locus-tag	class	description
EGX84_RS00075	COG0477	Major facilitator Superfamily
EGX84_RS00080	COG0697	spore germination
EGX84_RS00145	COG0347	Belongs to the P(II) protein family
EGX84_RS00170	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
EGX84_RS00185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGX84_RS00185	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX84_RS00195	COG1373	ATPase (AAA superfamily
EGX84_RS00285	COG0004	ammonium transporteR
EGX84_RS00290	COG0004	ammonium transporteR
EGX84_RS00295	COG1396	sequence-specific DNA binding
EGX84_RS00305	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
EGX84_RS00310	COG2218	PFAM glutamate synthase alpha subunit domain protein
EGX84_RS00315	COG0069	glutamate synthase activity
EGX84_RS00335	COG0582	viral genome integration into host DNA
EGX84_RS00375	COG2815	serine threonine protein kinase
EGX84_RS00375	COG0515	serine threonine protein kinase
EGX84_RS00395	COG2072	flavoprotein involved in K transport
EGX84_RS00405	COG2144	transferase activity, transferring acyl groups
EGX84_RS00430	COG3604	Transcriptional regulator
EGX84_RS00455	COG1192	Involved in chromosome partitioning
EGX84_RS00460	COG1475	DNA binding
EGX84_RS00465	COG0404	The glycine cleavage system catalyzes the degradation of glycine
EGX84_RS00470	COG3850	Histidine kinase
EGX84_RS00475	COG2197	response regulator
EGX84_RS00495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX84_RS00505	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EGX84_RS00510	COG0745	RESPONSE REGULATOR receiver
EGX84_RS00515	COG2205	protein histidine kinase activity
EGX84_RS00525	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS00530	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS00580	COG1442	glycosyl transferase family 8
EGX84_RS00595	COG2826	transposase and inactivated derivatives, IS30 family
EGX84_RS00610	COG0438	transferase activity, transferring glycosyl groups
EGX84_RS00620	COG0438	transferase activity, transferring glycosyl groups
EGX84_RS00625	COG0726	polysaccharide deacetylase
EGX84_RS00640	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EGX84_RS00645	COG2205	protein histidine kinase activity
EGX84_RS00655	COG3646	Phage regulatory protein
EGX84_RS00685	COG4695	Portal protein
EGX84_RS00910	COG0629	single-stranded DNA binding
EGX84_RS00960	COG1862	Preprotein translocase
EGX84_RS00985	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGX84_RS00995	COG3781	membrane
EGX84_RS01000	COG0613	PHP domain protein
EGX84_RS01010	COG2350	Protein conserved in bacteria
EGX84_RS01040	COG1607	acyl-coa hydrolase
EGX84_RS01100	COG2199	diguanylate cyclase activity
EGX84_RS01110	COG1408	metallophosphoesterase
EGX84_RS01115	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGX84_RS01125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGX84_RS01145	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGX84_RS01150	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGX84_RS01155	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
EGX84_RS01165	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGX84_RS01175	COG2969	positive regulation of protein catabolic process
EGX84_RS01195	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS01200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGX84_RS01215	COG1309	transcriptional regulator
EGX84_RS01220	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS01265	COG1183	phosphatidylcholine synthase activity
EGX84_RS01270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGX84_RS01300	COG0739	heme binding
EGX84_RS01300	COG0741	lytic transglycosylase activity
EGX84_RS01300	COG1196	nuclear chromosome segregation
EGX84_RS01310	COG1702	phosphate starvation-inducible protein PhoH
EGX84_RS01345	COG1295	ribonuclease BN
EGX84_RS01365	COG2169	Transcriptional regulator
EGX84_RS01370	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGX84_RS01705	COG4695	Portal protein
EGX84_RS01725	COG0557	exoribonuclease II activity
EGX84_RS01730	COG0339	signal peptide processing
EGX84_RS01735	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EGX84_RS01765	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EGX84_RS01770	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS01925	COG0626	cystathionine gamma-synthase activity
EGX84_RS01930	COG0433	COG0433 Predicted ATPase
EGX84_RS01940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX84_RS01940	COG1017	nitric oxide dioxygenase activity
EGX84_RS01945	COG1959	2 iron, 2 sulfur cluster binding
EGX84_RS01960	COG1301	dicarboxylic acid transport
EGX84_RS01965	COG1946	Acyl-CoA thioesterase
EGX84_RS01985	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGX84_RS01990	COG1040	competence protein
EGX84_RS01995	COG0494	nUDIX hydrolase
EGX84_RS02005	COG0598	Magnesium transport protein CorA
EGX84_RS02015	COG2854	intermembrane phospholipid transfer
EGX84_RS02025	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGX84_RS02030	COG1127	ABC transporter
EGX84_RS02035	COG0513	Belongs to the DEAD box helicase family
EGX84_RS02055	COG0408	coproporphyrinogen oxidase activity
EGX84_RS02070	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS02080	COG1983	PspC domain protein
EGX84_RS02085	COG0517	IMP dehydrogenase activity
EGX84_RS02150	COG0583	DNA-binding transcription factor activity
EGX84_RS02190	COG1012	belongs to the aldehyde dehydrogenase family
EGX84_RS02200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGX84_RS02205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGX84_RS02210	COG0833	amino acid
EGX84_RS02240	COG1192	Involved in chromosome partitioning
EGX84_RS02245	COG0628	permease
EGX84_RS02255	COG1289	transmembrane transporter activity
EGX84_RS02270	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGX84_RS02275	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EGX84_RS02285	COG0277	FAD linked oxidase domain protein
EGX84_RS02290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGX84_RS02315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGX84_RS02320	COG5380	lipid catabolic process
EGX84_RS02340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGX84_RS02390	COG0194	GDP metabolic process
EGX84_RS02405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX84_RS02425	COG3307	-O-antigen
EGX84_RS02445	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EGX84_RS02450	COG1704	LemA family
EGX84_RS02460	COG0493	'glutamate synthase
EGX84_RS02465	COG0070	glutamate synthase
EGX84_RS02465	COG0067	glutamate synthase
EGX84_RS02465	COG0069	glutamate synthase activity
EGX84_RS02515	COG2226	methyltransferase
EGX84_RS02530	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGX84_RS02535	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGX84_RS02580	COG0833	amino acid
EGX84_RS02600	COG0582	viral genome integration into host DNA
EGX84_RS02710	COG0488	(ABC) transporter
EGX84_RS02720	COG4221	oxidoreductase activity
EGX84_RS02725	COG0659	secondary active sulfate transmembrane transporter activity
EGX84_RS02750	COG0427	acetyl-CoA hydrolase
EGX84_RS02780	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGX84_RS02810	COG2329	Antibiotic biosynthesis monooxygenase
EGX84_RS02825	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EGX84_RS02900	COG3328	transposase activity
EGX84_RS02925	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
EGX84_RS03020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGX84_RS03045	COG1335	isochorismatase
EGX84_RS03055	COG1012	belongs to the aldehyde dehydrogenase family
EGX84_RS03060	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGX84_RS03070	COG1113	amino acid transport
EGX84_RS03080	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGX84_RS03095	COG2814	Major facilitator Superfamily
EGX84_RS03105	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGX84_RS03105	COG0352	thiamine-phosphate diphosphorylase activity
EGX84_RS03105	COG0351	phosphomethylpyrimidine kinase
EGX84_RS03125	COG1309	transcriptional regulator
EGX84_RS03130	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGX84_RS03145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX84_RS03155	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX84_RS03160	COG3162	membrane
EGX84_RS03165	COG2205	protein histidine kinase activity
EGX84_RS03165	COG0784	Response regulator, receiver
EGX84_RS03165	COG2198	Histidine kinase
EGX84_RS03195	COG1335	isochorismatase
EGX84_RS03200	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGX84_RS03210	COG0668	transmembrane transport
EGX84_RS03215	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX84_RS03220	COG1519	Transferase
EGX84_RS03225	COG1902	pentaerythritol trinitrate reductase activity
EGX84_RS03245	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGX84_RS03270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX84_RS03270	COG0426	domain, Protein
EGX84_RS03275	COG4774	siderophore transport
EGX84_RS03280	COG2119	membrane
EGX84_RS03290	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX84_RS03300	COG4942	peptidase
EGX84_RS03315	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGX84_RS03325	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGX84_RS03345	COG0189	ligase activity
EGX84_RS03380	COG0708	Exodeoxyribonuclease III
EGX84_RS03385	COG1393	Belongs to the ArsC family
EGX84_RS03400	COG3706	GGDEF domain
EGX84_RS03435	COG2351	hydroxyisourate hydrolase activity
EGX84_RS03440	COG2233	PERMEase
EGX84_RS03450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX84_RS03460	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EGX84_RS03470	COG3150	esterase
EGX84_RS03545	COG2826	transposase and inactivated derivatives, IS30 family
EGX84_RS03565	COG2918	glutathione biosynthetic process
EGX84_RS03580	COG2733	membrane
EGX84_RS03585	COG0436	Aminotransferase
EGX84_RS03590	COG0534	Mate efflux family protein
EGX84_RS03685	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGX84_RS03690	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGX84_RS03700	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGX84_RS03775	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGX84_RS03855	COG0010	Belongs to the arginase family
EGX84_RS03885	COG2188	Transcriptional regulator
EGX84_RS03895	COG0523	cobalamin synthesis protein
EGX84_RS03905	COG1113	amino acid transport
EGX84_RS03915	COG0625	glutathione transferase activity
EGX84_RS03935	COG1683	Conserved Protein
EGX84_RS03940	COG0534	Mate efflux family protein
EGX84_RS03945	COG0385	Bile acid
EGX84_RS03950	COG1335	isochorismatase
EGX84_RS03955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX84_RS03975	COG2116	formate transmembrane transporter activity
EGX84_RS03980	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGX84_RS03985	COG2133	pyrroloquinoline quinone binding
EGX84_RS03990	COG2983	Belongs to the UPF0260 family
EGX84_RS04010	COG1194	a g-specific adenine glycosylase
EGX84_RS04025	COG2818	Glycosylase
EGX84_RS04030	COG1064	alcohol dehydrogenase
EGX84_RS04035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX84_RS04055	COG0583	DNA-binding transcription factor activity
EGX84_RS04060	COG0656	L-ascorbic acid biosynthetic process
EGX84_RS04065	COG2814	Major facilitator Superfamily
EGX84_RS04100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX84_RS04115	COG2233	PERMEase
EGX84_RS04120	COG0583	DNA-binding transcription factor activity
EGX84_RS04155	COG0733	neurotransmitter:sodium symporter activity
EGX84_RS04170	COG3293	Transposase
EGX84_RS04220	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGX84_RS04225	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EGX84_RS04230	COG0596	Alpha beta hydrolase
EGX84_RS04255	COG0488	(ABC) transporter
EGX84_RS04260	COG0586	Pfam SNARE associated Golgi protein
EGX84_RS04270	COG0187	DNA topoisomerase II activity
EGX84_RS04280	COG0592	DNA-directed DNA polymerase activity
EGX84_RS04305	COG0706	membrane insertase activity
EGX84_RS04320	COG1230	cation diffusion facilitator family transporter
EGX84_RS04325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX84_RS04340	COG0402	S-adenosylhomocysteine deaminase activity
EGX84_RS04350	COG0754	glutathionylspermidine amidase activity
EGX84_RS04375	COG0671	phosphoesterase, PA-phosphatase related
EGX84_RS04385	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGX84_RS04405	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGX84_RS04410	COG2951	lytic endotransglycosylase activity
EGX84_RS04460	COG0657	acetylesterase activity
EGX84_RS04465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGX84_RS04505	COG1047	Peptidyl-prolyl cis-trans
EGX84_RS04515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGX84_RS04520	COG0196	riboflavin kinase activity
EGX84_RS04530	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGX84_RS04535	COG3328	transposase activity
EGX84_RS04540	COG1309	transcriptional regulator
EGX84_RS04545	COG1116	anion transmembrane transporter activity
EGX84_RS04550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX84_RS04555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX84_RS04580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX84_RS04600	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS04605	COG0546	phosphoglycolate phosphatase activity
EGX84_RS04660	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGX84_RS04665	COG0728	peptidoglycan biosynthetic process
EGX84_RS04690	COG1596	polysaccharide export
EGX84_RS04695	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGX84_RS04705	COG1442	glycosyl transferase family 8
EGX84_RS04705	COG1216	Glycosyl transferase, family 2
EGX84_RS04710	COG0438	transferase activity, transferring glycosyl groups
EGX84_RS04720	COG0438	transferase activity, transferring glycosyl groups
EGX84_RS04730	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGX84_RS04735	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGX84_RS04750	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGX84_RS04760	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGX84_RS04780	COG2186	Transcriptional regulator
EGX84_RS04790	COG0277	FAD linked oxidase domain protein
EGX84_RS04795	COG1448	Aminotransferase
EGX84_RS04805	COG1802	Transcriptional regulator
EGX84_RS04820	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGX84_RS04850	COG0564	pseudouridine synthase activity
EGX84_RS04890	COG0251	oxidation-reduction process
EGX84_RS04895	COG1113	amino acid transport
EGX84_RS04900	COG1113	amino acid transport
EGX84_RS04925	COG1538	Outer membrane efflux protein
EGX84_RS04930	COG1132	(ABC) transporter
EGX84_RS04995	COG4115	mRNA cleavage
EGX84_RS05005	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
EGX84_RS05065	COG4245	von Willebrand factor, type A
EGX84_RS05075	COG4245	von Willebrand factor, type A
EGX84_RS05100	COG1358	cellular component organization or biogenesis
EGX84_RS05140	COG2304	oxidoreductase activity
EGX84_RS05180	COG3756	Protein conserved in bacteria
EGX84_RS05215	COG0271	Belongs to the BolA IbaG family
EGX84_RS05225	COG1192	Involved in chromosome partitioning
EGX84_RS05240	COG0586	Pfam SNARE associated Golgi protein
EGX84_RS05245	COG2259	Doxx family
EGX84_RS05250	COG4399	Belongs to the UPF0754 family
EGX84_RS05255	COG0519	Catalyzes the synthesis of GMP from XMP
EGX84_RS05255	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGX84_RS05300	COG0281	malic enzyme
EGX84_RS05305	COG2837	iron assimilation
EGX84_RS05310	COG1280	lysine exporter protein (LysE YggA)
EGX84_RS05315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGX84_RS05320	COG1121	(ABC) transporter
EGX84_RS05385	COG0386	Belongs to the glutathione peroxidase family
EGX84_RS05400	COG1309	transcriptional regulator
EGX84_RS05405	COG0697	spore germination
EGX84_RS05415	COG0758	DNA mediated transformation
EGX84_RS05485	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGX84_RS05495	COG0655	NAD(P)H dehydrogenase (quinone) activity
EGX84_RS05535	COG4452	Inner membrane protein CreD
EGX84_RS05540	COG2205	protein histidine kinase activity
EGX84_RS05545	COG0745	RESPONSE REGULATOR receiver
EGX84_RS05550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGX84_RS05560	COG2814	Major facilitator Superfamily
EGX84_RS05570	COG1253	flavin adenine dinucleotide binding
EGX84_RS05575	COG3012	SEC-C Motif Domain Protein
EGX84_RS05580	COG2860	membrane
EGX84_RS05585	COG0477	Major facilitator Superfamily
EGX84_RS05595	COG0318	PFAM AMP-dependent synthetase and ligase
EGX84_RS05610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGX84_RS05625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGX84_RS05630	COG0235	Class ii aldolase
EGX84_RS05645	COG0606	chelatase, subunit chli
EGX84_RS05655	COG0347	Belongs to the P(II) protein family
EGX84_RS05660	COG0004	ammonium transporteR
EGX84_RS05670	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX84_RS05670	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGX84_RS05710	COG0795	lipopolysaccharide-transporting ATPase activity
EGX84_RS05715	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EGX84_RS05720	COG0793	Belongs to the peptidase S41A family
EGX84_RS05735	COG2197	response regulator
EGX84_RS05745	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGX84_RS05755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX84_RS05760	COG4974	Belongs to the 'phage' integrase family
EGX84_RS05785	COG0772	Belongs to the SEDS family
EGX84_RS05790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX84_RS05795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGX84_RS05800	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGX84_RS05825	COG0697	spore germination
EGX84_RS05830	COG1538	Outer membrane efflux protein
EGX84_RS05850	COG3275	phosphorelay sensor kinase activity
EGX84_RS05860	COG0181	hydroxymethylbilane synthase activity
EGX84_RS05905	COG1716	ATPase activity
EGX84_RS05910	COG0546	phosphoglycolate phosphatase activity
EGX84_RS06005	COG0596	Alpha beta hydrolase
EGX84_RS06010	COG2056	Na+-H+ antiporter family
EGX84_RS06030	COG0326	Molecular chaperone. Has ATPase activity
EGX84_RS06115	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGX84_RS06120	COG2169	Transcriptional regulator
EGX84_RS06120	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX84_RS06150	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGX84_RS06160	COG0497	DNA recombination
EGX84_RS06175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX84_RS06185	COG0237	dephospho-CoA kinase activity
EGX84_RS06235	COG0195	Participates in both transcription termination and antitermination
EGX84_RS06250	COG1320	monovalent cation:proton antiporter activity
EGX84_RS06255	COG2212	antiporter activity
EGX84_RS06260	COG1863	multisubunit Na H antiporter MnhE subunit
EGX84_RS06265	COG0651	ATP synthesis coupled electron transport
EGX84_RS06270	COG1006	Multisubunit Na H antiporter MnhC subunit
EGX84_RS06275	COG2111	Na H antiporter
EGX84_RS06275	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX84_RS06290	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGX84_RS06310	COG2226	methyltransferase
EGX84_RS06330	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGX84_RS06335	COG1074	ATP-dependent DNA helicase activity
EGX84_RS06340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX84_RS06345	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGX84_RS06360	COG0598	Magnesium transport protein CorA
EGX84_RS06365	COG0789	Transcriptional regulator
EGX84_RS06370	COG0484	heat shock protein binding
EGX84_RS06385	COG0475	glutathione-regulated potassium exporter activity
EGX84_RS06385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX84_RS06390	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGX84_RS06410	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX84_RS06420	COG4535	Mg2 and Co2 transporter CorC
EGX84_RS06425	COG0425	Belongs to the sulfur carrier protein TusA family
EGX84_RS06435	COG0644	oxidoreductase
EGX84_RS06435	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EGX84_RS06445	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGX84_RS06460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX84_RS06465	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EGX84_RS06500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGX84_RS06515	COG0534	Mate efflux family protein
EGX84_RS06525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGX84_RS06530	COG4221	oxidoreductase activity
EGX84_RS06535	COG0583	DNA-binding transcription factor activity
EGX84_RS06550	COG0318	PFAM AMP-dependent synthetase and ligase
EGX84_RS06555	COG1530	ribonuclease E activity
EGX84_RS06570	COG0546	phosphoglycolate phosphatase activity
EGX84_RS06575	COG2378	regulation of single-species biofilm formation
EGX84_RS06590	COG0583	DNA-binding transcription factor activity
EGX84_RS06620	COG0583	DNA-binding transcription factor activity
EGX84_RS06645	COG0473	3-isopropylmalate dehydrogenase activity
EGX84_RS06700	COG1301	dicarboxylic acid transport
EGX84_RS06710	COG1560	Kdo2-lipid A biosynthetic process
EGX84_RS06715	COG1280	lysine exporter protein (LysE YggA)
EGX84_RS06725	COG0488	(ABC) transporter
EGX84_RS06730	COG2900	Belongs to the SlyX family
EGX84_RS06740	COG1733	regulation of RNA biosynthetic process
EGX84_RS06765	COG0210	DNA helicase
EGX84_RS06770	COG0724	RNA recognition motif
EGX84_RS06790	COG4651	solute:proton antiporter activity
EGX84_RS06790	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGX84_RS06815	COG0788	formyltetrahydrofolate deformylase activity
EGX84_RS06915	COG2813	Specifically methylates the guanine in position
EGX84_RS06915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGX84_RS06925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGX84_RS06935	COG4774	siderophore transport
EGX84_RS06945	COG0740	serine-type endopeptidase activity
EGX84_RS06965	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX84_RS06965	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX84_RS06970	COG0280	phosphate acetyltransferase
EGX84_RS06970	COG0857	belongs to the CobB CobQ family
EGX84_RS06975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGX84_RS06985	COG0800	Aldolase
EGX84_RS06995	COG3265	gluconokinase activity
EGX84_RS07000	COG1012	belongs to the aldehyde dehydrogenase family
EGX84_RS07010	COG2267	carboxylic ester hydrolase activity
EGX84_RS07025	COG0793	Belongs to the peptidase S41A family
EGX84_RS07060	COG1426	Protein conserved in bacteria
EGX84_RS07100	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGX84_RS07110	COG1162	GTPase activity
EGX84_RS07115	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGX84_RS07130	COG1538	Outer membrane efflux protein
EGX84_RS07135	COG1136	(ABC) transporter
EGX84_RS07135	COG0577	efflux transmembrane transporter activity
EGX84_RS07140	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX84_RS07165	COG0028	Belongs to the TPP enzyme family
EGX84_RS07170	COG0440	acetolactate synthase activity
EGX84_RS07210	COG0484	heat shock protein binding
EGX84_RS07355	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGX84_RS07370	COG0084	hydrolase, TatD family'
EGX84_RS07380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGX84_RS07410	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX84_RS07475	COG2205	protein histidine kinase activity
EGX84_RS07540	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX84_RS07575	COG0640	Transcriptional regulator
EGX84_RS07615	COG2814	Major facilitator Superfamily
EGX84_RS07625	COG0697	spore germination
EGX84_RS07655	COG3622	Belongs to the hyi family
EGX84_RS07660	COG2084	Dehydrogenase
EGX84_RS07665	COG1024	Enoyl-CoA hydratase
EGX84_RS07670	COG0784	Response regulator, receiver
EGX84_RS07670	COG5002	protein histidine kinase activity
EGX84_RS07670	COG2205	protein histidine kinase activity
EGX84_RS07690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGX84_RS07700	COG3956	TIGRFAM MazG family protein
EGX84_RS07705	COG1555	photosystem II stabilization
EGX84_RS07710	COG0617	tRNA 3'-terminal CCA addition
EGX84_RS07715	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGX84_RS07735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX84_RS07740	COG3028	Belongs to the UPF0307 family
EGX84_RS07745	COG0318	PFAM AMP-dependent synthetase and ligase
EGX84_RS07765	COG0625	glutathione transferase activity
EGX84_RS07770	COG1238	metal cluster binding
EGX84_RS07810	COG0072	phenylalanine-tRNA ligase activity
EGX84_RS07840	COG0248	Ppx GppA phosphatase
EGX84_RS07850	COG0037	tRNA processing
EGX84_RS07890	COG1764	response to oxidative stress
EGX84_RS07895	COG1846	Transcriptional regulator
EGX84_RS07905	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX84_RS07965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGX84_RS07970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EGX84_RS07975	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGX84_RS07985	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EGX84_RS08025	COG1214	PFAM Peptidase M22, glycoprotease
EGX84_RS08050	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGX84_RS08055	COG0561	phosphatase activity
EGX84_RS08065	COG2132	Multicopper oxidase
EGX84_RS08070	COG3667	copper resistance
EGX84_RS08085	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGX84_RS08090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EGX84_RS08095	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EGX84_RS08125	COG1063	alcohol dehydrogenase
EGX84_RS08130	COG0583	DNA-binding transcription factor activity
EGX84_RS08135	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS08140	COG2814	Major facilitator Superfamily
EGX84_RS08145	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGX84_RS08150	COG1309	transcriptional regulator
EGX84_RS08165	COG1053	succinate dehydrogenase
EGX84_RS08170	COG0583	DNA-binding transcription factor activity
EGX84_RS08190	COG0583	DNA-binding transcription factor activity
EGX84_RS08200	COG0583	DNA-binding transcription factor activity
EGX84_RS08215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX84_RS08240	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGX84_RS08260	COG0745	RESPONSE REGULATOR receiver
EGX84_RS08275	COG3706	GGDEF domain
EGX84_RS08300	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EGX84_RS08330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGX84_RS08335	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGX84_RS08355	COG0583	DNA-binding transcription factor activity
EGX84_RS08375	COG0668	transmembrane transport
EGX84_RS08385	COG2081	HI0933 family
EGX84_RS08390	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EGX84_RS08420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX84_RS08420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGX84_RS08430	COG0489	protein tyrosine kinase activity
EGX84_RS08490	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGX84_RS08500	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGX84_RS08515	COG0730	response to heat
EGX84_RS08525	COG1196	nuclear chromosome segregation
EGX84_RS08545	COG2223	nitrite transmembrane transporter activity
EGX84_RS08550	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EGX84_RS08555	COG1877	trehalose-phosphatase activity
EGX84_RS08560	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGX84_RS08560	COG0596	Alpha beta hydrolase
EGX84_RS08560	COG2226	methyltransferase
EGX84_RS08575	COG4106	trans-aconitate 2-methyltransferase activity
EGX84_RS08590	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGX84_RS08595	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EGX84_RS08600	COG0009	L-threonylcarbamoyladenylate synthase
EGX84_RS08605	COG3101	peptidyl-lysine hydroxylation
EGX84_RS08610	COG1399	metal-binding, possibly nucleic acid-binding protein
EGX84_RS08635	COG1652	LysM domain
EGX84_RS08640	COG0352	thiamine-phosphate diphosphorylase activity
EGX84_RS08640	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGX84_RS08640	COG0351	phosphomethylpyrimidine kinase
EGX84_RS08650	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGX84_RS08690	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX84_RS08720	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EGX84_RS08735	COG0358	DNA primase activity
EGX84_RS08745	COG0564	pseudouridine synthase activity
EGX84_RS08770	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX84_RS08790	COG0583	DNA-binding transcription factor activity
EGX84_RS08795	COG0473	3-isopropylmalate dehydrogenase activity
EGX84_RS08805	COG0657	acetylesterase activity
EGX84_RS08815	COG1012	belongs to the aldehyde dehydrogenase family
EGX84_RS08835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGX84_RS08835	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGX84_RS08850	COG1981	membrane
EGX84_RS08895	COG0456	acetyltransferase
EGX84_RS08905	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EGX84_RS08910	COG0492	ferredoxin-NADP+ reductase activity
EGX84_RS08915	COG1674	ftsk spoiiie
EGX84_RS08915	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGX84_RS08920	COG1280	lysine exporter protein (LysE YggA)
EGX84_RS08935	COG2894	cell division
EGX84_RS08950	COG0204	Acyl-transferase
EGX84_RS08955	COG2885	chlorophyll binding
EGX84_RS08960	COG0210	DNA helicase
EGX84_RS08970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGX84_RS08985	COG0121	glutamine amidotransferase
EGX84_RS09015	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGX84_RS09020	COG0735	belongs to the Fur family
EGX84_RS09045	COG0420	3'-5' exonuclease activity
EGX84_RS09065	COG1090	epimerase
EGX84_RS09080	COG2050	protein possibly involved in aromatic compounds catabolism
EGX84_RS09090	COG2814	Major facilitator Superfamily
EGX84_RS09095	COG0405	Gamma-glutamyltransferase
EGX84_RS09105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX84_RS09110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGX84_RS09125	COG1607	acyl-coa hydrolase
EGX84_RS09135	COG0523	cobalamin synthesis protein
EGX84_RS09155	COG4681	YaeQ
EGX84_RS09165	COG0726	polysaccharide deacetylase
EGX84_RS09165	COG1649	PFAM Uncharacterised BCR, COG1649
EGX84_RS09170	COG1215	transferase activity, transferring glycosyl groups
EGX84_RS09180	COG1024	Enoyl-CoA hydratase
EGX84_RS09195	COG1414	Transcriptional regulator
EGX84_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS09230	COG2271	Major facilitator Superfamily
EGX84_RS09240	COG2267	carboxylic ester hydrolase activity
EGX84_RS09245	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS09260	COG0028	Belongs to the TPP enzyme family
EGX84_RS09270	COG0477	Major facilitator Superfamily
EGX84_RS09275	COG0242	peptide deformylase activity
EGX84_RS09280	COG2066	Belongs to the glutaminase family
EGX84_RS09285	COG2207	Transcriptional regulator
EGX84_RS09290	COG2223	nitrite transmembrane transporter activity
EGX84_RS09310	COG0583	DNA-binding transcription factor activity
EGX84_RS09315	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS09320	COG2271	Major facilitator Superfamily
EGX84_RS09325	COG3959	Transketolase, thiamine diphosphate binding domain
EGX84_RS09330	COG3958	Transketolase
EGX84_RS09355	COG0306	phosphate transporter
EGX84_RS09375	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGX84_RS09420	COG4181	ATPase activity
EGX84_RS09425	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EGX84_RS09455	COG0583	DNA-binding transcription factor activity
EGX84_RS09465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX84_RS09470	COG1773	rubredoxin
EGX84_RS09520	COG2851	Citrate transporter
EGX84_RS09530	COG1253	flavin adenine dinucleotide binding
EGX84_RS09570	COG0804	urea catabolic process
EGX84_RS09580	COG0830	nickel cation binding
EGX84_RS09595	COG0742	ribosomal rna small subunit methyltransferase
EGX84_RS09600	COG0768	penicillin binding
EGX84_RS09625	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGX84_RS09630	COG2878	Part of a membrane complex involved in electron transport
EGX84_RS09635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGX84_RS09645	COG3384	dioxygenase
EGX84_RS09665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGX84_RS09705	COG0006	proline dipeptidase activity
EGX84_RS09710	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX84_RS09715	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGX84_RS09735	COG1279	arginine transmembrane transporter activity
EGX84_RS09740	COG0583	DNA-binding transcription factor activity
EGX84_RS09785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX84_RS09790	COG0741	lytic transglycosylase activity
EGX84_RS09790	COG1388	LysM domain
EGX84_RS09790	COG1388	LysM domain
EGX84_RS09790	COG0741	lytic transglycosylase activity
EGX84_RS09800	COG4174	ABC transporter (Permease)
EGX84_RS09805	COG4239	(ABC) transporter, permease
EGX84_RS09810	COG4172	Belongs to the ABC transporter superfamily
EGX84_RS09840	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGX84_RS09850	COG2203	Gaf domain
EGX84_RS09850	COG5001	Diguanylate cyclase
EGX84_RS09850	COG3706	GGDEF domain
EGX84_RS09850	COG4251	negative regulation of phosphorylation
EGX84_RS09860	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX84_RS09860	COG1902	pentaerythritol trinitrate reductase activity
EGX84_RS09900	COG1113	amino acid transport
EGX84_RS09910	COG0531	amino acid
EGX84_RS09930	COG1012	belongs to the aldehyde dehydrogenase family
EGX84_RS09960	COG1113	amino acid transport
EGX84_RS09975	COG0697	spore germination
EGX84_RS09980	COG2721	sulfolactate sulfo-lyase activity
EGX84_RS09985	COG2271	Major facilitator Superfamily
EGX84_RS09990	COG4948	Mandelate Racemase Muconate Lactonizing
EGX84_RS10000	COG1012	belongs to the aldehyde dehydrogenase family
EGX84_RS10005	COG2186	Transcriptional regulator
EGX84_RS10030	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS10040	COG1012	belongs to the aldehyde dehydrogenase family
EGX84_RS10045	COG1024	Enoyl-CoA hydratase
EGX84_RS10050	COG2814	Major facilitator Superfamily
EGX84_RS10065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX84_RS10080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGX84_RS10125	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGX84_RS10140	COG0583	DNA-binding transcription factor activity
EGX84_RS10145	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGX84_RS10150	COG2072	flavoprotein involved in K transport
EGX84_RS10155	COG0300	oxidoreductase activity
EGX84_RS10165	COG1309	transcriptional regulator
EGX84_RS10170	COG1741	Belongs to the pirin family
EGX84_RS10185	COG2072	flavoprotein involved in K transport
EGX84_RS10195	COG2252	PERMEase
EGX84_RS10200	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EGX84_RS10215	COG2801	Transposase and inactivated derivatives
EGX84_RS10225	COG3038	cytochrome b561
EGX84_RS10235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGX84_RS10245	COG0527	aspartate kinase activity
EGX84_RS10255	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGX84_RS10265	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGX84_RS10280	COG0667	Aldo Keto reductase
EGX84_RS10290	COG1765	OsmC-like protein
EGX84_RS10305	COG0542	response to heat
EGX84_RS10340	COG2885	chlorophyll binding
EGX84_RS10350	COG0625	glutathione transferase activity
EGX84_RS10355	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGX84_RS10375	COG3634	alkyl hydroperoxide reductase activity
EGX84_RS10385	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EGX84_RS10395	COG0450	alkyl hydroperoxide reductase
EGX84_RS10400	COG1643	Atp-dependent helicase
EGX84_RS10415	COG2814	Major facilitator Superfamily
EGX84_RS10420	COG3135	benzoate transporter
EGX84_RS10425	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS10430	COG0543	2 iron, 2 sulfur cluster binding
EGX84_RS10430	COG0633	Ferredoxin
EGX84_RS10435	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EGX84_RS10455	COG0583	DNA-binding transcription factor activity
EGX84_RS10465	COG2871	sodium ion transport
EGX84_RS10550	COG1570	exodeoxyribonuclease VII activity
EGX84_RS10585	COG1280	lysine exporter protein (LysE YggA)
EGX84_RS10590	COG1278	Cold shock
EGX84_RS10660	COG0517	IMP dehydrogenase activity
EGX84_RS10660	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EGX84_RS10665	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGX84_RS10675	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EGX84_RS10680	COG1137	ATPase activity
EGX84_RS10685	COG1538	Outer membrane efflux protein
EGX84_RS10715	COG4122	O-methyltransferase activity
EGX84_RS10725	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGX84_RS10760	COG0598	Magnesium transport protein CorA
EGX84_RS10785	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGX84_RS10865	COG0583	DNA-binding transcription factor activity
EGX84_RS10870	COG1914	H( )-stimulated, divalent metal cation uptake system
EGX84_RS10890	COG4770	biotin carboxylase activity
EGX84_RS10895	COG0038	chloride channel
EGX84_RS10965	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS10995	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGX84_RS11015	COG2205	protein histidine kinase activity
EGX84_RS11015	COG0784	Response regulator, receiver
EGX84_RS11055	COG0765	amino acid transport
EGX84_RS11060	COG0765	amino acid transport
EGX84_RS11065	COG1126	abc transporter atp-binding protein
EGX84_RS11080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGX84_RS11100	COG1280	lysine exporter protein (LysE YggA)
EGX84_RS11105	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGX84_RS11110	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGX84_RS11115	COG1045	serine acetyltransferase
EGX84_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS11130	COG0583	DNA-binding transcription factor activity
EGX84_RS11135	COG0625	glutathione transferase activity
EGX84_RS11140	COG0625	glutathione transferase activity
EGX84_RS11145	COG0583	DNA-binding transcription factor activity
EGX84_RS11155	COG1346	cytolysis
EGX84_RS11175	COG2814	Major facilitator Superfamily
EGX84_RS11185	COG0583	DNA-binding transcription factor activity
EGX84_RS11195	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EGX84_RS11200	COG3052	prosthetic group binding
EGX84_RS11220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGX84_RS11240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGX84_RS11250	COG1294	oxidase, subunit
EGX84_RS11255	COG1271	oxidase subunit
EGX84_RS11290	COG0477	Major facilitator Superfamily
EGX84_RS11300	COG4521	taurine ABC transporter
EGX84_RS11305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EGX84_RS11310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX84_RS11315	COG2175	clavaminate synthase activity
EGX84_RS11325	COG1953	Uracil, thiamine, allantoin
EGX84_RS11345	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EGX84_RS11360	COG0640	Transcriptional regulator
EGX84_RS11365	COG0798	PFAM Bile acid sodium symporter
EGX84_RS11370	COG0583	DNA-binding transcription factor activity
EGX84_RS11385	COG3634	alkyl hydroperoxide reductase activity
EGX84_RS11420	COG2826	transposase and inactivated derivatives, IS30 family
EGX84_RS11425	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EGX84_RS11450	COG0436	Aminotransferase
EGX84_RS11460	COG0386	Belongs to the glutathione peroxidase family
EGX84_RS11500	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGX84_RS11525	COG0012	GTP binding
EGX84_RS11530	COG2011	ABC-type metal ion transport system permease component
EGX84_RS11535	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGX84_RS11545	COG1464	Belongs to the NlpA lipoprotein family
EGX84_RS11575	COG0765	amino acid transport
EGX84_RS11580	COG0765	amino acid transport
EGX84_RS11585	COG1126	abc transporter atp-binding protein
EGX84_RS11595	COG1522	sequence-specific DNA binding
EGX84_RS11610	COG1309	transcriptional regulator
EGX84_RS11650	COG0697	spore germination
EGX84_RS11705	COG3539	Fimbrial protein
EGX84_RS11730	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGX84_RS11730	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGX84_RS11775	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGX84_RS11785	COG2353	YceI-like domain
EGX84_RS11795	COG3698	Phosphodiester glycosidase
EGX84_RS11810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EGX84_RS11815	COG0506	proline dehydrogenase activity
EGX84_RS11815	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX84_RS11815	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGX84_RS11825	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGX84_RS11830	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGX84_RS11850	COG1132	(ABC) transporter
EGX84_RS11855	COG3122	Protein conserved in bacteria
EGX84_RS11860	COG3619	membrane
EGX84_RS11870	COG0640	Transcriptional regulator
EGX84_RS11880	COG2850	peptidyl-arginine hydroxylation
EGX84_RS11885	COG0424	maF-like protein
EGX84_RS11905	COG0191	fructose-bisphosphate aldolase activity
EGX84_RS11910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX84_RS11925	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EGX84_RS11935	COG1192	Involved in chromosome partitioning
EGX84_RS11940	COG1475	DNA binding
EGX84_RS11945	COG0811	peptide transport
EGX84_RS11955	COG1132	(ABC) transporter
EGX84_RS11960	COG1663	tetraacyldisaccharide 4'-kinase activity
EGX84_RS11980	COG0084	hydrolase, TatD family'
EGX84_RS12045	COG0776	regulation of translation
EGX84_RS12090	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGX84_RS12160	COG0305	Participates in initiation and elongation during chromosome replication
EGX84_RS12255	COG4695	Portal protein
EGX84_RS12395	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGX84_RS12445	COG0339	signal peptide processing
EGX84_RS12450	COG0601	transmembrane transport
EGX84_RS12455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGX84_RS12490	COG0702	epimerase
EGX84_RS12495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGX84_RS12515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGX84_RS12545	COG0316	Belongs to the HesB IscA family
EGX84_RS12550	COG0822	iron-sulfur transferase activity
EGX84_RS12575	COG0776	regulation of translation
EGX84_RS12580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGX84_RS12590	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGX84_RS12595	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS12600	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS12615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGX84_RS12650	COG4264	IucA IucC family
EGX84_RS12660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGX84_RS12700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGX84_RS12715	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EGX84_RS12720	COG0406	alpha-ribazole phosphatase activity
EGX84_RS12735	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGX84_RS12740	COG0730	response to heat
EGX84_RS12765	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGX84_RS12780	COG1131	(ABC) transporter
EGX84_RS12785	COG0842	Transport permease protein
EGX84_RS12790	COG0842	Transport permease protein
EGX84_RS12850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGX84_RS12860	COG0133	tryptophan synthase activity
EGX84_RS12890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGX84_RS12895	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGX84_RS12900	COG0022	dehydrogenase e1 component
EGX84_RS12905	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGX84_RS12910	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX84_RS12920	COG1063	alcohol dehydrogenase
EGX84_RS12925	COG3781	membrane
EGX84_RS12935	COG3453	Protein conserved in bacteria
EGX84_RS12935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX84_RS12945	COG0730	response to heat
EGX84_RS12960	COG3708	Transcriptional regulator
EGX84_RS12960	COG2207	Transcriptional regulator
EGX84_RS12965	COG1733	regulation of RNA biosynthetic process
EGX84_RS12970	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGX84_RS12980	COG2188	Transcriptional regulator
EGX84_RS12995	COG4521	taurine ABC transporter
EGX84_RS13000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGX84_RS13020	COG0477	Major facilitator Superfamily
EGX84_RS13035	COG1027	Aspartate ammonia-lyase
EGX84_RS13040	COG0583	DNA-binding transcription factor activity
EGX84_RS13045	COG0583	DNA-binding transcription factor activity
EGX84_RS13050	COG0183	Belongs to the thiolase family
EGX84_RS13055	COG2031	fatty acid transporter
EGX84_RS13080	COG0583	DNA-binding transcription factor activity
EGX84_RS13100	COG1309	transcriptional regulator
EGX84_RS13115	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS13120	COG2207	Transcriptional regulator
EGX84_RS13145	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS13155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX84_RS13205	COG0747	negative chemotaxis
EGX84_RS13235	COG1132	(ABC) transporter
EGX84_RS13240	COG1132	(ABC) transporter
EGX84_RS13270	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX84_RS13275	COG3657	addiction module killer protein
EGX84_RS13305	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EGX84_RS13330	COG1902	pentaerythritol trinitrate reductase activity
EGX84_RS13340	COG1309	transcriptional regulator
EGX84_RS13360	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
EGX84_RS13365	COG2801	Transposase and inactivated derivatives
EGX84_RS13435	COG2801	Transposase and inactivated derivatives
EGX84_RS13510	COG0745	RESPONSE REGULATOR receiver
EGX84_RS13530	COG2207	Transcriptional regulator
EGX84_RS13545	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS13620	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EGX84_RS13680	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGX84_RS13700	COG1120	ATPase activity
EGX84_RS13705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX84_RS13715	COG1064	alcohol dehydrogenase
EGX84_RS13745	COG0154	amidase activity
EGX84_RS13755	COG2814	Major facilitator Superfamily
EGX84_RS13780	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS13785	COG0583	DNA-binding transcription factor activity
EGX84_RS13790	COG1414	Transcriptional regulator
EGX84_RS13805	COG2391	methyltransferase activity
EGX84_RS13815	COG4993	Dehydrogenase
EGX84_RS13820	COG3659	wide pore channel activity
EGX84_RS13825	COG3420	alginic acid biosynthetic process
EGX84_RS13830	COG0710	3-dehydroquinate dehydratase activity
EGX84_RS13835	COG3485	protocatechuate 3,4-dioxygenase
EGX84_RS13840	COG3485	protocatechuate 3,4-dioxygenase
EGX84_RS13845	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGX84_RS13850	COG2271	Major facilitator Superfamily
EGX84_RS13855	COG0596	Alpha beta hydrolase
EGX84_RS13860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGX84_RS13865	COG0183	Belongs to the thiolase family
EGX84_RS13870	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EGX84_RS13875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGX84_RS13885	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EGX84_RS13890	COG2323	membrane
EGX84_RS13935	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGX84_RS13935	COG1902	pentaerythritol trinitrate reductase activity
EGX84_RS13960	COG0542	response to heat
EGX84_RS13965	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EGX84_RS14005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGX84_RS14010	COG0569	domain protein
EGX84_RS14055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGX84_RS14065	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGX84_RS14085	COG1294	oxidase, subunit
EGX84_RS14090	COG4890	Cyd operon protein YbgT
EGX84_RS14100	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EGX84_RS14110	COG0552	protein localization to endoplasmic reticulum
EGX84_RS14140	COG0516	GMP reductase activity
EGX84_RS14140	COG0517	IMP dehydrogenase activity
EGX84_RS14145	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGX84_RS14150	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGX84_RS14160	COG0583	DNA-binding transcription factor activity
EGX84_RS14165	COG0024	Methionine aminopeptidase
EGX84_RS14195	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGX84_RS14195	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGX84_RS14200	COG1105	Belongs to the carbohydrate kinase PfkB family
EGX84_RS14205	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX84_RS14205	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGX84_RS14205	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EGX84_RS14275	COG1113	amino acid transport
EGX84_RS14285	COG1522	sequence-specific DNA binding
EGX84_RS14310	COG1011	Hydrolase
EGX84_RS14315	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGX84_RS14325	COG2137	regulation of response to DNA damage stimulus
EGX84_RS14340	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGX84_RS14375	COG0575	Belongs to the CDS family
EGX84_RS14380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGX84_RS14405	COG3852	Histidine kinase
EGX84_RS14410	COG2204	response regulator
EGX84_RS14480	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGX84_RS14485	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EGX84_RS14505	COG0697	spore germination
EGX84_RS14525	COG0303	'Molybdopterin
EGX84_RS14530	COG0315	cyclic pyranopterin monophosphate synthase activity
EGX84_RS14530	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGX84_RS14545	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGX84_RS14550	COG0243	molybdopterin cofactor binding
EGX84_RS14560	COG0243	molybdopterin cofactor binding
EGX84_RS14565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX84_RS14570	COG2146	nitrite reductase [NAD(P)H] activity
EGX84_RS14570	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX84_RS14580	COG0745	RESPONSE REGULATOR receiver
EGX84_RS14585	COG1116	anion transmembrane transporter activity
EGX84_RS14585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGX84_RS14600	COG0511	ligase activity, forming carbon-carbon bonds
EGX84_RS14615	COG2814	Major facilitator Superfamily
EGX84_RS14625	COG2194	sulfuric ester hydrolase activity
EGX84_RS14670	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGX84_RS14730	COG3566	protein conserved in bacteria
EGX84_RS14745	COG3567	Phage-associated protein, HI1409 family
EGX84_RS14750	COG5410	chromosome segregation
EGX84_RS14945	COG0069	glutamate synthase activity
EGX84_RS14965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGX84_RS14975	COG1454	alcohol dehydrogenase
EGX84_RS14980	COG0824	Thioesterase
EGX84_RS14990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGX84_RS15005	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGX84_RS15010	COG2030	dehydratase
EGX84_RS15020	COG0183	Belongs to the thiolase family
EGX84_RS15030	COG0583	DNA-binding transcription factor activity
EGX84_RS15035	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGX84_RS15045	COG1522	sequence-specific DNA binding
EGX84_RS15050	COG3135	benzoate transporter
EGX84_RS15080	COG0589	response to stress
EGX84_RS15085	COG0488	(ABC) transporter
EGX84_RS15110	COG4773	Receptor
EGX84_RS15155	COG1605	Chorismate mutase
EGX84_RS15175	COG0308	aminopeptidase N
EGX84_RS15195	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EGX84_RS15205	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGX84_RS15210	COG1454	alcohol dehydrogenase
EGX84_RS15230	COG0531	amino acid
EGX84_RS15235	COG4303	Ethanolamine ammonia lyase large subunit
EGX84_RS15240	COG4302	ethanolamine ammonia-lyase activity
EGX84_RS15245	COG0519	Catalyzes the synthesis of GMP from XMP
EGX84_RS15245	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGX84_RS15250	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGX84_RS15280	COG0697	spore germination
EGX84_RS15285	COG1923	regulation of RNA biosynthetic process
EGX84_RS15295	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGX84_RS15300	COG0802	atpase or kinase
EGX84_RS15320	COG1187	pseudouridine synthase activity
EGX84_RS15335	COG0583	DNA-binding transcription factor activity
EGX84_RS15355	COG2814	Major facilitator Superfamily
EGX84_RS15360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGX84_RS15395	COG0729	surface antigen
EGX84_RS15415	COG0174	glutamine synthetase
EGX84_RS15420	COG0745	RESPONSE REGULATOR receiver
EGX84_RS15425	COG2205	protein histidine kinase activity
EGX84_RS15435	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EGX84_RS15440	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EGX84_RS15465	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGX84_RS15470	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGX84_RS15475	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS15505	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGX84_RS15515	COG3658	cytochrome
EGX84_RS15520	COG1215	transferase activity, transferring glycosyl groups
EGX84_RS15525	COG1649	PFAM Uncharacterised BCR, COG1649
EGX84_RS15525	COG0726	polysaccharide deacetylase
EGX84_RS15550	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGX84_RS15555	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGX84_RS15565	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGX84_RS15590	COG0305	Participates in initiation and elongation during chromosome replication
EGX84_RS15595	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGX84_RS15605	COG1305	Transglutaminase-like
EGX84_RS15615	COG2308	Evidence 4 Homologs of previously reported genes of
EGX84_RS15645	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EGX84_RS15650	COG0138	bifunctional purine biosynthesis protein purh
EGX84_RS15655	COG0151	Belongs to the GarS family
EGX84_RS15660	COG1464	Belongs to the NlpA lipoprotein family
EGX84_RS15665	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGX84_RS15670	COG2011	ABC-type metal ion transport system permease component
EGX84_RS15675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX84_RS15685	COG1301	dicarboxylic acid transport
EGX84_RS15700	COG1794	racemase activity, acting on amino acids and derivatives
EGX84_RS15715	COG3008	intermembrane lipid transfer
EGX84_RS15715	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGX84_RS15720	COG2995	paraquat-inducible protein a
EGX84_RS15755	COG2801	Transposase and inactivated derivatives
EGX84_RS15775	COG1051	belongs to the nudix hydrolase family
EGX84_RS15780	COG0477	Major facilitator Superfamily
EGX84_RS15860	COG0515	serine threonine protein kinase
EGX84_RS15860	COG2815	serine threonine protein kinase
EGX84_RS15890	COG1610	YqeY-like protein
EGX84_RS15895	COG4783	chaperone-mediated protein folding
EGX84_RS15920	COG1286	toxin biosynthetic process
EGX84_RS15950	COG0778	Nitroreductase
EGX84_RS15960	COG0513	Belongs to the DEAD box helicase family
EGX84_RS15980	COG2363	Small membrane protein
EGX84_RS16010	COG1234	tRNA 3'-trailer cleavage
EGX84_RS16015	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGX84_RS16025	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGX84_RS16040	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS16045	COG1301	dicarboxylic acid transport
EGX84_RS16055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGX84_RS16060	COG3139	Protein of unknown function (DUF1315)
EGX84_RS16065	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGX84_RS16070	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGX84_RS16080	COG0494	nUDIX hydrolase
EGX84_RS16090	COG0642	Histidine kinase
EGX84_RS16105	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGX84_RS16115	COG1720	tRNA m6t6A37 methyltransferase activity
EGX84_RS16135	COG0826	peptidase U32
EGX84_RS16140	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGX84_RS16150	COG2826	transposase and inactivated derivatives, IS30 family
EGX84_RS16155	COG4598	ABC transporter
EGX84_RS16160	COG4160	amino acid transport
EGX84_RS16165	COG4215	(ABC) transporter
EGX84_RS16180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX84_RS16285	COG2314	TM2 domain
EGX84_RS16345	COG3566	protein conserved in bacteria
EGX84_RS16365	COG3567	Phage-associated protein, HI1409 family
EGX84_RS16370	COG5410	chromosome segregation
EGX84_RS16535	COG0582	viral genome integration into host DNA
EGX84_RS16540	COG1131	(ABC) transporter
EGX84_RS16545	COG0842	Transport permease protein
EGX84_RS16560	COG0772	Belongs to the SEDS family
EGX84_RS16565	COG2951	lytic endotransglycosylase activity
EGX84_RS16590	COG2207	Transcriptional regulator
EGX84_RS16605	COG0052	Belongs to the universal ribosomal protein uS2 family
EGX84_RS16610	COG0024	Methionine aminopeptidase
EGX84_RS16620	COG2223	nitrite transmembrane transporter activity
EGX84_RS16630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX84_RS16635	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGX84_RS16640	COG1960	acyl-CoA dehydrogenase activity
EGX84_RS16655	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EGX84_RS16660	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGX84_RS16665	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGX84_RS16685	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX84_RS16690	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGX84_RS16695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGX84_RS16730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EGX84_RS16740	COG0174	glutamine synthetase
EGX84_RS16755	COG0512	Glutamine amidotransferase of anthranilate synthase
EGX84_RS16760	COG0308	aminopeptidase N
EGX84_RS16790	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EGX84_RS16810	COG0302	gtp cyclohydrolase
EGX84_RS16830	COG3739	integral membrane protein
EGX84_RS16855	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EGX84_RS16860	COG1132	(ABC) transporter
EGX84_RS16865	COG1132	(ABC) transporter
EGX84_RS16880	COG1535	isochorismatase
EGX84_RS16880	COG3433	isochorismatase activity
EGX84_RS16885	COG1021	2,3-dihydroxybenzoate-AMP ligase
EGX84_RS16890	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX84_RS16900	COG4774	siderophore transport
EGX84_RS16905	COG4607	ABC-type enterochelin transport system periplasmic component
EGX84_RS16910	COG4604	ABC transporter, ATP-binding protein
EGX84_RS16915	COG4605	iron ion homeostasis
EGX84_RS16920	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGX84_RS16925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX84_RS16940	COG2964	Protein conserved in bacteria
EGX84_RS16950	COG1741	Belongs to the pirin family
EGX84_RS16975	COG2826	transposase and inactivated derivatives, IS30 family
EGX84_RS16995	COG3659	wide pore channel activity
EGX84_RS17005	COG2826	transposase and inactivated derivatives, IS30 family
EGX84_RS17010	COG1309	transcriptional regulator
EGX84_RS17015	COG1012	belongs to the aldehyde dehydrogenase family
EGX84_RS17020	COG0477	Major facilitator Superfamily
EGX84_RS17035	COG1522	sequence-specific DNA binding
EGX84_RS17040	COG4638	Rieske (2fe-2S)
EGX84_RS17065	COG3961	Belongs to the TPP enzyme family
EGX84_RS17075	COG3961	Belongs to the TPP enzyme family
EGX84_RS17090	COG2879	small protein
EGX84_RS17095	COG1966	Carbon starvation protein
EGX84_RS17115	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EGX84_RS17140	COG1067	ATP-dependent peptidase activity
EGX84_RS17145	COG0583	DNA-binding transcription factor activity
EGX84_RS17170	COG1686	Belongs to the peptidase S11 family
EGX84_RS17175	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGX84_RS17215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGX84_RS17225	COG0573	inorganic phosphate transmembrane transporter activity
EGX84_RS17230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGX84_RS17235	COG1113	amino acid transport
EGX84_RS17240	COG3961	Belongs to the TPP enzyme family
EGX84_RS17245	COG1522	sequence-specific DNA binding
EGX84_RS17255	COG0076	glutamate decarboxylase activity
EGX84_RS17260	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGX84_RS17280	COG1309	transcriptional regulator
EGX84_RS17295	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGX84_RS17330	COG0352	thiamine-phosphate diphosphorylase activity
EGX84_RS17355	COG0612	Peptidase, M16
EGX84_RS17365	COG1823	symporter activity
EGX84_RS17370	COG0583	DNA-binding transcription factor activity
EGX84_RS17375	COG0477	Major facilitator Superfamily
EGX84_RS17400	COG1187	pseudouridine synthase activity
EGX84_RS17415	COG1686	Belongs to the peptidase S11 family
EGX84_RS17420	COG1252	NADH dehydrogenase
EGX84_RS17430	COG0415	Belongs to the DNA photolyase family
EGX84_RS17450	COG1215	transferase activity, transferring glycosyl groups
EGX84_RS17480	COG2070	2-Nitropropane dioxygenase
EGX84_RS17535	COG0556	nucleotide-excision repair
EGX84_RS17555	COG0436	Aminotransferase
EGX84_RS17585	COG4221	oxidoreductase activity
EGX84_RS17595	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGX84_RS17600	COG1381	Involved in DNA repair and RecF pathway recombination
EGX84_RS17610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGX84_RS17625	COG0681	Belongs to the peptidase S26 family
EGX84_RS17640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGX84_RS17660	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGX84_RS17665	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGX84_RS17670	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGX84_RS17680	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGX84_RS17685	COG4208	sulfate ABC transporter
EGX84_RS17690	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGX84_RS17695	COG0583	DNA-binding transcription factor activity
EGX84_RS17715	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EGX84_RS17730	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGX84_RS17740	COG1056	cytidyltransferase-related domain
EGX84_RS17740	COG1051	belongs to the nudix hydrolase family
EGX84_RS17745	COG1024	Enoyl-CoA hydratase
EGX84_RS17765	COG2814	Major facilitator Superfamily
EGX84_RS17770	COG0047	phosphoribosylformylglycinamidine synthase activity
EGX84_RS17770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGX84_RS17790	COG1473	amidohydrolase
EGX84_RS17795	COG0824	Thioesterase
EGX84_RS17815	COG0823	Involved in the tonB-independent uptake of proteins
EGX84_RS17835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGX84_RS17870	COG0628	permease
EGX84_RS17880	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGX84_RS17885	COG0596	Alpha beta hydrolase
EGX84_RS17890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EGX84_RS17890	COG0616	signal peptide processing
EGX84_RS17900	COG0658	competence protein
EGX84_RS17900	COG2333	competence protein COMEC
EGX84_RS17905	COG1136	(ABC) transporter
EGX84_RS17910	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGX84_RS17940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX84_RS17960	COG0463	Glycosyl transferase, family 2
EGX84_RS17990	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGX84_RS17995	COG1280	lysine exporter protein (LysE YggA)
EGX84_RS18005	COG0019	diaminopimelate decarboxylase activity
EGX84_RS18015	COG1113	amino acid transport
EGX84_RS18040	COG3339	Conserved Protein
EGX84_RS18045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EGX84_RS18050	COG0243	molybdopterin cofactor binding
EGX84_RS18055	COG1929	Belongs to the glycerate kinase type-1 family
EGX84_RS18070	COG0778	Nitroreductase
EGX84_RS18105	COG0210	DNA helicase
EGX84_RS18125	COG0697	spore germination
EGX84_RS18135	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
EGX84_RS18145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGX84_RS18275	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGX84_RS18300	COG0741	lytic transglycosylase activity
EGX84_RS18320	COG0584	glycerophosphoryl diester phosphodiesterase
EGX84_RS18325	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGX84_RS18345	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGX84_RS18350	COG1597	lipid kinase activity
EGX84_RS18365	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGX84_RS18370	COG0477	Major facilitator Superfamily
EGX84_RS18420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGX84_RS18425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGX84_RS18450	COG0505	Belongs to the CarA family
EGX84_RS18465	COG1309	transcriptional regulator
EGX84_RS18470	COG0251	oxidation-reduction process
EGX84_RS18480	COG0589	response to stress
EGX84_RS18495	COG2843	Capsule synthesis protein
EGX84_RS18505	COG2015	COG2015, Alkyl sulfatase and related hydrolases
EGX84_RS18530	COG2321	neutral zinc metallopeptidase
EGX84_RS18535	COG2354	Protein conserved in bacteria
EGX84_RS18555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGX84_RS18580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGX84_RS18585	COG1053	succinate dehydrogenase
EGX84_RS18590	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGX84_RS18595	COG2009	succinate dehydrogenase
EGX84_RS18630	COG2921	Belongs to the UPF0250 family
EGX84_RS18635	COG0321	lipoyl(octanoyl) transferase activity
EGX84_RS18650	COG0531	amino acid
EGX84_RS18660	COG1733	regulation of RNA biosynthetic process
EGX84_RS18665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGX84_RS18670	COG1648	precorrin-2 dehydrogenase activity
EGX84_RS18670	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGX84_RS18685	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EGX84_RS18715	COG0671	phosphoesterase, PA-phosphatase related
EGX84_RS18720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGX84_RS18730	COG1538	Outer membrane efflux protein
EGX84_RS18735	COG0393	Putative heavy-metal-binding
EGX84_RS18740	COG0393	Putative heavy-metal-binding
EGX84_RS18750	COG1028	Short-chain dehydrogenase reductase Sdr
EGX84_RS18760	COG0525	valine-tRNA ligase activity
EGX84_RS18780	COG0583	DNA-binding transcription factor activity
EGX84_RS18800	COG0642	Histidine kinase
EGX84_RS18805	COG0745	RESPONSE REGULATOR receiver
EGX84_RS18810	COG2194	sulfuric ester hydrolase activity
EGX84_RS18830	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGX84_RS18845	COG2315	Protein conserved in bacteria
EGX84_RS18850	COG0142	geranyltranstransferase activity
EGX84_RS18855	COG2828	Protein conserved in bacteria
EGX84_RS18860	COG1113	amino acid transport
EGX84_RS18880	COG2207	Transcriptional regulator
EGX84_RS18905	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGX84_RS18925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGX84_RS18935	COG1530	ribonuclease E activity
EGX84_RS18940	COG0424	maF-like protein
EGX84_RS18945	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EGX84_RS18950	COG1792	Involved in formation and maintenance of cell shape
EGX84_RS18955	COG1077	Cell shape determining protein MreB Mrl
EGX84_RS18960	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGX84_RS18970	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGX84_RS18990	COG3590	peptidase
EGX84_RS18995	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EGX84_RS19000	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGX84_RS19005	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGX84_RS19010	COG1115	amino acid carrier protein
EGX84_RS19035	COG1289	transmembrane transporter activity
EGX84_RS19045	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGX84_RS19085	COG1376	ErfK ybiS ycfS ynhG family protein
EGX84_RS19090	COG2832	Protein of unknown function (DUF454)
EGX84_RS19100	COG5510	response to toxic substance
EGX84_RS19120	COG0840	transmembrane signaling receptor activity
EGX84_RS19160	COG3422	double-strand break repair
EGX84_RS19165	COG2824	Alkylphosphonate utilization operon protein PhnA
EGX84_RS19170	COG3189	MarR family transcriptional regulator
EGX84_RS19180	COG0354	folic acid binding
EGX84_RS19185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGX84_RS19195	COG0679	Auxin Efflux Carrier
EGX84_RS19200	COG1902	pentaerythritol trinitrate reductase activity
EGX84_RS19205	COG4772	TonB-dependent receptor
EGX84_RS19210	COG2094	Belongs to the DNA glycosylase MPG family
EGX84_RS19235	COG1217	gtp-binding protein TYPA
EGX84_RS19240	COG2233	PERMEase
EGX84_RS19250	COG0833	amino acid
EGX84_RS19255	COG1690	Belongs to the RtcB family
EGX84_RS19260	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGX84_RS19260	COG2885	chlorophyll binding
EGX84_RS19270	COG0183	Belongs to the thiolase family
EGX84_RS19290	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGX84_RS19310	COG2207	Transcriptional regulator
EGX84_RS19315	COG0183	Belongs to the thiolase family
EGX84_RS19345	COG1272	protein, Hemolysin III
EGX84_RS19350	COG0477	Major facilitator Superfamily
EGX84_RS19365	COG0450	alkyl hydroperoxide reductase
EGX84_RS19385	COG0285	dihydrofolate synthase activity
EGX84_RS19435	COG2096	Adenosyltransferase