195	Participates in both transcription termination and antitermination
AbD4_RS02210	COG1320	monovalent cation:proton antiporter activity
AbD4_RS02215	COG2212	antiporter activity
AbD4_RS02220	COG1863	multisubunit Na H antiporter MnhE subunit
AbD4_RS02225	COG0651	ATP synthesis coupled electron transport
AbD4_RS02230	COG1006	Multisubunit Na H antiporter MnhC subunit
AbD4_RS02235	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AbD4_RS02235	COG2111	Na H antiporter
AbD4_RS02250	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AbD4_RS02265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AbD4_RS02280	COG2226	methyltransferase
AbD4_RS02300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AbD4_RS02305	COG1074	ATP-dependent DNA helicase activity
AbD4_RS02310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AbD4_RS02315	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AbD4_RS02330	COG0598	Magnesium transport protein CorA
AbD4_RS02335	COG0789	Transcriptional regulator
AbD4_RS02340	COG0484	heat shock protein binding
AbD4_RS02355	COG0475	glutathione-regulated potassium exporter activity
AbD4_RS02355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AbD4_RS02360	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AbD4_RS02380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AbD4_RS02390	COG4535	Mg2 and Co2 transporter CorC
AbD4_RS02395	COG0425	Belongs to the sulfur carrier protein TusA family
AbD4_RS02405	COG0644	oxidoreductase
AbD4_RS02405	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AbD4_RS02415	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AbD4_RS02430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AbD4_RS02435	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
AbD4_RS02445	COG0493	'glutamate synthase
AbD4_RS02445	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AbD4_RS02475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AbD4_RS02490	COG0534	Mate efflux family protein
AbD4_RS02500	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AbD4_RS02505	COG4221	oxidoreductase activity
AbD4_RS02510	COG0583	DNA-binding transcription factor activity
AbD4_RS02525	COG0318	PFAM AMP-dependent synthetase and ligase
AbD4_RS02530	COG1530	ribonuclease E activity
AbD4_RS02540	COG0546	phosphoglycolate phosphatase activity
AbD4_RS02545	COG2378	regulation of single-species biofilm formation
AbD4_RS02550	COG0625	glutathione transferase activity
AbD4_RS02560	COG0583	DNA-binding transcription factor activity
AbD4_RS02615	COG0473	3-isopropylmalate dehydrogenase activity
AbD4_RS02670	COG1301	dicarboxylic acid transport
AbD4_RS02680	COG1560	Kdo2-lipid A biosynthetic process
AbD4_RS02685	COG1280	lysine exporter protein (LysE YggA)
AbD4_RS02695	COG0488	(ABC) transporter
AbD4_RS02700	COG2900	Belongs to the SlyX family
AbD4_RS02710	COG1733	regulation of RNA biosynthetic process
AbD4_RS02735	COG0210	DNA helicase
AbD4_RS02740	COG0724	RNA recognition motif
AbD4_RS02760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AbD4_RS02760	COG4651	solute:proton antiporter activity
AbD4_RS02785	COG0788	formyltetrahydrofolate deformylase activity
AbD4_RS02890	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AbD4_RS02890	COG2813	Specifically methylates the guanine in position
AbD4_RS02900	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AbD4_RS02910	COG4774	siderophore transport
AbD4_RS02920	COG0740	serine-type endopeptidase activity
AbD4_RS02940	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AbD4_RS02940	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AbD4_RS02945	COG0857	belongs to the CobB CobQ family
AbD4_RS02945	COG0280	phosphate acetyltransferase
AbD4_RS02950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AbD4_RS02960	COG0800	Aldolase
AbD4_RS02970	COG3265	gluconokinase activity
AbD4_RS02975	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS02985	COG2267	carboxylic ester hydrolase activity
AbD4_RS03000	COG0793	Belongs to the peptidase S41A family
AbD4_RS03035	COG1426	Protein conserved in bacteria
AbD4_RS03075	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
AbD4_RS03085	COG1162	GTPase activity
AbD4_RS03090	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AbD4_RS03105	COG1538	Outer membrane efflux protein
AbD4_RS03110	COG0577	efflux transmembrane transporter activity
AbD4_RS03110	COG1136	(ABC) transporter
AbD4_RS03120	COG4372	Transposase
AbD4_RS03130	COG2963	transposase activity
AbD4_RS03160	COG0028	Belongs to the TPP enzyme family
AbD4_RS03165	COG0440	acetolactate synthase activity
AbD4_RS03220	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AbD4_RS03235	COG0084	hydrolase, TatD family'
AbD4_RS03250	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AbD4_RS03260	COG0583	DNA-binding transcription factor activity
AbD4_RS03270	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AbD4_RS03305	COG4372	Transposase
AbD4_RS03315	COG2963	transposase activity
AbD4_RS03380	COG2963	transposase activity
AbD4_RS03390	COG4372	Transposase
AbD4_RS03410	COG2132	Multicopper oxidase
AbD4_RS03420	COG0789	Transcriptional regulator
AbD4_RS03455	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AbD4_RS03470	COG0640	Transcriptional regulator
AbD4_RS03480	COG0798	PFAM Bile acid sodium symporter
AbD4_RS03485	COG2963	transposase activity
AbD4_RS03495	COG4372	Transposase
AbD4_RS03515	COG2814	Major facilitator Superfamily
AbD4_RS03525	COG0697	spore germination
AbD4_RS03555	COG3622	Belongs to the hyi family
AbD4_RS03560	COG2084	Dehydrogenase
AbD4_RS03565	COG1024	Enoyl-CoA hydratase
AbD4_RS03570	COG0784	Response regulator, receiver
AbD4_RS03570	COG2205	protein histidine kinase activity
AbD4_RS03570	COG5002	protein histidine kinase activity
AbD4_RS03590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AbD4_RS03600	COG3956	TIGRFAM MazG family protein
AbD4_RS03605	COG1555	photosystem II stabilization
AbD4_RS03610	COG0617	tRNA 3'-terminal CCA addition
AbD4_RS03615	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AbD4_RS03635	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AbD4_RS03640	COG3028	Belongs to the UPF0307 family
AbD4_RS03645	COG0318	PFAM AMP-dependent synthetase and ligase
AbD4_RS03660	COG0625	glutathione transferase activity
AbD4_RS03665	COG1238	metal cluster binding
AbD4_RS03705	COG0072	phenylalanine-tRNA ligase activity
AbD4_RS03735	COG0248	Ppx GppA phosphatase
AbD4_RS03745	COG0037	tRNA processing
AbD4_RS03785	COG1764	response to oxidative stress
AbD4_RS03790	COG1846	Transcriptional regulator
AbD4_RS03800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AbD4_RS03860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AbD4_RS03865	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AbD4_RS03870	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AbD4_RS03880	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AbD4_RS03930	COG1214	PFAM Peptidase M22, glycoprotease
AbD4_RS03945	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
AbD4_RS03955	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AbD4_RS03960	COG0561	phosphatase activity
AbD4_RS03970	COG2132	Multicopper oxidase
AbD4_RS03990	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AbD4_RS03995	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AbD4_RS04000	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AbD4_RS04030	COG1063	alcohol dehydrogenase
AbD4_RS04035	COG0583	DNA-binding transcription factor activity
AbD4_RS04040	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS04045	COG2814	Major facilitator Superfamily
AbD4_RS04050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AbD4_RS04060	COG1053	succinate dehydrogenase
AbD4_RS04065	COG0583	DNA-binding transcription factor activity
AbD4_RS04080	COG0583	DNA-binding transcription factor activity
AbD4_RS04110	COG0583	DNA-binding transcription factor activity
AbD4_RS04125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AbD4_RS04130	COG1309	transcriptional regulator
AbD4_RS04150	COG0384	phenazine biosynthesis protein PhzF
AbD4_RS04155	COG4372	Transposase
AbD4_RS04165	COG2963	transposase activity
AbD4_RS04180	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AbD4_RS04200	COG0745	RESPONSE REGULATOR receiver
AbD4_RS04240	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
AbD4_RS04270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AbD4_RS04275	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AbD4_RS04295	COG0583	DNA-binding transcription factor activity
AbD4_RS04315	COG0668	transmembrane transport
AbD4_RS04325	COG2081	HI0933 family
AbD4_RS04330	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AbD4_RS04360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AbD4_RS04360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AbD4_RS04370	COG0489	protein tyrosine kinase activity
AbD4_RS04425	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AbD4_RS04435	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AbD4_RS04450	COG0730	response to heat
AbD4_RS04460	COG1196	nuclear chromosome segregation
AbD4_RS04480	COG2223	nitrite transmembrane transporter activity
AbD4_RS04485	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AbD4_RS04490	COG1877	trehalose-phosphatase activity
AbD4_RS04495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AbD4_RS04495	COG0596	Alpha beta hydrolase
AbD4_RS04495	COG2226	methyltransferase
AbD4_RS04510	COG4106	trans-aconitate 2-methyltransferase activity
AbD4_RS04525	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AbD4_RS04530	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AbD4_RS04535	COG0009	L-threonylcarbamoyladenylate synthase
AbD4_RS04540	COG3101	peptidyl-lysine hydroxylation
AbD4_RS04545	COG1399	metal-binding, possibly nucleic acid-binding protein
AbD4_RS04570	COG1652	LysM domain
AbD4_RS04575	COG0351	phosphomethylpyrimidine kinase
AbD4_RS04575	COG0352	thiamine-phosphate diphosphorylase activity
AbD4_RS04575	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AbD4_RS04585	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AbD4_RS04615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AbD4_RS04645	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
AbD4_RS04660	COG0358	DNA primase activity
AbD4_RS04670	COG0564	pseudouridine synthase activity
AbD4_RS04695	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AbD4_RS04715	COG0583	DNA-binding transcription factor activity
AbD4_RS04720	COG0473	3-isopropylmalate dehydrogenase activity
AbD4_RS04730	COG0657	acetylesterase activity
AbD4_RS04740	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS04760	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AbD4_RS04760	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AbD4_RS04775	COG1981	membrane
AbD4_RS04820	COG0456	acetyltransferase
AbD4_RS04830	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AbD4_RS04835	COG0492	ferredoxin-NADP+ reductase activity
AbD4_RS04840	COG1674	ftsk spoiiie
AbD4_RS04840	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AbD4_RS04845	COG1280	lysine exporter protein (LysE YggA)
AbD4_RS04855	COG2963	transposase activity
AbD4_RS04865	COG4372	Transposase
AbD4_RS04880	COG2894	cell division
AbD4_RS04895	COG0204	Acyl-transferase
AbD4_RS04900	COG2885	chlorophyll binding
AbD4_RS04905	COG0210	DNA helicase
AbD4_RS04915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AbD4_RS04930	COG0121	glutamine amidotransferase
AbD4_RS04950	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AbD4_RS04955	COG0735	belongs to the Fur family
AbD4_RS04980	COG0420	3'-5' exonuclease activity
AbD4_RS05000	COG1090	epimerase
AbD4_RS05015	COG2050	protein possibly involved in aromatic compounds catabolism
AbD4_RS05025	COG2814	Major facilitator Superfamily
AbD4_RS05030	COG0405	Gamma-glutamyltransferase
AbD4_RS05095	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
AbD4_RS05105	COG0477	Major facilitator Superfamily
AbD4_RS05110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AbD4_RS05120	COG1595	DNA-templated transcription, initiation
AbD4_RS05175	COG0531	amino acid
AbD4_RS05180	COG2040	homocysteine
AbD4_RS05205	COG1309	transcriptional regulator
AbD4_RS05210	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AbD4_RS05215	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AbD4_RS05225	COG1607	acyl-coa hydrolase
AbD4_RS05235	COG0523	cobalamin synthesis protein
AbD4_RS05245	COG4681	YaeQ
AbD4_RS05255	COG0726	polysaccharide deacetylase
AbD4_RS05255	COG1649	PFAM Uncharacterised BCR, COG1649
AbD4_RS05260	COG1215	transferase activity, transferring glycosyl groups
AbD4_RS05270	COG1024	Enoyl-CoA hydratase
AbD4_RS05285	COG1414	Transcriptional regulator
AbD4_RS05305	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS05320	COG2271	Major facilitator Superfamily
AbD4_RS05330	COG2267	carboxylic ester hydrolase activity
AbD4_RS05335	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS05350	COG0028	Belongs to the TPP enzyme family
AbD4_RS05360	COG0477	Major facilitator Superfamily
AbD4_RS05365	COG0242	peptide deformylase activity
AbD4_RS05370	COG2066	Belongs to the glutaminase family
AbD4_RS05375	COG2207	Transcriptional regulator
AbD4_RS05380	COG2223	nitrite transmembrane transporter activity
AbD4_RS05395	COG0583	DNA-binding transcription factor activity
AbD4_RS05400	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS05405	COG2271	Major facilitator Superfamily
AbD4_RS05410	COG3959	Transketolase, thiamine diphosphate binding domain
AbD4_RS05415	COG3958	Transketolase
AbD4_RS05425	COG0306	phosphate transporter
AbD4_RS05445	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AbD4_RS05490	COG4181	ATPase activity
AbD4_RS05495	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AbD4_RS05525	COG0583	DNA-binding transcription factor activity
AbD4_RS05535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AbD4_RS05540	COG1773	rubredoxin
AbD4_RS05590	COG2851	Citrate transporter
AbD4_RS05595	COG1253	flavin adenine dinucleotide binding
AbD4_RS05635	COG0804	urea catabolic process
AbD4_RS05645	COG0830	nickel cation binding
AbD4_RS05660	COG0742	ribosomal rna small subunit methyltransferase
AbD4_RS05665	COG0768	penicillin binding
AbD4_RS05690	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AbD4_RS05695	COG2878	Part of a membrane complex involved in electron transport
AbD4_RS05700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AbD4_RS05710	COG3384	dioxygenase
AbD4_RS05725	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AbD4_RS05765	COG0006	proline dipeptidase activity
AbD4_RS05770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AbD4_RS05775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AbD4_RS05795	COG1279	arginine transmembrane transporter activity
AbD4_RS05800	COG0583	DNA-binding transcription factor activity
AbD4_RS05840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AbD4_RS05845	COG0741	lytic transglycosylase activity
AbD4_RS05845	COG1388	LysM domain
AbD4_RS05845	COG0741	lytic transglycosylase activity
AbD4_RS05845	COG1388	LysM domain
AbD4_RS05855	COG4174	ABC transporter (Permease)
AbD4_RS05860	COG4239	(ABC) transporter, permease
AbD4_RS05865	COG4172	Belongs to the ABC transporter superfamily
AbD4_RS05885	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AbD4_RS05895	COG2203	Gaf domain
AbD4_RS05895	COG3706	GGDEF domain
AbD4_RS05895	COG4251	negative regulation of phosphorylation
AbD4_RS05895	COG5001	Diguanylate cyclase
AbD4_RS05900	COG2963	transposase activity
AbD4_RS05910	COG4372	Transposase
AbD4_RS05925	COG0446	pyridine nucleotide-disulphide oxidoreductase
AbD4_RS05925	COG1902	pentaerythritol trinitrate reductase activity
AbD4_RS05940	COG4372	Transposase
AbD4_RS05950	COG2963	transposase activity
AbD4_RS05965	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AbD4_RS05975	COG0583	DNA-binding transcription factor activity
AbD4_RS05980	COG2814	Major facilitator Superfamily
AbD4_RS05995	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS06000	COG1454	alcohol dehydrogenase
AbD4_RS06005	COG3485	protocatechuate 3,4-dioxygenase
AbD4_RS06020	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AbD4_RS06025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AbD4_RS06030	COG0183	Belongs to the thiolase family
AbD4_RS06065	COG1113	amino acid transport
AbD4_RS06075	COG0531	amino acid
AbD4_RS06095	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS06115	COG1113	amino acid transport
AbD4_RS06130	COG0697	spore germination
AbD4_RS06135	COG2721	sulfolactate sulfo-lyase activity
AbD4_RS06140	COG2271	Major facilitator Superfamily
AbD4_RS06145	COG4948	Mandelate Racemase Muconate Lactonizing
AbD4_RS06155	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS06160	COG2186	Transcriptional regulator
AbD4_RS06185	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS06195	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS06200	COG1024	Enoyl-CoA hydratase
AbD4_RS06205	COG2814	Major facilitator Superfamily
AbD4_RS06220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AbD4_RS06235	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AbD4_RS06280	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AbD4_RS06295	COG0583	DNA-binding transcription factor activity
AbD4_RS06300	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AbD4_RS06305	COG2072	flavoprotein involved in K transport
AbD4_RS06310	COG0300	oxidoreductase activity
AbD4_RS06320	COG1309	transcriptional regulator
AbD4_RS06325	COG1741	Belongs to the pirin family
AbD4_RS06340	COG2072	flavoprotein involved in K transport
AbD4_RS06350	COG2252	PERMEase
AbD4_RS06355	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AbD4_RS06360	COG3038	cytochrome b561
AbD4_RS06370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AbD4_RS06380	COG0527	aspartate kinase activity
AbD4_RS06390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AbD4_RS06400	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AbD4_RS06415	COG0667	Aldo Keto reductase
AbD4_RS06430	COG1765	OsmC-like protein
AbD4_RS06445	COG0542	response to heat
AbD4_RS06480	COG2885	chlorophyll binding
AbD4_RS06490	COG0625	glutathione transferase activity
AbD4_RS06495	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AbD4_RS06515	COG3634	alkyl hydroperoxide reductase activity
AbD4_RS06525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AbD4_RS06535	COG0450	alkyl hydroperoxide reductase
AbD4_RS06540	COG1643	Atp-dependent helicase
AbD4_RS06555	COG2814	Major facilitator Superfamily
AbD4_RS06560	COG3135	benzoate transporter
AbD4_RS06565	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS06570	COG0543	2 iron, 2 sulfur cluster binding
AbD4_RS06570	COG0633	Ferredoxin
AbD4_RS06580	COG4638	Rieske (2fe-2S)
AbD4_RS06590	COG0583	DNA-binding transcription factor activity
AbD4_RS06600	COG2871	sodium ion transport
AbD4_RS06680	COG1570	exodeoxyribonuclease VII activity
AbD4_RS06710	COG1280	lysine exporter protein (LysE YggA)
AbD4_RS06715	COG1278	Cold shock
AbD4_RS06750	COG2814	Major facilitator Superfamily
AbD4_RS06885	COG3728	DNA packaging
AbD4_RS06885	COG5484	DNA packaging
AbD4_RS07030	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AbD4_RS07040	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AbD4_RS07045	COG1137	ATPase activity
AbD4_RS07090	COG4122	O-methyltransferase activity
AbD4_RS07100	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AbD4_RS07115	COG1522	sequence-specific DNA binding
AbD4_RS07120	COG5006	permease, DMT superfamily
AbD4_RS07130	COG1560	Kdo2-lipid A biosynthetic process
AbD4_RS07135	COG0598	Magnesium transport protein CorA
AbD4_RS07150	COG2814	Major facilitator Superfamily
AbD4_RS07170	COG1250	3-hydroxyacyl-CoA dehydrogenase
AbD4_RS07190	COG0583	DNA-binding transcription factor activity
AbD4_RS07195	COG1914	H( )-stimulated, divalent metal cation uptake system
AbD4_RS07215	COG4770	biotin carboxylase activity
AbD4_RS07220	COG0038	chloride channel
AbD4_RS07225	COG2831	hemolysin activation secretion protein
AbD4_RS07230	COG3210	domain, Protein
AbD4_RS07240	COG1309	transcriptional regulator
AbD4_RS07250	COG1063	alcohol dehydrogenase
AbD4_RS07265	COG0439	Biotin carboxylase
AbD4_RS07270	COG2249	NAD(P)H dehydrogenase (quinone) activity
AbD4_RS07275	COG1733	regulation of RNA biosynthetic process
AbD4_RS07285	COG0864	Transcriptional regulator
AbD4_RS07295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AbD4_RS07300	COG1116	anion transmembrane transporter activity
AbD4_RS07330	COG4372	Transposase
AbD4_RS07340	COG2963	transposase activity
AbD4_RS07480	COG0590	tRNA wobble adenosine to inosine editing
AbD4_RS07485	COG2807	transmembrane transport
AbD4_RS07500	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AbD4_RS07510	COG0789	Transcriptional regulator
AbD4_RS07520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AbD4_RS07540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AbD4_RS07565	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS07570	COG0531	amino acid
AbD4_RS07575	COG1760	l-serine dehydratase
AbD4_RS07580	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS07580	COG2030	dehydratase
AbD4_RS07585	COG3396	Phenylacetate-CoA oxygenase
AbD4_RS07590	COG3460	Phenylacetate-CoA oxygenase
AbD4_RS07595	COG3396	Phenylacetate-CoA oxygenase
AbD4_RS07600	COG2151	metal-sulfur cluster biosynthetic enzyme
AbD4_RS07605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AbD4_RS07610	COG1024	Enoyl-CoA hydratase
AbD4_RS07615	COG1024	Enoyl-CoA hydratase
AbD4_RS07620	COG1250	3-hydroxyacyl-CoA dehydrogenase
AbD4_RS07625	COG0183	Belongs to the thiolase family
AbD4_RS07630	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AbD4_RS07635	COG3327	negative regulation of DNA-templated transcription, initiation
AbD4_RS07645	COG2050	protein possibly involved in aromatic compounds catabolism
AbD4_RS07655	COG0556	nucleotide-excision repair
AbD4_RS07670	COG2207	Transcriptional regulator
AbD4_RS07685	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AbD4_RS07690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AbD4_RS07695	COG2271	Major facilitator Superfamily
AbD4_RS07700	COG0753	catalase activity
AbD4_RS07705	COG3038	cytochrome b561
AbD4_RS07725	COG2267	carboxylic ester hydrolase activity
AbD4_RS07730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AbD4_RS07735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AbD4_RS07740	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS07750	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AbD4_RS07760	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS07765	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AbD4_RS07770	COG0583	DNA-binding transcription factor activity
AbD4_RS07780	COG1414	Transcriptional regulator
AbD4_RS07785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AbD4_RS07795	COG1840	ABC-type Fe3 transport system, periplasmic component
AbD4_RS07800	COG3842	ATPase activity
AbD4_RS07815	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AbD4_RS07820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AbD4_RS07825	COG2814	Major facilitator Superfamily
AbD4_RS07830	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS07845	COG1024	Enoyl-CoA hydratase
AbD4_RS07855	COG2814	Major facilitator Superfamily
AbD4_RS07865	COG0183	Belongs to the thiolase family
AbD4_RS07870	COG1250	3-hydroxyacyl-CoA dehydrogenase
AbD4_RS07875	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS07880	COG1024	Enoyl-CoA hydratase
AbD4_RS07885	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS07890	COG2814	Major facilitator Superfamily
AbD4_RS07895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AbD4_RS07900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AbD4_RS07910	COG2814	Major facilitator Superfamily
AbD4_RS07920	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS07935	COG0583	DNA-binding transcription factor activity
AbD4_RS07945	COG4770	biotin carboxylase activity
AbD4_RS07950	COG1024	Enoyl-CoA hydratase
AbD4_RS07955	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AbD4_RS07960	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS07965	COG1309	transcriptional regulator
AbD4_RS07970	COG0318	PFAM AMP-dependent synthetase and ligase
AbD4_RS07990	COG0583	DNA-binding transcription factor activity
AbD4_RS08040	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS08060	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AbD4_RS08080	COG2205	protein histidine kinase activity
AbD4_RS08080	COG0784	Response regulator, receiver
AbD4_RS08120	COG0765	amino acid transport
AbD4_RS08125	COG0765	amino acid transport
AbD4_RS08135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AbD4_RS08140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AbD4_RS08155	COG1280	lysine exporter protein (LysE YggA)
AbD4_RS08160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AbD4_RS08165	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AbD4_RS08170	COG1045	serine acetyltransferase
AbD4_RS08185	COG0583	DNA-binding transcription factor activity
AbD4_RS08190	COG0625	glutathione transferase activity
AbD4_RS08195	COG0625	glutathione transferase activity
AbD4_RS08200	COG0583	DNA-binding transcription factor activity
AbD4_RS08210	COG1346	cytolysis
AbD4_RS08235	COG0300	oxidoreductase activity
AbD4_RS08245	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
AbD4_RS08250	COG3052	prosthetic group binding
AbD4_RS08270	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AbD4_RS08290	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AbD4_RS08300	COG1294	oxidase, subunit
AbD4_RS08305	COG1271	oxidase subunit
AbD4_RS08325	COG0477	Major facilitator Superfamily
AbD4_RS08335	COG4521	taurine ABC transporter
AbD4_RS08340	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
AbD4_RS08345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AbD4_RS08350	COG2175	clavaminate synthase activity
AbD4_RS08360	COG1953	Uracil, thiamine, allantoin
AbD4_RS08370	COG0583	DNA-binding transcription factor activity
AbD4_RS08380	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
AbD4_RS08395	COG0640	Transcriptional regulator
AbD4_RS08400	COG0798	PFAM Bile acid sodium symporter
AbD4_RS08405	COG0583	DNA-binding transcription factor activity
AbD4_RS08420	COG3634	alkyl hydroperoxide reductase activity
AbD4_RS08460	COG0436	Aminotransferase
AbD4_RS08470	COG0386	Belongs to the glutathione peroxidase family
AbD4_RS08485	COG4372	Transposase
AbD4_RS08495	COG2963	transposase activity
AbD4_RS08525	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AbD4_RS08550	COG0012	GTP binding
AbD4_RS08555	COG2011	ABC-type metal ion transport system permease component
AbD4_RS08560	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AbD4_RS08570	COG1464	Belongs to the NlpA lipoprotein family
AbD4_RS08600	COG0765	amino acid transport
AbD4_RS08605	COG0765	amino acid transport
AbD4_RS08610	COG1126	abc transporter atp-binding protein
AbD4_RS08620	COG1522	sequence-specific DNA binding
AbD4_RS08635	COG1309	transcriptional regulator
AbD4_RS08655	COG0583	DNA-binding transcription factor activity
AbD4_RS08665	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
AbD4_RS08675	COG0697	spore germination
AbD4_RS08700	COG3121	Chaperone
AbD4_RS08705	COG3539	Fimbrial protein
AbD4_RS08730	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AbD4_RS08730	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AbD4_RS08775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AbD4_RS08785	COG2353	YceI-like domain
AbD4_RS08795	COG3698	Phosphodiester glycosidase
AbD4_RS08810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
AbD4_RS08815	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AbD4_RS08815	COG0506	proline dehydrogenase activity
AbD4_RS08815	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
AbD4_RS08825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AbD4_RS08830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AbD4_RS08850	COG1132	(ABC) transporter
AbD4_RS08855	COG3122	Protein conserved in bacteria
AbD4_RS08860	COG3619	membrane
AbD4_RS08870	COG0640	Transcriptional regulator
AbD4_RS08880	COG2850	peptidyl-arginine hydroxylation
AbD4_RS08885	COG0424	maF-like protein
AbD4_RS08905	COG0191	fructose-bisphosphate aldolase activity
AbD4_RS08910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AbD4_RS08925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AbD4_RS08935	COG1192	Involved in chromosome partitioning
AbD4_RS08940	COG1475	DNA binding
AbD4_RS08945	COG0811	peptide transport
AbD4_RS08955	COG1132	(ABC) transporter
AbD4_RS08960	COG1663	tetraacyldisaccharide 4'-kinase activity
AbD4_RS08980	COG0084	hydrolase, TatD family'
AbD4_RS09045	COG0776	regulation of translation
AbD4_RS09075	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AbD4_RS09080	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AbD4_RS09115	COG4372	Transposase
AbD4_RS09125	COG2963	transposase activity
AbD4_RS09140	COG4166	transmembrane transport
AbD4_RS09160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AbD4_RS09195	COG0702	epimerase
AbD4_RS09200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AbD4_RS09220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AbD4_RS09250	COG0316	Belongs to the HesB IscA family
AbD4_RS09255	COG0822	iron-sulfur transferase activity
AbD4_RS09280	COG0776	regulation of translation
AbD4_RS09285	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AbD4_RS09290	COG2207	Transcriptional regulator
AbD4_RS09295	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AbD4_RS09300	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS09305	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS09320	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AbD4_RS09340	COG4264	IucA IucC family
AbD4_RS09345	COG4264	IucA IucC family
AbD4_RS09355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AbD4_RS09385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AbD4_RS09400	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AbD4_RS09405	COG0406	alpha-ribazole phosphatase activity
AbD4_RS09420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AbD4_RS09425	COG0730	response to heat
AbD4_RS09445	COG4773	Receptor
AbD4_RS09450	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AbD4_RS09465	COG1131	(ABC) transporter
AbD4_RS09470	COG0842	Transport permease protein
AbD4_RS09475	COG0842	Transport permease protein
AbD4_RS09530	COG2226	methyltransferase
AbD4_RS09555	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AbD4_RS09590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AbD4_RS09600	COG0133	tryptophan synthase activity
AbD4_RS09615	COG3706	GGDEF domain
AbD4_RS09630	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AbD4_RS09635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AbD4_RS09640	COG0022	dehydrogenase e1 component
AbD4_RS09645	COG0508	dehydrogenase complex catalyzes the overall conversion of
AbD4_RS09650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AbD4_RS09660	COG1063	alcohol dehydrogenase
AbD4_RS09665	COG3781	membrane
AbD4_RS09675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AbD4_RS09675	COG3453	Protein conserved in bacteria
AbD4_RS09685	COG0730	response to heat
AbD4_RS09700	COG2207	Transcriptional regulator
AbD4_RS09700	COG3708	Transcriptional regulator
AbD4_RS09705	COG1733	regulation of RNA biosynthetic process
AbD4_RS09710	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AbD4_RS09720	COG2188	Transcriptional regulator
AbD4_RS09735	COG4521	taurine ABC transporter
AbD4_RS09740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AbD4_RS09760	COG0477	Major facilitator Superfamily
AbD4_RS09770	COG1027	Aspartate ammonia-lyase
AbD4_RS09785	COG0583	DNA-binding transcription factor activity
AbD4_RS09790	COG0583	DNA-binding transcription factor activity
AbD4_RS09795	COG0183	Belongs to the thiolase family
AbD4_RS09800	COG2031	fatty acid transporter
AbD4_RS09815	COG0583	DNA-binding transcription factor activity
AbD4_RS09835	COG1309	transcriptional regulator
AbD4_RS09845	COG2610	gluconate transmembrane transporter activity
AbD4_RS09850	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS09855	COG2207	Transcriptional regulator
AbD4_RS09870	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS09880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AbD4_RS09895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AbD4_RS09895	COG0543	2 iron, 2 sulfur cluster binding
AbD4_RS09900	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AbD4_RS09905	COG4638	Rieske (2fe-2S)
AbD4_RS09915	COG0725	ABC transporter, periplasmic molybdate-binding protein
AbD4_RS09920	COG4149	molybdate abc transporter
AbD4_RS09925	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AbD4_RS09930	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS09935	COG1535	isochorismatase
AbD4_RS09935	COG3433	isochorismatase activity
AbD4_RS09995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AbD4_RS10010	COG0753	catalase activity
AbD4_RS10020	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
AbD4_RS10050	COG3539	Fimbrial protein
AbD4_RS10075	COG0747	negative chemotaxis
AbD4_RS10080	COG0601	transmembrane transport
AbD4_RS10085	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AbD4_RS10105	COG1132	(ABC) transporter
AbD4_RS10110	COG1132	(ABC) transporter
AbD4_RS10130	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AbD4_RS10145	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AbD4_RS10165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AbD4_RS10170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AbD4_RS10175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AbD4_RS10205	COG4771	TonB-dependent receptor
AbD4_RS10210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AbD4_RS10220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AbD4_RS10225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AbD4_RS10230	COG0745	RESPONSE REGULATOR receiver
AbD4_RS10235	COG2205	protein histidine kinase activity
AbD4_RS10245	COG2207	Transcriptional regulator
AbD4_RS10260	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS10275	COG4372	Transposase
AbD4_RS10285	COG2963	transposase activity
AbD4_RS10315	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AbD4_RS10365	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AbD4_RS10385	COG1120	ATPase activity
AbD4_RS10400	COG1064	alcohol dehydrogenase
AbD4_RS10415	COG2207	Transcriptional regulator
AbD4_RS10420	COG2084	Dehydrogenase
AbD4_RS10430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AbD4_RS10435	COG0583	DNA-binding transcription factor activity
AbD4_RS10445	COG0129	dihydroxy-acid dehydratase activity
AbD4_RS10450	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS10465	COG1566	PFAM secretion protein HlyD family protein
AbD4_RS10475	COG2271	Major facilitator Superfamily
AbD4_RS10490	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AbD4_RS10515	COG0583	DNA-binding transcription factor activity
AbD4_RS10530	COG2188	Transcriptional regulator
AbD4_RS10570	COG4993	Dehydrogenase
AbD4_RS10575	COG1733	regulation of RNA biosynthetic process
AbD4_RS10590	COG2259	Doxx family
AbD4_RS10595	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AbD4_RS10610	COG4372	Transposase
AbD4_RS10620	COG2963	transposase activity
AbD4_RS10635	COG2963	transposase activity
AbD4_RS10645	COG4372	Transposase
AbD4_RS10675	COG1309	transcriptional regulator
AbD4_RS10705	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AbD4_RS10715	COG0446	pyridine nucleotide-disulphide oxidoreductase
AbD4_RS10715	COG1902	pentaerythritol trinitrate reductase activity
AbD4_RS10720	COG1846	Transcriptional regulator
AbD4_RS10740	COG0753	catalase activity
AbD4_RS10755	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS10770	COG3162	membrane
AbD4_RS10780	COG3829	transcription factor binding
AbD4_RS10785	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS10790	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS10805	COG3231	kanamycin kinase activity
AbD4_RS10810	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS10830	COG2186	Transcriptional regulator
AbD4_RS10840	COG0583	DNA-binding transcription factor activity
AbD4_RS10845	COG4948	Mandelate Racemase Muconate Lactonizing
AbD4_RS10850	COG4829	muconolactone delta-isomerase
AbD4_RS10860	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AbD4_RS10865	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AbD4_RS10870	COG0183	Belongs to the thiolase family
AbD4_RS10875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AbD4_RS10880	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS10890	COG3733	amine oxidase
AbD4_RS10900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AbD4_RS10910	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS10920	COG4638	Rieske (2fe-2S)
AbD4_RS10940	COG0154	amidase activity
AbD4_RS10950	COG2814	Major facilitator Superfamily
AbD4_RS10975	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS10980	COG0583	DNA-binding transcription factor activity
AbD4_RS10985	COG1414	Transcriptional regulator
AbD4_RS11000	COG2391	methyltransferase activity
AbD4_RS11010	COG4993	Dehydrogenase
AbD4_RS11015	COG3659	wide pore channel activity
AbD4_RS11020	COG3420	alginic acid biosynthetic process
AbD4_RS11025	COG0710	3-dehydroquinate dehydratase activity
AbD4_RS11030	COG3485	protocatechuate 3,4-dioxygenase
AbD4_RS11035	COG3485	protocatechuate 3,4-dioxygenase
AbD4_RS11040	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AbD4_RS11045	COG2271	Major facilitator Superfamily
AbD4_RS11050	COG0596	Alpha beta hydrolase
AbD4_RS11055	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AbD4_RS11060	COG0183	Belongs to the thiolase family
AbD4_RS11065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AbD4_RS11070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AbD4_RS11080	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AbD4_RS11085	COG2323	membrane
AbD4_RS11115	COG4372	Transposase
AbD4_RS11125	COG2963	transposase activity
AbD4_RS11160	COG1902	pentaerythritol trinitrate reductase activity
AbD4_RS11160	COG0446	pyridine nucleotide-disulphide oxidoreductase
AbD4_RS11185	COG0542	response to heat
AbD4_RS11190	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AbD4_RS11220	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AbD4_RS11225	COG0569	domain protein
AbD4_RS11230	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AbD4_RS11245	COG4774	siderophore transport
AbD4_RS11250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AbD4_RS11260	COG1585	Membrane protein implicated in regulation of membrane protease activity
AbD4_RS11275	COG1294	oxidase, subunit
AbD4_RS11280	COG4890	Cyd operon protein YbgT
AbD4_RS11290	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
AbD4_RS11300	COG0552	protein localization to endoplasmic reticulum
AbD4_RS11325	COG0517	IMP dehydrogenase activity
AbD4_RS11325	COG0516	GMP reductase activity
AbD4_RS11330	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AbD4_RS11335	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AbD4_RS11345	COG0583	DNA-binding transcription factor activity
AbD4_RS11350	COG0024	Methionine aminopeptidase
AbD4_RS11370	COG2963	transposase activity
AbD4_RS11380	COG4372	Transposase
AbD4_RS11395	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
AbD4_RS11395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AbD4_RS11400	COG1105	Belongs to the carbohydrate kinase PfkB family
AbD4_RS11405	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AbD4_RS11405	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
AbD4_RS11405	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
AbD4_RS11420	COG5001	Diguanylate cyclase
AbD4_RS11420	COG3300	MHYT domain
AbD4_RS11435	COG2135	peptidase activity
AbD4_RS11440	COG0659	secondary active sulfate transmembrane transporter activity
AbD4_RS11455	COG1113	amino acid transport
AbD4_RS11465	COG1522	sequence-specific DNA binding
AbD4_RS11490	COG1011	Hydrolase
AbD4_RS11495	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AbD4_RS11505	COG2137	regulation of response to DNA damage stimulus
AbD4_RS11520	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AbD4_RS11555	COG0575	Belongs to the CDS family
AbD4_RS11560	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AbD4_RS11585	COG3852	Histidine kinase
AbD4_RS11590	COG2204	response regulator
AbD4_RS11645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AbD4_RS11650	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AbD4_RS11670	COG0697	spore germination
AbD4_RS11675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AbD4_RS11685	COG0303	'Molybdopterin
AbD4_RS11690	COG0315	cyclic pyranopterin monophosphate synthase activity
AbD4_RS11690	COG0521	Mo-molybdopterin cofactor biosynthetic process
AbD4_RS11705	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AbD4_RS11710	COG0243	molybdopterin cofactor binding
AbD4_RS11720	COG0243	molybdopterin cofactor binding
AbD4_RS11725	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AbD4_RS11730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AbD4_RS11730	COG2146	nitrite reductase [NAD(P)H] activity
AbD4_RS11740	COG0745	RESPONSE REGULATOR receiver
AbD4_RS11745	COG1116	anion transmembrane transporter activity
AbD4_RS11745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AbD4_RS11765	COG0511	ligase activity, forming carbon-carbon bonds
AbD4_RS11780	COG2814	Major facilitator Superfamily
AbD4_RS11855	COG2314	TM2 domain
AbD4_RS11925	COG3566	protein conserved in bacteria
AbD4_RS11945	COG3567	Phage-associated protein, HI1409 family
AbD4_RS11950	COG5410	chromosome segregation
AbD4_RS12035	COG4197	protein conserved in bacteria, prophage-related
AbD4_RS12040	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AbD4_RS12115	COG0069	glutamate synthase activity
AbD4_RS12135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AbD4_RS12145	COG1454	alcohol dehydrogenase
AbD4_RS12150	COG0824	Thioesterase
AbD4_RS12160	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AbD4_RS12185	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AbD4_RS12190	COG2030	dehydratase
AbD4_RS12200	COG0183	Belongs to the thiolase family
AbD4_RS12210	COG0583	DNA-binding transcription factor activity
AbD4_RS12215	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AbD4_RS12225	COG1522	sequence-specific DNA binding
AbD4_RS12230	COG3135	benzoate transporter
AbD4_RS12240	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AbD4_RS12265	COG0589	response to stress
AbD4_RS12270	COG0488	(ABC) transporter
AbD4_RS12290	COG4773	Receptor
AbD4_RS12320	COG0668	transmembrane transport
AbD4_RS12360	COG0583	DNA-binding transcription factor activity
AbD4_RS12365	COG2814	Major facilitator Superfamily
AbD4_RS12370	COG2814	Major facilitator Superfamily
AbD4_RS12375	COG0446	pyridine nucleotide-disulphide oxidoreductase
AbD4_RS12380	COG3384	dioxygenase
AbD4_RS12385	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS12395	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
AbD4_RS12400	COG4638	Rieske (2fe-2S)
AbD4_RS12405	COG0583	DNA-binding transcription factor activity
AbD4_RS12425	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AbD4_RS12430	COG3971	2-oxopent-4-enoate hydratase activity
AbD4_RS12440	COG2271	Major facilitator Superfamily
AbD4_RS12445	COG1234	tRNA 3'-trailer cleavage
AbD4_RS12455	COG2963	transposase activity
AbD4_RS12465	COG4372	Transposase
AbD4_RS12495	COG4372	Transposase
AbD4_RS12505	COG2963	transposase activity
AbD4_RS12510	COG2963	transposase activity
AbD4_RS12520	COG4372	Transposase
AbD4_RS12525	COG1538	Outer membrane efflux protein
AbD4_RS12545	COG2885	chlorophyll binding
AbD4_RS12545	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AbD4_RS12590	COG1605	Chorismate mutase
AbD4_RS12610	COG0308	aminopeptidase N
AbD4_RS12630	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
AbD4_RS12640	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AbD4_RS12645	COG1454	alcohol dehydrogenase
AbD4_RS12665	COG0531	amino acid
AbD4_RS12670	COG4303	Ethanolamine ammonia lyase large subunit
AbD4_RS12675	COG4302	ethanolamine ammonia-lyase activity
AbD4_RS12680	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AbD4_RS12680	COG0519	Catalyzes the synthesis of GMP from XMP
AbD4_RS12685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AbD4_RS12710	COG0697	spore germination
AbD4_RS12715	COG1923	regulation of RNA biosynthetic process
AbD4_RS12725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AbD4_RS12730	COG0802	atpase or kinase
AbD4_RS12750	COG1187	pseudouridine synthase activity
AbD4_RS12765	COG0583	DNA-binding transcription factor activity
AbD4_RS12780	COG2814	Major facilitator Superfamily
AbD4_RS12785	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AbD4_RS12810	COG0729	surface antigen
AbD4_RS12830	COG0174	glutamine synthetase
AbD4_RS12835	COG0745	RESPONSE REGULATOR receiver
AbD4_RS12840	COG2205	protein histidine kinase activity
AbD4_RS12850	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AbD4_RS12880	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AbD4_RS12885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AbD4_RS12890	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS12920	COG0583	DNA-binding transcription factor activity
AbD4_RS12935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AbD4_RS12945	COG3658	cytochrome
AbD4_RS12950	COG1215	transferase activity, transferring glycosyl groups
AbD4_RS12955	COG0726	polysaccharide deacetylase
AbD4_RS12955	COG1649	PFAM Uncharacterised BCR, COG1649
AbD4_RS12965	COG2963	transposase activity
AbD4_RS12975	COG4372	Transposase
AbD4_RS13000	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AbD4_RS13005	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AbD4_RS13015	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
AbD4_RS13040	COG0305	Participates in initiation and elongation during chromosome replication
AbD4_RS13045	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AbD4_RS13055	COG1305	Transglutaminase-like
AbD4_RS13065	COG2308	Evidence 4 Homologs of previously reported genes of
AbD4_RS13095	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
AbD4_RS13100	COG0138	bifunctional purine biosynthesis protein purh
AbD4_RS13105	COG0151	Belongs to the GarS family
AbD4_RS13110	COG1464	Belongs to the NlpA lipoprotein family
AbD4_RS13115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AbD4_RS13120	COG2011	ABC-type metal ion transport system permease component
AbD4_RS13125	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AbD4_RS13140	COG2963	transposase activity
AbD4_RS13150	COG4372	Transposase
AbD4_RS13180	COG2814	Major facilitator Superfamily
AbD4_RS13195	COG1309	transcriptional regulator
AbD4_RS13215	COG1794	racemase activity, acting on amino acids and derivatives
AbD4_RS13220	COG3118	belongs to the thioredoxin family
AbD4_RS13220	COG0492	ferredoxin-NADP+ reductase activity
AbD4_RS13235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AbD4_RS13235	COG3008	intermembrane lipid transfer
AbD4_RS13240	COG2995	paraquat-inducible protein a
AbD4_RS13270	COG1051	belongs to the nudix hydrolase family
AbD4_RS13275	COG0477	Major facilitator Superfamily
AbD4_RS13325	COG2186	Transcriptional regulator
AbD4_RS13335	COG0786	glutamate:sodium symporter activity
AbD4_RS13340	COG3243	poly(R)-hydroxyalkanoic acid synthase
AbD4_RS13365	COG3111	PFAM Bacterial OB fold (BOF) protein
AbD4_RS13375	COG2226	methyltransferase
AbD4_RS13450	COG3210	domain, Protein
AbD4_RS13450	COG3210	domain, Protein
AbD4_RS13455	COG2831	hemolysin activation secretion protein
AbD4_RS13480	COG0515	serine threonine protein kinase
AbD4_RS13480	COG2815	serine threonine protein kinase
AbD4_RS13510	COG1610	YqeY-like protein
AbD4_RS13515	COG4783	chaperone-mediated protein folding
AbD4_RS13540	COG1286	toxin biosynthetic process
AbD4_RS13570	COG0778	Nitroreductase
AbD4_RS13580	COG0513	Belongs to the DEAD box helicase family
AbD4_RS13600	COG2363	Small membrane protein
AbD4_RS13630	COG4650	regulator
AbD4_RS13635	COG1234	tRNA 3'-trailer cleavage
AbD4_RS13640	COG1690	Belongs to the RtcB family
AbD4_RS13660	COG2195	Cleaves the N-terminal amino acid of tripeptides
AbD4_RS13670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AbD4_RS13680	COG2819	hydrolase of the alpha beta superfamily
AbD4_RS13685	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS13690	COG1301	dicarboxylic acid transport
AbD4_RS13695	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AbD4_RS13700	COG3139	Protein of unknown function (DUF1315)
AbD4_RS13705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AbD4_RS13710	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AbD4_RS13720	COG0494	nUDIX hydrolase
AbD4_RS13730	COG0642	Histidine kinase
AbD4_RS13745	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AbD4_RS13760	COG1720	tRNA m6t6A37 methyltransferase activity
AbD4_RS13775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AbD4_RS13780	COG0826	peptidase U32
AbD4_RS13785	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AbD4_RS13795	COG4598	ABC transporter
AbD4_RS13800	COG4160	amino acid transport
AbD4_RS13805	COG4215	(ABC) transporter
AbD4_RS13820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AbD4_RS14160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AbD4_RS14205	COG0582	viral genome integration into host DNA
AbD4_RS14210	COG1131	(ABC) transporter
AbD4_RS14215	COG0842	Transport permease protein
AbD4_RS14230	COG0772	Belongs to the SEDS family
AbD4_RS14235	COG2951	lytic endotransglycosylase activity
AbD4_RS14260	COG2963	transposase activity
AbD4_RS14270	COG4372	Transposase
AbD4_RS14280	COG2207	Transcriptional regulator
AbD4_RS14295	COG0052	Belongs to the universal ribosomal protein uS2 family
AbD4_RS14300	COG0024	Methionine aminopeptidase
AbD4_RS14310	COG2223	nitrite transmembrane transporter activity
AbD4_RS14320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AbD4_RS14325	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AbD4_RS14330	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS14345	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AbD4_RS14350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AbD4_RS14355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AbD4_RS14375	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AbD4_RS14380	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AbD4_RS14385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AbD4_RS14420	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AbD4_RS14430	COG0174	glutamine synthetase
AbD4_RS14445	COG0512	Glutamine amidotransferase of anthranilate synthase
AbD4_RS14450	COG0308	aminopeptidase N
AbD4_RS14470	COG2840	Smr protein MutS2
AbD4_RS14480	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AbD4_RS14490	COG0302	gtp cyclohydrolase
AbD4_RS14510	COG3739	integral membrane protein
AbD4_RS14525	COG1169	isochorismate synthase
AbD4_RS14530	COG2977	Belongs to the P-Pant transferase superfamily
AbD4_RS14535	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
AbD4_RS14540	COG1132	(ABC) transporter
AbD4_RS14545	COG1132	(ABC) transporter
AbD4_RS14555	COG1535	isochorismatase
AbD4_RS14555	COG3433	isochorismatase activity
AbD4_RS14560	COG1021	2,3-dihydroxybenzoate-AMP ligase
AbD4_RS14565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AbD4_RS14575	COG4774	siderophore transport
AbD4_RS14580	COG4607	ABC-type enterochelin transport system periplasmic component
AbD4_RS14585	COG4604	ABC transporter, ATP-binding protein
AbD4_RS14590	COG4605	iron ion homeostasis
AbD4_RS14595	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AbD4_RS14600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AbD4_RS14615	COG2964	Protein conserved in bacteria
AbD4_RS14625	COG1741	Belongs to the pirin family
AbD4_RS14665	COG2879	small protein
AbD4_RS14670	COG1966	Carbon starvation protein
AbD4_RS14690	COG4943	cyclic-guanylate-specific phosphodiesterase activity
AbD4_RS14710	COG2211	Major facilitator Superfamily
AbD4_RS14715	COG1067	ATP-dependent peptidase activity
AbD4_RS14720	COG0583	DNA-binding transcription factor activity
AbD4_RS14745	COG1686	Belongs to the peptidase S11 family
AbD4_RS14750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AbD4_RS14785	COG0616	signal peptide processing
AbD4_RS14790	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AbD4_RS14800	COG0573	inorganic phosphate transmembrane transporter activity
AbD4_RS14805	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AbD4_RS14810	COG1113	amino acid transport
AbD4_RS14815	COG3961	Belongs to the TPP enzyme family
AbD4_RS14820	COG1522	sequence-specific DNA binding
AbD4_RS14830	COG0076	glutamate decarboxylase activity
AbD4_RS14835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AbD4_RS14845	COG1309	transcriptional regulator
AbD4_RS14860	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AbD4_RS14895	COG0352	thiamine-phosphate diphosphorylase activity
AbD4_RS14920	COG1203	CRISPR-associated helicase, Cas3
AbD4_RS14950	COG0612	Peptidase, M16
AbD4_RS14960	COG1823	symporter activity
AbD4_RS14965	COG0583	DNA-binding transcription factor activity
AbD4_RS14970	COG0477	Major facilitator Superfamily
AbD4_RS14995	COG1187	pseudouridine synthase activity
AbD4_RS15010	COG1686	Belongs to the peptidase S11 family
AbD4_RS15015	COG1252	NADH dehydrogenase
AbD4_RS15025	COG0415	Belongs to the DNA photolyase family
AbD4_RS15040	COG1215	transferase activity, transferring glycosyl groups
AbD4_RS15070	COG2070	2-Nitropropane dioxygenase
AbD4_RS15125	COG0556	nucleotide-excision repair
AbD4_RS15145	COG0436	Aminotransferase
AbD4_RS15175	COG4221	oxidoreductase activity
AbD4_RS15185	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AbD4_RS15190	COG1381	Involved in DNA repair and RecF pathway recombination
AbD4_RS15200	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AbD4_RS15215	COG0681	Belongs to the peptidase S26 family
AbD4_RS15230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AbD4_RS15250	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AbD4_RS15255	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AbD4_RS15260	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AbD4_RS15270	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AbD4_RS15275	COG4208	sulfate ABC transporter
AbD4_RS15280	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AbD4_RS15285	COG0583	DNA-binding transcription factor activity
AbD4_RS15290	COG4625	pathogenesis
AbD4_RS15305	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AbD4_RS15320	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AbD4_RS15330	COG1051	belongs to the nudix hydrolase family
AbD4_RS15330	COG1056	cytidyltransferase-related domain
AbD4_RS15335	COG1024	Enoyl-CoA hydratase
AbD4_RS15345	COG2814	Major facilitator Superfamily
AbD4_RS15350	COG0047	phosphoribosylformylglycinamidine synthase activity
AbD4_RS15350	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AbD4_RS15370	COG1473	amidohydrolase
AbD4_RS15375	COG0824	Thioesterase
AbD4_RS15395	COG0823	Involved in the tonB-independent uptake of proteins
AbD4_RS15415	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AbD4_RS15440	COG2963	transposase activity
AbD4_RS15450	COG4372	Transposase
AbD4_RS15470	COG0628	permease
AbD4_RS15480	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AbD4_RS15485	COG0596	Alpha beta hydrolase
AbD4_RS15490	COG0616	signal peptide processing
AbD4_RS15490	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AbD4_RS15500	COG2333	competence protein COMEC
AbD4_RS15500	COG0658	competence protein
AbD4_RS15505	COG1136	(ABC) transporter
AbD4_RS15510	COG4591	ABC-type transport system involved in lipoprotein release permease component
AbD4_RS15545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AbD4_RS15565	COG0463	Glycosyl transferase, family 2
AbD4_RS15595	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AbD4_RS15600	COG1280	lysine exporter protein (LysE YggA)
AbD4_RS15610	COG0019	diaminopimelate decarboxylase activity
AbD4_RS15620	COG1113	amino acid transport
AbD4_RS15635	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AbD4_RS15645	COG3339	Conserved Protein
AbD4_RS15650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AbD4_RS15655	COG0243	molybdopterin cofactor binding
AbD4_RS15660	COG1929	Belongs to the glycerate kinase type-1 family
AbD4_RS15675	COG0778	Nitroreductase
AbD4_RS15705	COG3811	Belongs to the UPF0386 family
AbD4_RS15715	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AbD4_RS15730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AbD4_RS15750	COG0741	lytic transglycosylase activity
AbD4_RS15770	COG0584	glycerophosphoryl diester phosphodiesterase
AbD4_RS15795	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AbD4_RS15800	COG1597	lipid kinase activity
AbD4_RS15815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AbD4_RS15820	COG0477	Major facilitator Superfamily
AbD4_RS15870	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AbD4_RS15875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AbD4_RS15900	COG0505	Belongs to the CarA family
AbD4_RS15920	COG0589	response to stress
AbD4_RS15935	COG2843	Capsule synthesis protein
AbD4_RS15945	COG4372	Transposase
AbD4_RS15955	COG2963	transposase activity
AbD4_RS15975	COG2321	neutral zinc metallopeptidase
AbD4_RS15980	COG2354	Protein conserved in bacteria
AbD4_RS16000	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AbD4_RS16025	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AbD4_RS16030	COG1053	succinate dehydrogenase
AbD4_RS16035	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AbD4_RS16040	COG2009	succinate dehydrogenase
AbD4_RS16075	COG2921	Belongs to the UPF0250 family
AbD4_RS16080	COG0321	lipoyl(octanoyl) transferase activity
AbD4_RS16095	COG0531	amino acid
AbD4_RS16105	COG1733	regulation of RNA biosynthetic process
AbD4_RS16110	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
AbD4_RS16115	COG1648	precorrin-2 dehydrogenase activity
AbD4_RS16115	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AbD4_RS16130	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AbD4_RS16160	COG0671	phosphoesterase, PA-phosphatase related
AbD4_RS16165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AbD4_RS16175	COG1538	Outer membrane efflux protein
AbD4_RS16180	COG0393	Putative heavy-metal-binding
AbD4_RS16185	COG0393	Putative heavy-metal-binding
AbD4_RS16195	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS16205	COG0525	valine-tRNA ligase activity
AbD4_RS16225	COG0583	DNA-binding transcription factor activity
AbD4_RS16230	COG0004	ammonium transporteR
AbD4_RS16240	COG0642	Histidine kinase
AbD4_RS16245	COG0745	RESPONSE REGULATOR receiver
AbD4_RS16255	COG2963	transposase activity
AbD4_RS16265	COG4372	Transposase
AbD4_RS16285	COG1752	Esterase of the alpha-beta hydrolase superfamily
AbD4_RS16300	COG2315	Protein conserved in bacteria
AbD4_RS16305	COG0142	geranyltranstransferase activity
AbD4_RS16310	COG2828	Protein conserved in bacteria
AbD4_RS16315	COG1113	amino acid transport
AbD4_RS16335	COG2207	Transcriptional regulator
AbD4_RS16360	COG2249	NAD(P)H dehydrogenase (quinone) activity
AbD4_RS16370	COG0560	Phosphoserine phosphatase
AbD4_RS16380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AbD4_RS16390	COG1530	ribonuclease E activity
AbD4_RS16395	COG0424	maF-like protein
AbD4_RS16400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AbD4_RS16405	COG1792	Involved in formation and maintenance of cell shape
AbD4_RS16410	COG1077	Cell shape determining protein MreB Mrl
AbD4_RS16415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AbD4_RS16425	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AbD4_RS16450	COG3590	peptidase
AbD4_RS16455	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
AbD4_RS16460	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AbD4_RS16465	COG1752	Esterase of the alpha-beta hydrolase superfamily
AbD4_RS16470	COG1115	amino acid carrier protein
AbD4_RS16490	COG2814	Major facilitator Superfamily
AbD4_RS16495	COG1289	transmembrane transporter activity
AbD4_RS16505	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AbD4_RS16545	COG1376	ErfK ybiS ycfS ynhG family protein
AbD4_RS16550	COG2832	Protein of unknown function (DUF454)
AbD4_RS16560	COG5510	response to toxic substance
AbD4_RS16580	COG0840	transmembrane signaling receptor activity
AbD4_RS16620	COG3422	double-strand break repair
AbD4_RS16625	COG2824	Alkylphosphonate utilization operon protein PhnA
AbD4_RS16630	COG3189	MarR family transcriptional regulator
AbD4_RS16640	COG0354	folic acid binding
AbD4_RS16645	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AbD4_RS16655	COG0679	Auxin Efflux Carrier
AbD4_RS16660	COG1902	pentaerythritol trinitrate reductase activity
AbD4_RS16665	COG4772	TonB-dependent receptor
AbD4_RS16670	COG2094	Belongs to the DNA glycosylase MPG family
AbD4_RS16695	COG1217	gtp-binding protein TYPA
AbD4_RS16700	COG2233	PERMEase
AbD4_RS16710	COG0833	amino acid
AbD4_RS16715	COG1690	Belongs to the RtcB family
AbD4_RS16725	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AbD4_RS16725	COG2885	chlorophyll binding
AbD4_RS16735	COG0183	Belongs to the thiolase family
AbD4_RS16755	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AbD4_RS16775	COG2207	Transcriptional regulator
AbD4_RS16780	COG0183	Belongs to the thiolase family
AbD4_RS16800	COG2153	protein acetylation
AbD4_RS16810	COG1272	protein, Hemolysin III
AbD4_RS16815	COG0477	Major facilitator Superfamily
AbD4_RS16830	COG0450	alkyl hydroperoxide reductase
AbD4_RS16850	COG0285	dihydrofolate synthase activity
AbD4_RS16900	COG2096	Adenosyltransferase
AbD4_RS16920	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
AbD4_RS16925	COG0745	RESPONSE REGULATOR receiver
AbD4_RS16930	COG2205	protein histidine kinase activity
AbD4_RS16940	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS16945	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS16995	COG1442	glycosyl transferase family 8
AbD4_RS17010	COG0438	transferase activity, transferring glycosyl groups
AbD4_RS17020	COG0438	transferase activity, transferring glycosyl groups
AbD4_RS17025	COG0726	polysaccharide deacetylase
AbD4_RS17040	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AbD4_RS17045	COG2205	protein histidine kinase activity
AbD4_RS17075	COG1862	Preprotein translocase
AbD4_RS17085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AbD4_RS17090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AbD4_RS17100	COG3781	membrane
AbD4_RS17105	COG0613	PHP domain protein
AbD4_RS17115	COG2350	Protein conserved in bacteria
AbD4_RS17145	COG1607	acyl-coa hydrolase
AbD4_RS17205	COG2199	diguanylate cyclase activity
AbD4_RS17215	COG1408	metallophosphoesterase
AbD4_RS17220	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AbD4_RS17230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AbD4_RS17250	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AbD4_RS17255	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AbD4_RS17260	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AbD4_RS17270	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AbD4_RS17280	COG2969	positive regulation of protein catabolic process
AbD4_RS17300	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS17305	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AbD4_RS17320	COG1309	transcriptional regulator
AbD4_RS17325	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS17370	COG1183	phosphatidylcholine synthase activity
AbD4_RS17375	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AbD4_RS17405	COG0741	lytic transglycosylase activity
AbD4_RS17405	COG0739	heme binding
AbD4_RS17405	COG1196	nuclear chromosome segregation
AbD4_RS17415	COG1702	phosphate starvation-inducible protein PhoH
AbD4_RS17450	COG1295	ribonuclease BN
AbD4_RS17455	COG0697	spore germination
AbD4_RS17460	COG2169	Transcriptional regulator
AbD4_RS17465	COG0179	Fumarylacetoacetate (FAA) hydrolase
AbD4_RS17515	COG0557	exoribonuclease II activity
AbD4_RS17520	COG0339	signal peptide processing
AbD4_RS17525	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
AbD4_RS17555	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AbD4_RS17560	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS17715	COG0626	cystathionine gamma-synthase activity
AbD4_RS17720	COG0433	COG0433 Predicted ATPase
AbD4_RS17730	COG1017	nitric oxide dioxygenase activity
AbD4_RS17730	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AbD4_RS17735	COG1959	2 iron, 2 sulfur cluster binding
AbD4_RS17750	COG1301	dicarboxylic acid transport
AbD4_RS17755	COG1946	Acyl-CoA thioesterase
AbD4_RS17775	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AbD4_RS17780	COG1040	competence protein
AbD4_RS17785	COG0494	nUDIX hydrolase
AbD4_RS17795	COG0598	Magnesium transport protein CorA
AbD4_RS17805	COG2854	intermembrane phospholipid transfer
AbD4_RS17815	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AbD4_RS17820	COG1127	ABC transporter
AbD4_RS17830	COG0513	Belongs to the DEAD box helicase family
AbD4_RS17850	COG0408	coproporphyrinogen oxidase activity
AbD4_RS17865	COG1960	acyl-CoA dehydrogenase activity
AbD4_RS17875	COG1983	PspC domain protein
AbD4_RS17880	COG0517	IMP dehydrogenase activity
AbD4_RS17915	COG1106	Psort location Cytoplasmic, score
AbD4_RS17935	COG0583	DNA-binding transcription factor activity
AbD4_RS17975	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS17985	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AbD4_RS17990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AbD4_RS17995	COG0833	amino acid
AbD4_RS18025	COG1192	Involved in chromosome partitioning
AbD4_RS18030	COG0628	permease
AbD4_RS18040	COG1289	transmembrane transporter activity
AbD4_RS18055	COG2249	NAD(P)H dehydrogenase (quinone) activity
AbD4_RS18060	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
AbD4_RS18070	COG0277	FAD linked oxidase domain protein
AbD4_RS18075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AbD4_RS18100	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AbD4_RS18105	COG5380	lipid catabolic process
AbD4_RS18125	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AbD4_RS18175	COG0194	GDP metabolic process
AbD4_RS18190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AbD4_RS18210	COG3307	-O-antigen
AbD4_RS18225	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
AbD4_RS18230	COG1704	LemA family
AbD4_RS18240	COG0493	'glutamate synthase
AbD4_RS18245	COG0067	glutamate synthase
AbD4_RS18245	COG0069	glutamate synthase activity
AbD4_RS18245	COG0070	glutamate synthase
AbD4_RS18295	COG2226	methyltransferase
AbD4_RS18310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AbD4_RS18315	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AbD4_RS18360	COG0833	amino acid
AbD4_RS18425	COG0488	(ABC) transporter
AbD4_RS18430	COG2873	o-acetylhomoserine
AbD4_RS18435	COG4221	oxidoreductase activity
AbD4_RS18440	COG0659	secondary active sulfate transmembrane transporter activity
AbD4_RS18465	COG0427	acetyl-CoA hydrolase
AbD4_RS18495	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AbD4_RS18530	COG2329	Antibiotic biosynthesis monooxygenase
AbD4_RS18545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AbD4_RS18615	COG2249	NAD(P)H dehydrogenase (quinone) activity
AbD4_RS18620	COG1733	regulation of RNA biosynthetic process
AbD4_RS18650	COG1733	regulation of RNA biosynthetic process
AbD4_RS18670	COG0667	Aldo Keto reductase
AbD4_RS18690	COG0583	DNA-binding transcription factor activity
AbD4_RS18695	COG2814	Major facilitator Superfamily
AbD4_RS18725	COG1335	isochorismatase
AbD4_RS18735	COG1012	belongs to the aldehyde dehydrogenase family
AbD4_RS18740	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AbD4_RS18750	COG1113	amino acid transport
AbD4_RS18760	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AbD4_RS18775	COG2814	Major facilitator Superfamily
AbD4_RS18785	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AbD4_RS18785	COG0352	thiamine-phosphate diphosphorylase activity
AbD4_RS18785	COG0351	phosphomethylpyrimidine kinase
AbD4_RS18805	COG1309	transcriptional regulator
AbD4_RS18825	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
AbD4_RS18835	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AbD4_RS18840	COG3162	membrane
AbD4_RS18845	COG2205	protein histidine kinase activity
AbD4_RS18845	COG0784	Response regulator, receiver
AbD4_RS18845	COG2198	Histidine kinase
AbD4_RS18870	COG1522	sequence-specific DNA binding
AbD4_RS18875	COG1335	isochorismatase
AbD4_RS18880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AbD4_RS18890	COG0668	transmembrane transport
AbD4_RS18895	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AbD4_RS18900	COG1519	Transferase
AbD4_RS18905	COG1902	pentaerythritol trinitrate reductase activity
AbD4_RS18930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AbD4_RS18955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AbD4_RS18955	COG0426	domain, Protein
AbD4_RS18960	COG4774	siderophore transport
AbD4_RS18965	COG2119	membrane
AbD4_RS18975	COG0508	dehydrogenase complex catalyzes the overall conversion of
AbD4_RS18985	COG4942	peptidase
AbD4_RS19000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AbD4_RS19010	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AbD4_RS19030	COG0189	ligase activity
AbD4_RS19055	COG0708	Exodeoxyribonuclease III
AbD4_RS19060	COG1393	Belongs to the ArsC family
AbD4_RS19075	COG3706	GGDEF domain
AbD4_RS19110	COG2351	hydroxyisourate hydrolase activity
AbD4_RS19115	COG2233	PERMEase
AbD4_RS19125	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AbD4_RS19135	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
AbD4_RS19140	COG1028	Short-chain dehydrogenase reductase Sdr
AbD4_RS19150	COG3150	esterase
AbD4_RS19195	COG1388	LysM domain
AbD4_RS19195	COG3409	Peptidoglycan-binding domain 1 protein
AbD4_RS19195	COG5632	N-Acetylmuramoyl-L-alanine amidase
AbD4_RS19210	COG2918	glutathione biosynthetic process
AbD4_RS19225	COG2733	membrane
AbD4_RS19230	COG0436	Aminotransferase
AbD4_RS19235	COG0534	Mate efflux family protein
AbD4_RS19320	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AbD4_RS19325	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AbD4_RS19335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AbD4_RS19385	COG4372	Transposase
AbD4_RS19395	COG2963	transposase activity
AbD4_RS19410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AbD4_RS19425	COG0534	Mate efflux family protein
AbD4_RS19470	COG1271	oxidase subunit
AbD4_RS19475	COG1294	oxidase, subunit
AbD4_RS19505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AbD4_RS19535	COG0523	cobalamin synthesis protein
AbD4_RS19550	COG0215	cysteine-tRNA ligase activity
AbD4_RS19560	COG1469	GTP cyclohydrolase I activity
AbD4_RS19565	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AbD4_RS19570	COG4451	ribulose bisphosphate carboxylase, small
AbD4_RS19570	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AbD4_RS19575	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AbD4_RS19580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AbD4_RS19595	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AbD4_RS19600	COG0546	phosphoglycolate phosphatase activity
AbD4_RS19610	COG0010	Belongs to the arginase family
AbD4_RS19640	COG2188	Transcriptional regulator
AbD4_RS19650	COG0523	cobalamin synthesis protein
AbD4_RS19660	COG1113	amino acid transport
AbD4_RS19670	COG0625	glutathione transferase activity
AbD4_RS19690	COG1683	Conserved Protein
AbD4_RS19695	COG0534	Mate efflux family protein
AbD4_RS19700	COG0385	Bile acid
AbD4_RS19705	COG1335	isochorismatase
AbD4_RS19710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AbD4_RS19730	COG2116	formate transmembrane transporter activity
AbD4_RS19735	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AbD4_RS19740	COG2133	pyrroloquinoline quinone binding
AbD4_RS19745	COG2983	Belongs to the UPF0260 family
AbD4_RS19765	COG1194	a g-specific adenine glycosylase
AbD4_RS19790	COG2818	Glycosylase
AbD4_RS19795	COG1064	alcohol dehydrogenase
AbD4_RS19800	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AbD4_RS19815	COG0583	DNA-binding transcription factor activity
AbD4_RS19820	COG0656	L-ascorbic acid biosynthetic process
AbD4_RS19825	COG2814	Major facilitator Superfamily
AbD4_RS19860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AbD4_RS19875	COG2233	PERMEase
AbD4_RS19880	COG0583	DNA-binding transcription factor activity
AbD4_RS19915	COG0733	neurotransmitter:sodium symporter activity
AbD4_RS19960	COG1192	Involved in chromosome partitioning
AbD4_RS19970	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AbD4_RS20010	COG0739	heme binding
AbD4_RS20065	COG2963	transposase activity
AbD4_RS20075	COG4372	Transposase
AbD4_RS20190	COG2963	transposase activity
AbD4_RS20200	COG4372	Transposase
AbD4_RS20255	COG4372	Transposase
AbD4_RS20265	COG2963	transposase activity
AbD4_RS20290	COG0501	Belongs to the peptidase M48B family
AbD4_RS20325	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
AbD4_RS20405	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AbD4_RS20420	COG2963	transposase activity
AbD4_RS20430	COG4372	Transposase
AbD4_RS20610	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB