locus-tag	class	description
KU053_RS00010	COG0592	DNA-directed DNA polymerase activity
KU053_RS00020	COG0187	DNA topoisomerase II activity
KU053_RS00030	COG0586	Pfam SNARE associated Golgi protein
KU053_RS00035	COG0488	(ABC) transporter
KU053_RS00060	COG0596	Alpha beta hydrolase
KU053_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KU053_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KU053_RS00110	COG0733	neurotransmitter:sodium symporter activity
KU053_RS00150	COG2233	PERMEase
KU053_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU053_RS00200	COG2814	Major facilitator Superfamily
KU053_RS00205	COG0656	L-ascorbic acid biosynthetic process
KU053_RS00210	COG0583	DNA-binding transcription factor activity
KU053_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU053_RS00230	COG1064	alcohol dehydrogenase
KU053_RS00235	COG2818	Glycosylase
KU053_RS00250	COG1194	a g-specific adenine glycosylase
KU053_RS00270	COG2983	Belongs to the UPF0260 family
KU053_RS00275	COG2133	pyrroloquinoline quinone binding
KU053_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KU053_RS00285	COG2116	formate transmembrane transporter activity
KU053_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU053_RS00310	COG1335	isochorismatase
KU053_RS00315	COG0385	Bile acid
KU053_RS00320	COG0534	Mate efflux family protein
KU053_RS00325	COG1683	Conserved Protein
KU053_RS00345	COG0625	glutathione transferase activity
KU053_RS00355	COG1113	amino acid transport
KU053_RS00365	COG0523	cobalamin synthesis protein
KU053_RS00375	COG2188	Transcriptional regulator
KU053_RS00405	COG0010	Belongs to the arginase family
KU053_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU053_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU053_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KU053_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KU053_RS00540	COG0534	Mate efflux family protein
KU053_RS00545	COG0436	Aminotransferase
KU053_RS00550	COG2733	membrane
KU053_RS00565	COG2918	glutathione biosynthetic process
KU053_RS00580	COG1388	LysM domain
KU053_RS00580	COG0791	NLP P60 protein
KU053_RS00595	COG3150	esterase
KU053_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KU053_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU053_RS00630	COG2233	PERMEase
KU053_RS00635	COG2351	hydroxyisourate hydrolase activity
KU053_RS00670	COG3706	GGDEF domain
KU053_RS00685	COG1393	Belongs to the ArsC family
KU053_RS00690	COG0708	Exodeoxyribonuclease III
KU053_RS00710	COG0189	ligase activity
KU053_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KU053_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KU053_RS00755	COG4942	peptidase
KU053_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU053_RS00775	COG2119	membrane
KU053_RS00785	COG2433	Pfam Transposase IS66
KU053_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU053_RS00805	COG0426	domain, Protein
KU053_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KU053_RS00850	COG1902	pentaerythritol trinitrate reductase activity
KU053_RS00855	COG1519	Transferase
KU053_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU053_RS00865	COG0668	transmembrane transport
KU053_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU053_RS00880	COG1335	isochorismatase
KU053_RS00885	COG1522	sequence-specific DNA binding
KU053_RS00890	COG3328	transposase activity
KU053_RS00915	COG0784	Response regulator, receiver
KU053_RS00915	COG2198	Histidine kinase
KU053_RS00915	COG2205	protein histidine kinase activity
KU053_RS00920	COG3162	membrane
KU053_RS00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU053_RS00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU053_RS00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KU053_RS00960	COG1309	transcriptional regulator
KU053_RS00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU053_RS00980	COG0352	thiamine-phosphate diphosphorylase activity
KU053_RS00980	COG0351	phosphomethylpyrimidine kinase
KU053_RS00990	COG2814	Major facilitator Superfamily
KU053_RS01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU053_RS01015	COG1113	amino acid transport
KU053_RS01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU053_RS01030	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS01040	COG1335	isochorismatase
KU053_RS01055	COG1061	Type III restriction enzyme res subunit
KU053_RS01065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU053_RS01070	COG1192	Involved in chromosome partitioning
KU053_RS01080	COG1061	Type III restriction enzyme res subunit
KU053_RS01120	COG2814	Major facilitator Superfamily
KU053_RS01125	COG0583	DNA-binding transcription factor activity
KU053_RS01145	COG0667	Aldo Keto reductase
KU053_RS01180	COG1733	regulation of RNA biosynthetic process
KU053_RS01185	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU053_RS01250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KU053_RS01265	COG2329	Antibiotic biosynthesis monooxygenase
KU053_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KU053_RS01325	COG0427	acetyl-CoA hydrolase
KU053_RS01350	COG0659	secondary active sulfate transmembrane transporter activity
KU053_RS01355	COG4221	oxidoreductase activity
KU053_RS01360	COG2873	o-acetylhomoserine
KU053_RS01365	COG0488	(ABC) transporter
KU053_RS01450	COG0833	amino acid
KU053_RS01495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KU053_RS01500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KU053_RS01515	COG2226	methyltransferase
KU053_RS01565	COG0070	glutamate synthase
KU053_RS01565	COG0069	glutamate synthase activity
KU053_RS01565	COG0067	glutamate synthase
KU053_RS01570	COG0493	'glutamate synthase
KU053_RS01580	COG1704	LemA family
KU053_RS01585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KU053_RS01605	COG3307	-O-antigen
KU053_RS01625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU053_RS01640	COG0194	GDP metabolic process
KU053_RS01690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KU053_RS01710	COG5380	lipid catabolic process
KU053_RS01715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KU053_RS01740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU053_RS01745	COG0277	FAD linked oxidase domain protein
KU053_RS01755	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KU053_RS01760	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU053_RS01775	COG1289	transmembrane transporter activity
KU053_RS01785	COG0628	permease
KU053_RS01790	COG1192	Involved in chromosome partitioning
KU053_RS01820	COG0833	amino acid
KU053_RS01825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU053_RS01830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU053_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS01880	COG0583	DNA-binding transcription factor activity
KU053_RS01925	COG0517	IMP dehydrogenase activity
KU053_RS01930	COG1983	PspC domain protein
KU053_RS01940	COG1960	acyl-CoA dehydrogenase activity
KU053_RS01955	COG0408	coproporphyrinogen oxidase activity
KU053_RS01975	COG0513	Belongs to the DEAD box helicase family
KU053_RS01985	COG1127	ABC transporter
KU053_RS01990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KU053_RS02000	COG2854	intermembrane phospholipid transfer
KU053_RS02010	COG0598	Magnesium transport protein CorA
KU053_RS02020	COG0494	nUDIX hydrolase
KU053_RS02025	COG1040	competence protein
KU053_RS02030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KU053_RS02050	COG1946	Acyl-CoA thioesterase
KU053_RS02055	COG1301	dicarboxylic acid transport
KU053_RS02070	COG1959	2 iron, 2 sulfur cluster binding
KU053_RS02075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU053_RS02075	COG1017	nitric oxide dioxygenase activity
KU053_RS02080	COG0433	COG0433 Predicted ATPase
KU053_RS02085	COG0626	cystathionine gamma-synthase activity
KU053_RS02240	COG1960	acyl-CoA dehydrogenase activity
KU053_RS02245	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KU053_RS02275	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KU053_RS02280	COG0339	signal peptide processing
KU053_RS02285	COG0557	exoribonuclease II activity
KU053_RS02330	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU053_RS02335	COG2169	Transcriptional regulator
KU053_RS02340	COG0697	spore germination
KU053_RS02345	COG1295	ribonuclease BN
KU053_RS02380	COG1702	phosphate starvation-inducible protein PhoH
KU053_RS02390	COG0739	heme binding
KU053_RS02390	COG0741	lytic transglycosylase activity
KU053_RS02390	COG1196	nuclear chromosome segregation
KU053_RS02420	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KU053_RS02425	COG1183	phosphatidylcholine synthase activity
KU053_RS02470	COG1960	acyl-CoA dehydrogenase activity
KU053_RS02475	COG1309	transcriptional regulator
KU053_RS02490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU053_RS02495	COG1960	acyl-CoA dehydrogenase activity
KU053_RS02515	COG2969	positive regulation of protein catabolic process
KU053_RS02525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KU053_RS02540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KU053_RS02545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KU053_RS02565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KU053_RS02575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU053_RS02580	COG1408	metallophosphoesterase
KU053_RS02590	COG2199	diguanylate cyclase activity
KU053_RS02650	COG1607	acyl-coa hydrolase
KU053_RS02680	COG2350	Protein conserved in bacteria
KU053_RS02690	COG0613	PHP domain protein
KU053_RS02695	COG3781	membrane
KU053_RS02705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KU053_RS02710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU053_RS02720	COG1862	Preprotein translocase
KU053_RS02770	COG2205	protein histidine kinase activity
KU053_RS02775	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KU053_RS02795	COG0726	polysaccharide deacetylase
KU053_RS02800	COG0463	Glycosyl transferase, family 2
KU053_RS02805	COG0438	transferase activity, transferring glycosyl groups
KU053_RS02880	COG0625	glutathione transferase activity
KU053_RS02885	COG0583	DNA-binding transcription factor activity
KU053_RS02890	COG1960	acyl-CoA dehydrogenase activity
KU053_RS02895	COG1960	acyl-CoA dehydrogenase activity
KU053_RS02905	COG2205	protein histidine kinase activity
KU053_RS02910	COG0745	RESPONSE REGULATOR receiver
KU053_RS02915	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KU053_RS02935	COG2096	Adenosyltransferase
KU053_RS02985	COG0285	dihydrofolate synthase activity
KU053_RS03005	COG0450	alkyl hydroperoxide reductase
KU053_RS03020	COG0477	Major facilitator Superfamily
KU053_RS03025	COG1272	protein, Hemolysin III
KU053_RS03055	COG0183	Belongs to the thiolase family
KU053_RS03060	COG2207	Transcriptional regulator
KU053_RS03080	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU053_RS03100	COG0183	Belongs to the thiolase family
KU053_RS03110	COG2885	chlorophyll binding
KU053_RS03110	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KU053_RS03120	COG1690	Belongs to the RtcB family
KU053_RS03125	COG0833	amino acid
KU053_RS03135	COG2233	PERMEase
KU053_RS03140	COG1217	gtp-binding protein TYPA
KU053_RS03165	COG2094	Belongs to the DNA glycosylase MPG family
KU053_RS03185	COG1902	pentaerythritol trinitrate reductase activity
KU053_RS03200	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU053_RS03205	COG0354	folic acid binding
KU053_RS03215	COG3189	MarR family transcriptional regulator
KU053_RS03220	COG2824	Alkylphosphonate utilization operon protein PhnA
KU053_RS03225	COG3422	double-strand break repair
KU053_RS03265	COG0840	transmembrane signaling receptor activity
KU053_RS03285	COG5510	response to toxic substance
KU053_RS03295	COG2832	Protein of unknown function (DUF454)
KU053_RS03300	COG1376	ErfK ybiS ycfS ynhG family protein
KU053_RS03340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KU053_RS03350	COG1289	transmembrane transporter activity
KU053_RS03355	COG2814	Major facilitator Superfamily
KU053_RS03375	COG1115	amino acid carrier protein
KU053_RS03380	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU053_RS03385	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU053_RS03390	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KU053_RS03420	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU053_RS03430	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU053_RS03435	COG1077	Cell shape determining protein MreB Mrl
KU053_RS03440	COG1792	Involved in formation and maintenance of cell shape
KU053_RS03445	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KU053_RS03450	COG0424	maF-like protein
KU053_RS03455	COG1530	ribonuclease E activity
KU053_RS03465	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU053_RS03475	COG0560	Phosphoserine phosphatase
KU053_RS03485	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU053_RS03510	COG2207	Transcriptional regulator
KU053_RS03530	COG1113	amino acid transport
KU053_RS03535	COG2828	Protein conserved in bacteria
KU053_RS03540	COG0142	geranyltranstransferase activity
KU053_RS03545	COG2315	Protein conserved in bacteria
KU053_RS03560	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU053_RS03890	COG2194	sulfuric ester hydrolase activity
KU053_RS03895	COG0745	RESPONSE REGULATOR receiver
KU053_RS03900	COG0642	Histidine kinase
KU053_RS03910	COG0004	ammonium transporteR
KU053_RS03915	COG0583	DNA-binding transcription factor activity
KU053_RS03935	COG0525	valine-tRNA ligase activity
KU053_RS03945	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS03955	COG0393	Putative heavy-metal-binding
KU053_RS03960	COG0393	Putative heavy-metal-binding
KU053_RS03965	COG1538	Outer membrane efflux protein
KU053_RS03975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU053_RS03980	COG0671	phosphoesterase, PA-phosphatase related
KU053_RS04010	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KU053_RS04025	COG1648	precorrin-2 dehydrogenase activity
KU053_RS04025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KU053_RS04030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KU053_RS04035	COG1733	regulation of RNA biosynthetic process
KU053_RS04045	COG0531	amino acid
KU053_RS04060	COG0321	lipoyl(octanoyl) transferase activity
KU053_RS04065	COG2921	Belongs to the UPF0250 family
KU053_RS04105	COG2009	succinate dehydrogenase
KU053_RS04110	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KU053_RS04115	COG1053	succinate dehydrogenase
KU053_RS04120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KU053_RS04145	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU053_RS04165	COG2354	Protein conserved in bacteria
KU053_RS04170	COG2321	neutral zinc metallopeptidase
KU053_RS04190	COG2843	Capsule synthesis protein
KU053_RS04205	COG0589	response to stress
KU053_RS04225	COG0505	Belongs to the CarA family
KU053_RS04250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU053_RS04255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KU053_RS04305	COG0477	Major facilitator Superfamily
KU053_RS04310	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KU053_RS04325	COG1597	lipid kinase activity
KU053_RS04330	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU053_RS04355	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU053_RS04360	COG0584	glycerophosphoryl diester phosphodiesterase
KU053_RS04380	COG0741	lytic transglycosylase activity
KU053_RS04400	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KU053_RS04415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU053_RS04445	COG0778	Nitroreductase
KU053_RS04460	COG1929	Belongs to the glycerate kinase type-1 family
KU053_RS04465	COG0243	molybdopterin cofactor binding
KU053_RS04470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KU053_RS04475	COG3339	Conserved Protein
KU053_RS04485	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KU053_RS04500	COG1113	amino acid transport
KU053_RS04510	COG0019	diaminopimelate decarboxylase activity
KU053_RS04520	COG1280	lysine exporter protein (LysE YggA)
KU053_RS04525	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU053_RS04555	COG0463	Glycosyl transferase, family 2
KU053_RS04575	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU053_RS04610	COG4591	ABC-type transport system involved in lipoprotein release permease component
KU053_RS04615	COG1136	(ABC) transporter
KU053_RS04620	COG0658	competence protein
KU053_RS04620	COG2333	competence protein COMEC
KU053_RS04630	COG0616	signal peptide processing
KU053_RS04630	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KU053_RS04635	COG0596	Alpha beta hydrolase
KU053_RS04640	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KU053_RS04650	COG0628	permease
KU053_RS04685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU053_RS04705	COG0823	Involved in the tonB-independent uptake of proteins
KU053_RS04725	COG0824	Thioesterase
KU053_RS04730	COG1473	amidohydrolase
KU053_RS04750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KU053_RS04750	COG0047	phosphoribosylformylglycinamidine synthase activity
KU053_RS04755	COG2814	Major facilitator Superfamily
KU053_RS04765	COG1024	Enoyl-CoA hydratase
KU053_RS04770	COG1051	belongs to the nudix hydrolase family
KU053_RS04770	COG1056	cytidyltransferase-related domain
KU053_RS04780	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KU053_RS04795	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KU053_RS04810	COG4625	pathogenesis
KU053_RS04815	COG0583	DNA-binding transcription factor activity
KU053_RS04820	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KU053_RS04825	COG4208	sulfate ABC transporter
KU053_RS04830	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KU053_RS04840	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KU053_RS04845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KU053_RS04850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KU053_RS04870	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU053_RS04885	COG0681	Belongs to the peptidase S26 family
KU053_RS04900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KU053_RS04910	COG1381	Involved in DNA repair and RecF pathway recombination
KU053_RS04915	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KU053_RS04925	COG4221	oxidoreductase activity
KU053_RS04955	COG0436	Aminotransferase
KU053_RS04975	COG0556	nucleotide-excision repair
KU053_RS05030	COG2070	2-Nitropropane dioxygenase
KU053_RS05060	COG1215	transferase activity, transferring glycosyl groups
KU053_RS05075	COG0415	Belongs to the DNA photolyase family
KU053_RS05085	COG1252	NADH dehydrogenase
KU053_RS05090	COG1686	Belongs to the peptidase S11 family
KU053_RS05105	COG1187	pseudouridine synthase activity
KU053_RS05130	COG0477	Major facilitator Superfamily
KU053_RS05135	COG0583	DNA-binding transcription factor activity
KU053_RS05140	COG1823	symporter activity
KU053_RS05150	COG0612	Peptidase, M16
KU053_RS05175	COG0352	thiamine-phosphate diphosphorylase activity
KU053_RS05210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU053_RS05225	COG1309	transcriptional regulator
KU053_RS05235	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU053_RS05240	COG0076	glutamate decarboxylase activity
KU053_RS05250	COG1522	sequence-specific DNA binding
KU053_RS05255	COG3961	Belongs to the TPP enzyme family
KU053_RS05260	COG1113	amino acid transport
KU053_RS05265	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU053_RS05270	COG0573	inorganic phosphate transmembrane transporter activity
KU053_RS05280	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KU053_RS05285	COG0616	signal peptide processing
KU053_RS05320	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KU053_RS05325	COG1686	Belongs to the peptidase S11 family
KU053_RS05350	COG0583	DNA-binding transcription factor activity
KU053_RS05355	COG1067	ATP-dependent peptidase activity
KU053_RS05400	COG1966	Carbon starvation protein
KU053_RS05405	COG2879	small protein
KU053_RS05440	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KU053_RS05440	COG2508	Transcriptional regulator
KU053_RS05460	COG1113	amino acid transport
KU053_RS05465	COG0583	DNA-binding transcription factor activity
KU053_RS05470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU053_RS05475	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU053_RS05485	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS05495	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU053_RS05500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU053_RS05500	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KU053_RS05535	COG2814	Major facilitator Superfamily
KU053_RS05540	COG4948	Mandelate Racemase Muconate Lactonizing
KU053_RS05550	COG1309	transcriptional regulator
KU053_RS05570	COG1741	Belongs to the pirin family
KU053_RS05580	COG2964	Protein conserved in bacteria
KU053_RS05595	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU053_RS05600	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU053_RS05605	COG4605	iron ion homeostasis
KU053_RS05610	COG4604	ABC transporter, ATP-binding protein
KU053_RS05615	COG4607	ABC-type enterochelin transport system periplasmic component
KU053_RS05620	COG4774	siderophore transport
KU053_RS05630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU053_RS05635	COG1021	2,3-dihydroxybenzoate-AMP ligase
KU053_RS05640	COG1535	isochorismatase
KU053_RS05640	COG3433	isochorismatase activity
KU053_RS05655	COG1132	(ABC) transporter
KU053_RS05660	COG1132	(ABC) transporter
KU053_RS05665	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KU053_RS05675	COG1169	isochorismate synthase
KU053_RS05690	COG3739	integral membrane protein
KU053_RS05715	COG0302	gtp cyclohydrolase
KU053_RS05725	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KU053_RS05755	COG0308	aminopeptidase N
KU053_RS05760	COG0512	Glutamine amidotransferase of anthranilate synthase
KU053_RS05950	COG5410	chromosome segregation
KU053_RS06120	COG0582	viral genome integration into host DNA
KU053_RS06135	COG0174	glutamine synthetase
KU053_RS06145	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KU053_RS06180	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KU053_RS06185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KU053_RS06190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU053_RS06210	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU053_RS06215	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KU053_RS06220	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KU053_RS06235	COG1960	acyl-CoA dehydrogenase activity
KU053_RS06240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU053_RS06245	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU053_RS06255	COG2223	nitrite transmembrane transporter activity
KU053_RS06265	COG0024	Methionine aminopeptidase
KU053_RS06270	COG0052	Belongs to the universal ribosomal protein uS2 family
KU053_RS06285	COG2207	Transcriptional regulator
KU053_RS06310	COG2951	lytic endotransglycosylase activity
KU053_RS06315	COG0772	Belongs to the SEDS family
KU053_RS06330	COG0842	Transport permease protein
KU053_RS06335	COG1131	(ABC) transporter
KU053_RS06380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU053_RS06395	COG4215	(ABC) transporter
KU053_RS06400	COG4160	amino acid transport
KU053_RS06405	COG4598	ABC transporter
KU053_RS06415	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU053_RS06420	COG0826	peptidase U32
KU053_RS06425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU053_RS06440	COG1720	tRNA m6t6A37 methyltransferase activity
KU053_RS06450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KU053_RS06465	COG0642	Histidine kinase
KU053_RS06475	COG0494	nUDIX hydrolase
KU053_RS06485	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KU053_RS06490	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KU053_RS06495	COG3139	Protein of unknown function (DUF1315)
KU053_RS06500	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KU053_RS06505	COG1301	dicarboxylic acid transport
KU053_RS06510	COG1960	acyl-CoA dehydrogenase activity
KU053_RS06515	COG2819	hydrolase of the alpha beta superfamily
KU053_RS06525	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KU053_RS06535	COG2195	Cleaves the N-terminal amino acid of tripeptides
KU053_RS06540	COG1234	tRNA 3'-trailer cleavage
KU053_RS06570	COG2363	Small membrane protein
KU053_RS06595	COG0513	Belongs to the DEAD box helicase family
KU053_RS06605	COG0778	Nitroreductase
KU053_RS06635	COG1286	toxin biosynthetic process
KU053_RS06660	COG4783	chaperone-mediated protein folding
KU053_RS06665	COG1610	YqeY-like protein
KU053_RS06765	COG3111	PFAM Bacterial OB fold (BOF) protein
KU053_RS06790	COG3243	poly(R)-hydroxyalkanoic acid synthase
KU053_RS06795	COG0786	glutamate:sodium symporter activity
KU053_RS06805	COG2186	Transcriptional regulator
KU053_RS06855	COG0477	Major facilitator Superfamily
KU053_RS06890	COG2985	domain, Protein
KU053_RS06900	COG2995	paraquat-inducible protein a
KU053_RS06905	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KU053_RS06905	COG3008	intermembrane lipid transfer
KU053_RS06915	COG1794	racemase activity, acting on amino acids and derivatives
KU053_RS06990	COG1301	dicarboxylic acid transport
KU053_RS07000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU053_RS07005	COG2011	ABC-type metal ion transport system permease component
KU053_RS07010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU053_RS07015	COG1464	Belongs to the NlpA lipoprotein family
KU053_RS07020	COG0151	Belongs to the GarS family
KU053_RS07025	COG0138	bifunctional purine biosynthesis protein purh
KU053_RS07030	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KU053_RS07060	COG2308	Evidence 4 Homologs of previously reported genes of
KU053_RS07070	COG1305	Transglutaminase-like
KU053_RS07080	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KU053_RS07085	COG0305	Participates in initiation and elongation during chromosome replication
KU053_RS07110	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KU053_RS07120	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KU053_RS07125	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KU053_RS07150	COG1649	PFAM Uncharacterised BCR, COG1649
KU053_RS07150	COG0726	polysaccharide deacetylase
KU053_RS07155	COG1215	transferase activity, transferring glycosyl groups
KU053_RS07160	COG3658	cytochrome
KU053_RS07170	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU053_RS07185	COG0583	DNA-binding transcription factor activity
KU053_RS07205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU053_RS07210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU053_RS07225	COG1960	acyl-CoA dehydrogenase activity
KU053_RS07230	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU053_RS07235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU053_RS07260	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KU053_RS07265	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KU053_RS07275	COG2205	protein histidine kinase activity
KU053_RS07280	COG0745	RESPONSE REGULATOR receiver
KU053_RS07285	COG0174	glutamine synthetase
KU053_RS07305	COG0729	surface antigen
KU053_RS07330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU053_RS07335	COG2814	Major facilitator Superfamily
KU053_RS07350	COG0583	DNA-binding transcription factor activity
KU053_RS07365	COG1187	pseudouridine synthase activity
KU053_RS07385	COG0802	atpase or kinase
KU053_RS07390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KU053_RS07400	COG1923	regulation of RNA biosynthetic process
KU053_RS07405	COG0697	spore germination
KU053_RS07420	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU053_RS07430	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU053_RS07435	COG0519	Catalyzes the synthesis of GMP from XMP
KU053_RS07435	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU053_RS07440	COG4302	ethanolamine ammonia-lyase activity
KU053_RS07445	COG4303	Ethanolamine ammonia lyase large subunit
KU053_RS07450	COG0531	amino acid
KU053_RS07470	COG1454	alcohol dehydrogenase
KU053_RS07475	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU053_RS07485	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KU053_RS07505	COG0308	aminopeptidase N
KU053_RS07515	COG4221	oxidoreductase activity
KU053_RS07525	COG1605	Chorismate mutase
KU053_RS07545	COG1309	transcriptional regulator
KU053_RS07555	COG0668	transmembrane transport
KU053_RS07590	COG4773	Receptor
KU053_RS07610	COG0488	(ABC) transporter
KU053_RS07615	COG0589	response to stress
KU053_RS07640	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KU053_RS07650	COG3135	benzoate transporter
KU053_RS07655	COG1522	sequence-specific DNA binding
KU053_RS07665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KU053_RS07670	COG0583	DNA-binding transcription factor activity
KU053_RS07680	COG0183	Belongs to the thiolase family
KU053_RS07690	COG2030	dehydratase
KU053_RS07695	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU053_RS07710	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KU053_RS07720	COG0824	Thioesterase
KU053_RS07725	COG1454	alcohol dehydrogenase
KU053_RS07735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KU053_RS07755	COG0069	glutamate synthase activity
KU053_RS07775	COG2814	Major facilitator Superfamily
KU053_RS07790	COG0511	ligase activity, forming carbon-carbon bonds
KU053_RS07810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU053_RS07810	COG1116	anion transmembrane transporter activity
KU053_RS07815	COG0745	RESPONSE REGULATOR receiver
KU053_RS07825	COG2146	nitrite reductase [NAD(P)H] activity
KU053_RS07825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU053_RS07830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU053_RS07835	COG0243	molybdopterin cofactor binding
KU053_RS07845	COG0243	molybdopterin cofactor binding
KU053_RS07850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KU053_RS07865	COG0521	Mo-molybdopterin cofactor biosynthetic process
KU053_RS07865	COG0315	cyclic pyranopterin monophosphate synthase activity
KU053_RS07870	COG0303	'Molybdopterin
KU053_RS07880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU053_RS07885	COG0697	spore germination
KU053_RS07905	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KU053_RS07910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU053_RS07965	COG2204	response regulator
KU053_RS07970	COG3852	Histidine kinase
KU053_RS07990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KU053_RS07995	COG0575	Belongs to the CDS family
KU053_RS08030	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU053_RS08045	COG2137	regulation of response to DNA damage stimulus
KU053_RS08055	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KU053_RS08060	COG1011	Hydrolase
KU053_RS08085	COG1522	sequence-specific DNA binding
KU053_RS08095	COG1113	amino acid transport
KU053_RS08115	COG0659	secondary active sulfate transmembrane transporter activity
KU053_RS08120	COG2135	peptidase activity
KU053_RS08135	COG3300	MHYT domain
KU053_RS08135	COG5001	Diguanylate cyclase
KU053_RS08155	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU053_RS08155	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU053_RS08155	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KU053_RS08160	COG1105	Belongs to the carbohydrate kinase PfkB family
KU053_RS08165	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU053_RS08165	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KU053_RS08195	COG0024	Methionine aminopeptidase
KU053_RS08200	COG0583	DNA-binding transcription factor activity
KU053_RS08210	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KU053_RS08215	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU053_RS08220	COG0517	IMP dehydrogenase activity
KU053_RS08220	COG0516	GMP reductase activity
KU053_RS08245	COG0552	protein localization to endoplasmic reticulum
KU053_RS08255	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KU053_RS08270	COG4890	Cyd operon protein YbgT
KU053_RS08275	COG1294	oxidase, subunit
KU053_RS08290	COG1585	Membrane protein implicated in regulation of membrane protease activity
KU053_RS08300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU053_RS08305	COG4774	siderophore transport
KU053_RS08320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KU053_RS08325	COG0569	domain protein
KU053_RS08330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU053_RS08360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KU053_RS08365	COG0542	response to heat
KU053_RS08390	COG1902	pentaerythritol trinitrate reductase activity
KU053_RS08390	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU053_RS08435	COG2323	membrane
KU053_RS08440	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KU053_RS08450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU053_RS08455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU053_RS08460	COG0183	Belongs to the thiolase family
KU053_RS08465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KU053_RS08470	COG0596	Alpha beta hydrolase
KU053_RS08475	COG2271	Major facilitator Superfamily
KU053_RS08480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU053_RS08485	COG3485	protocatechuate 3,4-dioxygenase
KU053_RS08490	COG3485	protocatechuate 3,4-dioxygenase
KU053_RS08495	COG0710	3-dehydroquinate dehydratase activity
KU053_RS08500	COG3420	alginic acid biosynthetic process
KU053_RS08505	COG3659	wide pore channel activity
KU053_RS08510	COG4993	Dehydrogenase
KU053_RS08520	COG2391	methyltransferase activity
KU053_RS08535	COG1414	Transcriptional regulator
KU053_RS08540	COG0583	DNA-binding transcription factor activity
KU053_RS08545	COG1960	acyl-CoA dehydrogenase activity
KU053_RS08570	COG2814	Major facilitator Superfamily
KU053_RS08580	COG0154	amidase activity
KU053_RS08600	COG4638	Rieske (2fe-2S)
KU053_RS08610	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS08620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU053_RS08630	COG3733	amine oxidase
KU053_RS08640	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS08650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU053_RS08655	COG0183	Belongs to the thiolase family
KU053_RS08660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU053_RS08665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU053_RS08675	COG4829	muconolactone delta-isomerase
KU053_RS08680	COG4948	Mandelate Racemase Muconate Lactonizing
KU053_RS08685	COG0583	DNA-binding transcription factor activity
KU053_RS08695	COG2186	Transcriptional regulator
KU053_RS08715	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS08735	COG1960	acyl-CoA dehydrogenase activity
KU053_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS08745	COG3829	transcription factor binding
KU053_RS08755	COG3162	membrane
KU053_RS08770	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS08785	COG0753	catalase activity
KU053_RS08805	COG1846	Transcriptional regulator
KU053_RS08810	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU053_RS08810	COG1902	pentaerythritol trinitrate reductase activity
KU053_RS08820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KU053_RS08850	COG1309	transcriptional regulator
KU053_RS08860	COG1335	isochorismatase
KU053_RS08865	COG0583	DNA-binding transcription factor activity
KU053_RS08875	COG0475	glutathione-regulated potassium exporter activity
KU053_RS08875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU053_RS08885	COG1473	amidohydrolase
KU053_RS08895	COG2831	hemolysin activation secretion protein
KU053_RS08900	COG3210	domain, Protein
KU053_RS08930	COG2188	Transcriptional regulator
KU053_RS08945	COG0583	DNA-binding transcription factor activity
KU053_RS08975	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU053_RS09005	COG1566	PFAM secretion protein HlyD family protein
KU053_RS09020	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS09025	COG0129	dihydroxy-acid dehydratase activity
KU053_RS09035	COG0583	DNA-binding transcription factor activity
KU053_RS09040	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU053_RS09050	COG2084	Dehydrogenase
KU053_RS09055	COG2207	Transcriptional regulator
KU053_RS09070	COG1064	alcohol dehydrogenase
KU053_RS09080	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU053_RS09085	COG1120	ATPase activity
KU053_RS09105	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU053_RS09225	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KU053_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS09290	COG2207	Transcriptional regulator
KU053_RS09300	COG2205	protein histidine kinase activity
KU053_RS09305	COG0745	RESPONSE REGULATOR receiver
KU053_RS09310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU053_RS09315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU053_RS09320	COG1538	Outer membrane efflux protein
KU053_RS09330	COG2072	flavoprotein involved in K transport
KU053_RS09350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU053_RS09370	COG3539	Fimbrial protein
KU053_RS09400	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KU053_RS09410	COG0753	catalase activity
KU053_RS09425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU053_RS09485	COG3433	isochorismatase activity
KU053_RS09485	COG1535	isochorismatase
KU053_RS09490	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS09495	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KU053_RS09500	COG4149	molybdate abc transporter
KU053_RS09505	COG0725	ABC transporter, periplasmic molybdate-binding protein
KU053_RS09515	COG4638	Rieske (2fe-2S)
KU053_RS09520	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU053_RS09525	COG0543	2 iron, 2 sulfur cluster binding
KU053_RS09525	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU053_RS09550	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS09565	COG2207	Transcriptional regulator
KU053_RS09575	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS09580	COG2610	gluconate transmembrane transporter activity
KU053_RS09590	COG0583	DNA-binding transcription factor activity
KU053_RS09600	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU053_RS09605	COG2031	fatty acid transporter
KU053_RS09610	COG0183	Belongs to the thiolase family
KU053_RS09615	COG0583	DNA-binding transcription factor activity
KU053_RS09620	COG0583	DNA-binding transcription factor activity
KU053_RS09635	COG1027	Aspartate ammonia-lyase
KU053_RS09645	COG0477	Major facilitator Superfamily
KU053_RS09665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU053_RS09670	COG4521	taurine ABC transporter
KU053_RS09685	COG2188	Transcriptional regulator
KU053_RS09695	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KU053_RS09700	COG1733	regulation of RNA biosynthetic process
KU053_RS09705	COG3708	Transcriptional regulator
KU053_RS09705	COG2207	Transcriptional regulator
KU053_RS09720	COG0730	response to heat
KU053_RS09735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU053_RS09735	COG3453	Protein conserved in bacteria
KU053_RS09745	COG3781	membrane
KU053_RS09750	COG1063	alcohol dehydrogenase
KU053_RS09760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU053_RS09765	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU053_RS09770	COG0022	dehydrogenase e1 component
KU053_RS09775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KU053_RS09780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU053_RS09795	COG3706	GGDEF domain
KU053_RS09810	COG0133	tryptophan synthase activity
KU053_RS09820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU053_RS09855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KU053_RS09880	COG2226	methyltransferase
KU053_RS09935	COG0842	Transport permease protein
KU053_RS09940	COG0842	Transport permease protein
KU053_RS09945	COG1131	(ABC) transporter
KU053_RS09960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU053_RS09965	COG4773	Receptor
KU053_RS09985	COG0730	response to heat
KU053_RS09990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KU053_RS10010	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KU053_RS10025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU053_RS10065	COG4264	IucA IucC family
KU053_RS10070	COG4264	IucA IucC family
KU053_RS10090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KU053_RS10105	COG1960	acyl-CoA dehydrogenase activity
KU053_RS10110	COG1960	acyl-CoA dehydrogenase activity
KU053_RS10115	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU053_RS10120	COG2207	Transcriptional regulator
KU053_RS10125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU053_RS10130	COG0776	regulation of translation
KU053_RS10155	COG0822	iron-sulfur transferase activity
KU053_RS10160	COG0316	Belongs to the HesB IscA family
KU053_RS10190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KU053_RS10210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU053_RS10215	COG0702	epimerase
KU053_RS10250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU053_RS10260	COG0339	signal peptide processing
KU053_RS10310	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KU053_RS10315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KU053_RS10345	COG0776	regulation of translation
KU053_RS10410	COG0084	hydrolase, TatD family'
KU053_RS10430	COG1663	tetraacyldisaccharide 4'-kinase activity
KU053_RS10435	COG1132	(ABC) transporter
KU053_RS10445	COG0811	peptide transport
KU053_RS10450	COG1475	DNA binding
KU053_RS10455	COG1192	Involved in chromosome partitioning
KU053_RS10465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU053_RS10480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU053_RS10485	COG0191	fructose-bisphosphate aldolase activity
KU053_RS10505	COG0424	maF-like protein
KU053_RS10510	COG2850	peptidyl-arginine hydroxylation
KU053_RS10520	COG0640	Transcriptional regulator
KU053_RS10530	COG3619	membrane
KU053_RS10535	COG3122	Protein conserved in bacteria
KU053_RS10540	COG1132	(ABC) transporter
KU053_RS10560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KU053_RS10565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU053_RS10575	COG0506	proline dehydrogenase activity
KU053_RS10575	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU053_RS10575	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU053_RS10580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KU053_RS10595	COG3698	Phosphodiester glycosidase
KU053_RS10605	COG2353	YceI-like domain
KU053_RS10620	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KU053_RS10665	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KU053_RS10665	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KU053_RS10690	COG3539	Fimbrial protein
KU053_RS10695	COG3121	Chaperone
KU053_RS10720	COG0697	spore germination
KU053_RS10730	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU053_RS10740	COG0583	DNA-binding transcription factor activity
KU053_RS10760	COG1309	transcriptional regulator
KU053_RS10775	COG1522	sequence-specific DNA binding
KU053_RS10785	COG1126	abc transporter atp-binding protein
KU053_RS10790	COG0765	amino acid transport
KU053_RS10795	COG0765	amino acid transport
KU053_RS10825	COG1464	Belongs to the NlpA lipoprotein family
KU053_RS10835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU053_RS10840	COG2011	ABC-type metal ion transport system permease component
KU053_RS10845	COG0012	GTP binding
KU053_RS10870	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU053_RS10910	COG0386	Belongs to the glutathione peroxidase family
KU053_RS10920	COG0436	Aminotransferase
KU053_RS10960	COG3634	alkyl hydroperoxide reductase activity
KU053_RS10975	COG0583	DNA-binding transcription factor activity
KU053_RS10980	COG0798	PFAM Bile acid sodium symporter
KU053_RS10985	COG0640	Transcriptional regulator
KU053_RS11000	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KU053_RS11010	COG0583	DNA-binding transcription factor activity
KU053_RS11020	COG1953	Uracil, thiamine, allantoin
KU053_RS11030	COG2175	clavaminate synthase activity
KU053_RS11035	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU053_RS11040	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KU053_RS11045	COG4521	taurine ABC transporter
KU053_RS11055	COG0477	Major facilitator Superfamily
KU053_RS11075	COG1271	oxidase subunit
KU053_RS11080	COG1294	oxidase, subunit
KU053_RS11090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU053_RS11110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KU053_RS11130	COG3052	prosthetic group binding
KU053_RS11135	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KU053_RS11145	COG2814	Major facilitator Superfamily
KU053_RS11165	COG1346	cytolysis
KU053_RS11175	COG0583	DNA-binding transcription factor activity
KU053_RS11180	COG0625	glutathione transferase activity
KU053_RS11185	COG0625	glutathione transferase activity
KU053_RS11190	COG0583	DNA-binding transcription factor activity
KU053_RS11205	COG1045	serine acetyltransferase
KU053_RS11210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU053_RS11215	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KU053_RS11225	COG1280	lysine exporter protein (LysE YggA)
KU053_RS11240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU053_RS11245	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU053_RS11250	COG1126	abc transporter atp-binding protein
KU053_RS11255	COG0765	amino acid transport
KU053_RS11260	COG0765	amino acid transport
KU053_RS11280	COG0784	Response regulator, receiver
KU053_RS11280	COG2205	protein histidine kinase activity
KU053_RS11300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU053_RS11320	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS11370	COG0583	DNA-binding transcription factor activity
KU053_RS11390	COG0318	PFAM AMP-dependent synthetase and ligase
KU053_RS11395	COG1309	transcriptional regulator
KU053_RS11400	COG1960	acyl-CoA dehydrogenase activity
KU053_RS11405	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU053_RS11410	COG1024	Enoyl-CoA hydratase
KU053_RS11415	COG4770	biotin carboxylase activity
KU053_RS11425	COG0583	DNA-binding transcription factor activity
KU053_RS11440	COG1960	acyl-CoA dehydrogenase activity
KU053_RS11450	COG2814	Major facilitator Superfamily
KU053_RS11460	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU053_RS11465	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU053_RS11470	COG2814	Major facilitator Superfamily
KU053_RS11475	COG1960	acyl-CoA dehydrogenase activity
KU053_RS11480	COG1024	Enoyl-CoA hydratase
KU053_RS11485	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS11490	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU053_RS11495	COG0183	Belongs to the thiolase family
KU053_RS11505	COG2814	Major facilitator Superfamily
KU053_RS11515	COG1024	Enoyl-CoA hydratase
KU053_RS11530	COG1960	acyl-CoA dehydrogenase activity
KU053_RS11535	COG2814	Major facilitator Superfamily
KU053_RS11540	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU053_RS11545	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KU053_RS11560	COG3842	ATPase activity
KU053_RS11565	COG1840	ABC-type Fe3 transport system, periplasmic component
KU053_RS11575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU053_RS11580	COG1414	Transcriptional regulator
KU053_RS11590	COG0583	DNA-binding transcription factor activity
KU053_RS11595	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU053_RS11600	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS11610	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU053_RS11620	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS11625	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU053_RS11630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU053_RS11635	COG2267	carboxylic ester hydrolase activity
KU053_RS11655	COG3038	cytochrome b561
KU053_RS11660	COG0753	catalase activity
KU053_RS11695	COG2050	protein possibly involved in aromatic compounds catabolism
KU053_RS11705	COG3327	negative regulation of DNA-templated transcription, initiation
KU053_RS11710	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KU053_RS11715	COG0183	Belongs to the thiolase family
KU053_RS11720	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU053_RS11725	COG1024	Enoyl-CoA hydratase
KU053_RS11730	COG1024	Enoyl-CoA hydratase
KU053_RS11735	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU053_RS11740	COG2151	metal-sulfur cluster biosynthetic enzyme
KU053_RS11745	COG3396	Phenylacetate-CoA oxygenase
KU053_RS11750	COG3460	Phenylacetate-CoA oxygenase
KU053_RS11755	COG3396	Phenylacetate-CoA oxygenase
KU053_RS11760	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS11760	COG2030	dehydratase
KU053_RS11765	COG1760	l-serine dehydratase
KU053_RS11770	COG0531	amino acid
KU053_RS11775	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS11790	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU053_RS11800	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU053_RS11820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU053_RS11830	COG0789	Transcriptional regulator
KU053_RS11845	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KU053_RS11860	COG2807	transmembrane transport
KU053_RS11865	COG0590	tRNA wobble adenosine to inosine editing
KU053_RS11985	COG1116	anion transmembrane transporter activity
KU053_RS11990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU053_RS12000	COG0864	Transcriptional regulator
KU053_RS12020	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU053_RS12025	COG0439	Biotin carboxylase
KU053_RS12040	COG1063	alcohol dehydrogenase
KU053_RS12050	COG1309	transcriptional regulator
KU053_RS12070	COG0038	chloride channel
KU053_RS12075	COG4770	biotin carboxylase activity
KU053_RS12095	COG1914	H( )-stimulated, divalent metal cation uptake system
KU053_RS12100	COG0583	DNA-binding transcription factor activity
KU053_RS12150	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU053_RS12170	COG2814	Major facilitator Superfamily
KU053_RS12185	COG1560	Kdo2-lipid A biosynthetic process
KU053_RS12195	COG5006	permease, DMT superfamily
KU053_RS12200	COG1522	sequence-specific DNA binding
KU053_RS12215	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KU053_RS12225	COG4122	O-methyltransferase activity
KU053_RS12255	COG1538	Outer membrane efflux protein
KU053_RS12260	COG1137	ATPase activity
KU053_RS12265	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KU053_RS12275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KU053_RS12280	COG0517	IMP dehydrogenase activity
KU053_RS12280	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU053_RS12315	COG2814	Major facilitator Superfamily
KU053_RS12350	COG1278	Cold shock
KU053_RS12355	COG1280	lysine exporter protein (LysE YggA)
KU053_RS12385	COG1570	exodeoxyribonuclease VII activity
KU053_RS12435	COG0583	DNA-binding transcription factor activity
KU053_RS12445	COG4638	Rieske (2fe-2S)
KU053_RS12465	COG0633	Ferredoxin
KU053_RS12465	COG0543	2 iron, 2 sulfur cluster binding
KU053_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS12475	COG3135	benzoate transporter
KU053_RS12480	COG2814	Major facilitator Superfamily
KU053_RS12495	COG1643	Atp-dependent helicase
KU053_RS12500	COG0450	alkyl hydroperoxide reductase
KU053_RS12510	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KU053_RS12520	COG3634	alkyl hydroperoxide reductase activity
KU053_RS12540	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KU053_RS12545	COG0625	glutathione transferase activity
KU053_RS12555	COG2885	chlorophyll binding
KU053_RS12590	COG0542	response to heat
KU053_RS12605	COG1765	OsmC-like protein
KU053_RS12625	COG0667	Aldo Keto reductase
KU053_RS12640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KU053_RS12650	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KU053_RS12660	COG0527	aspartate kinase activity
KU053_RS12670	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KU053_RS12680	COG3038	cytochrome b561
KU053_RS12685	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KU053_RS12690	COG2252	PERMEase
KU053_RS12700	COG2072	flavoprotein involved in K transport
KU053_RS12715	COG1741	Belongs to the pirin family
KU053_RS12720	COG1309	transcriptional regulator
KU053_RS12730	COG0300	oxidoreductase activity
KU053_RS12845	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KU053_RS12895	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS12915	COG0531	amino acid
KU053_RS12925	COG1113	amino acid transport
KU053_RS12965	COG3209	COG3209 Rhs family protein
KU053_RS12995	COG4269	membrane
KU053_RS13010	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU053_RS13010	COG1902	pentaerythritol trinitrate reductase activity
KU053_RS13020	COG2203	Gaf domain
KU053_RS13020	COG3706	GGDEF domain
KU053_RS13020	COG4251	negative regulation of phosphorylation
KU053_RS13020	COG5001	Diguanylate cyclase
KU053_RS13030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU053_RS13050	COG4172	Belongs to the ABC transporter superfamily
KU053_RS13055	COG4239	(ABC) transporter, permease
KU053_RS13060	COG4174	ABC transporter (Permease)
KU053_RS13070	COG1388	LysM domain
KU053_RS13070	COG0741	lytic transglycosylase activity
KU053_RS13070	COG1388	LysM domain
KU053_RS13070	COG0741	lytic transglycosylase activity
KU053_RS13075	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU053_RS13115	COG0583	DNA-binding transcription factor activity
KU053_RS13120	COG1279	arginine transmembrane transporter activity
KU053_RS13140	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU053_RS13145	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU053_RS13150	COG0006	proline dipeptidase activity
KU053_RS13190	COG2194	sulfuric ester hydrolase activity
KU053_RS13235	COG0739	heme binding
KU053_RS13560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KU053_RS13580	COG3384	dioxygenase
KU053_RS13590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU053_RS13595	COG2878	Part of a membrane complex involved in electron transport
KU053_RS13600	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KU053_RS13625	COG0768	penicillin binding
KU053_RS13630	COG0742	ribosomal rna small subunit methyltransferase
KU053_RS13645	COG0830	nickel cation binding
KU053_RS13655	COG0804	urea catabolic process
KU053_RS13695	COG1253	flavin adenine dinucleotide binding
KU053_RS13700	COG2851	Citrate transporter
KU053_RS13750	COG1773	rubredoxin
KU053_RS13755	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU053_RS13765	COG0583	DNA-binding transcription factor activity
KU053_RS13790	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KU053_RS13795	COG4181	ATPase activity
KU053_RS13840	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KU053_RS13860	COG0306	phosphate transporter
KU053_RS13870	COG3958	Transketolase
KU053_RS13875	COG3959	Transketolase, thiamine diphosphate binding domain
KU053_RS13880	COG2271	Major facilitator Superfamily
KU053_RS13885	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS13890	COG0583	DNA-binding transcription factor activity
KU053_RS13905	COG2223	nitrite transmembrane transporter activity
KU053_RS13910	COG2207	Transcriptional regulator
KU053_RS13915	COG2066	Belongs to the glutaminase family
KU053_RS13920	COG0242	peptide deformylase activity
KU053_RS13925	COG0477	Major facilitator Superfamily
KU053_RS13935	COG0028	Belongs to the TPP enzyme family
KU053_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS13955	COG2267	carboxylic ester hydrolase activity
KU053_RS13965	COG2271	Major facilitator Superfamily
KU053_RS13970	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU053_RS13980	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS14000	COG1414	Transcriptional regulator
KU053_RS14015	COG1024	Enoyl-CoA hydratase
KU053_RS14025	COG1215	transferase activity, transferring glycosyl groups
KU053_RS14030	COG0726	polysaccharide deacetylase
KU053_RS14030	COG1649	PFAM Uncharacterised BCR, COG1649
KU053_RS14040	COG4681	YaeQ
KU053_RS14050	COG0523	cobalamin synthesis protein
KU053_RS14060	COG1607	acyl-coa hydrolase
KU053_RS14070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU053_RS14075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU053_RS14080	COG1309	transcriptional regulator
KU053_RS14105	COG2040	homocysteine
KU053_RS14110	COG0531	amino acid
KU053_RS14135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU053_RS14140	COG0477	Major facilitator Superfamily
KU053_RS14260	COG0592	DNA-directed DNA polymerase activity
KU053_RS14300	COG2026	Addiction module toxin, RelE StbE family
KU053_RS14450	COG3755	Protein conserved in bacteria
KU053_RS14495	COG1484	DNA-dependent DNA replication
KU053_RS14585	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU053_RS14655	COG0405	Gamma-glutamyltransferase
KU053_RS14660	COG2814	Major facilitator Superfamily
KU053_RS14670	COG2050	protein possibly involved in aromatic compounds catabolism
KU053_RS14685	COG1090	epimerase
KU053_RS14705	COG0420	3'-5' exonuclease activity
KU053_RS14730	COG0735	belongs to the Fur family
KU053_RS14735	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU053_RS14755	COG0121	glutamine amidotransferase
KU053_RS14770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU053_RS14780	COG0210	DNA helicase
KU053_RS14785	COG2885	chlorophyll binding
KU053_RS14790	COG0204	Acyl-transferase
KU053_RS14805	COG2894	cell division
KU053_RS14830	COG1280	lysine exporter protein (LysE YggA)
KU053_RS14835	COG1674	ftsk spoiiie
KU053_RS14835	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KU053_RS14840	COG0492	ferredoxin-NADP+ reductase activity
KU053_RS14845	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KU053_RS14855	COG0456	acetyltransferase
KU053_RS14900	COG1981	membrane
KU053_RS14915	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KU053_RS14915	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU053_RS14935	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS14945	COG0657	acetylesterase activity
KU053_RS14955	COG0473	3-isopropylmalate dehydrogenase activity
KU053_RS14960	COG0583	DNA-binding transcription factor activity
KU053_RS14980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU053_RS15005	COG0564	pseudouridine synthase activity
KU053_RS15015	COG0358	DNA primase activity
KU053_RS15030	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KU053_RS15060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU053_RS15090	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KU053_RS15100	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU053_RS15100	COG0352	thiamine-phosphate diphosphorylase activity
KU053_RS15100	COG0351	phosphomethylpyrimidine kinase
KU053_RS15105	COG1652	LysM domain
KU053_RS15130	COG1399	metal-binding, possibly nucleic acid-binding protein
KU053_RS15135	COG3101	peptidyl-lysine hydroxylation
KU053_RS15140	COG0009	L-threonylcarbamoyladenylate synthase
KU053_RS15145	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KU053_RS15150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KU053_RS15165	COG4106	trans-aconitate 2-methyltransferase activity
KU053_RS15180	COG0596	Alpha beta hydrolase
KU053_RS15180	COG2226	methyltransferase
KU053_RS15180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU053_RS15185	COG1877	trehalose-phosphatase activity
KU053_RS15190	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KU053_RS15195	COG2223	nitrite transmembrane transporter activity
KU053_RS15215	COG1196	nuclear chromosome segregation
KU053_RS15225	COG0730	response to heat
KU053_RS15240	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KU053_RS15250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU053_RS15300	COG0489	protein tyrosine kinase activity
KU053_RS15310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU053_RS15310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU053_RS15340	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KU053_RS15345	COG2081	HI0933 family
KU053_RS15355	COG0668	transmembrane transport
KU053_RS15375	COG0583	DNA-binding transcription factor activity
KU053_RS15395	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU053_RS15400	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU053_RS15430	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KU053_RS15470	COG0745	RESPONSE REGULATOR receiver
KU053_RS15490	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU053_RS15500	COG2205	protein histidine kinase activity
KU053_RS15580	COG4993	Dehydrogenase
KU053_RS15605	COG0384	phenazine biosynthesis protein PhzF
KU053_RS15630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU053_RS15645	COG0583	DNA-binding transcription factor activity
KU053_RS15675	COG0583	DNA-binding transcription factor activity
KU053_RS15690	COG0583	DNA-binding transcription factor activity
KU053_RS15695	COG1053	succinate dehydrogenase
KU053_RS15705	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU053_RS15710	COG2814	Major facilitator Superfamily
KU053_RS15715	COG1960	acyl-CoA dehydrogenase activity
KU053_RS15720	COG0583	DNA-binding transcription factor activity
KU053_RS15725	COG1063	alcohol dehydrogenase
KU053_RS15755	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KU053_RS15760	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KU053_RS15765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU053_RS15780	COG3667	copper resistance
KU053_RS15785	COG2132	Multicopper oxidase
KU053_RS15795	COG0561	phosphatase activity
KU053_RS15800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KU053_RS15825	COG1214	PFAM Peptidase M22, glycoprotease
KU053_RS15875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KU053_RS15885	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU053_RS15890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KU053_RS15895	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KU053_RS15955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU053_RS15965	COG1846	Transcriptional regulator
KU053_RS15970	COG1764	response to oxidative stress
KU053_RS16010	COG0037	tRNA processing
KU053_RS16020	COG0248	Ppx GppA phosphatase
KU053_RS16050	COG0072	phenylalanine-tRNA ligase activity
KU053_RS16095	COG1238	metal cluster binding
KU053_RS16100	COG0625	glutathione transferase activity
KU053_RS16115	COG0318	PFAM AMP-dependent synthetase and ligase
KU053_RS16120	COG3028	Belongs to the UPF0307 family
KU053_RS16125	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU053_RS16145	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KU053_RS16150	COG0617	tRNA 3'-terminal CCA addition
KU053_RS16155	COG1555	photosystem II stabilization
KU053_RS16160	COG3956	TIGRFAM MazG family protein
KU053_RS16170	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU053_RS16190	COG0784	Response regulator, receiver
KU053_RS16190	COG5002	protein histidine kinase activity
KU053_RS16190	COG2205	protein histidine kinase activity
KU053_RS16195	COG1024	Enoyl-CoA hydratase
KU053_RS16200	COG2084	Dehydrogenase
KU053_RS16205	COG3622	Belongs to the hyi family
KU053_RS16235	COG0697	spore germination
KU053_RS16245	COG2814	Major facilitator Superfamily
KU053_RS16250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU053_RS16260	COG0583	DNA-binding transcription factor activity
KU053_RS16270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KU053_RS16285	COG0084	hydrolase, TatD family'
KU053_RS16300	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KU053_RS16330	COG0440	acetolactate synthase activity
KU053_RS16335	COG0028	Belongs to the TPP enzyme family
KU053_RS16360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU053_RS16365	COG0577	efflux transmembrane transporter activity
KU053_RS16365	COG1136	(ABC) transporter
KU053_RS16370	COG1538	Outer membrane efflux protein
KU053_RS16385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KU053_RS16390	COG1162	GTPase activity
KU053_RS16400	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KU053_RS16420	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KU053_RS16425	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS16465	COG2986	histidine ammonia-lyase
KU053_RS16480	COG0318	PFAM AMP-dependent synthetase and ligase
KU053_RS16490	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU053_RS16535	COG1426	Protein conserved in bacteria
KU053_RS16570	COG0793	Belongs to the peptidase S41A family
KU053_RS16585	COG2267	carboxylic ester hydrolase activity
KU053_RS16595	COG1012	belongs to the aldehyde dehydrogenase family
KU053_RS16600	COG3265	gluconokinase activity
KU053_RS16610	COG0800	Aldolase
KU053_RS16620	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KU053_RS16625	COG0857	belongs to the CobB CobQ family
KU053_RS16625	COG0280	phosphate acetyltransferase
KU053_RS16630	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KU053_RS16630	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KU053_RS16650	COG0740	serine-type endopeptidase activity
KU053_RS16660	COG4774	siderophore transport
KU053_RS16670	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KU053_RS16680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU053_RS16680	COG2813	Specifically methylates the guanine in position
KU053_RS16780	COG0788	formyltetrahydrofolate deformylase activity
KU053_RS16805	COG4651	solute:proton antiporter activity
KU053_RS16805	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU053_RS16825	COG0724	RNA recognition motif
KU053_RS16830	COG0210	DNA helicase
KU053_RS16855	COG1733	regulation of RNA biosynthetic process
KU053_RS16865	COG2900	Belongs to the SlyX family
KU053_RS16870	COG0488	(ABC) transporter
KU053_RS16875	COG1280	lysine exporter protein (LysE YggA)
KU053_RS16880	COG1560	Kdo2-lipid A biosynthetic process
KU053_RS16890	COG1301	dicarboxylic acid transport
KU053_RS16945	COG0473	3-isopropylmalate dehydrogenase activity
KU053_RS17010	COG0583	DNA-binding transcription factor activity
KU053_RS17020	COG0625	glutathione transferase activity
KU053_RS17025	COG2378	regulation of single-species biofilm formation
KU053_RS17030	COG0546	phosphoglycolate phosphatase activity
KU053_RS17040	COG1530	ribonuclease E activity
KU053_RS17045	COG0318	PFAM AMP-dependent synthetase and ligase
KU053_RS17060	COG0583	DNA-binding transcription factor activity
KU053_RS17065	COG4221	oxidoreductase activity
KU053_RS17070	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KU053_RS17080	COG0534	Mate efflux family protein
KU053_RS17095	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KU053_RS17135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KU053_RS17140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU053_RS17155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU053_RS17165	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KU053_RS17165	COG0644	oxidoreductase
KU053_RS17170	COG0425	Belongs to the sulfur carrier protein TusA family
KU053_RS17175	COG4535	Mg2 and Co2 transporter CorC
KU053_RS17185	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU053_RS17205	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KU053_RS17210	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU053_RS17210	COG0475	glutathione-regulated potassium exporter activity
KU053_RS17215	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KU053_RS17225	COG0484	heat shock protein binding
KU053_RS17230	COG0789	Transcriptional regulator
KU053_RS17235	COG0598	Magnesium transport protein CorA
KU053_RS17250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU053_RS17255	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU053_RS17260	COG1074	ATP-dependent DNA helicase activity
KU053_RS17265	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KU053_RS17285	COG2226	methyltransferase
KU053_RS17300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU053_RS17305	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KU053_RS17320	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU053_RS17320	COG2111	Na H antiporter
KU053_RS17325	COG1006	Multisubunit Na H antiporter MnhC subunit
KU053_RS17330	COG0651	ATP synthesis coupled electron transport
KU053_RS17335	COG1863	multisubunit Na H antiporter MnhE subunit
KU053_RS17340	COG2212	antiporter activity
KU053_RS17345	COG1320	monovalent cation:proton antiporter activity
KU053_RS17360	COG0195	Participates in both transcription termination and antitermination
KU053_RS17410	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KU053_RS17415	COG0237	dephospho-CoA kinase activity
KU053_RS17425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU053_RS17440	COG0497	DNA recombination
KU053_RS17450	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KU053_RS17480	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU053_RS17480	COG2169	Transcriptional regulator
KU053_RS17485	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KU053_RS17550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KU053_RS17565	COG0326	Molecular chaperone. Has ATPase activity
KU053_RS17580	COG2056	Na+-H+ antiporter family
KU053_RS17585	COG0596	Alpha beta hydrolase
KU053_RS17680	COG0546	phosphoglycolate phosphatase activity
KU053_RS17685	COG1716	ATPase activity
KU053_RS17730	COG0181	hydroxymethylbilane synthase activity
KU053_RS17740	COG3275	phosphorelay sensor kinase activity
KU053_RS17760	COG1538	Outer membrane efflux protein
KU053_RS17765	COG0697	spore germination
KU053_RS17790	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU053_RS17795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KU053_RS17800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU053_RS17805	COG0772	Belongs to the SEDS family
KU053_RS17830	COG4974	Belongs to the 'phage' integrase family
KU053_RS17835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU053_RS17845	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KU053_RS17855	COG2197	response regulator
KU053_RS17870	COG0793	Belongs to the peptidase S41A family
KU053_RS17875	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KU053_RS17880	COG0795	lipopolysaccharide-transporting ATPase activity
KU053_RS17920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU053_RS17920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU053_RS17930	COG0004	ammonium transporteR
KU053_RS17935	COG0347	Belongs to the P(II) protein family
KU053_RS17995	COG0659	secondary active sulfate transmembrane transporter activity
KU053_RS18000	COG0589	response to stress
KU053_RS18045	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU053_RS18055	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU053_RS18075	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KU053_RS18090	COG0318	PFAM AMP-dependent synthetase and ligase
KU053_RS18100	COG0477	Major facilitator Superfamily
KU053_RS18105	COG2860	membrane
KU053_RS18115	COG1253	flavin adenine dinucleotide binding
KU053_RS18135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU053_RS18175	COG0655	NAD(P)H dehydrogenase (quinone) activity
KU053_RS18185	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KU053_RS18255	COG0758	DNA mediated transformation
KU053_RS18265	COG0697	spore germination
KU053_RS18270	COG1309	transcriptional regulator
KU053_RS18285	COG0386	Belongs to the glutathione peroxidase family
KU053_RS18350	COG1121	(ABC) transporter
KU053_RS18355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KU053_RS18360	COG1280	lysine exporter protein (LysE YggA)
KU053_RS18365	COG2837	iron assimilation
KU053_RS18375	COG0281	malic enzyme
KU053_RS18420	COG0519	Catalyzes the synthesis of GMP from XMP
KU053_RS18420	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU053_RS18425	COG4399	Belongs to the UPF0754 family
KU053_RS18430	COG2259	Doxx family
KU053_RS18435	COG0586	Pfam SNARE associated Golgi protein
KU053_RS18450	COG1192	Involved in chromosome partitioning
KU053_RS18460	COG0271	Belongs to the BolA IbaG family
KU053_RS18480	COG2267	carboxylic ester hydrolase activity
KU053_RS18500	COG3321	synthase
KU053_RS18500	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KU053_RS18500	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KU053_RS18500	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU053_RS18505	COG1960	acyl-CoA dehydrogenase activity
KU053_RS18515	COG2197	response regulator
KU053_RS18525	COG3916	Acyl-homoserine-lactone synthase
KU053_RS18530	COG0477	Major facilitator Superfamily
KU053_RS18535	COG1024	Enoyl-CoA hydratase
KU053_RS18540	COG1024	Enoyl-CoA hydratase
KU053_RS18545	COG1960	acyl-CoA dehydrogenase activity
KU053_RS18550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU053_RS18570	COG1113	amino acid transport
KU053_RS18575	COG1113	amino acid transport
KU053_RS18580	COG0251	oxidation-reduction process
KU053_RS18620	COG0564	pseudouridine synthase activity
KU053_RS18680	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KU053_RS18695	COG1802	Transcriptional regulator
KU053_RS18705	COG1448	Aminotransferase
KU053_RS18710	COG0277	FAD linked oxidase domain protein
KU053_RS18720	COG2186	Transcriptional regulator
KU053_RS18730	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU053_RS18740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU053_RS18755	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KU053_RS18760	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KU053_RS18780	COG1215	transferase activity, transferring glycosyl groups
KU053_RS18790	COG0438	transferase activity, transferring glycosyl groups
KU053_RS18815	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KU053_RS18820	COG1596	polysaccharide export
KU053_RS18845	COG0728	peptidoglycan biosynthetic process
KU053_RS18850	COG3023	N-Acetylmuramoyl-L-alanine amidase
KU053_RS18905	COG0546	phosphoglycolate phosphatase activity
KU053_RS18910	COG1028	Short-chain dehydrogenase reductase Sdr
KU053_RS18930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU053_RS18935	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU053_RS18940	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU053_RS18945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU053_RS18950	COG1116	anion transmembrane transporter activity
KU053_RS18955	COG1309	transcriptional regulator
KU053_RS18960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KU053_RS18970	COG0196	riboflavin kinase activity
KU053_RS18975	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KU053_RS18985	COG1047	Peptidyl-prolyl cis-trans
KU053_RS19025	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KU053_RS19030	COG0657	acetylesterase activity
KU053_RS19050	COG0583	DNA-binding transcription factor activity
KU053_RS19080	COG2951	lytic endotransglycosylase activity
KU053_RS19085	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KU053_RS19100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KU053_RS19110	COG0671	phosphoesterase, PA-phosphatase related
KU053_RS19115	COG0861	Integral membrane protein TerC family
KU053_RS19125	COG0754	glutathionylspermidine amidase activity
KU053_RS19135	COG0402	S-adenosylhomocysteine deaminase activity
KU053_RS19150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU053_RS19155	COG1230	cation diffusion facilitator family transporter
KU053_RS19170	COG0706	membrane insertase activity
KU053_RS19315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU053_RS19335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KU053_RS19415	COG1063	alcohol dehydrogenase
KU053_RS19440	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KU053_RS19455	COG1979	alcohol dehydrogenase
KU053_RS19465	COG1902	pentaerythritol trinitrate reductase activity
KU053_RS19475	COG1309	transcriptional regulator
KU053_RS19520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU053_RS19560	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU053_RS19565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU053_RS19565	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KU053_RS19615	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KU053_RS19615	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
KU053_RS19630	COG0587	DNA-directed DNA polymerase activity
KU053_RS19675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU053_RS19730	COG0358	DNA primase activity