locus-tag	class	description
LO010_RS00020	COG0592	DNA-directed DNA polymerase activity
LO010_RS00030	COG0187	DNA topoisomerase II activity
LO010_RS00040	COG0586	Pfam SNARE associated Golgi protein
LO010_RS00045	COG0488	(ABC) transporter
LO010_RS00075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LO010_RS00080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LO010_RS00125	COG0733	neurotransmitter:sodium symporter activity
LO010_RS00160	COG0583	DNA-binding transcription factor activity
LO010_RS00165	COG2233	PERMEase
LO010_RS00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO010_RS00215	COG2814	Major facilitator Superfamily
LO010_RS00220	COG0656	L-ascorbic acid biosynthetic process
LO010_RS00225	COG0583	DNA-binding transcription factor activity
LO010_RS00240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO010_RS00245	COG1064	alcohol dehydrogenase
LO010_RS00250	COG2818	Glycosylase
LO010_RS00265	COG1194	a g-specific adenine glycosylase
LO010_RS00285	COG2983	Belongs to the UPF0260 family
LO010_RS00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LO010_RS00300	COG2116	formate transmembrane transporter activity
LO010_RS00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO010_RS00325	COG1335	isochorismatase
LO010_RS00330	COG0385	Bile acid
LO010_RS00335	COG0534	Mate efflux family protein
LO010_RS00340	COG1683	Conserved Protein
LO010_RS00360	COG0625	glutathione transferase activity
LO010_RS00370	COG1113	amino acid transport
LO010_RS00380	COG0523	cobalamin synthesis protein
LO010_RS00390	COG2188	Transcriptional regulator
LO010_RS00420	COG0010	Belongs to the arginase family
LO010_RS00435	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LO010_RS00445	COG2963	transposase activity
LO010_RS00455	COG4372	Transposase
LO010_RS00485	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
LO010_RS00490	COG0732	type I restriction modification DNA specificity domain
LO010_RS00530	COG4584	PFAM Integrase catalytic
LO010_RS00540	COG1484	DNA-dependent DNA replication
LO010_RS00550	COG1484	DNA-dependent DNA replication
LO010_RS00585	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LO010_RS00625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LO010_RS00635	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LO010_RS00640	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LO010_RS00740	COG0534	Mate efflux family protein
LO010_RS00745	COG0436	Aminotransferase
LO010_RS00750	COG2733	membrane
LO010_RS00765	COG2918	glutathione biosynthetic process
LO010_RS00795	COG3150	esterase
LO010_RS00805	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS00810	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LO010_RS00820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO010_RS00830	COG2233	PERMEase
LO010_RS00835	COG2351	hydroxyisourate hydrolase activity
LO010_RS00870	COG3706	GGDEF domain
LO010_RS00885	COG1393	Belongs to the ArsC family
LO010_RS00890	COG0708	Exodeoxyribonuclease III
LO010_RS00910	COG0189	ligase activity
LO010_RS00930	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LO010_RS00940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LO010_RS00955	COG4942	peptidase
LO010_RS00965	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO010_RS00975	COG2119	membrane
LO010_RS00980	COG4774	siderophore transport
LO010_RS00985	COG0426	domain, Protein
LO010_RS00985	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO010_RS01010	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LO010_RS01030	COG1902	pentaerythritol trinitrate reductase activity
LO010_RS01035	COG1519	Transferase
LO010_RS01040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LO010_RS01045	COG0668	transmembrane transport
LO010_RS01055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO010_RS01060	COG1335	isochorismatase
LO010_RS01065	COG1522	sequence-specific DNA binding
LO010_RS01090	COG0784	Response regulator, receiver
LO010_RS01090	COG2198	Histidine kinase
LO010_RS01090	COG2205	protein histidine kinase activity
LO010_RS01095	COG3162	membrane
LO010_RS01100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LO010_RS01110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LO010_RS01130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LO010_RS01135	COG1309	transcriptional regulator
LO010_RS01155	COG0352	thiamine-phosphate diphosphorylase activity
LO010_RS01155	COG0351	phosphomethylpyrimidine kinase
LO010_RS01155	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LO010_RS01165	COG2814	Major facilitator Superfamily
LO010_RS01180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LO010_RS01190	COG1113	amino acid transport
LO010_RS01200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LO010_RS01205	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS01215	COG1335	isochorismatase
LO010_RS01245	COG2814	Major facilitator Superfamily
LO010_RS01250	COG0583	DNA-binding transcription factor activity
LO010_RS01270	COG0667	Aldo Keto reductase
LO010_RS01305	COG1733	regulation of RNA biosynthetic process
LO010_RS01310	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO010_RS01375	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LO010_RS01390	COG2329	Antibiotic biosynthesis monooxygenase
LO010_RS01420	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LO010_RS01450	COG0427	acetyl-CoA hydrolase
LO010_RS01475	COG0659	secondary active sulfate transmembrane transporter activity
LO010_RS01480	COG4221	oxidoreductase activity
LO010_RS01485	COG2873	o-acetylhomoserine
LO010_RS01490	COG0488	(ABC) transporter
LO010_RS01575	COG0833	amino acid
LO010_RS01620	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LO010_RS01625	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LO010_RS01640	COG2226	methyltransferase
LO010_RS01690	COG0070	glutamate synthase
LO010_RS01690	COG0069	glutamate synthase activity
LO010_RS01690	COG0067	glutamate synthase
LO010_RS01695	COG0493	'glutamate synthase
LO010_RS01705	COG1704	LemA family
LO010_RS01710	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LO010_RS01725	COG3307	-O-antigen
LO010_RS01745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LO010_RS01760	COG0194	GDP metabolic process
LO010_RS01820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LO010_RS01840	COG5380	lipid catabolic process
LO010_RS01845	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LO010_RS01870	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LO010_RS01875	COG0277	FAD linked oxidase domain protein
LO010_RS01885	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LO010_RS01890	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO010_RS01905	COG1289	transmembrane transporter activity
LO010_RS01915	COG0628	permease
LO010_RS01920	COG1192	Involved in chromosome partitioning
LO010_RS01950	COG0833	amino acid
LO010_RS01955	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LO010_RS01960	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LO010_RS01970	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS02010	COG0583	DNA-binding transcription factor activity
LO010_RS02060	COG0517	IMP dehydrogenase activity
LO010_RS02065	COG1983	PspC domain protein
LO010_RS02075	COG1960	acyl-CoA dehydrogenase activity
LO010_RS02090	COG0408	coproporphyrinogen oxidase activity
LO010_RS02110	COG0513	Belongs to the DEAD box helicase family
LO010_RS02120	COG1127	ABC transporter
LO010_RS02125	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LO010_RS02135	COG2854	intermembrane phospholipid transfer
LO010_RS02145	COG0598	Magnesium transport protein CorA
LO010_RS02155	COG0494	nUDIX hydrolase
LO010_RS02160	COG1040	competence protein
LO010_RS02165	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LO010_RS02185	COG1946	Acyl-CoA thioesterase
LO010_RS02190	COG1301	dicarboxylic acid transport
LO010_RS02205	COG1959	2 iron, 2 sulfur cluster binding
LO010_RS02210	COG1017	nitric oxide dioxygenase activity
LO010_RS02210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO010_RS02220	COG0433	COG0433 Predicted ATPase
LO010_RS02225	COG0626	cystathionine gamma-synthase activity
LO010_RS02380	COG1960	acyl-CoA dehydrogenase activity
LO010_RS02385	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LO010_RS02415	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LO010_RS02420	COG0339	signal peptide processing
LO010_RS02425	COG0557	exoribonuclease II activity
LO010_RS02470	COG0179	Fumarylacetoacetate (FAA) hydrolase
LO010_RS02475	COG2169	Transcriptional regulator
LO010_RS02480	COG0697	spore germination
LO010_RS02485	COG1295	ribonuclease BN
LO010_RS02520	COG1702	phosphate starvation-inducible protein PhoH
LO010_RS02530	COG1196	nuclear chromosome segregation
LO010_RS02530	COG0741	lytic transglycosylase activity
LO010_RS02530	COG0739	heme binding
LO010_RS02560	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LO010_RS02565	COG1183	phosphatidylcholine synthase activity
LO010_RS02610	COG1960	acyl-CoA dehydrogenase activity
LO010_RS02615	COG1309	transcriptional regulator
LO010_RS02630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LO010_RS02635	COG1960	acyl-CoA dehydrogenase activity
LO010_RS02675	COG2969	positive regulation of protein catabolic process
LO010_RS02685	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LO010_RS02695	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LO010_RS02700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LO010_RS02705	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LO010_RS02725	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LO010_RS02735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LO010_RS02740	COG1408	metallophosphoesterase
LO010_RS02750	COG2199	diguanylate cyclase activity
LO010_RS02820	COG1607	acyl-coa hydrolase
LO010_RS02850	COG2350	Protein conserved in bacteria
LO010_RS02860	COG0613	PHP domain protein
LO010_RS02865	COG3781	membrane
LO010_RS02875	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LO010_RS02880	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LO010_RS02890	COG1862	Preprotein translocase
LO010_RS02940	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO010_RS02945	COG0629	single-stranded DNA binding
LO010_RS02995	COG3646	Phage regulatory protein
LO010_RS03005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LO010_RS03140	COG4695	Portal protein
LO010_RS03145	COG2205	protein histidine kinase activity
LO010_RS03150	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LO010_RS03165	COG0726	polysaccharide deacetylase
LO010_RS03170	COG0438	transferase activity, transferring glycosyl groups
LO010_RS03185	COG1091	dTDP-4-dehydrorhamnose reductase activity
LO010_RS03200	COG1215	transferase activity, transferring glycosyl groups
LO010_RS03250	COG1960	acyl-CoA dehydrogenase activity
LO010_RS03255	COG1960	acyl-CoA dehydrogenase activity
LO010_RS03265	COG2205	protein histidine kinase activity
LO010_RS03270	COG0745	RESPONSE REGULATOR receiver
LO010_RS03275	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LO010_RS03295	COG2096	Adenosyltransferase
LO010_RS03345	COG0285	dihydrofolate synthase activity
LO010_RS03365	COG0450	alkyl hydroperoxide reductase
LO010_RS03380	COG0477	Major facilitator Superfamily
LO010_RS03385	COG1272	protein, Hemolysin III
LO010_RS03405	COG2153	protein acetylation
LO010_RS03425	COG0183	Belongs to the thiolase family
LO010_RS03430	COG2207	Transcriptional regulator
LO010_RS03450	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO010_RS03470	COG0183	Belongs to the thiolase family
LO010_RS03480	COG2885	chlorophyll binding
LO010_RS03480	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LO010_RS03490	COG1690	Belongs to the RtcB family
LO010_RS03495	COG0833	amino acid
LO010_RS03505	COG2233	PERMEase
LO010_RS03510	COG1217	gtp-binding protein TYPA
LO010_RS03535	COG2094	Belongs to the DNA glycosylase MPG family
LO010_RS03540	COG4772	TonB-dependent receptor
LO010_RS03545	COG1902	pentaerythritol trinitrate reductase activity
LO010_RS03560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO010_RS03565	COG0354	folic acid binding
LO010_RS03575	COG3189	MarR family transcriptional regulator
LO010_RS03580	COG2824	Alkylphosphonate utilization operon protein PhnA
LO010_RS03585	COG3422	double-strand break repair
LO010_RS03625	COG0840	transmembrane signaling receptor activity
LO010_RS03640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LO010_RS03655	COG5510	response to toxic substance
LO010_RS03665	COG2832	Protein of unknown function (DUF454)
LO010_RS03670	COG1376	ErfK ybiS ycfS ynhG family protein
LO010_RS03710	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LO010_RS03720	COG1289	transmembrane transporter activity
LO010_RS03725	COG2814	Major facilitator Superfamily
LO010_RS03745	COG1115	amino acid carrier protein
LO010_RS03750	COG1752	Esterase of the alpha-beta hydrolase superfamily
LO010_RS03755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LO010_RS03760	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LO010_RS03770	COG3590	peptidase
LO010_RS03795	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LO010_RS03805	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LO010_RS03810	COG1077	Cell shape determining protein MreB Mrl
LO010_RS03815	COG1792	Involved in formation and maintenance of cell shape
LO010_RS03820	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LO010_RS03825	COG0424	maF-like protein
LO010_RS03830	COG1530	ribonuclease E activity
LO010_RS03840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO010_RS03850	COG0560	Phosphoserine phosphatase
LO010_RS03860	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO010_RS03885	COG2207	Transcriptional regulator
LO010_RS03905	COG0464	growth
LO010_RS03950	COG0305	Participates in initiation and elongation during chromosome replication
LO010_RS03985	COG0582	viral genome integration into host DNA
LO010_RS03995	COG1113	amino acid transport
LO010_RS04000	COG2828	Protein conserved in bacteria
LO010_RS04005	COG0142	geranyltranstransferase activity
LO010_RS04010	COG2315	Protein conserved in bacteria
LO010_RS04025	COG1752	Esterase of the alpha-beta hydrolase superfamily
LO010_RS04045	COG2194	sulfuric ester hydrolase activity
LO010_RS04050	COG0745	RESPONSE REGULATOR receiver
LO010_RS04055	COG0642	Histidine kinase
LO010_RS04070	COG0004	ammonium transporteR
LO010_RS04090	COG2226	methyltransferase
LO010_RS04095	COG0525	valine-tRNA ligase activity
LO010_RS04105	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS04115	COG0393	Putative heavy-metal-binding
LO010_RS04120	COG0393	Putative heavy-metal-binding
LO010_RS04125	COG1538	Outer membrane efflux protein
LO010_RS04135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO010_RS04140	COG0671	phosphoesterase, PA-phosphatase related
LO010_RS04170	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LO010_RS04185	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LO010_RS04185	COG1648	precorrin-2 dehydrogenase activity
LO010_RS04190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LO010_RS04195	COG1733	regulation of RNA biosynthetic process
LO010_RS04205	COG0531	amino acid
LO010_RS04220	COG0321	lipoyl(octanoyl) transferase activity
LO010_RS04225	COG2921	Belongs to the UPF0250 family
LO010_RS04265	COG2009	succinate dehydrogenase
LO010_RS04270	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LO010_RS04275	COG1053	succinate dehydrogenase
LO010_RS04280	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LO010_RS04305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO010_RS04325	COG2354	Protein conserved in bacteria
LO010_RS04330	COG2321	neutral zinc metallopeptidase
LO010_RS04350	COG2843	Capsule synthesis protein
LO010_RS04365	COG0589	response to stress
LO010_RS04375	COG0251	oxidation-reduction process
LO010_RS04395	COG0505	Belongs to the CarA family
LO010_RS04420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LO010_RS04425	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LO010_RS04475	COG0477	Major facilitator Superfamily
LO010_RS04480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LO010_RS04495	COG1597	lipid kinase activity
LO010_RS04500	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LO010_RS04525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO010_RS04550	COG0741	lytic transglycosylase activity
LO010_RS04570	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LO010_RS04585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO010_RS04600	COG0789	Transcriptional regulator
LO010_RS04630	COG0778	Nitroreductase
LO010_RS04645	COG1929	Belongs to the glycerate kinase type-1 family
LO010_RS04650	COG0243	molybdopterin cofactor binding
LO010_RS04655	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LO010_RS04660	COG3339	Conserved Protein
LO010_RS04685	COG1115	amino acid carrier protein
LO010_RS04690	COG1113	amino acid transport
LO010_RS04700	COG0019	diaminopimelate decarboxylase activity
LO010_RS04710	COG2267	carboxylic ester hydrolase activity
LO010_RS04715	COG1280	lysine exporter protein (LysE YggA)
LO010_RS04720	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LO010_RS04750	COG0463	Glycosyl transferase, family 2
LO010_RS04770	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO010_RS04800	COG4591	ABC-type transport system involved in lipoprotein release permease component
LO010_RS04805	COG1136	(ABC) transporter
LO010_RS04810	COG2333	competence protein COMEC
LO010_RS04810	COG0658	competence protein
LO010_RS04820	COG0616	signal peptide processing
LO010_RS04820	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LO010_RS04825	COG0596	Alpha beta hydrolase
LO010_RS04830	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LO010_RS04840	COG0628	permease
LO010_RS04855	COG4372	Transposase
LO010_RS04865	COG2963	transposase activity
LO010_RS04895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LO010_RS04915	COG0823	Involved in the tonB-independent uptake of proteins
LO010_RS04935	COG0824	Thioesterase
LO010_RS04940	COG1473	amidohydrolase
LO010_RS04960	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LO010_RS04960	COG0047	phosphoribosylformylglycinamidine synthase activity
LO010_RS04965	COG2814	Major facilitator Superfamily
LO010_RS04980	COG1024	Enoyl-CoA hydratase
LO010_RS04985	COG1051	belongs to the nudix hydrolase family
LO010_RS04985	COG1056	cytidyltransferase-related domain
LO010_RS04995	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LO010_RS05010	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LO010_RS05025	COG4625	pathogenesis
LO010_RS05030	COG0583	DNA-binding transcription factor activity
LO010_RS05035	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LO010_RS05040	COG4208	sulfate ABC transporter
LO010_RS05045	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LO010_RS05055	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LO010_RS05060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LO010_RS05065	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LO010_RS05085	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO010_RS05100	COG0681	Belongs to the peptidase S26 family
LO010_RS05115	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LO010_RS05125	COG1381	Involved in DNA repair and RecF pathway recombination
LO010_RS05130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LO010_RS05140	COG4221	oxidoreductase activity
LO010_RS05170	COG0443	Heat shock 70 kDa protein
LO010_RS05180	COG0436	Aminotransferase
LO010_RS05200	COG0556	nucleotide-excision repair
LO010_RS05255	COG2070	2-Nitropropane dioxygenase
LO010_RS05285	COG1215	transferase activity, transferring glycosyl groups
LO010_RS05300	COG0415	Belongs to the DNA photolyase family
LO010_RS05310	COG1252	NADH dehydrogenase
LO010_RS05315	COG1686	Belongs to the peptidase S11 family
LO010_RS05330	COG1187	pseudouridine synthase activity
LO010_RS05355	COG0477	Major facilitator Superfamily
LO010_RS05360	COG0583	DNA-binding transcription factor activity
LO010_RS05365	COG1823	symporter activity
LO010_RS05375	COG0612	Peptidase, M16
LO010_RS05400	COG0352	thiamine-phosphate diphosphorylase activity
LO010_RS05435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO010_RS05445	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO010_RS05460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LO010_RS05465	COG0076	glutamate decarboxylase activity
LO010_RS05475	COG1522	sequence-specific DNA binding
LO010_RS05485	COG3961	Belongs to the TPP enzyme family
LO010_RS05490	COG1113	amino acid transport
LO010_RS05495	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LO010_RS05500	COG0573	inorganic phosphate transmembrane transporter activity
LO010_RS05510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LO010_RS05515	COG0616	signal peptide processing
LO010_RS05550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LO010_RS05555	COG1686	Belongs to the peptidase S11 family
LO010_RS05580	COG0583	DNA-binding transcription factor activity
LO010_RS05585	COG1067	ATP-dependent peptidase activity
LO010_RS05610	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LO010_RS05630	COG1966	Carbon starvation protein
LO010_RS05635	COG2879	small protein
LO010_RS05680	COG1741	Belongs to the pirin family
LO010_RS05690	COG2964	Protein conserved in bacteria
LO010_RS05705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO010_RS05710	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO010_RS05715	COG4605	iron ion homeostasis
LO010_RS05720	COG4604	ABC transporter, ATP-binding protein
LO010_RS05725	COG4607	ABC-type enterochelin transport system periplasmic component
LO010_RS05730	COG4774	siderophore transport
LO010_RS05740	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO010_RS05745	COG1021	2,3-dihydroxybenzoate-AMP ligase
LO010_RS05750	COG1535	isochorismatase
LO010_RS05750	COG3433	isochorismatase activity
LO010_RS05760	COG1132	(ABC) transporter
LO010_RS05765	COG1132	(ABC) transporter
LO010_RS05770	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LO010_RS05795	COG3739	integral membrane protein
LO010_RS05815	COG0302	gtp cyclohydrolase
LO010_RS05825	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LO010_RS05860	COG0512	Glutamine amidotransferase of anthranilate synthase
LO010_RS05875	COG0174	glutamine synthetase
LO010_RS05885	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LO010_RS05920	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LO010_RS05925	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LO010_RS05930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO010_RS05960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LO010_RS05965	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LO010_RS05970	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LO010_RS05985	COG1960	acyl-CoA dehydrogenase activity
LO010_RS05990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LO010_RS05995	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO010_RS06005	COG2223	nitrite transmembrane transporter activity
LO010_RS06015	COG0024	Methionine aminopeptidase
LO010_RS06020	COG0052	Belongs to the universal ribosomal protein uS2 family
LO010_RS06035	COG2207	Transcriptional regulator
LO010_RS06060	COG2951	lytic endotransglycosylase activity
LO010_RS06065	COG0772	Belongs to the SEDS family
LO010_RS06080	COG0842	Transport permease protein
LO010_RS06085	COG1131	(ABC) transporter
LO010_RS06130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO010_RS06145	COG4215	(ABC) transporter
LO010_RS06150	COG4160	amino acid transport
LO010_RS06155	COG4598	ABC transporter
LO010_RS06165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO010_RS06170	COG0826	peptidase U32
LO010_RS06175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO010_RS06190	COG1720	tRNA m6t6A37 methyltransferase activity
LO010_RS06200	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LO010_RS06215	COG0642	Histidine kinase
LO010_RS06225	COG0494	nUDIX hydrolase
LO010_RS06235	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LO010_RS06240	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LO010_RS06245	COG3139	Protein of unknown function (DUF1315)
LO010_RS06250	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LO010_RS06255	COG1301	dicarboxylic acid transport
LO010_RS06260	COG1960	acyl-CoA dehydrogenase activity
LO010_RS06265	COG2819	hydrolase of the alpha beta superfamily
LO010_RS06275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LO010_RS06285	COG2195	Cleaves the N-terminal amino acid of tripeptides
LO010_RS06290	COG1234	tRNA 3'-trailer cleavage
LO010_RS06330	COG2363	Small membrane protein
LO010_RS06355	COG0513	Belongs to the DEAD box helicase family
LO010_RS06365	COG0778	Nitroreductase
LO010_RS06395	COG1286	toxin biosynthetic process
LO010_RS06420	COG4783	chaperone-mediated protein folding
LO010_RS06425	COG1610	YqeY-like protein
LO010_RS06455	COG2815	serine threonine protein kinase
LO010_RS06455	COG0515	serine threonine protein kinase
LO010_RS06480	COG2831	hemolysin activation secretion protein
LO010_RS06505	COG4372	Transposase
LO010_RS06515	COG2963	transposase activity
LO010_RS06625	COG3111	PFAM Bacterial OB fold (BOF) protein
LO010_RS06650	COG3243	poly(R)-hydroxyalkanoic acid synthase
LO010_RS06655	COG0786	glutamate:sodium symporter activity
LO010_RS06665	COG2186	Transcriptional regulator
LO010_RS06715	COG0477	Major facilitator Superfamily
LO010_RS06720	COG1051	belongs to the nudix hydrolase family
LO010_RS06750	COG2985	domain, Protein
LO010_RS06765	COG2995	paraquat-inducible protein a
LO010_RS06770	COG3008	intermembrane lipid transfer
LO010_RS06770	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LO010_RS06780	COG2351	hydroxyisourate hydrolase activity
LO010_RS06820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LO010_RS06830	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LO010_RS06835	COG0642	Histidine kinase
LO010_RS06840	COG0745	RESPONSE REGULATOR receiver
LO010_RS06860	COG1794	racemase activity, acting on amino acids and derivatives
LO010_RS06890	COG1301	dicarboxylic acid transport
LO010_RS06900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO010_RS06905	COG2011	ABC-type metal ion transport system permease component
LO010_RS06910	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LO010_RS06915	COG1464	Belongs to the NlpA lipoprotein family
LO010_RS06920	COG0151	Belongs to the GarS family
LO010_RS06925	COG0138	bifunctional purine biosynthesis protein purh
LO010_RS06930	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LO010_RS06980	COG1305	Transglutaminase-like
LO010_RS06990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LO010_RS06995	COG0305	Participates in initiation and elongation during chromosome replication
LO010_RS07020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LO010_RS07030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LO010_RS07035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LO010_RS07060	COG1649	PFAM Uncharacterised BCR, COG1649
LO010_RS07060	COG0726	polysaccharide deacetylase
LO010_RS07065	COG1215	transferase activity, transferring glycosyl groups
LO010_RS07070	COG3658	cytochrome
LO010_RS07080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO010_RS07095	COG0583	DNA-binding transcription factor activity
LO010_RS07115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO010_RS07120	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO010_RS07135	COG1960	acyl-CoA dehydrogenase activity
LO010_RS07140	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO010_RS07145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO010_RS07170	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LO010_RS07175	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LO010_RS07185	COG2205	protein histidine kinase activity
LO010_RS07190	COG0745	RESPONSE REGULATOR receiver
LO010_RS07195	COG0174	glutamine synthetase
LO010_RS07215	COG0729	surface antigen
LO010_RS07240	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO010_RS07245	COG2814	Major facilitator Superfamily
LO010_RS07260	COG0583	DNA-binding transcription factor activity
LO010_RS07275	COG1187	pseudouridine synthase activity
LO010_RS07295	COG0802	atpase or kinase
LO010_RS07300	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LO010_RS07310	COG1923	regulation of RNA biosynthetic process
LO010_RS07315	COG0697	spore germination
LO010_RS07330	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LO010_RS07340	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LO010_RS07345	COG0519	Catalyzes the synthesis of GMP from XMP
LO010_RS07345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LO010_RS07350	COG4302	ethanolamine ammonia-lyase activity
LO010_RS07355	COG4303	Ethanolamine ammonia lyase large subunit
LO010_RS07360	COG0531	amino acid
LO010_RS07380	COG1454	alcohol dehydrogenase
LO010_RS07385	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LO010_RS07395	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LO010_RS07415	COG0308	aminopeptidase N
LO010_RS07455	COG1605	Chorismate mutase
LO010_RS07475	COG1309	transcriptional regulator
LO010_RS07485	COG0668	transmembrane transport
LO010_RS07515	COG4773	Receptor
LO010_RS07540	COG0589	response to stress
LO010_RS07565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LO010_RS07575	COG3135	benzoate transporter
LO010_RS07580	COG1522	sequence-specific DNA binding
LO010_RS07590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LO010_RS07595	COG0583	DNA-binding transcription factor activity
LO010_RS07605	COG0183	Belongs to the thiolase family
LO010_RS07615	COG2030	dehydratase
LO010_RS07620	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LO010_RS07645	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LO010_RS07660	COG0824	Thioesterase
LO010_RS07665	COG1454	alcohol dehydrogenase
LO010_RS07675	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LO010_RS07705	COG0069	glutamate synthase activity
LO010_RS07765	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO010_RS08010	COG2814	Major facilitator Superfamily
LO010_RS08025	COG0511	ligase activity, forming carbon-carbon bonds
LO010_RS08045	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO010_RS08045	COG1116	anion transmembrane transporter activity
LO010_RS08050	COG0745	RESPONSE REGULATOR receiver
LO010_RS08060	COG2146	nitrite reductase [NAD(P)H] activity
LO010_RS08060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO010_RS08065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO010_RS08070	COG0243	molybdopterin cofactor binding
LO010_RS08080	COG0243	molybdopterin cofactor binding
LO010_RS08085	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LO010_RS08100	COG0315	cyclic pyranopterin monophosphate synthase activity
LO010_RS08100	COG0521	Mo-molybdopterin cofactor biosynthetic process
LO010_RS08105	COG0303	'Molybdopterin
LO010_RS08115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO010_RS08120	COG0697	spore germination
LO010_RS08140	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LO010_RS08145	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LO010_RS08200	COG2204	response regulator
LO010_RS08205	COG3852	Histidine kinase
LO010_RS08230	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LO010_RS08235	COG0575	Belongs to the CDS family
LO010_RS08250	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO010_RS08270	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LO010_RS08285	COG2137	regulation of response to DNA damage stimulus
LO010_RS08295	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LO010_RS08300	COG1011	Hydrolase
LO010_RS08325	COG1522	sequence-specific DNA binding
LO010_RS08335	COG1113	amino acid transport
LO010_RS08355	COG0659	secondary active sulfate transmembrane transporter activity
LO010_RS08360	COG2135	peptidase activity
LO010_RS08380	COG4372	Transposase
LO010_RS08390	COG3300	MHYT domain
LO010_RS08390	COG5001	Diguanylate cyclase
LO010_RS08410	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LO010_RS08410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LO010_RS08410	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LO010_RS08415	COG1105	Belongs to the carbohydrate kinase PfkB family
LO010_RS08420	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LO010_RS08420	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LO010_RS08450	COG0024	Methionine aminopeptidase
LO010_RS08455	COG0583	DNA-binding transcription factor activity
LO010_RS08465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LO010_RS08470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LO010_RS08475	COG0516	GMP reductase activity
LO010_RS08475	COG0517	IMP dehydrogenase activity
LO010_RS08500	COG0552	protein localization to endoplasmic reticulum
LO010_RS08510	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LO010_RS08520	COG4890	Cyd operon protein YbgT
LO010_RS08525	COG1294	oxidase, subunit
LO010_RS08540	COG1585	Membrane protein implicated in regulation of membrane protease activity
LO010_RS08550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LO010_RS08555	COG4774	siderophore transport
LO010_RS08570	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LO010_RS08575	COG0569	domain protein
LO010_RS08580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LO010_RS08610	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LO010_RS08615	COG0542	response to heat
LO010_RS08640	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO010_RS08640	COG1902	pentaerythritol trinitrate reductase activity
LO010_RS08685	COG2323	membrane
LO010_RS08690	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LO010_RS08700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LO010_RS08705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LO010_RS08710	COG0183	Belongs to the thiolase family
LO010_RS08715	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LO010_RS08720	COG0596	Alpha beta hydrolase
LO010_RS08725	COG2271	Major facilitator Superfamily
LO010_RS08730	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LO010_RS08735	COG3485	protocatechuate 3,4-dioxygenase
LO010_RS08740	COG3485	protocatechuate 3,4-dioxygenase
LO010_RS08745	COG0710	3-dehydroquinate dehydratase activity
LO010_RS08750	COG3420	alginic acid biosynthetic process
LO010_RS08755	COG3659	wide pore channel activity
LO010_RS08760	COG4993	Dehydrogenase
LO010_RS08770	COG2391	methyltransferase activity
LO010_RS08785	COG1414	Transcriptional regulator
LO010_RS08790	COG0583	DNA-binding transcription factor activity
LO010_RS08795	COG1960	acyl-CoA dehydrogenase activity
LO010_RS08820	COG2814	Major facilitator Superfamily
LO010_RS08830	COG0154	amidase activity
LO010_RS08850	COG4638	Rieske (2fe-2S)
LO010_RS08860	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS08870	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO010_RS08880	COG3733	amine oxidase
LO010_RS08890	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS08900	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO010_RS08905	COG0183	Belongs to the thiolase family
LO010_RS08910	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LO010_RS08915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LO010_RS08925	COG4829	muconolactone delta-isomerase
LO010_RS08930	COG4948	Mandelate Racemase Muconate Lactonizing
LO010_RS08935	COG0583	DNA-binding transcription factor activity
LO010_RS08945	COG2186	Transcriptional regulator
LO010_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS08995	COG0789	Transcriptional regulator
LO010_RS09020	COG1309	transcriptional regulator
LO010_RS09025	COG0583	DNA-binding transcription factor activity
LO010_RS09030	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS09040	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS09050	COG1960	acyl-CoA dehydrogenase activity
LO010_RS09060	COG0318	PFAM AMP-dependent synthetase and ligase
LO010_RS09110	COG2188	Transcriptional regulator
LO010_RS09125	COG0583	DNA-binding transcription factor activity
LO010_RS09140	COG1566	PFAM secretion protein HlyD family protein
LO010_RS09155	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS09160	COG0129	dihydroxy-acid dehydratase activity
LO010_RS09170	COG0583	DNA-binding transcription factor activity
LO010_RS09175	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LO010_RS09185	COG2084	Dehydrogenase
LO010_RS09190	COG2207	Transcriptional regulator
LO010_RS09195	COG1064	alcohol dehydrogenase
LO010_RS09205	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO010_RS09210	COG1120	ATPase activity
LO010_RS09230	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LO010_RS09320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LO010_RS09375	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS09390	COG2207	Transcriptional regulator
LO010_RS09400	COG2205	protein histidine kinase activity
LO010_RS09405	COG0745	RESPONSE REGULATOR receiver
LO010_RS09410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO010_RS09415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LO010_RS09565	COG3539	Fimbrial protein
LO010_RS09590	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LO010_RS09600	COG0753	catalase activity
LO010_RS09615	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LO010_RS09675	COG1535	isochorismatase
LO010_RS09675	COG3433	isochorismatase activity
LO010_RS09680	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS09685	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LO010_RS09690	COG4149	molybdate abc transporter
LO010_RS09695	COG0725	ABC transporter, periplasmic molybdate-binding protein
LO010_RS09705	COG4638	Rieske (2fe-2S)
LO010_RS09710	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LO010_RS09715	COG0543	2 iron, 2 sulfur cluster binding
LO010_RS09715	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO010_RS09730	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO010_RS09740	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS09755	COG2207	Transcriptional regulator
LO010_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS09765	COG2610	gluconate transmembrane transporter activity
LO010_RS09775	COG0583	DNA-binding transcription factor activity
LO010_RS09790	COG2031	fatty acid transporter
LO010_RS09795	COG0183	Belongs to the thiolase family
LO010_RS09800	COG0583	DNA-binding transcription factor activity
LO010_RS09805	COG0583	DNA-binding transcription factor activity
LO010_RS09820	COG1027	Aspartate ammonia-lyase
LO010_RS09830	COG0477	Major facilitator Superfamily
LO010_RS09850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO010_RS09855	COG4521	taurine ABC transporter
LO010_RS09870	COG2188	Transcriptional regulator
LO010_RS09880	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LO010_RS09885	COG1733	regulation of RNA biosynthetic process
LO010_RS09890	COG2207	Transcriptional regulator
LO010_RS09890	COG3708	Transcriptional regulator
LO010_RS09905	COG0730	response to heat
LO010_RS09920	COG3453	Protein conserved in bacteria
LO010_RS09920	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO010_RS09930	COG3781	membrane
LO010_RS09935	COG1063	alcohol dehydrogenase
LO010_RS09945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO010_RS09950	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO010_RS09955	COG0022	dehydrogenase e1 component
LO010_RS09960	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LO010_RS09965	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LO010_RS09980	COG3706	GGDEF domain
LO010_RS09995	COG0133	tryptophan synthase activity
LO010_RS10005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LO010_RS10040	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LO010_RS10065	COG2226	methyltransferase
LO010_RS10125	COG0842	Transport permease protein
LO010_RS10130	COG0842	Transport permease protein
LO010_RS10135	COG1131	(ABC) transporter
LO010_RS10150	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LO010_RS10155	COG4773	Receptor
LO010_RS10175	COG0730	response to heat
LO010_RS10180	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LO010_RS10195	COG0406	alpha-ribazole phosphatase activity
LO010_RS10200	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LO010_RS10215	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO010_RS10245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LO010_RS10255	COG4264	IucA IucC family
LO010_RS10260	COG4264	IucA IucC family
LO010_RS10265	COG2814	Major facilitator Superfamily
LO010_RS10280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LO010_RS10295	COG1960	acyl-CoA dehydrogenase activity
LO010_RS10300	COG1960	acyl-CoA dehydrogenase activity
LO010_RS10305	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LO010_RS10310	COG2207	Transcriptional regulator
LO010_RS10315	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LO010_RS10320	COG0776	regulation of translation
LO010_RS10345	COG0822	iron-sulfur transferase activity
LO010_RS10350	COG0316	Belongs to the HesB IscA family
LO010_RS10380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LO010_RS10400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LO010_RS10405	COG0702	epimerase
LO010_RS10440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO010_RS10450	COG0339	signal peptide processing
LO010_RS10460	COG4166	transmembrane transport
LO010_RS10495	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LO010_RS10500	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LO010_RS10530	COG0776	regulation of translation
LO010_RS10595	COG0084	hydrolase, TatD family'
LO010_RS10615	COG1663	tetraacyldisaccharide 4'-kinase activity
LO010_RS10620	COG1132	(ABC) transporter
LO010_RS10630	COG0811	peptide transport
LO010_RS10635	COG1475	DNA binding
LO010_RS10640	COG1192	Involved in chromosome partitioning
LO010_RS10650	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LO010_RS10665	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LO010_RS10670	COG0191	fructose-bisphosphate aldolase activity
LO010_RS10690	COG0424	maF-like protein
LO010_RS10695	COG2850	peptidyl-arginine hydroxylation
LO010_RS10705	COG0640	Transcriptional regulator
LO010_RS10715	COG3619	membrane
LO010_RS10720	COG3122	Protein conserved in bacteria
LO010_RS10725	COG1132	(ABC) transporter
LO010_RS10745	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LO010_RS10750	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LO010_RS10760	COG0506	proline dehydrogenase activity
LO010_RS10760	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LO010_RS10760	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LO010_RS10765	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LO010_RS10780	COG3698	Phosphodiester glycosidase
LO010_RS10795	COG2353	YceI-like domain
LO010_RS10805	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LO010_RS10860	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LO010_RS10860	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LO010_RS10885	COG3539	Fimbrial protein
LO010_RS10890	COG3121	Chaperone
LO010_RS10940	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LO010_RS10950	COG0583	DNA-binding transcription factor activity
LO010_RS10965	COG2826	transposase and inactivated derivatives, IS30 family
LO010_RS10975	COG1309	transcriptional regulator
LO010_RS10990	COG1522	sequence-specific DNA binding
LO010_RS11000	COG1126	abc transporter atp-binding protein
LO010_RS11005	COG0765	amino acid transport
LO010_RS11010	COG0765	amino acid transport
LO010_RS11045	COG1464	Belongs to the NlpA lipoprotein family
LO010_RS11055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LO010_RS11060	COG2011	ABC-type metal ion transport system permease component
LO010_RS11065	COG0012	GTP binding
LO010_RS11090	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LO010_RS11130	COG0386	Belongs to the glutathione peroxidase family
LO010_RS11140	COG0436	Aminotransferase
LO010_RS11145	COG1301	dicarboxylic acid transport
LO010_RS11180	COG3634	alkyl hydroperoxide reductase activity
LO010_RS11195	COG0583	DNA-binding transcription factor activity
LO010_RS11200	COG0798	PFAM Bile acid sodium symporter
LO010_RS11205	COG0640	Transcriptional regulator
LO010_RS11220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LO010_RS11230	COG0583	DNA-binding transcription factor activity
LO010_RS11240	COG1953	Uracil, thiamine, allantoin
LO010_RS11250	COG2175	clavaminate synthase activity
LO010_RS11255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO010_RS11260	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LO010_RS11265	COG4521	taurine ABC transporter
LO010_RS11275	COG0477	Major facilitator Superfamily
LO010_RS11305	COG1271	oxidase subunit
LO010_RS11310	COG1294	oxidase, subunit
LO010_RS11320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO010_RS11340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LO010_RS11360	COG3052	prosthetic group binding
LO010_RS11365	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LO010_RS11375	COG0583	DNA-binding transcription factor activity
LO010_RS11385	COG2814	Major facilitator Superfamily
LO010_RS11400	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO010_RS11405	COG1346	cytolysis
LO010_RS11415	COG0583	DNA-binding transcription factor activity
LO010_RS11420	COG0625	glutathione transferase activity
LO010_RS11425	COG0625	glutathione transferase activity
LO010_RS11430	COG0583	DNA-binding transcription factor activity
LO010_RS11450	COG1045	serine acetyltransferase
LO010_RS11460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO010_RS11465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LO010_RS11470	COG1280	lysine exporter protein (LysE YggA)
LO010_RS11485	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LO010_RS11490	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LO010_RS11495	COG1126	abc transporter atp-binding protein
LO010_RS11500	COG0765	amino acid transport
LO010_RS11505	COG0765	amino acid transport
LO010_RS11525	COG0784	Response regulator, receiver
LO010_RS11525	COG2205	protein histidine kinase activity
LO010_RS11545	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LO010_RS11565	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS11620	COG0583	DNA-binding transcription factor activity
LO010_RS11640	COG0318	PFAM AMP-dependent synthetase and ligase
LO010_RS11645	COG1309	transcriptional regulator
LO010_RS11655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LO010_RS11660	COG1024	Enoyl-CoA hydratase
LO010_RS11665	COG4770	biotin carboxylase activity
LO010_RS11675	COG0583	DNA-binding transcription factor activity
LO010_RS11690	COG1960	acyl-CoA dehydrogenase activity
LO010_RS11700	COG2814	Major facilitator Superfamily
LO010_RS11710	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LO010_RS11715	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LO010_RS11720	COG2814	Major facilitator Superfamily
LO010_RS11725	COG1960	acyl-CoA dehydrogenase activity
LO010_RS11730	COG1024	Enoyl-CoA hydratase
LO010_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS11740	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO010_RS11745	COG0183	Belongs to the thiolase family
LO010_RS11755	COG2814	Major facilitator Superfamily
LO010_RS11765	COG1024	Enoyl-CoA hydratase
LO010_RS11780	COG1960	acyl-CoA dehydrogenase activity
LO010_RS11785	COG2814	Major facilitator Superfamily
LO010_RS11790	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO010_RS11795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LO010_RS11810	COG3842	ATPase activity
LO010_RS11815	COG1840	ABC-type Fe3 transport system, periplasmic component
LO010_RS11825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO010_RS11830	COG1414	Transcriptional regulator
LO010_RS11840	COG0583	DNA-binding transcription factor activity
LO010_RS11845	COG3038	cytochrome b561
LO010_RS11850	COG0753	catalase activity
LO010_RS11855	COG2271	Major facilitator Superfamily
LO010_RS11860	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO010_RS11865	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO010_RS11880	COG2207	Transcriptional regulator
LO010_RS11915	COG2050	protein possibly involved in aromatic compounds catabolism
LO010_RS11925	COG3327	negative regulation of DNA-templated transcription, initiation
LO010_RS11930	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LO010_RS11935	COG0183	Belongs to the thiolase family
LO010_RS11940	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO010_RS11945	COG1024	Enoyl-CoA hydratase
LO010_RS11950	COG1024	Enoyl-CoA hydratase
LO010_RS11955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO010_RS11960	COG2151	metal-sulfur cluster biosynthetic enzyme
LO010_RS11965	COG3396	Phenylacetate-CoA oxygenase
LO010_RS11970	COG3460	Phenylacetate-CoA oxygenase
LO010_RS11975	COG3396	Phenylacetate-CoA oxygenase
LO010_RS11980	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS11980	COG2030	dehydratase
LO010_RS11985	COG1760	l-serine dehydratase
LO010_RS11990	COG0531	amino acid
LO010_RS11995	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS12020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LO010_RS12040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO010_RS12050	COG0789	Transcriptional regulator
LO010_RS12060	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LO010_RS12170	COG0038	chloride channel
LO010_RS12175	COG4770	biotin carboxylase activity
LO010_RS12195	COG1914	H( )-stimulated, divalent metal cation uptake system
LO010_RS12200	COG0583	DNA-binding transcription factor activity
LO010_RS12235	COG4372	Transposase
LO010_RS12245	COG2963	transposase activity
LO010_RS12270	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO010_RS12295	COG4521	taurine ABC transporter
LO010_RS12300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO010_RS12305	COG1116	anion transmembrane transporter activity
LO010_RS12310	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LO010_RS12320	COG2814	Major facilitator Superfamily
LO010_RS12335	COG1560	Kdo2-lipid A biosynthetic process
LO010_RS12350	COG1522	sequence-specific DNA binding
LO010_RS12365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LO010_RS12375	COG4122	O-methyltransferase activity
LO010_RS12410	COG1137	ATPase activity
LO010_RS12415	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LO010_RS12425	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LO010_RS12430	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LO010_RS12430	COG0517	IMP dehydrogenase activity
LO010_RS12480	COG2814	Major facilitator Superfamily
LO010_RS12520	COG1278	Cold shock
LO010_RS12525	COG1280	lysine exporter protein (LysE YggA)
LO010_RS12555	COG1570	exodeoxyribonuclease VII activity
LO010_RS12640	COG2871	sodium ion transport
LO010_RS12650	COG0583	DNA-binding transcription factor activity
LO010_RS12670	COG0633	Ferredoxin
LO010_RS12670	COG0543	2 iron, 2 sulfur cluster binding
LO010_RS12675	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS12680	COG3135	benzoate transporter
LO010_RS12685	COG2814	Major facilitator Superfamily
LO010_RS12700	COG1643	Atp-dependent helicase
LO010_RS12705	COG0450	alkyl hydroperoxide reductase
LO010_RS12715	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO010_RS12725	COG3634	alkyl hydroperoxide reductase activity
LO010_RS12750	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LO010_RS12755	COG0625	glutathione transferase activity
LO010_RS12765	COG2885	chlorophyll binding
LO010_RS12800	COG0542	response to heat
LO010_RS12815	COG1765	OsmC-like protein
LO010_RS12830	COG0667	Aldo Keto reductase
LO010_RS12845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LO010_RS12860	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LO010_RS12870	COG0582	viral genome integration into host DNA
LO010_RS12900	COG3293	Transposase
LO010_RS12905	COG1063	alcohol dehydrogenase
LO010_RS13125	COG5410	chromosome segregation
LO010_RS13340	COG0527	aspartate kinase activity
LO010_RS13350	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LO010_RS13360	COG3038	cytochrome b561
LO010_RS13365	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LO010_RS13380	COG2072	flavoprotein involved in K transport
LO010_RS13395	COG1741	Belongs to the pirin family
LO010_RS13400	COG1309	transcriptional regulator
LO010_RS13410	COG0300	oxidoreductase activity
LO010_RS13415	COG2072	flavoprotein involved in K transport
LO010_RS13420	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LO010_RS13465	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LO010_RS13480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO010_RS13495	COG2814	Major facilitator Superfamily
LO010_RS13500	COG1024	Enoyl-CoA hydratase
LO010_RS13505	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS13515	COG1960	acyl-CoA dehydrogenase activity
LO010_RS13540	COG2186	Transcriptional regulator
LO010_RS13545	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS13555	COG4948	Mandelate Racemase Muconate Lactonizing
LO010_RS13560	COG2271	Major facilitator Superfamily
LO010_RS13565	COG2721	sulfolactate sulfo-lyase activity
LO010_RS13570	COG0697	spore germination
LO010_RS13605	COG1113	amino acid transport
LO010_RS13625	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS13645	COG0531	amino acid
LO010_RS13655	COG1113	amino acid transport
LO010_RS13685	COG3209	COG3209 Rhs family protein
LO010_RS13715	COG4269	membrane
LO010_RS13730	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO010_RS13730	COG1902	pentaerythritol trinitrate reductase activity
LO010_RS13740	COG2203	Gaf domain
LO010_RS13740	COG3706	GGDEF domain
LO010_RS13740	COG4251	negative regulation of phosphorylation
LO010_RS13740	COG5001	Diguanylate cyclase
LO010_RS13750	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO010_RS13770	COG4172	Belongs to the ABC transporter superfamily
LO010_RS13775	COG4239	(ABC) transporter, permease
LO010_RS13780	COG4174	ABC transporter (Permease)
LO010_RS13790	COG0741	lytic transglycosylase activity
LO010_RS13790	COG0741	lytic transglycosylase activity
LO010_RS13790	COG1388	LysM domain
LO010_RS13790	COG1388	LysM domain
LO010_RS13795	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO010_RS13835	COG0583	DNA-binding transcription factor activity
LO010_RS13840	COG1279	arginine transmembrane transporter activity
LO010_RS13860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO010_RS13865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO010_RS13870	COG0006	proline dipeptidase activity
LO010_RS13965	COG0739	heme binding
LO010_RS13980	COG1598	PFAM Uncharacterised protein family UPF0150
LO010_RS14040	COG0515	serine threonine protein kinase
LO010_RS14040	COG2815	serine threonine protein kinase
LO010_RS14105	COG5410	chromosome segregation
LO010_RS14225	COG3620	sequence-specific DNA binding
LO010_RS14305	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LO010_RS14325	COG3384	dioxygenase
LO010_RS14335	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LO010_RS14340	COG2878	Part of a membrane complex involved in electron transport
LO010_RS14345	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LO010_RS14370	COG0768	penicillin binding
LO010_RS14375	COG0742	ribosomal rna small subunit methyltransferase
LO010_RS14390	COG0830	nickel cation binding
LO010_RS14400	COG0804	urea catabolic process
LO010_RS14440	COG1253	flavin adenine dinucleotide binding
LO010_RS14445	COG2851	Citrate transporter
LO010_RS14495	COG1773	rubredoxin
LO010_RS14500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO010_RS14510	COG0583	DNA-binding transcription factor activity
LO010_RS14540	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LO010_RS14545	COG4181	ATPase activity
LO010_RS14590	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LO010_RS14610	COG0306	phosphate transporter
LO010_RS14620	COG3958	Transketolase
LO010_RS14625	COG3959	Transketolase, thiamine diphosphate binding domain
LO010_RS14630	COG2271	Major facilitator Superfamily
LO010_RS14635	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS14640	COG0583	DNA-binding transcription factor activity
LO010_RS14655	COG2223	nitrite transmembrane transporter activity
LO010_RS14660	COG2207	Transcriptional regulator
LO010_RS14665	COG2066	Belongs to the glutaminase family
LO010_RS14670	COG0242	peptide deformylase activity
LO010_RS14675	COG0477	Major facilitator Superfamily
LO010_RS14685	COG0028	Belongs to the TPP enzyme family
LO010_RS14690	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS14700	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS14705	COG2267	carboxylic ester hydrolase activity
LO010_RS14715	COG2271	Major facilitator Superfamily
LO010_RS14740	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS14760	COG1414	Transcriptional regulator
LO010_RS14775	COG1024	Enoyl-CoA hydratase
LO010_RS14785	COG1215	transferase activity, transferring glycosyl groups
LO010_RS14790	COG0726	polysaccharide deacetylase
LO010_RS14790	COG1649	PFAM Uncharacterised BCR, COG1649
LO010_RS14800	COG4681	YaeQ
LO010_RS14810	COG0523	cobalamin synthesis protein
LO010_RS14820	COG1607	acyl-coa hydrolase
LO010_RS14830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LO010_RS14835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LO010_RS14840	COG1309	transcriptional regulator
LO010_RS14865	COG2040	homocysteine
LO010_RS14870	COG0531	amino acid
LO010_RS14895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO010_RS14900	COG0477	Major facilitator Superfamily
LO010_RS14910	COG4372	Transposase
LO010_RS14920	COG2963	transposase activity
LO010_RS14965	COG0405	Gamma-glutamyltransferase
LO010_RS14970	COG2814	Major facilitator Superfamily
LO010_RS14980	COG2050	protein possibly involved in aromatic compounds catabolism
LO010_RS14995	COG1090	epimerase
LO010_RS15015	COG0420	3'-5' exonuclease activity
LO010_RS15040	COG0735	belongs to the Fur family
LO010_RS15045	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO010_RS15065	COG0121	glutamine amidotransferase
LO010_RS15080	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LO010_RS15090	COG0210	DNA helicase
LO010_RS15095	COG2885	chlorophyll binding
LO010_RS15100	COG0204	Acyl-transferase
LO010_RS15115	COG2894	cell division
LO010_RS15130	COG1280	lysine exporter protein (LysE YggA)
LO010_RS15135	COG1674	ftsk spoiiie
LO010_RS15135	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LO010_RS15140	COG0492	ferredoxin-NADP+ reductase activity
LO010_RS15145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LO010_RS15155	COG0456	acetyltransferase
LO010_RS15200	COG1981	membrane
LO010_RS15215	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LO010_RS15215	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LO010_RS15235	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS15245	COG0657	acetylesterase activity
LO010_RS15255	COG0473	3-isopropylmalate dehydrogenase activity
LO010_RS15260	COG0583	DNA-binding transcription factor activity
LO010_RS15280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO010_RS15305	COG0564	pseudouridine synthase activity
LO010_RS15315	COG0358	DNA primase activity
LO010_RS15330	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LO010_RS15360	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LO010_RS15390	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LO010_RS15400	COG0352	thiamine-phosphate diphosphorylase activity
LO010_RS15400	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LO010_RS15400	COG0351	phosphomethylpyrimidine kinase
LO010_RS15405	COG1652	LysM domain
LO010_RS15430	COG1399	metal-binding, possibly nucleic acid-binding protein
LO010_RS15435	COG3101	peptidyl-lysine hydroxylation
LO010_RS15440	COG0009	L-threonylcarbamoyladenylate synthase
LO010_RS15445	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LO010_RS15450	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LO010_RS15465	COG4106	trans-aconitate 2-methyltransferase activity
LO010_RS15480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO010_RS15480	COG2226	methyltransferase
LO010_RS15480	COG0596	Alpha beta hydrolase
LO010_RS15485	COG1877	trehalose-phosphatase activity
LO010_RS15490	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LO010_RS15495	COG2223	nitrite transmembrane transporter activity
LO010_RS15515	COG1196	nuclear chromosome segregation
LO010_RS15525	COG0730	response to heat
LO010_RS15540	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LO010_RS15550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LO010_RS15600	COG0489	protein tyrosine kinase activity
LO010_RS15610	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO010_RS15610	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO010_RS15640	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LO010_RS15645	COG2081	HI0933 family
LO010_RS15655	COG0668	transmembrane transport
LO010_RS15675	COG0583	DNA-binding transcription factor activity
LO010_RS15700	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO010_RS15705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LO010_RS15735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LO010_RS15785	COG0745	RESPONSE REGULATOR receiver
LO010_RS15805	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LO010_RS15835	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO010_RS15850	COG0583	DNA-binding transcription factor activity
LO010_RS15880	COG0583	DNA-binding transcription factor activity
LO010_RS15895	COG0583	DNA-binding transcription factor activity
LO010_RS15900	COG1053	succinate dehydrogenase
LO010_RS15910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO010_RS15915	COG2814	Major facilitator Superfamily
LO010_RS15920	COG1960	acyl-CoA dehydrogenase activity
LO010_RS15925	COG0583	DNA-binding transcription factor activity
LO010_RS15930	COG1063	alcohol dehydrogenase
LO010_RS15960	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LO010_RS15965	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LO010_RS15970	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LO010_RS15985	COG3667	copper resistance
LO010_RS15990	COG2132	Multicopper oxidase
LO010_RS16000	COG0561	phosphatase activity
LO010_RS16005	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LO010_RS16015	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LO010_RS16030	COG1214	PFAM Peptidase M22, glycoprotease
LO010_RS16080	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LO010_RS16090	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LO010_RS16095	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LO010_RS16100	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LO010_RS16160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LO010_RS16170	COG1846	Transcriptional regulator
LO010_RS16175	COG1764	response to oxidative stress
LO010_RS16215	COG0037	tRNA processing
LO010_RS16225	COG0248	Ppx GppA phosphatase
LO010_RS16255	COG0072	phenylalanine-tRNA ligase activity
LO010_RS16300	COG1238	metal cluster binding
LO010_RS16305	COG0625	glutathione transferase activity
LO010_RS16320	COG0318	PFAM AMP-dependent synthetase and ligase
LO010_RS16325	COG3028	Belongs to the UPF0307 family
LO010_RS16330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LO010_RS16350	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LO010_RS16355	COG0617	tRNA 3'-terminal CCA addition
LO010_RS16360	COG1555	photosystem II stabilization
LO010_RS16365	COG3956	TIGRFAM MazG family protein
LO010_RS16375	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LO010_RS16395	COG0784	Response regulator, receiver
LO010_RS16395	COG2205	protein histidine kinase activity
LO010_RS16395	COG5002	protein histidine kinase activity
LO010_RS16400	COG1024	Enoyl-CoA hydratase
LO010_RS16405	COG2084	Dehydrogenase
LO010_RS16410	COG3622	Belongs to the hyi family
LO010_RS16440	COG0697	spore germination
LO010_RS16450	COG2814	Major facilitator Superfamily
LO010_RS16455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LO010_RS16465	COG0583	DNA-binding transcription factor activity
LO010_RS16475	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LO010_RS16485	COG0084	hydrolase, TatD family'
LO010_RS16500	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LO010_RS16530	COG0440	acetolactate synthase activity
LO010_RS16535	COG0028	Belongs to the TPP enzyme family
LO010_RS16560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO010_RS16565	COG1136	(ABC) transporter
LO010_RS16565	COG0577	efflux transmembrane transporter activity
LO010_RS16570	COG1538	Outer membrane efflux protein
LO010_RS16585	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LO010_RS16590	COG1162	GTPase activity
LO010_RS16600	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LO010_RS16640	COG1426	Protein conserved in bacteria
LO010_RS16675	COG0793	Belongs to the peptidase S41A family
LO010_RS16690	COG2267	carboxylic ester hydrolase activity
LO010_RS16700	COG1012	belongs to the aldehyde dehydrogenase family
LO010_RS16705	COG3265	gluconokinase activity
LO010_RS16715	COG0800	Aldolase
LO010_RS16725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LO010_RS16730	COG0857	belongs to the CobB CobQ family
LO010_RS16730	COG0280	phosphate acetyltransferase
LO010_RS16735	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LO010_RS16735	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LO010_RS16755	COG0740	serine-type endopeptidase activity
LO010_RS16765	COG4774	siderophore transport
LO010_RS16775	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO010_RS16785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO010_RS16785	COG2813	Specifically methylates the guanine in position
LO010_RS16885	COG0788	formyltetrahydrofolate deformylase activity
LO010_RS16910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LO010_RS16910	COG4651	solute:proton antiporter activity
LO010_RS16930	COG0724	RNA recognition motif
LO010_RS16935	COG0210	DNA helicase
LO010_RS16960	COG1733	regulation of RNA biosynthetic process
LO010_RS16970	COG2900	Belongs to the SlyX family
LO010_RS16975	COG0488	(ABC) transporter
LO010_RS16980	COG1280	lysine exporter protein (LysE YggA)
LO010_RS16985	COG1560	Kdo2-lipid A biosynthetic process
LO010_RS16995	COG1301	dicarboxylic acid transport
LO010_RS17050	COG0473	3-isopropylmalate dehydrogenase activity
LO010_RS17075	COG0583	DNA-binding transcription factor activity
LO010_RS17125	COG0583	DNA-binding transcription factor activity
LO010_RS17135	COG0625	glutathione transferase activity
LO010_RS17140	COG2378	regulation of single-species biofilm formation
LO010_RS17145	COG0546	phosphoglycolate phosphatase activity
LO010_RS17155	COG1530	ribonuclease E activity
LO010_RS17160	COG0318	PFAM AMP-dependent synthetase and ligase
LO010_RS17175	COG0583	DNA-binding transcription factor activity
LO010_RS17180	COG4221	oxidoreductase activity
LO010_RS17185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LO010_RS17195	COG0534	Mate efflux family protein
LO010_RS17210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LO010_RS17235	COG0493	'glutamate synthase
LO010_RS17235	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO010_RS17245	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LO010_RS17250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO010_RS17265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LO010_RS17275	COG0644	oxidoreductase
LO010_RS17275	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LO010_RS17285	COG0425	Belongs to the sulfur carrier protein TusA family
LO010_RS17290	COG4535	Mg2 and Co2 transporter CorC
LO010_RS17300	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO010_RS17320	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LO010_RS17325	COG0475	glutathione-regulated potassium exporter activity
LO010_RS17325	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LO010_RS17340	COG0484	heat shock protein binding
LO010_RS17345	COG0789	Transcriptional regulator
LO010_RS17350	COG0598	Magnesium transport protein CorA
LO010_RS17365	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LO010_RS17370	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LO010_RS17375	COG1074	ATP-dependent DNA helicase activity
LO010_RS17380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LO010_RS17400	COG2226	methyltransferase
LO010_RS17415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO010_RS17420	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LO010_RS17435	COG2111	Na H antiporter
LO010_RS17435	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LO010_RS17440	COG1006	Multisubunit Na H antiporter MnhC subunit
LO010_RS17445	COG0651	ATP synthesis coupled electron transport
LO010_RS17450	COG1863	multisubunit Na H antiporter MnhE subunit
LO010_RS17455	COG2212	antiporter activity
LO010_RS17460	COG1320	monovalent cation:proton antiporter activity
LO010_RS17475	COG0195	Participates in both transcription termination and antitermination
LO010_RS17525	COG0237	dephospho-CoA kinase activity
LO010_RS17535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LO010_RS17550	COG0497	DNA recombination
LO010_RS17560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LO010_RS17590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LO010_RS17590	COG2169	Transcriptional regulator
LO010_RS17600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LO010_RS17660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LO010_RS17675	COG0326	Molecular chaperone. Has ATPase activity
LO010_RS17690	COG2056	Na+-H+ antiporter family
LO010_RS17695	COG0596	Alpha beta hydrolase
LO010_RS17715	COG4372	Transposase
LO010_RS17725	COG2963	transposase activity
LO010_RS17805	COG0546	phosphoglycolate phosphatase activity
LO010_RS17810	COG1716	ATPase activity
LO010_RS17855	COG0181	hydroxymethylbilane synthase activity
LO010_RS17865	COG3275	phosphorelay sensor kinase activity
LO010_RS17885	COG1538	Outer membrane efflux protein
LO010_RS17890	COG0697	spore germination
LO010_RS17915	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LO010_RS17920	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LO010_RS17925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LO010_RS17930	COG0772	Belongs to the SEDS family
LO010_RS17955	COG4974	Belongs to the 'phage' integrase family
LO010_RS17960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO010_RS17970	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LO010_RS17980	COG2197	response regulator
LO010_RS17995	COG0793	Belongs to the peptidase S41A family
LO010_RS18000	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LO010_RS18005	COG0795	lipopolysaccharide-transporting ATPase activity
LO010_RS18045	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LO010_RS18045	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LO010_RS18055	COG0004	ammonium transporteR
LO010_RS18060	COG0347	Belongs to the P(II) protein family
LO010_RS18080	COG2826	transposase and inactivated derivatives, IS30 family
LO010_RS18150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO010_RS18155	COG1230	cation diffusion facilitator family transporter
LO010_RS18165	COG0640	Transcriptional regulator
LO010_RS18175	COG0789	Transcriptional regulator
LO010_RS18205	COG2814	Major facilitator Superfamily
LO010_RS18245	COG0633	Ferredoxin
LO010_RS18315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO010_RS18335	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LO010_RS18350	COG0318	PFAM AMP-dependent synthetase and ligase
LO010_RS18360	COG0477	Major facilitator Superfamily
LO010_RS18365	COG2860	membrane
LO010_RS18375	COG1253	flavin adenine dinucleotide binding
LO010_RS18385	COG0477	Major facilitator Superfamily
LO010_RS18395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LO010_RS18435	COG0655	NAD(P)H dehydrogenase (quinone) activity
LO010_RS18445	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LO010_RS18475	COG1309	transcriptional regulator
LO010_RS18510	COG0758	DNA mediated transformation
LO010_RS18520	COG0697	spore germination
LO010_RS18525	COG1309	transcriptional regulator
LO010_RS18540	COG0386	Belongs to the glutathione peroxidase family
LO010_RS18605	COG1121	(ABC) transporter
LO010_RS18610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LO010_RS18615	COG1280	lysine exporter protein (LysE YggA)
LO010_RS18620	COG2837	iron assimilation
LO010_RS18655	COG3293	Transposase
LO010_RS18685	COG0519	Catalyzes the synthesis of GMP from XMP
LO010_RS18685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LO010_RS18690	COG4399	Belongs to the UPF0754 family
LO010_RS18695	COG2259	Doxx family
LO010_RS18700	COG0586	Pfam SNARE associated Golgi protein
LO010_RS18715	COG1192	Involved in chromosome partitioning
LO010_RS18725	COG0271	Belongs to the BolA IbaG family
LO010_RS18760	COG3756	Protein conserved in bacteria
LO010_RS18770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO010_RS18785	COG0753	catalase activity
LO010_RS18790	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO010_RS18825	COG3550	peptidyl-serine autophosphorylation
LO010_RS18830	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LO010_RS18855	COG4628	conserved protein (DUF2132)
LO010_RS18890	COG0564	pseudouridine synthase activity
LO010_RS18920	COG1051	belongs to the nudix hydrolase family
LO010_RS18940	COG1403	HNH endonuclease
LO010_RS18945	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LO010_RS18960	COG1802	Transcriptional regulator
LO010_RS18970	COG1448	Aminotransferase
LO010_RS18975	COG0277	FAD linked oxidase domain protein
LO010_RS18985	COG2186	Transcriptional regulator
LO010_RS18995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LO010_RS19005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LO010_RS19020	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LO010_RS19025	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LO010_RS19030	COG1216	Glycosyl transferase, family 2
LO010_RS19050	COG2244	polysaccharide biosynthetic process
LO010_RS19055	COG2089	acid synthase
LO010_RS19070	COG1083	cytidylyl-transferase
LO010_RS19075	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LO010_RS19080	COG1086	Polysaccharide biosynthesis protein
LO010_RS19085	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LO010_RS19115	COG0728	peptidoglycan biosynthetic process
LO010_RS19120	COG3023	N-Acetylmuramoyl-L-alanine amidase
LO010_RS19180	COG0546	phosphoglycolate phosphatase activity
LO010_RS19185	COG1028	Short-chain dehydrogenase reductase Sdr
LO010_RS19205	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO010_RS19210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO010_RS19215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO010_RS19220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO010_RS19225	COG1116	anion transmembrane transporter activity
LO010_RS19230	COG1309	transcriptional regulator
LO010_RS19235	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LO010_RS19245	COG0196	riboflavin kinase activity
LO010_RS19250	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LO010_RS19260	COG1047	Peptidyl-prolyl cis-trans
LO010_RS19300	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LO010_RS19305	COG0657	acetylesterase activity
LO010_RS19325	COG0583	DNA-binding transcription factor activity
LO010_RS19355	COG2951	lytic endotransglycosylase activity
LO010_RS19360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LO010_RS19375	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LO010_RS19385	COG0671	phosphoesterase, PA-phosphatase related
LO010_RS19390	COG0861	Integral membrane protein TerC family
LO010_RS19405	COG0754	glutathionylspermidine amidase activity
LO010_RS19415	COG0402	S-adenosylhomocysteine deaminase activity
LO010_RS19430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO010_RS19435	COG1230	cation diffusion facilitator family transporter
LO010_RS19450	COG0706	membrane insertase activity
LO010_RS19510	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LO010_RS19560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LO010_RS19560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LO010_RS19615	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LO010_RS19615	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LO010_RS19620	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LO010_RS19675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO010_RS19860	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LO010_RS19880	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LO010_RS20060	COG0358	DNA primase activity
LO010_RS20120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LO010_RS20125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LO010_RS20135	COG0542	response to heat
LO010_RS20150	COG0747	negative chemotaxis
LO010_RS20160	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO010_RS20165	COG0601	transmembrane transport
LO010_RS20170	COG2963	transposase activity
LO010_RS20215	COG4372	Transposase
LO010_RS20225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO010_RS20230	COG1335	isochorismatase
LO010_RS20320	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LO010_RS20360	COG0582	viral genome integration into host DNA
LO010_RS20365	COG2369	cell adhesion
LO010_RS20420	COG0583	DNA-binding transcription factor activity
LO010_RS20510	COG4993	Dehydrogenase
LO010_RS20625	COG1192	Involved in chromosome partitioning
LO010_RS20655	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
LO010_RS20715	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LO010_RS20770	COG3706	GGDEF domain