locus-tag	class	description
KU058_RS00010	COG0592	DNA-directed DNA polymerase activity
KU058_RS00020	COG0187	DNA topoisomerase II activity
KU058_RS00030	COG0586	Pfam SNARE associated Golgi protein
KU058_RS00035	COG0488	(ABC) transporter
KU058_RS00060	COG0596	Alpha beta hydrolase
KU058_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KU058_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KU058_RS00110	COG0733	neurotransmitter:sodium symporter activity
KU058_RS00150	COG2233	PERMEase
KU058_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_RS00200	COG2814	Major facilitator Superfamily
KU058_RS00205	COG0656	L-ascorbic acid biosynthetic process
KU058_RS00210	COG0583	DNA-binding transcription factor activity
KU058_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_RS00230	COG1064	alcohol dehydrogenase
KU058_RS00235	COG2818	Glycosylase
KU058_RS00250	COG1194	a g-specific adenine glycosylase
KU058_RS00270	COG2983	Belongs to the UPF0260 family
KU058_RS00275	COG2133	pyrroloquinoline quinone binding
KU058_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KU058_RS00285	COG2116	formate transmembrane transporter activity
KU058_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU058_RS00310	COG1335	isochorismatase
KU058_RS00315	COG0385	Bile acid
KU058_RS00320	COG0534	Mate efflux family protein
KU058_RS00325	COG1683	Conserved Protein
KU058_RS00345	COG0625	glutathione transferase activity
KU058_RS00355	COG1113	amino acid transport
KU058_RS00365	COG0523	cobalamin synthesis protein
KU058_RS00375	COG2188	Transcriptional regulator
KU058_RS00405	COG0010	Belongs to the arginase family
KU058_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU058_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KU058_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KU058_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KU058_RS00540	COG0534	Mate efflux family protein
KU058_RS00545	COG0436	Aminotransferase
KU058_RS00550	COG2733	membrane
KU058_RS00565	COG2918	glutathione biosynthetic process
KU058_RS00580	COG1388	LysM domain
KU058_RS00580	COG0791	NLP P60 protein
KU058_RS00595	COG3150	esterase
KU058_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KU058_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_RS00630	COG2233	PERMEase
KU058_RS00635	COG2351	hydroxyisourate hydrolase activity
KU058_RS00670	COG3706	GGDEF domain
KU058_RS00685	COG1393	Belongs to the ArsC family
KU058_RS00690	COG0708	Exodeoxyribonuclease III
KU058_RS00710	COG0189	ligase activity
KU058_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KU058_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KU058_RS00755	COG4942	peptidase
KU058_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU058_RS00775	COG2119	membrane
KU058_RS00780	COG4774	siderophore transport
KU058_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_RS00785	COG0426	domain, Protein
KU058_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KU058_RS00830	COG1902	pentaerythritol trinitrate reductase activity
KU058_RS00835	COG1519	Transferase
KU058_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU058_RS00845	COG0668	transmembrane transport
KU058_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU058_RS00860	COG1335	isochorismatase
KU058_RS00865	COG1522	sequence-specific DNA binding
KU058_RS00870	COG3328	transposase activity
KU058_RS00895	COG0784	Response regulator, receiver
KU058_RS00895	COG2198	Histidine kinase
KU058_RS00895	COG2205	protein histidine kinase activity
KU058_RS00900	COG3162	membrane
KU058_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU058_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KU058_RS00940	COG1309	transcriptional regulator
KU058_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
KU058_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU058_RS00960	COG0351	phosphomethylpyrimidine kinase
KU058_RS00970	COG2814	Major facilitator Superfamily
KU058_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU058_RS00995	COG1113	amino acid transport
KU058_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU058_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS01020	COG1335	isochorismatase
KU058_RS01050	COG2814	Major facilitator Superfamily
KU058_RS01055	COG0583	DNA-binding transcription factor activity
KU058_RS01075	COG0667	Aldo Keto reductase
KU058_RS01110	COG1733	regulation of RNA biosynthetic process
KU058_RS01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU058_RS01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KU058_RS01195	COG2329	Antibiotic biosynthesis monooxygenase
KU058_RS01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KU058_RS01255	COG0427	acetyl-CoA hydrolase
KU058_RS01280	COG0659	secondary active sulfate transmembrane transporter activity
KU058_RS01285	COG4221	oxidoreductase activity
KU058_RS01290	COG2873	o-acetylhomoserine
KU058_RS01295	COG0488	(ABC) transporter
KU058_RS01380	COG0833	amino acid
KU058_RS01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KU058_RS01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KU058_RS01445	COG2226	methyltransferase
KU058_RS01495	COG0069	glutamate synthase activity
KU058_RS01495	COG0070	glutamate synthase
KU058_RS01495	COG0067	glutamate synthase
KU058_RS01500	COG0493	'glutamate synthase
KU058_RS01510	COG1704	LemA family
KU058_RS01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KU058_RS01535	COG3307	-O-antigen
KU058_RS01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU058_RS01575	COG0194	GDP metabolic process
KU058_RS01625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KU058_RS01645	COG5380	lipid catabolic process
KU058_RS01650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KU058_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KU058_RS01680	COG0277	FAD linked oxidase domain protein
KU058_RS01690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KU058_RS01695	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU058_RS01710	COG1289	transmembrane transporter activity
KU058_RS01720	COG0628	permease
KU058_RS01725	COG1192	Involved in chromosome partitioning
KU058_RS01755	COG0833	amino acid
KU058_RS01760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU058_RS01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU058_RS01775	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS01815	COG0583	DNA-binding transcription factor activity
KU058_RS01860	COG0517	IMP dehydrogenase activity
KU058_RS01865	COG1983	PspC domain protein
KU058_RS01875	COG1960	acyl-CoA dehydrogenase activity
KU058_RS01890	COG0408	coproporphyrinogen oxidase activity
KU058_RS01910	COG0513	Belongs to the DEAD box helicase family
KU058_RS01920	COG1127	ABC transporter
KU058_RS01925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KU058_RS01935	COG2854	intermembrane phospholipid transfer
KU058_RS01945	COG0598	Magnesium transport protein CorA
KU058_RS01955	COG0494	nUDIX hydrolase
KU058_RS01960	COG1040	competence protein
KU058_RS01965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KU058_RS01985	COG1946	Acyl-CoA thioesterase
KU058_RS01990	COG1301	dicarboxylic acid transport
KU058_RS02005	COG1959	2 iron, 2 sulfur cluster binding
KU058_RS02010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU058_RS02010	COG1017	nitric oxide dioxygenase activity
KU058_RS02015	COG0433	COG0433 Predicted ATPase
KU058_RS02020	COG0626	cystathionine gamma-synthase activity
KU058_RS02175	COG1960	acyl-CoA dehydrogenase activity
KU058_RS02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KU058_RS02210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KU058_RS02215	COG0339	signal peptide processing
KU058_RS02220	COG0557	exoribonuclease II activity
KU058_RS02265	COG0179	Fumarylacetoacetate (FAA) hydrolase
KU058_RS02270	COG2169	Transcriptional regulator
KU058_RS02275	COG0697	spore germination
KU058_RS02280	COG1295	ribonuclease BN
KU058_RS02315	COG1702	phosphate starvation-inducible protein PhoH
KU058_RS02325	COG0739	heme binding
KU058_RS02325	COG0741	lytic transglycosylase activity
KU058_RS02325	COG1196	nuclear chromosome segregation
KU058_RS02355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KU058_RS02360	COG1183	phosphatidylcholine synthase activity
KU058_RS02405	COG1960	acyl-CoA dehydrogenase activity
KU058_RS02410	COG1309	transcriptional regulator
KU058_RS02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU058_RS02430	COG1960	acyl-CoA dehydrogenase activity
KU058_RS02450	COG2969	positive regulation of protein catabolic process
KU058_RS02460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KU058_RS02475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KU058_RS02480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KU058_RS02500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KU058_RS02510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU058_RS02515	COG1408	metallophosphoesterase
KU058_RS02525	COG2199	diguanylate cyclase activity
KU058_RS02585	COG1607	acyl-coa hydrolase
KU058_RS02615	COG2350	Protein conserved in bacteria
KU058_RS02625	COG0613	PHP domain protein
KU058_RS02630	COG3781	membrane
KU058_RS02640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KU058_RS02645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KU058_RS02655	COG1862	Preprotein translocase
KU058_RS02685	COG2205	protein histidine kinase activity
KU058_RS02690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KU058_RS02710	COG0726	polysaccharide deacetylase
KU058_RS02715	COG0463	Glycosyl transferase, family 2
KU058_RS02720	COG0438	transferase activity, transferring glycosyl groups
KU058_RS02785	COG0625	glutathione transferase activity
KU058_RS02790	COG0583	DNA-binding transcription factor activity
KU058_RS02795	COG1960	acyl-CoA dehydrogenase activity
KU058_RS02800	COG1960	acyl-CoA dehydrogenase activity
KU058_RS02810	COG2205	protein histidine kinase activity
KU058_RS02815	COG0745	RESPONSE REGULATOR receiver
KU058_RS02820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KU058_RS02840	COG2096	Adenosyltransferase
KU058_RS02890	COG0285	dihydrofolate synthase activity
KU058_RS02910	COG0450	alkyl hydroperoxide reductase
KU058_RS02925	COG0477	Major facilitator Superfamily
KU058_RS02930	COG1272	protein, Hemolysin III
KU058_RS02960	COG0183	Belongs to the thiolase family
KU058_RS02965	COG2207	Transcriptional regulator
KU058_RS02985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_RS03005	COG0183	Belongs to the thiolase family
KU058_RS03015	COG2885	chlorophyll binding
KU058_RS03015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KU058_RS03025	COG1690	Belongs to the RtcB family
KU058_RS03030	COG0833	amino acid
KU058_RS03040	COG2233	PERMEase
KU058_RS03045	COG1217	gtp-binding protein TYPA
KU058_RS03070	COG2094	Belongs to the DNA glycosylase MPG family
KU058_RS03090	COG1902	pentaerythritol trinitrate reductase activity
KU058_RS03105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU058_RS03110	COG0354	folic acid binding
KU058_RS03120	COG3189	MarR family transcriptional regulator
KU058_RS03125	COG2824	Alkylphosphonate utilization operon protein PhnA
KU058_RS03130	COG3422	double-strand break repair
KU058_RS03170	COG0840	transmembrane signaling receptor activity
KU058_RS03190	COG5510	response to toxic substance
KU058_RS03200	COG2832	Protein of unknown function (DUF454)
KU058_RS03205	COG1376	ErfK ybiS ycfS ynhG family protein
KU058_RS03245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KU058_RS03255	COG1289	transmembrane transporter activity
KU058_RS03260	COG2814	Major facilitator Superfamily
KU058_RS03280	COG1115	amino acid carrier protein
KU058_RS03285	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU058_RS03290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU058_RS03295	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KU058_RS03325	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU058_RS03335	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KU058_RS03340	COG1077	Cell shape determining protein MreB Mrl
KU058_RS03345	COG1792	Involved in formation and maintenance of cell shape
KU058_RS03350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KU058_RS03355	COG0424	maF-like protein
KU058_RS03360	COG1530	ribonuclease E activity
KU058_RS03370	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU058_RS03380	COG0560	Phosphoserine phosphatase
KU058_RS03390	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU058_RS03415	COG2207	Transcriptional regulator
KU058_RS03435	COG1113	amino acid transport
KU058_RS03440	COG2828	Protein conserved in bacteria
KU058_RS03445	COG0142	geranyltranstransferase activity
KU058_RS03450	COG2315	Protein conserved in bacteria
KU058_RS03465	COG1752	Esterase of the alpha-beta hydrolase superfamily
KU058_RS03485	COG2194	sulfuric ester hydrolase activity
KU058_RS03490	COG0745	RESPONSE REGULATOR receiver
KU058_RS03495	COG0642	Histidine kinase
KU058_RS03505	COG0004	ammonium transporteR
KU058_RS03510	COG0583	DNA-binding transcription factor activity
KU058_RS03530	COG0525	valine-tRNA ligase activity
KU058_RS03540	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS03550	COG0393	Putative heavy-metal-binding
KU058_RS03555	COG0393	Putative heavy-metal-binding
KU058_RS03560	COG1538	Outer membrane efflux protein
KU058_RS03570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_RS03575	COG0671	phosphoesterase, PA-phosphatase related
KU058_RS03605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KU058_RS03620	COG1648	precorrin-2 dehydrogenase activity
KU058_RS03620	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KU058_RS03625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KU058_RS03630	COG1733	regulation of RNA biosynthetic process
KU058_RS03640	COG0531	amino acid
KU058_RS03655	COG0321	lipoyl(octanoyl) transferase activity
KU058_RS03660	COG2921	Belongs to the UPF0250 family
KU058_RS03700	COG2009	succinate dehydrogenase
KU058_RS03705	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KU058_RS03710	COG1053	succinate dehydrogenase
KU058_RS03715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KU058_RS03740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU058_RS03760	COG2354	Protein conserved in bacteria
KU058_RS03765	COG2321	neutral zinc metallopeptidase
KU058_RS03785	COG2843	Capsule synthesis protein
KU058_RS03800	COG0589	response to stress
KU058_RS03820	COG0505	Belongs to the CarA family
KU058_RS03845	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU058_RS03850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KU058_RS03900	COG0477	Major facilitator Superfamily
KU058_RS03905	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KU058_RS03920	COG1597	lipid kinase activity
KU058_RS03925	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU058_RS03955	COG0584	glycerophosphoryl diester phosphodiesterase
KU058_RS03975	COG0741	lytic transglycosylase activity
KU058_RS03995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KU058_RS04010	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU058_RS04040	COG0778	Nitroreductase
KU058_RS04055	COG1929	Belongs to the glycerate kinase type-1 family
KU058_RS04060	COG0243	molybdopterin cofactor binding
KU058_RS04065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KU058_RS04070	COG3339	Conserved Protein
KU058_RS04080	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KU058_RS04095	COG1113	amino acid transport
KU058_RS04105	COG0019	diaminopimelate decarboxylase activity
KU058_RS04115	COG1280	lysine exporter protein (LysE YggA)
KU058_RS04120	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU058_RS04150	COG0463	Glycosyl transferase, family 2
KU058_RS04170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_RS04205	COG4591	ABC-type transport system involved in lipoprotein release permease component
KU058_RS04210	COG1136	(ABC) transporter
KU058_RS04215	COG2333	competence protein COMEC
KU058_RS04215	COG0658	competence protein
KU058_RS04225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KU058_RS04225	COG0616	signal peptide processing
KU058_RS04230	COG0596	Alpha beta hydrolase
KU058_RS04235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KU058_RS04245	COG0628	permease
KU058_RS04280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU058_RS04300	COG0823	Involved in the tonB-independent uptake of proteins
KU058_RS04320	COG0824	Thioesterase
KU058_RS04325	COG1473	amidohydrolase
KU058_RS04345	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KU058_RS04345	COG0047	phosphoribosylformylglycinamidine synthase activity
KU058_RS04350	COG2814	Major facilitator Superfamily
KU058_RS04360	COG1024	Enoyl-CoA hydratase
KU058_RS04365	COG1051	belongs to the nudix hydrolase family
KU058_RS04365	COG1056	cytidyltransferase-related domain
KU058_RS04375	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KU058_RS04390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KU058_RS04405	COG4625	pathogenesis
KU058_RS04410	COG0583	DNA-binding transcription factor activity
KU058_RS04415	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KU058_RS04420	COG4208	sulfate ABC transporter
KU058_RS04425	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KU058_RS04435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KU058_RS04440	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KU058_RS04445	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KU058_RS04465	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU058_RS04480	COG0681	Belongs to the peptidase S26 family
KU058_RS04495	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KU058_RS04505	COG1381	Involved in DNA repair and RecF pathway recombination
KU058_RS04510	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KU058_RS04520	COG4221	oxidoreductase activity
KU058_RS04550	COG0436	Aminotransferase
KU058_RS04570	COG0556	nucleotide-excision repair
KU058_RS04625	COG2070	2-Nitropropane dioxygenase
KU058_RS04655	COG1215	transferase activity, transferring glycosyl groups
KU058_RS04670	COG0415	Belongs to the DNA photolyase family
KU058_RS04680	COG1252	NADH dehydrogenase
KU058_RS04685	COG1686	Belongs to the peptidase S11 family
KU058_RS04700	COG1187	pseudouridine synthase activity
KU058_RS04725	COG0477	Major facilitator Superfamily
KU058_RS04730	COG0583	DNA-binding transcription factor activity
KU058_RS04735	COG1823	symporter activity
KU058_RS04745	COG0612	Peptidase, M16
KU058_RS04770	COG0352	thiamine-phosphate diphosphorylase activity
KU058_RS04805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU058_RS04820	COG1309	transcriptional regulator
KU058_RS04830	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KU058_RS04835	COG0076	glutamate decarboxylase activity
KU058_RS04845	COG1522	sequence-specific DNA binding
KU058_RS04850	COG3961	Belongs to the TPP enzyme family
KU058_RS04855	COG1113	amino acid transport
KU058_RS04860	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU058_RS04865	COG0573	inorganic phosphate transmembrane transporter activity
KU058_RS04875	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KU058_RS04880	COG0616	signal peptide processing
KU058_RS04915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KU058_RS04920	COG1686	Belongs to the peptidase S11 family
KU058_RS04945	COG0583	DNA-binding transcription factor activity
KU058_RS04950	COG1067	ATP-dependent peptidase activity
KU058_RS04995	COG1966	Carbon starvation protein
KU058_RS05000	COG2879	small protein
KU058_RS05100	COG1802	Transcriptional regulator
KU058_RS05100	COG4626	Terminase
KU058_RS05105	COG4695	Portal protein
KU058_RS05225	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU058_RS05260	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
KU058_RS05260	COG2508	Transcriptional regulator
KU058_RS05280	COG1113	amino acid transport
KU058_RS05285	COG0583	DNA-binding transcription factor activity
KU058_RS05290	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_RS05295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_RS05305	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS05315	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_RS05320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU058_RS05320	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
KU058_RS05355	COG2814	Major facilitator Superfamily
KU058_RS05360	COG4948	Mandelate Racemase Muconate Lactonizing
KU058_RS05370	COG1309	transcriptional regulator
KU058_RS05390	COG1741	Belongs to the pirin family
KU058_RS05400	COG2964	Protein conserved in bacteria
KU058_RS05415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU058_RS05420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU058_RS05425	COG4605	iron ion homeostasis
KU058_RS05430	COG4604	ABC transporter, ATP-binding protein
KU058_RS05435	COG4607	ABC-type enterochelin transport system periplasmic component
KU058_RS05440	COG4774	siderophore transport
KU058_RS05450	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KU058_RS05455	COG1021	2,3-dihydroxybenzoate-AMP ligase
KU058_RS05460	COG1535	isochorismatase
KU058_RS05460	COG3433	isochorismatase activity
KU058_RS05475	COG1132	(ABC) transporter
KU058_RS05480	COG1132	(ABC) transporter
KU058_RS05485	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KU058_RS05495	COG1169	isochorismate synthase
KU058_RS05510	COG3739	integral membrane protein
KU058_RS05535	COG0302	gtp cyclohydrolase
KU058_RS05545	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KU058_RS05575	COG0308	aminopeptidase N
KU058_RS05580	COG0512	Glutamine amidotransferase of anthranilate synthase
KU058_RS05765	COG5410	chromosome segregation
KU058_RS05935	COG0582	viral genome integration into host DNA
KU058_RS05950	COG0174	glutamine synthetase
KU058_RS05960	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KU058_RS05995	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KU058_RS06000	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KU058_RS06005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KU058_RS06025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KU058_RS06030	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KU058_RS06035	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KU058_RS06050	COG1960	acyl-CoA dehydrogenase activity
KU058_RS06055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU058_RS06060	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU058_RS06070	COG2223	nitrite transmembrane transporter activity
KU058_RS06080	COG0024	Methionine aminopeptidase
KU058_RS06085	COG0052	Belongs to the universal ribosomal protein uS2 family
KU058_RS06100	COG2207	Transcriptional regulator
KU058_RS06125	COG2951	lytic endotransglycosylase activity
KU058_RS06130	COG0772	Belongs to the SEDS family
KU058_RS06145	COG0842	Transport permease protein
KU058_RS06150	COG1131	(ABC) transporter
KU058_RS06195	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_RS06210	COG4215	(ABC) transporter
KU058_RS06215	COG4160	amino acid transport
KU058_RS06220	COG4598	ABC transporter
KU058_RS06230	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU058_RS06235	COG0826	peptidase U32
KU058_RS06240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_RS06255	COG1720	tRNA m6t6A37 methyltransferase activity
KU058_RS06265	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KU058_RS06280	COG0642	Histidine kinase
KU058_RS06290	COG0494	nUDIX hydrolase
KU058_RS06300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KU058_RS06305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KU058_RS06310	COG3139	Protein of unknown function (DUF1315)
KU058_RS06315	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KU058_RS06320	COG1301	dicarboxylic acid transport
KU058_RS06325	COG1960	acyl-CoA dehydrogenase activity
KU058_RS06330	COG2819	hydrolase of the alpha beta superfamily
KU058_RS06340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KU058_RS06350	COG2195	Cleaves the N-terminal amino acid of tripeptides
KU058_RS06355	COG1234	tRNA 3'-trailer cleavage
KU058_RS06385	COG2363	Small membrane protein
KU058_RS06410	COG0513	Belongs to the DEAD box helicase family
KU058_RS06420	COG0778	Nitroreductase
KU058_RS06770	COG1286	toxin biosynthetic process
KU058_RS06795	COG4783	chaperone-mediated protein folding
KU058_RS06800	COG1610	YqeY-like protein
KU058_RS06900	COG3111	PFAM Bacterial OB fold (BOF) protein
KU058_RS06925	COG3243	poly(R)-hydroxyalkanoic acid synthase
KU058_RS06930	COG0786	glutamate:sodium symporter activity
KU058_RS06940	COG2186	Transcriptional regulator
KU058_RS06990	COG0477	Major facilitator Superfamily
KU058_RS07020	COG2985	domain, Protein
KU058_RS07030	COG2995	paraquat-inducible protein a
KU058_RS07035	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KU058_RS07035	COG3008	intermembrane lipid transfer
KU058_RS07060	COG1309	transcriptional regulator
KU058_RS07065	COG1741	Belongs to the pirin family
KU058_RS07080	COG2072	flavoprotein involved in K transport
KU058_RS07090	COG2252	PERMEase
KU058_RS07095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KU058_RS07100	COG3038	cytochrome b561
KU058_RS07110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KU058_RS07120	COG0527	aspartate kinase activity
KU058_RS07160	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU058_RS07245	COG1484	DNA-dependent DNA replication
KU058_RS07490	COG0592	DNA-directed DNA polymerase activity
KU058_RS07590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU058_RS07615	COG0582	viral genome integration into host DNA
KU058_RS07625	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KU058_RS07635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KU058_RS07650	COG0667	Aldo Keto reductase
KU058_RS07670	COG1765	OsmC-like protein
KU058_RS07685	COG0542	response to heat
KU058_RS07720	COG2885	chlorophyll binding
KU058_RS07730	COG0625	glutathione transferase activity
KU058_RS07735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KU058_RS07760	COG3634	alkyl hydroperoxide reductase activity
KU058_RS07770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KU058_RS07780	COG0450	alkyl hydroperoxide reductase
KU058_RS07785	COG1643	Atp-dependent helicase
KU058_RS07800	COG2814	Major facilitator Superfamily
KU058_RS07805	COG3135	benzoate transporter
KU058_RS07810	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS07815	COG0633	Ferredoxin
KU058_RS07815	COG0543	2 iron, 2 sulfur cluster binding
KU058_RS07820	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU058_RS07825	COG4638	Rieske (2fe-2S)
KU058_RS07835	COG0583	DNA-binding transcription factor activity
KU058_RS07885	COG1570	exodeoxyribonuclease VII activity
KU058_RS07915	COG1280	lysine exporter protein (LysE YggA)
KU058_RS07920	COG1278	Cold shock
KU058_RS07955	COG2814	Major facilitator Superfamily
KU058_RS07990	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KU058_RS07990	COG0517	IMP dehydrogenase activity
KU058_RS07995	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KU058_RS08005	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KU058_RS08010	COG1137	ATPase activity
KU058_RS08015	COG1538	Outer membrane efflux protein
KU058_RS08045	COG4122	O-methyltransferase activity
KU058_RS08055	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KU058_RS08070	COG1522	sequence-specific DNA binding
KU058_RS08075	COG5006	permease, DMT superfamily
KU058_RS08085	COG1560	Kdo2-lipid A biosynthetic process
KU058_RS08100	COG2814	Major facilitator Superfamily
KU058_RS08120	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU058_RS08170	COG0583	DNA-binding transcription factor activity
KU058_RS08175	COG1914	H( )-stimulated, divalent metal cation uptake system
KU058_RS08195	COG4770	biotin carboxylase activity
KU058_RS08200	COG0038	chloride channel
KU058_RS08220	COG1309	transcriptional regulator
KU058_RS08230	COG1063	alcohol dehydrogenase
KU058_RS08245	COG0439	Biotin carboxylase
KU058_RS08250	COG2249	NAD(P)H dehydrogenase (quinone) activity
KU058_RS08270	COG0864	Transcriptional regulator
KU058_RS08280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU058_RS08285	COG1116	anion transmembrane transporter activity
KU058_RS08405	COG0590	tRNA wobble adenosine to inosine editing
KU058_RS08410	COG2807	transmembrane transport
KU058_RS08425	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KU058_RS08440	COG0789	Transcriptional regulator
KU058_RS08450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU058_RS08470	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU058_RS08480	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_RS08495	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS08500	COG0531	amino acid
KU058_RS08505	COG1760	l-serine dehydratase
KU058_RS08510	COG2030	dehydratase
KU058_RS08510	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS08515	COG3396	Phenylacetate-CoA oxygenase
KU058_RS08520	COG3460	Phenylacetate-CoA oxygenase
KU058_RS08525	COG3396	Phenylacetate-CoA oxygenase
KU058_RS08530	COG2151	metal-sulfur cluster biosynthetic enzyme
KU058_RS08535	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU058_RS08540	COG1024	Enoyl-CoA hydratase
KU058_RS08545	COG1024	Enoyl-CoA hydratase
KU058_RS08550	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU058_RS08555	COG0183	Belongs to the thiolase family
KU058_RS08560	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KU058_RS08565	COG3327	negative regulation of DNA-templated transcription, initiation
KU058_RS08575	COG2050	protein possibly involved in aromatic compounds catabolism
KU058_RS08610	COG0753	catalase activity
KU058_RS08615	COG3038	cytochrome b561
KU058_RS08635	COG2267	carboxylic ester hydrolase activity
KU058_RS08640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_RS08645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU058_RS08650	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS08660	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU058_RS08670	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS08675	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU058_RS08680	COG0583	DNA-binding transcription factor activity
KU058_RS08690	COG1414	Transcriptional regulator
KU058_RS08695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_RS08705	COG1840	ABC-type Fe3 transport system, periplasmic component
KU058_RS08710	COG3842	ATPase activity
KU058_RS08735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KU058_RS08740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU058_RS08745	COG2814	Major facilitator Superfamily
KU058_RS08750	COG1960	acyl-CoA dehydrogenase activity
KU058_RS08765	COG1024	Enoyl-CoA hydratase
KU058_RS08775	COG2814	Major facilitator Superfamily
KU058_RS08785	COG0183	Belongs to the thiolase family
KU058_RS08790	COG1250	3-hydroxyacyl-CoA dehydrogenase
KU058_RS08795	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS08800	COG1024	Enoyl-CoA hydratase
KU058_RS08805	COG1960	acyl-CoA dehydrogenase activity
KU058_RS08810	COG2814	Major facilitator Superfamily
KU058_RS08815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU058_RS08820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU058_RS08830	COG2814	Major facilitator Superfamily
KU058_RS08840	COG1960	acyl-CoA dehydrogenase activity
KU058_RS08855	COG0583	DNA-binding transcription factor activity
KU058_RS08865	COG4770	biotin carboxylase activity
KU058_RS08870	COG1024	Enoyl-CoA hydratase
KU058_RS08875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KU058_RS08880	COG1960	acyl-CoA dehydrogenase activity
KU058_RS08885	COG1309	transcriptional regulator
KU058_RS08890	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_RS08915	COG0583	DNA-binding transcription factor activity
KU058_RS08965	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS08985	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU058_RS09005	COG2205	protein histidine kinase activity
KU058_RS09005	COG0784	Response regulator, receiver
KU058_RS09025	COG0765	amino acid transport
KU058_RS09030	COG0765	amino acid transport
KU058_RS09035	COG1126	abc transporter atp-binding protein
KU058_RS09040	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU058_RS09045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KU058_RS09060	COG1280	lysine exporter protein (LysE YggA)
KU058_RS09070	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KU058_RS09075	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU058_RS09080	COG1045	serine acetyltransferase
KU058_RS09095	COG0583	DNA-binding transcription factor activity
KU058_RS09100	COG0625	glutathione transferase activity
KU058_RS09105	COG0625	glutathione transferase activity
KU058_RS09110	COG0583	DNA-binding transcription factor activity
KU058_RS09120	COG1346	cytolysis
KU058_RS09140	COG2814	Major facilitator Superfamily
KU058_RS09150	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KU058_RS09155	COG3052	prosthetic group binding
KU058_RS09175	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KU058_RS09195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_RS09205	COG1294	oxidase, subunit
KU058_RS09210	COG1271	oxidase subunit
KU058_RS09230	COG0477	Major facilitator Superfamily
KU058_RS09240	COG4521	taurine ABC transporter
KU058_RS09245	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KU058_RS09250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU058_RS09255	COG2175	clavaminate synthase activity
KU058_RS09265	COG1953	Uracil, thiamine, allantoin
KU058_RS09275	COG0583	DNA-binding transcription factor activity
KU058_RS09285	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KU058_RS09300	COG0640	Transcriptional regulator
KU058_RS09305	COG0798	PFAM Bile acid sodium symporter
KU058_RS09310	COG0583	DNA-binding transcription factor activity
KU058_RS09325	COG3634	alkyl hydroperoxide reductase activity
KU058_RS09365	COG0436	Aminotransferase
KU058_RS09375	COG0386	Belongs to the glutathione peroxidase family
KU058_RS09415	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KU058_RS09440	COG0012	GTP binding
KU058_RS09445	COG2011	ABC-type metal ion transport system permease component
KU058_RS09450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU058_RS09460	COG1464	Belongs to the NlpA lipoprotein family
KU058_RS09490	COG0765	amino acid transport
KU058_RS09495	COG0765	amino acid transport
KU058_RS09500	COG1126	abc transporter atp-binding protein
KU058_RS09515	COG1522	sequence-specific DNA binding
KU058_RS09530	COG1309	transcriptional regulator
KU058_RS09550	COG0583	DNA-binding transcription factor activity
KU058_RS09560	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KU058_RS09570	COG0697	spore germination
KU058_RS09595	COG3121	Chaperone
KU058_RS09600	COG3539	Fimbrial protein
KU058_RS09625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KU058_RS09625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KU058_RS09670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KU058_RS09680	COG2353	YceI-like domain
KU058_RS09690	COG3698	Phosphodiester glycosidase
KU058_RS09705	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KU058_RS09710	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU058_RS09710	COG0506	proline dehydrogenase activity
KU058_RS09710	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KU058_RS09720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KU058_RS09725	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KU058_RS09745	COG1132	(ABC) transporter
KU058_RS09750	COG3122	Protein conserved in bacteria
KU058_RS09755	COG3619	membrane
KU058_RS09765	COG0640	Transcriptional regulator
KU058_RS09775	COG2850	peptidyl-arginine hydroxylation
KU058_RS09780	COG0424	maF-like protein
KU058_RS09800	COG0191	fructose-bisphosphate aldolase activity
KU058_RS09805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU058_RS09820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU058_RS09830	COG1192	Involved in chromosome partitioning
KU058_RS09835	COG1475	DNA binding
KU058_RS09840	COG0811	peptide transport
KU058_RS09850	COG1132	(ABC) transporter
KU058_RS09855	COG1663	tetraacyldisaccharide 4'-kinase activity
KU058_RS09875	COG0084	hydrolase, TatD family'
KU058_RS09940	COG0776	regulation of translation
KU058_RS09970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KU058_RS09975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KU058_RS10025	COG0339	signal peptide processing
KU058_RS10035	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KU058_RS10070	COG0702	epimerase
KU058_RS10075	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU058_RS10105	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KU058_RS10135	COG0316	Belongs to the HesB IscA family
KU058_RS10140	COG0822	iron-sulfur transferase activity
KU058_RS10165	COG0776	regulation of translation
KU058_RS10170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KU058_RS10175	COG2207	Transcriptional regulator
KU058_RS10180	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU058_RS10185	COG1960	acyl-CoA dehydrogenase activity
KU058_RS10190	COG1960	acyl-CoA dehydrogenase activity
KU058_RS10205	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KU058_RS10225	COG4264	IucA IucC family
KU058_RS10230	COG4264	IucA IucC family
KU058_RS10270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KU058_RS10285	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KU058_RS10305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KU058_RS10310	COG0730	response to heat
KU058_RS10330	COG4773	Receptor
KU058_RS10335	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU058_RS10350	COG1131	(ABC) transporter
KU058_RS10355	COG0842	Transport permease protein
KU058_RS10360	COG0842	Transport permease protein
KU058_RS10415	COG2226	methyltransferase
KU058_RS10440	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KU058_RS10475	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KU058_RS10485	COG0133	tryptophan synthase activity
KU058_RS10500	COG3706	GGDEF domain
KU058_RS10515	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KU058_RS10520	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KU058_RS10525	COG0022	dehydrogenase e1 component
KU058_RS10530	COG0508	dehydrogenase complex catalyzes the overall conversion of
KU058_RS10535	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KU058_RS10545	COG1063	alcohol dehydrogenase
KU058_RS10550	COG3781	membrane
KU058_RS10560	COG3453	Protein conserved in bacteria
KU058_RS10560	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU058_RS10575	COG0730	response to heat
KU058_RS10590	COG2207	Transcriptional regulator
KU058_RS10590	COG3708	Transcriptional regulator
KU058_RS10595	COG1733	regulation of RNA biosynthetic process
KU058_RS10600	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KU058_RS10610	COG2188	Transcriptional regulator
KU058_RS10625	COG4521	taurine ABC transporter
KU058_RS10630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU058_RS10650	COG0477	Major facilitator Superfamily
KU058_RS10660	COG1027	Aspartate ammonia-lyase
KU058_RS10675	COG0583	DNA-binding transcription factor activity
KU058_RS10680	COG0583	DNA-binding transcription factor activity
KU058_RS10685	COG0183	Belongs to the thiolase family
KU058_RS10690	COG2031	fatty acid transporter
KU058_RS10695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU058_RS10705	COG0583	DNA-binding transcription factor activity
KU058_RS10715	COG2610	gluconate transmembrane transporter activity
KU058_RS10720	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS10730	COG2207	Transcriptional regulator
KU058_RS10745	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS10770	COG0543	2 iron, 2 sulfur cluster binding
KU058_RS10770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KU058_RS10775	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KU058_RS10780	COG4638	Rieske (2fe-2S)
KU058_RS10790	COG0725	ABC transporter, periplasmic molybdate-binding protein
KU058_RS10795	COG4149	molybdate abc transporter
KU058_RS10800	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KU058_RS10890	COG4397	Mu-like prophage major head subunit gpT
KU058_RS10905	COG5005	Phage virion morphogenesis
KU058_RS10910	COG2369	cell adhesion
KU058_RS10915	COG4383	Mu-like prophage protein gp29
KU058_RS10930	COG4373	Mu-like prophage FluMu protein gp28
KU058_RS10965	COG0681	Belongs to the peptidase S26 family
KU058_RS10995	COG3267	Type II secretory pathway component ExeA
KU058_RS10995	COG3409	Peptidoglycan-binding domain 1 protein
KU058_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS11070	COG3433	isochorismatase activity
KU058_RS11070	COG1535	isochorismatase
KU058_RS11130	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KU058_RS11145	COG0753	catalase activity
KU058_RS11155	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KU058_RS11185	COG3539	Fimbrial protein
KU058_RS11305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KU058_RS11325	COG2072	flavoprotein involved in K transport
KU058_RS11335	COG1538	Outer membrane efflux protein
KU058_RS11340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KU058_RS11345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_RS11350	COG0745	RESPONSE REGULATOR receiver
KU058_RS11355	COG2205	protein histidine kinase activity
KU058_RS11370	COG2207	Transcriptional regulator
KU058_RS11385	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS11435	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KU058_RS11555	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU058_RS11575	COG1120	ATPase activity
KU058_RS11580	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KU058_RS11590	COG1064	alcohol dehydrogenase
KU058_RS11605	COG2207	Transcriptional regulator
KU058_RS11610	COG2084	Dehydrogenase
KU058_RS11620	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KU058_RS11625	COG0583	DNA-binding transcription factor activity
KU058_RS11635	COG0129	dihydroxy-acid dehydratase activity
KU058_RS11640	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS11655	COG1566	PFAM secretion protein HlyD family protein
KU058_RS11690	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KU058_RS11720	COG0583	DNA-binding transcription factor activity
KU058_RS11735	COG2188	Transcriptional regulator
KU058_RS11765	COG3210	domain, Protein
KU058_RS11770	COG2831	hemolysin activation secretion protein
KU058_RS11780	COG1473	amidohydrolase
KU058_RS11790	COG0475	glutathione-regulated potassium exporter activity
KU058_RS11790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU058_RS11800	COG0583	DNA-binding transcription factor activity
KU058_RS11805	COG1335	isochorismatase
KU058_RS11815	COG1309	transcriptional regulator
KU058_RS11845	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KU058_RS11855	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_RS11855	COG1902	pentaerythritol trinitrate reductase activity
KU058_RS11860	COG1846	Transcriptional regulator
KU058_RS11880	COG0753	catalase activity
KU058_RS11895	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS11920	COG3162	membrane
KU058_RS11930	COG3829	transcription factor binding
KU058_RS11935	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS11940	COG1960	acyl-CoA dehydrogenase activity
KU058_RS11960	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS11980	COG2186	Transcriptional regulator
KU058_RS11990	COG0583	DNA-binding transcription factor activity
KU058_RS11995	COG4948	Mandelate Racemase Muconate Lactonizing
KU058_RS12000	COG4829	muconolactone delta-isomerase
KU058_RS12010	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU058_RS12015	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU058_RS12020	COG0183	Belongs to the thiolase family
KU058_RS12025	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU058_RS12035	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS12045	COG3733	amine oxidase
KU058_RS12055	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_RS12065	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS12075	COG4638	Rieske (2fe-2S)
KU058_RS12095	COG0154	amidase activity
KU058_RS12105	COG2814	Major facilitator Superfamily
KU058_RS12130	COG1960	acyl-CoA dehydrogenase activity
KU058_RS12135	COG0583	DNA-binding transcription factor activity
KU058_RS12140	COG1414	Transcriptional regulator
KU058_RS12155	COG2391	methyltransferase activity
KU058_RS12165	COG4993	Dehydrogenase
KU058_RS12170	COG3659	wide pore channel activity
KU058_RS12175	COG3420	alginic acid biosynthetic process
KU058_RS12180	COG0710	3-dehydroquinate dehydratase activity
KU058_RS12185	COG3485	protocatechuate 3,4-dioxygenase
KU058_RS12190	COG3485	protocatechuate 3,4-dioxygenase
KU058_RS12195	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KU058_RS12200	COG2271	Major facilitator Superfamily
KU058_RS12205	COG0596	Alpha beta hydrolase
KU058_RS12210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KU058_RS12215	COG0183	Belongs to the thiolase family
KU058_RS12220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KU058_RS12225	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KU058_RS12235	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KU058_RS12240	COG2323	membrane
KU058_RS12285	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_RS12285	COG1902	pentaerythritol trinitrate reductase activity
KU058_RS12310	COG0542	response to heat
KU058_RS12315	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KU058_RS12345	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KU058_RS12350	COG0569	domain protein
KU058_RS12355	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KU058_RS12370	COG4774	siderophore transport
KU058_RS12375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KU058_RS12385	COG1585	Membrane protein implicated in regulation of membrane protease activity
KU058_RS12405	COG1294	oxidase, subunit
KU058_RS12410	COG4890	Cyd operon protein YbgT
KU058_RS12425	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KU058_RS12435	COG0552	protein localization to endoplasmic reticulum
KU058_RS12460	COG0516	GMP reductase activity
KU058_RS12460	COG0517	IMP dehydrogenase activity
KU058_RS12465	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KU058_RS12470	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KU058_RS12480	COG0583	DNA-binding transcription factor activity
KU058_RS12485	COG0024	Methionine aminopeptidase
KU058_RS12515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KU058_RS12515	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU058_RS12520	COG1105	Belongs to the carbohydrate kinase PfkB family
KU058_RS12525	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU058_RS12525	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KU058_RS12525	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KU058_RS12545	COG3300	MHYT domain
KU058_RS12545	COG5001	Diguanylate cyclase
KU058_RS12560	COG2135	peptidase activity
KU058_RS12565	COG0659	secondary active sulfate transmembrane transporter activity
KU058_RS12585	COG1113	amino acid transport
KU058_RS12595	COG1522	sequence-specific DNA binding
KU058_RS12620	COG1011	Hydrolase
KU058_RS12625	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KU058_RS12635	COG2137	regulation of response to DNA damage stimulus
KU058_RS12650	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU058_RS12685	COG0575	Belongs to the CDS family
KU058_RS12690	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KU058_RS12710	COG3852	Histidine kinase
KU058_RS12715	COG2204	response regulator
KU058_RS12780	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU058_RS12785	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KU058_RS12805	COG0697	spore germination
KU058_RS12810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_RS12820	COG0303	'Molybdopterin
KU058_RS12825	COG0521	Mo-molybdopterin cofactor biosynthetic process
KU058_RS12825	COG0315	cyclic pyranopterin monophosphate synthase activity
KU058_RS12840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KU058_RS12845	COG0243	molybdopterin cofactor binding
KU058_RS12855	COG0243	molybdopterin cofactor binding
KU058_RS12860	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_RS12865	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_RS12865	COG2146	nitrite reductase [NAD(P)H] activity
KU058_RS12875	COG0745	RESPONSE REGULATOR receiver
KU058_RS12880	COG1116	anion transmembrane transporter activity
KU058_RS12880	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU058_RS12900	COG0511	ligase activity, forming carbon-carbon bonds
KU058_RS12915	COG2814	Major facilitator Superfamily
KU058_RS12985	COG0739	heme binding
KU058_RS12985	COG0741	lytic transglycosylase activity
KU058_RS12985	COG1196	nuclear chromosome segregation
KU058_RS13130	COG5410	chromosome segregation
KU058_RS13215	COG4197	protein conserved in bacteria, prophage-related
KU058_RS13220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU058_RS13290	COG0069	glutamate synthase activity
KU058_RS13310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KU058_RS13320	COG1454	alcohol dehydrogenase
KU058_RS13325	COG0824	Thioesterase
KU058_RS13335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KU058_RS13350	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU058_RS13355	COG2030	dehydratase
KU058_RS13365	COG0183	Belongs to the thiolase family
KU058_RS13375	COG0583	DNA-binding transcription factor activity
KU058_RS13380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KU058_RS13390	COG1522	sequence-specific DNA binding
KU058_RS13395	COG3135	benzoate transporter
KU058_RS13405	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KU058_RS13430	COG0589	response to stress
KU058_RS13435	COG0488	(ABC) transporter
KU058_RS13455	COG4773	Receptor
KU058_RS13490	COG0668	transmembrane transport
KU058_RS13500	COG1309	transcriptional regulator
KU058_RS13520	COG1605	Chorismate mutase
KU058_RS13530	COG4221	oxidoreductase activity
KU058_RS13540	COG0308	aminopeptidase N
KU058_RS13560	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KU058_RS13570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU058_RS13575	COG1454	alcohol dehydrogenase
KU058_RS13595	COG0531	amino acid
KU058_RS13600	COG4303	Ethanolamine ammonia lyase large subunit
KU058_RS13605	COG4302	ethanolamine ammonia-lyase activity
KU058_RS13610	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU058_RS13610	COG0519	Catalyzes the synthesis of GMP from XMP
KU058_RS13615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU058_RS13625	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KU058_RS13640	COG0697	spore germination
KU058_RS13645	COG1923	regulation of RNA biosynthetic process
KU058_RS13655	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KU058_RS13660	COG0802	atpase or kinase
KU058_RS13680	COG1187	pseudouridine synthase activity
KU058_RS13695	COG0583	DNA-binding transcription factor activity
KU058_RS13710	COG2814	Major facilitator Superfamily
KU058_RS13715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KU058_RS13740	COG0729	surface antigen
KU058_RS13760	COG0174	glutamine synthetase
KU058_RS13765	COG0745	RESPONSE REGULATOR receiver
KU058_RS13770	COG2205	protein histidine kinase activity
KU058_RS13780	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KU058_RS13785	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KU058_RS13810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_RS13815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU058_RS13820	COG1960	acyl-CoA dehydrogenase activity
KU058_RS13835	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU058_RS13840	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU058_RS13860	COG0583	DNA-binding transcription factor activity
KU058_RS13875	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU058_RS13885	COG3658	cytochrome
KU058_RS13890	COG1215	transferase activity, transferring glycosyl groups
KU058_RS13895	COG0726	polysaccharide deacetylase
KU058_RS13895	COG1649	PFAM Uncharacterised BCR, COG1649
KU058_RS13920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KU058_RS13925	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KU058_RS13935	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KU058_RS13960	COG0305	Participates in initiation and elongation during chromosome replication
KU058_RS13965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KU058_RS13975	COG1305	Transglutaminase-like
KU058_RS13985	COG2308	Evidence 4 Homologs of previously reported genes of
KU058_RS14015	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KU058_RS14020	COG0138	bifunctional purine biosynthesis protein purh
KU058_RS14025	COG0151	Belongs to the GarS family
KU058_RS14030	COG1464	Belongs to the NlpA lipoprotein family
KU058_RS14035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KU058_RS14040	COG2011	ABC-type metal ion transport system permease component
KU058_RS14045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU058_RS14055	COG1301	dicarboxylic acid transport
KU058_RS14095	COG4269	membrane
KU058_RS14110	COG1902	pentaerythritol trinitrate reductase activity
KU058_RS14110	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_RS14120	COG2203	Gaf domain
KU058_RS14120	COG5001	Diguanylate cyclase
KU058_RS14120	COG3706	GGDEF domain
KU058_RS14120	COG4251	negative regulation of phosphorylation
KU058_RS14130	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU058_RS14150	COG4172	Belongs to the ABC transporter superfamily
KU058_RS14155	COG4239	(ABC) transporter, permease
KU058_RS14160	COG4174	ABC transporter (Permease)
KU058_RS14170	COG1388	LysM domain
KU058_RS14170	COG0741	lytic transglycosylase activity
KU058_RS14170	COG0741	lytic transglycosylase activity
KU058_RS14170	COG1388	LysM domain
KU058_RS14175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU058_RS14215	COG0583	DNA-binding transcription factor activity
KU058_RS14220	COG1279	arginine transmembrane transporter activity
KU058_RS14240	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_RS14245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_RS14250	COG0006	proline dipeptidase activity
KU058_RS14335	COG0739	heme binding
KU058_RS14335	COG0741	lytic transglycosylase activity
KU058_RS14335	COG1196	nuclear chromosome segregation
KU058_RS14395	COG4695	Portal protein
KU058_RS14495	COG0305	Participates in initiation and elongation during chromosome replication
KU058_RS14510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KU058_RS14565	COG2194	sulfuric ester hydrolase activity
KU058_RS14610	COG0739	heme binding
KU058_RS14935	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KU058_RS14960	COG3384	dioxygenase
KU058_RS14970	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KU058_RS14975	COG2878	Part of a membrane complex involved in electron transport
KU058_RS14980	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KU058_RS15005	COG0768	penicillin binding
KU058_RS15010	COG0742	ribosomal rna small subunit methyltransferase
KU058_RS15025	COG0830	nickel cation binding
KU058_RS15035	COG0804	urea catabolic process
KU058_RS15075	COG1253	flavin adenine dinucleotide binding
KU058_RS15080	COG2851	Citrate transporter
KU058_RS15130	COG1773	rubredoxin
KU058_RS15135	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KU058_RS15145	COG0583	DNA-binding transcription factor activity
KU058_RS15170	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KU058_RS15175	COG4181	ATPase activity
KU058_RS15220	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KU058_RS15240	COG0306	phosphate transporter
KU058_RS15250	COG3958	Transketolase
KU058_RS15255	COG3959	Transketolase, thiamine diphosphate binding domain
KU058_RS15260	COG2271	Major facilitator Superfamily
KU058_RS15265	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS15270	COG0583	DNA-binding transcription factor activity
KU058_RS15285	COG2223	nitrite transmembrane transporter activity
KU058_RS15290	COG2207	Transcriptional regulator
KU058_RS15295	COG2066	Belongs to the glutaminase family
KU058_RS15300	COG0242	peptide deformylase activity
KU058_RS15305	COG0477	Major facilitator Superfamily
KU058_RS15315	COG0028	Belongs to the TPP enzyme family
KU058_RS15330	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS15335	COG2267	carboxylic ester hydrolase activity
KU058_RS15345	COG2271	Major facilitator Superfamily
KU058_RS15350	COG0446	pyridine nucleotide-disulphide oxidoreductase
KU058_RS15360	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS15380	COG1414	Transcriptional regulator
KU058_RS15395	COG1024	Enoyl-CoA hydratase
KU058_RS15405	COG1215	transferase activity, transferring glycosyl groups
KU058_RS15410	COG0726	polysaccharide deacetylase
KU058_RS15410	COG1649	PFAM Uncharacterised BCR, COG1649
KU058_RS15420	COG4681	YaeQ
KU058_RS15430	COG0523	cobalamin synthesis protein
KU058_RS15440	COG1607	acyl-coa hydrolase
KU058_RS15450	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_RS15455	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KU058_RS15460	COG1309	transcriptional regulator
KU058_RS15485	COG2040	homocysteine
KU058_RS15490	COG0531	amino acid
KU058_RS15545	COG1595	DNA-templated transcription, initiation
KU058_RS15555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU058_RS15560	COG0477	Major facilitator Superfamily
KU058_RS15580	COG0084	hydrolase, TatD family'
KU058_RS15615	COG0629	single-stranded DNA binding
KU058_RS15670	COG0582	viral genome integration into host DNA
KU058_RS15700	COG1061	Type III restriction enzyme res subunit
KU058_RS15710	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KU058_RS15715	COG1192	Involved in chromosome partitioning
KU058_RS15725	COG1061	Type III restriction enzyme res subunit
KU058_RS15825	COG0592	DNA-directed DNA polymerase activity
KU058_RS15865	COG2026	Addiction module toxin, RelE StbE family
KU058_RS16015	COG3755	Protein conserved in bacteria
KU058_RS16060	COG1484	DNA-dependent DNA replication
KU058_RS16150	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KU058_RS16220	COG0405	Gamma-glutamyltransferase
KU058_RS16225	COG2814	Major facilitator Superfamily
KU058_RS16235	COG2050	protein possibly involved in aromatic compounds catabolism
KU058_RS16250	COG1090	epimerase
KU058_RS16270	COG0420	3'-5' exonuclease activity
KU058_RS16295	COG0735	belongs to the Fur family
KU058_RS16300	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KU058_RS16320	COG0121	glutamine amidotransferase
KU058_RS16335	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU058_RS16345	COG0210	DNA helicase
KU058_RS16350	COG2885	chlorophyll binding
KU058_RS16355	COG0204	Acyl-transferase
KU058_RS16370	COG2894	cell division
KU058_RS16395	COG1280	lysine exporter protein (LysE YggA)
KU058_RS16400	COG1674	ftsk spoiiie
KU058_RS16400	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KU058_RS16405	COG0492	ferredoxin-NADP+ reductase activity
KU058_RS16410	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KU058_RS16420	COG0456	acetyltransferase
KU058_RS16465	COG1981	membrane
KU058_RS16480	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KU058_RS16480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU058_RS16500	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS16510	COG0657	acetylesterase activity
KU058_RS16520	COG0473	3-isopropylmalate dehydrogenase activity
KU058_RS16525	COG0583	DNA-binding transcription factor activity
KU058_RS16545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KU058_RS16570	COG0564	pseudouridine synthase activity
KU058_RS16580	COG0358	DNA primase activity
KU058_RS16595	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KU058_RS16625	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KU058_RS16655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KU058_RS16665	COG0351	phosphomethylpyrimidine kinase
KU058_RS16665	COG0352	thiamine-phosphate diphosphorylase activity
KU058_RS16665	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KU058_RS16670	COG1652	LysM domain
KU058_RS16695	COG1399	metal-binding, possibly nucleic acid-binding protein
KU058_RS16700	COG3101	peptidyl-lysine hydroxylation
KU058_RS16705	COG0009	L-threonylcarbamoyladenylate synthase
KU058_RS16710	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KU058_RS16715	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KU058_RS16730	COG4106	trans-aconitate 2-methyltransferase activity
KU058_RS16745	COG2226	methyltransferase
KU058_RS16745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU058_RS16745	COG0596	Alpha beta hydrolase
KU058_RS16750	COG1877	trehalose-phosphatase activity
KU058_RS16755	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KU058_RS16760	COG2223	nitrite transmembrane transporter activity
KU058_RS16780	COG1196	nuclear chromosome segregation
KU058_RS16790	COG0730	response to heat
KU058_RS16805	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KU058_RS16815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU058_RS16865	COG0489	protein tyrosine kinase activity
KU058_RS16875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU058_RS16875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU058_RS16905	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KU058_RS16910	COG2081	HI0933 family
KU058_RS16920	COG0668	transmembrane transport
KU058_RS16940	COG0583	DNA-binding transcription factor activity
KU058_RS16960	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KU058_RS16965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU058_RS16995	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KU058_RS17035	COG0745	RESPONSE REGULATOR receiver
KU058_RS17055	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KU058_RS17090	COG0384	phenazine biosynthesis protein PhzF
KU058_RS17115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KU058_RS17130	COG0583	DNA-binding transcription factor activity
KU058_RS17160	COG0583	DNA-binding transcription factor activity
KU058_RS17175	COG0583	DNA-binding transcription factor activity
KU058_RS17180	COG1053	succinate dehydrogenase
KU058_RS17190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KU058_RS17195	COG2814	Major facilitator Superfamily
KU058_RS17200	COG1960	acyl-CoA dehydrogenase activity
KU058_RS17205	COG0583	DNA-binding transcription factor activity
KU058_RS17210	COG1063	alcohol dehydrogenase
KU058_RS17240	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KU058_RS17245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KU058_RS17250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU058_RS17265	COG3667	copper resistance
KU058_RS17270	COG2132	Multicopper oxidase
KU058_RS17280	COG0561	phosphatase activity
KU058_RS17285	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KU058_RS17310	COG1214	PFAM Peptidase M22, glycoprotease
KU058_RS17360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KU058_RS17370	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KU058_RS17375	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KU058_RS17380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KU058_RS17440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KU058_RS17450	COG1846	Transcriptional regulator
KU058_RS17455	COG1764	response to oxidative stress
KU058_RS17495	COG0037	tRNA processing
KU058_RS17505	COG0248	Ppx GppA phosphatase
KU058_RS17535	COG0072	phenylalanine-tRNA ligase activity
KU058_RS17580	COG1238	metal cluster binding
KU058_RS17585	COG0625	glutathione transferase activity
KU058_RS17600	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_RS17605	COG3028	Belongs to the UPF0307 family
KU058_RS17610	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KU058_RS17630	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KU058_RS17635	COG0617	tRNA 3'-terminal CCA addition
KU058_RS17640	COG1555	photosystem II stabilization
KU058_RS17645	COG3956	TIGRFAM MazG family protein
KU058_RS17655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KU058_RS17675	COG0784	Response regulator, receiver
KU058_RS17675	COG2205	protein histidine kinase activity
KU058_RS17675	COG5002	protein histidine kinase activity
KU058_RS17680	COG1024	Enoyl-CoA hydratase
KU058_RS17685	COG2084	Dehydrogenase
KU058_RS17690	COG3622	Belongs to the hyi family
KU058_RS17720	COG0697	spore germination
KU058_RS17730	COG2814	Major facilitator Superfamily
KU058_RS17735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KU058_RS17745	COG0583	DNA-binding transcription factor activity
KU058_RS17755	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KU058_RS17770	COG0084	hydrolase, TatD family'
KU058_RS17785	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KU058_RS17815	COG0440	acetolactate synthase activity
KU058_RS17820	COG0028	Belongs to the TPP enzyme family
KU058_RS17845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KU058_RS17850	COG0577	efflux transmembrane transporter activity
KU058_RS17850	COG1136	(ABC) transporter
KU058_RS17855	COG1538	Outer membrane efflux protein
KU058_RS17870	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KU058_RS17875	COG1162	GTPase activity
KU058_RS17885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KU058_RS17905	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
KU058_RS17910	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS17950	COG2986	histidine ammonia-lyase
KU058_RS17965	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_RS17975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU058_RS18020	COG1426	Protein conserved in bacteria
KU058_RS18055	COG0793	Belongs to the peptidase S41A family
KU058_RS18070	COG2267	carboxylic ester hydrolase activity
KU058_RS18080	COG1012	belongs to the aldehyde dehydrogenase family
KU058_RS18085	COG3265	gluconokinase activity
KU058_RS18095	COG0800	Aldolase
KU058_RS18105	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KU058_RS18110	COG0280	phosphate acetyltransferase
KU058_RS18110	COG0857	belongs to the CobB CobQ family
KU058_RS18115	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KU058_RS18115	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KU058_RS18135	COG0740	serine-type endopeptidase activity
KU058_RS18145	COG4774	siderophore transport
KU058_RS18155	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KU058_RS18165	COG2813	Specifically methylates the guanine in position
KU058_RS18165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KU058_RS18265	COG0788	formyltetrahydrofolate deformylase activity
KU058_RS18290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU058_RS18290	COG4651	solute:proton antiporter activity
KU058_RS18310	COG0724	RNA recognition motif
KU058_RS18315	COG0210	DNA helicase
KU058_RS18340	COG1733	regulation of RNA biosynthetic process
KU058_RS18350	COG2900	Belongs to the SlyX family
KU058_RS18355	COG0488	(ABC) transporter
KU058_RS18360	COG1280	lysine exporter protein (LysE YggA)
KU058_RS18365	COG1560	Kdo2-lipid A biosynthetic process
KU058_RS18375	COG1301	dicarboxylic acid transport
KU058_RS18430	COG0473	3-isopropylmalate dehydrogenase activity
KU058_RS18495	COG0583	DNA-binding transcription factor activity
KU058_RS18505	COG0625	glutathione transferase activity
KU058_RS18510	COG2378	regulation of single-species biofilm formation
KU058_RS18515	COG0546	phosphoglycolate phosphatase activity
KU058_RS18525	COG1530	ribonuclease E activity
KU058_RS18530	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_RS18545	COG0583	DNA-binding transcription factor activity
KU058_RS18550	COG4221	oxidoreductase activity
KU058_RS18555	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KU058_RS18565	COG0534	Mate efflux family protein
KU058_RS18580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KU058_RS18620	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KU058_RS18625	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KU058_RS18640	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KU058_RS18650	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KU058_RS18650	COG0644	oxidoreductase
KU058_RS18655	COG0425	Belongs to the sulfur carrier protein TusA family
KU058_RS18660	COG4535	Mg2 and Co2 transporter CorC
KU058_RS18670	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KU058_RS18690	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KU058_RS18695	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KU058_RS18695	COG0475	glutathione-regulated potassium exporter activity
KU058_RS18700	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
KU058_RS18710	COG0484	heat shock protein binding
KU058_RS18715	COG0789	Transcriptional regulator
KU058_RS18720	COG0598	Magnesium transport protein CorA
KU058_RS18735	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KU058_RS18740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KU058_RS18745	COG1074	ATP-dependent DNA helicase activity
KU058_RS18750	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KU058_RS18770	COG2226	methyltransferase
KU058_RS18785	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KU058_RS18790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KU058_RS18805	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KU058_RS18805	COG2111	Na H antiporter
KU058_RS18810	COG1006	Multisubunit Na H antiporter MnhC subunit
KU058_RS18815	COG0651	ATP synthesis coupled electron transport
KU058_RS18820	COG1863	multisubunit Na H antiporter MnhE subunit
KU058_RS18825	COG2212	antiporter activity
KU058_RS18830	COG1320	monovalent cation:proton antiporter activity
KU058_RS18845	COG0195	Participates in both transcription termination and antitermination
KU058_RS18895	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KU058_RS18900	COG0237	dephospho-CoA kinase activity
KU058_RS18910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KU058_RS18925	COG0497	DNA recombination
KU058_RS18935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KU058_RS18965	COG2169	Transcriptional regulator
KU058_RS18965	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KU058_RS18970	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KU058_RS19035	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KU058_RS19050	COG0326	Molecular chaperone. Has ATPase activity
KU058_RS19065	COG2056	Na+-H+ antiporter family
KU058_RS19070	COG0596	Alpha beta hydrolase
KU058_RS19165	COG0546	phosphoglycolate phosphatase activity
KU058_RS19170	COG1716	ATPase activity
KU058_RS19215	COG0181	hydroxymethylbilane synthase activity
KU058_RS19225	COG3275	phosphorelay sensor kinase activity
KU058_RS19245	COG1538	Outer membrane efflux protein
KU058_RS19250	COG0697	spore germination
KU058_RS19275	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KU058_RS19280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KU058_RS19285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KU058_RS19290	COG0772	Belongs to the SEDS family
KU058_RS19315	COG4974	Belongs to the 'phage' integrase family
KU058_RS19320	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU058_RS19330	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KU058_RS19340	COG2197	response regulator
KU058_RS19355	COG0793	Belongs to the peptidase S41A family
KU058_RS19360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KU058_RS19365	COG0795	lipopolysaccharide-transporting ATPase activity
KU058_RS19405	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU058_RS19405	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KU058_RS19415	COG0004	ammonium transporteR
KU058_RS19420	COG0347	Belongs to the P(II) protein family
KU058_RS19440	COG0659	secondary active sulfate transmembrane transporter activity
KU058_RS19445	COG0589	response to stress
KU058_RS19485	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU058_RS19530	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KU058_RS19600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KU058_RS19610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KU058_RS19630	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KU058_RS19645	COG0318	PFAM AMP-dependent synthetase and ligase
KU058_RS19655	COG0477	Major facilitator Superfamily
KU058_RS19660	COG2860	membrane
KU058_RS19670	COG1253	flavin adenine dinucleotide binding
KU058_RS19690	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KU058_RS19730	COG0655	NAD(P)H dehydrogenase (quinone) activity
KU058_RS19740	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KU058_RS19810	COG0758	DNA mediated transformation
KU058_RS19820	COG0697	spore germination
KU058_RS19825	COG1309	transcriptional regulator
KU058_RS19840	COG0386	Belongs to the glutathione peroxidase family
KU058_RS19905	COG1121	(ABC) transporter
KU058_RS19910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KU058_RS19915	COG1280	lysine exporter protein (LysE YggA)
KU058_RS19920	COG2837	iron assimilation
KU058_RS19930	COG0281	malic enzyme
KU058_RS19975	COG0519	Catalyzes the synthesis of GMP from XMP
KU058_RS19975	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KU058_RS19980	COG4399	Belongs to the UPF0754 family
KU058_RS19985	COG2259	Doxx family
KU058_RS19990	COG0586	Pfam SNARE associated Golgi protein
KU058_RS20005	COG1192	Involved in chromosome partitioning
KU058_RS20015	COG0271	Belongs to the BolA IbaG family
KU058_RS20035	COG2267	carboxylic ester hydrolase activity
KU058_RS20055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KU058_RS20055	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KU058_RS20055	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KU058_RS20055	COG3321	synthase
KU058_RS20060	COG1960	acyl-CoA dehydrogenase activity
KU058_RS20070	COG2197	response regulator
KU058_RS20080	COG3916	Acyl-homoserine-lactone synthase
KU058_RS20085	COG0477	Major facilitator Superfamily
KU058_RS20090	COG1024	Enoyl-CoA hydratase
KU058_RS20095	COG1024	Enoyl-CoA hydratase
KU058_RS20100	COG1960	acyl-CoA dehydrogenase activity
KU058_RS20105	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KU058_RS20125	COG1113	amino acid transport
KU058_RS20130	COG1113	amino acid transport
KU058_RS20135	COG0251	oxidation-reduction process
KU058_RS20175	COG0564	pseudouridine synthase activity
KU058_RS20235	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KU058_RS20250	COG1802	Transcriptional regulator
KU058_RS20260	COG1448	Aminotransferase
KU058_RS20265	COG0277	FAD linked oxidase domain protein
KU058_RS20275	COG2186	Transcriptional regulator
KU058_RS20285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KU058_RS20290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KU058_RS20305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KU058_RS20310	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KU058_RS20335	COG2244	polysaccharide biosynthetic process
KU058_RS20340	COG1083	cytidylyl-transferase
KU058_RS20345	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KU058_RS20355	COG2089	acid synthase
KU058_RS20360	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
KU058_RS20365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
KU058_RS20375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KU058_RS20380	COG1596	polysaccharide export
KU058_RS20405	COG0728	peptidoglycan biosynthetic process
KU058_RS20410	COG3023	N-Acetylmuramoyl-L-alanine amidase
KU058_RS20470	COG0546	phosphoglycolate phosphatase activity
KU058_RS20475	COG1028	Short-chain dehydrogenase reductase Sdr
KU058_RS20495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU058_RS20500	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KU058_RS20505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KU058_RS20510	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KU058_RS20515	COG1116	anion transmembrane transporter activity
KU058_RS20520	COG1309	transcriptional regulator
KU058_RS20525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KU058_RS20535	COG0196	riboflavin kinase activity
KU058_RS20540	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KU058_RS20550	COG1047	Peptidyl-prolyl cis-trans
KU058_RS20590	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KU058_RS20595	COG0657	acetylesterase activity
KU058_RS20615	COG0583	DNA-binding transcription factor activity
KU058_RS20645	COG2951	lytic endotransglycosylase activity
KU058_RS20650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KU058_RS20665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KU058_RS20675	COG0671	phosphoesterase, PA-phosphatase related
KU058_RS20680	COG0861	Integral membrane protein TerC family
KU058_RS20690	COG0754	glutathionylspermidine amidase activity
KU058_RS20700	COG0402	S-adenosylhomocysteine deaminase activity
KU058_RS20715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KU058_RS20720	COG1230	cation diffusion facilitator family transporter
KU058_RS20735	COG0706	membrane insertase activity
KU058_RS20770	COG4683	PFAM Phage derived protein Gp49-like (DUF891)