locus-tag	class	description
H2787_RS00010	COG0592	DNA-directed DNA polymerase activity
H2787_RS00020	COG0187	DNA topoisomerase II activity
H2787_RS00030	COG0586	Pfam SNARE associated Golgi protein
H2787_RS00035	COG0488	(ABC) transporter
H2787_RS00070	COG0596	Alpha beta hydrolase
H2787_RS00075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H2787_RS00080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H2787_RS00125	COG0733	neurotransmitter:sodium symporter activity
H2787_RS00160	COG0583	DNA-binding transcription factor activity
H2787_RS00165	COG2233	PERMEase
H2787_RS00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2787_RS00215	COG2814	Major facilitator Superfamily
H2787_RS00220	COG0656	L-ascorbic acid biosynthetic process
H2787_RS00225	COG0583	DNA-binding transcription factor activity
H2787_RS00245	COG1064	alcohol dehydrogenase
H2787_RS00250	COG2818	Glycosylase
H2787_RS00265	COG1194	a g-specific adenine glycosylase
H2787_RS00275	COG0400	carboxylic ester hydrolase activity
H2787_RS00285	COG2983	Belongs to the UPF0260 family
H2787_RS00290	COG2133	pyrroloquinoline quinone binding
H2787_RS00295	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H2787_RS00300	COG2116	formate transmembrane transporter activity
H2787_RS00320	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2787_RS00325	COG1335	isochorismatase
H2787_RS00330	COG0385	Bile acid
H2787_RS00335	COG0534	Mate efflux family protein
H2787_RS00340	COG1683	Conserved Protein
H2787_RS00370	COG0625	glutathione transferase activity
H2787_RS00380	COG1113	amino acid transport
H2787_RS00390	COG0523	cobalamin synthesis protein
H2787_RS00400	COG2188	Transcriptional regulator
H2787_RS00430	COG0010	Belongs to the arginase family
H2787_RS00465	COG4372	Transposase
H2787_RS00475	COG2963	transposase activity
H2787_RS00480	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H2787_RS00490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H2787_RS00495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H2787_RS00580	COG0534	Mate efflux family protein
H2787_RS00585	COG0436	Aminotransferase
H2787_RS00590	COG2733	membrane
H2787_RS00605	COG2918	glutathione biosynthetic process
H2787_RS00625	COG3150	esterase
H2787_RS00635	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H2787_RS00645	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2787_RS00655	COG2233	PERMEase
H2787_RS00660	COG2351	hydroxyisourate hydrolase activity
H2787_RS00695	COG3706	GGDEF domain
H2787_RS00710	COG1393	Belongs to the ArsC family
H2787_RS00715	COG0708	Exodeoxyribonuclease III
H2787_RS00735	COG0189	ligase activity
H2787_RS00755	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H2787_RS00765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H2787_RS00780	COG4942	peptidase
H2787_RS00790	COG0508	dehydrogenase complex catalyzes the overall conversion of
H2787_RS00800	COG2119	membrane
H2787_RS00840	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H2787_RS00870	COG1902	pentaerythritol trinitrate reductase activity
H2787_RS00875	COG1519	Transferase
H2787_RS00880	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H2787_RS00885	COG0668	transmembrane transport
H2787_RS00895	COG3293	Transposase
H2787_RS00905	COG3293	Transposase
H2787_RS00910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H2787_RS00915	COG1335	isochorismatase
H2787_RS00920	COG1522	sequence-specific DNA binding
H2787_RS00955	COG0784	Response regulator, receiver
H2787_RS00955	COG2198	Histidine kinase
H2787_RS00955	COG2205	protein histidine kinase activity
H2787_RS00965	COG3162	membrane
H2787_RS00970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2787_RS01000	COG3293	Transposase
H2787_RS01010	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H2787_RS01015	COG1309	transcriptional regulator
H2787_RS01035	COG0351	phosphomethylpyrimidine kinase
H2787_RS01035	COG0352	thiamine-phosphate diphosphorylase activity
H2787_RS01035	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H2787_RS01045	COG2814	Major facilitator Superfamily
H2787_RS01060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H2787_RS01070	COG1113	amino acid transport
H2787_RS01080	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2787_RS01085	COG1012	belongs to the aldehyde dehydrogenase family
H2787_RS01095	COG1335	isochorismatase
H2787_RS01125	COG2814	Major facilitator Superfamily
H2787_RS01130	COG0583	DNA-binding transcription factor activity
H2787_RS01150	COG0667	Aldo Keto reductase
H2787_RS01170	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2787_RS01245	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H2787_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H2787_RS01325	COG0427	acetyl-CoA hydrolase
H2787_RS01350	COG0659	secondary active sulfate transmembrane transporter activity
H2787_RS01355	COG4221	oxidoreductase activity
H2787_RS01360	COG2873	o-acetylhomoserine
H2787_RS01365	COG0488	(ABC) transporter
H2787_RS01460	COG0833	amino acid
H2787_RS01490	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS01510	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H2787_RS01515	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H2787_RS01530	COG2226	methyltransferase
H2787_RS01590	COG0070	glutamate synthase
H2787_RS01590	COG0069	glutamate synthase activity
H2787_RS01590	COG0067	glutamate synthase
H2787_RS01595	COG0493	'glutamate synthase
H2787_RS01605	COG1704	LemA family
H2787_RS01610	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H2787_RS01630	COG3307	-O-antigen
H2787_RS01650	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H2787_RS01665	COG0194	GDP metabolic process
H2787_RS01680	COG4969	Belongs to the N-Me-Phe pilin family
H2787_RS01695	COG3293	Transposase
H2787_RS01715	COG3328	transposase activity
H2787_RS01730	COG3293	Transposase
H2787_RS01745	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H2787_RS01765	COG5380	lipid catabolic process
H2787_RS01770	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H2787_RS01795	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H2787_RS01800	COG0277	FAD linked oxidase domain protein
H2787_RS01810	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H2787_RS01815	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2787_RS01830	COG1289	transmembrane transporter activity
H2787_RS01840	COG0628	permease
H2787_RS01845	COG1192	Involved in chromosome partitioning
H2787_RS01875	COG0833	amino acid
H2787_RS01900	COG0471	metal ion transport
H2787_RS01905	COG2194	sulfuric ester hydrolase activity
H2787_RS01910	COG0745	RESPONSE REGULATOR receiver
H2787_RS01915	COG0642	Histidine kinase
H2787_RS01955	COG0789	Transcriptional regulator
H2787_RS01980	COG0789	Transcriptional regulator
H2787_RS02055	COG0517	IMP dehydrogenase activity
H2787_RS02060	COG1983	PspC domain protein
H2787_RS02070	COG1960	acyl-CoA dehydrogenase activity
H2787_RS02085	COG0408	coproporphyrinogen oxidase activity
H2787_RS02105	COG0513	Belongs to the DEAD box helicase family
H2787_RS02115	COG1127	ABC transporter
H2787_RS02120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H2787_RS02130	COG2854	intermembrane phospholipid transfer
H2787_RS02140	COG0598	Magnesium transport protein CorA
H2787_RS02150	COG0494	nUDIX hydrolase
H2787_RS02155	COG1040	competence protein
H2787_RS02160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H2787_RS02180	COG1946	Acyl-CoA thioesterase
H2787_RS02185	COG1301	dicarboxylic acid transport
H2787_RS02200	COG1959	2 iron, 2 sulfur cluster binding
H2787_RS02205	COG1017	nitric oxide dioxygenase activity
H2787_RS02205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2787_RS02215	COG0433	COG0433 Predicted ATPase
H2787_RS02220	COG0626	cystathionine gamma-synthase activity
H2787_RS02380	COG1960	acyl-CoA dehydrogenase activity
H2787_RS02385	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H2787_RS02410	COG3328	transposase activity
H2787_RS02425	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H2787_RS02430	COG0339	signal peptide processing
H2787_RS02435	COG0557	exoribonuclease II activity
H2787_RS02485	COG0179	Fumarylacetoacetate (FAA) hydrolase
H2787_RS02490	COG2169	Transcriptional regulator
H2787_RS02495	COG0697	spore germination
H2787_RS02500	COG1295	ribonuclease BN
H2787_RS02535	COG1702	phosphate starvation-inducible protein PhoH
H2787_RS02545	COG0739	heme binding
H2787_RS02545	COG0741	lytic transglycosylase activity
H2787_RS02545	COG1196	nuclear chromosome segregation
H2787_RS02575	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H2787_RS02580	COG1183	phosphatidylcholine synthase activity
H2787_RS02625	COG1960	acyl-CoA dehydrogenase activity
H2787_RS02630	COG1309	transcriptional regulator
H2787_RS02645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H2787_RS02650	COG1960	acyl-CoA dehydrogenase activity
H2787_RS02670	COG2969	positive regulation of protein catabolic process
H2787_RS02680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H2787_RS02695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H2787_RS02700	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H2787_RS02720	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H2787_RS02730	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2787_RS02735	COG1408	metallophosphoesterase
H2787_RS02820	COG1607	acyl-coa hydrolase
H2787_RS02830	COG3293	Transposase
H2787_RS02860	COG2350	Protein conserved in bacteria
H2787_RS02870	COG0613	PHP domain protein
H2787_RS02875	COG3781	membrane
H2787_RS02885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H2787_RS02890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H2787_RS02900	COG1862	Preprotein translocase
H2787_RS02950	COG0629	single-stranded DNA binding
H2787_RS02995	COG3646	Phage regulatory protein
H2787_RS03005	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
H2787_RS03145	COG4695	Portal protein
H2787_RS03150	COG2205	protein histidine kinase activity
H2787_RS03155	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H2787_RS03170	COG0726	polysaccharide deacetylase
H2787_RS03175	COG0438	transferase activity, transferring glycosyl groups
H2787_RS03185	COG0438	transferase activity, transferring glycosyl groups
H2787_RS03190	COG3293	Transposase
H2787_RS03195	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS03275	COG1960	acyl-CoA dehydrogenase activity
H2787_RS03280	COG1960	acyl-CoA dehydrogenase activity
H2787_RS03290	COG2205	protein histidine kinase activity
H2787_RS03295	COG0745	RESPONSE REGULATOR receiver
H2787_RS03300	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H2787_RS03315	COG0584	glycerophosphoryl diester phosphodiesterase
H2787_RS03320	COG2096	Adenosyltransferase
H2787_RS03325	COG4206	TonB-dependent receptor
H2787_RS03370	COG0285	dihydrofolate synthase activity
H2787_RS03390	COG0450	alkyl hydroperoxide reductase
H2787_RS03405	COG0477	Major facilitator Superfamily
H2787_RS03410	COG1272	protein, Hemolysin III
H2787_RS03440	COG0183	Belongs to the thiolase family
H2787_RS03445	COG2207	Transcriptional regulator
H2787_RS03465	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2787_RS03485	COG0183	Belongs to the thiolase family
H2787_RS03510	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H2787_RS03510	COG2885	chlorophyll binding
H2787_RS03520	COG1690	Belongs to the RtcB family
H2787_RS03525	COG0833	amino acid
H2787_RS03535	COG2233	PERMEase
H2787_RS03540	COG1217	gtp-binding protein TYPA
H2787_RS03565	COG2094	Belongs to the DNA glycosylase MPG family
H2787_RS03570	COG4772	TonB-dependent receptor
H2787_RS03575	COG1902	pentaerythritol trinitrate reductase activity
H2787_RS03585	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS03600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2787_RS03605	COG0354	folic acid binding
H2787_RS03620	COG2233	PERMEase
H2787_RS03625	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2787_RS03630	COG0251	oxidation-reduction process
H2787_RS03635	COG1335	isochorismatase
H2787_RS03640	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2787_RS03650	COG0596	Alpha beta hydrolase
H2787_RS03655	COG3189	MarR family transcriptional regulator
H2787_RS03660	COG2824	Alkylphosphonate utilization operon protein PhnA
H2787_RS03665	COG3422	double-strand break repair
H2787_RS03705	COG0840	transmembrane signaling receptor activity
H2787_RS03725	COG5510	response to toxic substance
H2787_RS03735	COG2832	Protein of unknown function (DUF454)
H2787_RS03740	COG1376	ErfK ybiS ycfS ynhG family protein
H2787_RS03780	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H2787_RS03790	COG1289	transmembrane transporter activity
H2787_RS03805	COG4372	Transposase
H2787_RS03810	COG2814	Major facilitator Superfamily
H2787_RS03830	COG1115	amino acid carrier protein
H2787_RS03835	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2787_RS03840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H2787_RS03845	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H2787_RS03855	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS03875	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H2787_RS03885	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H2787_RS03890	COG1077	Cell shape determining protein MreB Mrl
H2787_RS03895	COG1792	Involved in formation and maintenance of cell shape
H2787_RS03900	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H2787_RS03905	COG0424	maF-like protein
H2787_RS03910	COG1530	ribonuclease E activity
H2787_RS03920	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2787_RS03930	COG0560	Phosphoserine phosphatase
H2787_RS03940	COG2249	NAD(P)H dehydrogenase (quinone) activity
H2787_RS03965	COG2207	Transcriptional regulator
H2787_RS04020	COG0582	viral genome integration into host DNA
H2787_RS04030	COG1113	amino acid transport
H2787_RS04035	COG2828	Protein conserved in bacteria
H2787_RS04040	COG0142	geranyltranstransferase activity
H2787_RS04045	COG2315	Protein conserved in bacteria
H2787_RS04060	COG1752	Esterase of the alpha-beta hydrolase superfamily
H2787_RS04085	COG0745	RESPONSE REGULATOR receiver
H2787_RS04090	COG0642	Histidine kinase
H2787_RS04100	COG0004	ammonium transporteR
H2787_RS04105	COG0583	DNA-binding transcription factor activity
H2787_RS04135	COG0525	valine-tRNA ligase activity
H2787_RS04145	COG1028	Short-chain dehydrogenase reductase Sdr
H2787_RS04155	COG0393	Putative heavy-metal-binding
H2787_RS04160	COG0393	Putative heavy-metal-binding
H2787_RS04165	COG1538	Outer membrane efflux protein
H2787_RS04175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2787_RS04180	COG0671	phosphoesterase, PA-phosphatase related
H2787_RS04210	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H2787_RS04225	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H2787_RS04225	COG1648	precorrin-2 dehydrogenase activity
H2787_RS04230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H2787_RS04235	COG1733	regulation of RNA biosynthetic process
H2787_RS04245	COG0531	amino acid
H2787_RS04260	COG0321	lipoyl(octanoyl) transferase activity
H2787_RS04265	COG2921	Belongs to the UPF0250 family
H2787_RS04300	COG2009	succinate dehydrogenase
H2787_RS04305	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H2787_RS04310	COG1053	succinate dehydrogenase
H2787_RS04315	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H2787_RS04340	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2787_RS04360	COG2354	Protein conserved in bacteria
H2787_RS04365	COG2321	neutral zinc metallopeptidase
H2787_RS04390	COG2843	Capsule synthesis protein
H2787_RS04400	COG3293	Transposase
H2787_RS04410	COG0589	response to stress
H2787_RS04455	COG0505	Belongs to the CarA family
H2787_RS04480	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H2787_RS04485	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H2787_RS04535	COG0477	Major facilitator Superfamily
H2787_RS04545	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H2787_RS04560	COG1597	lipid kinase activity
H2787_RS04565	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H2787_RS04585	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2787_RS04590	COG0584	glycerophosphoryl diester phosphodiesterase
H2787_RS04605	COG2963	transposase activity
H2787_RS04615	COG4372	Transposase
H2787_RS04630	COG0741	lytic transglycosylase activity
H2787_RS04660	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H2787_RS04720	COG2963	transposase activity
H2787_RS04730	COG4372	Transposase
H2787_RS04755	COG0778	Nitroreductase
H2787_RS04770	COG1929	Belongs to the glycerate kinase type-1 family
H2787_RS04775	COG0243	molybdopterin cofactor binding
H2787_RS04780	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H2787_RS04785	COG3339	Conserved Protein
H2787_RS04795	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H2787_RS04810	COG1115	amino acid carrier protein
H2787_RS04815	COG1113	amino acid transport
H2787_RS04825	COG0019	diaminopimelate decarboxylase activity
H2787_RS04840	COG2267	carboxylic ester hydrolase activity
H2787_RS04845	COG1280	lysine exporter protein (LysE YggA)
H2787_RS04850	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H2787_RS04880	COG0463	Glycosyl transferase, family 2
H2787_RS04900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2787_RS04935	COG4591	ABC-type transport system involved in lipoprotein release permease component
H2787_RS04940	COG1136	(ABC) transporter
H2787_RS04955	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H2787_RS04955	COG0616	signal peptide processing
H2787_RS04960	COG0596	Alpha beta hydrolase
H2787_RS04965	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H2787_RS04975	COG0628	permease
H2787_RS04980	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
H2787_RS05015	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2787_RS05035	COG0823	Involved in the tonB-independent uptake of proteins
H2787_RS05055	COG0824	Thioesterase
H2787_RS05060	COG1473	amidohydrolase
H2787_RS05080	COG0047	phosphoribosylformylglycinamidine synthase activity
H2787_RS05080	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H2787_RS05085	COG2814	Major facilitator Superfamily
H2787_RS05095	COG1024	Enoyl-CoA hydratase
H2787_RS05100	COG1056	cytidyltransferase-related domain
H2787_RS05100	COG1051	belongs to the nudix hydrolase family
H2787_RS05110	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H2787_RS05125	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H2787_RS05145	COG0583	DNA-binding transcription factor activity
H2787_RS05150	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H2787_RS05155	COG4208	sulfate ABC transporter
H2787_RS05160	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H2787_RS05170	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H2787_RS05175	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H2787_RS05180	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H2787_RS05200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2787_RS05220	COG0681	Belongs to the peptidase S26 family
H2787_RS05235	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H2787_RS05245	COG1381	Involved in DNA repair and RecF pathway recombination
H2787_RS05250	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H2787_RS05260	COG4221	oxidoreductase activity
H2787_RS05290	COG0436	Aminotransferase
H2787_RS05315	COG0556	nucleotide-excision repair
H2787_RS05345	COG4372	Transposase
H2787_RS05355	COG2963	transposase activity
H2787_RS05390	COG2070	2-Nitropropane dioxygenase
H2787_RS05430	COG0415	Belongs to the DNA photolyase family
H2787_RS05440	COG1252	NADH dehydrogenase
H2787_RS05445	COG1686	Belongs to the peptidase S11 family
H2787_RS05465	COG1187	pseudouridine synthase activity
H2787_RS05490	COG0477	Major facilitator Superfamily
H2787_RS05495	COG0583	DNA-binding transcription factor activity
H2787_RS05500	COG1823	symporter activity
H2787_RS05510	COG0612	Peptidase, M16
H2787_RS05535	COG0352	thiamine-phosphate diphosphorylase activity
H2787_RS05570	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2787_RS05600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H2787_RS05605	COG0076	glutamate decarboxylase activity
H2787_RS05640	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H2787_RS05645	COG0573	inorganic phosphate transmembrane transporter activity
H2787_RS05655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H2787_RS05660	COG0616	signal peptide processing
H2787_RS05695	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H2787_RS05710	COG1686	Belongs to the peptidase S11 family
H2787_RS05735	COG0583	DNA-binding transcription factor activity
H2787_RS05740	COG2433	Pfam Transposase IS66
H2787_RS05755	COG1067	ATP-dependent peptidase activity
H2787_RS05780	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H2787_RS05800	COG1966	Carbon starvation protein
H2787_RS05805	COG2879	small protein
H2787_RS05815	COG0582	viral genome integration into host DNA
H2787_RS05840	COG3293	Transposase
H2787_RS05875	COG1741	Belongs to the pirin family
H2787_RS05885	COG2964	Protein conserved in bacteria
H2787_RS05905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2787_RS05910	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H2787_RS05915	COG4605	iron ion homeostasis
H2787_RS05920	COG4604	ABC transporter, ATP-binding protein
H2787_RS05925	COG4607	ABC-type enterochelin transport system periplasmic component
H2787_RS05930	COG4774	siderophore transport
H2787_RS05940	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H2787_RS05945	COG1021	2,3-dihydroxybenzoate-AMP ligase
H2787_RS05950	COG1535	isochorismatase
H2787_RS05950	COG3433	isochorismatase activity
H2787_RS05975	COG3293	Transposase
H2787_RS05985	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H2787_RS06010	COG3739	integral membrane protein
H2787_RS06040	COG0302	gtp cyclohydrolase
H2787_RS06050	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H2787_RS06105	COG0512	Glutamine amidotransferase of anthranilate synthase
H2787_RS06120	COG0174	glutamine synthetase
H2787_RS06130	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H2787_RS06165	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H2787_RS06170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H2787_RS06175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H2787_RS06195	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H2787_RS06200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H2787_RS06205	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H2787_RS06220	COG1960	acyl-CoA dehydrogenase activity
H2787_RS06225	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H2787_RS06230	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2787_RS06240	COG2223	nitrite transmembrane transporter activity
H2787_RS06250	COG0024	Methionine aminopeptidase
H2787_RS06255	COG0052	Belongs to the universal ribosomal protein uS2 family
H2787_RS06270	COG2207	Transcriptional regulator
H2787_RS06295	COG2951	lytic endotransglycosylase activity
H2787_RS06300	COG0772	Belongs to the SEDS family
H2787_RS06315	COG0842	Transport permease protein
H2787_RS06320	COG1131	(ABC) transporter
H2787_RS06325	COG0582	viral genome integration into host DNA
H2787_RS06435	COG0305	Participates in initiation and elongation during chromosome replication
H2787_RS06600	COG1598	PFAM Uncharacterised protein family UPF0150
H2787_RS06695	COG2433	Pfam Transposase IS66
H2787_RS06735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2787_RS06750	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H2787_RS06755	COG0826	peptidase U32
H2787_RS06760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2787_RS06775	COG1720	tRNA m6t6A37 methyltransferase activity
H2787_RS06785	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H2787_RS06800	COG0642	Histidine kinase
H2787_RS06810	COG0494	nUDIX hydrolase
H2787_RS06820	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H2787_RS06825	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H2787_RS06830	COG3139	Protein of unknown function (DUF1315)
H2787_RS06835	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H2787_RS06840	COG1301	dicarboxylic acid transport
H2787_RS06845	COG1960	acyl-CoA dehydrogenase activity
H2787_RS06870	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H2787_RS06880	COG2195	Cleaves the N-terminal amino acid of tripeptides
H2787_RS06955	COG2363	Small membrane protein
H2787_RS06975	COG0513	Belongs to the DEAD box helicase family
H2787_RS06985	COG0778	Nitroreductase
H2787_RS07015	COG1286	toxin biosynthetic process
H2787_RS07040	COG4783	chaperone-mediated protein folding
H2787_RS07045	COG1610	YqeY-like protein
H2787_RS07075	COG0515	serine threonine protein kinase
H2787_RS07105	COG1301	dicarboxylic acid transport
H2787_RS07115	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2787_RS07120	COG2011	ABC-type metal ion transport system permease component
H2787_RS07125	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H2787_RS07130	COG1464	Belongs to the NlpA lipoprotein family
H2787_RS07135	COG0151	Belongs to the GarS family
H2787_RS07140	COG0138	bifunctional purine biosynthesis protein purh
H2787_RS07145	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H2787_RS07180	COG2308	Evidence 4 Homologs of previously reported genes of
H2787_RS07190	COG1305	Transglutaminase-like
H2787_RS07200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H2787_RS07205	COG0305	Participates in initiation and elongation during chromosome replication
H2787_RS07230	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H2787_RS07240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H2787_RS07245	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H2787_RS07270	COG0726	polysaccharide deacetylase
H2787_RS07270	COG1649	PFAM Uncharacterised BCR, COG1649
H2787_RS07275	COG1215	transferase activity, transferring glycosyl groups
H2787_RS07280	COG3658	cytochrome
H2787_RS07290	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2787_RS07305	COG0583	DNA-binding transcription factor activity
H2787_RS07335	COG1960	acyl-CoA dehydrogenase activity
H2787_RS07355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2787_RS07380	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H2787_RS07385	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H2787_RS07390	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H2787_RS07395	COG2205	protein histidine kinase activity
H2787_RS07400	COG0745	RESPONSE REGULATOR receiver
H2787_RS07405	COG0174	glutamine synthetase
H2787_RS07425	COG0729	surface antigen
H2787_RS07460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2787_RS07475	COG2963	transposase activity
H2787_RS07485	COG4372	Transposase
H2787_RS07495	COG0583	DNA-binding transcription factor activity
H2787_RS07510	COG1187	pseudouridine synthase activity
H2787_RS07530	COG0802	atpase or kinase
H2787_RS07535	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H2787_RS07545	COG1923	regulation of RNA biosynthetic process
H2787_RS07550	COG0697	spore germination
H2787_RS07575	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H2787_RS07580	COG0519	Catalyzes the synthesis of GMP from XMP
H2787_RS07580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H2787_RS07585	COG4302	ethanolamine ammonia-lyase activity
H2787_RS07590	COG4303	Ethanolamine ammonia lyase large subunit
H2787_RS07595	COG0531	amino acid
H2787_RS07625	COG1454	alcohol dehydrogenase
H2787_RS07630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2787_RS07640	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
H2787_RS07660	COG0308	aminopeptidase N
H2787_RS07700	COG1605	Chorismate mutase
H2787_RS07720	COG0668	transmembrane transport
H2787_RS07755	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H2787_RS07760	COG0583	DNA-binding transcription factor activity
H2787_RS07770	COG0183	Belongs to the thiolase family
H2787_RS07780	COG2030	dehydratase
H2787_RS07785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2787_RS07800	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H2787_RS07810	COG0824	Thioesterase
H2787_RS07815	COG2963	transposase activity
H2787_RS07825	COG4372	Transposase
H2787_RS07840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H2787_RS07875	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS07885	COG2814	Major facilitator Superfamily
H2787_RS07895	COG0439	Biotin carboxylase
H2787_RS07900	COG0511	ligase activity, forming carbon-carbon bonds
H2787_RS07915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2787_RS07915	COG1116	anion transmembrane transporter activity
H2787_RS07920	COG0745	RESPONSE REGULATOR receiver
H2787_RS07930	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2787_RS07930	COG2146	nitrite reductase [NAD(P)H] activity
H2787_RS07935	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2787_RS07940	COG0243	molybdopterin cofactor binding
H2787_RS07955	COG3293	Transposase
H2787_RS07965	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H2787_RS07980	COG0521	Mo-molybdopterin cofactor biosynthetic process
H2787_RS07980	COG0315	cyclic pyranopterin monophosphate synthase activity
H2787_RS07985	COG0303	'Molybdopterin
H2787_RS08015	COG0697	spore germination
H2787_RS08035	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H2787_RS08040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H2787_RS08100	COG2204	response regulator
H2787_RS08105	COG3852	Histidine kinase
H2787_RS08125	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H2787_RS08130	COG0575	Belongs to the CDS family
H2787_RS08145	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H2787_RS08165	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2787_RS08180	COG2137	regulation of response to DNA damage stimulus
H2787_RS08190	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H2787_RS08195	COG1011	Hydrolase
H2787_RS08210	COG2963	transposase activity
H2787_RS08235	COG1522	sequence-specific DNA binding
H2787_RS08245	COG1113	amino acid transport
H2787_RS08265	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS08285	COG3293	Transposase
H2787_RS08295	COG0659	secondary active sulfate transmembrane transporter activity
H2787_RS08300	COG2963	transposase activity
H2787_RS08310	COG4372	Transposase
H2787_RS08315	COG2135	peptidase activity
H2787_RS08355	COG3293	Transposase
H2787_RS08390	COG0024	Methionine aminopeptidase
H2787_RS08395	COG0583	DNA-binding transcription factor activity
H2787_RS08405	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H2787_RS08410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H2787_RS08415	COG0516	GMP reductase activity
H2787_RS08415	COG0517	IMP dehydrogenase activity
H2787_RS08440	COG0552	protein localization to endoplasmic reticulum
H2787_RS08450	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H2787_RS08460	COG4890	Cyd operon protein YbgT
H2787_RS08465	COG1294	oxidase, subunit
H2787_RS08480	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS08485	COG1585	Membrane protein implicated in regulation of membrane protease activity
H2787_RS08495	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H2787_RS08500	COG4774	siderophore transport
H2787_RS08515	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H2787_RS08520	COG0569	domain protein
H2787_RS08525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H2787_RS08555	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H2787_RS08560	COG0542	response to heat
H2787_RS08585	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2787_RS08585	COG1902	pentaerythritol trinitrate reductase activity
H2787_RS08655	COG3293	Transposase
H2787_RS08665	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H2787_RS08675	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2787_RS08680	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2787_RS08685	COG0183	Belongs to the thiolase family
H2787_RS08690	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H2787_RS08695	COG0596	Alpha beta hydrolase
H2787_RS08700	COG2271	Major facilitator Superfamily
H2787_RS08705	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H2787_RS08710	COG3485	protocatechuate 3,4-dioxygenase
H2787_RS08715	COG3485	protocatechuate 3,4-dioxygenase
H2787_RS08720	COG0710	3-dehydroquinate dehydratase activity
H2787_RS08725	COG3420	alginic acid biosynthetic process
H2787_RS08730	COG3659	wide pore channel activity
H2787_RS08750	COG2391	methyltransferase activity
H2787_RS08765	COG1414	Transcriptional regulator
H2787_RS08770	COG0583	DNA-binding transcription factor activity
H2787_RS08775	COG1960	acyl-CoA dehydrogenase activity
H2787_RS08800	COG2814	Major facilitator Superfamily
H2787_RS08810	COG0154	amidase activity
H2787_RS08830	COG4638	Rieske (2fe-2S)
H2787_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
H2787_RS08850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2787_RS08860	COG3733	amine oxidase
H2787_RS08870	COG1012	belongs to the aldehyde dehydrogenase family
H2787_RS08880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2787_RS08900	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H2787_RS08905	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H2787_RS08915	COG4829	muconolactone delta-isomerase
H2787_RS08920	COG4948	Mandelate Racemase Muconate Lactonizing
H2787_RS08925	COG0583	DNA-binding transcription factor activity
H2787_RS08935	COG2186	Transcriptional regulator
H2787_RS08950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2787_RS08955	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2787_RS09045	COG2963	transposase activity
H2787_RS09055	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H2787_RS09070	COG0753	catalase activity
H2787_RS09085	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H2787_RS09145	COG2433	Pfam Transposase IS66
H2787_RS09170	COG1535	isochorismatase
H2787_RS09170	COG3433	isochorismatase activity
H2787_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
H2787_RS09180	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H2787_RS09185	COG4149	molybdate abc transporter
H2787_RS09190	COG0725	ABC transporter, periplasmic molybdate-binding protein
H2787_RS09205	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H2787_RS09210	COG0543	2 iron, 2 sulfur cluster binding
H2787_RS09210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2787_RS09230	COG0583	DNA-binding transcription factor activity
H2787_RS09235	COG3293	Transposase
H2787_RS09250	COG2031	fatty acid transporter
H2787_RS09255	COG0183	Belongs to the thiolase family
H2787_RS09260	COG0583	DNA-binding transcription factor activity
H2787_RS09265	COG0583	DNA-binding transcription factor activity
H2787_RS09305	COG1027	Aspartate ammonia-lyase
H2787_RS09315	COG0477	Major facilitator Superfamily
H2787_RS09335	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2787_RS09345	COG4521	taurine ABC transporter
H2787_RS09360	COG2188	Transcriptional regulator
H2787_RS09370	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H2787_RS09375	COG1733	regulation of RNA biosynthetic process
H2787_RS09380	COG3708	Transcriptional regulator
H2787_RS09380	COG2207	Transcriptional regulator
H2787_RS09395	COG0730	response to heat
H2787_RS09405	COG3453	Protein conserved in bacteria
H2787_RS09405	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2787_RS09415	COG3781	membrane
H2787_RS09420	COG1063	alcohol dehydrogenase
H2787_RS09430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H2787_RS09445	COG0022	dehydrogenase e1 component
H2787_RS09450	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H2787_RS09455	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H2787_RS09470	COG3706	GGDEF domain
H2787_RS09485	COG0133	tryptophan synthase activity
H2787_RS09495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H2787_RS09515	COG2963	transposase activity
H2787_RS09525	COG4372	Transposase
H2787_RS09560	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H2787_RS09615	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS09645	COG0842	Transport permease protein
H2787_RS09650	COG0842	Transport permease protein
H2787_RS09655	COG1131	(ABC) transporter
H2787_RS09670	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H2787_RS09675	COG4773	Receptor
H2787_RS09705	COG0730	response to heat
H2787_RS09710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H2787_RS09730	COG0406	alpha-ribazole phosphatase activity
H2787_RS09750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H2787_RS09790	COG1960	acyl-CoA dehydrogenase activity
H2787_RS09795	COG1960	acyl-CoA dehydrogenase activity
H2787_RS09800	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H2787_RS09810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2787_RS09815	COG0776	regulation of translation
H2787_RS09840	COG0822	iron-sulfur transferase activity
H2787_RS09845	COG0316	Belongs to the HesB IscA family
H2787_RS09875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H2787_RS09895	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H2787_RS09900	COG0702	epimerase
H2787_RS09945	COG0339	signal peptide processing
H2787_RS09975	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS10025	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H2787_RS10030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H2787_RS10060	COG0776	regulation of translation
H2787_RS10125	COG0084	hydrolase, TatD family'
H2787_RS10145	COG1663	tetraacyldisaccharide 4'-kinase activity
H2787_RS10150	COG1132	(ABC) transporter
H2787_RS10160	COG0811	peptide transport
H2787_RS10165	COG1475	DNA binding
H2787_RS10170	COG1192	Involved in chromosome partitioning
H2787_RS10180	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H2787_RS10195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H2787_RS10200	COG0191	fructose-bisphosphate aldolase activity
H2787_RS10220	COG0424	maF-like protein
H2787_RS10225	COG2850	peptidyl-arginine hydroxylation
H2787_RS10245	COG3293	Transposase
H2787_RS10250	COG0640	Transcriptional regulator
H2787_RS10265	COG3619	membrane
H2787_RS10270	COG3122	Protein conserved in bacteria
H2787_RS10275	COG3328	transposase activity
H2787_RS10280	COG1132	(ABC) transporter
H2787_RS10315	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H2787_RS10325	COG4372	Transposase
H2787_RS10370	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H2787_RS10385	COG3698	Phosphodiester glycosidase
H2787_RS10395	COG2353	YceI-like domain
H2787_RS10405	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H2787_RS10450	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H2787_RS10450	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H2787_RS10500	COG0697	spore germination
H2787_RS10510	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H2787_RS10520	COG0583	DNA-binding transcription factor activity
H2787_RS10565	COG1464	Belongs to the NlpA lipoprotein family
H2787_RS10575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H2787_RS10580	COG2011	ABC-type metal ion transport system permease component
H2787_RS10585	COG0012	GTP binding
H2787_RS10610	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H2787_RS10660	COG0386	Belongs to the glutathione peroxidase family
H2787_RS10670	COG0436	Aminotransferase
H2787_RS10740	COG3634	alkyl hydroperoxide reductase activity
H2787_RS10755	COG0583	DNA-binding transcription factor activity
H2787_RS10760	COG0798	PFAM Bile acid sodium symporter
H2787_RS10765	COG0640	Transcriptional regulator
H2787_RS10795	COG0583	DNA-binding transcription factor activity
H2787_RS10815	COG1271	oxidase subunit
H2787_RS10820	COG1294	oxidase, subunit
H2787_RS10830	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2787_RS10850	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H2787_RS10885	COG3052	prosthetic group binding
H2787_RS10900	COG0583	DNA-binding transcription factor activity
H2787_RS10910	COG2814	Major facilitator Superfamily
H2787_RS10915	COG0300	oxidoreductase activity
H2787_RS10940	COG1346	cytolysis
H2787_RS10950	COG0583	DNA-binding transcription factor activity
H2787_RS10970	COG0625	glutathione transferase activity
H2787_RS10975	COG0583	DNA-binding transcription factor activity
H2787_RS11005	COG1045	serine acetyltransferase
H2787_RS11010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H2787_RS11015	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H2787_RS11030	COG2433	Pfam Transposase IS66
H2787_RS11035	COG1280	lysine exporter protein (LysE YggA)
H2787_RS11045	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2787_RS11050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H2787_RS11055	COG1126	abc transporter atp-binding protein
H2787_RS11060	COG0765	amino acid transport
H2787_RS11065	COG0765	amino acid transport
H2787_RS11075	COG3293	Transposase
H2787_RS11090	COG2205	protein histidine kinase activity
H2787_RS11090	COG0784	Response regulator, receiver
H2787_RS11110	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H2787_RS11220	COG0789	Transcriptional regulator
H2787_RS11235	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS11280	COG1522	sequence-specific DNA binding
H2787_RS11295	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H2787_RS11305	COG4122	O-methyltransferase activity
H2787_RS11335	COG1538	Outer membrane efflux protein
H2787_RS11340	COG1137	ATPase activity
H2787_RS11345	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H2787_RS11355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H2787_RS11395	COG1278	Cold shock
H2787_RS11405	COG3293	Transposase
H2787_RS11435	COG1570	exodeoxyribonuclease VII activity
H2787_RS11485	COG0583	DNA-binding transcription factor activity
H2787_RS11490	COG4638	Rieske (2fe-2S)
H2787_RS11500	COG0543	2 iron, 2 sulfur cluster binding
H2787_RS11500	COG0633	Ferredoxin
H2787_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
H2787_RS11535	COG2814	Major facilitator Superfamily
H2787_RS11550	COG1643	Atp-dependent helicase
H2787_RS11555	COG0450	alkyl hydroperoxide reductase
H2787_RS11565	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H2787_RS11580	COG3634	alkyl hydroperoxide reductase activity
H2787_RS11600	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H2787_RS11605	COG0625	glutathione transferase activity
H2787_RS11615	COG2885	chlorophyll binding
H2787_RS11660	COG3328	transposase activity
H2787_RS11670	COG1765	OsmC-like protein
H2787_RS11685	COG0667	Aldo Keto reductase
H2787_RS11700	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H2787_RS11710	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H2787_RS11720	COG0582	viral genome integration into host DNA
H2787_RS11845	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS11860	COG0527	aspartate kinase activity
H2787_RS11870	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H2787_RS11880	COG3038	cytochrome b561
H2787_RS11895	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H2787_RS11900	COG2252	PERMEase
H2787_RS11970	COG3706	GGDEF domain
H2787_RS11970	COG4251	negative regulation of phosphorylation
H2787_RS11970	COG2203	Gaf domain
H2787_RS11970	COG5001	Diguanylate cyclase
H2787_RS11980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H2787_RS12015	COG4172	Belongs to the ABC transporter superfamily
H2787_RS12020	COG4239	(ABC) transporter, permease
H2787_RS12025	COG4174	ABC transporter (Permease)
H2787_RS12035	COG0741	lytic transglycosylase activity
H2787_RS12035	COG1388	LysM domain
H2787_RS12040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H2787_RS12060	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS12090	COG0583	DNA-binding transcription factor activity
H2787_RS12095	COG1279	arginine transmembrane transporter activity
H2787_RS12115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2787_RS12120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2787_RS12125	COG0006	proline dipeptidase activity
H2787_RS12155	COG3293	Transposase
H2787_RS12170	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H2787_RS12195	COG3384	dioxygenase
H2787_RS12205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H2787_RS12210	COG2878	Part of a membrane complex involved in electron transport
H2787_RS12215	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H2787_RS12240	COG0768	penicillin binding
H2787_RS12245	COG0742	ribosomal rna small subunit methyltransferase
H2787_RS12260	COG0830	nickel cation binding
H2787_RS12270	COG0804	urea catabolic process
H2787_RS12320	COG1253	flavin adenine dinucleotide binding
H2787_RS12325	COG3293	Transposase
H2787_RS12335	COG2851	Citrate transporter
H2787_RS12390	COG1773	rubredoxin
H2787_RS12395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H2787_RS12405	COG0583	DNA-binding transcription factor activity
H2787_RS12435	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H2787_RS12440	COG4181	ATPase activity
H2787_RS12500	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H2787_RS12525	COG3293	Transposase
H2787_RS12535	COG3958	Transketolase
H2787_RS12540	COG3959	Transketolase, thiamine diphosphate binding domain
H2787_RS12545	COG2271	Major facilitator Superfamily
H2787_RS12550	COG1028	Short-chain dehydrogenase reductase Sdr
H2787_RS12555	COG0583	DNA-binding transcription factor activity
H2787_RS12565	COG3293	Transposase
H2787_RS12575	COG2223	nitrite transmembrane transporter activity
H2787_RS12580	COG2207	Transcriptional regulator
H2787_RS12600	COG0242	peptide deformylase activity
H2787_RS12605	COG0477	Major facilitator Superfamily
H2787_RS12615	COG0028	Belongs to the TPP enzyme family
H2787_RS12630	COG1028	Short-chain dehydrogenase reductase Sdr
H2787_RS12635	COG2267	carboxylic ester hydrolase activity
H2787_RS12650	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2787_RS12660	COG1028	Short-chain dehydrogenase reductase Sdr
H2787_RS12680	COG1024	Enoyl-CoA hydratase
H2787_RS12690	COG1215	transferase activity, transferring glycosyl groups
H2787_RS12695	COG0726	polysaccharide deacetylase
H2787_RS12695	COG1649	PFAM Uncharacterised BCR, COG1649
H2787_RS12705	COG4681	YaeQ
H2787_RS12725	COG0523	cobalamin synthesis protein
H2787_RS12735	COG1607	acyl-coa hydrolase
H2787_RS12745	COG3177	Filamentation induced by cAMP protein fic
H2787_RS12750	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H2787_RS12835	COG4372	Transposase
H2787_RS12845	COG2963	transposase activity
H2787_RS12865	COG0582	viral genome integration into host DNA
H2787_RS12875	COG0405	Gamma-glutamyltransferase
H2787_RS12880	COG2814	Major facilitator Superfamily
H2787_RS12890	COG2050	protein possibly involved in aromatic compounds catabolism
H2787_RS12905	COG1090	epimerase
H2787_RS12925	COG0420	3'-5' exonuclease activity
H2787_RS12950	COG0735	belongs to the Fur family
H2787_RS12955	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H2787_RS12985	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS13005	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2787_RS13015	COG0210	DNA helicase
H2787_RS13020	COG2885	chlorophyll binding
H2787_RS13025	COG0204	Acyl-transferase
H2787_RS13040	COG2894	cell division
H2787_RS13055	COG1280	lysine exporter protein (LysE YggA)
H2787_RS13060	COG1674	ftsk spoiiie
H2787_RS13060	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H2787_RS13065	COG0492	ferredoxin-NADP+ reductase activity
H2787_RS13070	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H2787_RS13080	COG0456	acetyltransferase
H2787_RS13140	COG1981	membrane
H2787_RS13155	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2787_RS13155	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H2787_RS13210	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H2787_RS13235	COG0564	pseudouridine synthase activity
H2787_RS13245	COG0358	DNA primase activity
H2787_RS13260	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H2787_RS13290	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H2787_RS13330	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H2787_RS13340	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H2787_RS13340	COG0352	thiamine-phosphate diphosphorylase activity
H2787_RS13340	COG0351	phosphomethylpyrimidine kinase
H2787_RS13345	COG1652	LysM domain
H2787_RS13370	COG1399	metal-binding, possibly nucleic acid-binding protein
H2787_RS13375	COG3101	peptidyl-lysine hydroxylation
H2787_RS13380	COG0009	L-threonylcarbamoyladenylate synthase
H2787_RS13385	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H2787_RS13390	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H2787_RS13400	COG3293	Transposase
H2787_RS13410	COG4106	trans-aconitate 2-methyltransferase activity
H2787_RS13425	COG0596	Alpha beta hydrolase
H2787_RS13425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2787_RS13425	COG2226	methyltransferase
H2787_RS13435	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS13445	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H2787_RS13450	COG2223	nitrite transmembrane transporter activity
H2787_RS13470	COG1196	nuclear chromosome segregation
H2787_RS13480	COG0730	response to heat
H2787_RS13495	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H2787_RS13505	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2787_RS13520	COG3328	transposase activity
H2787_RS13570	COG0489	protein tyrosine kinase activity
H2787_RS13580	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2787_RS13580	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2787_RS13590	COG3293	Transposase
H2787_RS13615	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H2787_RS13620	COG2081	HI0933 family
H2787_RS13630	COG0668	transmembrane transport
H2787_RS13650	COG0583	DNA-binding transcription factor activity
H2787_RS13670	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H2787_RS13675	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H2787_RS13705	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H2787_RS13730	COG3706	GGDEF domain
H2787_RS13745	COG0745	RESPONSE REGULATOR receiver
H2787_RS13765	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H2787_RS13785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H2787_RS13800	COG0583	DNA-binding transcription factor activity
H2787_RS13850	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H2787_RS13860	COG1960	acyl-CoA dehydrogenase activity
H2787_RS13865	COG0583	DNA-binding transcription factor activity
H2787_RS13870	COG1063	alcohol dehydrogenase
H2787_RS13900	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H2787_RS13905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H2787_RS13910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2787_RS13930	COG2132	Multicopper oxidase
H2787_RS13940	COG0561	phosphatase activity
H2787_RS13945	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H2787_RS13955	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H2787_RS13970	COG1214	PFAM Peptidase M22, glycoprotease
H2787_RS13995	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS14015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H2787_RS14020	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H2787_RS14025	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H2787_RS14085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H2787_RS14095	COG1846	Transcriptional regulator
H2787_RS14100	COG1764	response to oxidative stress
H2787_RS14140	COG0037	tRNA processing
H2787_RS14150	COG0248	Ppx GppA phosphatase
H2787_RS14180	COG0072	phenylalanine-tRNA ligase activity
H2787_RS14220	COG1238	metal cluster binding
H2787_RS14225	COG0625	glutathione transferase activity
H2787_RS14240	COG0318	PFAM AMP-dependent synthetase and ligase
H2787_RS14245	COG3028	Belongs to the UPF0307 family
H2787_RS14250	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H2787_RS14270	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H2787_RS14275	COG0617	tRNA 3'-terminal CCA addition
H2787_RS14280	COG1555	photosystem II stabilization
H2787_RS14285	COG3956	TIGRFAM MazG family protein
H2787_RS14295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H2787_RS14315	COG5002	protein histidine kinase activity
H2787_RS14315	COG0784	Response regulator, receiver
H2787_RS14315	COG2205	protein histidine kinase activity
H2787_RS14320	COG1024	Enoyl-CoA hydratase
H2787_RS14325	COG2084	Dehydrogenase
H2787_RS14330	COG3622	Belongs to the hyi family
H2787_RS14360	COG0697	spore germination
H2787_RS14370	COG2814	Major facilitator Superfamily
H2787_RS14375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H2787_RS14385	COG0583	DNA-binding transcription factor activity
H2787_RS14395	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H2787_RS14405	COG0084	hydrolase, TatD family'
H2787_RS14420	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H2787_RS14460	COG0440	acetolactate synthase activity
H2787_RS14465	COG0028	Belongs to the TPP enzyme family
H2787_RS14490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2787_RS14495	COG0577	efflux transmembrane transporter activity
H2787_RS14495	COG1136	(ABC) transporter
H2787_RS14500	COG1538	Outer membrane efflux protein
H2787_RS14515	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H2787_RS14520	COG1162	GTPase activity
H2787_RS14530	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H2787_RS14570	COG1426	Protein conserved in bacteria
H2787_RS14605	COG0793	Belongs to the peptidase S41A family
H2787_RS14620	COG2267	carboxylic ester hydrolase activity
H2787_RS14630	COG1012	belongs to the aldehyde dehydrogenase family
H2787_RS14635	COG3265	gluconokinase activity
H2787_RS14645	COG0800	Aldolase
H2787_RS14655	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H2787_RS14660	COG0280	phosphate acetyltransferase
H2787_RS14660	COG0857	belongs to the CobB CobQ family
H2787_RS14665	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H2787_RS14665	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H2787_RS14675	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS14695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H2787_RS14705	COG1061	Type III restriction enzyme res subunit
H2787_RS14710	COG1002	Type II restriction enzyme, methylase subunits
H2787_RS14725	COG4584	PFAM Integrase catalytic
H2787_RS14730	COG1484	DNA-dependent DNA replication
H2787_RS14740	COG0740	serine-type endopeptidase activity
H2787_RS14750	COG4774	siderophore transport
H2787_RS14760	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H2787_RS14770	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H2787_RS14770	COG2813	Specifically methylates the guanine in position
H2787_RS14810	COG4372	Transposase
H2787_RS14820	COG2963	transposase activity
H2787_RS14885	COG0788	formyltetrahydrofolate deformylase activity
H2787_RS14910	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2787_RS14910	COG4651	solute:proton antiporter activity
H2787_RS14930	COG0724	RNA recognition motif
H2787_RS14935	COG0210	DNA helicase
H2787_RS14960	COG1733	regulation of RNA biosynthetic process
H2787_RS14970	COG2900	Belongs to the SlyX family
H2787_RS14975	COG0488	(ABC) transporter
H2787_RS14980	COG1280	lysine exporter protein (LysE YggA)
H2787_RS14985	COG1560	Kdo2-lipid A biosynthetic process
H2787_RS14995	COG1301	dicarboxylic acid transport
H2787_RS15055	COG0473	3-isopropylmalate dehydrogenase activity
H2787_RS15115	COG0583	DNA-binding transcription factor activity
H2787_RS15125	COG0625	glutathione transferase activity
H2787_RS15130	COG2378	regulation of single-species biofilm formation
H2787_RS15135	COG0546	phosphoglycolate phosphatase activity
H2787_RS15145	COG1530	ribonuclease E activity
H2787_RS15160	COG0318	PFAM AMP-dependent synthetase and ligase
H2787_RS15180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H2787_RS15190	COG0534	Mate efflux family protein
H2787_RS15205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H2787_RS15230	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H2787_RS15230	COG0493	'glutamate synthase
H2787_RS15240	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H2787_RS15245	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H2787_RS15260	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H2787_RS15270	COG0644	oxidoreductase
H2787_RS15270	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H2787_RS15280	COG0425	Belongs to the sulfur carrier protein TusA family
H2787_RS15285	COG4535	Mg2 and Co2 transporter CorC
H2787_RS15295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H2787_RS15315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H2787_RS15320	COG0475	glutathione-regulated potassium exporter activity
H2787_RS15320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H2787_RS15335	COG0484	heat shock protein binding
H2787_RS15340	COG0789	Transcriptional regulator
H2787_RS15345	COG0598	Magnesium transport protein CorA
H2787_RS15360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H2787_RS15365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H2787_RS15370	COG1074	ATP-dependent DNA helicase activity
H2787_RS15375	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H2787_RS15395	COG2226	methyltransferase
H2787_RS15410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H2787_RS15415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H2787_RS15430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H2787_RS15430	COG2111	Na H antiporter
H2787_RS15435	COG1006	Multisubunit Na H antiporter MnhC subunit
H2787_RS15440	COG0651	ATP synthesis coupled electron transport
H2787_RS15445	COG1863	multisubunit Na H antiporter MnhE subunit
H2787_RS15450	COG2212	antiporter activity
H2787_RS15455	COG1320	monovalent cation:proton antiporter activity
H2787_RS15470	COG0195	Participates in both transcription termination and antitermination
H2787_RS15520	COG0237	dephospho-CoA kinase activity
H2787_RS15530	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H2787_RS15545	COG0497	DNA recombination
H2787_RS15555	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H2787_RS15585	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H2787_RS15585	COG2169	Transcriptional regulator
H2787_RS15590	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H2787_RS15600	COG3293	Transposase
H2787_RS15655	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H2787_RS15665	COG3328	transposase activity
H2787_RS15680	COG0326	Molecular chaperone. Has ATPase activity
H2787_RS15695	COG2056	Na+-H+ antiporter family
H2787_RS15700	COG0596	Alpha beta hydrolase
H2787_RS15795	COG0546	phosphoglycolate phosphatase activity
H2787_RS15800	COG1716	ATPase activity
H2787_RS15845	COG0181	hydroxymethylbilane synthase activity
H2787_RS15855	COG3275	phosphorelay sensor kinase activity
H2787_RS15875	COG1538	Outer membrane efflux protein
H2787_RS15880	COG0697	spore germination
H2787_RS15905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H2787_RS15910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H2787_RS15915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H2787_RS15925	COG0772	Belongs to the SEDS family
H2787_RS15950	COG4974	Belongs to the 'phage' integrase family
H2787_RS15955	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2787_RS15965	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H2787_RS15975	COG2197	response regulator
H2787_RS16000	COG0793	Belongs to the peptidase S41A family
H2787_RS16005	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H2787_RS16010	COG0795	lipopolysaccharide-transporting ATPase activity
H2787_RS16085	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2787_RS16085	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H2787_RS16095	COG0004	ammonium transporteR
H2787_RS16100	COG0347	Belongs to the P(II) protein family
H2787_RS16110	COG0606	chelatase, subunit chli
H2787_RS16180	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H2787_RS16185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H2787_RS16195	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H2787_RS16210	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H2787_RS16225	COG0318	PFAM AMP-dependent synthetase and ligase
H2787_RS16235	COG0477	Major facilitator Superfamily
H2787_RS16240	COG2860	membrane
H2787_RS16250	COG1253	flavin adenine dinucleotide binding
H2787_RS16260	COG0477	Major facilitator Superfamily
H2787_RS16270	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H2787_RS16320	COG0655	NAD(P)H dehydrogenase (quinone) activity
H2787_RS16330	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H2787_RS16400	COG0758	DNA mediated transformation
H2787_RS16410	COG0697	spore germination
H2787_RS16415	COG3328	transposase activity
H2787_RS16425	COG0386	Belongs to the glutathione peroxidase family
H2787_RS16490	COG1121	(ABC) transporter
H2787_RS16495	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H2787_RS16500	COG1280	lysine exporter protein (LysE YggA)
H2787_RS16505	COG2837	iron assimilation
H2787_RS16510	COG0281	malic enzyme
H2787_RS16560	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H2787_RS16560	COG0519	Catalyzes the synthesis of GMP from XMP
H2787_RS16565	COG4399	Belongs to the UPF0754 family
H2787_RS16570	COG2259	Doxx family
H2787_RS16575	COG0586	Pfam SNARE associated Golgi protein
H2787_RS16590	COG1192	Involved in chromosome partitioning
H2787_RS16600	COG0271	Belongs to the BolA IbaG family
H2787_RS16645	COG3756	Protein conserved in bacteria
H2787_RS16670	COG1283	sodium-dependent phosphate transmembrane transporter activity
H2787_RS16675	COG0842	Transport permease protein
H2787_RS16680	COG0842	Transport permease protein
H2787_RS16680	COG1129	ABC transporter
H2787_RS16685	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H2787_RS16700	COG2326	polyphosphate kinase activity
H2787_RS16770	COG3550	peptidyl-serine autophosphorylation
H2787_RS16775	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
H2787_RS16785	COG4372	Transposase
H2787_RS16795	COG2963	transposase activity
H2787_RS16805	COG3293	Transposase
H2787_RS16830	COG1113	amino acid transport
H2787_RS16835	COG1113	amino acid transport
H2787_RS16840	COG0251	oxidation-reduction process
H2787_RS16880	COG0564	pseudouridine synthase activity
H2787_RS16940	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H2787_RS16955	COG1802	Transcriptional regulator
H2787_RS16965	COG1448	Aminotransferase
H2787_RS16970	COG0277	FAD linked oxidase domain protein
H2787_RS16980	COG2186	Transcriptional regulator
H2787_RS16995	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H2787_RS17000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H2787_RS17015	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H2787_RS17020	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H2787_RS17030	COG1215	transferase activity, transferring glycosyl groups
H2787_RS17065	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
H2787_RS17090	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H2787_RS17095	COG1596	polysaccharide export
H2787_RS17120	COG0728	peptidoglycan biosynthetic process
H2787_RS17125	COG3023	N-Acetylmuramoyl-L-alanine amidase
H2787_RS17150	COG3293	Transposase
H2787_RS17190	COG0546	phosphoglycolate phosphatase activity
H2787_RS17195	COG1028	Short-chain dehydrogenase reductase Sdr
H2787_RS17215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2787_RS17220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H2787_RS17225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H2787_RS17230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H2787_RS17235	COG1116	anion transmembrane transporter activity
H2787_RS17240	COG1309	transcriptional regulator
H2787_RS17245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H2787_RS17255	COG0196	riboflavin kinase activity
H2787_RS17260	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H2787_RS17270	COG1047	Peptidyl-prolyl cis-trans
H2787_RS17325	COG2433	Pfam Transposase IS66
H2787_RS17345	COG0657	acetylesterase activity
H2787_RS17370	COG0583	DNA-binding transcription factor activity
H2787_RS17400	COG2951	lytic endotransglycosylase activity
H2787_RS17405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H2787_RS17420	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H2787_RS17425	COG3293	Transposase
H2787_RS17435	COG0671	phosphoesterase, PA-phosphatase related
H2787_RS17440	COG0861	Integral membrane protein TerC family
H2787_RS17450	COG0754	glutathionylspermidine amidase activity
H2787_RS17460	COG0402	S-adenosylhomocysteine deaminase activity
H2787_RS17475	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H2787_RS17505	COG0706	membrane insertase activity
H2787_RS17530	COG0347	Belongs to the P(II) protein family
H2787_RS17545	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H2787_RS17565	COG2197	response regulator
H2787_RS17570	COG3850	Histidine kinase
H2787_RS17575	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H2787_RS17585	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H2787_RS17585	COG0519	Catalyzes the synthesis of GMP from XMP
H2787_RS17600	COG1064	alcohol dehydrogenase
H2787_RS17620	COG0671	phosphoesterase, PA-phosphatase related
H2787_RS17635	COG3038	cytochrome b561
H2787_RS17645	COG1192	Involved in chromosome partitioning
H2787_RS17650	COG1475	DNA binding
H2787_RS17660	COG1192	Involved in chromosome partitioning
H2787_RS17705	COG4372	Transposase
H2787_RS17715	COG2963	transposase activity
H2787_RS17795	COG0589	response to stress
H2787_RS17805	COG0586	Pfam SNARE associated Golgi protein
H2787_RS17820	COG3077	Addiction module antitoxin, RelB DinJ family
H2787_RS17825	COG2801	Transposase and inactivated derivatives
H2787_RS17870	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
H2787_RS17930	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H2787_RS17985	COG1373	ATPase (AAA superfamily
H2787_RS18030	COG0582	viral genome integration into host DNA
H2787_RS18060	COG0069	glutamate synthase activity
H2787_RS18065	COG2218	PFAM glutamate synthase alpha subunit domain protein
H2787_RS18070	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
H2787_RS18090	COG0004	ammonium transporteR
H2787_RS18100	COG0446	pyridine nucleotide-disulphide oxidoreductase
H2787_RS18100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
H2787_RS18115	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
H2787_RS18155	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
H2787_RS18165	COG1301	dicarboxylic acid transport
H2787_RS18320	COG3188	usher protein
H2787_RS18350	COG1522	sequence-specific DNA binding
H2787_RS18360	COG1126	abc transporter atp-binding protein
H2787_RS18365	COG0765	amino acid transport
H2787_RS18370	COG0765	amino acid transport
H2787_RS18385	COG2826	transposase and inactivated derivatives, IS30 family
H2787_RS18395	COG3293	Transposase
H2787_RS18420	COG2433	Pfam Transposase IS66
H2787_RS18450	COG0659	secondary active sulfate transmembrane transporter activity