locus-tag	class	description
HFD79_RS00010	COG0592	DNA-directed DNA polymerase activity
HFD79_RS00020	COG0187	DNA topoisomerase II activity
HFD79_RS00030	COG0586	Pfam SNARE associated Golgi protein
HFD79_RS00035	COG0488	(ABC) transporter
HFD79_RS00060	COG0596	Alpha beta hydrolase
HFD79_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HFD79_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HFD79_RS00115	COG0733	neurotransmitter:sodium symporter activity
HFD79_RS00155	COG2233	PERMEase
HFD79_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD79_RS00205	COG2814	Major facilitator Superfamily
HFD79_RS00210	COG0656	L-ascorbic acid biosynthetic process
HFD79_RS00215	COG0583	DNA-binding transcription factor activity
HFD79_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD79_RS00235	COG1064	alcohol dehydrogenase
HFD79_RS00240	COG2818	Glycosylase
HFD79_RS00255	COG1194	a g-specific adenine glycosylase
HFD79_RS00275	COG2983	Belongs to the UPF0260 family
HFD79_RS00280	COG2133	pyrroloquinoline quinone binding
HFD79_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HFD79_RS00290	COG2116	formate transmembrane transporter activity
HFD79_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFD79_RS00315	COG1335	isochorismatase
HFD79_RS00320	COG0385	Bile acid
HFD79_RS00325	COG0534	Mate efflux family protein
HFD79_RS00330	COG1683	Conserved Protein
HFD79_RS00350	COG0625	glutathione transferase activity
HFD79_RS00360	COG1113	amino acid transport
HFD79_RS00370	COG0523	cobalamin synthesis protein
HFD79_RS00380	COG2188	Transcriptional regulator
HFD79_RS00410	COG0010	Belongs to the arginase family
HFD79_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HFD79_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HFD79_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HFD79_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HFD79_RS00545	COG0534	Mate efflux family protein
HFD79_RS00550	COG0436	Aminotransferase
HFD79_RS00555	COG2733	membrane
HFD79_RS00570	COG2918	glutathione biosynthetic process
HFD79_RS00580	COG3501	Rhs element vgr protein
HFD79_RS00585	COG0791	NLP P60 protein
HFD79_RS00585	COG1388	LysM domain
HFD79_RS00600	COG3150	esterase
HFD79_RS00610	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HFD79_RS00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD79_RS00635	COG2233	PERMEase
HFD79_RS00640	COG2351	hydroxyisourate hydrolase activity
HFD79_RS00675	COG3706	GGDEF domain
HFD79_RS00690	COG1393	Belongs to the ArsC family
HFD79_RS00695	COG0708	Exodeoxyribonuclease III
HFD79_RS00715	COG0189	ligase activity
HFD79_RS00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HFD79_RS00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HFD79_RS00760	COG4942	peptidase
HFD79_RS00770	COG0508	dehydrogenase complex catalyzes the overall conversion of
HFD79_RS00780	COG2119	membrane
HFD79_RS00790	COG2433	Pfam Transposase IS66
HFD79_RS00810	COG0426	domain, Protein
HFD79_RS00810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD79_RS00835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HFD79_RS00855	COG1902	pentaerythritol trinitrate reductase activity
HFD79_RS00860	COG1519	Transferase
HFD79_RS00865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HFD79_RS00870	COG0668	transmembrane transport
HFD79_RS00880	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HFD79_RS00885	COG1335	isochorismatase
HFD79_RS00890	COG1522	sequence-specific DNA binding
HFD79_RS00895	COG3328	transposase activity
HFD79_RS00920	COG2205	protein histidine kinase activity
HFD79_RS00920	COG2198	Histidine kinase
HFD79_RS00920	COG0784	Response regulator, receiver
HFD79_RS00925	COG3162	membrane
HFD79_RS00930	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFD79_RS00940	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD79_RS00950	COG3706	GGDEF domain
HFD79_RS00960	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HFD79_RS00965	COG1309	transcriptional regulator
HFD79_RS00985	COG0352	thiamine-phosphate diphosphorylase activity
HFD79_RS00985	COG0351	phosphomethylpyrimidine kinase
HFD79_RS00985	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFD79_RS00995	COG2814	Major facilitator Superfamily
HFD79_RS01010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HFD79_RS01020	COG1113	amino acid transport
HFD79_RS01030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFD79_RS01035	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS01045	COG1335	isochorismatase
HFD79_RS01060	COG1061	Type III restriction enzyme res subunit
HFD79_RS01070	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HFD79_RS01075	COG1192	Involved in chromosome partitioning
HFD79_RS01085	COG1061	Type III restriction enzyme res subunit
HFD79_RS01125	COG2814	Major facilitator Superfamily
HFD79_RS01130	COG0583	DNA-binding transcription factor activity
HFD79_RS01150	COG0667	Aldo Keto reductase
HFD79_RS01180	COG1733	regulation of RNA biosynthetic process
HFD79_RS01185	COG2249	NAD(P)H dehydrogenase (quinone) activity
HFD79_RS01250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HFD79_RS01265	COG2329	Antibiotic biosynthesis monooxygenase
HFD79_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HFD79_RS01325	COG0427	acetyl-CoA hydrolase
HFD79_RS01340	COG0745	RESPONSE REGULATOR receiver
HFD79_RS01350	COG0659	secondary active sulfate transmembrane transporter activity
HFD79_RS01355	COG4221	oxidoreductase activity
HFD79_RS01360	COG2873	o-acetylhomoserine
HFD79_RS01365	COG0488	(ABC) transporter
HFD79_RS01450	COG0833	amino acid
HFD79_RS01495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HFD79_RS01500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HFD79_RS01515	COG2226	methyltransferase
HFD79_RS01565	COG0069	glutamate synthase activity
HFD79_RS01565	COG0067	glutamate synthase
HFD79_RS01565	COG0070	glutamate synthase
HFD79_RS01570	COG0493	'glutamate synthase
HFD79_RS01580	COG1704	LemA family
HFD79_RS01585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HFD79_RS01605	COG3307	-O-antigen
HFD79_RS01625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFD79_RS01640	COG0194	GDP metabolic process
HFD79_RS01690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HFD79_RS01710	COG5380	lipid catabolic process
HFD79_RS01715	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HFD79_RS01740	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HFD79_RS01745	COG0277	FAD linked oxidase domain protein
HFD79_RS01755	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HFD79_RS01760	COG2249	NAD(P)H dehydrogenase (quinone) activity
HFD79_RS01775	COG1289	transmembrane transporter activity
HFD79_RS01785	COG0628	permease
HFD79_RS01790	COG1192	Involved in chromosome partitioning
HFD79_RS01820	COG0833	amino acid
HFD79_RS01825	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HFD79_RS01830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HFD79_RS01840	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS01880	COG0583	DNA-binding transcription factor activity
HFD79_RS01925	COG0517	IMP dehydrogenase activity
HFD79_RS01930	COG1983	PspC domain protein
HFD79_RS01940	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS01955	COG0408	coproporphyrinogen oxidase activity
HFD79_RS01975	COG0513	Belongs to the DEAD box helicase family
HFD79_RS01985	COG1127	ABC transporter
HFD79_RS01990	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HFD79_RS02000	COG2854	intermembrane phospholipid transfer
HFD79_RS02010	COG0598	Magnesium transport protein CorA
HFD79_RS02020	COG0494	nUDIX hydrolase
HFD79_RS02025	COG1040	competence protein
HFD79_RS02030	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HFD79_RS02050	COG1946	Acyl-CoA thioesterase
HFD79_RS02055	COG1301	dicarboxylic acid transport
HFD79_RS02070	COG1959	2 iron, 2 sulfur cluster binding
HFD79_RS02075	COG1017	nitric oxide dioxygenase activity
HFD79_RS02075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFD79_RS02080	COG0433	COG0433 Predicted ATPase
HFD79_RS02085	COG0626	cystathionine gamma-synthase activity
HFD79_RS02240	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS02245	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HFD79_RS02275	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HFD79_RS02280	COG0339	signal peptide processing
HFD79_RS02285	COG0557	exoribonuclease II activity
HFD79_RS02330	COG0179	Fumarylacetoacetate (FAA) hydrolase
HFD79_RS02335	COG2169	Transcriptional regulator
HFD79_RS02340	COG0697	spore germination
HFD79_RS02345	COG1295	ribonuclease BN
HFD79_RS02380	COG1702	phosphate starvation-inducible protein PhoH
HFD79_RS02390	COG1196	nuclear chromosome segregation
HFD79_RS02390	COG0741	lytic transglycosylase activity
HFD79_RS02390	COG0739	heme binding
HFD79_RS02420	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HFD79_RS02425	COG1183	phosphatidylcholine synthase activity
HFD79_RS02470	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS02475	COG1309	transcriptional regulator
HFD79_RS02490	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HFD79_RS02495	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS02515	COG2969	positive regulation of protein catabolic process
HFD79_RS02525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HFD79_RS02540	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HFD79_RS02545	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HFD79_RS02565	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HFD79_RS02575	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFD79_RS02580	COG1408	metallophosphoesterase
HFD79_RS02590	COG2199	diguanylate cyclase activity
HFD79_RS02650	COG1607	acyl-coa hydrolase
HFD79_RS02680	COG2350	Protein conserved in bacteria
HFD79_RS02690	COG0613	PHP domain protein
HFD79_RS02695	COG3781	membrane
HFD79_RS02705	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HFD79_RS02710	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HFD79_RS02720	COG1862	Preprotein translocase
HFD79_RS02765	COG2205	protein histidine kinase activity
HFD79_RS02770	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HFD79_RS02790	COG0726	polysaccharide deacetylase
HFD79_RS02795	COG0463	Glycosyl transferase, family 2
HFD79_RS02800	COG0438	transferase activity, transferring glycosyl groups
HFD79_RS02870	COG0625	glutathione transferase activity
HFD79_RS02875	COG0583	DNA-binding transcription factor activity
HFD79_RS02880	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS02885	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS02895	COG2205	protein histidine kinase activity
HFD79_RS02900	COG0745	RESPONSE REGULATOR receiver
HFD79_RS02905	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HFD79_RS02925	COG2096	Adenosyltransferase
HFD79_RS02975	COG0285	dihydrofolate synthase activity
HFD79_RS02995	COG0450	alkyl hydroperoxide reductase
HFD79_RS03010	COG0477	Major facilitator Superfamily
HFD79_RS03015	COG1272	protein, Hemolysin III
HFD79_RS03050	COG0183	Belongs to the thiolase family
HFD79_RS03055	COG2207	Transcriptional regulator
HFD79_RS03075	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD79_RS03095	COG0183	Belongs to the thiolase family
HFD79_RS03105	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HFD79_RS03105	COG2885	chlorophyll binding
HFD79_RS03115	COG1690	Belongs to the RtcB family
HFD79_RS03120	COG0833	amino acid
HFD79_RS03130	COG2233	PERMEase
HFD79_RS03160	COG2094	Belongs to the DNA glycosylase MPG family
HFD79_RS03165	COG4772	TonB-dependent receptor
HFD79_RS03180	COG1902	pentaerythritol trinitrate reductase activity
HFD79_RS03185	COG0679	Auxin Efflux Carrier
HFD79_RS03195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HFD79_RS03200	COG0354	folic acid binding
HFD79_RS03210	COG3189	MarR family transcriptional regulator
HFD79_RS03215	COG2824	Alkylphosphonate utilization operon protein PhnA
HFD79_RS03220	COG3422	double-strand break repair
HFD79_RS03260	COG0840	transmembrane signaling receptor activity
HFD79_RS03280	COG5510	response to toxic substance
HFD79_RS03290	COG2832	Protein of unknown function (DUF454)
HFD79_RS03295	COG1376	ErfK ybiS ycfS ynhG family protein
HFD79_RS03335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HFD79_RS03345	COG1289	transmembrane transporter activity
HFD79_RS03350	COG2814	Major facilitator Superfamily
HFD79_RS03370	COG1115	amino acid carrier protein
HFD79_RS03375	COG1752	Esterase of the alpha-beta hydrolase superfamily
HFD79_RS03380	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HFD79_RS03385	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HFD79_RS03415	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFD79_RS03425	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HFD79_RS03430	COG1077	Cell shape determining protein MreB Mrl
HFD79_RS03435	COG1792	Involved in formation and maintenance of cell shape
HFD79_RS03440	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HFD79_RS03445	COG0424	maF-like protein
HFD79_RS03450	COG1530	ribonuclease E activity
HFD79_RS03460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HFD79_RS03470	COG0560	Phosphoserine phosphatase
HFD79_RS03480	COG2249	NAD(P)H dehydrogenase (quinone) activity
HFD79_RS03505	COG2207	Transcriptional regulator
HFD79_RS03525	COG1113	amino acid transport
HFD79_RS03530	COG2828	Protein conserved in bacteria
HFD79_RS03535	COG0142	geranyltranstransferase activity
HFD79_RS03540	COG2315	Protein conserved in bacteria
HFD79_RS03555	COG1752	Esterase of the alpha-beta hydrolase superfamily
HFD79_RS03575	COG2194	sulfuric ester hydrolase activity
HFD79_RS03580	COG0745	RESPONSE REGULATOR receiver
HFD79_RS03585	COG0642	Histidine kinase
HFD79_RS03595	COG0004	ammonium transporteR
HFD79_RS03600	COG0583	DNA-binding transcription factor activity
HFD79_RS03620	COG0525	valine-tRNA ligase activity
HFD79_RS03630	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS03640	COG0393	Putative heavy-metal-binding
HFD79_RS03645	COG0393	Putative heavy-metal-binding
HFD79_RS03650	COG1538	Outer membrane efflux protein
HFD79_RS03660	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD79_RS03665	COG0671	phosphoesterase, PA-phosphatase related
HFD79_RS03695	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HFD79_RS03710	COG1648	precorrin-2 dehydrogenase activity
HFD79_RS03710	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HFD79_RS03715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HFD79_RS03720	COG1733	regulation of RNA biosynthetic process
HFD79_RS03730	COG0531	amino acid
HFD79_RS03745	COG0321	lipoyl(octanoyl) transferase activity
HFD79_RS03750	COG2921	Belongs to the UPF0250 family
HFD79_RS03790	COG2009	succinate dehydrogenase
HFD79_RS03795	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HFD79_RS03800	COG1053	succinate dehydrogenase
HFD79_RS03805	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HFD79_RS03830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFD79_RS03850	COG2354	Protein conserved in bacteria
HFD79_RS03855	COG2321	neutral zinc metallopeptidase
HFD79_RS03895	COG2843	Capsule synthesis protein
HFD79_RS03910	COG0589	response to stress
HFD79_RS03930	COG0505	Belongs to the CarA family
HFD79_RS03955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFD79_RS03960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HFD79_RS04010	COG0477	Major facilitator Superfamily
HFD79_RS04015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HFD79_RS04030	COG1597	lipid kinase activity
HFD79_RS04035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HFD79_RS04060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HFD79_RS04065	COG0584	glycerophosphoryl diester phosphodiesterase
HFD79_RS04085	COG0741	lytic transglycosylase activity
HFD79_RS04105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HFD79_RS04120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HFD79_RS04145	COG0778	Nitroreductase
HFD79_RS04160	COG1929	Belongs to the glycerate kinase type-1 family
HFD79_RS04165	COG0243	molybdopterin cofactor binding
HFD79_RS04170	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HFD79_RS04175	COG3339	Conserved Protein
HFD79_RS04185	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HFD79_RS04200	COG1113	amino acid transport
HFD79_RS04210	COG0019	diaminopimelate decarboxylase activity
HFD79_RS04220	COG1280	lysine exporter protein (LysE YggA)
HFD79_RS04225	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HFD79_RS04255	COG0463	Glycosyl transferase, family 2
HFD79_RS04275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD79_RS04310	COG4591	ABC-type transport system involved in lipoprotein release permease component
HFD79_RS04315	COG1136	(ABC) transporter
HFD79_RS04320	COG2333	competence protein COMEC
HFD79_RS04320	COG0658	competence protein
HFD79_RS04330	COG0616	signal peptide processing
HFD79_RS04330	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HFD79_RS04335	COG0596	Alpha beta hydrolase
HFD79_RS04340	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HFD79_RS04350	COG0628	permease
HFD79_RS04385	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFD79_RS04405	COG0823	Involved in the tonB-independent uptake of proteins
HFD79_RS04425	COG0824	Thioesterase
HFD79_RS04430	COG1473	amidohydrolase
HFD79_RS04450	COG0047	phosphoribosylformylglycinamidine synthase activity
HFD79_RS04450	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HFD79_RS04455	COG2814	Major facilitator Superfamily
HFD79_RS04465	COG1024	Enoyl-CoA hydratase
HFD79_RS04470	COG1051	belongs to the nudix hydrolase family
HFD79_RS04470	COG1056	cytidyltransferase-related domain
HFD79_RS04480	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HFD79_RS04495	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HFD79_RS04510	COG4625	pathogenesis
HFD79_RS04515	COG0583	DNA-binding transcription factor activity
HFD79_RS04520	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HFD79_RS04525	COG4208	sulfate ABC transporter
HFD79_RS04530	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HFD79_RS04540	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HFD79_RS04545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HFD79_RS04550	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HFD79_RS04570	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFD79_RS04585	COG0681	Belongs to the peptidase S26 family
HFD79_RS04600	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HFD79_RS04610	COG1381	Involved in DNA repair and RecF pathway recombination
HFD79_RS04615	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HFD79_RS04625	COG4221	oxidoreductase activity
HFD79_RS04655	COG0436	Aminotransferase
HFD79_RS04675	COG0556	nucleotide-excision repair
HFD79_RS04730	COG2070	2-Nitropropane dioxygenase
HFD79_RS04760	COG1215	transferase activity, transferring glycosyl groups
HFD79_RS04775	COG0415	Belongs to the DNA photolyase family
HFD79_RS04785	COG1252	NADH dehydrogenase
HFD79_RS04790	COG1686	Belongs to the peptidase S11 family
HFD79_RS04805	COG1187	pseudouridine synthase activity
HFD79_RS04830	COG0477	Major facilitator Superfamily
HFD79_RS04835	COG0583	DNA-binding transcription factor activity
HFD79_RS04850	COG0612	Peptidase, M16
HFD79_RS04885	COG0352	thiamine-phosphate diphosphorylase activity
HFD79_RS04920	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFD79_RS04935	COG1309	transcriptional regulator
HFD79_RS04945	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HFD79_RS04950	COG0076	glutamate decarboxylase activity
HFD79_RS04960	COG1522	sequence-specific DNA binding
HFD79_RS04965	COG3961	Belongs to the TPP enzyme family
HFD79_RS04970	COG1113	amino acid transport
HFD79_RS04975	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HFD79_RS04980	COG0573	inorganic phosphate transmembrane transporter activity
HFD79_RS04990	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HFD79_RS04995	COG0616	signal peptide processing
HFD79_RS05030	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HFD79_RS05035	COG1686	Belongs to the peptidase S11 family
HFD79_RS05060	COG0583	DNA-binding transcription factor activity
HFD79_RS05065	COG1067	ATP-dependent peptidase activity
HFD79_RS05110	COG1966	Carbon starvation protein
HFD79_RS05115	COG2879	small protein
HFD79_RS05150	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HFD79_RS05150	COG2508	Transcriptional regulator
HFD79_RS05170	COG1113	amino acid transport
HFD79_RS05175	COG0583	DNA-binding transcription factor activity
HFD79_RS05180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD79_RS05185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD79_RS05195	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS05200	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD79_RS05205	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HFD79_RS05205	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HFD79_RS05240	COG2814	Major facilitator Superfamily
HFD79_RS05245	COG4948	Mandelate Racemase Muconate Lactonizing
HFD79_RS05255	COG1309	transcriptional regulator
HFD79_RS05280	COG1741	Belongs to the pirin family
HFD79_RS05290	COG2964	Protein conserved in bacteria
HFD79_RS05305	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HFD79_RS05310	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HFD79_RS05315	COG4605	iron ion homeostasis
HFD79_RS05320	COG4604	ABC transporter, ATP-binding protein
HFD79_RS05325	COG4607	ABC-type enterochelin transport system periplasmic component
HFD79_RS05330	COG4774	siderophore transport
HFD79_RS05340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HFD79_RS05345	COG1021	2,3-dihydroxybenzoate-AMP ligase
HFD79_RS05350	COG1535	isochorismatase
HFD79_RS05350	COG3433	isochorismatase activity
HFD79_RS05365	COG1132	(ABC) transporter
HFD79_RS05375	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HFD79_RS05385	COG1169	isochorismate synthase
HFD79_RS05400	COG3739	integral membrane protein
HFD79_RS05435	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HFD79_RS05465	COG0308	aminopeptidase N
HFD79_RS05470	COG0512	Glutamine amidotransferase of anthranilate synthase
HFD79_RS05520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFD79_RS05525	COG4197	protein conserved in bacteria, prophage-related
HFD79_RS05640	COG5410	chromosome segregation
HFD79_RS05810	COG0582	viral genome integration into host DNA
HFD79_RS05820	COG3104	oligopeptide transport
HFD79_RS05825	COG0174	glutamine synthetase
HFD79_RS05835	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HFD79_RS05870	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HFD79_RS05875	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HFD79_RS05880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HFD79_RS05900	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HFD79_RS05905	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HFD79_RS05910	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HFD79_RS05925	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS05930	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HFD79_RS05935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFD79_RS05945	COG2223	nitrite transmembrane transporter activity
HFD79_RS05955	COG0024	Methionine aminopeptidase
HFD79_RS05960	COG0052	Belongs to the universal ribosomal protein uS2 family
HFD79_RS05975	COG2207	Transcriptional regulator
HFD79_RS06000	COG2951	lytic endotransglycosylase activity
HFD79_RS06005	COG0772	Belongs to the SEDS family
HFD79_RS06020	COG0842	Transport permease protein
HFD79_RS06025	COG1131	(ABC) transporter
HFD79_RS06070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD79_RS06085	COG4215	(ABC) transporter
HFD79_RS06090	COG4160	amino acid transport
HFD79_RS06095	COG4598	ABC transporter
HFD79_RS06105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HFD79_RS06115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD79_RS06130	COG1720	tRNA m6t6A37 methyltransferase activity
HFD79_RS06150	COG0745	RESPONSE REGULATOR receiver
HFD79_RS06155	COG0642	Histidine kinase
HFD79_RS06165	COG0494	nUDIX hydrolase
HFD79_RS06175	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HFD79_RS06180	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HFD79_RS06185	COG3139	Protein of unknown function (DUF1315)
HFD79_RS06190	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HFD79_RS06195	COG1301	dicarboxylic acid transport
HFD79_RS06200	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS06205	COG2819	hydrolase of the alpha beta superfamily
HFD79_RS06215	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HFD79_RS06225	COG2195	Cleaves the N-terminal amino acid of tripeptides
HFD79_RS06230	COG1234	tRNA 3'-trailer cleavage
HFD79_RS06260	COG2363	Small membrane protein
HFD79_RS06280	COG0513	Belongs to the DEAD box helicase family
HFD79_RS06290	COG0778	Nitroreductase
HFD79_RS06630	COG1286	toxin biosynthetic process
HFD79_RS06655	COG4783	chaperone-mediated protein folding
HFD79_RS06660	COG1610	YqeY-like protein
HFD79_RS06760	COG3111	PFAM Bacterial OB fold (BOF) protein
HFD79_RS06785	COG3243	poly(R)-hydroxyalkanoic acid synthase
HFD79_RS06790	COG0786	glutamate:sodium symporter activity
HFD79_RS06800	COG2186	Transcriptional regulator
HFD79_RS06850	COG0477	Major facilitator Superfamily
HFD79_RS06875	COG2985	domain, Protein
HFD79_RS06885	COG2995	paraquat-inducible protein a
HFD79_RS06890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HFD79_RS06890	COG3008	intermembrane lipid transfer
HFD79_RS06900	COG1794	racemase activity, acting on amino acids and derivatives
HFD79_RS06980	COG1301	dicarboxylic acid transport
HFD79_RS06990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HFD79_RS06995	COG2011	ABC-type metal ion transport system permease component
HFD79_RS07000	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFD79_RS07005	COG1464	Belongs to the NlpA lipoprotein family
HFD79_RS07010	COG0151	Belongs to the GarS family
HFD79_RS07015	COG0138	bifunctional purine biosynthesis protein purh
HFD79_RS07020	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HFD79_RS07050	COG2308	Evidence 4 Homologs of previously reported genes of
HFD79_RS07060	COG1305	Transglutaminase-like
HFD79_RS07070	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HFD79_RS07075	COG0305	Participates in initiation and elongation during chromosome replication
HFD79_RS07100	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HFD79_RS07110	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HFD79_RS07115	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HFD79_RS07140	COG0726	polysaccharide deacetylase
HFD79_RS07140	COG1649	PFAM Uncharacterised BCR, COG1649
HFD79_RS07145	COG1215	transferase activity, transferring glycosyl groups
HFD79_RS07150	COG3658	cytochrome
HFD79_RS07160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFD79_RS07175	COG0583	DNA-binding transcription factor activity
HFD79_RS07195	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HFD79_RS07200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HFD79_RS07215	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS07220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HFD79_RS07225	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD79_RS07250	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HFD79_RS07255	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HFD79_RS07265	COG2205	protein histidine kinase activity
HFD79_RS07270	COG0745	RESPONSE REGULATOR receiver
HFD79_RS07275	COG0174	glutamine synthetase
HFD79_RS07295	COG0729	surface antigen
HFD79_RS07320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HFD79_RS07325	COG2814	Major facilitator Superfamily
HFD79_RS07340	COG0583	DNA-binding transcription factor activity
HFD79_RS07355	COG1187	pseudouridine synthase activity
HFD79_RS07375	COG0802	atpase or kinase
HFD79_RS07380	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HFD79_RS07390	COG1923	regulation of RNA biosynthetic process
HFD79_RS07395	COG0697	spore germination
HFD79_RS07410	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HFD79_RS07420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFD79_RS07425	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HFD79_RS07425	COG0519	Catalyzes the synthesis of GMP from XMP
HFD79_RS07430	COG4302	ethanolamine ammonia-lyase activity
HFD79_RS07435	COG4303	Ethanolamine ammonia lyase large subunit
HFD79_RS07440	COG0531	amino acid
HFD79_RS07460	COG1454	alcohol dehydrogenase
HFD79_RS07465	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HFD79_RS07475	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HFD79_RS07495	COG0308	aminopeptidase N
HFD79_RS07505	COG4221	oxidoreductase activity
HFD79_RS07515	COG1605	Chorismate mutase
HFD79_RS07530	COG1309	transcriptional regulator
HFD79_RS07540	COG0668	transmembrane transport
HFD79_RS07575	COG4773	Receptor
HFD79_RS07595	COG0488	(ABC) transporter
HFD79_RS07600	COG0589	response to stress
HFD79_RS07625	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HFD79_RS07635	COG3135	benzoate transporter
HFD79_RS07640	COG1522	sequence-specific DNA binding
HFD79_RS07650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HFD79_RS07655	COG0583	DNA-binding transcription factor activity
HFD79_RS07665	COG0183	Belongs to the thiolase family
HFD79_RS07675	COG2030	dehydratase
HFD79_RS07695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HFD79_RS07705	COG0824	Thioesterase
HFD79_RS07710	COG1454	alcohol dehydrogenase
HFD79_RS07720	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HFD79_RS07740	COG0069	glutamate synthase activity
HFD79_RS07760	COG2814	Major facilitator Superfamily
HFD79_RS07775	COG0511	ligase activity, forming carbon-carbon bonds
HFD79_RS07795	COG1116	anion transmembrane transporter activity
HFD79_RS07795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HFD79_RS07800	COG0745	RESPONSE REGULATOR receiver
HFD79_RS07810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD79_RS07810	COG2146	nitrite reductase [NAD(P)H] activity
HFD79_RS07815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD79_RS07820	COG0243	molybdopterin cofactor binding
HFD79_RS07830	COG0243	molybdopterin cofactor binding
HFD79_RS07835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HFD79_RS07850	COG0315	cyclic pyranopterin monophosphate synthase activity
HFD79_RS07850	COG0521	Mo-molybdopterin cofactor biosynthetic process
HFD79_RS07855	COG0303	'Molybdopterin
HFD79_RS07865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD79_RS07870	COG0697	spore germination
HFD79_RS07890	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HFD79_RS07895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFD79_RS07950	COG2204	response regulator
HFD79_RS07955	COG3852	Histidine kinase
HFD79_RS07975	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HFD79_RS07980	COG0575	Belongs to the CDS family
HFD79_RS08015	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HFD79_RS08030	COG2137	regulation of response to DNA damage stimulus
HFD79_RS08040	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HFD79_RS08045	COG1011	Hydrolase
HFD79_RS08070	COG1522	sequence-specific DNA binding
HFD79_RS08080	COG1113	amino acid transport
HFD79_RS08095	COG0659	secondary active sulfate transmembrane transporter activity
HFD79_RS08100	COG2135	peptidase activity
HFD79_RS08115	COG5001	Diguanylate cyclase
HFD79_RS08115	COG3300	MHYT domain
HFD79_RS08135	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HFD79_RS08135	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HFD79_RS08135	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HFD79_RS08140	COG1105	Belongs to the carbohydrate kinase PfkB family
HFD79_RS08145	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HFD79_RS08145	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HFD79_RS08175	COG0024	Methionine aminopeptidase
HFD79_RS08180	COG0583	DNA-binding transcription factor activity
HFD79_RS08190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HFD79_RS08195	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HFD79_RS08200	COG0517	IMP dehydrogenase activity
HFD79_RS08200	COG0516	GMP reductase activity
HFD79_RS08225	COG0552	protein localization to endoplasmic reticulum
HFD79_RS08235	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HFD79_RS08250	COG4890	Cyd operon protein YbgT
HFD79_RS08255	COG1294	oxidase, subunit
HFD79_RS08270	COG1585	Membrane protein implicated in regulation of membrane protease activity
HFD79_RS08280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HFD79_RS08285	COG4774	siderophore transport
HFD79_RS08300	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HFD79_RS08305	COG0569	domain protein
HFD79_RS08310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HFD79_RS08340	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HFD79_RS08345	COG0542	response to heat
HFD79_RS08370	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD79_RS08370	COG1902	pentaerythritol trinitrate reductase activity
HFD79_RS08415	COG2323	membrane
HFD79_RS08420	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HFD79_RS08430	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFD79_RS08435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HFD79_RS08440	COG0183	Belongs to the thiolase family
HFD79_RS08445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HFD79_RS08450	COG0596	Alpha beta hydrolase
HFD79_RS08455	COG2271	Major facilitator Superfamily
HFD79_RS08460	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HFD79_RS08465	COG3485	protocatechuate 3,4-dioxygenase
HFD79_RS08470	COG3485	protocatechuate 3,4-dioxygenase
HFD79_RS08475	COG0710	3-dehydroquinate dehydratase activity
HFD79_RS08480	COG3420	alginic acid biosynthetic process
HFD79_RS08485	COG3659	wide pore channel activity
HFD79_RS08490	COG4993	Dehydrogenase
HFD79_RS08500	COG2391	methyltransferase activity
HFD79_RS08515	COG1414	Transcriptional regulator
HFD79_RS08520	COG0583	DNA-binding transcription factor activity
HFD79_RS08525	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS08550	COG2814	Major facilitator Superfamily
HFD79_RS08560	COG0154	amidase activity
HFD79_RS08580	COG4638	Rieske (2fe-2S)
HFD79_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS08600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD79_RS08610	COG3733	amine oxidase
HFD79_RS08620	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS08630	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFD79_RS08635	COG0183	Belongs to the thiolase family
HFD79_RS08640	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HFD79_RS08645	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFD79_RS08655	COG4829	muconolactone delta-isomerase
HFD79_RS08660	COG4948	Mandelate Racemase Muconate Lactonizing
HFD79_RS08665	COG0583	DNA-binding transcription factor activity
HFD79_RS08675	COG2186	Transcriptional regulator
HFD79_RS08695	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS08715	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS08720	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS08725	COG3829	transcription factor binding
HFD79_RS08735	COG3162	membrane
HFD79_RS08750	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS08765	COG0753	catalase activity
HFD79_RS08785	COG1846	Transcriptional regulator
HFD79_RS08790	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD79_RS08790	COG1902	pentaerythritol trinitrate reductase activity
HFD79_RS08800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HFD79_RS08830	COG1309	transcriptional regulator
HFD79_RS08840	COG1335	isochorismatase
HFD79_RS08845	COG0583	DNA-binding transcription factor activity
HFD79_RS08855	COG0475	glutathione-regulated potassium exporter activity
HFD79_RS08855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HFD79_RS08865	COG1473	amidohydrolase
HFD79_RS08875	COG2831	hemolysin activation secretion protein
HFD79_RS08880	COG3210	domain, Protein
HFD79_RS08910	COG2188	Transcriptional regulator
HFD79_RS08925	COG0583	DNA-binding transcription factor activity
HFD79_RS08955	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HFD79_RS08975	COG1566	PFAM secretion protein HlyD family protein
HFD79_RS08990	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS08995	COG0129	dihydroxy-acid dehydratase activity
HFD79_RS09005	COG0583	DNA-binding transcription factor activity
HFD79_RS09010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HFD79_RS09020	COG2084	Dehydrogenase
HFD79_RS09025	COG2207	Transcriptional regulator
HFD79_RS09040	COG1064	alcohol dehydrogenase
HFD79_RS09055	COG1120	ATPase activity
HFD79_RS09075	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFD79_RS09190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HFD79_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS09255	COG2207	Transcriptional regulator
HFD79_RS09265	COG2205	protein histidine kinase activity
HFD79_RS09270	COG0745	RESPONSE REGULATOR receiver
HFD79_RS09275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD79_RS09280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HFD79_RS09285	COG1538	Outer membrane efflux protein
HFD79_RS09295	COG2072	flavoprotein involved in K transport
HFD79_RS09315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HFD79_RS09335	COG3539	Fimbrial protein
HFD79_RS09365	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HFD79_RS09375	COG0753	catalase activity
HFD79_RS09390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HFD79_RS09455	COG3433	isochorismatase activity
HFD79_RS09455	COG1535	isochorismatase
HFD79_RS09460	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS09465	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HFD79_RS09470	COG4149	molybdate abc transporter
HFD79_RS09475	COG0725	ABC transporter, periplasmic molybdate-binding protein
HFD79_RS09485	COG4638	Rieske (2fe-2S)
HFD79_RS09490	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HFD79_RS09495	COG0543	2 iron, 2 sulfur cluster binding
HFD79_RS09495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFD79_RS09520	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS09535	COG2207	Transcriptional regulator
HFD79_RS09545	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS09550	COG2610	gluconate transmembrane transporter activity
HFD79_RS09560	COG0583	DNA-binding transcription factor activity
HFD79_RS09570	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HFD79_RS09575	COG2031	fatty acid transporter
HFD79_RS09580	COG0183	Belongs to the thiolase family
HFD79_RS09585	COG0583	DNA-binding transcription factor activity
HFD79_RS09590	COG0583	DNA-binding transcription factor activity
HFD79_RS09605	COG1027	Aspartate ammonia-lyase
HFD79_RS09615	COG0477	Major facilitator Superfamily
HFD79_RS09635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HFD79_RS09640	COG4521	taurine ABC transporter
HFD79_RS09655	COG2188	Transcriptional regulator
HFD79_RS09665	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HFD79_RS09670	COG1733	regulation of RNA biosynthetic process
HFD79_RS09675	COG3708	Transcriptional regulator
HFD79_RS09675	COG2207	Transcriptional regulator
HFD79_RS09690	COG0730	response to heat
HFD79_RS09700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HFD79_RS09700	COG3453	Protein conserved in bacteria
HFD79_RS09710	COG3781	membrane
HFD79_RS09715	COG1063	alcohol dehydrogenase
HFD79_RS09725	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HFD79_RS09730	COG0508	dehydrogenase complex catalyzes the overall conversion of
HFD79_RS09735	COG0022	dehydrogenase e1 component
HFD79_RS09740	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HFD79_RS09745	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HFD79_RS09760	COG3706	GGDEF domain
HFD79_RS09775	COG0133	tryptophan synthase activity
HFD79_RS09785	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HFD79_RS09820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HFD79_RS09905	COG0842	Transport permease protein
HFD79_RS09910	COG0842	Transport permease protein
HFD79_RS09915	COG1131	(ABC) transporter
HFD79_RS09930	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HFD79_RS09935	COG4773	Receptor
HFD79_RS09955	COG0730	response to heat
HFD79_RS09960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HFD79_RS09980	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HFD79_RS10035	COG4264	IucA IucC family
HFD79_RS10040	COG4264	IucA IucC family
HFD79_RS10060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HFD79_RS10075	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS10080	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS10085	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HFD79_RS10090	COG2207	Transcriptional regulator
HFD79_RS10095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HFD79_RS10100	COG0776	regulation of translation
HFD79_RS10125	COG0822	iron-sulfur transferase activity
HFD79_RS10130	COG0316	Belongs to the HesB IscA family
HFD79_RS10160	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFD79_RS10190	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HFD79_RS10195	COG0702	epimerase
HFD79_RS10230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HFD79_RS10240	COG0339	signal peptide processing
HFD79_RS10290	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HFD79_RS10295	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HFD79_RS10325	COG0776	regulation of translation
HFD79_RS10390	COG0084	hydrolase, TatD family'
HFD79_RS10410	COG1663	tetraacyldisaccharide 4'-kinase activity
HFD79_RS10415	COG1132	(ABC) transporter
HFD79_RS10425	COG0811	peptide transport
HFD79_RS10430	COG1475	DNA binding
HFD79_RS10435	COG1192	Involved in chromosome partitioning
HFD79_RS10445	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HFD79_RS10460	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HFD79_RS10465	COG0191	fructose-bisphosphate aldolase activity
HFD79_RS10485	COG0424	maF-like protein
HFD79_RS10490	COG2850	peptidyl-arginine hydroxylation
HFD79_RS10500	COG0640	Transcriptional regulator
HFD79_RS10510	COG3619	membrane
HFD79_RS10515	COG3122	Protein conserved in bacteria
HFD79_RS10520	COG1132	(ABC) transporter
HFD79_RS10540	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HFD79_RS10545	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HFD79_RS10555	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HFD79_RS10555	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HFD79_RS10555	COG0506	proline dehydrogenase activity
HFD79_RS10560	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HFD79_RS10575	COG3698	Phosphodiester glycosidase
HFD79_RS10585	COG2353	YceI-like domain
HFD79_RS10595	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HFD79_RS10640	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HFD79_RS10640	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HFD79_RS10665	COG3539	Fimbrial protein
HFD79_RS10670	COG3121	Chaperone
HFD79_RS10695	COG0697	spore germination
HFD79_RS10705	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HFD79_RS10715	COG0583	DNA-binding transcription factor activity
HFD79_RS10735	COG1309	transcriptional regulator
HFD79_RS10750	COG1522	sequence-specific DNA binding
HFD79_RS10760	COG1126	abc transporter atp-binding protein
HFD79_RS10765	COG0765	amino acid transport
HFD79_RS10770	COG0765	amino acid transport
HFD79_RS10800	COG1464	Belongs to the NlpA lipoprotein family
HFD79_RS10810	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HFD79_RS10815	COG2011	ABC-type metal ion transport system permease component
HFD79_RS10820	COG0012	GTP binding
HFD79_RS10845	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HFD79_RS10885	COG0386	Belongs to the glutathione peroxidase family
HFD79_RS10895	COG0436	Aminotransferase
HFD79_RS10935	COG3634	alkyl hydroperoxide reductase activity
HFD79_RS10950	COG0583	DNA-binding transcription factor activity
HFD79_RS10955	COG0798	PFAM Bile acid sodium symporter
HFD79_RS10960	COG0640	Transcriptional regulator
HFD79_RS10975	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HFD79_RS10985	COG0583	DNA-binding transcription factor activity
HFD79_RS10995	COG1953	Uracil, thiamine, allantoin
HFD79_RS11005	COG2175	clavaminate synthase activity
HFD79_RS11010	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HFD79_RS11015	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HFD79_RS11020	COG4521	taurine ABC transporter
HFD79_RS11030	COG0477	Major facilitator Superfamily
HFD79_RS11050	COG1271	oxidase subunit
HFD79_RS11055	COG1294	oxidase, subunit
HFD79_RS11065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD79_RS11085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HFD79_RS11105	COG3052	prosthetic group binding
HFD79_RS11110	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HFD79_RS11120	COG2814	Major facilitator Superfamily
HFD79_RS11140	COG1346	cytolysis
HFD79_RS11150	COG0583	DNA-binding transcription factor activity
HFD79_RS11155	COG0625	glutathione transferase activity
HFD79_RS11160	COG0625	glutathione transferase activity
HFD79_RS11165	COG0583	DNA-binding transcription factor activity
HFD79_RS11180	COG1045	serine acetyltransferase
HFD79_RS11185	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HFD79_RS11190	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HFD79_RS11200	COG1280	lysine exporter protein (LysE YggA)
HFD79_RS11215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFD79_RS11220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFD79_RS11225	COG1126	abc transporter atp-binding protein
HFD79_RS11230	COG0765	amino acid transport
HFD79_RS11235	COG0765	amino acid transport
HFD79_RS11255	COG0784	Response regulator, receiver
HFD79_RS11255	COG2205	protein histidine kinase activity
HFD79_RS11275	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFD79_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS11345	COG0583	DNA-binding transcription factor activity
HFD79_RS11365	COG0318	PFAM AMP-dependent synthetase and ligase
HFD79_RS11370	COG1309	transcriptional regulator
HFD79_RS11375	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS11380	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HFD79_RS11385	COG1024	Enoyl-CoA hydratase
HFD79_RS11390	COG4770	biotin carboxylase activity
HFD79_RS11400	COG0583	DNA-binding transcription factor activity
HFD79_RS11415	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS11425	COG2814	Major facilitator Superfamily
HFD79_RS11435	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HFD79_RS11440	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HFD79_RS11445	COG2814	Major facilitator Superfamily
HFD79_RS11450	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS11455	COG1024	Enoyl-CoA hydratase
HFD79_RS11460	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS11465	COG1250	3-hydroxyacyl-CoA dehydrogenase
HFD79_RS11470	COG0183	Belongs to the thiolase family
HFD79_RS11480	COG2814	Major facilitator Superfamily
HFD79_RS11490	COG1024	Enoyl-CoA hydratase
HFD79_RS11505	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS11510	COG2814	Major facilitator Superfamily
HFD79_RS11515	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HFD79_RS11520	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HFD79_RS11535	COG3842	ATPase activity
HFD79_RS11540	COG1840	ABC-type Fe3 transport system, periplasmic component
HFD79_RS11550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD79_RS11555	COG1414	Transcriptional regulator
HFD79_RS11565	COG0583	DNA-binding transcription factor activity
HFD79_RS11570	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HFD79_RS11575	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS11585	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HFD79_RS11595	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS11600	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFD79_RS11605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD79_RS11610	COG2267	carboxylic ester hydrolase activity
HFD79_RS11630	COG3038	cytochrome b561
HFD79_RS11635	COG0753	catalase activity
HFD79_RS11670	COG2050	protein possibly involved in aromatic compounds catabolism
HFD79_RS11680	COG3327	negative regulation of DNA-templated transcription, initiation
HFD79_RS11685	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HFD79_RS11690	COG0183	Belongs to the thiolase family
HFD79_RS11695	COG1250	3-hydroxyacyl-CoA dehydrogenase
HFD79_RS11700	COG1024	Enoyl-CoA hydratase
HFD79_RS11705	COG1024	Enoyl-CoA hydratase
HFD79_RS11710	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HFD79_RS11715	COG2151	metal-sulfur cluster biosynthetic enzyme
HFD79_RS11720	COG3396	Phenylacetate-CoA oxygenase
HFD79_RS11725	COG3460	Phenylacetate-CoA oxygenase
HFD79_RS11730	COG3396	Phenylacetate-CoA oxygenase
HFD79_RS11735	COG2030	dehydratase
HFD79_RS11735	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS11740	COG1760	l-serine dehydratase
HFD79_RS11745	COG0531	amino acid
HFD79_RS11750	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS11765	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD79_RS11775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HFD79_RS11795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFD79_RS11805	COG0789	Transcriptional regulator
HFD79_RS11820	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HFD79_RS11835	COG2807	transmembrane transport
HFD79_RS11840	COG0590	tRNA wobble adenosine to inosine editing
HFD79_RS11955	COG1116	anion transmembrane transporter activity
HFD79_RS11960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HFD79_RS11970	COG0864	Transcriptional regulator
HFD79_RS11990	COG2249	NAD(P)H dehydrogenase (quinone) activity
HFD79_RS11995	COG0439	Biotin carboxylase
HFD79_RS12010	COG1063	alcohol dehydrogenase
HFD79_RS12020	COG1309	transcriptional regulator
HFD79_RS12040	COG0038	chloride channel
HFD79_RS12045	COG4770	biotin carboxylase activity
HFD79_RS12065	COG1914	H( )-stimulated, divalent metal cation uptake system
HFD79_RS12070	COG0583	DNA-binding transcription factor activity
HFD79_RS12085	COG3209	COG3209 Rhs family protein
HFD79_RS12090	COG3501	Rhs element vgr protein
HFD79_RS12120	COG1250	3-hydroxyacyl-CoA dehydrogenase
HFD79_RS12140	COG2814	Major facilitator Superfamily
HFD79_RS12150	COG1560	Kdo2-lipid A biosynthetic process
HFD79_RS12160	COG5006	permease, DMT superfamily
HFD79_RS12165	COG1522	sequence-specific DNA binding
HFD79_RS12180	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HFD79_RS12190	COG4122	O-methyltransferase activity
HFD79_RS12220	COG1538	Outer membrane efflux protein
HFD79_RS12230	COG1137	ATPase activity
HFD79_RS12235	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HFD79_RS12245	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HFD79_RS12250	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HFD79_RS12250	COG0517	IMP dehydrogenase activity
HFD79_RS12290	COG2814	Major facilitator Superfamily
HFD79_RS12325	COG1278	Cold shock
HFD79_RS12330	COG1280	lysine exporter protein (LysE YggA)
HFD79_RS12365	COG1570	exodeoxyribonuclease VII activity
HFD79_RS12415	COG0583	DNA-binding transcription factor activity
HFD79_RS12420	COG4638	Rieske (2fe-2S)
HFD79_RS12425	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HFD79_RS12430	COG0543	2 iron, 2 sulfur cluster binding
HFD79_RS12430	COG0633	Ferredoxin
HFD79_RS12435	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS12440	COG3135	benzoate transporter
HFD79_RS12445	COG2814	Major facilitator Superfamily
HFD79_RS12460	COG1643	Atp-dependent helicase
HFD79_RS12465	COG0450	alkyl hydroperoxide reductase
HFD79_RS12475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HFD79_RS12485	COG3634	alkyl hydroperoxide reductase activity
HFD79_RS12505	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HFD79_RS12510	COG0625	glutathione transferase activity
HFD79_RS12520	COG2885	chlorophyll binding
HFD79_RS12555	COG0542	response to heat
HFD79_RS12570	COG1765	OsmC-like protein
HFD79_RS12585	COG0667	Aldo Keto reductase
HFD79_RS12600	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HFD79_RS12610	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HFD79_RS12620	COG0527	aspartate kinase activity
HFD79_RS12630	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HFD79_RS12640	COG3038	cytochrome b561
HFD79_RS12645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HFD79_RS12650	COG2252	PERMEase
HFD79_RS12665	COG1113	amino acid transport
HFD79_RS12685	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS12705	COG0531	amino acid
HFD79_RS12715	COG1113	amino acid transport
HFD79_RS12755	COG3209	COG3209 Rhs family protein
HFD79_RS12760	COG3501	Rhs element vgr protein
HFD79_RS12785	COG4269	membrane
HFD79_RS12800	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD79_RS12800	COG1902	pentaerythritol trinitrate reductase activity
HFD79_RS12810	COG4251	negative regulation of phosphorylation
HFD79_RS12810	COG3706	GGDEF domain
HFD79_RS12810	COG2203	Gaf domain
HFD79_RS12810	COG5001	Diguanylate cyclase
HFD79_RS12820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HFD79_RS12840	COG4172	Belongs to the ABC transporter superfamily
HFD79_RS12845	COG4239	(ABC) transporter, permease
HFD79_RS12850	COG4174	ABC transporter (Permease)
HFD79_RS12860	COG1388	LysM domain
HFD79_RS12860	COG0741	lytic transglycosylase activity
HFD79_RS12860	COG0741	lytic transglycosylase activity
HFD79_RS12860	COG1388	LysM domain
HFD79_RS12865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HFD79_RS12905	COG0583	DNA-binding transcription factor activity
HFD79_RS12910	COG1279	arginine transmembrane transporter activity
HFD79_RS12930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD79_RS12935	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD79_RS12940	COG0006	proline dipeptidase activity
HFD79_RS13025	COG0741	lytic transglycosylase activity
HFD79_RS13025	COG1196	nuclear chromosome segregation
HFD79_RS13025	COG0739	heme binding
HFD79_RS13085	COG4695	Portal protein
HFD79_RS13180	COG0305	Participates in initiation and elongation during chromosome replication
HFD79_RS13195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HFD79_RS13245	COG2194	sulfuric ester hydrolase activity
HFD79_RS13290	COG0739	heme binding
HFD79_RS13615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HFD79_RS13640	COG3384	dioxygenase
HFD79_RS13650	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HFD79_RS13655	COG2878	Part of a membrane complex involved in electron transport
HFD79_RS13660	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HFD79_RS13685	COG0768	penicillin binding
HFD79_RS13690	COG0742	ribosomal rna small subunit methyltransferase
HFD79_RS13705	COG0830	nickel cation binding
HFD79_RS13715	COG0804	urea catabolic process
HFD79_RS13755	COG1253	flavin adenine dinucleotide binding
HFD79_RS13760	COG2851	Citrate transporter
HFD79_RS13810	COG1773	rubredoxin
HFD79_RS13815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HFD79_RS13825	COG0583	DNA-binding transcription factor activity
HFD79_RS13850	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HFD79_RS13855	COG4181	ATPase activity
HFD79_RS13900	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HFD79_RS13920	COG0306	phosphate transporter
HFD79_RS13930	COG3958	Transketolase
HFD79_RS13935	COG3959	Transketolase, thiamine diphosphate binding domain
HFD79_RS13940	COG2271	Major facilitator Superfamily
HFD79_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS13950	COG0583	DNA-binding transcription factor activity
HFD79_RS13965	COG2223	nitrite transmembrane transporter activity
HFD79_RS13970	COG2207	Transcriptional regulator
HFD79_RS13975	COG2066	Belongs to the glutaminase family
HFD79_RS13980	COG0242	peptide deformylase activity
HFD79_RS13985	COG0477	Major facilitator Superfamily
HFD79_RS13995	COG0028	Belongs to the TPP enzyme family
HFD79_RS14010	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS14015	COG2267	carboxylic ester hydrolase activity
HFD79_RS14025	COG2271	Major facilitator Superfamily
HFD79_RS14030	COG0446	pyridine nucleotide-disulphide oxidoreductase
HFD79_RS14040	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS14060	COG1414	Transcriptional regulator
HFD79_RS14075	COG1024	Enoyl-CoA hydratase
HFD79_RS14085	COG1215	transferase activity, transferring glycosyl groups
HFD79_RS14090	COG1649	PFAM Uncharacterised BCR, COG1649
HFD79_RS14090	COG0726	polysaccharide deacetylase
HFD79_RS14100	COG4681	YaeQ
HFD79_RS14110	COG0523	cobalamin synthesis protein
HFD79_RS14120	COG1607	acyl-coa hydrolase
HFD79_RS14130	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD79_RS14135	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HFD79_RS14140	COG1309	transcriptional regulator
HFD79_RS14165	COG2040	homocysteine
HFD79_RS14170	COG0531	amino acid
HFD79_RS14195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFD79_RS14200	COG0477	Major facilitator Superfamily
HFD79_RS14250	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFD79_RS14335	COG0592	DNA-directed DNA polymerase activity
HFD79_RS14375	COG2026	Addiction module toxin, RelE StbE family
HFD79_RS14570	COG1484	DNA-dependent DNA replication
HFD79_RS14710	COG0405	Gamma-glutamyltransferase
HFD79_RS14715	COG2814	Major facilitator Superfamily
HFD79_RS14725	COG2050	protein possibly involved in aromatic compounds catabolism
HFD79_RS14740	COG1090	epimerase
HFD79_RS14760	COG0420	3'-5' exonuclease activity
HFD79_RS14785	COG0735	belongs to the Fur family
HFD79_RS14790	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HFD79_RS14810	COG0121	glutamine amidotransferase
HFD79_RS14825	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFD79_RS14835	COG0210	DNA helicase
HFD79_RS14840	COG2885	chlorophyll binding
HFD79_RS14845	COG0204	Acyl-transferase
HFD79_RS14860	COG2894	cell division
HFD79_RS14880	COG1280	lysine exporter protein (LysE YggA)
HFD79_RS14885	COG1674	ftsk spoiiie
HFD79_RS14885	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HFD79_RS14890	COG0492	ferredoxin-NADP+ reductase activity
HFD79_RS14895	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HFD79_RS14905	COG0456	acetyltransferase
HFD79_RS14965	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HFD79_RS14965	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HFD79_RS14985	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS15005	COG0473	3-isopropylmalate dehydrogenase activity
HFD79_RS15010	COG0583	DNA-binding transcription factor activity
HFD79_RS15030	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HFD79_RS15055	COG0564	pseudouridine synthase activity
HFD79_RS15065	COG0358	DNA primase activity
HFD79_RS15080	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HFD79_RS15110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HFD79_RS15140	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HFD79_RS15150	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HFD79_RS15150	COG0351	phosphomethylpyrimidine kinase
HFD79_RS15150	COG0352	thiamine-phosphate diphosphorylase activity
HFD79_RS15160	COG1652	LysM domain
HFD79_RS15185	COG1399	metal-binding, possibly nucleic acid-binding protein
HFD79_RS15190	COG3101	peptidyl-lysine hydroxylation
HFD79_RS15195	COG0009	L-threonylcarbamoyladenylate synthase
HFD79_RS15200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HFD79_RS15205	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HFD79_RS15220	COG4106	trans-aconitate 2-methyltransferase activity
HFD79_RS15235	COG2226	methyltransferase
HFD79_RS15235	COG0596	Alpha beta hydrolase
HFD79_RS15235	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFD79_RS15240	COG1877	trehalose-phosphatase activity
HFD79_RS15245	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HFD79_RS15250	COG2223	nitrite transmembrane transporter activity
HFD79_RS15270	COG1196	nuclear chromosome segregation
HFD79_RS15280	COG0730	response to heat
HFD79_RS15295	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HFD79_RS15305	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFD79_RS15355	COG0489	protein tyrosine kinase activity
HFD79_RS15365	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFD79_RS15365	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFD79_RS15395	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HFD79_RS15400	COG2081	HI0933 family
HFD79_RS15410	COG0668	transmembrane transport
HFD79_RS15430	COG0583	DNA-binding transcription factor activity
HFD79_RS15450	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HFD79_RS15455	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HFD79_RS15485	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HFD79_RS15520	COG2205	protein histidine kinase activity
HFD79_RS15525	COG0745	RESPONSE REGULATOR receiver
HFD79_RS15545	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFD79_RS15555	COG2205	protein histidine kinase activity
HFD79_RS15625	COG4993	Dehydrogenase
HFD79_RS15645	COG0384	phenazine biosynthesis protein PhzF
HFD79_RS15665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HFD79_RS15680	COG0583	DNA-binding transcription factor activity
HFD79_RS15700	COG1473	amidohydrolase
HFD79_RS15710	COG0583	DNA-binding transcription factor activity
HFD79_RS15725	COG0583	DNA-binding transcription factor activity
HFD79_RS15730	COG1053	succinate dehydrogenase
HFD79_RS15740	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HFD79_RS15745	COG2814	Major facilitator Superfamily
HFD79_RS15750	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS15755	COG0583	DNA-binding transcription factor activity
HFD79_RS15760	COG1063	alcohol dehydrogenase
HFD79_RS15790	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HFD79_RS15795	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HFD79_RS15800	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFD79_RS15815	COG3667	copper resistance
HFD79_RS15820	COG2132	Multicopper oxidase
HFD79_RS15830	COG0561	phosphatase activity
HFD79_RS15835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HFD79_RS15860	COG1214	PFAM Peptidase M22, glycoprotease
HFD79_RS15910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HFD79_RS15920	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HFD79_RS15925	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HFD79_RS15930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HFD79_RS15990	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HFD79_RS16000	COG1846	Transcriptional regulator
HFD79_RS16005	COG1764	response to oxidative stress
HFD79_RS16045	COG0037	tRNA processing
HFD79_RS16055	COG0248	Ppx GppA phosphatase
HFD79_RS16085	COG0072	phenylalanine-tRNA ligase activity
HFD79_RS16125	COG1238	metal cluster binding
HFD79_RS16130	COG0625	glutathione transferase activity
HFD79_RS16145	COG0318	PFAM AMP-dependent synthetase and ligase
HFD79_RS16150	COG3028	Belongs to the UPF0307 family
HFD79_RS16155	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HFD79_RS16175	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HFD79_RS16180	COG0617	tRNA 3'-terminal CCA addition
HFD79_RS16185	COG1555	photosystem II stabilization
HFD79_RS16190	COG3956	TIGRFAM MazG family protein
HFD79_RS16200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HFD79_RS16220	COG0784	Response regulator, receiver
HFD79_RS16220	COG2205	protein histidine kinase activity
HFD79_RS16220	COG5002	protein histidine kinase activity
HFD79_RS16225	COG1024	Enoyl-CoA hydratase
HFD79_RS16230	COG2084	Dehydrogenase
HFD79_RS16235	COG3622	Belongs to the hyi family
HFD79_RS16265	COG0697	spore germination
HFD79_RS16275	COG2814	Major facilitator Superfamily
HFD79_RS16280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HFD79_RS16290	COG0583	DNA-binding transcription factor activity
HFD79_RS16300	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HFD79_RS16315	COG0084	hydrolase, TatD family'
HFD79_RS16330	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HFD79_RS16360	COG0440	acetolactate synthase activity
HFD79_RS16365	COG0028	Belongs to the TPP enzyme family
HFD79_RS16390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HFD79_RS16395	COG0577	efflux transmembrane transporter activity
HFD79_RS16395	COG1136	(ABC) transporter
HFD79_RS16400	COG1538	Outer membrane efflux protein
HFD79_RS16415	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HFD79_RS16420	COG1162	GTPase activity
HFD79_RS16430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HFD79_RS16450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HFD79_RS16455	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS16495	COG2986	histidine ammonia-lyase
HFD79_RS16510	COG0318	PFAM AMP-dependent synthetase and ligase
HFD79_RS16520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFD79_RS16565	COG1426	Protein conserved in bacteria
HFD79_RS16600	COG0793	Belongs to the peptidase S41A family
HFD79_RS16615	COG2267	carboxylic ester hydrolase activity
HFD79_RS16625	COG1012	belongs to the aldehyde dehydrogenase family
HFD79_RS16630	COG3265	gluconokinase activity
HFD79_RS16640	COG0800	Aldolase
HFD79_RS16650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HFD79_RS16655	COG0280	phosphate acetyltransferase
HFD79_RS16655	COG0857	belongs to the CobB CobQ family
HFD79_RS16660	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HFD79_RS16660	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HFD79_RS16680	COG0740	serine-type endopeptidase activity
HFD79_RS16690	COG4774	siderophore transport
HFD79_RS16700	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HFD79_RS16710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HFD79_RS16710	COG2813	Specifically methylates the guanine in position
HFD79_RS16810	COG0788	formyltetrahydrofolate deformylase activity
HFD79_RS16835	COG4651	solute:proton antiporter activity
HFD79_RS16835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HFD79_RS16855	COG0724	RNA recognition motif
HFD79_RS16860	COG0210	DNA helicase
HFD79_RS16885	COG1733	regulation of RNA biosynthetic process
HFD79_RS16895	COG2900	Belongs to the SlyX family
HFD79_RS16905	COG1280	lysine exporter protein (LysE YggA)
HFD79_RS16910	COG1560	Kdo2-lipid A biosynthetic process
HFD79_RS16920	COG1301	dicarboxylic acid transport
HFD79_RS16975	COG0473	3-isopropylmalate dehydrogenase activity
HFD79_RS17040	COG0583	DNA-binding transcription factor activity
HFD79_RS17050	COG0625	glutathione transferase activity
HFD79_RS17055	COG2378	regulation of single-species biofilm formation
HFD79_RS17060	COG0546	phosphoglycolate phosphatase activity
HFD79_RS17075	COG1530	ribonuclease E activity
HFD79_RS17080	COG0318	PFAM AMP-dependent synthetase and ligase
HFD79_RS17095	COG0583	DNA-binding transcription factor activity
HFD79_RS17100	COG4221	oxidoreductase activity
HFD79_RS17105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HFD79_RS17115	COG0534	Mate efflux family protein
HFD79_RS17130	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HFD79_RS17170	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HFD79_RS17175	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HFD79_RS17190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HFD79_RS17200	COG0644	oxidoreductase
HFD79_RS17200	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HFD79_RS17205	COG0425	Belongs to the sulfur carrier protein TusA family
HFD79_RS17210	COG4535	Mg2 and Co2 transporter CorC
HFD79_RS17220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HFD79_RS17240	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HFD79_RS17245	COG0475	glutathione-regulated potassium exporter activity
HFD79_RS17245	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HFD79_RS17250	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HFD79_RS17260	COG0484	heat shock protein binding
HFD79_RS17265	COG0789	Transcriptional regulator
HFD79_RS17270	COG0598	Magnesium transport protein CorA
HFD79_RS17290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HFD79_RS17295	COG1074	ATP-dependent DNA helicase activity
HFD79_RS17300	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HFD79_RS17320	COG2226	methyltransferase
HFD79_RS17335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HFD79_RS17340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HFD79_RS17355	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HFD79_RS17355	COG2111	Na H antiporter
HFD79_RS17360	COG1006	Multisubunit Na H antiporter MnhC subunit
HFD79_RS17365	COG0651	ATP synthesis coupled electron transport
HFD79_RS17375	COG2212	antiporter activity
HFD79_RS17395	COG0195	Participates in both transcription termination and antitermination
HFD79_RS17445	COG0237	dephospho-CoA kinase activity
HFD79_RS17455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HFD79_RS17470	COG0497	DNA recombination
HFD79_RS17480	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HFD79_RS17510	COG2169	Transcriptional regulator
HFD79_RS17510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HFD79_RS17515	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HFD79_RS17580	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HFD79_RS17595	COG0326	Molecular chaperone. Has ATPase activity
HFD79_RS17610	COG2056	Na+-H+ antiporter family
HFD79_RS17615	COG0596	Alpha beta hydrolase
HFD79_RS17710	COG0546	phosphoglycolate phosphatase activity
HFD79_RS17715	COG1716	ATPase activity
HFD79_RS17760	COG0181	hydroxymethylbilane synthase activity
HFD79_RS17770	COG3275	phosphorelay sensor kinase activity
HFD79_RS17790	COG1538	Outer membrane efflux protein
HFD79_RS17795	COG0697	spore germination
HFD79_RS17820	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HFD79_RS17825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HFD79_RS17830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HFD79_RS17835	COG0772	Belongs to the SEDS family
HFD79_RS17860	COG4974	Belongs to the 'phage' integrase family
HFD79_RS17865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HFD79_RS17875	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HFD79_RS17885	COG2197	response regulator
HFD79_RS17900	COG0793	Belongs to the peptidase S41A family
HFD79_RS17905	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HFD79_RS17910	COG0795	lipopolysaccharide-transporting ATPase activity
HFD79_RS17950	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFD79_RS17950	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HFD79_RS17960	COG0004	ammonium transporteR
HFD79_RS17965	COG0347	Belongs to the P(II) protein family
HFD79_RS17975	COG0606	chelatase, subunit chli
HFD79_RS18045	COG0659	secondary active sulfate transmembrane transporter activity
HFD79_RS18050	COG0589	response to stress
HFD79_RS18095	COG0606	chelatase, subunit chli
HFD79_RS18100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HFD79_RS18110	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HFD79_RS18125	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HFD79_RS18140	COG0318	PFAM AMP-dependent synthetase and ligase
HFD79_RS18150	COG0477	Major facilitator Superfamily
HFD79_RS18155	COG2860	membrane
HFD79_RS18165	COG1253	flavin adenine dinucleotide binding
HFD79_RS18185	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HFD79_RS18220	COG0655	NAD(P)H dehydrogenase (quinone) activity
HFD79_RS18230	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HFD79_RS18265	COG1309	transcriptional regulator
HFD79_RS18300	COG0758	DNA mediated transformation
HFD79_RS18310	COG0697	spore germination
HFD79_RS18315	COG1309	transcriptional regulator
HFD79_RS18330	COG0386	Belongs to the glutathione peroxidase family
HFD79_RS18395	COG1121	(ABC) transporter
HFD79_RS18400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HFD79_RS18405	COG1280	lysine exporter protein (LysE YggA)
HFD79_RS18410	COG2837	iron assimilation
HFD79_RS18420	COG0281	malic enzyme
HFD79_RS18465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HFD79_RS18465	COG0519	Catalyzes the synthesis of GMP from XMP
HFD79_RS18470	COG4399	Belongs to the UPF0754 family
HFD79_RS18475	COG2259	Doxx family
HFD79_RS18480	COG0586	Pfam SNARE associated Golgi protein
HFD79_RS18495	COG1192	Involved in chromosome partitioning
HFD79_RS18505	COG0271	Belongs to the BolA IbaG family
HFD79_RS18525	COG2267	carboxylic ester hydrolase activity
HFD79_RS18545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HFD79_RS18545	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HFD79_RS18545	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HFD79_RS18545	COG3321	synthase
HFD79_RS18550	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS18560	COG2197	response regulator
HFD79_RS18570	COG3916	Acyl-homoserine-lactone synthase
HFD79_RS18575	COG0477	Major facilitator Superfamily
HFD79_RS18580	COG1024	Enoyl-CoA hydratase
HFD79_RS18585	COG1024	Enoyl-CoA hydratase
HFD79_RS18590	COG1960	acyl-CoA dehydrogenase activity
HFD79_RS18595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HFD79_RS18615	COG1113	amino acid transport
HFD79_RS18620	COG1113	amino acid transport
HFD79_RS18625	COG0251	oxidation-reduction process
HFD79_RS18665	COG0564	pseudouridine synthase activity
HFD79_RS18725	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HFD79_RS18740	COG1802	Transcriptional regulator
HFD79_RS18750	COG1448	Aminotransferase
HFD79_RS18755	COG0277	FAD linked oxidase domain protein
HFD79_RS18765	COG2186	Transcriptional regulator
HFD79_RS18775	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HFD79_RS18785	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HFD79_RS18800	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HFD79_RS18805	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HFD79_RS18825	COG1215	transferase activity, transferring glycosyl groups
HFD79_RS18835	COG0438	transferase activity, transferring glycosyl groups
HFD79_RS18860	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HFD79_RS18865	COG1596	polysaccharide export
HFD79_RS18890	COG0728	peptidoglycan biosynthetic process
HFD79_RS18895	COG3023	N-Acetylmuramoyl-L-alanine amidase
HFD79_RS18950	COG0546	phosphoglycolate phosphatase activity
HFD79_RS18955	COG1028	Short-chain dehydrogenase reductase Sdr
HFD79_RS18975	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HFD79_RS18980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HFD79_RS18985	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HFD79_RS18990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HFD79_RS18995	COG1116	anion transmembrane transporter activity
HFD79_RS19000	COG1309	transcriptional regulator
HFD79_RS19005	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HFD79_RS19015	COG0196	riboflavin kinase activity
HFD79_RS19020	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HFD79_RS19030	COG1047	Peptidyl-prolyl cis-trans
HFD79_RS19070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HFD79_RS19125	COG2951	lytic endotransglycosylase activity
HFD79_RS19130	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HFD79_RS19145	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HFD79_RS19155	COG0671	phosphoesterase, PA-phosphatase related
HFD79_RS19160	COG0861	Integral membrane protein TerC family
HFD79_RS19170	COG0754	glutathionylspermidine amidase activity
HFD79_RS19180	COG0402	S-adenosylhomocysteine deaminase activity
HFD79_RS19195	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HFD79_RS19200	COG1230	cation diffusion facilitator family transporter
HFD79_RS19215	COG0706	membrane insertase activity
HFD79_RS19290	COG0358	DNA primase activity
HFD79_RS19345	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HFD79_RS19390	COG0587	DNA-directed DNA polymerase activity
HFD79_RS19405	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFD79_RS19405	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
HFD79_RS19455	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFD79_RS19455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HFD79_RS19460	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HFD79_RS19500	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HFD79_RS19540	COG2130	NADP-dependent
HFD79_RS19550	COG1309	transcriptional regulator
HFD79_RS19560	COG1902	pentaerythritol trinitrate reductase activity
HFD79_RS19570	COG1979	alcohol dehydrogenase
HFD79_RS19580	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HFD79_RS19605	COG1063	alcohol dehydrogenase
HFD79_RS19685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HFD79_RS19705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system