locus-tag	class	description
M1L34_RS00005	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
M1L34_RS00010	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
M1L34_RS00015	COG0596	Alpha beta hydrolase
M1L34_RS00040	COG0488	(ABC) transporter
M1L34_RS00045	COG0586	Pfam SNARE associated Golgi protein
M1L34_RS00055	COG0187	DNA topoisomerase II activity
M1L34_RS00065	COG0592	DNA-directed DNA polymerase activity
M1L34_RS00090	COG0706	membrane insertase activity
M1L34_RS00105	COG1230	cation diffusion facilitator family transporter
M1L34_RS00110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1L34_RS00125	COG0402	S-adenosylhomocysteine deaminase activity
M1L34_RS00135	COG0754	glutathionylspermidine amidase activity
M1L34_RS00145	COG0861	Integral membrane protein TerC family
M1L34_RS00150	COG0671	phosphoesterase, PA-phosphatase related
M1L34_RS00160	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
M1L34_RS00175	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
M1L34_RS00180	COG2951	lytic endotransglycosylase activity
M1L34_RS00210	COG0583	DNA-binding transcription factor activity
M1L34_RS00230	COG0657	acetylesterase activity
M1L34_RS00235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
M1L34_RS00275	COG1047	Peptidyl-prolyl cis-trans
M1L34_RS00285	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
M1L34_RS00290	COG0196	riboflavin kinase activity
M1L34_RS00300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
M1L34_RS00310	COG1116	anion transmembrane transporter activity
M1L34_RS00315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1L34_RS00320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1L34_RS00325	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1L34_RS00330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1L34_RS00350	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS00355	COG0546	phosphoglycolate phosphatase activity
M1L34_RS00410	COG3023	N-Acetylmuramoyl-L-alanine amidase
M1L34_RS00415	COG0728	peptidoglycan biosynthetic process
M1L34_RS00445	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
M1L34_RS00450	COG1086	Polysaccharide biosynthesis protein
M1L34_RS00455	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
M1L34_RS00460	COG1083	cytidylyl-transferase
M1L34_RS00475	COG2089	acid synthase
M1L34_RS00480	COG2244	polysaccharide biosynthetic process
M1L34_RS00500	COG1216	Glycosyl transferase, family 2
M1L34_RS00505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
M1L34_RS00510	COG1210	Utp--glucose-1-phosphate uridylyltransferase
M1L34_RS00525	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1L34_RS00530	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1L34_RS00540	COG2186	Transcriptional regulator
M1L34_RS00550	COG0277	FAD linked oxidase domain protein
M1L34_RS00555	COG1448	Aminotransferase
M1L34_RS00565	COG1802	Transcriptional regulator
M1L34_RS00580	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
M1L34_RS00600	COG1051	belongs to the nudix hydrolase family
M1L34_RS00635	COG0564	pseudouridine synthase activity
M1L34_RS00675	COG0251	oxidation-reduction process
M1L34_RS00680	COG1113	amino acid transport
M1L34_RS00685	COG1113	amino acid transport
M1L34_RS00705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1L34_RS00710	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS00715	COG1024	Enoyl-CoA hydratase
M1L34_RS00720	COG1024	Enoyl-CoA hydratase
M1L34_RS00725	COG0477	Major facilitator Superfamily
M1L34_RS00730	COG3916	Acyl-homoserine-lactone synthase
M1L34_RS00740	COG2197	response regulator
M1L34_RS00750	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS00755	COG3321	synthase
M1L34_RS00755	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
M1L34_RS00755	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1L34_RS00755	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
M1L34_RS00775	COG2267	carboxylic ester hydrolase activity
M1L34_RS00795	COG0271	Belongs to the BolA IbaG family
M1L34_RS00805	COG1192	Involved in chromosome partitioning
M1L34_RS00820	COG0586	Pfam SNARE associated Golgi protein
M1L34_RS00825	COG2259	Doxx family
M1L34_RS00830	COG4399	Belongs to the UPF0754 family
M1L34_RS00835	COG0519	Catalyzes the synthesis of GMP from XMP
M1L34_RS00835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1L34_RS00880	COG0281	malic enzyme
M1L34_RS00890	COG2837	iron assimilation
M1L34_RS00895	COG1280	lysine exporter protein (LysE YggA)
M1L34_RS00900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
M1L34_RS00905	COG1121	(ABC) transporter
M1L34_RS00970	COG0386	Belongs to the glutathione peroxidase family
M1L34_RS00985	COG1309	transcriptional regulator
M1L34_RS00990	COG0697	spore germination
M1L34_RS01000	COG0758	DNA mediated transformation
M1L34_RS01070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
M1L34_RS01080	COG0655	NAD(P)H dehydrogenase (quinone) activity
M1L34_RS01120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
M1L34_RS01130	COG2814	Major facilitator Superfamily
M1L34_RS01140	COG1253	flavin adenine dinucleotide binding
M1L34_RS01150	COG2860	membrane
M1L34_RS01155	COG0477	Major facilitator Superfamily
M1L34_RS01165	COG0318	PFAM AMP-dependent synthetase and ligase
M1L34_RS01180	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
M1L34_RS01200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1L34_RS01210	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1L34_RS01245	COG0589	response to stress
M1L34_RS01250	COG0659	secondary active sulfate transmembrane transporter activity
M1L34_RS01280	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1L34_RS01325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1L34_RS01355	COG0589	response to stress
M1L34_RS01360	COG0659	secondary active sulfate transmembrane transporter activity
M1L34_RS01420	COG0347	Belongs to the P(II) protein family
M1L34_RS01425	COG0004	ammonium transporteR
M1L34_RS01435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1L34_RS01435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
M1L34_RS01475	COG0795	lipopolysaccharide-transporting ATPase activity
M1L34_RS01480	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
M1L34_RS01485	COG0793	Belongs to the peptidase S41A family
M1L34_RS01500	COG2197	response regulator
M1L34_RS01510	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
M1L34_RS01520	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1L34_RS01525	COG4974	Belongs to the 'phage' integrase family
M1L34_RS01550	COG0772	Belongs to the SEDS family
M1L34_RS01555	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1L34_RS01560	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
M1L34_RS01565	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1L34_RS01590	COG0697	spore germination
M1L34_RS01595	COG1538	Outer membrane efflux protein
M1L34_RS01615	COG3275	phosphorelay sensor kinase activity
M1L34_RS01625	COG0181	hydroxymethylbilane synthase activity
M1L34_RS01670	COG1716	ATPase activity
M1L34_RS01675	COG0546	phosphoglycolate phosphatase activity
M1L34_RS01770	COG0596	Alpha beta hydrolase
M1L34_RS01775	COG2056	Na+-H+ antiporter family
M1L34_RS01790	COG0326	Molecular chaperone. Has ATPase activity
M1L34_RS01805	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
M1L34_RS01870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
M1L34_RS01875	COG2169	Transcriptional regulator
M1L34_RS01875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1L34_RS01905	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
M1L34_RS01915	COG0497	DNA recombination
M1L34_RS01930	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1L34_RS01940	COG0237	dephospho-CoA kinase activity
M1L34_RS01945	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
M1L34_RS01995	COG0195	Participates in both transcription termination and antitermination
M1L34_RS02010	COG1320	monovalent cation:proton antiporter activity
M1L34_RS02015	COG2212	antiporter activity
M1L34_RS02020	COG1863	multisubunit Na H antiporter MnhE subunit
M1L34_RS02025	COG0651	ATP synthesis coupled electron transport
M1L34_RS02030	COG1006	Multisubunit Na H antiporter MnhC subunit
M1L34_RS02035	COG2111	Na H antiporter
M1L34_RS02035	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1L34_RS02050	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
M1L34_RS02055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1L34_RS02070	COG2226	methyltransferase
M1L34_RS02090	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
M1L34_RS02095	COG1074	ATP-dependent DNA helicase activity
M1L34_RS02100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1L34_RS02105	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1L34_RS02120	COG0598	Magnesium transport protein CorA
M1L34_RS02125	COG0789	Transcriptional regulator
M1L34_RS02130	COG0484	heat shock protein binding
M1L34_RS02140	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
M1L34_RS02145	COG0475	glutathione-regulated potassium exporter activity
M1L34_RS02145	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1L34_RS02150	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
M1L34_RS02170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1L34_RS02180	COG4535	Mg2 and Co2 transporter CorC
M1L34_RS02185	COG0425	Belongs to the sulfur carrier protein TusA family
M1L34_RS02190	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
M1L34_RS02190	COG0644	oxidoreductase
M1L34_RS02200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1L34_RS02215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1L34_RS02220	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
M1L34_RS02260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
M1L34_RS02275	COG0534	Mate efflux family protein
M1L34_RS02285	COG0635	Involved in the biosynthesis of porphyrin-containing compound
M1L34_RS02290	COG4221	oxidoreductase activity
M1L34_RS02295	COG0583	DNA-binding transcription factor activity
M1L34_RS02310	COG0318	PFAM AMP-dependent synthetase and ligase
M1L34_RS02315	COG1530	ribonuclease E activity
M1L34_RS02325	COG0546	phosphoglycolate phosphatase activity
M1L34_RS02330	COG2378	regulation of single-species biofilm formation
M1L34_RS02335	COG0625	glutathione transferase activity
M1L34_RS02345	COG0583	DNA-binding transcription factor activity
M1L34_RS02410	COG0473	3-isopropylmalate dehydrogenase activity
M1L34_RS02465	COG1301	dicarboxylic acid transport
M1L34_RS02475	COG1560	Kdo2-lipid A biosynthetic process
M1L34_RS02480	COG1280	lysine exporter protein (LysE YggA)
M1L34_RS02485	COG0488	(ABC) transporter
M1L34_RS02490	COG2900	Belongs to the SlyX family
M1L34_RS02500	COG1733	regulation of RNA biosynthetic process
M1L34_RS02525	COG0210	DNA helicase
M1L34_RS02530	COG0724	RNA recognition motif
M1L34_RS02550	COG4651	solute:proton antiporter activity
M1L34_RS02550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1L34_RS02575	COG0788	formyltetrahydrofolate deformylase activity
M1L34_RS02675	COG2813	Specifically methylates the guanine in position
M1L34_RS02675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1L34_RS02685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
M1L34_RS02695	COG4774	siderophore transport
M1L34_RS02705	COG0740	serine-type endopeptidase activity
M1L34_RS02725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
M1L34_RS02725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
M1L34_RS02730	COG0280	phosphate acetyltransferase
M1L34_RS02730	COG0857	belongs to the CobB CobQ family
M1L34_RS02735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
M1L34_RS02745	COG0800	Aldolase
M1L34_RS02755	COG3265	gluconokinase activity
M1L34_RS02760	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS02770	COG2267	carboxylic ester hydrolase activity
M1L34_RS02785	COG0793	Belongs to the peptidase S41A family
M1L34_RS02820	COG1426	Protein conserved in bacteria
M1L34_RS02865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
M1L34_RS02875	COG0318	PFAM AMP-dependent synthetase and ligase
M1L34_RS02890	COG2986	histidine ammonia-lyase
M1L34_RS02930	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS02935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
M1L34_RS02955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
M1L34_RS02965	COG1162	GTPase activity
M1L34_RS02970	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
M1L34_RS02985	COG1538	Outer membrane efflux protein
M1L34_RS02990	COG0577	efflux transmembrane transporter activity
M1L34_RS02990	COG1136	(ABC) transporter
M1L34_RS02995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1L34_RS03020	COG0028	Belongs to the TPP enzyme family
M1L34_RS03025	COG0440	acetolactate synthase activity
M1L34_RS03055	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
M1L34_RS03070	COG0084	hydrolase, TatD family'
M1L34_RS03085	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
M1L34_RS03095	COG0583	DNA-binding transcription factor activity
M1L34_RS03105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1L34_RS03110	COG2814	Major facilitator Superfamily
M1L34_RS03120	COG0697	spore germination
M1L34_RS03150	COG3622	Belongs to the hyi family
M1L34_RS03155	COG2084	Dehydrogenase
M1L34_RS03160	COG1024	Enoyl-CoA hydratase
M1L34_RS03165	COG0784	Response regulator, receiver
M1L34_RS03165	COG2205	protein histidine kinase activity
M1L34_RS03165	COG5002	protein histidine kinase activity
M1L34_RS03185	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1L34_RS03195	COG3956	TIGRFAM MazG family protein
M1L34_RS03200	COG1555	photosystem II stabilization
M1L34_RS03205	COG0617	tRNA 3'-terminal CCA addition
M1L34_RS03210	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
M1L34_RS03230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1L34_RS03235	COG3028	Belongs to the UPF0307 family
M1L34_RS03240	COG0318	PFAM AMP-dependent synthetase and ligase
M1L34_RS03255	COG0625	glutathione transferase activity
M1L34_RS03260	COG1238	metal cluster binding
M1L34_RS03305	COG0072	phenylalanine-tRNA ligase activity
M1L34_RS03335	COG0248	Ppx GppA phosphatase
M1L34_RS03345	COG0037	tRNA processing
M1L34_RS03385	COG1764	response to oxidative stress
M1L34_RS03390	COG1846	Transcriptional regulator
M1L34_RS03400	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1L34_RS03460	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
M1L34_RS03465	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
M1L34_RS03470	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
M1L34_RS03480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
M1L34_RS03530	COG1214	PFAM Peptidase M22, glycoprotease
M1L34_RS03555	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
M1L34_RS03560	COG0561	phosphatase activity
M1L34_RS03570	COG2132	Multicopper oxidase
M1L34_RS03575	COG3667	copper resistance
M1L34_RS03590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
M1L34_RS03595	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
M1L34_RS03600	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
M1L34_RS03630	COG1063	alcohol dehydrogenase
M1L34_RS03635	COG0583	DNA-binding transcription factor activity
M1L34_RS03640	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS03645	COG2814	Major facilitator Superfamily
M1L34_RS03650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
M1L34_RS03660	COG1053	succinate dehydrogenase
M1L34_RS03665	COG0583	DNA-binding transcription factor activity
M1L34_RS03680	COG0583	DNA-binding transcription factor activity
M1L34_RS03710	COG0583	DNA-binding transcription factor activity
M1L34_RS03725	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1L34_RS03750	COG0384	phenazine biosynthesis protein PhzF
M1L34_RS03775	COG4993	Dehydrogenase
M1L34_RS03845	COG2205	protein histidine kinase activity
M1L34_RS03855	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
M1L34_RS03875	COG0745	RESPONSE REGULATOR receiver
M1L34_RS03915	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
M1L34_RS03945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
M1L34_RS03950	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
M1L34_RS03970	COG0583	DNA-binding transcription factor activity
M1L34_RS03990	COG0668	transmembrane transport
M1L34_RS04000	COG2081	HI0933 family
M1L34_RS04005	COG2515	1-aminocyclopropane-1-carboxylate deaminase
M1L34_RS04035	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1L34_RS04035	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
M1L34_RS04045	COG0489	protein tyrosine kinase activity
M1L34_RS04095	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
M1L34_RS04105	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
M1L34_RS04120	COG0730	response to heat
M1L34_RS04130	COG1196	nuclear chromosome segregation
M1L34_RS04150	COG2223	nitrite transmembrane transporter activity
M1L34_RS04155	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
M1L34_RS04160	COG1877	trehalose-phosphatase activity
M1L34_RS04165	COG0596	Alpha beta hydrolase
M1L34_RS04165	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1L34_RS04165	COG2226	methyltransferase
M1L34_RS04180	COG4106	trans-aconitate 2-methyltransferase activity
M1L34_RS04195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
M1L34_RS04200	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
M1L34_RS04205	COG0009	L-threonylcarbamoyladenylate synthase
M1L34_RS04210	COG3101	peptidyl-lysine hydroxylation
M1L34_RS04215	COG1399	metal-binding, possibly nucleic acid-binding protein
M1L34_RS04240	COG1652	LysM domain
M1L34_RS04245	COG0351	phosphomethylpyrimidine kinase
M1L34_RS04245	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1L34_RS04245	COG0352	thiamine-phosphate diphosphorylase activity
M1L34_RS04255	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
M1L34_RS04285	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1L34_RS04315	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
M1L34_RS04330	COG0358	DNA primase activity
M1L34_RS04340	COG0564	pseudouridine synthase activity
M1L34_RS04365	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1L34_RS04385	COG0583	DNA-binding transcription factor activity
M1L34_RS04390	COG0473	3-isopropylmalate dehydrogenase activity
M1L34_RS04400	COG0657	acetylesterase activity
M1L34_RS04410	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS04430	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
M1L34_RS04430	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
M1L34_RS04445	COG1981	membrane
M1L34_RS04490	COG0456	acetyltransferase
M1L34_RS04500	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
M1L34_RS04505	COG0492	ferredoxin-NADP+ reductase activity
M1L34_RS04510	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
M1L34_RS04510	COG1674	ftsk spoiiie
M1L34_RS04515	COG1280	lysine exporter protein (LysE YggA)
M1L34_RS04540	COG2894	cell division
M1L34_RS04555	COG0204	Acyl-transferase
M1L34_RS04560	COG2885	chlorophyll binding
M1L34_RS04565	COG0210	DNA helicase
M1L34_RS04575	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
M1L34_RS04590	COG0121	glutamine amidotransferase
M1L34_RS04610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
M1L34_RS04615	COG0735	belongs to the Fur family
M1L34_RS04640	COG0420	3'-5' exonuclease activity
M1L34_RS04660	COG1090	epimerase
M1L34_RS04675	COG2050	protein possibly involved in aromatic compounds catabolism
M1L34_RS04685	COG2814	Major facilitator Superfamily
M1L34_RS04690	COG0405	Gamma-glutamyltransferase
M1L34_RS04730	COG0477	Major facilitator Superfamily
M1L34_RS04735	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1L34_RS04760	COG0531	amino acid
M1L34_RS04765	COG2040	homocysteine
M1L34_RS04790	COG1309	transcriptional regulator
M1L34_RS04795	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1L34_RS04800	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1L34_RS04810	COG1607	acyl-coa hydrolase
M1L34_RS04820	COG0523	cobalamin synthesis protein
M1L34_RS04830	COG4681	YaeQ
M1L34_RS04840	COG1649	PFAM Uncharacterised BCR, COG1649
M1L34_RS04840	COG0726	polysaccharide deacetylase
M1L34_RS04845	COG1215	transferase activity, transferring glycosyl groups
M1L34_RS04855	COG1024	Enoyl-CoA hydratase
M1L34_RS04870	COG1414	Transcriptional regulator
M1L34_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS04900	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1L34_RS04905	COG2271	Major facilitator Superfamily
M1L34_RS04915	COG2267	carboxylic ester hydrolase activity
M1L34_RS04920	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS04935	COG0028	Belongs to the TPP enzyme family
M1L34_RS04945	COG0477	Major facilitator Superfamily
M1L34_RS04950	COG0242	peptide deformylase activity
M1L34_RS04955	COG2066	Belongs to the glutaminase family
M1L34_RS04960	COG2207	Transcriptional regulator
M1L34_RS04965	COG2223	nitrite transmembrane transporter activity
M1L34_RS04980	COG0583	DNA-binding transcription factor activity
M1L34_RS04985	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS04990	COG2271	Major facilitator Superfamily
M1L34_RS04995	COG3959	Transketolase, thiamine diphosphate binding domain
M1L34_RS05000	COG3958	Transketolase
M1L34_RS05010	COG0306	phosphate transporter
M1L34_RS05030	COG1262	PFAM Formylglycine-generating sulfatase enzyme
M1L34_RS05075	COG4181	ATPase activity
M1L34_RS05080	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
M1L34_RS05105	COG0583	DNA-binding transcription factor activity
M1L34_RS05115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1L34_RS05120	COG1773	rubredoxin
M1L34_RS05170	COG2851	Citrate transporter
M1L34_RS05175	COG1253	flavin adenine dinucleotide binding
M1L34_RS05215	COG0804	urea catabolic process
M1L34_RS05225	COG0830	nickel cation binding
M1L34_RS05240	COG0742	ribosomal rna small subunit methyltransferase
M1L34_RS05245	COG0768	penicillin binding
M1L34_RS05270	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
M1L34_RS05275	COG2878	Part of a membrane complex involved in electron transport
M1L34_RS05280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1L34_RS05290	COG3384	dioxygenase
M1L34_RS05335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
M1L34_RS05660	COG0739	heme binding
M1L34_RS05705	COG2194	sulfuric ester hydrolase activity
M1L34_RS05745	COG0006	proline dipeptidase activity
M1L34_RS05750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1L34_RS05755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1L34_RS05775	COG1279	arginine transmembrane transporter activity
M1L34_RS05780	COG0583	DNA-binding transcription factor activity
M1L34_RS05820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1L34_RS05825	COG1388	LysM domain
M1L34_RS05825	COG0741	lytic transglycosylase activity
M1L34_RS05825	COG1388	LysM domain
M1L34_RS05825	COG0741	lytic transglycosylase activity
M1L34_RS05835	COG4174	ABC transporter (Permease)
M1L34_RS05840	COG4239	(ABC) transporter, permease
M1L34_RS05845	COG4172	Belongs to the ABC transporter superfamily
M1L34_RS05865	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
M1L34_RS05875	COG5001	Diguanylate cyclase
M1L34_RS05875	COG4251	negative regulation of phosphorylation
M1L34_RS05875	COG3706	GGDEF domain
M1L34_RS05875	COG2203	Gaf domain
M1L34_RS05885	COG1902	pentaerythritol trinitrate reductase activity
M1L34_RS05885	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1L34_RS05900	COG4269	membrane
M1L34_RS05965	COG0789	Transcriptional regulator
M1L34_RS06050	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
M1L34_RS06100	COG0300	oxidoreductase activity
M1L34_RS06110	COG1309	transcriptional regulator
M1L34_RS06115	COG1741	Belongs to the pirin family
M1L34_RS06130	COG2072	flavoprotein involved in K transport
M1L34_RS06140	COG2252	PERMEase
M1L34_RS06145	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
M1L34_RS06150	COG3038	cytochrome b561
M1L34_RS06160	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
M1L34_RS06170	COG0527	aspartate kinase activity
M1L34_RS06180	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
M1L34_RS06190	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
M1L34_RS06205	COG0667	Aldo Keto reductase
M1L34_RS06220	COG1765	OsmC-like protein
M1L34_RS06235	COG0542	response to heat
M1L34_RS06270	COG2885	chlorophyll binding
M1L34_RS06280	COG0625	glutathione transferase activity
M1L34_RS06285	COG0220	tRNA (guanine-N7-)-methyltransferase activity
M1L34_RS06305	COG3634	alkyl hydroperoxide reductase activity
M1L34_RS06315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
M1L34_RS06325	COG0450	alkyl hydroperoxide reductase
M1L34_RS06330	COG1643	Atp-dependent helicase
M1L34_RS06345	COG2814	Major facilitator Superfamily
M1L34_RS06350	COG3135	benzoate transporter
M1L34_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS06360	COG0543	2 iron, 2 sulfur cluster binding
M1L34_RS06360	COG0633	Ferredoxin
M1L34_RS06365	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1L34_RS06370	COG4638	Rieske (2fe-2S)
M1L34_RS06380	COG0583	DNA-binding transcription factor activity
M1L34_RS06430	COG1570	exodeoxyribonuclease VII activity
M1L34_RS06460	COG1280	lysine exporter protein (LysE YggA)
M1L34_RS06465	COG1278	Cold shock
M1L34_RS06500	COG2814	Major facilitator Superfamily
M1L34_RS06535	COG0517	IMP dehydrogenase activity
M1L34_RS06535	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
M1L34_RS06540	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
M1L34_RS06550	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
M1L34_RS06555	COG1137	ATPase activity
M1L34_RS06560	COG1538	Outer membrane efflux protein
M1L34_RS06590	COG4122	O-methyltransferase activity
M1L34_RS06600	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
M1L34_RS06615	COG1522	sequence-specific DNA binding
M1L34_RS06620	COG5006	permease, DMT superfamily
M1L34_RS06630	COG1560	Kdo2-lipid A biosynthetic process
M1L34_RS06645	COG2814	Major facilitator Superfamily
M1L34_RS06665	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1L34_RS06715	COG0583	DNA-binding transcription factor activity
M1L34_RS06720	COG1914	H( )-stimulated, divalent metal cation uptake system
M1L34_RS06740	COG4770	biotin carboxylase activity
M1L34_RS06745	COG0038	chloride channel
M1L34_RS06765	COG1309	transcriptional regulator
M1L34_RS06775	COG1063	alcohol dehydrogenase
M1L34_RS06790	COG0439	Biotin carboxylase
M1L34_RS06815	COG0864	Transcriptional regulator
M1L34_RS06825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1L34_RS06830	COG1116	anion transmembrane transporter activity
M1L34_RS06950	COG0590	tRNA wobble adenosine to inosine editing
M1L34_RS06955	COG2807	transmembrane transport
M1L34_RS06970	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
M1L34_RS06980	COG0789	Transcriptional regulator
M1L34_RS06990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1L34_RS07010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1L34_RS07020	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1L34_RS07035	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS07040	COG0531	amino acid
M1L34_RS07045	COG1760	l-serine dehydratase
M1L34_RS07050	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS07050	COG2030	dehydratase
M1L34_RS07055	COG3396	Phenylacetate-CoA oxygenase
M1L34_RS07060	COG3460	Phenylacetate-CoA oxygenase
M1L34_RS07065	COG3396	Phenylacetate-CoA oxygenase
M1L34_RS07070	COG2151	metal-sulfur cluster biosynthetic enzyme
M1L34_RS07075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1L34_RS07080	COG1024	Enoyl-CoA hydratase
M1L34_RS07085	COG1024	Enoyl-CoA hydratase
M1L34_RS07090	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1L34_RS07095	COG0183	Belongs to the thiolase family
M1L34_RS07100	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
M1L34_RS07105	COG3327	negative regulation of DNA-templated transcription, initiation
M1L34_RS07115	COG2050	protein possibly involved in aromatic compounds catabolism
M1L34_RS07145	COG0753	catalase activity
M1L34_RS07150	COG3038	cytochrome b561
M1L34_RS07170	COG2267	carboxylic ester hydrolase activity
M1L34_RS07175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1L34_RS07180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1L34_RS07185	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS07195	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1L34_RS07205	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS07210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1L34_RS07215	COG0583	DNA-binding transcription factor activity
M1L34_RS07225	COG1414	Transcriptional regulator
M1L34_RS07230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1L34_RS07240	COG1840	ABC-type Fe3 transport system, periplasmic component
M1L34_RS07245	COG3842	ATPase activity
M1L34_RS07260	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
M1L34_RS07265	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1L34_RS07270	COG2814	Major facilitator Superfamily
M1L34_RS07275	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS07290	COG1024	Enoyl-CoA hydratase
M1L34_RS07300	COG2814	Major facilitator Superfamily
M1L34_RS07310	COG0183	Belongs to the thiolase family
M1L34_RS07315	COG1250	3-hydroxyacyl-CoA dehydrogenase
M1L34_RS07320	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS07325	COG1024	Enoyl-CoA hydratase
M1L34_RS07330	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS07335	COG2814	Major facilitator Superfamily
M1L34_RS07340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1L34_RS07345	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1L34_RS07355	COG2814	Major facilitator Superfamily
M1L34_RS07365	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS07380	COG0583	DNA-binding transcription factor activity
M1L34_RS07390	COG4770	biotin carboxylase activity
M1L34_RS07395	COG1024	Enoyl-CoA hydratase
M1L34_RS07400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1L34_RS07405	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS07410	COG1309	transcriptional regulator
M1L34_RS07415	COG0318	PFAM AMP-dependent synthetase and ligase
M1L34_RS07435	COG0583	DNA-binding transcription factor activity
M1L34_RS07485	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS07505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
M1L34_RS07525	COG0784	Response regulator, receiver
M1L34_RS07525	COG2205	protein histidine kinase activity
M1L34_RS07545	COG0765	amino acid transport
M1L34_RS07550	COG0765	amino acid transport
M1L34_RS07555	COG1126	abc transporter atp-binding protein
M1L34_RS07560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1L34_RS07565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
M1L34_RS07580	COG1280	lysine exporter protein (LysE YggA)
M1L34_RS07590	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
M1L34_RS07595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1L34_RS07600	COG1045	serine acetyltransferase
M1L34_RS07615	COG0583	DNA-binding transcription factor activity
M1L34_RS07620	COG0625	glutathione transferase activity
M1L34_RS07625	COG0625	glutathione transferase activity
M1L34_RS07630	COG0583	DNA-binding transcription factor activity
M1L34_RS07640	COG1346	cytolysis
M1L34_RS07660	COG2814	Major facilitator Superfamily
M1L34_RS07670	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
M1L34_RS07675	COG3052	prosthetic group binding
M1L34_RS07695	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
M1L34_RS07715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1L34_RS07725	COG1294	oxidase, subunit
M1L34_RS07730	COG1271	oxidase subunit
M1L34_RS07755	COG0477	Major facilitator Superfamily
M1L34_RS07765	COG4521	taurine ABC transporter
M1L34_RS07770	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
M1L34_RS07775	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1L34_RS07780	COG2175	clavaminate synthase activity
M1L34_RS07790	COG1953	Uracil, thiamine, allantoin
M1L34_RS07800	COG0583	DNA-binding transcription factor activity
M1L34_RS07810	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
M1L34_RS07825	COG0640	Transcriptional regulator
M1L34_RS07830	COG0798	PFAM Bile acid sodium symporter
M1L34_RS07835	COG0583	DNA-binding transcription factor activity
M1L34_RS07850	COG3634	alkyl hydroperoxide reductase activity
M1L34_RS07890	COG0436	Aminotransferase
M1L34_RS07900	COG0386	Belongs to the glutathione peroxidase family
M1L34_RS07940	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1L34_RS07965	COG0012	GTP binding
M1L34_RS07970	COG2011	ABC-type metal ion transport system permease component
M1L34_RS07975	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1L34_RS07985	COG1464	Belongs to the NlpA lipoprotein family
M1L34_RS08015	COG0765	amino acid transport
M1L34_RS08020	COG0765	amino acid transport
M1L34_RS08025	COG1126	abc transporter atp-binding protein
M1L34_RS08035	COG1522	sequence-specific DNA binding
M1L34_RS08050	COG1309	transcriptional regulator
M1L34_RS08070	COG0583	DNA-binding transcription factor activity
M1L34_RS08080	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
M1L34_RS08090	COG0697	spore germination
M1L34_RS08115	COG3121	Chaperone
M1L34_RS08120	COG3539	Fimbrial protein
M1L34_RS08145	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
M1L34_RS08145	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
M1L34_RS08190	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
M1L34_RS08200	COG2353	YceI-like domain
M1L34_RS08210	COG3698	Phosphodiester glycosidase
M1L34_RS08225	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
M1L34_RS08230	COG0506	proline dehydrogenase activity
M1L34_RS08230	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M1L34_RS08230	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
M1L34_RS08240	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1L34_RS08245	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
M1L34_RS08265	COG1132	(ABC) transporter
M1L34_RS08270	COG3122	Protein conserved in bacteria
M1L34_RS08275	COG3619	membrane
M1L34_RS08285	COG0640	Transcriptional regulator
M1L34_RS08295	COG2850	peptidyl-arginine hydroxylation
M1L34_RS08300	COG0424	maF-like protein
M1L34_RS08320	COG0191	fructose-bisphosphate aldolase activity
M1L34_RS08325	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1L34_RS08340	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
M1L34_RS08350	COG1192	Involved in chromosome partitioning
M1L34_RS08355	COG1475	DNA binding
M1L34_RS08360	COG0811	peptide transport
M1L34_RS08370	COG1132	(ABC) transporter
M1L34_RS08375	COG1663	tetraacyldisaccharide 4'-kinase activity
M1L34_RS08395	COG0084	hydrolase, TatD family'
M1L34_RS08460	COG0776	regulation of translation
M1L34_RS08490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
M1L34_RS08550	COG0305	Participates in initiation and elongation during chromosome replication
M1L34_RS08635	COG4695	Portal protein
M1L34_RS08695	COG0739	heme binding
M1L34_RS08695	COG1196	nuclear chromosome segregation
M1L34_RS08695	COG0741	lytic transglycosylase activity
M1L34_RS08765	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
M1L34_RS08815	COG0339	signal peptide processing
M1L34_RS08825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
M1L34_RS08860	COG0702	epimerase
M1L34_RS08865	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1L34_RS08885	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
M1L34_RS08915	COG0316	Belongs to the HesB IscA family
M1L34_RS08920	COG0822	iron-sulfur transferase activity
M1L34_RS08945	COG0776	regulation of translation
M1L34_RS08950	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
M1L34_RS08955	COG2207	Transcriptional regulator
M1L34_RS08960	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1L34_RS08965	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS08970	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS08985	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
M1L34_RS09005	COG4264	IucA IucC family
M1L34_RS09010	COG4264	IucA IucC family
M1L34_RS09050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
M1L34_RS09065	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
M1L34_RS09085	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
M1L34_RS09090	COG0730	response to heat
M1L34_RS09110	COG4773	Receptor
M1L34_RS09115	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1L34_RS09130	COG1131	(ABC) transporter
M1L34_RS09135	COG0842	Transport permease protein
M1L34_RS09140	COG0842	Transport permease protein
M1L34_RS09195	COG2226	methyltransferase
M1L34_RS09220	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
M1L34_RS09255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1L34_RS09265	COG0133	tryptophan synthase activity
M1L34_RS09280	COG3706	GGDEF domain
M1L34_RS09295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1L34_RS09300	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
M1L34_RS09305	COG0022	dehydrogenase e1 component
M1L34_RS09310	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1L34_RS09315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1L34_RS09325	COG1063	alcohol dehydrogenase
M1L34_RS09330	COG3781	membrane
M1L34_RS09340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1L34_RS09340	COG3453	Protein conserved in bacteria
M1L34_RS09355	COG0730	response to heat
M1L34_RS09370	COG2207	Transcriptional regulator
M1L34_RS09370	COG3708	Transcriptional regulator
M1L34_RS09375	COG1733	regulation of RNA biosynthetic process
M1L34_RS09380	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
M1L34_RS09390	COG2188	Transcriptional regulator
M1L34_RS09405	COG4521	taurine ABC transporter
M1L34_RS09410	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1L34_RS09430	COG0477	Major facilitator Superfamily
M1L34_RS09445	COG1027	Aspartate ammonia-lyase
M1L34_RS09460	COG0583	DNA-binding transcription factor activity
M1L34_RS09465	COG0583	DNA-binding transcription factor activity
M1L34_RS09470	COG0183	Belongs to the thiolase family
M1L34_RS09475	COG2031	fatty acid transporter
M1L34_RS09480	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1L34_RS09490	COG0583	DNA-binding transcription factor activity
M1L34_RS09500	COG2610	gluconate transmembrane transporter activity
M1L34_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS09510	COG2207	Transcriptional regulator
M1L34_RS09525	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS09550	COG0543	2 iron, 2 sulfur cluster binding
M1L34_RS09550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1L34_RS09555	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
M1L34_RS09560	COG4638	Rieske (2fe-2S)
M1L34_RS09570	COG0725	ABC transporter, periplasmic molybdate-binding protein
M1L34_RS09575	COG4149	molybdate abc transporter
M1L34_RS09580	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
M1L34_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS09590	COG3433	isochorismatase activity
M1L34_RS09590	COG1535	isochorismatase
M1L34_RS09650	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1L34_RS09665	COG0753	catalase activity
M1L34_RS09675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
M1L34_RS09720	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1L34_RS09740	COG2072	flavoprotein involved in K transport
M1L34_RS09750	COG1538	Outer membrane efflux protein
M1L34_RS09755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
M1L34_RS09760	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1L34_RS09765	COG0745	RESPONSE REGULATOR receiver
M1L34_RS09770	COG2205	protein histidine kinase activity
M1L34_RS09780	COG2207	Transcriptional regulator
M1L34_RS09795	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS09845	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
M1L34_RS09965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
M1L34_RS09985	COG1120	ATPase activity
M1L34_RS09990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1L34_RS10000	COG1064	alcohol dehydrogenase
M1L34_RS10015	COG2207	Transcriptional regulator
M1L34_RS10020	COG2084	Dehydrogenase
M1L34_RS10030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
M1L34_RS10035	COG0583	DNA-binding transcription factor activity
M1L34_RS10045	COG0129	dihydroxy-acid dehydratase activity
M1L34_RS10050	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS10065	COG1566	PFAM secretion protein HlyD family protein
M1L34_RS10095	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
M1L34_RS10125	COG0583	DNA-binding transcription factor activity
M1L34_RS10140	COG2188	Transcriptional regulator
M1L34_RS10170	COG3210	domain, Protein
M1L34_RS10175	COG2831	hemolysin activation secretion protein
M1L34_RS10185	COG1473	amidohydrolase
M1L34_RS10195	COG0475	glutathione-regulated potassium exporter activity
M1L34_RS10195	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
M1L34_RS10205	COG0583	DNA-binding transcription factor activity
M1L34_RS10210	COG1335	isochorismatase
M1L34_RS10220	COG1309	transcriptional regulator
M1L34_RS10250	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
M1L34_RS10260	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1L34_RS10260	COG1902	pentaerythritol trinitrate reductase activity
M1L34_RS10265	COG1846	Transcriptional regulator
M1L34_RS10285	COG0753	catalase activity
M1L34_RS10300	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS10315	COG3162	membrane
M1L34_RS10325	COG3829	transcription factor binding
M1L34_RS10330	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS10335	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS10375	COG2186	Transcriptional regulator
M1L34_RS10385	COG0583	DNA-binding transcription factor activity
M1L34_RS10390	COG4948	Mandelate Racemase Muconate Lactonizing
M1L34_RS10395	COG4829	muconolactone delta-isomerase
M1L34_RS10405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1L34_RS10410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1L34_RS10415	COG0183	Belongs to the thiolase family
M1L34_RS10420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
M1L34_RS10430	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS10440	COG3733	amine oxidase
M1L34_RS10450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1L34_RS10460	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS10470	COG4638	Rieske (2fe-2S)
M1L34_RS10490	COG0154	amidase activity
M1L34_RS10500	COG2814	Major facilitator Superfamily
M1L34_RS10525	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS10530	COG0583	DNA-binding transcription factor activity
M1L34_RS10535	COG1414	Transcriptional regulator
M1L34_RS10550	COG2391	methyltransferase activity
M1L34_RS10560	COG4993	Dehydrogenase
M1L34_RS10565	COG3659	wide pore channel activity
M1L34_RS10570	COG3420	alginic acid biosynthetic process
M1L34_RS10575	COG0710	3-dehydroquinate dehydratase activity
M1L34_RS10580	COG3485	protocatechuate 3,4-dioxygenase
M1L34_RS10585	COG3485	protocatechuate 3,4-dioxygenase
M1L34_RS10590	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
M1L34_RS10595	COG2271	Major facilitator Superfamily
M1L34_RS10600	COG0596	Alpha beta hydrolase
M1L34_RS10605	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
M1L34_RS10610	COG0183	Belongs to the thiolase family
M1L34_RS10615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
M1L34_RS10620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
M1L34_RS10630	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
M1L34_RS10635	COG2323	membrane
M1L34_RS10680	COG0446	pyridine nucleotide-disulphide oxidoreductase
M1L34_RS10680	COG1902	pentaerythritol trinitrate reductase activity
M1L34_RS10705	COG0542	response to heat
M1L34_RS10710	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
M1L34_RS10740	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1L34_RS10745	COG0569	domain protein
M1L34_RS10750	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
M1L34_RS10765	COG4774	siderophore transport
M1L34_RS10770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
M1L34_RS10780	COG1585	Membrane protein implicated in regulation of membrane protease activity
M1L34_RS10795	COG1294	oxidase, subunit
M1L34_RS10800	COG4890	Cyd operon protein YbgT
M1L34_RS10815	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
M1L34_RS10825	COG0552	protein localization to endoplasmic reticulum
M1L34_RS10850	COG0516	GMP reductase activity
M1L34_RS10850	COG0517	IMP dehydrogenase activity
M1L34_RS10855	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1L34_RS10860	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
M1L34_RS10870	COG0583	DNA-binding transcription factor activity
M1L34_RS10875	COG0024	Methionine aminopeptidase
M1L34_RS10905	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
M1L34_RS10905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
M1L34_RS10910	COG1105	Belongs to the carbohydrate kinase PfkB family
M1L34_RS10915	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
M1L34_RS10915	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1L34_RS10915	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
M1L34_RS10935	COG3300	MHYT domain
M1L34_RS10935	COG5001	Diguanylate cyclase
M1L34_RS10950	COG2135	peptidase activity
M1L34_RS10955	COG0659	secondary active sulfate transmembrane transporter activity
M1L34_RS10975	COG1113	amino acid transport
M1L34_RS10985	COG1522	sequence-specific DNA binding
M1L34_RS11010	COG1011	Hydrolase
M1L34_RS11015	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
M1L34_RS11025	COG2137	regulation of response to DNA damage stimulus
M1L34_RS11040	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1L34_RS11075	COG0575	Belongs to the CDS family
M1L34_RS11080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
M1L34_RS11100	COG3852	Histidine kinase
M1L34_RS11105	COG2204	response regulator
M1L34_RS11160	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
M1L34_RS11165	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
M1L34_RS11185	COG0697	spore germination
M1L34_RS11190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1L34_RS11200	COG0303	'Molybdopterin
M1L34_RS11205	COG0521	Mo-molybdopterin cofactor biosynthetic process
M1L34_RS11205	COG0315	cyclic pyranopterin monophosphate synthase activity
M1L34_RS11220	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
M1L34_RS11225	COG0243	molybdopterin cofactor binding
M1L34_RS11235	COG0243	molybdopterin cofactor binding
M1L34_RS11240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1L34_RS11245	COG2146	nitrite reductase [NAD(P)H] activity
M1L34_RS11245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1L34_RS11255	COG0745	RESPONSE REGULATOR receiver
M1L34_RS11260	COG1116	anion transmembrane transporter activity
M1L34_RS11260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1L34_RS11280	COG0511	ligase activity, forming carbon-carbon bonds
M1L34_RS11295	COG2814	Major facilitator Superfamily
M1L34_RS11300	COG2194	sulfuric ester hydrolase activity
M1L34_RS11390	COG1598	PFAM Uncharacterised protein family UPF0150
M1L34_RS11495	COG5410	chromosome segregation
M1L34_RS11670	COG0069	glutamate synthase activity
M1L34_RS11690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
M1L34_RS11700	COG1454	alcohol dehydrogenase
M1L34_RS11705	COG0824	Thioesterase
M1L34_RS11715	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
M1L34_RS11730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
M1L34_RS11735	COG2030	dehydratase
M1L34_RS11745	COG0183	Belongs to the thiolase family
M1L34_RS11755	COG0583	DNA-binding transcription factor activity
M1L34_RS11760	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
M1L34_RS11770	COG1522	sequence-specific DNA binding
M1L34_RS11775	COG3135	benzoate transporter
M1L34_RS11785	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
M1L34_RS11810	COG0589	response to stress
M1L34_RS11815	COG0488	(ABC) transporter
M1L34_RS11835	COG4773	Receptor
M1L34_RS11865	COG0668	transmembrane transport
M1L34_RS11875	COG1309	transcriptional regulator
M1L34_RS11895	COG1605	Chorismate mutase
M1L34_RS11905	COG4221	oxidoreductase activity
M1L34_RS11915	COG0308	aminopeptidase N
M1L34_RS11935	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
M1L34_RS11945	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
M1L34_RS11950	COG1454	alcohol dehydrogenase
M1L34_RS11970	COG0531	amino acid
M1L34_RS11975	COG4303	Ethanolamine ammonia lyase large subunit
M1L34_RS11980	COG4302	ethanolamine ammonia-lyase activity
M1L34_RS11985	COG0519	Catalyzes the synthesis of GMP from XMP
M1L34_RS11985	COG0518	GMP synthase (glutamine-hydrolyzing) activity
M1L34_RS11990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
M1L34_RS12000	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
M1L34_RS12015	COG0697	spore germination
M1L34_RS12020	COG1923	regulation of RNA biosynthetic process
M1L34_RS12030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
M1L34_RS12035	COG0802	atpase or kinase
M1L34_RS12055	COG1187	pseudouridine synthase activity
M1L34_RS12070	COG0583	DNA-binding transcription factor activity
M1L34_RS12085	COG2814	Major facilitator Superfamily
M1L34_RS12090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
M1L34_RS12115	COG0729	surface antigen
M1L34_RS12135	COG0174	glutamine synthetase
M1L34_RS12140	COG0745	RESPONSE REGULATOR receiver
M1L34_RS12145	COG2205	protein histidine kinase activity
M1L34_RS12155	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
M1L34_RS12160	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
M1L34_RS12185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1L34_RS12190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1L34_RS12195	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS12210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
M1L34_RS12215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
M1L34_RS12235	COG0583	DNA-binding transcription factor activity
M1L34_RS12250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
M1L34_RS12260	COG3658	cytochrome
M1L34_RS12265	COG1215	transferase activity, transferring glycosyl groups
M1L34_RS12270	COG1649	PFAM Uncharacterised BCR, COG1649
M1L34_RS12270	COG0726	polysaccharide deacetylase
M1L34_RS12295	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
M1L34_RS12300	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
M1L34_RS12310	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
M1L34_RS12335	COG0305	Participates in initiation and elongation during chromosome replication
M1L34_RS12340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
M1L34_RS12350	COG1305	Transglutaminase-like
M1L34_RS12360	COG2308	Evidence 4 Homologs of previously reported genes of
M1L34_RS12390	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
M1L34_RS12395	COG0138	bifunctional purine biosynthesis protein purh
M1L34_RS12400	COG0151	Belongs to the GarS family
M1L34_RS12405	COG1464	Belongs to the NlpA lipoprotein family
M1L34_RS12410	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
M1L34_RS12415	COG2011	ABC-type metal ion transport system permease component
M1L34_RS12420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1L34_RS12430	COG1301	dicarboxylic acid transport
M1L34_RS12460	COG1794	racemase activity, acting on amino acids and derivatives
M1L34_RS12470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
M1L34_RS12470	COG3008	intermembrane lipid transfer
M1L34_RS12475	COG2995	paraquat-inducible protein a
M1L34_RS12485	COG2985	domain, Protein
M1L34_RS12515	COG0477	Major facilitator Superfamily
M1L34_RS12565	COG2186	Transcriptional regulator
M1L34_RS12575	COG0786	glutamate:sodium symporter activity
M1L34_RS12580	COG3243	poly(R)-hydroxyalkanoic acid synthase
M1L34_RS12605	COG3111	PFAM Bacterial OB fold (BOF) protein
M1L34_RS12705	COG1610	YqeY-like protein
M1L34_RS12710	COG4783	chaperone-mediated protein folding
M1L34_RS12735	COG1286	toxin biosynthetic process
M1L34_RS12765	COG0778	Nitroreductase
M1L34_RS12775	COG0513	Belongs to the DEAD box helicase family
M1L34_RS12800	COG2363	Small membrane protein
M1L34_RS12830	COG1234	tRNA 3'-trailer cleavage
M1L34_RS12835	COG2195	Cleaves the N-terminal amino acid of tripeptides
M1L34_RS12845	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
M1L34_RS12855	COG2819	hydrolase of the alpha beta superfamily
M1L34_RS12860	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS12865	COG1301	dicarboxylic acid transport
M1L34_RS12870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
M1L34_RS12875	COG3139	Protein of unknown function (DUF1315)
M1L34_RS12880	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
M1L34_RS12885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
M1L34_RS12895	COG0494	nUDIX hydrolase
M1L34_RS12905	COG0642	Histidine kinase
M1L34_RS12920	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
M1L34_RS12930	COG1720	tRNA m6t6A37 methyltransferase activity
M1L34_RS12945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1L34_RS12950	COG0826	peptidase U32
M1L34_RS12955	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
M1L34_RS12965	COG4598	ABC transporter
M1L34_RS12970	COG4160	amino acid transport
M1L34_RS12975	COG4215	(ABC) transporter
M1L34_RS12990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1L34_RS13035	COG1131	(ABC) transporter
M1L34_RS13040	COG0842	Transport permease protein
M1L34_RS13055	COG0772	Belongs to the SEDS family
M1L34_RS13060	COG2951	lytic endotransglycosylase activity
M1L34_RS13085	COG2207	Transcriptional regulator
M1L34_RS13100	COG0052	Belongs to the universal ribosomal protein uS2 family
M1L34_RS13105	COG0024	Methionine aminopeptidase
M1L34_RS13115	COG2223	nitrite transmembrane transporter activity
M1L34_RS13125	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1L34_RS13130	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
M1L34_RS13135	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS13150	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
M1L34_RS13155	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
M1L34_RS13160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1L34_RS13180	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1L34_RS13185	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
M1L34_RS13190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
M1L34_RS13225	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
M1L34_RS13235	COG0174	glutamine synthetase
M1L34_RS13250	COG0512	Glutamine amidotransferase of anthranilate synthase
M1L34_RS13255	COG0308	aminopeptidase N
M1L34_RS13285	COG1529	Aldehyde oxidase and xanthine dehydrogenase
M1L34_RS13295	COG0302	gtp cyclohydrolase
M1L34_RS13320	COG3739	integral membrane protein
M1L34_RS13335	COG1169	isochorismate synthase
M1L34_RS13345	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
M1L34_RS13350	COG1132	(ABC) transporter
M1L34_RS13355	COG1132	(ABC) transporter
M1L34_RS13370	COG1535	isochorismatase
M1L34_RS13370	COG3433	isochorismatase activity
M1L34_RS13375	COG1021	2,3-dihydroxybenzoate-AMP ligase
M1L34_RS13380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1L34_RS13390	COG4774	siderophore transport
M1L34_RS13395	COG4607	ABC-type enterochelin transport system periplasmic component
M1L34_RS13400	COG4604	ABC transporter, ATP-binding protein
M1L34_RS13405	COG4605	iron ion homeostasis
M1L34_RS13410	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
M1L34_RS13415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1L34_RS13430	COG2964	Protein conserved in bacteria
M1L34_RS13440	COG1741	Belongs to the pirin family
M1L34_RS13460	COG1309	transcriptional regulator
M1L34_RS13470	COG4948	Mandelate Racemase Muconate Lactonizing
M1L34_RS13475	COG2814	Major facilitator Superfamily
M1L34_RS13510	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
M1L34_RS13510	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
M1L34_RS13515	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1L34_RS13525	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS13535	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1L34_RS13540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1L34_RS13545	COG0583	DNA-binding transcription factor activity
M1L34_RS13550	COG1113	amino acid transport
M1L34_RS13570	COG2508	Transcriptional regulator
M1L34_RS13570	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
M1L34_RS13605	COG2879	small protein
M1L34_RS13610	COG1966	Carbon starvation protein
M1L34_RS13655	COG1067	ATP-dependent peptidase activity
M1L34_RS13660	COG0583	DNA-binding transcription factor activity
M1L34_RS13685	COG1686	Belongs to the peptidase S11 family
M1L34_RS13690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
M1L34_RS13725	COG0616	signal peptide processing
M1L34_RS13730	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
M1L34_RS13740	COG0573	inorganic phosphate transmembrane transporter activity
M1L34_RS13745	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
M1L34_RS13750	COG1113	amino acid transport
M1L34_RS13755	COG3961	Belongs to the TPP enzyme family
M1L34_RS13760	COG1522	sequence-specific DNA binding
M1L34_RS13770	COG0076	glutamate decarboxylase activity
M1L34_RS13775	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1L34_RS13785	COG1309	transcriptional regulator
M1L34_RS13800	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1L34_RS13835	COG0352	thiamine-phosphate diphosphorylase activity
M1L34_RS13860	COG0612	Peptidase, M16
M1L34_RS13870	COG1823	symporter activity
M1L34_RS13875	COG0583	DNA-binding transcription factor activity
M1L34_RS13880	COG0477	Major facilitator Superfamily
M1L34_RS13905	COG1187	pseudouridine synthase activity
M1L34_RS13920	COG1686	Belongs to the peptidase S11 family
M1L34_RS13925	COG1252	NADH dehydrogenase
M1L34_RS13935	COG0415	Belongs to the DNA photolyase family
M1L34_RS13950	COG1215	transferase activity, transferring glycosyl groups
M1L34_RS13980	COG2070	2-Nitropropane dioxygenase
M1L34_RS14035	COG0556	nucleotide-excision repair
M1L34_RS14055	COG0436	Aminotransferase
M1L34_RS14085	COG4221	oxidoreductase activity
M1L34_RS14095	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
M1L34_RS14100	COG1381	Involved in DNA repair and RecF pathway recombination
M1L34_RS14110	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
M1L34_RS14125	COG0681	Belongs to the peptidase S26 family
M1L34_RS14140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
M1L34_RS14160	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
M1L34_RS14165	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
M1L34_RS14170	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
M1L34_RS14180	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
M1L34_RS14185	COG4208	sulfate ABC transporter
M1L34_RS14190	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
M1L34_RS14195	COG0583	DNA-binding transcription factor activity
M1L34_RS14200	COG4625	pathogenesis
M1L34_RS14215	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
M1L34_RS14230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
M1L34_RS14240	COG1056	cytidyltransferase-related domain
M1L34_RS14240	COG1051	belongs to the nudix hydrolase family
M1L34_RS14245	COG1024	Enoyl-CoA hydratase
M1L34_RS14255	COG2814	Major facilitator Superfamily
M1L34_RS14260	COG0047	phosphoribosylformylglycinamidine synthase activity
M1L34_RS14260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
M1L34_RS14280	COG1473	amidohydrolase
M1L34_RS14285	COG0824	Thioesterase
M1L34_RS14305	COG0823	Involved in the tonB-independent uptake of proteins
M1L34_RS14325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
M1L34_RS14365	COG0628	permease
M1L34_RS14375	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
M1L34_RS14380	COG0596	Alpha beta hydrolase
M1L34_RS14385	COG0616	signal peptide processing
M1L34_RS14385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
M1L34_RS14395	COG0658	competence protein
M1L34_RS14395	COG2333	competence protein COMEC
M1L34_RS14400	COG1136	(ABC) transporter
M1L34_RS14405	COG4591	ABC-type transport system involved in lipoprotein release permease component
M1L34_RS14435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1L34_RS14455	COG0463	Glycosyl transferase, family 2
M1L34_RS14485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
M1L34_RS14490	COG1280	lysine exporter protein (LysE YggA)
M1L34_RS14500	COG0019	diaminopimelate decarboxylase activity
M1L34_RS14510	COG1113	amino acid transport
M1L34_RS14525	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
M1L34_RS14535	COG3339	Conserved Protein
M1L34_RS14540	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
M1L34_RS14545	COG0243	molybdopterin cofactor binding
M1L34_RS14550	COG1929	Belongs to the glycerate kinase type-1 family
M1L34_RS14565	COG0778	Nitroreductase
M1L34_RS14600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1L34_RS14615	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
M1L34_RS14635	COG0741	lytic transglycosylase activity
M1L34_RS14655	COG0584	glycerophosphoryl diester phosphodiesterase
M1L34_RS14660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
M1L34_RS14685	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
M1L34_RS14690	COG1597	lipid kinase activity
M1L34_RS14705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
M1L34_RS14710	COG0477	Major facilitator Superfamily
M1L34_RS14760	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
M1L34_RS14765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
M1L34_RS14790	COG0505	Belongs to the CarA family
M1L34_RS14810	COG0589	response to stress
M1L34_RS14825	COG2843	Capsule synthesis protein
M1L34_RS14925	COG2321	neutral zinc metallopeptidase
M1L34_RS14930	COG2354	Protein conserved in bacteria
M1L34_RS14950	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
M1L34_RS14975	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
M1L34_RS14980	COG1053	succinate dehydrogenase
M1L34_RS14985	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
M1L34_RS14990	COG2009	succinate dehydrogenase
M1L34_RS15030	COG2921	Belongs to the UPF0250 family
M1L34_RS15035	COG0321	lipoyl(octanoyl) transferase activity
M1L34_RS15050	COG0531	amino acid
M1L34_RS15060	COG1733	regulation of RNA biosynthetic process
M1L34_RS15065	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
M1L34_RS15070	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
M1L34_RS15070	COG1648	precorrin-2 dehydrogenase activity
M1L34_RS15085	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
M1L34_RS15115	COG0671	phosphoesterase, PA-phosphatase related
M1L34_RS15120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1L34_RS15130	COG1538	Outer membrane efflux protein
M1L34_RS15135	COG0393	Putative heavy-metal-binding
M1L34_RS15140	COG0393	Putative heavy-metal-binding
M1L34_RS15150	COG1028	Short-chain dehydrogenase reductase Sdr
M1L34_RS15160	COG0525	valine-tRNA ligase activity
M1L34_RS15180	COG0583	DNA-binding transcription factor activity
M1L34_RS15185	COG0004	ammonium transporteR
M1L34_RS15195	COG0642	Histidine kinase
M1L34_RS15200	COG0745	RESPONSE REGULATOR receiver
M1L34_RS15205	COG2194	sulfuric ester hydrolase activity
M1L34_RS15225	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1L34_RS15240	COG2315	Protein conserved in bacteria
M1L34_RS15245	COG0142	geranyltranstransferase activity
M1L34_RS15250	COG2828	Protein conserved in bacteria
M1L34_RS15255	COG1113	amino acid transport
M1L34_RS15275	COG2207	Transcriptional regulator
M1L34_RS15300	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1L34_RS15310	COG0560	Phosphoserine phosphatase
M1L34_RS15320	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
M1L34_RS15330	COG1530	ribonuclease E activity
M1L34_RS15335	COG0424	maF-like protein
M1L34_RS15340	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
M1L34_RS15345	COG1792	Involved in formation and maintenance of cell shape
M1L34_RS15350	COG1077	Cell shape determining protein MreB Mrl
M1L34_RS15355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1L34_RS15365	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
M1L34_RS15395	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
M1L34_RS15400	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
M1L34_RS15405	COG1752	Esterase of the alpha-beta hydrolase superfamily
M1L34_RS15410	COG1115	amino acid carrier protein
M1L34_RS15430	COG2814	Major facilitator Superfamily
M1L34_RS15435	COG1289	transmembrane transporter activity
M1L34_RS15445	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
M1L34_RS15485	COG1376	ErfK ybiS ycfS ynhG family protein
M1L34_RS15490	COG2832	Protein of unknown function (DUF454)
M1L34_RS15500	COG5510	response to toxic substance
M1L34_RS15520	COG0840	transmembrane signaling receptor activity
M1L34_RS15560	COG3422	double-strand break repair
M1L34_RS15565	COG2824	Alkylphosphonate utilization operon protein PhnA
M1L34_RS15570	COG3189	MarR family transcriptional regulator
M1L34_RS15580	COG0354	folic acid binding
M1L34_RS15585	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
M1L34_RS15595	COG0679	Auxin Efflux Carrier
M1L34_RS15600	COG1902	pentaerythritol trinitrate reductase activity
M1L34_RS15605	COG4772	TonB-dependent receptor
M1L34_RS15610	COG2094	Belongs to the DNA glycosylase MPG family
M1L34_RS15635	COG1217	gtp-binding protein TYPA
M1L34_RS15640	COG2233	PERMEase
M1L34_RS15650	COG0833	amino acid
M1L34_RS15655	COG1690	Belongs to the RtcB family
M1L34_RS15665	COG2885	chlorophyll binding
M1L34_RS15665	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
M1L34_RS15675	COG0183	Belongs to the thiolase family
M1L34_RS15695	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
M1L34_RS15715	COG2207	Transcriptional regulator
M1L34_RS15720	COG0183	Belongs to the thiolase family
M1L34_RS15750	COG1272	protein, Hemolysin III
M1L34_RS15755	COG0477	Major facilitator Superfamily
M1L34_RS15770	COG0450	alkyl hydroperoxide reductase
M1L34_RS15790	COG0285	dihydrofolate synthase activity
M1L34_RS15840	COG2096	Adenosyltransferase
M1L34_RS15860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
M1L34_RS15865	COG0745	RESPONSE REGULATOR receiver
M1L34_RS15870	COG2205	protein histidine kinase activity
M1L34_RS15880	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS15885	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS15890	COG0583	DNA-binding transcription factor activity
M1L34_RS15895	COG0625	glutathione transferase activity
M1L34_RS15960	COG0438	transferase activity, transferring glycosyl groups
M1L34_RS15965	COG0463	Glycosyl transferase, family 2
M1L34_RS15970	COG0726	polysaccharide deacetylase
M1L34_RS15990	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
M1L34_RS15995	COG2205	protein histidine kinase activity
M1L34_RS16045	COG1862	Preprotein translocase
M1L34_RS16055	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
M1L34_RS16060	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
M1L34_RS16070	COG3781	membrane
M1L34_RS16075	COG0613	PHP domain protein
M1L34_RS16085	COG2350	Protein conserved in bacteria
M1L34_RS16115	COG1607	acyl-coa hydrolase
M1L34_RS16175	COG2199	diguanylate cyclase activity
M1L34_RS16185	COG1408	metallophosphoesterase
M1L34_RS16190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
M1L34_RS16200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
M1L34_RS16220	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
M1L34_RS16225	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
M1L34_RS16240	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
M1L34_RS16250	COG2969	positive regulation of protein catabolic process
M1L34_RS16270	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS16275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
M1L34_RS16290	COG1309	transcriptional regulator
M1L34_RS16295	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS16340	COG1183	phosphatidylcholine synthase activity
M1L34_RS16345	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
M1L34_RS16375	COG1196	nuclear chromosome segregation
M1L34_RS16375	COG0739	heme binding
M1L34_RS16375	COG0741	lytic transglycosylase activity
M1L34_RS16385	COG1702	phosphate starvation-inducible protein PhoH
M1L34_RS16420	COG1295	ribonuclease BN
M1L34_RS16425	COG0697	spore germination
M1L34_RS16430	COG2169	Transcriptional regulator
M1L34_RS16435	COG0179	Fumarylacetoacetate (FAA) hydrolase
M1L34_RS16480	COG0557	exoribonuclease II activity
M1L34_RS16485	COG0339	signal peptide processing
M1L34_RS16490	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
M1L34_RS16520	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
M1L34_RS16525	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS16680	COG0626	cystathionine gamma-synthase activity
M1L34_RS16685	COG0433	COG0433 Predicted ATPase
M1L34_RS16690	COG1017	nitric oxide dioxygenase activity
M1L34_RS16690	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
M1L34_RS16695	COG1959	2 iron, 2 sulfur cluster binding
M1L34_RS16710	COG1301	dicarboxylic acid transport
M1L34_RS16715	COG1946	Acyl-CoA thioesterase
M1L34_RS16735	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
M1L34_RS16740	COG1040	competence protein
M1L34_RS16745	COG0494	nUDIX hydrolase
M1L34_RS16755	COG0598	Magnesium transport protein CorA
M1L34_RS16765	COG2854	intermembrane phospholipid transfer
M1L34_RS16775	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
M1L34_RS16780	COG1127	ABC transporter
M1L34_RS16790	COG0513	Belongs to the DEAD box helicase family
M1L34_RS16810	COG0408	coproporphyrinogen oxidase activity
M1L34_RS16825	COG1960	acyl-CoA dehydrogenase activity
M1L34_RS16835	COG1983	PspC domain protein
M1L34_RS16840	COG0517	IMP dehydrogenase activity
M1L34_RS16885	COG0583	DNA-binding transcription factor activity
M1L34_RS16925	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS16935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
M1L34_RS16940	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
M1L34_RS16945	COG0833	amino acid
M1L34_RS16975	COG1192	Involved in chromosome partitioning
M1L34_RS16980	COG0628	permease
M1L34_RS16990	COG1289	transmembrane transporter activity
M1L34_RS17005	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1L34_RS17010	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
M1L34_RS17020	COG0277	FAD linked oxidase domain protein
M1L34_RS17025	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
M1L34_RS17050	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
M1L34_RS17055	COG5380	lipid catabolic process
M1L34_RS17075	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
M1L34_RS17125	COG0194	GDP metabolic process
M1L34_RS17140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
M1L34_RS17160	COG3307	-O-antigen
M1L34_RS17180	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
M1L34_RS17185	COG1704	LemA family
M1L34_RS17195	COG0493	'glutamate synthase
M1L34_RS17200	COG0070	glutamate synthase
M1L34_RS17200	COG0069	glutamate synthase activity
M1L34_RS17200	COG0067	glutamate synthase
M1L34_RS17250	COG2226	methyltransferase
M1L34_RS17265	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
M1L34_RS17270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
M1L34_RS17315	COG0833	amino acid
M1L34_RS17380	COG0488	(ABC) transporter
M1L34_RS17385	COG2873	o-acetylhomoserine
M1L34_RS17390	COG4221	oxidoreductase activity
M1L34_RS17395	COG0659	secondary active sulfate transmembrane transporter activity
M1L34_RS17420	COG0427	acetyl-CoA hydrolase
M1L34_RS17450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
M1L34_RS17490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
M1L34_RS17545	COG2207	Transcriptional regulator
M1L34_RS17550	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
M1L34_RS17565	COG2249	NAD(P)H dehydrogenase (quinone) activity
M1L34_RS17570	COG1733	regulation of RNA biosynthetic process
M1L34_RS17585	COG1733	regulation of RNA biosynthetic process
M1L34_RS17605	COG0667	Aldo Keto reductase
M1L34_RS17630	COG0583	DNA-binding transcription factor activity
M1L34_RS17635	COG2814	Major facilitator Superfamily
M1L34_RS17665	COG1335	isochorismatase
M1L34_RS17675	COG1012	belongs to the aldehyde dehydrogenase family
M1L34_RS17680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
M1L34_RS17690	COG1113	amino acid transport
M1L34_RS17700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
M1L34_RS17715	COG2814	Major facilitator Superfamily
M1L34_RS17725	COG0351	phosphomethylpyrimidine kinase
M1L34_RS17725	COG0352	thiamine-phosphate diphosphorylase activity
M1L34_RS17725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
M1L34_RS17745	COG1309	transcriptional regulator
M1L34_RS17750	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
M1L34_RS17765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
M1L34_RS17775	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
M1L34_RS17780	COG3162	membrane
M1L34_RS17785	COG2198	Histidine kinase
M1L34_RS17785	COG2205	protein histidine kinase activity
M1L34_RS17785	COG0784	Response regulator, receiver
M1L34_RS17810	COG1522	sequence-specific DNA binding
M1L34_RS17815	COG1335	isochorismatase
M1L34_RS17820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
M1L34_RS17830	COG0668	transmembrane transport
M1L34_RS17835	COG1385	rRNA (uridine-N3-)-methyltransferase activity
M1L34_RS17840	COG1519	Transferase
M1L34_RS17845	COG1902	pentaerythritol trinitrate reductase activity
M1L34_RS17865	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
M1L34_RS17890	COG0426	domain, Protein
M1L34_RS17890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
M1L34_RS17895	COG4774	siderophore transport
M1L34_RS17900	COG2119	membrane
M1L34_RS17910	COG0508	dehydrogenase complex catalyzes the overall conversion of
M1L34_RS17920	COG4942	peptidase
M1L34_RS17935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
M1L34_RS17945	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
M1L34_RS17965	COG0189	ligase activity
M1L34_RS17985	COG0708	Exodeoxyribonuclease III
M1L34_RS17990	COG1393	Belongs to the ArsC family
M1L34_RS18045	COG2233	PERMEase
M1L34_RS18055	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
M1L34_RS18065	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
M1L34_RS18075	COG3150	esterase
M1L34_RS18105	COG3179	chitinase
M1L34_RS18130	COG2918	glutathione biosynthetic process
M1L34_RS18145	COG2733	membrane
M1L34_RS18150	COG0436	Aminotransferase
M1L34_RS18155	COG0534	Mate efflux family protein
M1L34_RS18215	COG0753	catalase activity
M1L34_RS18260	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
M1L34_RS18265	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
M1L34_RS18275	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
M1L34_RS18280	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
M1L34_RS18285	COG0546	phosphoglycolate phosphatase activity
M1L34_RS18295	COG0010	Belongs to the arginase family
M1L34_RS18325	COG2188	Transcriptional regulator
M1L34_RS18335	COG0523	cobalamin synthesis protein
M1L34_RS18345	COG1113	amino acid transport
M1L34_RS18355	COG0625	glutathione transferase activity
M1L34_RS18375	COG1683	Conserved Protein
M1L34_RS18380	COG0534	Mate efflux family protein
M1L34_RS18385	COG0385	Bile acid
M1L34_RS18390	COG1335	isochorismatase
M1L34_RS18395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
M1L34_RS18415	COG2116	formate transmembrane transporter activity
M1L34_RS18420	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
M1L34_RS18425	COG2133	pyrroloquinoline quinone binding
M1L34_RS18430	COG2983	Belongs to the UPF0260 family
M1L34_RS18450	COG1194	a g-specific adenine glycosylase
M1L34_RS18465	COG2818	Glycosylase
M1L34_RS18470	COG1064	alcohol dehydrogenase
M1L34_RS18475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
M1L34_RS18490	COG0583	DNA-binding transcription factor activity
M1L34_RS18495	COG0656	L-ascorbic acid biosynthetic process
M1L34_RS18500	COG2814	Major facilitator Superfamily
M1L34_RS18535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
M1L34_RS18550	COG2233	PERMEase
M1L34_RS18590	COG0733	neurotransmitter:sodium symporter activity