locus-tag	class	description
KUY52_RS00010	COG0592	DNA-directed DNA polymerase activity
KUY52_RS00020	COG0187	DNA topoisomerase II activity
KUY52_RS00030	COG0586	Pfam SNARE associated Golgi protein
KUY52_RS00035	COG0488	(ABC) transporter
KUY52_RS00060	COG0596	Alpha beta hydrolase
KUY52_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KUY52_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KUY52_RS00110	COG0733	neurotransmitter:sodium symporter activity
KUY52_RS00150	COG2233	PERMEase
KUY52_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUY52_RS00200	COG2814	Major facilitator Superfamily
KUY52_RS00205	COG0656	L-ascorbic acid biosynthetic process
KUY52_RS00210	COG0583	DNA-binding transcription factor activity
KUY52_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUY52_RS00230	COG1064	alcohol dehydrogenase
KUY52_RS00235	COG2818	Glycosylase
KUY52_RS00250	COG1194	a g-specific adenine glycosylase
KUY52_RS00270	COG2983	Belongs to the UPF0260 family
KUY52_RS00275	COG2133	pyrroloquinoline quinone binding
KUY52_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KUY52_RS00285	COG2116	formate transmembrane transporter activity
KUY52_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUY52_RS00310	COG1335	isochorismatase
KUY52_RS00315	COG0385	Bile acid
KUY52_RS00320	COG0534	Mate efflux family protein
KUY52_RS00325	COG1683	Conserved Protein
KUY52_RS00345	COG0625	glutathione transferase activity
KUY52_RS00355	COG1113	amino acid transport
KUY52_RS00365	COG0523	cobalamin synthesis protein
KUY52_RS00375	COG2188	Transcriptional regulator
KUY52_RS00405	COG0010	Belongs to the arginase family
KUY52_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KUY52_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KUY52_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KUY52_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KUY52_RS00545	COG0534	Mate efflux family protein
KUY52_RS00550	COG0436	Aminotransferase
KUY52_RS00555	COG2733	membrane
KUY52_RS00570	COG2918	glutathione biosynthetic process
KUY52_RS00600	COG3150	esterase
KUY52_RS00610	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KUY52_RS00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUY52_RS00635	COG2233	PERMEase
KUY52_RS00640	COG2351	hydroxyisourate hydrolase activity
KUY52_RS00675	COG3706	GGDEF domain
KUY52_RS00690	COG1393	Belongs to the ArsC family
KUY52_RS00695	COG0708	Exodeoxyribonuclease III
KUY52_RS00715	COG0189	ligase activity
KUY52_RS00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KUY52_RS00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KUY52_RS00760	COG4942	peptidase
KUY52_RS00770	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUY52_RS00780	COG2119	membrane
KUY52_RS00785	COG4774	siderophore transport
KUY52_RS00790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KUY52_RS00790	COG0426	domain, Protein
KUY52_RS00815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KUY52_RS00835	COG1902	pentaerythritol trinitrate reductase activity
KUY52_RS00840	COG1519	Transferase
KUY52_RS00845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KUY52_RS00850	COG0668	transmembrane transport
KUY52_RS00860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KUY52_RS00865	COG1335	isochorismatase
KUY52_RS00870	COG1522	sequence-specific DNA binding
KUY52_RS00875	COG3328	transposase activity
KUY52_RS00900	COG0784	Response regulator, receiver
KUY52_RS00900	COG2198	Histidine kinase
KUY52_RS00900	COG2205	protein histidine kinase activity
KUY52_RS00905	COG3162	membrane
KUY52_RS00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUY52_RS00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KUY52_RS00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KUY52_RS00945	COG1309	transcriptional regulator
KUY52_RS00965	COG0352	thiamine-phosphate diphosphorylase activity
KUY52_RS00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KUY52_RS00965	COG0351	phosphomethylpyrimidine kinase
KUY52_RS00975	COG2814	Major facilitator Superfamily
KUY52_RS00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KUY52_RS01000	COG1113	amino acid transport
KUY52_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KUY52_RS01015	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS01025	COG1335	isochorismatase
KUY52_RS01075	COG2814	Major facilitator Superfamily
KUY52_RS01080	COG0583	DNA-binding transcription factor activity
KUY52_RS01105	COG0667	Aldo Keto reductase
KUY52_RS01140	COG1733	regulation of RNA biosynthetic process
KUY52_RS01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUY52_RS01210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KUY52_RS01225	COG2329	Antibiotic biosynthesis monooxygenase
KUY52_RS01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KUY52_RS01285	COG0427	acetyl-CoA hydrolase
KUY52_RS01310	COG0659	secondary active sulfate transmembrane transporter activity
KUY52_RS01315	COG4221	oxidoreductase activity
KUY52_RS01320	COG2873	o-acetylhomoserine
KUY52_RS01325	COG0488	(ABC) transporter
KUY52_RS01410	COG0833	amino acid
KUY52_RS01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KUY52_RS01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KUY52_RS01475	COG2226	methyltransferase
KUY52_RS01525	COG0070	glutamate synthase
KUY52_RS01525	COG0067	glutamate synthase
KUY52_RS01525	COG0069	glutamate synthase activity
KUY52_RS01530	COG0493	'glutamate synthase
KUY52_RS01540	COG1704	LemA family
KUY52_RS01545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KUY52_RS01555	COG4969	Belongs to the N-Me-Phe pilin family
KUY52_RS01560	COG3307	-O-antigen
KUY52_RS01580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KUY52_RS01595	COG0194	GDP metabolic process
KUY52_RS01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KUY52_RS01665	COG5380	lipid catabolic process
KUY52_RS01670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KUY52_RS01685	COG1061	Type III restriction enzyme res subunit
KUY52_RS01695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KUY52_RS01700	COG1192	Involved in chromosome partitioning
KUY52_RS01710	COG1061	Type III restriction enzyme res subunit
KUY52_RS01745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KUY52_RS01750	COG0277	FAD linked oxidase domain protein
KUY52_RS01760	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KUY52_RS01765	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUY52_RS01780	COG1289	transmembrane transporter activity
KUY52_RS01790	COG0628	permease
KUY52_RS01795	COG1192	Involved in chromosome partitioning
KUY52_RS01825	COG0833	amino acid
KUY52_RS01830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KUY52_RS01835	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KUY52_RS01845	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS01885	COG0583	DNA-binding transcription factor activity
KUY52_RS01930	COG0517	IMP dehydrogenase activity
KUY52_RS01935	COG1983	PspC domain protein
KUY52_RS01945	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS01960	COG0408	coproporphyrinogen oxidase activity
KUY52_RS01980	COG0513	Belongs to the DEAD box helicase family
KUY52_RS01990	COG1127	ABC transporter
KUY52_RS01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KUY52_RS02005	COG2854	intermembrane phospholipid transfer
KUY52_RS02015	COG0598	Magnesium transport protein CorA
KUY52_RS02025	COG0494	nUDIX hydrolase
KUY52_RS02030	COG1040	competence protein
KUY52_RS02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KUY52_RS02055	COG1946	Acyl-CoA thioesterase
KUY52_RS02060	COG1301	dicarboxylic acid transport
KUY52_RS02075	COG1959	2 iron, 2 sulfur cluster binding
KUY52_RS02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KUY52_RS02080	COG1017	nitric oxide dioxygenase activity
KUY52_RS02085	COG0433	COG0433 Predicted ATPase
KUY52_RS02090	COG0626	cystathionine gamma-synthase activity
KUY52_RS02245	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS02250	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KUY52_RS02280	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KUY52_RS02285	COG0339	signal peptide processing
KUY52_RS02290	COG0557	exoribonuclease II activity
KUY52_RS02335	COG0179	Fumarylacetoacetate (FAA) hydrolase
KUY52_RS02340	COG2169	Transcriptional regulator
KUY52_RS02345	COG0697	spore germination
KUY52_RS02350	COG1295	ribonuclease BN
KUY52_RS02385	COG1702	phosphate starvation-inducible protein PhoH
KUY52_RS02395	COG1196	nuclear chromosome segregation
KUY52_RS02395	COG0741	lytic transglycosylase activity
KUY52_RS02395	COG0739	heme binding
KUY52_RS02425	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KUY52_RS02430	COG1183	phosphatidylcholine synthase activity
KUY52_RS02475	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS02480	COG1309	transcriptional regulator
KUY52_RS02495	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUY52_RS02500	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS02520	COG2969	positive regulation of protein catabolic process
KUY52_RS02530	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KUY52_RS02545	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KUY52_RS02550	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KUY52_RS02570	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KUY52_RS02580	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KUY52_RS02585	COG1408	metallophosphoesterase
KUY52_RS02595	COG2199	diguanylate cyclase activity
KUY52_RS02655	COG1607	acyl-coa hydrolase
KUY52_RS02685	COG2350	Protein conserved in bacteria
KUY52_RS02695	COG0613	PHP domain protein
KUY52_RS02700	COG3781	membrane
KUY52_RS02710	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KUY52_RS02715	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KUY52_RS02725	COG1862	Preprotein translocase
KUY52_RS02775	COG2205	protein histidine kinase activity
KUY52_RS02780	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KUY52_RS02800	COG0726	polysaccharide deacetylase
KUY52_RS02805	COG0463	Glycosyl transferase, family 2
KUY52_RS02810	COG0438	transferase activity, transferring glycosyl groups
KUY52_RS02885	COG0625	glutathione transferase activity
KUY52_RS02890	COG0583	DNA-binding transcription factor activity
KUY52_RS02895	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS02900	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS02910	COG2205	protein histidine kinase activity
KUY52_RS02915	COG0745	RESPONSE REGULATOR receiver
KUY52_RS02920	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KUY52_RS02940	COG2096	Adenosyltransferase
KUY52_RS02990	COG0285	dihydrofolate synthase activity
KUY52_RS03010	COG0450	alkyl hydroperoxide reductase
KUY52_RS03025	COG0477	Major facilitator Superfamily
KUY52_RS03030	COG1272	protein, Hemolysin III
KUY52_RS03060	COG0183	Belongs to the thiolase family
KUY52_RS03065	COG2207	Transcriptional regulator
KUY52_RS03085	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUY52_RS03105	COG0183	Belongs to the thiolase family
KUY52_RS03115	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KUY52_RS03115	COG2885	chlorophyll binding
KUY52_RS03125	COG1690	Belongs to the RtcB family
KUY52_RS03130	COG0833	amino acid
KUY52_RS03140	COG2233	PERMEase
KUY52_RS03145	COG1217	gtp-binding protein TYPA
KUY52_RS03170	COG2094	Belongs to the DNA glycosylase MPG family
KUY52_RS03175	COG4772	TonB-dependent receptor
KUY52_RS03180	COG1902	pentaerythritol trinitrate reductase activity
KUY52_RS03195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KUY52_RS03200	COG0354	folic acid binding
KUY52_RS03210	COG3189	MarR family transcriptional regulator
KUY52_RS03215	COG2824	Alkylphosphonate utilization operon protein PhnA
KUY52_RS03220	COG3422	double-strand break repair
KUY52_RS03260	COG0840	transmembrane signaling receptor activity
KUY52_RS03280	COG5510	response to toxic substance
KUY52_RS03290	COG2832	Protein of unknown function (DUF454)
KUY52_RS03295	COG1376	ErfK ybiS ycfS ynhG family protein
KUY52_RS03335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KUY52_RS03345	COG1289	transmembrane transporter activity
KUY52_RS03350	COG2814	Major facilitator Superfamily
KUY52_RS03370	COG1115	amino acid carrier protein
KUY52_RS03375	COG1752	Esterase of the alpha-beta hydrolase superfamily
KUY52_RS03380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KUY52_RS03385	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KUY52_RS03415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KUY52_RS03425	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KUY52_RS03430	COG1077	Cell shape determining protein MreB Mrl
KUY52_RS03435	COG1792	Involved in formation and maintenance of cell shape
KUY52_RS03440	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KUY52_RS03445	COG0424	maF-like protein
KUY52_RS03450	COG1530	ribonuclease E activity
KUY52_RS03460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KUY52_RS03470	COG0560	Phosphoserine phosphatase
KUY52_RS03480	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUY52_RS03505	COG2207	Transcriptional regulator
KUY52_RS03525	COG1113	amino acid transport
KUY52_RS03530	COG2828	Protein conserved in bacteria
KUY52_RS03535	COG0142	geranyltranstransferase activity
KUY52_RS03540	COG2315	Protein conserved in bacteria
KUY52_RS03555	COG1752	Esterase of the alpha-beta hydrolase superfamily
KUY52_RS03580	COG2194	sulfuric ester hydrolase activity
KUY52_RS03585	COG0745	RESPONSE REGULATOR receiver
KUY52_RS03590	COG0642	Histidine kinase
KUY52_RS03600	COG0004	ammonium transporteR
KUY52_RS03605	COG0583	DNA-binding transcription factor activity
KUY52_RS03625	COG0525	valine-tRNA ligase activity
KUY52_RS03635	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS03645	COG0393	Putative heavy-metal-binding
KUY52_RS03650	COG0393	Putative heavy-metal-binding
KUY52_RS03655	COG1538	Outer membrane efflux protein
KUY52_RS03665	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUY52_RS03670	COG0671	phosphoesterase, PA-phosphatase related
KUY52_RS03700	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KUY52_RS03715	COG1648	precorrin-2 dehydrogenase activity
KUY52_RS03715	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KUY52_RS03720	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KUY52_RS03725	COG1733	regulation of RNA biosynthetic process
KUY52_RS03735	COG0531	amino acid
KUY52_RS03750	COG0321	lipoyl(octanoyl) transferase activity
KUY52_RS03755	COG2921	Belongs to the UPF0250 family
KUY52_RS03795	COG2009	succinate dehydrogenase
KUY52_RS03800	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KUY52_RS03805	COG1053	succinate dehydrogenase
KUY52_RS03810	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KUY52_RS03835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUY52_RS03855	COG2354	Protein conserved in bacteria
KUY52_RS03860	COG2321	neutral zinc metallopeptidase
KUY52_RS03880	COG2843	Capsule synthesis protein
KUY52_RS03895	COG0589	response to stress
KUY52_RS03915	COG0505	Belongs to the CarA family
KUY52_RS03940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KUY52_RS03945	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KUY52_RS03995	COG0477	Major facilitator Superfamily
KUY52_RS04000	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KUY52_RS04015	COG1597	lipid kinase activity
KUY52_RS04020	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KUY52_RS04045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUY52_RS04050	COG0584	glycerophosphoryl diester phosphodiesterase
KUY52_RS04070	COG0741	lytic transglycosylase activity
KUY52_RS04090	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KUY52_RS04105	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KUY52_RS04135	COG0778	Nitroreductase
KUY52_RS04150	COG1929	Belongs to the glycerate kinase type-1 family
KUY52_RS04155	COG0243	molybdopterin cofactor binding
KUY52_RS04160	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KUY52_RS04165	COG3339	Conserved Protein
KUY52_RS04175	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KUY52_RS04190	COG1113	amino acid transport
KUY52_RS04200	COG0019	diaminopimelate decarboxylase activity
KUY52_RS04210	COG1280	lysine exporter protein (LysE YggA)
KUY52_RS04215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KUY52_RS04245	COG0463	Glycosyl transferase, family 2
KUY52_RS04265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUY52_RS04300	COG4591	ABC-type transport system involved in lipoprotein release permease component
KUY52_RS04305	COG1136	(ABC) transporter
KUY52_RS04310	COG2333	competence protein COMEC
KUY52_RS04310	COG0658	competence protein
KUY52_RS04320	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KUY52_RS04320	COG0616	signal peptide processing
KUY52_RS04325	COG0596	Alpha beta hydrolase
KUY52_RS04330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KUY52_RS04340	COG0628	permease
KUY52_RS04375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUY52_RS04395	COG0823	Involved in the tonB-independent uptake of proteins
KUY52_RS04415	COG0824	Thioesterase
KUY52_RS04420	COG1473	amidohydrolase
KUY52_RS04440	COG0047	phosphoribosylformylglycinamidine synthase activity
KUY52_RS04440	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KUY52_RS04445	COG2814	Major facilitator Superfamily
KUY52_RS04455	COG1024	Enoyl-CoA hydratase
KUY52_RS04460	COG1056	cytidyltransferase-related domain
KUY52_RS04460	COG1051	belongs to the nudix hydrolase family
KUY52_RS04470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KUY52_RS04485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KUY52_RS04500	COG4625	pathogenesis
KUY52_RS04505	COG0583	DNA-binding transcription factor activity
KUY52_RS04510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KUY52_RS04515	COG4208	sulfate ABC transporter
KUY52_RS04520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KUY52_RS04530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KUY52_RS04535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KUY52_RS04540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KUY52_RS04560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KUY52_RS04575	COG0681	Belongs to the peptidase S26 family
KUY52_RS04590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KUY52_RS04600	COG1381	Involved in DNA repair and RecF pathway recombination
KUY52_RS04605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KUY52_RS04615	COG4221	oxidoreductase activity
KUY52_RS04645	COG0436	Aminotransferase
KUY52_RS04665	COG0556	nucleotide-excision repair
KUY52_RS04720	COG2070	2-Nitropropane dioxygenase
KUY52_RS04750	COG1215	transferase activity, transferring glycosyl groups
KUY52_RS04765	COG0415	Belongs to the DNA photolyase family
KUY52_RS04775	COG1252	NADH dehydrogenase
KUY52_RS04780	COG1686	Belongs to the peptidase S11 family
KUY52_RS04795	COG1187	pseudouridine synthase activity
KUY52_RS04820	COG0477	Major facilitator Superfamily
KUY52_RS04825	COG0583	DNA-binding transcription factor activity
KUY52_RS04830	COG1823	symporter activity
KUY52_RS04840	COG0612	Peptidase, M16
KUY52_RS04865	COG0352	thiamine-phosphate diphosphorylase activity
KUY52_RS04900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KUY52_RS04915	COG1309	transcriptional regulator
KUY52_RS04925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KUY52_RS04930	COG0076	glutamate decarboxylase activity
KUY52_RS04940	COG1522	sequence-specific DNA binding
KUY52_RS04945	COG3961	Belongs to the TPP enzyme family
KUY52_RS04950	COG1113	amino acid transport
KUY52_RS04955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KUY52_RS04960	COG0573	inorganic phosphate transmembrane transporter activity
KUY52_RS04970	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KUY52_RS04975	COG0616	signal peptide processing
KUY52_RS05010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KUY52_RS05015	COG1686	Belongs to the peptidase S11 family
KUY52_RS05040	COG0583	DNA-binding transcription factor activity
KUY52_RS05045	COG1067	ATP-dependent peptidase activity
KUY52_RS05090	COG1966	Carbon starvation protein
KUY52_RS05095	COG2879	small protein
KUY52_RS05130	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KUY52_RS05130	COG2508	Transcriptional regulator
KUY52_RS05150	COG1113	amino acid transport
KUY52_RS05155	COG0583	DNA-binding transcription factor activity
KUY52_RS05160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KUY52_RS05165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KUY52_RS05175	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS05185	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUY52_RS05190	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KUY52_RS05190	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KUY52_RS05225	COG2814	Major facilitator Superfamily
KUY52_RS05230	COG4948	Mandelate Racemase Muconate Lactonizing
KUY52_RS05240	COG1309	transcriptional regulator
KUY52_RS05260	COG1741	Belongs to the pirin family
KUY52_RS05270	COG2964	Protein conserved in bacteria
KUY52_RS05285	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KUY52_RS05290	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KUY52_RS05295	COG4605	iron ion homeostasis
KUY52_RS05300	COG4604	ABC transporter, ATP-binding protein
KUY52_RS05305	COG4607	ABC-type enterochelin transport system periplasmic component
KUY52_RS05310	COG4774	siderophore transport
KUY52_RS05320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KUY52_RS05325	COG1021	2,3-dihydroxybenzoate-AMP ligase
KUY52_RS05330	COG1535	isochorismatase
KUY52_RS05330	COG3433	isochorismatase activity
KUY52_RS05345	COG1132	(ABC) transporter
KUY52_RS05350	COG1132	(ABC) transporter
KUY52_RS05355	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KUY52_RS05365	COG1169	isochorismate synthase
KUY52_RS05380	COG3739	integral membrane protein
KUY52_RS05400	COG0302	gtp cyclohydrolase
KUY52_RS05410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KUY52_RS05440	COG0308	aminopeptidase N
KUY52_RS05445	COG0512	Glutamine amidotransferase of anthranilate synthase
KUY52_RS05460	COG0174	glutamine synthetase
KUY52_RS05470	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KUY52_RS05505	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KUY52_RS05510	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KUY52_RS05515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KUY52_RS05535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KUY52_RS05540	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KUY52_RS05545	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KUY52_RS05560	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS05565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KUY52_RS05570	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUY52_RS05580	COG2223	nitrite transmembrane transporter activity
KUY52_RS05590	COG0024	Methionine aminopeptidase
KUY52_RS05595	COG0052	Belongs to the universal ribosomal protein uS2 family
KUY52_RS05610	COG2207	Transcriptional regulator
KUY52_RS05635	COG2951	lytic endotransglycosylase activity
KUY52_RS05640	COG0772	Belongs to the SEDS family
KUY52_RS05655	COG0842	Transport permease protein
KUY52_RS05660	COG1131	(ABC) transporter
KUY52_RS05705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUY52_RS05730	COG4215	(ABC) transporter
KUY52_RS05735	COG4160	amino acid transport
KUY52_RS05740	COG4598	ABC transporter
KUY52_RS05750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KUY52_RS05755	COG0826	peptidase U32
KUY52_RS05760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUY52_RS05775	COG1720	tRNA m6t6A37 methyltransferase activity
KUY52_RS05785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KUY52_RS05800	COG0642	Histidine kinase
KUY52_RS05810	COG0494	nUDIX hydrolase
KUY52_RS05820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KUY52_RS05825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KUY52_RS05830	COG3139	Protein of unknown function (DUF1315)
KUY52_RS05835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KUY52_RS05840	COG1301	dicarboxylic acid transport
KUY52_RS05845	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS05850	COG2819	hydrolase of the alpha beta superfamily
KUY52_RS05860	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KUY52_RS05870	COG2195	Cleaves the N-terminal amino acid of tripeptides
KUY52_RS05875	COG1234	tRNA 3'-trailer cleavage
KUY52_RS05905	COG2363	Small membrane protein
KUY52_RS05930	COG0513	Belongs to the DEAD box helicase family
KUY52_RS05940	COG0778	Nitroreductase
KUY52_RS05970	COG1286	toxin biosynthetic process
KUY52_RS05995	COG4783	chaperone-mediated protein folding
KUY52_RS06000	COG1610	YqeY-like protein
KUY52_RS06100	COG3111	PFAM Bacterial OB fold (BOF) protein
KUY52_RS06125	COG3243	poly(R)-hydroxyalkanoic acid synthase
KUY52_RS06130	COG0786	glutamate:sodium symporter activity
KUY52_RS06140	COG2186	Transcriptional regulator
KUY52_RS06190	COG0477	Major facilitator Superfamily
KUY52_RS06220	COG2985	domain, Protein
KUY52_RS06230	COG2995	paraquat-inducible protein a
KUY52_RS06235	COG3008	intermembrane lipid transfer
KUY52_RS06235	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KUY52_RS06245	COG1794	racemase activity, acting on amino acids and derivatives
KUY52_RS06275	COG1301	dicarboxylic acid transport
KUY52_RS06285	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUY52_RS06290	COG2011	ABC-type metal ion transport system permease component
KUY52_RS06295	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KUY52_RS06300	COG1464	Belongs to the NlpA lipoprotein family
KUY52_RS06305	COG0151	Belongs to the GarS family
KUY52_RS06310	COG0138	bifunctional purine biosynthesis protein purh
KUY52_RS06315	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KUY52_RS06345	COG2308	Evidence 4 Homologs of previously reported genes of
KUY52_RS06355	COG1305	Transglutaminase-like
KUY52_RS06365	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KUY52_RS06370	COG0305	Participates in initiation and elongation during chromosome replication
KUY52_RS06395	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KUY52_RS06405	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KUY52_RS06410	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KUY52_RS06435	COG1649	PFAM Uncharacterised BCR, COG1649
KUY52_RS06435	COG0726	polysaccharide deacetylase
KUY52_RS06440	COG1215	transferase activity, transferring glycosyl groups
KUY52_RS06445	COG3658	cytochrome
KUY52_RS06455	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KUY52_RS06470	COG0583	DNA-binding transcription factor activity
KUY52_RS06490	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KUY52_RS06495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KUY52_RS06510	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS06515	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KUY52_RS06520	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KUY52_RS06545	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KUY52_RS06550	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KUY52_RS06560	COG2205	protein histidine kinase activity
KUY52_RS06565	COG0745	RESPONSE REGULATOR receiver
KUY52_RS06570	COG0174	glutamine synthetase
KUY52_RS06590	COG0729	surface antigen
KUY52_RS06615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KUY52_RS06620	COG2814	Major facilitator Superfamily
KUY52_RS06635	COG0583	DNA-binding transcription factor activity
KUY52_RS06650	COG1187	pseudouridine synthase activity
KUY52_RS06670	COG0802	atpase or kinase
KUY52_RS06675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KUY52_RS06685	COG1923	regulation of RNA biosynthetic process
KUY52_RS06690	COG0697	spore germination
KUY52_RS06705	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KUY52_RS06715	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KUY52_RS06720	COG0519	Catalyzes the synthesis of GMP from XMP
KUY52_RS06720	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KUY52_RS06725	COG4302	ethanolamine ammonia-lyase activity
KUY52_RS06730	COG4303	Ethanolamine ammonia lyase large subunit
KUY52_RS06735	COG0531	amino acid
KUY52_RS06755	COG1454	alcohol dehydrogenase
KUY52_RS06760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KUY52_RS06770	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KUY52_RS06790	COG0308	aminopeptidase N
KUY52_RS06800	COG4221	oxidoreductase activity
KUY52_RS06810	COG1605	Chorismate mutase
KUY52_RS06830	COG1309	transcriptional regulator
KUY52_RS06840	COG0668	transmembrane transport
KUY52_RS06875	COG4773	Receptor
KUY52_RS06895	COG0488	(ABC) transporter
KUY52_RS06900	COG0589	response to stress
KUY52_RS06925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KUY52_RS06935	COG3135	benzoate transporter
KUY52_RS06940	COG1522	sequence-specific DNA binding
KUY52_RS06950	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KUY52_RS06955	COG0583	DNA-binding transcription factor activity
KUY52_RS06965	COG0183	Belongs to the thiolase family
KUY52_RS06975	COG2030	dehydratase
KUY52_RS06980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KUY52_RS06995	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KUY52_RS07005	COG0824	Thioesterase
KUY52_RS07010	COG1454	alcohol dehydrogenase
KUY52_RS07020	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KUY52_RS07040	COG0069	glutamate synthase activity
KUY52_RS07225	COG5410	chromosome segregation
KUY52_RS07330	COG1598	PFAM Uncharacterised protein family UPF0150
KUY52_RS07420	COG2814	Major facilitator Superfamily
KUY52_RS07435	COG0511	ligase activity, forming carbon-carbon bonds
KUY52_RS07455	COG1116	anion transmembrane transporter activity
KUY52_RS07455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KUY52_RS07460	COG0745	RESPONSE REGULATOR receiver
KUY52_RS07470	COG2146	nitrite reductase [NAD(P)H] activity
KUY52_RS07470	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUY52_RS07475	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUY52_RS07480	COG0243	molybdopterin cofactor binding
KUY52_RS07490	COG0243	molybdopterin cofactor binding
KUY52_RS07495	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KUY52_RS07510	COG0315	cyclic pyranopterin monophosphate synthase activity
KUY52_RS07510	COG0521	Mo-molybdopterin cofactor biosynthetic process
KUY52_RS07515	COG0303	'Molybdopterin
KUY52_RS07525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUY52_RS07530	COG0697	spore germination
KUY52_RS07550	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KUY52_RS07555	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KUY52_RS07615	COG2135	peptidase activity
KUY52_RS07630	COG5001	Diguanylate cyclase
KUY52_RS07630	COG3300	MHYT domain
KUY52_RS07650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KUY52_RS07650	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KUY52_RS07650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KUY52_RS07655	COG1105	Belongs to the carbohydrate kinase PfkB family
KUY52_RS07660	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KUY52_RS07660	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KUY52_RS07690	COG0024	Methionine aminopeptidase
KUY52_RS07695	COG0583	DNA-binding transcription factor activity
KUY52_RS07705	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KUY52_RS07710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KUY52_RS07715	COG0516	GMP reductase activity
KUY52_RS07715	COG0517	IMP dehydrogenase activity
KUY52_RS07740	COG0552	protein localization to endoplasmic reticulum
KUY52_RS07750	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KUY52_RS07765	COG4890	Cyd operon protein YbgT
KUY52_RS07770	COG1294	oxidase, subunit
KUY52_RS07785	COG1585	Membrane protein implicated in regulation of membrane protease activity
KUY52_RS07795	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KUY52_RS07800	COG4774	siderophore transport
KUY52_RS07815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KUY52_RS07820	COG0569	domain protein
KUY52_RS07825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KUY52_RS07855	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KUY52_RS07860	COG0542	response to heat
KUY52_RS07885	COG1902	pentaerythritol trinitrate reductase activity
KUY52_RS07885	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUY52_RS07930	COG2323	membrane
KUY52_RS07935	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KUY52_RS07945	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KUY52_RS07950	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KUY52_RS07955	COG0183	Belongs to the thiolase family
KUY52_RS07960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KUY52_RS07965	COG0596	Alpha beta hydrolase
KUY52_RS07970	COG2271	Major facilitator Superfamily
KUY52_RS07975	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KUY52_RS07980	COG3485	protocatechuate 3,4-dioxygenase
KUY52_RS07985	COG3485	protocatechuate 3,4-dioxygenase
KUY52_RS07990	COG0710	3-dehydroquinate dehydratase activity
KUY52_RS07995	COG3420	alginic acid biosynthetic process
KUY52_RS08000	COG3659	wide pore channel activity
KUY52_RS08005	COG4993	Dehydrogenase
KUY52_RS08015	COG2391	methyltransferase activity
KUY52_RS08030	COG1414	Transcriptional regulator
KUY52_RS08035	COG0583	DNA-binding transcription factor activity
KUY52_RS08040	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS08065	COG2814	Major facilitator Superfamily
KUY52_RS08075	COG0154	amidase activity
KUY52_RS08095	COG4638	Rieske (2fe-2S)
KUY52_RS08105	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS08115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KUY52_RS08125	COG3733	amine oxidase
KUY52_RS08135	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS08145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KUY52_RS08150	COG0183	Belongs to the thiolase family
KUY52_RS08155	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KUY52_RS08160	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KUY52_RS08170	COG4829	muconolactone delta-isomerase
KUY52_RS08175	COG4948	Mandelate Racemase Muconate Lactonizing
KUY52_RS08180	COG0583	DNA-binding transcription factor activity
KUY52_RS08190	COG2186	Transcriptional regulator
KUY52_RS08210	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS08230	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS08235	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS08240	COG3829	transcription factor binding
KUY52_RS08250	COG3162	membrane
KUY52_RS08265	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS08280	COG0753	catalase activity
KUY52_RS08300	COG1846	Transcriptional regulator
KUY52_RS08305	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUY52_RS08305	COG1902	pentaerythritol trinitrate reductase activity
KUY52_RS08315	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KUY52_RS08345	COG1309	transcriptional regulator
KUY52_RS08355	COG1335	isochorismatase
KUY52_RS08360	COG0583	DNA-binding transcription factor activity
KUY52_RS08370	COG0475	glutathione-regulated potassium exporter activity
KUY52_RS08370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KUY52_RS08380	COG1473	amidohydrolase
KUY52_RS08390	COG2831	hemolysin activation secretion protein
KUY52_RS08395	COG3210	domain, Protein
KUY52_RS08425	COG2188	Transcriptional regulator
KUY52_RS08440	COG0583	DNA-binding transcription factor activity
KUY52_RS08470	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KUY52_RS08500	COG1566	PFAM secretion protein HlyD family protein
KUY52_RS08515	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS08520	COG0129	dihydroxy-acid dehydratase activity
KUY52_RS08530	COG0583	DNA-binding transcription factor activity
KUY52_RS08535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KUY52_RS08545	COG2084	Dehydrogenase
KUY52_RS08550	COG2207	Transcriptional regulator
KUY52_RS08565	COG1064	alcohol dehydrogenase
KUY52_RS08575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KUY52_RS08580	COG1120	ATPase activity
KUY52_RS08600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KUY52_RS08720	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KUY52_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS08785	COG2207	Transcriptional regulator
KUY52_RS08795	COG2205	protein histidine kinase activity
KUY52_RS08800	COG0745	RESPONSE REGULATOR receiver
KUY52_RS08805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUY52_RS08810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUY52_RS08815	COG1538	Outer membrane efflux protein
KUY52_RS08825	COG2072	flavoprotein involved in K transport
KUY52_RS08845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KUY52_RS08865	COG3539	Fimbrial protein
KUY52_RS08895	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KUY52_RS08905	COG0753	catalase activity
KUY52_RS08920	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KUY52_RS08980	COG3433	isochorismatase activity
KUY52_RS08980	COG1535	isochorismatase
KUY52_RS08985	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS08990	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KUY52_RS08995	COG4149	molybdate abc transporter
KUY52_RS09000	COG0725	ABC transporter, periplasmic molybdate-binding protein
KUY52_RS09010	COG4638	Rieske (2fe-2S)
KUY52_RS09015	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KUY52_RS09020	COG0543	2 iron, 2 sulfur cluster binding
KUY52_RS09020	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KUY52_RS09045	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS09060	COG2207	Transcriptional regulator
KUY52_RS09070	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS09085	COG0583	DNA-binding transcription factor activity
KUY52_RS09095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KUY52_RS09100	COG2031	fatty acid transporter
KUY52_RS09105	COG0183	Belongs to the thiolase family
KUY52_RS09110	COG0583	DNA-binding transcription factor activity
KUY52_RS09115	COG0583	DNA-binding transcription factor activity
KUY52_RS09130	COG1027	Aspartate ammonia-lyase
KUY52_RS09140	COG0477	Major facilitator Superfamily
KUY52_RS09160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KUY52_RS09165	COG4521	taurine ABC transporter
KUY52_RS09180	COG2188	Transcriptional regulator
KUY52_RS09190	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KUY52_RS09195	COG1733	regulation of RNA biosynthetic process
KUY52_RS09200	COG2207	Transcriptional regulator
KUY52_RS09200	COG3708	Transcriptional regulator
KUY52_RS09215	COG0730	response to heat
KUY52_RS09230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUY52_RS09230	COG3453	Protein conserved in bacteria
KUY52_RS09240	COG3781	membrane
KUY52_RS09245	COG1063	alcohol dehydrogenase
KUY52_RS09255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KUY52_RS09260	COG0508	dehydrogenase complex catalyzes the overall conversion of
KUY52_RS09265	COG0022	dehydrogenase e1 component
KUY52_RS09270	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KUY52_RS09275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KUY52_RS09290	COG3706	GGDEF domain
KUY52_RS09305	COG0133	tryptophan synthase activity
KUY52_RS09315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KUY52_RS09350	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KUY52_RS09375	COG2226	methyltransferase
KUY52_RS09435	COG0842	Transport permease protein
KUY52_RS09440	COG0842	Transport permease protein
KUY52_RS09445	COG1131	(ABC) transporter
KUY52_RS09460	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KUY52_RS09465	COG4773	Receptor
KUY52_RS09485	COG0730	response to heat
KUY52_RS09490	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KUY52_RS09510	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KUY52_RS09525	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KUY52_RS09565	COG4264	IucA IucC family
KUY52_RS09570	COG4264	IucA IucC family
KUY52_RS09590	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KUY52_RS09605	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS09610	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS09615	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KUY52_RS09620	COG2207	Transcriptional regulator
KUY52_RS09625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUY52_RS09630	COG0776	regulation of translation
KUY52_RS09655	COG0822	iron-sulfur transferase activity
KUY52_RS09660	COG0316	Belongs to the HesB IscA family
KUY52_RS09690	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KUY52_RS09710	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KUY52_RS09715	COG0702	epimerase
KUY52_RS09750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KUY52_RS09760	COG0339	signal peptide processing
KUY52_RS09810	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KUY52_RS09815	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KUY52_RS09845	COG0776	regulation of translation
KUY52_RS09910	COG0084	hydrolase, TatD family'
KUY52_RS09930	COG1663	tetraacyldisaccharide 4'-kinase activity
KUY52_RS09935	COG1132	(ABC) transporter
KUY52_RS09945	COG0811	peptide transport
KUY52_RS09950	COG1475	DNA binding
KUY52_RS09955	COG1192	Involved in chromosome partitioning
KUY52_RS09965	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KUY52_RS09980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KUY52_RS09985	COG0191	fructose-bisphosphate aldolase activity
KUY52_RS10005	COG0424	maF-like protein
KUY52_RS10010	COG2850	peptidyl-arginine hydroxylation
KUY52_RS10020	COG0640	Transcriptional regulator
KUY52_RS10030	COG3619	membrane
KUY52_RS10035	COG3122	Protein conserved in bacteria
KUY52_RS10040	COG1132	(ABC) transporter
KUY52_RS10060	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KUY52_RS10065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KUY52_RS10075	COG0506	proline dehydrogenase activity
KUY52_RS10075	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KUY52_RS10075	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KUY52_RS10080	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KUY52_RS10095	COG3698	Phosphodiester glycosidase
KUY52_RS10105	COG2353	YceI-like domain
KUY52_RS10115	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KUY52_RS10160	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KUY52_RS10160	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KUY52_RS10185	COG3539	Fimbrial protein
KUY52_RS10190	COG3121	Chaperone
KUY52_RS10215	COG0697	spore germination
KUY52_RS10225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KUY52_RS10235	COG0583	DNA-binding transcription factor activity
KUY52_RS10265	COG1309	transcriptional regulator
KUY52_RS10280	COG1522	sequence-specific DNA binding
KUY52_RS10290	COG1126	abc transporter atp-binding protein
KUY52_RS10295	COG0765	amino acid transport
KUY52_RS10300	COG0765	amino acid transport
KUY52_RS10330	COG1464	Belongs to the NlpA lipoprotein family
KUY52_RS10340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KUY52_RS10345	COG2011	ABC-type metal ion transport system permease component
KUY52_RS10350	COG0012	GTP binding
KUY52_RS10375	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KUY52_RS10415	COG0386	Belongs to the glutathione peroxidase family
KUY52_RS10425	COG0436	Aminotransferase
KUY52_RS10465	COG3634	alkyl hydroperoxide reductase activity
KUY52_RS10480	COG0583	DNA-binding transcription factor activity
KUY52_RS10485	COG0798	PFAM Bile acid sodium symporter
KUY52_RS10490	COG0640	Transcriptional regulator
KUY52_RS10505	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KUY52_RS10525	COG0659	secondary active sulfate transmembrane transporter activity
KUY52_RS10545	COG1113	amino acid transport
KUY52_RS10555	COG1522	sequence-specific DNA binding
KUY52_RS10580	COG1011	Hydrolase
KUY52_RS10585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KUY52_RS10595	COG2137	regulation of response to DNA damage stimulus
KUY52_RS10610	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KUY52_RS10645	COG0575	Belongs to the CDS family
KUY52_RS10650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KUY52_RS10670	COG3852	Histidine kinase
KUY52_RS10675	COG2204	response regulator
KUY52_RS10725	COG0477	Major facilitator Superfamily
KUY52_RS10745	COG1271	oxidase subunit
KUY52_RS10750	COG1294	oxidase, subunit
KUY52_RS10760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUY52_RS10780	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KUY52_RS10800	COG3052	prosthetic group binding
KUY52_RS10805	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KUY52_RS10815	COG2814	Major facilitator Superfamily
KUY52_RS10835	COG1346	cytolysis
KUY52_RS10845	COG0583	DNA-binding transcription factor activity
KUY52_RS10850	COG0625	glutathione transferase activity
KUY52_RS10855	COG0625	glutathione transferase activity
KUY52_RS10860	COG0583	DNA-binding transcription factor activity
KUY52_RS10875	COG1045	serine acetyltransferase
KUY52_RS10880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KUY52_RS10885	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KUY52_RS10895	COG1280	lysine exporter protein (LysE YggA)
KUY52_RS10910	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUY52_RS10915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUY52_RS10920	COG1126	abc transporter atp-binding protein
KUY52_RS10925	COG0765	amino acid transport
KUY52_RS10930	COG0765	amino acid transport
KUY52_RS10950	COG0784	Response regulator, receiver
KUY52_RS10950	COG2205	protein histidine kinase activity
KUY52_RS10970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KUY52_RS10990	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS11040	COG0583	DNA-binding transcription factor activity
KUY52_RS11060	COG0318	PFAM AMP-dependent synthetase and ligase
KUY52_RS11065	COG1309	transcriptional regulator
KUY52_RS11070	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS11075	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KUY52_RS11080	COG1024	Enoyl-CoA hydratase
KUY52_RS11085	COG4770	biotin carboxylase activity
KUY52_RS11095	COG0583	DNA-binding transcription factor activity
KUY52_RS11110	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS11120	COG2814	Major facilitator Superfamily
KUY52_RS11130	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KUY52_RS11135	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KUY52_RS11140	COG2814	Major facilitator Superfamily
KUY52_RS11145	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS11150	COG1024	Enoyl-CoA hydratase
KUY52_RS11155	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS11160	COG1250	3-hydroxyacyl-CoA dehydrogenase
KUY52_RS11165	COG0183	Belongs to the thiolase family
KUY52_RS11175	COG2814	Major facilitator Superfamily
KUY52_RS11185	COG1024	Enoyl-CoA hydratase
KUY52_RS11200	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS11205	COG2814	Major facilitator Superfamily
KUY52_RS11210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KUY52_RS11215	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KUY52_RS11230	COG3842	ATPase activity
KUY52_RS11235	COG1840	ABC-type Fe3 transport system, periplasmic component
KUY52_RS11245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUY52_RS11250	COG1414	Transcriptional regulator
KUY52_RS11260	COG0583	DNA-binding transcription factor activity
KUY52_RS11265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KUY52_RS11270	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS11280	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KUY52_RS11290	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS11295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KUY52_RS11300	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KUY52_RS11305	COG2267	carboxylic ester hydrolase activity
KUY52_RS11325	COG3038	cytochrome b561
KUY52_RS11330	COG0753	catalase activity
KUY52_RS11365	COG2050	protein possibly involved in aromatic compounds catabolism
KUY52_RS11375	COG3327	negative regulation of DNA-templated transcription, initiation
KUY52_RS11380	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KUY52_RS11385	COG0183	Belongs to the thiolase family
KUY52_RS11390	COG1250	3-hydroxyacyl-CoA dehydrogenase
KUY52_RS11395	COG1024	Enoyl-CoA hydratase
KUY52_RS11400	COG1024	Enoyl-CoA hydratase
KUY52_RS11405	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KUY52_RS11410	COG2151	metal-sulfur cluster biosynthetic enzyme
KUY52_RS11415	COG3396	Phenylacetate-CoA oxygenase
KUY52_RS11420	COG3460	Phenylacetate-CoA oxygenase
KUY52_RS11425	COG3396	Phenylacetate-CoA oxygenase
KUY52_RS11430	COG2030	dehydratase
KUY52_RS11430	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS11435	COG1760	l-serine dehydratase
KUY52_RS11440	COG0531	amino acid
KUY52_RS11445	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS11460	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUY52_RS11470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KUY52_RS11490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUY52_RS11500	COG0789	Transcriptional regulator
KUY52_RS11515	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KUY52_RS11530	COG2807	transmembrane transport
KUY52_RS11535	COG0590	tRNA wobble adenosine to inosine editing
KUY52_RS11655	COG1116	anion transmembrane transporter activity
KUY52_RS11660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KUY52_RS11670	COG0864	Transcriptional regulator
KUY52_RS11690	COG2249	NAD(P)H dehydrogenase (quinone) activity
KUY52_RS11695	COG0439	Biotin carboxylase
KUY52_RS11710	COG1063	alcohol dehydrogenase
KUY52_RS11720	COG1309	transcriptional regulator
KUY52_RS11740	COG0038	chloride channel
KUY52_RS11745	COG4770	biotin carboxylase activity
KUY52_RS11765	COG1914	H( )-stimulated, divalent metal cation uptake system
KUY52_RS11770	COG0583	DNA-binding transcription factor activity
KUY52_RS11820	COG1250	3-hydroxyacyl-CoA dehydrogenase
KUY52_RS11840	COG2814	Major facilitator Superfamily
KUY52_RS11855	COG1560	Kdo2-lipid A biosynthetic process
KUY52_RS11865	COG5006	permease, DMT superfamily
KUY52_RS11870	COG1522	sequence-specific DNA binding
KUY52_RS11885	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KUY52_RS11895	COG4122	O-methyltransferase activity
KUY52_RS11925	COG1538	Outer membrane efflux protein
KUY52_RS11930	COG1137	ATPase activity
KUY52_RS11935	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KUY52_RS11945	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KUY52_RS11950	COG0517	IMP dehydrogenase activity
KUY52_RS11950	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KUY52_RS11985	COG2814	Major facilitator Superfamily
KUY52_RS12020	COG1278	Cold shock
KUY52_RS12025	COG1280	lysine exporter protein (LysE YggA)
KUY52_RS12055	COG1570	exodeoxyribonuclease VII activity
KUY52_RS12140	COG2871	sodium ion transport
KUY52_RS12150	COG0583	DNA-binding transcription factor activity
KUY52_RS12160	COG4638	Rieske (2fe-2S)
KUY52_RS12170	COG0543	2 iron, 2 sulfur cluster binding
KUY52_RS12170	COG0633	Ferredoxin
KUY52_RS12175	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS12180	COG3135	benzoate transporter
KUY52_RS12185	COG2814	Major facilitator Superfamily
KUY52_RS12200	COG1643	Atp-dependent helicase
KUY52_RS12205	COG0450	alkyl hydroperoxide reductase
KUY52_RS12215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KUY52_RS12225	COG3634	alkyl hydroperoxide reductase activity
KUY52_RS12245	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KUY52_RS12250	COG0625	glutathione transferase activity
KUY52_RS12260	COG2885	chlorophyll binding
KUY52_RS12295	COG0542	response to heat
KUY52_RS12310	COG1765	OsmC-like protein
KUY52_RS12325	COG0667	Aldo Keto reductase
KUY52_RS12340	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KUY52_RS12350	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KUY52_RS12360	COG0527	aspartate kinase activity
KUY52_RS12370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KUY52_RS12380	COG3038	cytochrome b561
KUY52_RS12385	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KUY52_RS12390	COG2252	PERMEase
KUY52_RS12400	COG2072	flavoprotein involved in K transport
KUY52_RS12440	COG0531	amino acid
KUY52_RS12450	COG1113	amino acid transport
KUY52_RS12490	COG3209	COG3209 Rhs family protein
KUY52_RS12520	COG4269	membrane
KUY52_RS12535	COG1902	pentaerythritol trinitrate reductase activity
KUY52_RS12535	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUY52_RS12545	COG2203	Gaf domain
KUY52_RS12545	COG3706	GGDEF domain
KUY52_RS12545	COG4251	negative regulation of phosphorylation
KUY52_RS12545	COG5001	Diguanylate cyclase
KUY52_RS12555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KUY52_RS12575	COG4172	Belongs to the ABC transporter superfamily
KUY52_RS12580	COG4239	(ABC) transporter, permease
KUY52_RS12585	COG4174	ABC transporter (Permease)
KUY52_RS12595	COG1388	LysM domain
KUY52_RS12595	COG0741	lytic transglycosylase activity
KUY52_RS12595	COG0741	lytic transglycosylase activity
KUY52_RS12595	COG1388	LysM domain
KUY52_RS12600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KUY52_RS12640	COG0583	DNA-binding transcription factor activity
KUY52_RS12645	COG1279	arginine transmembrane transporter activity
KUY52_RS12665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUY52_RS12670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUY52_RS12675	COG0006	proline dipeptidase activity
KUY52_RS12715	COG2194	sulfuric ester hydrolase activity
KUY52_RS13090	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KUY52_RS13115	COG3384	dioxygenase
KUY52_RS13125	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KUY52_RS13130	COG2878	Part of a membrane complex involved in electron transport
KUY52_RS13135	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KUY52_RS13160	COG0768	penicillin binding
KUY52_RS13165	COG0742	ribosomal rna small subunit methyltransferase
KUY52_RS13180	COG0830	nickel cation binding
KUY52_RS13190	COG0804	urea catabolic process
KUY52_RS13235	COG1253	flavin adenine dinucleotide binding
KUY52_RS13290	COG1773	rubredoxin
KUY52_RS13295	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KUY52_RS13305	COG0583	DNA-binding transcription factor activity
KUY52_RS13340	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KUY52_RS13345	COG4181	ATPase activity
KUY52_RS13390	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KUY52_RS13410	COG0306	phosphate transporter
KUY52_RS13420	COG3958	Transketolase
KUY52_RS13425	COG3959	Transketolase, thiamine diphosphate binding domain
KUY52_RS13430	COG2271	Major facilitator Superfamily
KUY52_RS13435	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS13440	COG0583	DNA-binding transcription factor activity
KUY52_RS13455	COG2223	nitrite transmembrane transporter activity
KUY52_RS13460	COG2207	Transcriptional regulator
KUY52_RS13465	COG2066	Belongs to the glutaminase family
KUY52_RS13470	COG0242	peptide deformylase activity
KUY52_RS13475	COG0477	Major facilitator Superfamily
KUY52_RS13485	COG0028	Belongs to the TPP enzyme family
KUY52_RS13500	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS13505	COG2267	carboxylic ester hydrolase activity
KUY52_RS13515	COG2271	Major facilitator Superfamily
KUY52_RS13520	COG0446	pyridine nucleotide-disulphide oxidoreductase
KUY52_RS13530	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS13550	COG1414	Transcriptional regulator
KUY52_RS13565	COG1024	Enoyl-CoA hydratase
KUY52_RS13575	COG1215	transferase activity, transferring glycosyl groups
KUY52_RS13580	COG0726	polysaccharide deacetylase
KUY52_RS13580	COG1649	PFAM Uncharacterised BCR, COG1649
KUY52_RS13590	COG4681	YaeQ
KUY52_RS13600	COG0523	cobalamin synthesis protein
KUY52_RS13610	COG1607	acyl-coa hydrolase
KUY52_RS13620	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KUY52_RS13625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KUY52_RS13630	COG1309	transcriptional regulator
KUY52_RS13655	COG2040	homocysteine
KUY52_RS13660	COG0531	amino acid
KUY52_RS13685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUY52_RS13690	COG0477	Major facilitator Superfamily
KUY52_RS13750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KUY52_RS13835	COG0592	DNA-directed DNA polymerase activity
KUY52_RS13875	COG2026	Addiction module toxin, RelE StbE family
KUY52_RS14025	COG3755	Protein conserved in bacteria
KUY52_RS14070	COG1484	DNA-dependent DNA replication
KUY52_RS14185	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KUY52_RS14220	COG0405	Gamma-glutamyltransferase
KUY52_RS14225	COG2814	Major facilitator Superfamily
KUY52_RS14235	COG2050	protein possibly involved in aromatic compounds catabolism
KUY52_RS14250	COG1090	epimerase
KUY52_RS14270	COG0420	3'-5' exonuclease activity
KUY52_RS14295	COG0735	belongs to the Fur family
KUY52_RS14300	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KUY52_RS14320	COG0121	glutamine amidotransferase
KUY52_RS14335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KUY52_RS14345	COG0210	DNA helicase
KUY52_RS14350	COG2885	chlorophyll binding
KUY52_RS14355	COG0204	Acyl-transferase
KUY52_RS14370	COG2894	cell division
KUY52_RS14395	COG1280	lysine exporter protein (LysE YggA)
KUY52_RS14400	COG1674	ftsk spoiiie
KUY52_RS14400	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KUY52_RS14405	COG0492	ferredoxin-NADP+ reductase activity
KUY52_RS14410	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KUY52_RS14420	COG0456	acetyltransferase
KUY52_RS14465	COG1981	membrane
KUY52_RS14480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KUY52_RS14480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUY52_RS14500	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS14510	COG0657	acetylesterase activity
KUY52_RS14520	COG0473	3-isopropylmalate dehydrogenase activity
KUY52_RS14525	COG0583	DNA-binding transcription factor activity
KUY52_RS14545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KUY52_RS14570	COG0564	pseudouridine synthase activity
KUY52_RS14580	COG0358	DNA primase activity
KUY52_RS14595	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KUY52_RS14625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KUY52_RS14655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KUY52_RS14665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KUY52_RS14665	COG0352	thiamine-phosphate diphosphorylase activity
KUY52_RS14665	COG0351	phosphomethylpyrimidine kinase
KUY52_RS14670	COG1652	LysM domain
KUY52_RS14695	COG1399	metal-binding, possibly nucleic acid-binding protein
KUY52_RS14700	COG3101	peptidyl-lysine hydroxylation
KUY52_RS14705	COG0009	L-threonylcarbamoyladenylate synthase
KUY52_RS14710	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KUY52_RS14715	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KUY52_RS14730	COG4106	trans-aconitate 2-methyltransferase activity
KUY52_RS14745	COG0596	Alpha beta hydrolase
KUY52_RS14745	COG2226	methyltransferase
KUY52_RS14745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KUY52_RS14750	COG1877	trehalose-phosphatase activity
KUY52_RS14755	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KUY52_RS14760	COG2223	nitrite transmembrane transporter activity
KUY52_RS14780	COG1196	nuclear chromosome segregation
KUY52_RS14790	COG0730	response to heat
KUY52_RS14805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KUY52_RS14815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUY52_RS14865	COG0489	protein tyrosine kinase activity
KUY52_RS14875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUY52_RS14875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUY52_RS14905	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KUY52_RS14910	COG2081	HI0933 family
KUY52_RS14920	COG0668	transmembrane transport
KUY52_RS14940	COG0583	DNA-binding transcription factor activity
KUY52_RS14960	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KUY52_RS14965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KUY52_RS14995	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KUY52_RS15035	COG0745	RESPONSE REGULATOR receiver
KUY52_RS15055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KUY52_RS15065	COG2205	protein histidine kinase activity
KUY52_RS15135	COG4993	Dehydrogenase
KUY52_RS15160	COG0384	phenazine biosynthesis protein PhzF
KUY52_RS15185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KUY52_RS15200	COG0583	DNA-binding transcription factor activity
KUY52_RS15230	COG0583	DNA-binding transcription factor activity
KUY52_RS15245	COG0583	DNA-binding transcription factor activity
KUY52_RS15250	COG1053	succinate dehydrogenase
KUY52_RS15260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KUY52_RS15265	COG2814	Major facilitator Superfamily
KUY52_RS15270	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS15275	COG0583	DNA-binding transcription factor activity
KUY52_RS15280	COG1063	alcohol dehydrogenase
KUY52_RS15310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KUY52_RS15315	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KUY52_RS15320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KUY52_RS15335	COG3667	copper resistance
KUY52_RS15340	COG2132	Multicopper oxidase
KUY52_RS15350	COG0561	phosphatase activity
KUY52_RS15355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KUY52_RS15380	COG1214	PFAM Peptidase M22, glycoprotease
KUY52_RS15430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KUY52_RS15440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KUY52_RS15445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KUY52_RS15450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KUY52_RS15510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KUY52_RS15520	COG1846	Transcriptional regulator
KUY52_RS15525	COG1764	response to oxidative stress
KUY52_RS15575	COG0037	tRNA processing
KUY52_RS15585	COG0248	Ppx GppA phosphatase
KUY52_RS15615	COG0072	phenylalanine-tRNA ligase activity
KUY52_RS15660	COG1238	metal cluster binding
KUY52_RS15665	COG0625	glutathione transferase activity
KUY52_RS15680	COG0318	PFAM AMP-dependent synthetase and ligase
KUY52_RS15685	COG3028	Belongs to the UPF0307 family
KUY52_RS15690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KUY52_RS15710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KUY52_RS15715	COG0617	tRNA 3'-terminal CCA addition
KUY52_RS15720	COG1555	photosystem II stabilization
KUY52_RS15725	COG3956	TIGRFAM MazG family protein
KUY52_RS15735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KUY52_RS15755	COG0784	Response regulator, receiver
KUY52_RS15755	COG5002	protein histidine kinase activity
KUY52_RS15755	COG2205	protein histidine kinase activity
KUY52_RS15760	COG1024	Enoyl-CoA hydratase
KUY52_RS15765	COG2084	Dehydrogenase
KUY52_RS15770	COG3622	Belongs to the hyi family
KUY52_RS15800	COG0697	spore germination
KUY52_RS15810	COG2814	Major facilitator Superfamily
KUY52_RS15815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KUY52_RS15825	COG0583	DNA-binding transcription factor activity
KUY52_RS15835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KUY52_RS15850	COG0084	hydrolase, TatD family'
KUY52_RS15865	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KUY52_RS15895	COG0440	acetolactate synthase activity
KUY52_RS15900	COG0028	Belongs to the TPP enzyme family
KUY52_RS15925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KUY52_RS15930	COG0577	efflux transmembrane transporter activity
KUY52_RS15930	COG1136	(ABC) transporter
KUY52_RS15935	COG1538	Outer membrane efflux protein
KUY52_RS15950	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KUY52_RS15955	COG1162	GTPase activity
KUY52_RS15965	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KUY52_RS15985	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KUY52_RS15990	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS16030	COG2986	histidine ammonia-lyase
KUY52_RS16045	COG0318	PFAM AMP-dependent synthetase and ligase
KUY52_RS16055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KUY52_RS16100	COG1426	Protein conserved in bacteria
KUY52_RS16135	COG0793	Belongs to the peptidase S41A family
KUY52_RS16150	COG2267	carboxylic ester hydrolase activity
KUY52_RS16160	COG1012	belongs to the aldehyde dehydrogenase family
KUY52_RS16165	COG3265	gluconokinase activity
KUY52_RS16175	COG0800	Aldolase
KUY52_RS16185	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KUY52_RS16190	COG0280	phosphate acetyltransferase
KUY52_RS16190	COG0857	belongs to the CobB CobQ family
KUY52_RS16195	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KUY52_RS16195	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KUY52_RS16215	COG0740	serine-type endopeptidase activity
KUY52_RS16225	COG4774	siderophore transport
KUY52_RS16235	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KUY52_RS16245	COG2813	Specifically methylates the guanine in position
KUY52_RS16245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KUY52_RS16345	COG0788	formyltetrahydrofolate deformylase activity
KUY52_RS16370	COG4651	solute:proton antiporter activity
KUY52_RS16370	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KUY52_RS16390	COG0724	RNA recognition motif
KUY52_RS16395	COG0210	DNA helicase
KUY52_RS16420	COG1733	regulation of RNA biosynthetic process
KUY52_RS16430	COG2900	Belongs to the SlyX family
KUY52_RS16435	COG0488	(ABC) transporter
KUY52_RS16440	COG1280	lysine exporter protein (LysE YggA)
KUY52_RS16445	COG1560	Kdo2-lipid A biosynthetic process
KUY52_RS16455	COG1301	dicarboxylic acid transport
KUY52_RS16510	COG0473	3-isopropylmalate dehydrogenase activity
KUY52_RS16575	COG0583	DNA-binding transcription factor activity
KUY52_RS16585	COG0625	glutathione transferase activity
KUY52_RS16590	COG2378	regulation of single-species biofilm formation
KUY52_RS16595	COG0546	phosphoglycolate phosphatase activity
KUY52_RS16605	COG1530	ribonuclease E activity
KUY52_RS16610	COG0318	PFAM AMP-dependent synthetase and ligase
KUY52_RS16625	COG0583	DNA-binding transcription factor activity
KUY52_RS16630	COG4221	oxidoreductase activity
KUY52_RS16635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KUY52_RS16645	COG0534	Mate efflux family protein
KUY52_RS16660	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KUY52_RS16700	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KUY52_RS16705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KUY52_RS16720	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KUY52_RS16730	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KUY52_RS16730	COG0644	oxidoreductase
KUY52_RS16735	COG0425	Belongs to the sulfur carrier protein TusA family
KUY52_RS16740	COG4535	Mg2 and Co2 transporter CorC
KUY52_RS16750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KUY52_RS16770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KUY52_RS16775	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KUY52_RS16775	COG0475	glutathione-regulated potassium exporter activity
KUY52_RS16780	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KUY52_RS16790	COG0484	heat shock protein binding
KUY52_RS16795	COG0789	Transcriptional regulator
KUY52_RS16800	COG0598	Magnesium transport protein CorA
KUY52_RS16815	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KUY52_RS16820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KUY52_RS16825	COG1074	ATP-dependent DNA helicase activity
KUY52_RS16830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KUY52_RS16850	COG2226	methyltransferase
KUY52_RS16865	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KUY52_RS16870	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KUY52_RS16885	COG2111	Na H antiporter
KUY52_RS16885	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KUY52_RS16890	COG1006	Multisubunit Na H antiporter MnhC subunit
KUY52_RS16895	COG0651	ATP synthesis coupled electron transport
KUY52_RS16900	COG1863	multisubunit Na H antiporter MnhE subunit
KUY52_RS16905	COG2212	antiporter activity
KUY52_RS16910	COG1320	monovalent cation:proton antiporter activity
KUY52_RS16925	COG0195	Participates in both transcription termination and antitermination
KUY52_RS16975	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KUY52_RS16980	COG0237	dephospho-CoA kinase activity
KUY52_RS16990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KUY52_RS17005	COG0497	DNA recombination
KUY52_RS17015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KUY52_RS17045	COG2169	Transcriptional regulator
KUY52_RS17045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KUY52_RS17050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KUY52_RS17115	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KUY52_RS17130	COG0326	Molecular chaperone. Has ATPase activity
KUY52_RS17145	COG2056	Na+-H+ antiporter family
KUY52_RS17150	COG0596	Alpha beta hydrolase
KUY52_RS17245	COG0546	phosphoglycolate phosphatase activity
KUY52_RS17250	COG1716	ATPase activity
KUY52_RS17295	COG0181	hydroxymethylbilane synthase activity
KUY52_RS17305	COG3275	phosphorelay sensor kinase activity
KUY52_RS17325	COG1538	Outer membrane efflux protein
KUY52_RS17330	COG0697	spore germination
KUY52_RS17355	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KUY52_RS17360	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KUY52_RS17365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KUY52_RS17370	COG0772	Belongs to the SEDS family
KUY52_RS17395	COG4974	Belongs to the 'phage' integrase family
KUY52_RS17400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KUY52_RS17410	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KUY52_RS17420	COG2197	response regulator
KUY52_RS17435	COG0793	Belongs to the peptidase S41A family
KUY52_RS17440	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KUY52_RS17445	COG0795	lipopolysaccharide-transporting ATPase activity
KUY52_RS17485	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KUY52_RS17485	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KUY52_RS17495	COG0004	ammonium transporteR
KUY52_RS17500	COG0347	Belongs to the P(II) protein family
KUY52_RS17560	COG0659	secondary active sulfate transmembrane transporter activity
KUY52_RS17565	COG0589	response to stress
KUY52_RS17600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KUY52_RS17610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KUY52_RS17630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KUY52_RS17645	COG0318	PFAM AMP-dependent synthetase and ligase
KUY52_RS17655	COG0477	Major facilitator Superfamily
KUY52_RS17660	COG2860	membrane
KUY52_RS17670	COG1253	flavin adenine dinucleotide binding
KUY52_RS17690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KUY52_RS17730	COG0655	NAD(P)H dehydrogenase (quinone) activity
KUY52_RS17740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KUY52_RS17810	COG0758	DNA mediated transformation
KUY52_RS17820	COG0697	spore germination
KUY52_RS17825	COG1309	transcriptional regulator
KUY52_RS17840	COG0386	Belongs to the glutathione peroxidase family
KUY52_RS17905	COG1121	(ABC) transporter
KUY52_RS17910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KUY52_RS17915	COG1280	lysine exporter protein (LysE YggA)
KUY52_RS17920	COG2837	iron assimilation
KUY52_RS17930	COG0281	malic enzyme
KUY52_RS17975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KUY52_RS17975	COG0519	Catalyzes the synthesis of GMP from XMP
KUY52_RS17980	COG4399	Belongs to the UPF0754 family
KUY52_RS17985	COG2259	Doxx family
KUY52_RS17990	COG0586	Pfam SNARE associated Golgi protein
KUY52_RS18005	COG1192	Involved in chromosome partitioning
KUY52_RS18015	COG0271	Belongs to the BolA IbaG family
KUY52_RS18035	COG2267	carboxylic ester hydrolase activity
KUY52_RS18055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KUY52_RS18055	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KUY52_RS18055	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KUY52_RS18055	COG3321	synthase
KUY52_RS18060	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS18070	COG2197	response regulator
KUY52_RS18080	COG3916	Acyl-homoserine-lactone synthase
KUY52_RS18085	COG0477	Major facilitator Superfamily
KUY52_RS18090	COG1024	Enoyl-CoA hydratase
KUY52_RS18095	COG1024	Enoyl-CoA hydratase
KUY52_RS18100	COG1960	acyl-CoA dehydrogenase activity
KUY52_RS18105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KUY52_RS18125	COG1113	amino acid transport
KUY52_RS18130	COG1113	amino acid transport
KUY52_RS18135	COG0251	oxidation-reduction process
KUY52_RS18175	COG0564	pseudouridine synthase activity
KUY52_RS18235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KUY52_RS18250	COG1802	Transcriptional regulator
KUY52_RS18260	COG1448	Aminotransferase
KUY52_RS18265	COG0277	FAD linked oxidase domain protein
KUY52_RS18275	COG2186	Transcriptional regulator
KUY52_RS18285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KUY52_RS18290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KUY52_RS18305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KUY52_RS18315	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KUY52_RS18325	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KUY52_RS18330	COG0438	transferase activity, transferring glycosyl groups
KUY52_RS18350	COG1216	Glycosyl transferase, family 2
KUY52_RS18355	COG5039	Polysaccharide pyruvyl transferase
KUY52_RS18365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KUY52_RS18370	COG1596	polysaccharide export
KUY52_RS18395	COG0728	peptidoglycan biosynthetic process
KUY52_RS18400	COG3023	N-Acetylmuramoyl-L-alanine amidase
KUY52_RS18455	COG0546	phosphoglycolate phosphatase activity
KUY52_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
KUY52_RS18480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KUY52_RS18485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KUY52_RS18490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KUY52_RS18495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KUY52_RS18500	COG1116	anion transmembrane transporter activity
KUY52_RS18505	COG1309	transcriptional regulator
KUY52_RS18510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KUY52_RS18520	COG0196	riboflavin kinase activity
KUY52_RS18525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KUY52_RS18535	COG1047	Peptidyl-prolyl cis-trans
KUY52_RS18575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KUY52_RS18580	COG0657	acetylesterase activity
KUY52_RS18600	COG0583	DNA-binding transcription factor activity
KUY52_RS18630	COG2951	lytic endotransglycosylase activity
KUY52_RS18635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KUY52_RS18650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KUY52_RS18660	COG0671	phosphoesterase, PA-phosphatase related
KUY52_RS18665	COG0861	Integral membrane protein TerC family
KUY52_RS18675	COG0754	glutathionylspermidine amidase activity
KUY52_RS18685	COG0402	S-adenosylhomocysteine deaminase activity
KUY52_RS18700	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KUY52_RS18705	COG1230	cation diffusion facilitator family transporter
KUY52_RS18720	COG0706	membrane insertase activity