locus-tag	class	description
DU202_RS00005	COG0488	(ABC) transporter
DU202_RS00010	COG0586	Pfam SNARE associated Golgi protein
DU202_RS00020	COG0187	DNA topoisomerase II activity
DU202_RS00030	COG0592	DNA-directed DNA polymerase activity
DU202_RS00055	COG0706	membrane insertase activity
DU202_RS00070	COG1230	cation diffusion facilitator family transporter
DU202_RS00075	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DU202_RS00095	COG0402	S-adenosylhomocysteine deaminase activity
DU202_RS00105	COG0754	glutathionylspermidine amidase activity
DU202_RS00115	COG0861	Integral membrane protein TerC family
DU202_RS00120	COG0671	phosphoesterase, PA-phosphatase related
DU202_RS00130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DU202_RS00145	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DU202_RS00150	COG2951	lytic endotransglycosylase activity
DU202_RS00180	COG0583	DNA-binding transcription factor activity
DU202_RS00200	COG0657	acetylesterase activity
DU202_RS00205	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DU202_RS00245	COG1047	Peptidyl-prolyl cis-trans
DU202_RS00255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DU202_RS00260	COG0196	riboflavin kinase activity
DU202_RS00270	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DU202_RS00275	COG1309	transcriptional regulator
DU202_RS00280	COG1116	anion transmembrane transporter activity
DU202_RS00285	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DU202_RS00290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DU202_RS00295	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DU202_RS00300	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DU202_RS00320	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS00325	COG0546	phosphoglycolate phosphatase activity
DU202_RS00380	COG3023	N-Acetylmuramoyl-L-alanine amidase
DU202_RS00385	COG0728	peptidoglycan biosynthetic process
DU202_RS00415	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DU202_RS00420	COG1086	Polysaccharide biosynthesis protein
DU202_RS00425	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DU202_RS00430	COG1083	cytidylyl-transferase
DU202_RS00445	COG2089	acid synthase
DU202_RS00450	COG2244	polysaccharide biosynthetic process
DU202_RS00470	COG1216	Glycosyl transferase, family 2
DU202_RS00475	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DU202_RS00480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DU202_RS00495	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DU202_RS00500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DU202_RS00510	COG2186	Transcriptional regulator
DU202_RS00520	COG0277	FAD linked oxidase domain protein
DU202_RS00525	COG1448	Aminotransferase
DU202_RS00530	COG1802	Transcriptional regulator
DU202_RS00545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DU202_RS00560	COG1051	belongs to the nudix hydrolase family
DU202_RS00600	COG0564	pseudouridine synthase activity
DU202_RS00640	COG0251	oxidation-reduction process
DU202_RS00645	COG1113	amino acid transport
DU202_RS00650	COG1113	amino acid transport
DU202_RS00670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DU202_RS00675	COG1960	acyl-CoA dehydrogenase activity
DU202_RS00680	COG1024	Enoyl-CoA hydratase
DU202_RS00685	COG1024	Enoyl-CoA hydratase
DU202_RS00690	COG0477	Major facilitator Superfamily
DU202_RS00695	COG3916	Acyl-homoserine-lactone synthase
DU202_RS00710	COG2197	response regulator
DU202_RS00725	COG1960	acyl-CoA dehydrogenase activity
DU202_RS00730	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DU202_RS00730	COG3321	synthase
DU202_RS00730	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DU202_RS00730	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DU202_RS00765	COG2267	carboxylic ester hydrolase activity
DU202_RS00785	COG0271	Belongs to the BolA IbaG family
DU202_RS00795	COG1192	Involved in chromosome partitioning
DU202_RS00810	COG0586	Pfam SNARE associated Golgi protein
DU202_RS00815	COG2259	Doxx family
DU202_RS00820	COG4399	Belongs to the UPF0754 family
DU202_RS00825	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DU202_RS00825	COG0519	Catalyzes the synthesis of GMP from XMP
DU202_RS00870	COG0281	malic enzyme
DU202_RS00880	COG2837	iron assimilation
DU202_RS00885	COG1280	lysine exporter protein (LysE YggA)
DU202_RS00890	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DU202_RS00895	COG1121	(ABC) transporter
DU202_RS00960	COG0386	Belongs to the glutathione peroxidase family
DU202_RS00975	COG1309	transcriptional regulator
DU202_RS00980	COG0697	spore germination
DU202_RS00990	COG0758	DNA mediated transformation
DU202_RS01035	COG1309	transcriptional regulator
DU202_RS01070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DU202_RS01080	COG0655	NAD(P)H dehydrogenase (quinone) activity
DU202_RS01115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DU202_RS01125	COG2814	Major facilitator Superfamily
DU202_RS01135	COG1253	flavin adenine dinucleotide binding
DU202_RS01145	COG2860	membrane
DU202_RS01150	COG0477	Major facilitator Superfamily
DU202_RS01160	COG0318	PFAM AMP-dependent synthetase and ligase
DU202_RS01175	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DU202_RS01190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DU202_RS01200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DU202_RS01205	COG0606	chelatase, subunit chli
DU202_RS01235	COG0589	response to stress
DU202_RS01240	COG0659	secondary active sulfate transmembrane transporter activity
DU202_RS01290	COG0606	chelatase, subunit chli
DU202_RS01300	COG0347	Belongs to the P(II) protein family
DU202_RS01305	COG0004	ammonium transporteR
DU202_RS01315	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DU202_RS01315	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DU202_RS01355	COG0795	lipopolysaccharide-transporting ATPase activity
DU202_RS01360	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DU202_RS01365	COG0793	Belongs to the peptidase S41A family
DU202_RS01380	COG2197	response regulator
DU202_RS01390	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DU202_RS01400	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DU202_RS01430	COG0772	Belongs to the SEDS family
DU202_RS01435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DU202_RS01440	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DU202_RS01445	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DU202_RS01470	COG0697	spore germination
DU202_RS01475	COG1538	Outer membrane efflux protein
DU202_RS01495	COG3275	phosphorelay sensor kinase activity
DU202_RS01505	COG0181	hydroxymethylbilane synthase activity
DU202_RS01550	COG1716	ATPase activity
DU202_RS01555	COG0546	phosphoglycolate phosphatase activity
DU202_RS01650	COG0596	Alpha beta hydrolase
DU202_RS01655	COG2056	Na+-H+ antiporter family
DU202_RS01670	COG0326	Molecular chaperone. Has ATPase activity
DU202_RS01685	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DU202_RS01750	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DU202_RS01755	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DU202_RS01755	COG2169	Transcriptional regulator
DU202_RS01785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DU202_RS01795	COG0497	DNA recombination
DU202_RS01810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DU202_RS01820	COG0237	dephospho-CoA kinase activity
DU202_RS01870	COG0195	Participates in both transcription termination and antitermination
DU202_RS01885	COG1320	monovalent cation:proton antiporter activity
DU202_RS01890	COG2212	antiporter activity
DU202_RS01895	COG1863	multisubunit Na H antiporter MnhE subunit
DU202_RS01900	COG0651	ATP synthesis coupled electron transport
DU202_RS01905	COG1006	Multisubunit Na H antiporter MnhC subunit
DU202_RS01910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DU202_RS01910	COG2111	Na H antiporter
DU202_RS01925	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DU202_RS01930	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DU202_RS01945	COG2226	methyltransferase
DU202_RS01965	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DU202_RS01970	COG1074	ATP-dependent DNA helicase activity
DU202_RS01975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DU202_RS01980	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DU202_RS01995	COG0598	Magnesium transport protein CorA
DU202_RS02000	COG0789	Transcriptional regulator
DU202_RS02005	COG0484	heat shock protein binding
DU202_RS02015	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DU202_RS02020	COG0475	glutathione-regulated potassium exporter activity
DU202_RS02020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DU202_RS02025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DU202_RS02050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DU202_RS02060	COG4535	Mg2 and Co2 transporter CorC
DU202_RS02065	COG0425	Belongs to the sulfur carrier protein TusA family
DU202_RS02070	COG0644	oxidoreductase
DU202_RS02070	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DU202_RS02080	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DU202_RS02095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DU202_RS02100	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DU202_RS02135	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DU202_RS02150	COG0534	Mate efflux family protein
DU202_RS02165	COG0534	Mate efflux family protein
DU202_RS02175	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DU202_RS02180	COG4221	oxidoreductase activity
DU202_RS02185	COG0583	DNA-binding transcription factor activity
DU202_RS02200	COG0318	PFAM AMP-dependent synthetase and ligase
DU202_RS02205	COG1530	ribonuclease E activity
DU202_RS02215	COG0546	phosphoglycolate phosphatase activity
DU202_RS02220	COG2378	regulation of single-species biofilm formation
DU202_RS02225	COG0625	glutathione transferase activity
DU202_RS02240	COG0583	DNA-binding transcription factor activity
DU202_RS02305	COG0473	3-isopropylmalate dehydrogenase activity
DU202_RS02360	COG1301	dicarboxylic acid transport
DU202_RS02370	COG1560	Kdo2-lipid A biosynthetic process
DU202_RS02375	COG1280	lysine exporter protein (LysE YggA)
DU202_RS02380	COG0488	(ABC) transporter
DU202_RS02385	COG2900	Belongs to the SlyX family
DU202_RS02395	COG1733	regulation of RNA biosynthetic process
DU202_RS02420	COG0210	DNA helicase
DU202_RS02425	COG0724	RNA recognition motif
DU202_RS02445	COG4651	solute:proton antiporter activity
DU202_RS02445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DU202_RS02470	COG0788	formyltetrahydrofolate deformylase activity
DU202_RS02570	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DU202_RS02570	COG2813	Specifically methylates the guanine in position
DU202_RS02580	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DU202_RS02590	COG4774	siderophore transport
DU202_RS02600	COG0740	serine-type endopeptidase activity
DU202_RS02620	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DU202_RS02620	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DU202_RS02625	COG0857	belongs to the CobB CobQ family
DU202_RS02625	COG0280	phosphate acetyltransferase
DU202_RS02630	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DU202_RS02640	COG0800	Aldolase
DU202_RS02650	COG3265	gluconokinase activity
DU202_RS02655	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS02665	COG2267	carboxylic ester hydrolase activity
DU202_RS02680	COG0793	Belongs to the peptidase S41A family
DU202_RS02715	COG1426	Protein conserved in bacteria
DU202_RS02760	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DU202_RS02770	COG0318	PFAM AMP-dependent synthetase and ligase
DU202_RS02785	COG2986	histidine ammonia-lyase
DU202_RS02825	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS02830	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DU202_RS02850	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DU202_RS02860	COG1162	GTPase activity
DU202_RS02865	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DU202_RS02880	COG1538	Outer membrane efflux protein
DU202_RS02885	COG1136	(ABC) transporter
DU202_RS02885	COG0577	efflux transmembrane transporter activity
DU202_RS02890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DU202_RS02915	COG0028	Belongs to the TPP enzyme family
DU202_RS02920	COG0440	acetolactate synthase activity
DU202_RS02955	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DU202_RS02970	COG0084	hydrolase, TatD family'
DU202_RS02985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DU202_RS02990	COG0583	DNA-binding transcription factor activity
DU202_RS03000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DU202_RS03015	COG2814	Major facilitator Superfamily
DU202_RS03025	COG0697	spore germination
DU202_RS03055	COG3622	Belongs to the hyi family
DU202_RS03060	COG2084	Dehydrogenase
DU202_RS03065	COG1024	Enoyl-CoA hydratase
DU202_RS03070	COG2205	protein histidine kinase activity
DU202_RS03070	COG5002	protein histidine kinase activity
DU202_RS03070	COG0784	Response regulator, receiver
DU202_RS03090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DU202_RS03100	COG3956	TIGRFAM MazG family protein
DU202_RS03105	COG1555	photosystem II stabilization
DU202_RS03110	COG0617	tRNA 3'-terminal CCA addition
DU202_RS03115	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DU202_RS03135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DU202_RS03140	COG3028	Belongs to the UPF0307 family
DU202_RS03145	COG0318	PFAM AMP-dependent synthetase and ligase
DU202_RS03160	COG0625	glutathione transferase activity
DU202_RS03165	COG1238	metal cluster binding
DU202_RS03205	COG0072	phenylalanine-tRNA ligase activity
DU202_RS03230	COG0248	Ppx GppA phosphatase
DU202_RS03240	COG0037	tRNA processing
DU202_RS03280	COG1764	response to oxidative stress
DU202_RS03285	COG1846	Transcriptional regulator
DU202_RS03295	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DU202_RS03355	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DU202_RS03360	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DU202_RS03365	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DU202_RS03375	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DU202_RS03435	COG1214	PFAM Peptidase M22, glycoprotease
DU202_RS03470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DU202_RS03485	COG0561	phosphatase activity
DU202_RS03495	COG2132	Multicopper oxidase
DU202_RS03500	COG3667	copper resistance
DU202_RS03515	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DU202_RS03520	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DU202_RS03525	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DU202_RS03555	COG1063	alcohol dehydrogenase
DU202_RS03560	COG0583	DNA-binding transcription factor activity
DU202_RS03565	COG1960	acyl-CoA dehydrogenase activity
DU202_RS03570	COG2814	Major facilitator Superfamily
DU202_RS03575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DU202_RS03585	COG1053	succinate dehydrogenase
DU202_RS03590	COG0583	DNA-binding transcription factor activity
DU202_RS03605	COG0583	DNA-binding transcription factor activity
DU202_RS03635	COG0583	DNA-binding transcription factor activity
DU202_RS03650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DU202_RS03680	COG0384	phenazine biosynthesis protein PhzF
DU202_RS03705	COG4993	Dehydrogenase
DU202_RS03810	COG2205	protein histidine kinase activity
DU202_RS03830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DU202_RS03850	COG0745	RESPONSE REGULATOR receiver
DU202_RS03890	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DU202_RS03920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DU202_RS03925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DU202_RS03945	COG0583	DNA-binding transcription factor activity
DU202_RS03965	COG0668	transmembrane transport
DU202_RS03975	COG2081	HI0933 family
DU202_RS03980	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DU202_RS04010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DU202_RS04010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DU202_RS04020	COG0489	protein tyrosine kinase activity
DU202_RS04070	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DU202_RS04080	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DU202_RS04095	COG0730	response to heat
DU202_RS04105	COG1196	nuclear chromosome segregation
DU202_RS04125	COG2223	nitrite transmembrane transporter activity
DU202_RS04130	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DU202_RS04140	COG1877	trehalose-phosphatase activity
DU202_RS04145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DU202_RS04145	COG2226	methyltransferase
DU202_RS04145	COG0596	Alpha beta hydrolase
DU202_RS04160	COG4106	trans-aconitate 2-methyltransferase activity
DU202_RS04175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DU202_RS04180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DU202_RS04185	COG0009	L-threonylcarbamoyladenylate synthase
DU202_RS04190	COG3101	peptidyl-lysine hydroxylation
DU202_RS04195	COG1399	metal-binding, possibly nucleic acid-binding protein
DU202_RS04220	COG1652	LysM domain
DU202_RS04225	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DU202_RS04225	COG0352	thiamine-phosphate diphosphorylase activity
DU202_RS04225	COG0351	phosphomethylpyrimidine kinase
DU202_RS04235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DU202_RS04265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DU202_RS04295	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DU202_RS04310	COG0358	DNA primase activity
DU202_RS04320	COG0564	pseudouridine synthase activity
DU202_RS04345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DU202_RS04365	COG0583	DNA-binding transcription factor activity
DU202_RS04370	COG0473	3-isopropylmalate dehydrogenase activity
DU202_RS04390	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS04410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DU202_RS04410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DU202_RS04425	COG1981	membrane
DU202_RS04470	COG0456	acetyltransferase
DU202_RS04480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DU202_RS04485	COG0492	ferredoxin-NADP+ reductase activity
DU202_RS04490	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DU202_RS04490	COG1674	ftsk spoiiie
DU202_RS04495	COG1280	lysine exporter protein (LysE YggA)
DU202_RS04520	COG2894	cell division
DU202_RS04535	COG0204	Acyl-transferase
DU202_RS04540	COG2885	chlorophyll binding
DU202_RS04545	COG0210	DNA helicase
DU202_RS04555	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DU202_RS04570	COG0121	glutamine amidotransferase
DU202_RS04580	COG0121	glutamine amidotransferase
DU202_RS04600	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DU202_RS04605	COG0735	belongs to the Fur family
DU202_RS04630	COG0420	3'-5' exonuclease activity
DU202_RS04650	COG1090	epimerase
DU202_RS04665	COG2050	protein possibly involved in aromatic compounds catabolism
DU202_RS04675	COG2814	Major facilitator Superfamily
DU202_RS04680	COG0405	Gamma-glutamyltransferase
DU202_RS04715	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DU202_RS04825	COG1484	DNA-dependent DNA replication
DU202_RS05045	COG2026	Addiction module toxin, RelE StbE family
DU202_RS05085	COG0592	DNA-directed DNA polymerase activity
DU202_RS05165	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DU202_RS05230	COG0477	Major facilitator Superfamily
DU202_RS05235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DU202_RS05260	COG0531	amino acid
DU202_RS05265	COG2040	homocysteine
DU202_RS05290	COG1309	transcriptional regulator
DU202_RS05295	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DU202_RS05300	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DU202_RS05310	COG1607	acyl-coa hydrolase
DU202_RS05320	COG0523	cobalamin synthesis protein
DU202_RS05335	COG1301	dicarboxylic acid transport
DU202_RS05340	COG4681	YaeQ
DU202_RS05350	COG1649	PFAM Uncharacterised BCR, COG1649
DU202_RS05350	COG0726	polysaccharide deacetylase
DU202_RS05355	COG1215	transferase activity, transferring glycosyl groups
DU202_RS05365	COG1024	Enoyl-CoA hydratase
DU202_RS05385	COG1414	Transcriptional regulator
DU202_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS05415	COG0446	pyridine nucleotide-disulphide oxidoreductase
DU202_RS05420	COG2271	Major facilitator Superfamily
DU202_RS05430	COG2267	carboxylic ester hydrolase activity
DU202_RS05435	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS05450	COG0028	Belongs to the TPP enzyme family
DU202_RS05460	COG0477	Major facilitator Superfamily
DU202_RS05465	COG0242	peptide deformylase activity
DU202_RS05470	COG2066	Belongs to the glutaminase family
DU202_RS05475	COG2207	Transcriptional regulator
DU202_RS05480	COG2223	nitrite transmembrane transporter activity
DU202_RS05495	COG0583	DNA-binding transcription factor activity
DU202_RS05500	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS05505	COG2271	Major facilitator Superfamily
DU202_RS05510	COG3959	Transketolase, thiamine diphosphate binding domain
DU202_RS05515	COG3958	Transketolase
DU202_RS05525	COG0306	phosphate transporter
DU202_RS05545	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DU202_RS05595	COG4181	ATPase activity
DU202_RS05600	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DU202_RS05625	COG0583	DNA-binding transcription factor activity
DU202_RS05635	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DU202_RS05640	COG1773	rubredoxin
DU202_RS05685	COG2851	Citrate transporter
DU202_RS05695	COG1253	flavin adenine dinucleotide binding
DU202_RS05745	COG0830	nickel cation binding
DU202_RS05760	COG0742	ribosomal rna small subunit methyltransferase
DU202_RS05765	COG0768	penicillin binding
DU202_RS05785	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DU202_RS05790	COG2878	Part of a membrane complex involved in electron transport
DU202_RS05795	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DU202_RS05805	COG3384	dioxygenase
DU202_RS05830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DU202_RS06155	COG0739	heme binding
DU202_RS06245	COG0006	proline dipeptidase activity
DU202_RS06250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DU202_RS06255	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DU202_RS06275	COG1279	arginine transmembrane transporter activity
DU202_RS06280	COG0583	DNA-binding transcription factor activity
DU202_RS06320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DU202_RS06325	COG0741	lytic transglycosylase activity
DU202_RS06325	COG1388	LysM domain
DU202_RS06325	COG1388	LysM domain
DU202_RS06325	COG0741	lytic transglycosylase activity
DU202_RS06335	COG4174	ABC transporter (Permease)
DU202_RS06340	COG4239	(ABC) transporter, permease
DU202_RS06345	COG4172	Belongs to the ABC transporter superfamily
DU202_RS06365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DU202_RS06375	COG2203	Gaf domain
DU202_RS06375	COG3706	GGDEF domain
DU202_RS06375	COG4251	negative regulation of phosphorylation
DU202_RS06375	COG5001	Diguanylate cyclase
DU202_RS06385	COG0446	pyridine nucleotide-disulphide oxidoreductase
DU202_RS06385	COG1902	pentaerythritol trinitrate reductase activity
DU202_RS06395	COG0582	viral genome integration into host DNA
DU202_RS06515	COG3152	Membrane
DU202_RS06535	COG2184	nucleotidyltransferase activity
DU202_RS06545	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DU202_RS06625	COG0789	Transcriptional regulator
DU202_RS06715	COG3038	cytochrome b561
DU202_RS06725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DU202_RS06735	COG0527	aspartate kinase activity
DU202_RS06745	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DU202_RS06755	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DU202_RS06770	COG0667	Aldo Keto reductase
DU202_RS06780	COG1765	OsmC-like protein
DU202_RS06795	COG0542	response to heat
DU202_RS06830	COG2885	chlorophyll binding
DU202_RS06840	COG0625	glutathione transferase activity
DU202_RS06845	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DU202_RS06865	COG3634	alkyl hydroperoxide reductase activity
DU202_RS06875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DU202_RS06885	COG0450	alkyl hydroperoxide reductase
DU202_RS06890	COG1643	Atp-dependent helicase
DU202_RS06905	COG2814	Major facilitator Superfamily
DU202_RS06910	COG3135	benzoate transporter
DU202_RS06915	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS06920	COG0543	2 iron, 2 sulfur cluster binding
DU202_RS06920	COG0633	Ferredoxin
DU202_RS06925	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DU202_RS06930	COG4638	Rieske (2fe-2S)
DU202_RS06935	COG0583	DNA-binding transcription factor activity
DU202_RS06995	COG1570	exodeoxyribonuclease VII activity
DU202_RS07030	COG1280	lysine exporter protein (LysE YggA)
DU202_RS07035	COG1278	Cold shock
DU202_RS07085	COG2814	Major facilitator Superfamily
DU202_RS07125	COG0517	IMP dehydrogenase activity
DU202_RS07125	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DU202_RS07130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DU202_RS07140	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DU202_RS07145	COG1137	ATPase activity
DU202_RS07150	COG1538	Outer membrane efflux protein
DU202_RS07180	COG4122	O-methyltransferase activity
DU202_RS07190	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DU202_RS07205	COG1522	sequence-specific DNA binding
DU202_RS07210	COG5006	permease, DMT superfamily
DU202_RS07220	COG1560	Kdo2-lipid A biosynthetic process
DU202_RS07230	COG2814	Major facilitator Superfamily
DU202_RS07250	COG1250	3-hydroxyacyl-CoA dehydrogenase
DU202_RS07305	COG0583	DNA-binding transcription factor activity
DU202_RS07310	COG1914	H( )-stimulated, divalent metal cation uptake system
DU202_RS07330	COG4770	biotin carboxylase activity
DU202_RS07335	COG0038	chloride channel
DU202_RS07360	COG1309	transcriptional regulator
DU202_RS07370	COG1063	alcohol dehydrogenase
DU202_RS07385	COG0439	Biotin carboxylase
DU202_RS07390	COG2249	NAD(P)H dehydrogenase (quinone) activity
DU202_RS07395	COG1733	regulation of RNA biosynthetic process
DU202_RS07415	COG0864	Transcriptional regulator
DU202_RS07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DU202_RS07430	COG1116	anion transmembrane transporter activity
DU202_RS07450	COG2433	Pfam Transposase IS66
DU202_RS07575	COG0590	tRNA wobble adenosine to inosine editing
DU202_RS07580	COG2807	transmembrane transport
DU202_RS07595	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DU202_RS07605	COG0789	Transcriptional regulator
DU202_RS07615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DU202_RS07635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DU202_RS07645	COG0446	pyridine nucleotide-disulphide oxidoreductase
DU202_RS07660	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS07665	COG0531	amino acid
DU202_RS07670	COG1760	l-serine dehydratase
DU202_RS07675	COG2030	dehydratase
DU202_RS07675	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS07680	COG3396	Phenylacetate-CoA oxygenase
DU202_RS07685	COG3460	Phenylacetate-CoA oxygenase
DU202_RS07690	COG3396	Phenylacetate-CoA oxygenase
DU202_RS07695	COG2151	metal-sulfur cluster biosynthetic enzyme
DU202_RS07700	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DU202_RS07705	COG1024	Enoyl-CoA hydratase
DU202_RS07710	COG1024	Enoyl-CoA hydratase
DU202_RS07715	COG1250	3-hydroxyacyl-CoA dehydrogenase
DU202_RS07720	COG0183	Belongs to the thiolase family
DU202_RS07725	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DU202_RS07730	COG3327	negative regulation of DNA-templated transcription, initiation
DU202_RS07740	COG2050	protein possibly involved in aromatic compounds catabolism
DU202_RS07775	COG0753	catalase activity
DU202_RS07780	COG3038	cytochrome b561
DU202_RS07800	COG2267	carboxylic ester hydrolase activity
DU202_RS07805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DU202_RS07810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DU202_RS07815	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS07820	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DU202_RS07830	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS07835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DU202_RS07840	COG0583	DNA-binding transcription factor activity
DU202_RS07850	COG1414	Transcriptional regulator
DU202_RS07855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DU202_RS07865	COG1840	ABC-type Fe3 transport system, periplasmic component
DU202_RS07870	COG3842	ATPase activity
DU202_RS07885	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DU202_RS07890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DU202_RS07905	COG2814	Major facilitator Superfamily
DU202_RS07910	COG1960	acyl-CoA dehydrogenase activity
DU202_RS07925	COG1024	Enoyl-CoA hydratase
DU202_RS07935	COG2814	Major facilitator Superfamily
DU202_RS07945	COG0183	Belongs to the thiolase family
DU202_RS07950	COG1250	3-hydroxyacyl-CoA dehydrogenase
DU202_RS07955	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS07960	COG1024	Enoyl-CoA hydratase
DU202_RS07965	COG1960	acyl-CoA dehydrogenase activity
DU202_RS07970	COG2814	Major facilitator Superfamily
DU202_RS07975	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DU202_RS07980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DU202_RS07990	COG2814	Major facilitator Superfamily
DU202_RS08000	COG1960	acyl-CoA dehydrogenase activity
DU202_RS08015	COG0583	DNA-binding transcription factor activity
DU202_RS08025	COG4770	biotin carboxylase activity
DU202_RS08030	COG1024	Enoyl-CoA hydratase
DU202_RS08035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DU202_RS08040	COG1960	acyl-CoA dehydrogenase activity
DU202_RS08045	COG1309	transcriptional regulator
DU202_RS08050	COG0318	PFAM AMP-dependent synthetase and ligase
DU202_RS08070	COG0583	DNA-binding transcription factor activity
DU202_RS08130	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS08160	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DU202_RS08190	COG0784	Response regulator, receiver
DU202_RS08190	COG2205	protein histidine kinase activity
DU202_RS08205	COG0765	amino acid transport
DU202_RS08210	COG0765	amino acid transport
DU202_RS08215	COG1126	abc transporter atp-binding protein
DU202_RS08220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DU202_RS08225	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DU202_RS08235	COG1280	lysine exporter protein (LysE YggA)
DU202_RS08240	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DU202_RS08245	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DU202_RS08250	COG1045	serine acetyltransferase
DU202_RS08265	COG0583	DNA-binding transcription factor activity
DU202_RS08270	COG0625	glutathione transferase activity
DU202_RS08275	COG0625	glutathione transferase activity
DU202_RS08280	COG0583	DNA-binding transcription factor activity
DU202_RS08290	COG1346	cytolysis
DU202_RS08310	COG2814	Major facilitator Superfamily
DU202_RS08320	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DU202_RS08325	COG3052	prosthetic group binding
DU202_RS08345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DU202_RS08365	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DU202_RS08375	COG1294	oxidase, subunit
DU202_RS08380	COG1271	oxidase subunit
DU202_RS08405	COG0477	Major facilitator Superfamily
DU202_RS08425	COG4521	taurine ABC transporter
DU202_RS08440	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DU202_RS08445	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DU202_RS08450	COG2175	clavaminate synthase activity
DU202_RS08460	COG1953	Uracil, thiamine, allantoin
DU202_RS08470	COG0583	DNA-binding transcription factor activity
DU202_RS08480	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DU202_RS08505	COG0640	Transcriptional regulator
DU202_RS08510	COG0798	PFAM Bile acid sodium symporter
DU202_RS08515	COG0583	DNA-binding transcription factor activity
DU202_RS08530	COG3634	alkyl hydroperoxide reductase activity
DU202_RS08570	COG0436	Aminotransferase
DU202_RS08580	COG0386	Belongs to the glutathione peroxidase family
DU202_RS08625	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DU202_RS08650	COG0012	GTP binding
DU202_RS08655	COG2011	ABC-type metal ion transport system permease component
DU202_RS08660	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DU202_RS08670	COG1464	Belongs to the NlpA lipoprotein family
DU202_RS08705	COG0765	amino acid transport
DU202_RS08715	COG1126	abc transporter atp-binding protein
DU202_RS08725	COG1522	sequence-specific DNA binding
DU202_RS08740	COG1309	transcriptional regulator
DU202_RS08790	COG0583	DNA-binding transcription factor activity
DU202_RS08800	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DU202_RS08810	COG0697	spore germination
DU202_RS08840	COG3121	Chaperone
DU202_RS08845	COG3539	Fimbrial protein
DU202_RS08875	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DU202_RS08875	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DU202_RS08920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DU202_RS08930	COG2353	YceI-like domain
DU202_RS08940	COG3698	Phosphodiester glycosidase
DU202_RS08955	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DU202_RS08960	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DU202_RS08960	COG0506	proline dehydrogenase activity
DU202_RS08960	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DU202_RS08970	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DU202_RS08975	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DU202_RS09000	COG1132	(ABC) transporter
DU202_RS09005	COG3122	Protein conserved in bacteria
DU202_RS09010	COG3619	membrane
DU202_RS09020	COG0640	Transcriptional regulator
DU202_RS09030	COG2850	peptidyl-arginine hydroxylation
DU202_RS09035	COG0424	maF-like protein
DU202_RS09055	COG0191	fructose-bisphosphate aldolase activity
DU202_RS09060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DU202_RS09075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DU202_RS09085	COG1192	Involved in chromosome partitioning
DU202_RS09090	COG1475	DNA binding
DU202_RS09095	COG0811	peptide transport
DU202_RS09105	COG1132	(ABC) transporter
DU202_RS09110	COG1663	tetraacyldisaccharide 4'-kinase activity
DU202_RS09130	COG0084	hydrolase, TatD family'
DU202_RS09195	COG0776	regulation of translation
DU202_RS09225	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DU202_RS09295	COG0305	Participates in initiation and elongation during chromosome replication
DU202_RS09375	COG4695	Portal protein
DU202_RS09430	COG0741	lytic transglycosylase activity
DU202_RS09430	COG1196	nuclear chromosome segregation
DU202_RS09430	COG0739	heme binding
DU202_RS09495	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DU202_RS09540	COG0339	signal peptide processing
DU202_RS09550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DU202_RS09585	COG0702	epimerase
DU202_RS09590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DU202_RS09610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DU202_RS09640	COG0316	Belongs to the HesB IscA family
DU202_RS09645	COG0822	iron-sulfur transferase activity
DU202_RS09670	COG0776	regulation of translation
DU202_RS09675	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DU202_RS09680	COG2207	Transcriptional regulator
DU202_RS09690	COG1960	acyl-CoA dehydrogenase activity
DU202_RS09695	COG1960	acyl-CoA dehydrogenase activity
DU202_RS09710	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DU202_RS09730	COG4264	IucA IucC family
DU202_RS09735	COG4264	IucA IucC family
DU202_RS09775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DU202_RS09790	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DU202_RS09820	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DU202_RS09825	COG0730	response to heat
DU202_RS09845	COG4773	Receptor
DU202_RS09850	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DU202_RS09865	COG1131	(ABC) transporter
DU202_RS09870	COG0842	Transport permease protein
DU202_RS09875	COG0842	Transport permease protein
DU202_RS09930	COG2226	methyltransferase
DU202_RS09955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DU202_RS09990	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DU202_RS10000	COG0133	tryptophan synthase activity
DU202_RS10015	COG3706	GGDEF domain
DU202_RS10030	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DU202_RS10035	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DU202_RS10040	COG0022	dehydrogenase e1 component
DU202_RS10045	COG0508	dehydrogenase complex catalyzes the overall conversion of
DU202_RS10050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DU202_RS10060	COG1063	alcohol dehydrogenase
DU202_RS10065	COG3781	membrane
DU202_RS10075	COG3453	Protein conserved in bacteria
DU202_RS10075	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DU202_RS10085	COG0730	response to heat
DU202_RS10100	COG3708	Transcriptional regulator
DU202_RS10100	COG2207	Transcriptional regulator
DU202_RS10105	COG1733	regulation of RNA biosynthetic process
DU202_RS10110	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DU202_RS10120	COG2188	Transcriptional regulator
DU202_RS10135	COG4521	taurine ABC transporter
DU202_RS10140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DU202_RS10160	COG0477	Major facilitator Superfamily
DU202_RS10175	COG1027	Aspartate ammonia-lyase
DU202_RS10190	COG0583	DNA-binding transcription factor activity
DU202_RS10200	COG0583	DNA-binding transcription factor activity
DU202_RS10205	COG0583	DNA-binding transcription factor activity
DU202_RS10210	COG0183	Belongs to the thiolase family
DU202_RS10215	COG2031	fatty acid transporter
DU202_RS10220	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DU202_RS10230	COG0583	DNA-binding transcription factor activity
DU202_RS10240	COG2610	gluconate transmembrane transporter activity
DU202_RS10245	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS10250	COG2207	Transcriptional regulator
DU202_RS10265	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS10290	COG0543	2 iron, 2 sulfur cluster binding
DU202_RS10290	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DU202_RS10295	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DU202_RS10300	COG4638	Rieske (2fe-2S)
DU202_RS10310	COG0725	ABC transporter, periplasmic molybdate-binding protein
DU202_RS10315	COG4149	molybdate abc transporter
DU202_RS10320	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DU202_RS10325	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS10330	COG3433	isochorismatase activity
DU202_RS10330	COG1535	isochorismatase
DU202_RS10390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DU202_RS10405	COG0753	catalase activity
DU202_RS10415	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DU202_RS10465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DU202_RS10485	COG2072	flavoprotein involved in K transport
DU202_RS10500	COG1538	Outer membrane efflux protein
DU202_RS10505	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DU202_RS10510	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DU202_RS10515	COG0745	RESPONSE REGULATOR receiver
DU202_RS10520	COG2205	protein histidine kinase activity
DU202_RS10530	COG2207	Transcriptional regulator
DU202_RS10545	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS10580	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DU202_RS10735	COG4397	Mu-like prophage major head subunit gpT
DU202_RS10750	COG5005	Phage virion morphogenesis
DU202_RS10755	COG2369	cell adhesion
DU202_RS10760	COG4383	Mu-like prophage protein gp29
DU202_RS10775	COG4373	Mu-like prophage FluMu protein gp28
DU202_RS10860	COG0776	regulation of translation
DU202_RS10985	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DU202_RS11005	COG1120	ATPase activity
DU202_RS11010	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DU202_RS11025	COG1064	alcohol dehydrogenase
DU202_RS11040	COG2207	Transcriptional regulator
DU202_RS11045	COG2084	Dehydrogenase
DU202_RS11055	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DU202_RS11060	COG0583	DNA-binding transcription factor activity
DU202_RS11070	COG0129	dihydroxy-acid dehydratase activity
DU202_RS11075	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS11090	COG1566	PFAM secretion protein HlyD family protein
DU202_RS11130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DU202_RS11160	COG0583	DNA-binding transcription factor activity
DU202_RS11175	COG2188	Transcriptional regulator
DU202_RS11230	COG3210	domain, Protein
DU202_RS11235	COG2831	hemolysin activation secretion protein
DU202_RS11245	COG1473	amidohydrolase
DU202_RS11255	COG0475	glutathione-regulated potassium exporter activity
DU202_RS11255	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DU202_RS11265	COG0583	DNA-binding transcription factor activity
DU202_RS11270	COG1335	isochorismatase
DU202_RS11280	COG1309	transcriptional regulator
DU202_RS11310	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
DU202_RS11320	COG1902	pentaerythritol trinitrate reductase activity
DU202_RS11320	COG0446	pyridine nucleotide-disulphide oxidoreductase
DU202_RS11335	COG1846	Transcriptional regulator
DU202_RS11360	COG0753	catalase activity
DU202_RS11375	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS11390	COG3162	membrane
DU202_RS11400	COG3829	transcription factor binding
DU202_RS11405	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS11410	COG1960	acyl-CoA dehydrogenase activity
DU202_RS11430	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS11450	COG2186	Transcriptional regulator
DU202_RS11460	COG0583	DNA-binding transcription factor activity
DU202_RS11465	COG4948	Mandelate Racemase Muconate Lactonizing
DU202_RS11470	COG4829	muconolactone delta-isomerase
DU202_RS11480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DU202_RS11485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DU202_RS11490	COG0183	Belongs to the thiolase family
DU202_RS11495	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DU202_RS11505	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS11515	COG3733	amine oxidase
DU202_RS11525	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DU202_RS11535	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS11545	COG4638	Rieske (2fe-2S)
DU202_RS11565	COG0154	amidase activity
DU202_RS11575	COG2814	Major facilitator Superfamily
DU202_RS11600	COG1960	acyl-CoA dehydrogenase activity
DU202_RS11605	COG0583	DNA-binding transcription factor activity
DU202_RS11610	COG1414	Transcriptional regulator
DU202_RS11625	COG2391	methyltransferase activity
DU202_RS11635	COG4993	Dehydrogenase
DU202_RS11640	COG3659	wide pore channel activity
DU202_RS11645	COG3420	alginic acid biosynthetic process
DU202_RS11650	COG0710	3-dehydroquinate dehydratase activity
DU202_RS11655	COG3485	protocatechuate 3,4-dioxygenase
DU202_RS11660	COG3485	protocatechuate 3,4-dioxygenase
DU202_RS11665	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DU202_RS11670	COG2271	Major facilitator Superfamily
DU202_RS11675	COG0596	Alpha beta hydrolase
DU202_RS11680	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DU202_RS11685	COG0183	Belongs to the thiolase family
DU202_RS11690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DU202_RS11695	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DU202_RS11705	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DU202_RS11710	COG2323	membrane
DU202_RS11755	COG0446	pyridine nucleotide-disulphide oxidoreductase
DU202_RS11755	COG1902	pentaerythritol trinitrate reductase activity
DU202_RS11780	COG0542	response to heat
DU202_RS11785	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DU202_RS11815	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DU202_RS11820	COG0569	domain protein
DU202_RS11825	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DU202_RS11840	COG4774	siderophore transport
DU202_RS11845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DU202_RS11855	COG1585	Membrane protein implicated in regulation of membrane protease activity
DU202_RS11880	COG1294	oxidase, subunit
DU202_RS11885	COG4890	Cyd operon protein YbgT
DU202_RS11900	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DU202_RS11910	COG0552	protein localization to endoplasmic reticulum
DU202_RS11935	COG0516	GMP reductase activity
DU202_RS11935	COG0517	IMP dehydrogenase activity
DU202_RS11940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DU202_RS11945	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DU202_RS11955	COG0583	DNA-binding transcription factor activity
DU202_RS11960	COG0024	Methionine aminopeptidase
DU202_RS11990	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DU202_RS11990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DU202_RS11995	COG1105	Belongs to the carbohydrate kinase PfkB family
DU202_RS12000	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DU202_RS12000	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DU202_RS12000	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DU202_RS12020	COG3300	MHYT domain
DU202_RS12020	COG5001	Diguanylate cyclase
DU202_RS12035	COG2135	peptidase activity
DU202_RS12040	COG0659	secondary active sulfate transmembrane transporter activity
DU202_RS12060	COG1113	amino acid transport
DU202_RS12070	COG1522	sequence-specific DNA binding
DU202_RS12095	COG1011	Hydrolase
DU202_RS12100	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DU202_RS12110	COG2137	regulation of response to DNA damage stimulus
DU202_RS12125	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DU202_RS12160	COG0575	Belongs to the CDS family
DU202_RS12165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DU202_RS12185	COG3852	Histidine kinase
DU202_RS12190	COG2204	response regulator
DU202_RS12255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DU202_RS12260	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DU202_RS12280	COG0697	spore germination
DU202_RS12285	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DU202_RS12295	COG0303	'Molybdopterin
DU202_RS12300	COG0315	cyclic pyranopterin monophosphate synthase activity
DU202_RS12300	COG0521	Mo-molybdopterin cofactor biosynthetic process
DU202_RS12315	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DU202_RS12320	COG0243	molybdopterin cofactor binding
DU202_RS12330	COG0243	molybdopterin cofactor binding
DU202_RS12335	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DU202_RS12340	COG2146	nitrite reductase [NAD(P)H] activity
DU202_RS12340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DU202_RS12350	COG0745	RESPONSE REGULATOR receiver
DU202_RS12355	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DU202_RS12355	COG1116	anion transmembrane transporter activity
DU202_RS12370	COG0511	ligase activity, forming carbon-carbon bonds
DU202_RS12385	COG2814	Major facilitator Superfamily
DU202_RS12390	COG2194	sulfuric ester hydrolase activity
DU202_RS12490	COG0741	lytic transglycosylase activity
DU202_RS12490	COG1196	nuclear chromosome segregation
DU202_RS12490	COG0739	heme binding
DU202_RS12505	COG1598	PFAM Uncharacterised protein family UPF0150
DU202_RS12625	COG5410	chromosome segregation
DU202_RS12790	COG0069	glutamate synthase activity
DU202_RS12810	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DU202_RS12820	COG1454	alcohol dehydrogenase
DU202_RS12825	COG0824	Thioesterase
DU202_RS12835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DU202_RS12850	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DU202_RS12855	COG2030	dehydratase
DU202_RS12865	COG0183	Belongs to the thiolase family
DU202_RS12875	COG0583	DNA-binding transcription factor activity
DU202_RS12880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DU202_RS12890	COG1522	sequence-specific DNA binding
DU202_RS12895	COG3135	benzoate transporter
DU202_RS12905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DU202_RS12925	COG0589	response to stress
DU202_RS12930	COG0488	(ABC) transporter
DU202_RS12950	COG4773	Receptor
DU202_RS12985	COG0668	transmembrane transport
DU202_RS12995	COG1309	transcriptional regulator
DU202_RS13015	COG1605	Chorismate mutase
DU202_RS13025	COG4221	oxidoreductase activity
DU202_RS13035	COG0308	aminopeptidase N
DU202_RS13055	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DU202_RS13065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DU202_RS13070	COG1454	alcohol dehydrogenase
DU202_RS13090	COG0531	amino acid
DU202_RS13095	COG4303	Ethanolamine ammonia lyase large subunit
DU202_RS13100	COG4302	ethanolamine ammonia-lyase activity
DU202_RS13105	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DU202_RS13105	COG0519	Catalyzes the synthesis of GMP from XMP
DU202_RS13110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DU202_RS13120	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DU202_RS13135	COG0697	spore germination
DU202_RS13140	COG1923	regulation of RNA biosynthetic process
DU202_RS13150	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DU202_RS13155	COG0802	atpase or kinase
DU202_RS13175	COG1187	pseudouridine synthase activity
DU202_RS13190	COG0583	DNA-binding transcription factor activity
DU202_RS13205	COG2814	Major facilitator Superfamily
DU202_RS13210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DU202_RS13235	COG0729	surface antigen
DU202_RS13255	COG0174	glutamine synthetase
DU202_RS13260	COG0745	RESPONSE REGULATOR receiver
DU202_RS13265	COG2205	protein histidine kinase activity
DU202_RS13275	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DU202_RS13280	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DU202_RS13305	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DU202_RS13310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DU202_RS13315	COG1960	acyl-CoA dehydrogenase activity
DU202_RS13330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DU202_RS13335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DU202_RS13355	COG0583	DNA-binding transcription factor activity
DU202_RS13370	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DU202_RS13380	COG3658	cytochrome
DU202_RS13385	COG1215	transferase activity, transferring glycosyl groups
DU202_RS13390	COG1649	PFAM Uncharacterised BCR, COG1649
DU202_RS13390	COG0726	polysaccharide deacetylase
DU202_RS13425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DU202_RS13430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DU202_RS13440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DU202_RS13465	COG0305	Participates in initiation and elongation during chromosome replication
DU202_RS13470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DU202_RS13480	COG1305	Transglutaminase-like
DU202_RS13490	COG2308	Evidence 4 Homologs of previously reported genes of
DU202_RS13520	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DU202_RS13525	COG0138	bifunctional purine biosynthesis protein purh
DU202_RS13530	COG0151	Belongs to the GarS family
DU202_RS13535	COG1464	Belongs to the NlpA lipoprotein family
DU202_RS13540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DU202_RS13545	COG2011	ABC-type metal ion transport system permease component
DU202_RS13550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DU202_RS13560	COG1301	dicarboxylic acid transport
DU202_RS13600	COG2433	Pfam Transposase IS66
DU202_RS13610	COG3173	Aminoglycoside phosphotransferase
DU202_RS13615	COG0488	(ABC) transporter
DU202_RS13710	COG1794	racemase activity, acting on amino acids and derivatives
DU202_RS13720	COG3008	intermembrane lipid transfer
DU202_RS13720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DU202_RS13725	COG2995	paraquat-inducible protein a
DU202_RS13735	COG2985	domain, Protein
DU202_RS13760	COG0477	Major facilitator Superfamily
DU202_RS13890	COG1610	YqeY-like protein
DU202_RS13895	COG4783	chaperone-mediated protein folding
DU202_RS13920	COG1286	toxin biosynthetic process
DU202_RS14125	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DU202_RS14200	COG0778	Nitroreductase
DU202_RS14210	COG0513	Belongs to the DEAD box helicase family
DU202_RS14230	COG2363	Small membrane protein
DU202_RS14260	COG1234	tRNA 3'-trailer cleavage
DU202_RS14265	COG2195	Cleaves the N-terminal amino acid of tripeptides
DU202_RS14275	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DU202_RS14285	COG2819	hydrolase of the alpha beta superfamily
DU202_RS14290	COG1960	acyl-CoA dehydrogenase activity
DU202_RS14295	COG1301	dicarboxylic acid transport
DU202_RS14300	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DU202_RS14305	COG3139	Protein of unknown function (DUF1315)
DU202_RS14310	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DU202_RS14315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DU202_RS14325	COG0494	nUDIX hydrolase
DU202_RS14335	COG0642	Histidine kinase
DU202_RS14350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DU202_RS14360	COG1720	tRNA m6t6A37 methyltransferase activity
DU202_RS14375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DU202_RS14380	COG0826	peptidase U32
DU202_RS14385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DU202_RS14395	COG4598	ABC transporter
DU202_RS14400	COG4160	amino acid transport
DU202_RS14405	COG4215	(ABC) transporter
DU202_RS14420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DU202_RS14465	COG1131	(ABC) transporter
DU202_RS14470	COG0842	Transport permease protein
DU202_RS14485	COG0772	Belongs to the SEDS family
DU202_RS14490	COG2951	lytic endotransglycosylase activity
DU202_RS14515	COG2207	Transcriptional regulator
DU202_RS14530	COG0052	Belongs to the universal ribosomal protein uS2 family
DU202_RS14535	COG0024	Methionine aminopeptidase
DU202_RS14545	COG2223	nitrite transmembrane transporter activity
DU202_RS14560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DU202_RS14565	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DU202_RS14570	COG1960	acyl-CoA dehydrogenase activity
DU202_RS14585	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DU202_RS14590	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DU202_RS14595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DU202_RS14625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DU202_RS14630	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DU202_RS14635	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DU202_RS14670	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DU202_RS14680	COG0174	glutamine synthetase
DU202_RS14695	COG0582	viral genome integration into host DNA
DU202_RS14755	COG0739	heme binding
DU202_RS14870	COG5410	chromosome segregation
DU202_RS15045	COG0512	Glutamine amidotransferase of anthranilate synthase
DU202_RS15050	COG0308	aminopeptidase N
DU202_RS15090	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DU202_RS15100	COG0302	gtp cyclohydrolase
DU202_RS15130	COG3739	integral membrane protein
DU202_RS15145	COG1169	isochorismate synthase
DU202_RS15155	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DU202_RS15160	COG1132	(ABC) transporter
DU202_RS15165	COG1132	(ABC) transporter
DU202_RS15180	COG1535	isochorismatase
DU202_RS15180	COG3433	isochorismatase activity
DU202_RS15185	COG1021	2,3-dihydroxybenzoate-AMP ligase
DU202_RS15190	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DU202_RS15200	COG4774	siderophore transport
DU202_RS15205	COG4607	ABC-type enterochelin transport system periplasmic component
DU202_RS15210	COG4604	ABC transporter, ATP-binding protein
DU202_RS15215	COG4605	iron ion homeostasis
DU202_RS15220	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DU202_RS15225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DU202_RS15240	COG2964	Protein conserved in bacteria
DU202_RS15250	COG1741	Belongs to the pirin family
DU202_RS15265	COG1309	transcriptional regulator
DU202_RS15275	COG4948	Mandelate Racemase Muconate Lactonizing
DU202_RS15280	COG2814	Major facilitator Superfamily
DU202_RS15315	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DU202_RS15315	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DU202_RS15320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DU202_RS15325	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS15335	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DU202_RS15345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DU202_RS15350	COG0583	DNA-binding transcription factor activity
DU202_RS15355	COG1113	amino acid transport
DU202_RS15375	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DU202_RS15375	COG2508	Transcriptional regulator
DU202_RS15405	COG2879	small protein
DU202_RS15410	COG1966	Carbon starvation protein
DU202_RS15455	COG1067	ATP-dependent peptidase activity
DU202_RS15460	COG0583	DNA-binding transcription factor activity
DU202_RS15485	COG1686	Belongs to the peptidase S11 family
DU202_RS15490	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DU202_RS15525	COG0616	signal peptide processing
DU202_RS15530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DU202_RS15540	COG0573	inorganic phosphate transmembrane transporter activity
DU202_RS15545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DU202_RS15550	COG1113	amino acid transport
DU202_RS15555	COG3961	Belongs to the TPP enzyme family
DU202_RS15560	COG1522	sequence-specific DNA binding
DU202_RS15570	COG0076	glutamate decarboxylase activity
DU202_RS15575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DU202_RS15585	COG1309	transcriptional regulator
DU202_RS15600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DU202_RS15635	COG0352	thiamine-phosphate diphosphorylase activity
DU202_RS15660	COG0612	Peptidase, M16
DU202_RS15670	COG1823	symporter activity
DU202_RS15675	COG0583	DNA-binding transcription factor activity
DU202_RS15680	COG0477	Major facilitator Superfamily
DU202_RS15700	COG1187	pseudouridine synthase activity
DU202_RS15715	COG1686	Belongs to the peptidase S11 family
DU202_RS15720	COG1252	NADH dehydrogenase
DU202_RS15730	COG0415	Belongs to the DNA photolyase family
DU202_RS15745	COG1215	transferase activity, transferring glycosyl groups
DU202_RS15775	COG2070	2-Nitropropane dioxygenase
DU202_RS15830	COG0556	nucleotide-excision repair
DU202_RS15850	COG0436	Aminotransferase
DU202_RS15875	COG4221	oxidoreductase activity
DU202_RS15885	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DU202_RS15890	COG1381	Involved in DNA repair and RecF pathway recombination
DU202_RS15900	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DU202_RS15915	COG0681	Belongs to the peptidase S26 family
DU202_RS15930	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DU202_RS15950	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DU202_RS15955	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DU202_RS15960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DU202_RS15970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DU202_RS15975	COG4208	sulfate ABC transporter
DU202_RS15980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DU202_RS15985	COG0583	DNA-binding transcription factor activity
DU202_RS15990	COG4625	pathogenesis
DU202_RS16005	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DU202_RS16020	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DU202_RS16030	COG1051	belongs to the nudix hydrolase family
DU202_RS16030	COG1056	cytidyltransferase-related domain
DU202_RS16035	COG1024	Enoyl-CoA hydratase
DU202_RS16050	COG2814	Major facilitator Superfamily
DU202_RS16055	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DU202_RS16055	COG0047	phosphoribosylformylglycinamidine synthase activity
DU202_RS16075	COG1473	amidohydrolase
DU202_RS16080	COG0824	Thioesterase
DU202_RS16100	COG0823	Involved in the tonB-independent uptake of proteins
DU202_RS16120	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DU202_RS16155	COG0628	permease
DU202_RS16165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DU202_RS16170	COG0596	Alpha beta hydrolase
DU202_RS16175	COG0616	signal peptide processing
DU202_RS16175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DU202_RS16185	COG0658	competence protein
DU202_RS16185	COG2333	competence protein COMEC
DU202_RS16190	COG1136	(ABC) transporter
DU202_RS16195	COG4591	ABC-type transport system involved in lipoprotein release permease component
DU202_RS16225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DU202_RS16245	COG0463	Glycosyl transferase, family 2
DU202_RS16275	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DU202_RS16280	COG1280	lysine exporter protein (LysE YggA)
DU202_RS16290	COG0019	diaminopimelate decarboxylase activity
DU202_RS16300	COG1113	amino acid transport
DU202_RS16315	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DU202_RS16325	COG3339	Conserved Protein
DU202_RS16330	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DU202_RS16335	COG0243	molybdopterin cofactor binding
DU202_RS16340	COG1929	Belongs to the glycerate kinase type-1 family
DU202_RS16355	COG0778	Nitroreductase
DU202_RS16385	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DU202_RS16405	COG0741	lytic transglycosylase activity
DU202_RS16425	COG0584	glycerophosphoryl diester phosphodiesterase
DU202_RS16430	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DU202_RS16470	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DU202_RS16500	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DU202_RS16505	COG0477	Major facilitator Superfamily
DU202_RS16555	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
DU202_RS16560	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DU202_RS16585	COG0505	Belongs to the CarA family
DU202_RS16605	COG0589	response to stress
DU202_RS16650	COG2321	neutral zinc metallopeptidase
DU202_RS16655	COG2354	Protein conserved in bacteria
DU202_RS16675	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DU202_RS16690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DU202_RS16695	COG1053	succinate dehydrogenase
DU202_RS16700	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DU202_RS16705	COG2009	succinate dehydrogenase
DU202_RS16745	COG2921	Belongs to the UPF0250 family
DU202_RS16750	COG0321	lipoyl(octanoyl) transferase activity
DU202_RS16765	COG0531	amino acid
DU202_RS16775	COG1733	regulation of RNA biosynthetic process
DU202_RS16780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DU202_RS16785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DU202_RS16785	COG1648	precorrin-2 dehydrogenase activity
DU202_RS16800	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DU202_RS16855	COG0671	phosphoesterase, PA-phosphatase related
DU202_RS16860	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DU202_RS16870	COG1538	Outer membrane efflux protein
DU202_RS16875	COG0393	Putative heavy-metal-binding
DU202_RS16880	COG0393	Putative heavy-metal-binding
DU202_RS16890	COG1028	Short-chain dehydrogenase reductase Sdr
DU202_RS16900	COG0525	valine-tRNA ligase activity
DU202_RS16920	COG0583	DNA-binding transcription factor activity
DU202_RS16925	COG0004	ammonium transporteR
DU202_RS16935	COG0642	Histidine kinase
DU202_RS16940	COG0745	RESPONSE REGULATOR receiver
DU202_RS16945	COG2194	sulfuric ester hydrolase activity
DU202_RS16965	COG1752	Esterase of the alpha-beta hydrolase superfamily
DU202_RS16980	COG2315	Protein conserved in bacteria
DU202_RS16985	COG0142	geranyltranstransferase activity
DU202_RS16990	COG2828	Protein conserved in bacteria
DU202_RS16995	COG1113	amino acid transport
DU202_RS17015	COG2207	Transcriptional regulator
DU202_RS17060	COG2249	NAD(P)H dehydrogenase (quinone) activity
DU202_RS17070	COG0560	Phosphoserine phosphatase
DU202_RS17080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DU202_RS17090	COG1530	ribonuclease E activity
DU202_RS17095	COG0424	maF-like protein
DU202_RS17100	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DU202_RS17105	COG1792	Involved in formation and maintenance of cell shape
DU202_RS17110	COG1077	Cell shape determining protein MreB Mrl
DU202_RS17115	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DU202_RS17125	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DU202_RS17165	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DU202_RS17170	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DU202_RS17175	COG1752	Esterase of the alpha-beta hydrolase superfamily
DU202_RS17180	COG1115	amino acid carrier protein
DU202_RS17195	COG2814	Major facilitator Superfamily
DU202_RS17200	COG1289	transmembrane transporter activity
DU202_RS17210	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DU202_RS17250	COG1376	ErfK ybiS ycfS ynhG family protein
DU202_RS17255	COG2832	Protein of unknown function (DUF454)
DU202_RS17265	COG5510	response to toxic substance
DU202_RS17285	COG0840	transmembrane signaling receptor activity
DU202_RS17325	COG3422	double-strand break repair
DU202_RS17330	COG2824	Alkylphosphonate utilization operon protein PhnA
DU202_RS17335	COG3189	MarR family transcriptional regulator
DU202_RS17345	COG0354	folic acid binding
DU202_RS17350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DU202_RS17360	COG0679	Auxin Efflux Carrier
DU202_RS17365	COG1902	pentaerythritol trinitrate reductase activity
DU202_RS17370	COG4772	TonB-dependent receptor
DU202_RS17375	COG2094	Belongs to the DNA glycosylase MPG family
DU202_RS17400	COG1217	gtp-binding protein TYPA
DU202_RS17405	COG2233	PERMEase
DU202_RS17415	COG0833	amino acid
DU202_RS17420	COG1690	Belongs to the RtcB family
DU202_RS17430	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DU202_RS17430	COG2885	chlorophyll binding
DU202_RS17440	COG0183	Belongs to the thiolase family
DU202_RS17465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DU202_RS17485	COG2207	Transcriptional regulator
DU202_RS17490	COG0183	Belongs to the thiolase family
DU202_RS17520	COG1272	protein, Hemolysin III
DU202_RS17525	COG0477	Major facilitator Superfamily
DU202_RS17540	COG0450	alkyl hydroperoxide reductase
DU202_RS17560	COG0285	dihydrofolate synthase activity
DU202_RS17610	COG2096	Adenosyltransferase
DU202_RS17630	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DU202_RS17635	COG0745	RESPONSE REGULATOR receiver
DU202_RS17640	COG2205	protein histidine kinase activity
DU202_RS17650	COG1960	acyl-CoA dehydrogenase activity
DU202_RS17655	COG1960	acyl-CoA dehydrogenase activity
DU202_RS17660	COG0583	DNA-binding transcription factor activity
DU202_RS17665	COG0625	glutathione transferase activity
DU202_RS17730	COG0438	transferase activity, transferring glycosyl groups
DU202_RS17735	COG0463	Glycosyl transferase, family 2
DU202_RS17760	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DU202_RS17765	COG2205	protein histidine kinase activity
DU202_RS17820	COG1862	Preprotein translocase
DU202_RS17830	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DU202_RS17835	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DU202_RS17845	COG3781	membrane
DU202_RS17850	COG0613	PHP domain protein
DU202_RS17860	COG2350	Protein conserved in bacteria
DU202_RS17890	COG1607	acyl-coa hydrolase
DU202_RS17950	COG2199	diguanylate cyclase activity
DU202_RS17960	COG1408	metallophosphoesterase
DU202_RS17965	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DU202_RS17975	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DU202_RS17995	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DU202_RS18000	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DU202_RS18015	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DU202_RS18025	COG2969	positive regulation of protein catabolic process
DU202_RS18045	COG1960	acyl-CoA dehydrogenase activity
DU202_RS18050	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DU202_RS18065	COG1309	transcriptional regulator
DU202_RS18070	COG1960	acyl-CoA dehydrogenase activity
DU202_RS18115	COG1183	phosphatidylcholine synthase activity
DU202_RS18120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DU202_RS18150	COG1196	nuclear chromosome segregation
DU202_RS18150	COG0741	lytic transglycosylase activity
DU202_RS18150	COG0739	heme binding
DU202_RS18160	COG1702	phosphate starvation-inducible protein PhoH
DU202_RS18195	COG1295	ribonuclease BN
DU202_RS18200	COG0697	spore germination
DU202_RS18205	COG2169	Transcriptional regulator
DU202_RS18210	COG0179	Fumarylacetoacetate (FAA) hydrolase
DU202_RS18255	COG0557	exoribonuclease II activity
DU202_RS18260	COG0339	signal peptide processing
DU202_RS18265	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DU202_RS18295	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DU202_RS18300	COG1960	acyl-CoA dehydrogenase activity
DU202_RS18455	COG0626	cystathionine gamma-synthase activity
DU202_RS18460	COG0433	COG0433 Predicted ATPase
DU202_RS18465	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DU202_RS18465	COG1017	nitric oxide dioxygenase activity
DU202_RS18470	COG1959	2 iron, 2 sulfur cluster binding
DU202_RS18485	COG1301	dicarboxylic acid transport
DU202_RS18490	COG1946	Acyl-CoA thioesterase
DU202_RS18510	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DU202_RS18515	COG1040	competence protein
DU202_RS18520	COG0494	nUDIX hydrolase
DU202_RS18530	COG0598	Magnesium transport protein CorA
DU202_RS18540	COG2854	intermembrane phospholipid transfer
DU202_RS18550	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DU202_RS18555	COG1127	ABC transporter
DU202_RS18565	COG0513	Belongs to the DEAD box helicase family
DU202_RS18585	COG0408	coproporphyrinogen oxidase activity
DU202_RS18600	COG1960	acyl-CoA dehydrogenase activity
DU202_RS18610	COG1983	PspC domain protein
DU202_RS18615	COG0517	IMP dehydrogenase activity
DU202_RS18660	COG0583	DNA-binding transcription factor activity
DU202_RS18700	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS18710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DU202_RS18715	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DU202_RS18720	COG0833	amino acid
DU202_RS18750	COG1192	Involved in chromosome partitioning
DU202_RS18755	COG0628	permease
DU202_RS18765	COG1289	transmembrane transporter activity
DU202_RS18780	COG2249	NAD(P)H dehydrogenase (quinone) activity
DU202_RS18785	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DU202_RS18795	COG0277	FAD linked oxidase domain protein
DU202_RS18800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DU202_RS18825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DU202_RS18830	COG5380	lipid catabolic process
DU202_RS18850	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DU202_RS18900	COG0194	GDP metabolic process
DU202_RS18910	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DU202_RS18930	COG3307	-O-antigen
DU202_RS18950	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DU202_RS18955	COG1704	LemA family
DU202_RS18965	COG0493	'glutamate synthase
DU202_RS18970	COG0070	glutamate synthase
DU202_RS18970	COG0069	glutamate synthase activity
DU202_RS18970	COG0067	glutamate synthase
DU202_RS19020	COG2226	methyltransferase
DU202_RS19035	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DU202_RS19040	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DU202_RS19085	COG0833	amino acid
DU202_RS19150	COG0488	(ABC) transporter
DU202_RS19155	COG2873	o-acetylhomoserine
DU202_RS19160	COG4221	oxidoreductase activity
DU202_RS19165	COG0659	secondary active sulfate transmembrane transporter activity
DU202_RS19185	COG0427	acetyl-CoA hydrolase
DU202_RS19215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DU202_RS19255	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DU202_RS19310	COG2207	Transcriptional regulator
DU202_RS19315	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
DU202_RS19330	COG2249	NAD(P)H dehydrogenase (quinone) activity
DU202_RS19335	COG1733	regulation of RNA biosynthetic process
DU202_RS19350	COG1733	regulation of RNA biosynthetic process
DU202_RS19380	COG0667	Aldo Keto reductase
DU202_RS19405	COG0583	DNA-binding transcription factor activity
DU202_RS19410	COG2814	Major facilitator Superfamily
DU202_RS19440	COG1335	isochorismatase
DU202_RS19450	COG1012	belongs to the aldehyde dehydrogenase family
DU202_RS19455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DU202_RS19465	COG1113	amino acid transport
DU202_RS19475	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DU202_RS19490	COG2814	Major facilitator Superfamily
DU202_RS19500	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DU202_RS19500	COG0352	thiamine-phosphate diphosphorylase activity
DU202_RS19500	COG0351	phosphomethylpyrimidine kinase
DU202_RS19520	COG1309	transcriptional regulator
DU202_RS19525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DU202_RS19540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DU202_RS19550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DU202_RS19555	COG3162	membrane
DU202_RS19560	COG2198	Histidine kinase
DU202_RS19560	COG2205	protein histidine kinase activity
DU202_RS19560	COG0784	Response regulator, receiver
DU202_RS19585	COG1522	sequence-specific DNA binding
DU202_RS19590	COG1335	isochorismatase
DU202_RS19595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DU202_RS19605	COG0668	transmembrane transport
DU202_RS19610	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DU202_RS19615	COG1519	Transferase
DU202_RS19620	COG1902	pentaerythritol trinitrate reductase activity
DU202_RS19640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DU202_RS19665	COG0426	domain, Protein
DU202_RS19665	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DU202_RS19670	COG4774	siderophore transport
DU202_RS19685	COG2119	membrane
DU202_RS19695	COG0508	dehydrogenase complex catalyzes the overall conversion of
DU202_RS19705	COG4942	peptidase
DU202_RS19720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DU202_RS19730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DU202_RS19750	COG0189	ligase activity
DU202_RS19775	COG0708	Exodeoxyribonuclease III
DU202_RS19780	COG1393	Belongs to the ArsC family
DU202_RS19835	COG2233	PERMEase
DU202_RS19845	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DU202_RS19855	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DU202_RS19865	COG3150	esterase
DU202_RS19890	COG3179	chitinase
DU202_RS19905	COG2918	glutathione biosynthetic process
DU202_RS19920	COG2733	membrane
DU202_RS19925	COG0436	Aminotransferase
DU202_RS19930	COG0534	Mate efflux family protein
DU202_RS19990	COG0753	catalase activity
DU202_RS20035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DU202_RS20040	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DU202_RS20050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DU202_RS20055	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DU202_RS20060	COG0546	phosphoglycolate phosphatase activity
DU202_RS20070	COG0010	Belongs to the arginase family
DU202_RS20115	COG2188	Transcriptional regulator
DU202_RS20125	COG0523	cobalamin synthesis protein
DU202_RS20135	COG1113	amino acid transport
DU202_RS20145	COG0625	glutathione transferase activity
DU202_RS20165	COG1683	Conserved Protein
DU202_RS20170	COG0534	Mate efflux family protein
DU202_RS20180	COG0385	Bile acid
DU202_RS20185	COG1335	isochorismatase
DU202_RS20190	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DU202_RS20215	COG2116	formate transmembrane transporter activity
DU202_RS20220	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DU202_RS20225	COG2133	pyrroloquinoline quinone binding
DU202_RS20230	COG2983	Belongs to the UPF0260 family
DU202_RS20265	COG2818	Glycosylase
DU202_RS20270	COG1064	alcohol dehydrogenase
DU202_RS20275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DU202_RS20285	COG0583	DNA-binding transcription factor activity
DU202_RS20290	COG0656	L-ascorbic acid biosynthetic process
DU202_RS20295	COG2814	Major facilitator Superfamily
DU202_RS20330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DU202_RS20345	COG2233	PERMEase
DU202_RS20385	COG0733	neurotransmitter:sodium symporter activity
DU202_RS20425	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DU202_RS20430	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DU202_RS20435	COG0596	Alpha beta hydrolase