locus-tag	class	description
LHJ63_RS00010	COG0592	DNA-directed DNA polymerase activity
LHJ63_RS00020	COG0187	DNA topoisomerase II activity
LHJ63_RS00030	COG0586	Pfam SNARE associated Golgi protein
LHJ63_RS00035	COG0488	(ABC) transporter
LHJ63_RS00060	COG0596	Alpha beta hydrolase
LHJ63_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LHJ63_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LHJ63_RS00110	COG0733	neurotransmitter:sodium symporter activity
LHJ63_RS00150	COG2233	PERMEase
LHJ63_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHJ63_RS00200	COG2814	Major facilitator Superfamily
LHJ63_RS00205	COG0656	L-ascorbic acid biosynthetic process
LHJ63_RS00210	COG0583	DNA-binding transcription factor activity
LHJ63_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LHJ63_RS00230	COG1064	alcohol dehydrogenase
LHJ63_RS00235	COG2818	Glycosylase
LHJ63_RS00250	COG1194	a g-specific adenine glycosylase
LHJ63_RS00270	COG2983	Belongs to the UPF0260 family
LHJ63_RS00275	COG2133	pyrroloquinoline quinone binding
LHJ63_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LHJ63_RS00285	COG2116	formate transmembrane transporter activity
LHJ63_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHJ63_RS00310	COG1335	isochorismatase
LHJ63_RS00315	COG0385	Bile acid
LHJ63_RS00320	COG0534	Mate efflux family protein
LHJ63_RS00325	COG1683	Conserved Protein
LHJ63_RS00345	COG0625	glutathione transferase activity
LHJ63_RS00355	COG1113	amino acid transport
LHJ63_RS00365	COG0523	cobalamin synthesis protein
LHJ63_RS00375	COG2188	Transcriptional regulator
LHJ63_RS00405	COG0010	Belongs to the arginase family
LHJ63_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LHJ63_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LHJ63_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LHJ63_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LHJ63_RS00540	COG0534	Mate efflux family protein
LHJ63_RS00545	COG0436	Aminotransferase
LHJ63_RS00550	COG2733	membrane
LHJ63_RS00565	COG2918	glutathione biosynthetic process
LHJ63_RS00580	COG0791	NLP P60 protein
LHJ63_RS00580	COG1388	LysM domain
LHJ63_RS00595	COG3150	esterase
LHJ63_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LHJ63_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LHJ63_RS00630	COG2233	PERMEase
LHJ63_RS00635	COG2351	hydroxyisourate hydrolase activity
LHJ63_RS00670	COG3706	GGDEF domain
LHJ63_RS00685	COG1393	Belongs to the ArsC family
LHJ63_RS00690	COG0708	Exodeoxyribonuclease III
LHJ63_RS00710	COG0189	ligase activity
LHJ63_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LHJ63_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LHJ63_RS00755	COG4942	peptidase
LHJ63_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
LHJ63_RS00775	COG2119	membrane
LHJ63_RS00780	COG4774	siderophore transport
LHJ63_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LHJ63_RS00785	COG0426	domain, Protein
LHJ63_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LHJ63_RS00830	COG1902	pentaerythritol trinitrate reductase activity
LHJ63_RS00835	COG1519	Transferase
LHJ63_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LHJ63_RS00845	COG0668	transmembrane transport
LHJ63_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LHJ63_RS00860	COG1335	isochorismatase
LHJ63_RS00865	COG1522	sequence-specific DNA binding
LHJ63_RS00870	COG3328	transposase activity
LHJ63_RS00895	COG0784	Response regulator, receiver
LHJ63_RS00895	COG2198	Histidine kinase
LHJ63_RS00895	COG2205	protein histidine kinase activity
LHJ63_RS00900	COG3162	membrane
LHJ63_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHJ63_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LHJ63_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LHJ63_RS00940	COG1309	transcriptional regulator
LHJ63_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LHJ63_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
LHJ63_RS00960	COG0351	phosphomethylpyrimidine kinase
LHJ63_RS00970	COG2814	Major facilitator Superfamily
LHJ63_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LHJ63_RS00995	COG1113	amino acid transport
LHJ63_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LHJ63_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS01020	COG1335	isochorismatase
LHJ63_RS01050	COG2814	Major facilitator Superfamily
LHJ63_RS01055	COG0583	DNA-binding transcription factor activity
LHJ63_RS01075	COG0667	Aldo Keto reductase
LHJ63_RS01110	COG1733	regulation of RNA biosynthetic process
LHJ63_RS01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
LHJ63_RS01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LHJ63_RS01195	COG2329	Antibiotic biosynthesis monooxygenase
LHJ63_RS01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LHJ63_RS01255	COG0427	acetyl-CoA hydrolase
LHJ63_RS01280	COG0659	secondary active sulfate transmembrane transporter activity
LHJ63_RS01285	COG4221	oxidoreductase activity
LHJ63_RS01290	COG2873	o-acetylhomoserine
LHJ63_RS01295	COG0488	(ABC) transporter
LHJ63_RS01385	COG0833	amino acid
LHJ63_RS01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LHJ63_RS01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LHJ63_RS01450	COG2226	methyltransferase
LHJ63_RS01500	COG0067	glutamate synthase
LHJ63_RS01500	COG0069	glutamate synthase activity
LHJ63_RS01500	COG0070	glutamate synthase
LHJ63_RS01505	COG0493	'glutamate synthase
LHJ63_RS01515	COG1704	LemA family
LHJ63_RS01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LHJ63_RS01540	COG3307	-O-antigen
LHJ63_RS01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LHJ63_RS01575	COG0194	GDP metabolic process
LHJ63_RS01625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LHJ63_RS01645	COG5380	lipid catabolic process
LHJ63_RS01650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LHJ63_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LHJ63_RS01680	COG0277	FAD linked oxidase domain protein
LHJ63_RS01690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LHJ63_RS01695	COG2249	NAD(P)H dehydrogenase (quinone) activity
LHJ63_RS01710	COG1289	transmembrane transporter activity
LHJ63_RS01720	COG0628	permease
LHJ63_RS01725	COG1192	Involved in chromosome partitioning
LHJ63_RS01755	COG0833	amino acid
LHJ63_RS01760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LHJ63_RS01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LHJ63_RS01775	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS01815	COG0583	DNA-binding transcription factor activity
LHJ63_RS01860	COG0517	IMP dehydrogenase activity
LHJ63_RS01865	COG1983	PspC domain protein
LHJ63_RS01875	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS01890	COG0408	coproporphyrinogen oxidase activity
LHJ63_RS01910	COG0513	Belongs to the DEAD box helicase family
LHJ63_RS01920	COG1127	ABC transporter
LHJ63_RS01925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LHJ63_RS01935	COG2854	intermembrane phospholipid transfer
LHJ63_RS01945	COG0598	Magnesium transport protein CorA
LHJ63_RS01955	COG0494	nUDIX hydrolase
LHJ63_RS01960	COG1040	competence protein
LHJ63_RS01965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LHJ63_RS01985	COG1946	Acyl-CoA thioesterase
LHJ63_RS01990	COG1301	dicarboxylic acid transport
LHJ63_RS02005	COG1959	2 iron, 2 sulfur cluster binding
LHJ63_RS02010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LHJ63_RS02010	COG1017	nitric oxide dioxygenase activity
LHJ63_RS02015	COG0433	COG0433 Predicted ATPase
LHJ63_RS02020	COG0626	cystathionine gamma-synthase activity
LHJ63_RS02175	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LHJ63_RS02210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LHJ63_RS02215	COG0339	signal peptide processing
LHJ63_RS02220	COG0557	exoribonuclease II activity
LHJ63_RS02265	COG0179	Fumarylacetoacetate (FAA) hydrolase
LHJ63_RS02270	COG2169	Transcriptional regulator
LHJ63_RS02275	COG0697	spore germination
LHJ63_RS02280	COG1295	ribonuclease BN
LHJ63_RS02315	COG1702	phosphate starvation-inducible protein PhoH
LHJ63_RS02325	COG1196	nuclear chromosome segregation
LHJ63_RS02325	COG0741	lytic transglycosylase activity
LHJ63_RS02325	COG0739	heme binding
LHJ63_RS02355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LHJ63_RS02360	COG1183	phosphatidylcholine synthase activity
LHJ63_RS02405	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS02410	COG1309	transcriptional regulator
LHJ63_RS02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LHJ63_RS02430	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS02450	COG2969	positive regulation of protein catabolic process
LHJ63_RS02460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LHJ63_RS02475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LHJ63_RS02480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LHJ63_RS02500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LHJ63_RS02510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHJ63_RS02515	COG1408	metallophosphoesterase
LHJ63_RS02525	COG2199	diguanylate cyclase activity
LHJ63_RS02585	COG1607	acyl-coa hydrolase
LHJ63_RS02615	COG2350	Protein conserved in bacteria
LHJ63_RS02625	COG0613	PHP domain protein
LHJ63_RS02630	COG3781	membrane
LHJ63_RS02640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LHJ63_RS02645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LHJ63_RS02655	COG1862	Preprotein translocase
LHJ63_RS02685	COG2205	protein histidine kinase activity
LHJ63_RS02690	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LHJ63_RS02710	COG0726	polysaccharide deacetylase
LHJ63_RS02715	COG0463	Glycosyl transferase, family 2
LHJ63_RS02720	COG0438	transferase activity, transferring glycosyl groups
LHJ63_RS02785	COG0625	glutathione transferase activity
LHJ63_RS02790	COG0583	DNA-binding transcription factor activity
LHJ63_RS02795	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS02800	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS02810	COG2205	protein histidine kinase activity
LHJ63_RS02815	COG0745	RESPONSE REGULATOR receiver
LHJ63_RS02820	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LHJ63_RS02840	COG2096	Adenosyltransferase
LHJ63_RS02890	COG0285	dihydrofolate synthase activity
LHJ63_RS02910	COG0450	alkyl hydroperoxide reductase
LHJ63_RS02925	COG0477	Major facilitator Superfamily
LHJ63_RS02930	COG1272	protein, Hemolysin III
LHJ63_RS02960	COG0183	Belongs to the thiolase family
LHJ63_RS02965	COG2207	Transcriptional regulator
LHJ63_RS02985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LHJ63_RS03005	COG0183	Belongs to the thiolase family
LHJ63_RS03015	COG2885	chlorophyll binding
LHJ63_RS03015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LHJ63_RS03025	COG1690	Belongs to the RtcB family
LHJ63_RS03030	COG0833	amino acid
LHJ63_RS03040	COG2233	PERMEase
LHJ63_RS03045	COG1217	gtp-binding protein TYPA
LHJ63_RS03070	COG2094	Belongs to the DNA glycosylase MPG family
LHJ63_RS03090	COG1902	pentaerythritol trinitrate reductase activity
LHJ63_RS03105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LHJ63_RS03110	COG0354	folic acid binding
LHJ63_RS03120	COG3189	MarR family transcriptional regulator
LHJ63_RS03125	COG2824	Alkylphosphonate utilization operon protein PhnA
LHJ63_RS03130	COG3422	double-strand break repair
LHJ63_RS03170	COG0840	transmembrane signaling receptor activity
LHJ63_RS03190	COG5510	response to toxic substance
LHJ63_RS03200	COG2832	Protein of unknown function (DUF454)
LHJ63_RS03205	COG1376	ErfK ybiS ycfS ynhG family protein
LHJ63_RS03245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LHJ63_RS03255	COG1289	transmembrane transporter activity
LHJ63_RS03260	COG2814	Major facilitator Superfamily
LHJ63_RS03280	COG1115	amino acid carrier protein
LHJ63_RS03285	COG1752	Esterase of the alpha-beta hydrolase superfamily
LHJ63_RS03290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LHJ63_RS03295	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LHJ63_RS03335	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHJ63_RS03345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LHJ63_RS03350	COG1077	Cell shape determining protein MreB Mrl
LHJ63_RS03355	COG1792	Involved in formation and maintenance of cell shape
LHJ63_RS03360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LHJ63_RS03365	COG0424	maF-like protein
LHJ63_RS03370	COG1530	ribonuclease E activity
LHJ63_RS03380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LHJ63_RS03390	COG0560	Phosphoserine phosphatase
LHJ63_RS03400	COG2249	NAD(P)H dehydrogenase (quinone) activity
LHJ63_RS03425	COG2207	Transcriptional regulator
LHJ63_RS03445	COG1113	amino acid transport
LHJ63_RS03450	COG2828	Protein conserved in bacteria
LHJ63_RS03455	COG0142	geranyltranstransferase activity
LHJ63_RS03460	COG2315	Protein conserved in bacteria
LHJ63_RS03475	COG1752	Esterase of the alpha-beta hydrolase superfamily
LHJ63_RS03495	COG2194	sulfuric ester hydrolase activity
LHJ63_RS03500	COG0745	RESPONSE REGULATOR receiver
LHJ63_RS03505	COG0642	Histidine kinase
LHJ63_RS03515	COG0004	ammonium transporteR
LHJ63_RS03520	COG0583	DNA-binding transcription factor activity
LHJ63_RS03540	COG0525	valine-tRNA ligase activity
LHJ63_RS03550	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS03560	COG0393	Putative heavy-metal-binding
LHJ63_RS03565	COG0393	Putative heavy-metal-binding
LHJ63_RS03570	COG1538	Outer membrane efflux protein
LHJ63_RS03580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHJ63_RS03585	COG0671	phosphoesterase, PA-phosphatase related
LHJ63_RS03615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LHJ63_RS03630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LHJ63_RS03630	COG1648	precorrin-2 dehydrogenase activity
LHJ63_RS03635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LHJ63_RS03640	COG1733	regulation of RNA biosynthetic process
LHJ63_RS03650	COG0531	amino acid
LHJ63_RS03665	COG0321	lipoyl(octanoyl) transferase activity
LHJ63_RS03670	COG2921	Belongs to the UPF0250 family
LHJ63_RS03710	COG2009	succinate dehydrogenase
LHJ63_RS03715	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LHJ63_RS03720	COG1053	succinate dehydrogenase
LHJ63_RS03725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LHJ63_RS03750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LHJ63_RS03770	COG2354	Protein conserved in bacteria
LHJ63_RS03775	COG2321	neutral zinc metallopeptidase
LHJ63_RS03795	COG2843	Capsule synthesis protein
LHJ63_RS03810	COG0589	response to stress
LHJ63_RS03830	COG0505	Belongs to the CarA family
LHJ63_RS03855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LHJ63_RS03860	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LHJ63_RS03910	COG0477	Major facilitator Superfamily
LHJ63_RS03915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LHJ63_RS03930	COG1597	lipid kinase activity
LHJ63_RS03935	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LHJ63_RS03965	COG0584	glycerophosphoryl diester phosphodiesterase
LHJ63_RS03985	COG0741	lytic transglycosylase activity
LHJ63_RS04005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LHJ63_RS04020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LHJ63_RS04050	COG0778	Nitroreductase
LHJ63_RS04065	COG1929	Belongs to the glycerate kinase type-1 family
LHJ63_RS04070	COG0243	molybdopterin cofactor binding
LHJ63_RS04075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LHJ63_RS04080	COG3339	Conserved Protein
LHJ63_RS04090	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LHJ63_RS04105	COG1113	amino acid transport
LHJ63_RS04115	COG0019	diaminopimelate decarboxylase activity
LHJ63_RS04125	COG1280	lysine exporter protein (LysE YggA)
LHJ63_RS04130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LHJ63_RS04160	COG0463	Glycosyl transferase, family 2
LHJ63_RS04180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHJ63_RS04215	COG4591	ABC-type transport system involved in lipoprotein release permease component
LHJ63_RS04220	COG1136	(ABC) transporter
LHJ63_RS04225	COG2333	competence protein COMEC
LHJ63_RS04225	COG0658	competence protein
LHJ63_RS04235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LHJ63_RS04235	COG0616	signal peptide processing
LHJ63_RS04240	COG0596	Alpha beta hydrolase
LHJ63_RS04245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LHJ63_RS04255	COG0628	permease
LHJ63_RS04290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHJ63_RS04310	COG0823	Involved in the tonB-independent uptake of proteins
LHJ63_RS04330	COG0824	Thioesterase
LHJ63_RS04335	COG1473	amidohydrolase
LHJ63_RS04355	COG0047	phosphoribosylformylglycinamidine synthase activity
LHJ63_RS04355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LHJ63_RS04360	COG2814	Major facilitator Superfamily
LHJ63_RS04370	COG1024	Enoyl-CoA hydratase
LHJ63_RS04375	COG1051	belongs to the nudix hydrolase family
LHJ63_RS04375	COG1056	cytidyltransferase-related domain
LHJ63_RS04385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LHJ63_RS04400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LHJ63_RS04415	COG4625	pathogenesis
LHJ63_RS04420	COG0583	DNA-binding transcription factor activity
LHJ63_RS04425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LHJ63_RS04430	COG4208	sulfate ABC transporter
LHJ63_RS04435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LHJ63_RS04445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LHJ63_RS04450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LHJ63_RS04455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LHJ63_RS04475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHJ63_RS04490	COG0681	Belongs to the peptidase S26 family
LHJ63_RS04505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LHJ63_RS04515	COG1381	Involved in DNA repair and RecF pathway recombination
LHJ63_RS04520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LHJ63_RS04530	COG4221	oxidoreductase activity
LHJ63_RS04560	COG0436	Aminotransferase
LHJ63_RS04580	COG0556	nucleotide-excision repair
LHJ63_RS04635	COG2070	2-Nitropropane dioxygenase
LHJ63_RS04665	COG1215	transferase activity, transferring glycosyl groups
LHJ63_RS04680	COG0415	Belongs to the DNA photolyase family
LHJ63_RS04690	COG1252	NADH dehydrogenase
LHJ63_RS04695	COG1686	Belongs to the peptidase S11 family
LHJ63_RS04710	COG1187	pseudouridine synthase activity
LHJ63_RS04735	COG0477	Major facilitator Superfamily
LHJ63_RS04740	COG0583	DNA-binding transcription factor activity
LHJ63_RS04745	COG1823	symporter activity
LHJ63_RS04755	COG0612	Peptidase, M16
LHJ63_RS04780	COG0352	thiamine-phosphate diphosphorylase activity
LHJ63_RS04815	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LHJ63_RS04830	COG1309	transcriptional regulator
LHJ63_RS04840	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LHJ63_RS04845	COG0076	glutamate decarboxylase activity
LHJ63_RS04855	COG1522	sequence-specific DNA binding
LHJ63_RS04860	COG3961	Belongs to the TPP enzyme family
LHJ63_RS04865	COG1113	amino acid transport
LHJ63_RS04870	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LHJ63_RS04875	COG0573	inorganic phosphate transmembrane transporter activity
LHJ63_RS04885	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LHJ63_RS04890	COG0616	signal peptide processing
LHJ63_RS04900	COG3328	transposase activity
LHJ63_RS04930	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LHJ63_RS04935	COG1686	Belongs to the peptidase S11 family
LHJ63_RS04960	COG0583	DNA-binding transcription factor activity
LHJ63_RS04965	COG1067	ATP-dependent peptidase activity
LHJ63_RS05010	COG1966	Carbon starvation protein
LHJ63_RS05015	COG2879	small protein
LHJ63_RS05050	COG2508	Transcriptional regulator
LHJ63_RS05050	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
LHJ63_RS05070	COG1113	amino acid transport
LHJ63_RS05075	COG0583	DNA-binding transcription factor activity
LHJ63_RS05080	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LHJ63_RS05085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LHJ63_RS05095	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS05105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LHJ63_RS05110	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LHJ63_RS05110	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LHJ63_RS05145	COG2814	Major facilitator Superfamily
LHJ63_RS05150	COG4948	Mandelate Racemase Muconate Lactonizing
LHJ63_RS05160	COG1309	transcriptional regulator
LHJ63_RS05180	COG1741	Belongs to the pirin family
LHJ63_RS05190	COG2964	Protein conserved in bacteria
LHJ63_RS05205	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LHJ63_RS05210	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHJ63_RS05215	COG4605	iron ion homeostasis
LHJ63_RS05220	COG4604	ABC transporter, ATP-binding protein
LHJ63_RS05225	COG4607	ABC-type enterochelin transport system periplasmic component
LHJ63_RS05230	COG4774	siderophore transport
LHJ63_RS05240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LHJ63_RS05245	COG1021	2,3-dihydroxybenzoate-AMP ligase
LHJ63_RS05250	COG1535	isochorismatase
LHJ63_RS05250	COG3433	isochorismatase activity
LHJ63_RS05265	COG1132	(ABC) transporter
LHJ63_RS05270	COG1132	(ABC) transporter
LHJ63_RS05275	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LHJ63_RS05285	COG1169	isochorismate synthase
LHJ63_RS05300	COG3739	integral membrane protein
LHJ63_RS05325	COG0302	gtp cyclohydrolase
LHJ63_RS05335	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LHJ63_RS05365	COG0308	aminopeptidase N
LHJ63_RS05370	COG0512	Glutamine amidotransferase of anthranilate synthase
LHJ63_RS05550	COG5410	chromosome segregation
LHJ63_RS05555	COG3567	Phage-associated protein, HI1409 family
LHJ63_RS05575	COG3566	protein conserved in bacteria
LHJ63_RS05685	COG0582	viral genome integration into host DNA
LHJ63_RS05700	COG0174	glutamine synthetase
LHJ63_RS05710	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LHJ63_RS05745	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LHJ63_RS05750	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LHJ63_RS05755	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LHJ63_RS05775	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LHJ63_RS05780	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LHJ63_RS05785	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LHJ63_RS05800	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS05805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LHJ63_RS05810	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LHJ63_RS05820	COG2223	nitrite transmembrane transporter activity
LHJ63_RS05830	COG0024	Methionine aminopeptidase
LHJ63_RS05835	COG0052	Belongs to the universal ribosomal protein uS2 family
LHJ63_RS05850	COG2207	Transcriptional regulator
LHJ63_RS05875	COG2951	lytic endotransglycosylase activity
LHJ63_RS05880	COG0772	Belongs to the SEDS family
LHJ63_RS05895	COG0842	Transport permease protein
LHJ63_RS05900	COG1131	(ABC) transporter
LHJ63_RS05955	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHJ63_RS05970	COG4215	(ABC) transporter
LHJ63_RS05975	COG4160	amino acid transport
LHJ63_RS05980	COG4598	ABC transporter
LHJ63_RS05990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LHJ63_RS05995	COG0826	peptidase U32
LHJ63_RS06000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LHJ63_RS06015	COG1720	tRNA m6t6A37 methyltransferase activity
LHJ63_RS06025	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LHJ63_RS06040	COG0642	Histidine kinase
LHJ63_RS06050	COG0494	nUDIX hydrolase
LHJ63_RS06060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LHJ63_RS06065	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LHJ63_RS06070	COG3139	Protein of unknown function (DUF1315)
LHJ63_RS06075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LHJ63_RS06080	COG1301	dicarboxylic acid transport
LHJ63_RS06085	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS06090	COG2819	hydrolase of the alpha beta superfamily
LHJ63_RS06100	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LHJ63_RS06110	COG2195	Cleaves the N-terminal amino acid of tripeptides
LHJ63_RS06115	COG1234	tRNA 3'-trailer cleavage
LHJ63_RS06145	COG2363	Small membrane protein
LHJ63_RS06170	COG0513	Belongs to the DEAD box helicase family
LHJ63_RS06180	COG0778	Nitroreductase
LHJ63_RS06210	COG1286	toxin biosynthetic process
LHJ63_RS06235	COG4783	chaperone-mediated protein folding
LHJ63_RS06240	COG1610	YqeY-like protein
LHJ63_RS06340	COG3111	PFAM Bacterial OB fold (BOF) protein
LHJ63_RS06365	COG3243	poly(R)-hydroxyalkanoic acid synthase
LHJ63_RS06370	COG0786	glutamate:sodium symporter activity
LHJ63_RS06380	COG2186	Transcriptional regulator
LHJ63_RS06430	COG0477	Major facilitator Superfamily
LHJ63_RS06460	COG2985	domain, Protein
LHJ63_RS06470	COG2995	paraquat-inducible protein a
LHJ63_RS06475	COG3008	intermembrane lipid transfer
LHJ63_RS06475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LHJ63_RS06510	COG0488	(ABC) transporter
LHJ63_RS06515	COG3173	Aminoglycoside phosphotransferase
LHJ63_RS06525	COG2433	Pfam Transposase IS66
LHJ63_RS06565	COG1301	dicarboxylic acid transport
LHJ63_RS06575	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LHJ63_RS06580	COG2011	ABC-type metal ion transport system permease component
LHJ63_RS06585	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LHJ63_RS06590	COG1464	Belongs to the NlpA lipoprotein family
LHJ63_RS06595	COG0151	Belongs to the GarS family
LHJ63_RS06600	COG0138	bifunctional purine biosynthesis protein purh
LHJ63_RS06605	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LHJ63_RS06635	COG2308	Evidence 4 Homologs of previously reported genes of
LHJ63_RS06645	COG1305	Transglutaminase-like
LHJ63_RS06655	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LHJ63_RS06660	COG0305	Participates in initiation and elongation during chromosome replication
LHJ63_RS06685	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LHJ63_RS06695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LHJ63_RS06700	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LHJ63_RS06725	COG0726	polysaccharide deacetylase
LHJ63_RS06725	COG1649	PFAM Uncharacterised BCR, COG1649
LHJ63_RS06730	COG1215	transferase activity, transferring glycosyl groups
LHJ63_RS06735	COG3658	cytochrome
LHJ63_RS06745	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHJ63_RS06760	COG0583	DNA-binding transcription factor activity
LHJ63_RS06780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LHJ63_RS06785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LHJ63_RS06800	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS06805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LHJ63_RS06810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LHJ63_RS06835	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LHJ63_RS06840	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LHJ63_RS06850	COG2205	protein histidine kinase activity
LHJ63_RS06855	COG0745	RESPONSE REGULATOR receiver
LHJ63_RS06860	COG0174	glutamine synthetase
LHJ63_RS06880	COG0729	surface antigen
LHJ63_RS06905	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LHJ63_RS06910	COG2814	Major facilitator Superfamily
LHJ63_RS06925	COG0583	DNA-binding transcription factor activity
LHJ63_RS06940	COG1187	pseudouridine synthase activity
LHJ63_RS06960	COG0802	atpase or kinase
LHJ63_RS06965	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LHJ63_RS06975	COG1923	regulation of RNA biosynthetic process
LHJ63_RS06980	COG0697	spore germination
LHJ63_RS06995	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LHJ63_RS07005	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LHJ63_RS07010	COG0519	Catalyzes the synthesis of GMP from XMP
LHJ63_RS07010	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LHJ63_RS07015	COG4302	ethanolamine ammonia-lyase activity
LHJ63_RS07020	COG4303	Ethanolamine ammonia lyase large subunit
LHJ63_RS07025	COG0531	amino acid
LHJ63_RS07045	COG1454	alcohol dehydrogenase
LHJ63_RS07050	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LHJ63_RS07060	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LHJ63_RS07080	COG0308	aminopeptidase N
LHJ63_RS07110	COG1605	Chorismate mutase
LHJ63_RS07130	COG1309	transcriptional regulator
LHJ63_RS07140	COG0668	transmembrane transport
LHJ63_RS07175	COG4773	Receptor
LHJ63_RS07195	COG0488	(ABC) transporter
LHJ63_RS07200	COG0589	response to stress
LHJ63_RS07225	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LHJ63_RS07235	COG3135	benzoate transporter
LHJ63_RS07240	COG1522	sequence-specific DNA binding
LHJ63_RS07250	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LHJ63_RS07255	COG0583	DNA-binding transcription factor activity
LHJ63_RS07265	COG0183	Belongs to the thiolase family
LHJ63_RS07275	COG2030	dehydratase
LHJ63_RS07280	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LHJ63_RS07295	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LHJ63_RS07305	COG0824	Thioesterase
LHJ63_RS07310	COG1454	alcohol dehydrogenase
LHJ63_RS07320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LHJ63_RS07340	COG0069	glutamate synthase activity
LHJ63_RS07545	COG5410	chromosome segregation
LHJ63_RS07670	COG0739	heme binding
LHJ63_RS07730	COG2814	Major facilitator Superfamily
LHJ63_RS07745	COG0511	ligase activity, forming carbon-carbon bonds
LHJ63_RS07765	COG1116	anion transmembrane transporter activity
LHJ63_RS07765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LHJ63_RS07770	COG0745	RESPONSE REGULATOR receiver
LHJ63_RS07780	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LHJ63_RS07780	COG2146	nitrite reductase [NAD(P)H] activity
LHJ63_RS07785	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LHJ63_RS07790	COG0243	molybdopterin cofactor binding
LHJ63_RS07800	COG0243	molybdopterin cofactor binding
LHJ63_RS07805	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LHJ63_RS07820	COG0315	cyclic pyranopterin monophosphate synthase activity
LHJ63_RS07820	COG0521	Mo-molybdopterin cofactor biosynthetic process
LHJ63_RS07825	COG0303	'Molybdopterin
LHJ63_RS07835	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LHJ63_RS07840	COG0697	spore germination
LHJ63_RS07860	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LHJ63_RS07865	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LHJ63_RS07920	COG2204	response regulator
LHJ63_RS07925	COG3852	Histidine kinase
LHJ63_RS07945	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LHJ63_RS07950	COG0575	Belongs to the CDS family
LHJ63_RS07985	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LHJ63_RS08000	COG2137	regulation of response to DNA damage stimulus
LHJ63_RS08010	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LHJ63_RS08015	COG1011	Hydrolase
LHJ63_RS08040	COG1522	sequence-specific DNA binding
LHJ63_RS08050	COG1113	amino acid transport
LHJ63_RS08070	COG0659	secondary active sulfate transmembrane transporter activity
LHJ63_RS08075	COG2135	peptidase activity
LHJ63_RS08090	COG5001	Diguanylate cyclase
LHJ63_RS08090	COG3300	MHYT domain
LHJ63_RS08110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LHJ63_RS08110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LHJ63_RS08110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LHJ63_RS08115	COG1105	Belongs to the carbohydrate kinase PfkB family
LHJ63_RS08120	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LHJ63_RS08120	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LHJ63_RS08150	COG0024	Methionine aminopeptidase
LHJ63_RS08155	COG0583	DNA-binding transcription factor activity
LHJ63_RS08165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LHJ63_RS08170	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LHJ63_RS08175	COG0517	IMP dehydrogenase activity
LHJ63_RS08175	COG0516	GMP reductase activity
LHJ63_RS08200	COG0552	protein localization to endoplasmic reticulum
LHJ63_RS08210	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LHJ63_RS08225	COG4890	Cyd operon protein YbgT
LHJ63_RS08230	COG1294	oxidase, subunit
LHJ63_RS08245	COG1585	Membrane protein implicated in regulation of membrane protease activity
LHJ63_RS08255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LHJ63_RS08260	COG4774	siderophore transport
LHJ63_RS08275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LHJ63_RS08280	COG0569	domain protein
LHJ63_RS08285	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LHJ63_RS08315	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LHJ63_RS08320	COG0542	response to heat
LHJ63_RS08345	COG0446	pyridine nucleotide-disulphide oxidoreductase
LHJ63_RS08345	COG1902	pentaerythritol trinitrate reductase activity
LHJ63_RS08390	COG2323	membrane
LHJ63_RS08395	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LHJ63_RS08405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LHJ63_RS08410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LHJ63_RS08415	COG0183	Belongs to the thiolase family
LHJ63_RS08420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LHJ63_RS08425	COG0596	Alpha beta hydrolase
LHJ63_RS08430	COG2271	Major facilitator Superfamily
LHJ63_RS08435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LHJ63_RS08440	COG3485	protocatechuate 3,4-dioxygenase
LHJ63_RS08445	COG3485	protocatechuate 3,4-dioxygenase
LHJ63_RS08450	COG0710	3-dehydroquinate dehydratase activity
LHJ63_RS08455	COG3420	alginic acid biosynthetic process
LHJ63_RS08460	COG3659	wide pore channel activity
LHJ63_RS08465	COG4993	Dehydrogenase
LHJ63_RS08475	COG2391	methyltransferase activity
LHJ63_RS08490	COG1414	Transcriptional regulator
LHJ63_RS08495	COG0583	DNA-binding transcription factor activity
LHJ63_RS08500	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS08525	COG2814	Major facilitator Superfamily
LHJ63_RS08535	COG0154	amidase activity
LHJ63_RS08555	COG4638	Rieske (2fe-2S)
LHJ63_RS08565	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS08575	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LHJ63_RS08585	COG3733	amine oxidase
LHJ63_RS08595	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS08605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LHJ63_RS08610	COG0183	Belongs to the thiolase family
LHJ63_RS08615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LHJ63_RS08620	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LHJ63_RS08630	COG4829	muconolactone delta-isomerase
LHJ63_RS08635	COG4948	Mandelate Racemase Muconate Lactonizing
LHJ63_RS08640	COG0583	DNA-binding transcription factor activity
LHJ63_RS08650	COG2186	Transcriptional regulator
LHJ63_RS08670	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS08690	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS08695	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS08700	COG3829	transcription factor binding
LHJ63_RS08710	COG3162	membrane
LHJ63_RS08725	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS08740	COG0753	catalase activity
LHJ63_RS08760	COG1846	Transcriptional regulator
LHJ63_RS08765	COG0446	pyridine nucleotide-disulphide oxidoreductase
LHJ63_RS08765	COG1902	pentaerythritol trinitrate reductase activity
LHJ63_RS08775	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LHJ63_RS08805	COG1309	transcriptional regulator
LHJ63_RS08815	COG1335	isochorismatase
LHJ63_RS08820	COG0583	DNA-binding transcription factor activity
LHJ63_RS08830	COG0475	glutathione-regulated potassium exporter activity
LHJ63_RS08830	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LHJ63_RS08840	COG1473	amidohydrolase
LHJ63_RS08850	COG2831	hemolysin activation secretion protein
LHJ63_RS08855	COG3210	domain, Protein
LHJ63_RS08885	COG2188	Transcriptional regulator
LHJ63_RS08900	COG0583	DNA-binding transcription factor activity
LHJ63_RS08930	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LHJ63_RS08960	COG1566	PFAM secretion protein HlyD family protein
LHJ63_RS08975	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS08980	COG0129	dihydroxy-acid dehydratase activity
LHJ63_RS08990	COG0583	DNA-binding transcription factor activity
LHJ63_RS08995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LHJ63_RS09005	COG2084	Dehydrogenase
LHJ63_RS09010	COG2207	Transcriptional regulator
LHJ63_RS09025	COG1064	alcohol dehydrogenase
LHJ63_RS09035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LHJ63_RS09040	COG1120	ATPase activity
LHJ63_RS09060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHJ63_RS09180	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LHJ63_RS09230	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS09245	COG2207	Transcriptional regulator
LHJ63_RS09255	COG2205	protein histidine kinase activity
LHJ63_RS09260	COG0745	RESPONSE REGULATOR receiver
LHJ63_RS09265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHJ63_RS09270	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LHJ63_RS09275	COG1538	Outer membrane efflux protein
LHJ63_RS09285	COG2072	flavoprotein involved in K transport
LHJ63_RS09305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LHJ63_RS09325	COG3539	Fimbrial protein
LHJ63_RS09355	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LHJ63_RS09365	COG0753	catalase activity
LHJ63_RS09380	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LHJ63_RS09440	COG3433	isochorismatase activity
LHJ63_RS09440	COG1535	isochorismatase
LHJ63_RS09445	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS09450	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LHJ63_RS09455	COG4149	molybdate abc transporter
LHJ63_RS09460	COG0725	ABC transporter, periplasmic molybdate-binding protein
LHJ63_RS09470	COG4638	Rieske (2fe-2S)
LHJ63_RS09475	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LHJ63_RS09480	COG0543	2 iron, 2 sulfur cluster binding
LHJ63_RS09480	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LHJ63_RS09505	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS09520	COG2207	Transcriptional regulator
LHJ63_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS09535	COG2610	gluconate transmembrane transporter activity
LHJ63_RS09545	COG0583	DNA-binding transcription factor activity
LHJ63_RS09555	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LHJ63_RS09560	COG2031	fatty acid transporter
LHJ63_RS09565	COG0183	Belongs to the thiolase family
LHJ63_RS09570	COG0583	DNA-binding transcription factor activity
LHJ63_RS09575	COG0583	DNA-binding transcription factor activity
LHJ63_RS09590	COG1027	Aspartate ammonia-lyase
LHJ63_RS09600	COG0477	Major facilitator Superfamily
LHJ63_RS09620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LHJ63_RS09625	COG4521	taurine ABC transporter
LHJ63_RS09640	COG2188	Transcriptional regulator
LHJ63_RS09650	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LHJ63_RS09655	COG1733	regulation of RNA biosynthetic process
LHJ63_RS09660	COG2207	Transcriptional regulator
LHJ63_RS09660	COG3708	Transcriptional regulator
LHJ63_RS09675	COG0730	response to heat
LHJ63_RS09690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LHJ63_RS09690	COG3453	Protein conserved in bacteria
LHJ63_RS09700	COG3781	membrane
LHJ63_RS09705	COG1063	alcohol dehydrogenase
LHJ63_RS09715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LHJ63_RS09720	COG0508	dehydrogenase complex catalyzes the overall conversion of
LHJ63_RS09725	COG0022	dehydrogenase e1 component
LHJ63_RS09730	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LHJ63_RS09735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LHJ63_RS09750	COG3706	GGDEF domain
LHJ63_RS09765	COG0133	tryptophan synthase activity
LHJ63_RS09775	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LHJ63_RS09810	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LHJ63_RS09835	COG2226	methyltransferase
LHJ63_RS09895	COG0842	Transport permease protein
LHJ63_RS09900	COG0842	Transport permease protein
LHJ63_RS09905	COG1131	(ABC) transporter
LHJ63_RS09920	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LHJ63_RS09925	COG4773	Receptor
LHJ63_RS09945	COG0730	response to heat
LHJ63_RS09950	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LHJ63_RS09970	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LHJ63_RS09985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LHJ63_RS10025	COG4264	IucA IucC family
LHJ63_RS10030	COG4264	IucA IucC family
LHJ63_RS10050	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LHJ63_RS10065	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS10070	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS10075	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LHJ63_RS10080	COG2207	Transcriptional regulator
LHJ63_RS10085	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LHJ63_RS10090	COG0776	regulation of translation
LHJ63_RS10115	COG0822	iron-sulfur transferase activity
LHJ63_RS10120	COG0316	Belongs to the HesB IscA family
LHJ63_RS10150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LHJ63_RS10170	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LHJ63_RS10175	COG0702	epimerase
LHJ63_RS10210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LHJ63_RS10220	COG0339	signal peptide processing
LHJ63_RS10270	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LHJ63_RS10330	COG1196	nuclear chromosome segregation
LHJ63_RS10330	COG0741	lytic transglycosylase activity
LHJ63_RS10330	COG0739	heme binding
LHJ63_RS10390	COG4695	Portal protein
LHJ63_RS10480	COG0305	Participates in initiation and elongation during chromosome replication
LHJ63_RS10545	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LHJ63_RS10575	COG0776	regulation of translation
LHJ63_RS10640	COG0084	hydrolase, TatD family'
LHJ63_RS10660	COG1663	tetraacyldisaccharide 4'-kinase activity
LHJ63_RS10665	COG1132	(ABC) transporter
LHJ63_RS10675	COG0811	peptide transport
LHJ63_RS10680	COG1475	DNA binding
LHJ63_RS10685	COG1192	Involved in chromosome partitioning
LHJ63_RS10695	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LHJ63_RS10710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LHJ63_RS10715	COG0191	fructose-bisphosphate aldolase activity
LHJ63_RS10735	COG0424	maF-like protein
LHJ63_RS10740	COG2850	peptidyl-arginine hydroxylation
LHJ63_RS10750	COG0640	Transcriptional regulator
LHJ63_RS10765	COG3619	membrane
LHJ63_RS10770	COG3122	Protein conserved in bacteria
LHJ63_RS10775	COG1132	(ABC) transporter
LHJ63_RS10795	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LHJ63_RS10800	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LHJ63_RS10810	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LHJ63_RS10810	COG0506	proline dehydrogenase activity
LHJ63_RS10810	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LHJ63_RS10815	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LHJ63_RS10830	COG3698	Phosphodiester glycosidase
LHJ63_RS10840	COG2353	YceI-like domain
LHJ63_RS10850	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LHJ63_RS10895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LHJ63_RS10895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LHJ63_RS10920	COG3539	Fimbrial protein
LHJ63_RS10925	COG3121	Chaperone
LHJ63_RS10950	COG0697	spore germination
LHJ63_RS10960	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LHJ63_RS10970	COG0583	DNA-binding transcription factor activity
LHJ63_RS10990	COG1309	transcriptional regulator
LHJ63_RS11005	COG1522	sequence-specific DNA binding
LHJ63_RS11015	COG1126	abc transporter atp-binding protein
LHJ63_RS11020	COG0765	amino acid transport
LHJ63_RS11025	COG0765	amino acid transport
LHJ63_RS11055	COG1464	Belongs to the NlpA lipoprotein family
LHJ63_RS11065	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LHJ63_RS11070	COG2011	ABC-type metal ion transport system permease component
LHJ63_RS11075	COG0012	GTP binding
LHJ63_RS11100	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LHJ63_RS11140	COG0386	Belongs to the glutathione peroxidase family
LHJ63_RS11150	COG0436	Aminotransferase
LHJ63_RS11190	COG3634	alkyl hydroperoxide reductase activity
LHJ63_RS11205	COG0583	DNA-binding transcription factor activity
LHJ63_RS11210	COG0798	PFAM Bile acid sodium symporter
LHJ63_RS11215	COG0640	Transcriptional regulator
LHJ63_RS11230	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LHJ63_RS11240	COG0583	DNA-binding transcription factor activity
LHJ63_RS11250	COG1953	Uracil, thiamine, allantoin
LHJ63_RS11260	COG2175	clavaminate synthase activity
LHJ63_RS11265	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LHJ63_RS11270	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LHJ63_RS11275	COG4521	taurine ABC transporter
LHJ63_RS11285	COG0477	Major facilitator Superfamily
LHJ63_RS11305	COG1271	oxidase subunit
LHJ63_RS11310	COG1294	oxidase, subunit
LHJ63_RS11320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LHJ63_RS11340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LHJ63_RS11360	COG3052	prosthetic group binding
LHJ63_RS11365	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LHJ63_RS11375	COG2814	Major facilitator Superfamily
LHJ63_RS11395	COG1346	cytolysis
LHJ63_RS11405	COG0583	DNA-binding transcription factor activity
LHJ63_RS11410	COG0625	glutathione transferase activity
LHJ63_RS11415	COG0625	glutathione transferase activity
LHJ63_RS11420	COG0583	DNA-binding transcription factor activity
LHJ63_RS11435	COG1045	serine acetyltransferase
LHJ63_RS11440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LHJ63_RS11445	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LHJ63_RS11455	COG1280	lysine exporter protein (LysE YggA)
LHJ63_RS11470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LHJ63_RS11475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LHJ63_RS11480	COG1126	abc transporter atp-binding protein
LHJ63_RS11485	COG0765	amino acid transport
LHJ63_RS11490	COG0765	amino acid transport
LHJ63_RS11510	COG0784	Response regulator, receiver
LHJ63_RS11510	COG2205	protein histidine kinase activity
LHJ63_RS11530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LHJ63_RS11550	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS11600	COG0583	DNA-binding transcription factor activity
LHJ63_RS11620	COG0318	PFAM AMP-dependent synthetase and ligase
LHJ63_RS11625	COG1309	transcriptional regulator
LHJ63_RS11630	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS11635	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LHJ63_RS11640	COG1024	Enoyl-CoA hydratase
LHJ63_RS11645	COG4770	biotin carboxylase activity
LHJ63_RS11655	COG0583	DNA-binding transcription factor activity
LHJ63_RS11670	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS11680	COG2814	Major facilitator Superfamily
LHJ63_RS11690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LHJ63_RS11695	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LHJ63_RS11700	COG2814	Major facilitator Superfamily
LHJ63_RS11705	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS11710	COG1024	Enoyl-CoA hydratase
LHJ63_RS11715	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS11720	COG1250	3-hydroxyacyl-CoA dehydrogenase
LHJ63_RS11725	COG0183	Belongs to the thiolase family
LHJ63_RS11735	COG2814	Major facilitator Superfamily
LHJ63_RS11745	COG1024	Enoyl-CoA hydratase
LHJ63_RS11760	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS11765	COG2814	Major facilitator Superfamily
LHJ63_RS11770	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LHJ63_RS11775	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LHJ63_RS11790	COG3842	ATPase activity
LHJ63_RS11795	COG1840	ABC-type Fe3 transport system, periplasmic component
LHJ63_RS11805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LHJ63_RS11810	COG1414	Transcriptional regulator
LHJ63_RS11820	COG0583	DNA-binding transcription factor activity
LHJ63_RS11825	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LHJ63_RS11830	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS11840	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LHJ63_RS11850	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS11855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHJ63_RS11860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LHJ63_RS11865	COG2267	carboxylic ester hydrolase activity
LHJ63_RS11885	COG3038	cytochrome b561
LHJ63_RS11890	COG0753	catalase activity
LHJ63_RS11925	COG2050	protein possibly involved in aromatic compounds catabolism
LHJ63_RS11935	COG3327	negative regulation of DNA-templated transcription, initiation
LHJ63_RS11940	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LHJ63_RS11945	COG0183	Belongs to the thiolase family
LHJ63_RS11950	COG1250	3-hydroxyacyl-CoA dehydrogenase
LHJ63_RS11955	COG1024	Enoyl-CoA hydratase
LHJ63_RS11960	COG1024	Enoyl-CoA hydratase
LHJ63_RS11965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LHJ63_RS11970	COG2151	metal-sulfur cluster biosynthetic enzyme
LHJ63_RS11975	COG3396	Phenylacetate-CoA oxygenase
LHJ63_RS11980	COG3460	Phenylacetate-CoA oxygenase
LHJ63_RS11985	COG3396	Phenylacetate-CoA oxygenase
LHJ63_RS11990	COG2030	dehydratase
LHJ63_RS11990	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS11995	COG1760	l-serine dehydratase
LHJ63_RS12000	COG0531	amino acid
LHJ63_RS12005	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS12020	COG0446	pyridine nucleotide-disulphide oxidoreductase
LHJ63_RS12030	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LHJ63_RS12050	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHJ63_RS12060	COG0789	Transcriptional regulator
LHJ63_RS12075	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LHJ63_RS12090	COG2807	transmembrane transport
LHJ63_RS12095	COG0590	tRNA wobble adenosine to inosine editing
LHJ63_RS12215	COG1116	anion transmembrane transporter activity
LHJ63_RS12220	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LHJ63_RS12230	COG0864	Transcriptional regulator
LHJ63_RS12250	COG2249	NAD(P)H dehydrogenase (quinone) activity
LHJ63_RS12255	COG0439	Biotin carboxylase
LHJ63_RS12270	COG1063	alcohol dehydrogenase
LHJ63_RS12280	COG1309	transcriptional regulator
LHJ63_RS12300	COG0038	chloride channel
LHJ63_RS12305	COG4770	biotin carboxylase activity
LHJ63_RS12325	COG1914	H( )-stimulated, divalent metal cation uptake system
LHJ63_RS12330	COG0583	DNA-binding transcription factor activity
LHJ63_RS12380	COG1250	3-hydroxyacyl-CoA dehydrogenase
LHJ63_RS12400	COG2814	Major facilitator Superfamily
LHJ63_RS12415	COG1560	Kdo2-lipid A biosynthetic process
LHJ63_RS12425	COG5006	permease, DMT superfamily
LHJ63_RS12430	COG1522	sequence-specific DNA binding
LHJ63_RS12445	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LHJ63_RS12455	COG4122	O-methyltransferase activity
LHJ63_RS12485	COG1538	Outer membrane efflux protein
LHJ63_RS12490	COG1137	ATPase activity
LHJ63_RS12495	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LHJ63_RS12505	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LHJ63_RS12510	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LHJ63_RS12510	COG0517	IMP dehydrogenase activity
LHJ63_RS12545	COG2814	Major facilitator Superfamily
LHJ63_RS12580	COG1278	Cold shock
LHJ63_RS12585	COG1280	lysine exporter protein (LysE YggA)
LHJ63_RS12615	COG1570	exodeoxyribonuclease VII activity
LHJ63_RS12665	COG0583	DNA-binding transcription factor activity
LHJ63_RS12675	COG4638	Rieske (2fe-2S)
LHJ63_RS12680	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LHJ63_RS12685	COG0543	2 iron, 2 sulfur cluster binding
LHJ63_RS12685	COG0633	Ferredoxin
LHJ63_RS12690	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS12695	COG3135	benzoate transporter
LHJ63_RS12700	COG2814	Major facilitator Superfamily
LHJ63_RS12715	COG1643	Atp-dependent helicase
LHJ63_RS12720	COG0450	alkyl hydroperoxide reductase
LHJ63_RS12730	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LHJ63_RS12740	COG3634	alkyl hydroperoxide reductase activity
LHJ63_RS12760	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LHJ63_RS12765	COG0625	glutathione transferase activity
LHJ63_RS12775	COG2885	chlorophyll binding
LHJ63_RS12810	COG0542	response to heat
LHJ63_RS12825	COG1765	OsmC-like protein
LHJ63_RS12845	COG0667	Aldo Keto reductase
LHJ63_RS12860	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LHJ63_RS12870	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LHJ63_RS12880	COG0527	aspartate kinase activity
LHJ63_RS12890	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LHJ63_RS12900	COG3038	cytochrome b561
LHJ63_RS12905	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LHJ63_RS12910	COG2252	PERMEase
LHJ63_RS12920	COG2072	flavoprotein involved in K transport
LHJ63_RS12935	COG1741	Belongs to the pirin family
LHJ63_RS12940	COG1309	transcriptional regulator
LHJ63_RS12960	COG1902	pentaerythritol trinitrate reductase activity
LHJ63_RS12960	COG0446	pyridine nucleotide-disulphide oxidoreductase
LHJ63_RS12970	COG2203	Gaf domain
LHJ63_RS12970	COG3706	GGDEF domain
LHJ63_RS12970	COG4251	negative regulation of phosphorylation
LHJ63_RS12970	COG5001	Diguanylate cyclase
LHJ63_RS12980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LHJ63_RS13000	COG4172	Belongs to the ABC transporter superfamily
LHJ63_RS13005	COG4239	(ABC) transporter, permease
LHJ63_RS13010	COG4174	ABC transporter (Permease)
LHJ63_RS13020	COG1388	LysM domain
LHJ63_RS13020	COG0741	lytic transglycosylase activity
LHJ63_RS13020	COG1388	LysM domain
LHJ63_RS13020	COG0741	lytic transglycosylase activity
LHJ63_RS13025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LHJ63_RS13065	COG0583	DNA-binding transcription factor activity
LHJ63_RS13070	COG1279	arginine transmembrane transporter activity
LHJ63_RS13090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LHJ63_RS13095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LHJ63_RS13100	COG0006	proline dipeptidase activity
LHJ63_RS13140	COG2194	sulfuric ester hydrolase activity
LHJ63_RS13185	COG0739	heme binding
LHJ63_RS13515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LHJ63_RS13540	COG3384	dioxygenase
LHJ63_RS13550	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LHJ63_RS13555	COG2878	Part of a membrane complex involved in electron transport
LHJ63_RS13560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LHJ63_RS13585	COG0768	penicillin binding
LHJ63_RS13590	COG0742	ribosomal rna small subunit methyltransferase
LHJ63_RS13605	COG0830	nickel cation binding
LHJ63_RS13615	COG0804	urea catabolic process
LHJ63_RS13655	COG1253	flavin adenine dinucleotide binding
LHJ63_RS13660	COG2851	Citrate transporter
LHJ63_RS13715	COG1773	rubredoxin
LHJ63_RS13720	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LHJ63_RS13730	COG0583	DNA-binding transcription factor activity
LHJ63_RS13755	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LHJ63_RS13760	COG4181	ATPase activity
LHJ63_RS13805	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LHJ63_RS13825	COG0306	phosphate transporter
LHJ63_RS13835	COG3958	Transketolase
LHJ63_RS13840	COG3959	Transketolase, thiamine diphosphate binding domain
LHJ63_RS13845	COG2271	Major facilitator Superfamily
LHJ63_RS13850	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS13855	COG0583	DNA-binding transcription factor activity
LHJ63_RS13870	COG2223	nitrite transmembrane transporter activity
LHJ63_RS13875	COG2207	Transcriptional regulator
LHJ63_RS13880	COG2066	Belongs to the glutaminase family
LHJ63_RS13885	COG0242	peptide deformylase activity
LHJ63_RS13890	COG0477	Major facilitator Superfamily
LHJ63_RS13900	COG0028	Belongs to the TPP enzyme family
LHJ63_RS13915	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS13920	COG2267	carboxylic ester hydrolase activity
LHJ63_RS13930	COG2271	Major facilitator Superfamily
LHJ63_RS13935	COG0446	pyridine nucleotide-disulphide oxidoreductase
LHJ63_RS13945	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS13965	COG1414	Transcriptional regulator
LHJ63_RS13980	COG1024	Enoyl-CoA hydratase
LHJ63_RS13990	COG1215	transferase activity, transferring glycosyl groups
LHJ63_RS13995	COG0726	polysaccharide deacetylase
LHJ63_RS13995	COG1649	PFAM Uncharacterised BCR, COG1649
LHJ63_RS14005	COG4681	YaeQ
LHJ63_RS14015	COG0523	cobalamin synthesis protein
LHJ63_RS14025	COG1607	acyl-coa hydrolase
LHJ63_RS14035	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LHJ63_RS14040	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LHJ63_RS14045	COG1309	transcriptional regulator
LHJ63_RS14070	COG2040	homocysteine
LHJ63_RS14075	COG0531	amino acid
LHJ63_RS14130	COG1595	DNA-templated transcription, initiation
LHJ63_RS14140	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHJ63_RS14145	COG0477	Major facilitator Superfamily
LHJ63_RS14165	COG0084	hydrolase, TatD family'
LHJ63_RS14205	COG0629	single-stranded DNA binding
LHJ63_RS14260	COG0582	viral genome integration into host DNA
LHJ63_RS14365	COG0592	DNA-directed DNA polymerase activity
LHJ63_RS14405	COG2026	Addiction module toxin, RelE StbE family
LHJ63_RS14595	COG1484	DNA-dependent DNA replication
LHJ63_RS14685	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LHJ63_RS14755	COG0405	Gamma-glutamyltransferase
LHJ63_RS14760	COG2814	Major facilitator Superfamily
LHJ63_RS14770	COG2050	protein possibly involved in aromatic compounds catabolism
LHJ63_RS14785	COG1090	epimerase
LHJ63_RS14805	COG0420	3'-5' exonuclease activity
LHJ63_RS14830	COG0735	belongs to the Fur family
LHJ63_RS14835	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LHJ63_RS14855	COG0121	glutamine amidotransferase
LHJ63_RS14870	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LHJ63_RS14880	COG0210	DNA helicase
LHJ63_RS14885	COG2885	chlorophyll binding
LHJ63_RS14890	COG0204	Acyl-transferase
LHJ63_RS14905	COG2894	cell division
LHJ63_RS14925	COG1280	lysine exporter protein (LysE YggA)
LHJ63_RS14930	COG1674	ftsk spoiiie
LHJ63_RS14930	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LHJ63_RS14935	COG0492	ferredoxin-NADP+ reductase activity
LHJ63_RS14940	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LHJ63_RS14950	COG0456	acetyltransferase
LHJ63_RS14995	COG1981	membrane
LHJ63_RS15010	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LHJ63_RS15010	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LHJ63_RS15030	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS15040	COG0657	acetylesterase activity
LHJ63_RS15050	COG0473	3-isopropylmalate dehydrogenase activity
LHJ63_RS15055	COG0583	DNA-binding transcription factor activity
LHJ63_RS15075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LHJ63_RS15100	COG0564	pseudouridine synthase activity
LHJ63_RS15110	COG0358	DNA primase activity
LHJ63_RS15125	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LHJ63_RS15155	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LHJ63_RS15185	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LHJ63_RS15195	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LHJ63_RS15195	COG0352	thiamine-phosphate diphosphorylase activity
LHJ63_RS15195	COG0351	phosphomethylpyrimidine kinase
LHJ63_RS15200	COG1652	LysM domain
LHJ63_RS15225	COG1399	metal-binding, possibly nucleic acid-binding protein
LHJ63_RS15230	COG3101	peptidyl-lysine hydroxylation
LHJ63_RS15235	COG0009	L-threonylcarbamoyladenylate synthase
LHJ63_RS15240	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LHJ63_RS15245	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LHJ63_RS15260	COG4106	trans-aconitate 2-methyltransferase activity
LHJ63_RS15275	COG2226	methyltransferase
LHJ63_RS15275	COG0596	Alpha beta hydrolase
LHJ63_RS15275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LHJ63_RS15280	COG1877	trehalose-phosphatase activity
LHJ63_RS15285	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LHJ63_RS15290	COG2223	nitrite transmembrane transporter activity
LHJ63_RS15310	COG1196	nuclear chromosome segregation
LHJ63_RS15320	COG0730	response to heat
LHJ63_RS15335	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LHJ63_RS15345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHJ63_RS15395	COG0489	protein tyrosine kinase activity
LHJ63_RS15405	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LHJ63_RS15405	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LHJ63_RS15435	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LHJ63_RS15440	COG2081	HI0933 family
LHJ63_RS15450	COG0668	transmembrane transport
LHJ63_RS15470	COG0583	DNA-binding transcription factor activity
LHJ63_RS15490	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LHJ63_RS15495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LHJ63_RS15525	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LHJ63_RS15565	COG0745	RESPONSE REGULATOR receiver
LHJ63_RS15585	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LHJ63_RS15595	COG2205	protein histidine kinase activity
LHJ63_RS15605	COG3328	transposase activity
LHJ63_RS15670	COG4993	Dehydrogenase
LHJ63_RS15695	COG0384	phenazine biosynthesis protein PhzF
LHJ63_RS15720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LHJ63_RS15735	COG0583	DNA-binding transcription factor activity
LHJ63_RS15765	COG0583	DNA-binding transcription factor activity
LHJ63_RS15780	COG0583	DNA-binding transcription factor activity
LHJ63_RS15785	COG1053	succinate dehydrogenase
LHJ63_RS15795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LHJ63_RS15800	COG2814	Major facilitator Superfamily
LHJ63_RS15805	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS15810	COG0583	DNA-binding transcription factor activity
LHJ63_RS15815	COG1063	alcohol dehydrogenase
LHJ63_RS15845	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LHJ63_RS15850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LHJ63_RS15855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LHJ63_RS15870	COG3667	copper resistance
LHJ63_RS15875	COG2132	Multicopper oxidase
LHJ63_RS15885	COG0561	phosphatase activity
LHJ63_RS15890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LHJ63_RS15915	COG1214	PFAM Peptidase M22, glycoprotease
LHJ63_RS15970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LHJ63_RS15980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LHJ63_RS15985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LHJ63_RS15990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LHJ63_RS16050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LHJ63_RS16060	COG1846	Transcriptional regulator
LHJ63_RS16065	COG1764	response to oxidative stress
LHJ63_RS16115	COG0037	tRNA processing
LHJ63_RS16125	COG0248	Ppx GppA phosphatase
LHJ63_RS16155	COG0072	phenylalanine-tRNA ligase activity
LHJ63_RS16200	COG1238	metal cluster binding
LHJ63_RS16205	COG0625	glutathione transferase activity
LHJ63_RS16220	COG0318	PFAM AMP-dependent synthetase and ligase
LHJ63_RS16225	COG3028	Belongs to the UPF0307 family
LHJ63_RS16230	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LHJ63_RS16250	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LHJ63_RS16255	COG0617	tRNA 3'-terminal CCA addition
LHJ63_RS16260	COG1555	photosystem II stabilization
LHJ63_RS16265	COG3956	TIGRFAM MazG family protein
LHJ63_RS16275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LHJ63_RS16295	COG5002	protein histidine kinase activity
LHJ63_RS16295	COG2205	protein histidine kinase activity
LHJ63_RS16295	COG0784	Response regulator, receiver
LHJ63_RS16300	COG1024	Enoyl-CoA hydratase
LHJ63_RS16305	COG2084	Dehydrogenase
LHJ63_RS16310	COG3622	Belongs to the hyi family
LHJ63_RS16340	COG0697	spore germination
LHJ63_RS16350	COG2814	Major facilitator Superfamily
LHJ63_RS16355	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LHJ63_RS16365	COG0583	DNA-binding transcription factor activity
LHJ63_RS16375	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LHJ63_RS16390	COG0084	hydrolase, TatD family'
LHJ63_RS16405	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LHJ63_RS16435	COG0440	acetolactate synthase activity
LHJ63_RS16440	COG0028	Belongs to the TPP enzyme family
LHJ63_RS16465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LHJ63_RS16470	COG1136	(ABC) transporter
LHJ63_RS16470	COG0577	efflux transmembrane transporter activity
LHJ63_RS16475	COG1538	Outer membrane efflux protein
LHJ63_RS16490	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LHJ63_RS16495	COG1162	GTPase activity
LHJ63_RS16505	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LHJ63_RS16525	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LHJ63_RS16530	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS16570	COG2986	histidine ammonia-lyase
LHJ63_RS16585	COG0318	PFAM AMP-dependent synthetase and ligase
LHJ63_RS16595	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LHJ63_RS16640	COG1426	Protein conserved in bacteria
LHJ63_RS16675	COG0793	Belongs to the peptidase S41A family
LHJ63_RS16690	COG2267	carboxylic ester hydrolase activity
LHJ63_RS16700	COG1012	belongs to the aldehyde dehydrogenase family
LHJ63_RS16705	COG3265	gluconokinase activity
LHJ63_RS16715	COG0800	Aldolase
LHJ63_RS16730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LHJ63_RS16735	COG0857	belongs to the CobB CobQ family
LHJ63_RS16735	COG0280	phosphate acetyltransferase
LHJ63_RS16740	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LHJ63_RS16740	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LHJ63_RS16760	COG0740	serine-type endopeptidase activity
LHJ63_RS16770	COG4774	siderophore transport
LHJ63_RS16780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LHJ63_RS16790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LHJ63_RS16790	COG2813	Specifically methylates the guanine in position
LHJ63_RS16890	COG0788	formyltetrahydrofolate deformylase activity
LHJ63_RS16915	COG4651	solute:proton antiporter activity
LHJ63_RS16915	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LHJ63_RS16935	COG0724	RNA recognition motif
LHJ63_RS16940	COG0210	DNA helicase
LHJ63_RS16965	COG1733	regulation of RNA biosynthetic process
LHJ63_RS16975	COG2900	Belongs to the SlyX family
LHJ63_RS16980	COG0488	(ABC) transporter
LHJ63_RS16985	COG1280	lysine exporter protein (LysE YggA)
LHJ63_RS16990	COG1560	Kdo2-lipid A biosynthetic process
LHJ63_RS17000	COG1301	dicarboxylic acid transport
LHJ63_RS17055	COG0473	3-isopropylmalate dehydrogenase activity
LHJ63_RS17120	COG0583	DNA-binding transcription factor activity
LHJ63_RS17130	COG0625	glutathione transferase activity
LHJ63_RS17135	COG2378	regulation of single-species biofilm formation
LHJ63_RS17140	COG0546	phosphoglycolate phosphatase activity
LHJ63_RS17150	COG1530	ribonuclease E activity
LHJ63_RS17155	COG0318	PFAM AMP-dependent synthetase and ligase
LHJ63_RS17170	COG0583	DNA-binding transcription factor activity
LHJ63_RS17175	COG4221	oxidoreductase activity
LHJ63_RS17180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LHJ63_RS17190	COG0534	Mate efflux family protein
LHJ63_RS17205	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LHJ63_RS17245	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LHJ63_RS17250	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LHJ63_RS17265	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LHJ63_RS17275	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LHJ63_RS17275	COG0644	oxidoreductase
LHJ63_RS17280	COG0425	Belongs to the sulfur carrier protein TusA family
LHJ63_RS17285	COG4535	Mg2 and Co2 transporter CorC
LHJ63_RS17295	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LHJ63_RS17315	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LHJ63_RS17320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LHJ63_RS17320	COG0475	glutathione-regulated potassium exporter activity
LHJ63_RS17325	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LHJ63_RS17335	COG0484	heat shock protein binding
LHJ63_RS17340	COG0789	Transcriptional regulator
LHJ63_RS17345	COG0598	Magnesium transport protein CorA
LHJ63_RS17360	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LHJ63_RS17365	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LHJ63_RS17370	COG1074	ATP-dependent DNA helicase activity
LHJ63_RS17375	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LHJ63_RS17395	COG2226	methyltransferase
LHJ63_RS17410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LHJ63_RS17415	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LHJ63_RS17430	COG2111	Na H antiporter
LHJ63_RS17430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LHJ63_RS17435	COG1006	Multisubunit Na H antiporter MnhC subunit
LHJ63_RS17440	COG0651	ATP synthesis coupled electron transport
LHJ63_RS17445	COG1863	multisubunit Na H antiporter MnhE subunit
LHJ63_RS17450	COG2212	antiporter activity
LHJ63_RS17455	COG1320	monovalent cation:proton antiporter activity
LHJ63_RS17470	COG0195	Participates in both transcription termination and antitermination
LHJ63_RS17525	COG0237	dephospho-CoA kinase activity
LHJ63_RS17535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LHJ63_RS17550	COG0497	DNA recombination
LHJ63_RS17560	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LHJ63_RS17590	COG2169	Transcriptional regulator
LHJ63_RS17590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LHJ63_RS17595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LHJ63_RS17660	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LHJ63_RS17675	COG0326	Molecular chaperone. Has ATPase activity
LHJ63_RS17690	COG2056	Na+-H+ antiporter family
LHJ63_RS17695	COG0596	Alpha beta hydrolase
LHJ63_RS17790	COG0546	phosphoglycolate phosphatase activity
LHJ63_RS17795	COG1716	ATPase activity
LHJ63_RS17840	COG0181	hydroxymethylbilane synthase activity
LHJ63_RS17850	COG3275	phosphorelay sensor kinase activity
LHJ63_RS17870	COG1538	Outer membrane efflux protein
LHJ63_RS17875	COG0697	spore germination
LHJ63_RS17900	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LHJ63_RS17905	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LHJ63_RS17910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LHJ63_RS17915	COG0772	Belongs to the SEDS family
LHJ63_RS17940	COG4974	Belongs to the 'phage' integrase family
LHJ63_RS17945	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LHJ63_RS17955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LHJ63_RS17965	COG2197	response regulator
LHJ63_RS17980	COG0793	Belongs to the peptidase S41A family
LHJ63_RS17985	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LHJ63_RS17990	COG0795	lipopolysaccharide-transporting ATPase activity
LHJ63_RS18030	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LHJ63_RS18030	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LHJ63_RS18040	COG0004	ammonium transporteR
LHJ63_RS18045	COG0347	Belongs to the P(II) protein family
LHJ63_RS18120	COG1061	Type III restriction enzyme res subunit
LHJ63_RS18125	COG1002	Type II restriction enzyme, methylase subunits
LHJ63_RS18135	COG0659	secondary active sulfate transmembrane transporter activity
LHJ63_RS18140	COG0589	response to stress
LHJ63_RS18185	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LHJ63_RS18205	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LHJ63_RS18220	COG0318	PFAM AMP-dependent synthetase and ligase
LHJ63_RS18230	COG0477	Major facilitator Superfamily
LHJ63_RS18235	COG2860	membrane
LHJ63_RS18245	COG1253	flavin adenine dinucleotide binding
LHJ63_RS18265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LHJ63_RS18305	COG0655	NAD(P)H dehydrogenase (quinone) activity
LHJ63_RS18315	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LHJ63_RS18385	COG0758	DNA mediated transformation
LHJ63_RS18395	COG0697	spore germination
LHJ63_RS18400	COG1309	transcriptional regulator
LHJ63_RS18415	COG0386	Belongs to the glutathione peroxidase family
LHJ63_RS18480	COG1121	(ABC) transporter
LHJ63_RS18485	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LHJ63_RS18490	COG1280	lysine exporter protein (LysE YggA)
LHJ63_RS18495	COG2837	iron assimilation
LHJ63_RS18505	COG0281	malic enzyme
LHJ63_RS18550	COG0519	Catalyzes the synthesis of GMP from XMP
LHJ63_RS18550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LHJ63_RS18555	COG4399	Belongs to the UPF0754 family
LHJ63_RS18560	COG2259	Doxx family
LHJ63_RS18565	COG0586	Pfam SNARE associated Golgi protein
LHJ63_RS18580	COG1192	Involved in chromosome partitioning
LHJ63_RS18590	COG0271	Belongs to the BolA IbaG family
LHJ63_RS18610	COG2267	carboxylic ester hydrolase activity
LHJ63_RS18630	COG3321	synthase
LHJ63_RS18630	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LHJ63_RS18630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LHJ63_RS18630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LHJ63_RS18635	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS18645	COG2197	response regulator
LHJ63_RS18655	COG3916	Acyl-homoserine-lactone synthase
LHJ63_RS18660	COG0477	Major facilitator Superfamily
LHJ63_RS18665	COG1024	Enoyl-CoA hydratase
LHJ63_RS18670	COG1024	Enoyl-CoA hydratase
LHJ63_RS18675	COG1960	acyl-CoA dehydrogenase activity
LHJ63_RS18680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LHJ63_RS18700	COG1113	amino acid transport
LHJ63_RS18705	COG1113	amino acid transport
LHJ63_RS18710	COG0251	oxidation-reduction process
LHJ63_RS18750	COG0564	pseudouridine synthase activity
LHJ63_RS18810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LHJ63_RS18825	COG1802	Transcriptional regulator
LHJ63_RS18835	COG1448	Aminotransferase
LHJ63_RS18850	COG1002	Type II restriction enzyme, methylase subunits
LHJ63_RS18855	COG1061	Type III restriction enzyme res subunit
LHJ63_RS18885	COG2186	Transcriptional regulator
LHJ63_RS18895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LHJ63_RS18900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LHJ63_RS18915	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LHJ63_RS18920	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LHJ63_RS18945	COG0438	transferase activity, transferring glycosyl groups
LHJ63_RS18975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LHJ63_RS19005	COG0728	peptidoglycan biosynthetic process
LHJ63_RS19010	COG3023	N-Acetylmuramoyl-L-alanine amidase
LHJ63_RS19065	COG0546	phosphoglycolate phosphatase activity
LHJ63_RS19070	COG1028	Short-chain dehydrogenase reductase Sdr
LHJ63_RS19090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LHJ63_RS19095	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LHJ63_RS19100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LHJ63_RS19105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LHJ63_RS19110	COG1116	anion transmembrane transporter activity
LHJ63_RS19115	COG1309	transcriptional regulator
LHJ63_RS19120	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LHJ63_RS19130	COG0196	riboflavin kinase activity
LHJ63_RS19135	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LHJ63_RS19145	COG1047	Peptidyl-prolyl cis-trans
LHJ63_RS19185	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LHJ63_RS19190	COG0657	acetylesterase activity
LHJ63_RS19210	COG0583	DNA-binding transcription factor activity
LHJ63_RS19240	COG2951	lytic endotransglycosylase activity
LHJ63_RS19245	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LHJ63_RS19260	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LHJ63_RS19270	COG0671	phosphoesterase, PA-phosphatase related
LHJ63_RS19275	COG0861	Integral membrane protein TerC family
LHJ63_RS19285	COG0754	glutathionylspermidine amidase activity
LHJ63_RS19295	COG0402	S-adenosylhomocysteine deaminase activity
LHJ63_RS19310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LHJ63_RS19315	COG1230	cation diffusion facilitator family transporter
LHJ63_RS19330	COG0706	membrane insertase activity
LHJ63_RS19450	COG1525	nuclease
LHJ63_RS19510	COG1475	DNA binding
LHJ63_RS19525	COG3853	Toxic anion resistance protein (TelA)
LHJ63_RS19630	COG0484	heat shock protein binding
LHJ63_RS19720	COG0741	lytic transglycosylase activity
LHJ63_RS19755	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process