locus-tag	class	description
FK728_RS00010	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FK728_RS00015	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FK728_RS00020	COG0596	Alpha beta hydrolase
FK728_RS00045	COG0488	(ABC) transporter
FK728_RS00050	COG0586	Pfam SNARE associated Golgi protein
FK728_RS00060	COG0187	DNA topoisomerase II activity
FK728_RS00070	COG0592	DNA-directed DNA polymerase activity
FK728_RS00095	COG0706	membrane insertase activity
FK728_RS00110	COG1230	cation diffusion facilitator family transporter
FK728_RS00115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK728_RS00130	COG0402	S-adenosylhomocysteine deaminase activity
FK728_RS00140	COG0754	glutathionylspermidine amidase activity
FK728_RS00150	COG0861	Integral membrane protein TerC family
FK728_RS00155	COG0671	phosphoesterase, PA-phosphatase related
FK728_RS00165	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FK728_RS00185	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FK728_RS00190	COG2951	lytic endotransglycosylase activity
FK728_RS00240	COG0657	acetylesterase activity
FK728_RS00245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FK728_RS00285	COG1047	Peptidyl-prolyl cis-trans
FK728_RS00295	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FK728_RS00300	COG0196	riboflavin kinase activity
FK728_RS00310	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FK728_RS00315	COG1309	transcriptional regulator
FK728_RS00320	COG1116	anion transmembrane transporter activity
FK728_RS00325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FK728_RS00330	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FK728_RS00335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK728_RS00340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK728_RS00360	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS00365	COG0546	phosphoglycolate phosphatase activity
FK728_RS00420	COG3023	N-Acetylmuramoyl-L-alanine amidase
FK728_RS00425	COG0728	peptidoglycan biosynthetic process
FK728_RS00455	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FK728_RS00465	COG1091	dTDP-4-dehydrorhamnose reductase activity
FK728_RS00470	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FK728_RS00480	COG2244	polysaccharide biosynthetic process
FK728_RS00495	COG0438	transferase activity, transferring glycosyl groups
FK728_RS00500	COG0463	Glycosyl transferase, family 2
FK728_RS00505	COG0110	maltose O-acetyltransferase activity
FK728_RS00520	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FK728_RS00525	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FK728_RS00545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK728_RS00555	COG2186	Transcriptional regulator
FK728_RS00565	COG0277	FAD linked oxidase domain protein
FK728_RS00570	COG1448	Aminotransferase
FK728_RS00580	COG1802	Transcriptional regulator
FK728_RS00595	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FK728_RS00635	COG2801	Transposase and inactivated derivatives
FK728_RS00685	COG0564	pseudouridine synthase activity
FK728_RS00725	COG0251	oxidation-reduction process
FK728_RS00730	COG1113	amino acid transport
FK728_RS00735	COG1113	amino acid transport
FK728_RS00755	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK728_RS00760	COG1960	acyl-CoA dehydrogenase activity
FK728_RS00765	COG1024	Enoyl-CoA hydratase
FK728_RS00770	COG1024	Enoyl-CoA hydratase
FK728_RS00775	COG0477	Major facilitator Superfamily
FK728_RS00780	COG3916	Acyl-homoserine-lactone synthase
FK728_RS00790	COG2197	response regulator
FK728_RS00800	COG1960	acyl-CoA dehydrogenase activity
FK728_RS00805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK728_RS00805	COG3321	synthase
FK728_RS00805	COG0300	oxidoreductase activity
FK728_RS00805	COG0318	PFAM AMP-dependent synthetase and ligase
FK728_RS00805	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS00825	COG2267	carboxylic ester hydrolase activity
FK728_RS00845	COG0271	Belongs to the BolA IbaG family
FK728_RS00855	COG1192	Involved in chromosome partitioning
FK728_RS00870	COG0586	Pfam SNARE associated Golgi protein
FK728_RS00875	COG2259	Doxx family
FK728_RS00880	COG4399	Belongs to the UPF0754 family
FK728_RS00885	COG0519	Catalyzes the synthesis of GMP from XMP
FK728_RS00885	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FK728_RS00930	COG0281	malic enzyme
FK728_RS00935	COG2837	iron assimilation
FK728_RS00940	COG1280	lysine exporter protein (LysE YggA)
FK728_RS00945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FK728_RS00950	COG1121	(ABC) transporter
FK728_RS01015	COG0386	Belongs to the glutathione peroxidase family
FK728_RS01030	COG1309	transcriptional regulator
FK728_RS01035	COG0697	spore germination
FK728_RS01075	COG4771	TonB-dependent receptor
FK728_RS01090	COG1309	transcriptional regulator
FK728_RS01125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FK728_RS01140	COG0655	NAD(P)H dehydrogenase (quinone) activity
FK728_RS01175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FK728_RS01185	COG0477	Major facilitator Superfamily
FK728_RS01195	COG1253	flavin adenine dinucleotide binding
FK728_RS01205	COG2860	membrane
FK728_RS01210	COG0477	Major facilitator Superfamily
FK728_RS01220	COG0318	PFAM AMP-dependent synthetase and ligase
FK728_RS01235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FK728_RS01250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FK728_RS01255	COG0235	Class ii aldolase
FK728_RS01260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_RS01265	COG0606	chelatase, subunit chli
FK728_RS01310	COG2217	Heavy metal translocating P-type atpase
FK728_RS01315	COG2205	protein histidine kinase activity
FK728_RS01330	COG2132	Multicopper oxidase
FK728_RS01355	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK728_RS01400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FK728_RS01435	COG0606	chelatase, subunit chli
FK728_RS01445	COG0347	Belongs to the P(II) protein family
FK728_RS01450	COG0004	ammonium transporteR
FK728_RS01460	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FK728_RS01460	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FK728_RS01500	COG0795	lipopolysaccharide-transporting ATPase activity
FK728_RS01505	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FK728_RS01510	COG0793	Belongs to the peptidase S41A family
FK728_RS01525	COG2197	response regulator
FK728_RS01535	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FK728_RS01545	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK728_RS01550	COG4974	Belongs to the 'phage' integrase family
FK728_RS01575	COG0772	Belongs to the SEDS family
FK728_RS01580	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FK728_RS01585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FK728_RS01590	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FK728_RS01615	COG0697	spore germination
FK728_RS01620	COG1538	Outer membrane efflux protein
FK728_RS01640	COG3275	phosphorelay sensor kinase activity
FK728_RS01650	COG0181	hydroxymethylbilane synthase activity
FK728_RS01695	COG1716	ATPase activity
FK728_RS01700	COG0546	phosphoglycolate phosphatase activity
FK728_RS01800	COG2056	Na+-H+ antiporter family
FK728_RS01815	COG0326	Molecular chaperone. Has ATPase activity
FK728_RS01830	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FK728_RS01900	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FK728_RS01905	COG2169	Transcriptional regulator
FK728_RS01905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FK728_RS01935	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FK728_RS01945	COG0497	DNA recombination
FK728_RS01960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FK728_RS01970	COG0237	dephospho-CoA kinase activity
FK728_RS02020	COG0195	Participates in both transcription termination and antitermination
FK728_RS02035	COG1320	monovalent cation:proton antiporter activity
FK728_RS02040	COG2212	antiporter activity
FK728_RS02045	COG1863	multisubunit Na H antiporter MnhE subunit
FK728_RS02050	COG0651	ATP synthesis coupled electron transport
FK728_RS02055	COG1006	Multisubunit Na H antiporter MnhC subunit
FK728_RS02060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FK728_RS02060	COG2111	Na H antiporter
FK728_RS02075	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FK728_RS02090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_RS02105	COG2226	methyltransferase
FK728_RS02125	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FK728_RS02130	COG1074	ATP-dependent DNA helicase activity
FK728_RS02135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FK728_RS02140	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FK728_RS02155	COG0598	Magnesium transport protein CorA
FK728_RS02160	COG0789	Transcriptional regulator
FK728_RS02165	COG0484	heat shock protein binding
FK728_RS02180	COG0475	glutathione-regulated potassium exporter activity
FK728_RS02180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FK728_RS02185	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FK728_RS02205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FK728_RS02215	COG4535	Mg2 and Co2 transporter CorC
FK728_RS02220	COG0425	Belongs to the sulfur carrier protein TusA family
FK728_RS02230	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FK728_RS02230	COG0644	oxidoreductase
FK728_RS02240	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FK728_RS02255	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK728_RS02260	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FK728_RS02270	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK728_RS02270	COG0493	'glutamate synthase
FK728_RS02295	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FK728_RS02310	COG0534	Mate efflux family protein
FK728_RS02320	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FK728_RS02325	COG4221	oxidoreductase activity
FK728_RS02330	COG0583	DNA-binding transcription factor activity
FK728_RS02345	COG0318	PFAM AMP-dependent synthetase and ligase
FK728_RS02350	COG1530	ribonuclease E activity
FK728_RS02365	COG0546	phosphoglycolate phosphatase activity
FK728_RS02370	COG2378	regulation of single-species biofilm formation
FK728_RS02375	COG0625	glutathione transferase activity
FK728_RS02385	COG0583	DNA-binding transcription factor activity
FK728_RS02440	COG0473	3-isopropylmalate dehydrogenase activity
FK728_RS02495	COG1301	dicarboxylic acid transport
FK728_RS02505	COG1560	Kdo2-lipid A biosynthetic process
FK728_RS02510	COG1280	lysine exporter protein (LysE YggA)
FK728_RS02520	COG0488	(ABC) transporter
FK728_RS02525	COG2900	Belongs to the SlyX family
FK728_RS02535	COG1733	regulation of RNA biosynthetic process
FK728_RS02560	COG0210	DNA helicase
FK728_RS02565	COG0724	RNA recognition motif
FK728_RS02585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FK728_RS02585	COG4651	solute:proton antiporter activity
FK728_RS02610	COG0788	formyltetrahydrofolate deformylase activity
FK728_RS02710	COG2813	Specifically methylates the guanine in position
FK728_RS02710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK728_RS02720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FK728_RS02730	COG4774	siderophore transport
FK728_RS02740	COG0740	serine-type endopeptidase activity
FK728_RS02760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FK728_RS02760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FK728_RS02765	COG0857	belongs to the CobB CobQ family
FK728_RS02765	COG0280	phosphate acetyltransferase
FK728_RS02770	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FK728_RS02780	COG0800	Aldolase
FK728_RS02790	COG3265	gluconokinase activity
FK728_RS02795	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS02805	COG2267	carboxylic ester hydrolase activity
FK728_RS02820	COG0793	Belongs to the peptidase S41A family
FK728_RS02855	COG1426	Protein conserved in bacteria
FK728_RS02895	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FK728_RS02905	COG1162	GTPase activity
FK728_RS02910	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FK728_RS02925	COG1538	Outer membrane efflux protein
FK728_RS02930	COG1136	(ABC) transporter
FK728_RS02930	COG0577	efflux transmembrane transporter activity
FK728_RS02935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_RS02965	COG0028	Belongs to the TPP enzyme family
FK728_RS02970	COG0440	acetolactate synthase activity
FK728_RS03005	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FK728_RS03020	COG0084	hydrolase, TatD family'
FK728_RS03035	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FK728_RS03045	COG0583	DNA-binding transcription factor activity
FK728_RS03055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FK728_RS03060	COG2814	Major facilitator Superfamily
FK728_RS03070	COG0697	spore germination
FK728_RS03100	COG3622	Belongs to the hyi family
FK728_RS03105	COG2084	Dehydrogenase
FK728_RS03110	COG1024	Enoyl-CoA hydratase
FK728_RS03115	COG0784	Response regulator, receiver
FK728_RS03115	COG2205	protein histidine kinase activity
FK728_RS03115	COG5002	protein histidine kinase activity
FK728_RS03135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FK728_RS03145	COG3956	TIGRFAM MazG family protein
FK728_RS03150	COG1555	photosystem II stabilization
FK728_RS03155	COG0617	tRNA 3'-terminal CCA addition
FK728_RS03160	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FK728_RS03180	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK728_RS03185	COG3028	Belongs to the UPF0307 family
FK728_RS03190	COG0318	PFAM AMP-dependent synthetase and ligase
FK728_RS03210	COG0625	glutathione transferase activity
FK728_RS03215	COG1238	metal cluster binding
FK728_RS03255	COG0072	phenylalanine-tRNA ligase activity
FK728_RS03285	COG0248	Ppx GppA phosphatase
FK728_RS03295	COG0037	tRNA processing
FK728_RS03335	COG1764	response to oxidative stress
FK728_RS03340	COG1846	Transcriptional regulator
FK728_RS03350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FK728_RS03410	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FK728_RS03415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FK728_RS03420	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FK728_RS03480	COG1214	PFAM Peptidase M22, glycoprotease
FK728_RS03505	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FK728_RS03510	COG0561	phosphatase activity
FK728_RS03520	COG2132	Multicopper oxidase
FK728_RS03540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FK728_RS03545	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FK728_RS03550	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FK728_RS03580	COG1063	alcohol dehydrogenase
FK728_RS03585	COG0583	DNA-binding transcription factor activity
FK728_RS03590	COG1960	acyl-CoA dehydrogenase activity
FK728_RS03595	COG2814	Major facilitator Superfamily
FK728_RS03600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FK728_RS03610	COG1053	succinate dehydrogenase
FK728_RS03615	COG0583	DNA-binding transcription factor activity
FK728_RS03635	COG0583	DNA-binding transcription factor activity
FK728_RS03665	COG0583	DNA-binding transcription factor activity
FK728_RS03680	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_RS03755	COG0210	DNA helicase
FK728_RS03820	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK728_RS03840	COG0745	RESPONSE REGULATOR receiver
FK728_RS03880	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FK728_RS03910	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FK728_RS03915	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FK728_RS03940	COG0583	DNA-binding transcription factor activity
FK728_RS03960	COG0668	transmembrane transport
FK728_RS03970	COG2081	HI0933 family
FK728_RS03975	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FK728_RS04005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FK728_RS04005	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FK728_RS04015	COG0489	protein tyrosine kinase activity
FK728_RS04075	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FK728_RS04085	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FK728_RS04100	COG0730	response to heat
FK728_RS04110	COG1196	nuclear chromosome segregation
FK728_RS04130	COG2223	nitrite transmembrane transporter activity
FK728_RS04135	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FK728_RS04140	COG1877	trehalose-phosphatase activity
FK728_RS04145	COG2226	methyltransferase
FK728_RS04145	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK728_RS04145	COG0596	Alpha beta hydrolase
FK728_RS04160	COG4106	trans-aconitate 2-methyltransferase activity
FK728_RS04175	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FK728_RS04180	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FK728_RS04185	COG0009	L-threonylcarbamoyladenylate synthase
FK728_RS04190	COG3101	peptidyl-lysine hydroxylation
FK728_RS04195	COG1399	metal-binding, possibly nucleic acid-binding protein
FK728_RS04220	COG1652	LysM domain
FK728_RS04225	COG0352	thiamine-phosphate diphosphorylase activity
FK728_RS04225	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FK728_RS04225	COG0351	phosphomethylpyrimidine kinase
FK728_RS04235	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FK728_RS04265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FK728_RS04295	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FK728_RS04310	COG0358	DNA primase activity
FK728_RS04320	COG0564	pseudouridine synthase activity
FK728_RS04345	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK728_RS04365	COG0583	DNA-binding transcription factor activity
FK728_RS04370	COG0473	3-isopropylmalate dehydrogenase activity
FK728_RS04380	COG0657	acetylesterase activity
FK728_RS04390	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS04410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FK728_RS04410	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FK728_RS04425	COG1981	membrane
FK728_RS04470	COG0456	acetyltransferase
FK728_RS04480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FK728_RS04485	COG0492	ferredoxin-NADP+ reductase activity
FK728_RS04490	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FK728_RS04490	COG1674	ftsk spoiiie
FK728_RS04495	COG1280	lysine exporter protein (LysE YggA)
FK728_RS04510	COG2894	cell division
FK728_RS04525	COG0204	Acyl-transferase
FK728_RS04530	COG2885	chlorophyll binding
FK728_RS04535	COG0210	DNA helicase
FK728_RS04545	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK728_RS04560	COG0121	glutamine amidotransferase
FK728_RS04585	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK728_RS04590	COG0735	belongs to the Fur family
FK728_RS04615	COG0420	3'-5' exonuclease activity
FK728_RS04635	COG1090	epimerase
FK728_RS04650	COG2050	protein possibly involved in aromatic compounds catabolism
FK728_RS04655	COG1566	PFAM secretion protein HlyD family protein
FK728_RS04660	COG2814	Major facilitator Superfamily
FK728_RS04665	COG0405	Gamma-glutamyltransferase
FK728_RS04745	COG0477	Major facilitator Superfamily
FK728_RS04750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FK728_RS04775	COG0531	amino acid
FK728_RS04780	COG2040	homocysteine
FK728_RS04805	COG1309	transcriptional regulator
FK728_RS04810	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK728_RS04815	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK728_RS04825	COG1607	acyl-coa hydrolase
FK728_RS04835	COG0523	cobalamin synthesis protein
FK728_RS04845	COG4681	YaeQ
FK728_RS04855	COG0726	polysaccharide deacetylase
FK728_RS04855	COG1649	PFAM Uncharacterised BCR, COG1649
FK728_RS04860	COG1215	transferase activity, transferring glycosyl groups
FK728_RS04870	COG1024	Enoyl-CoA hydratase
FK728_RS04885	COG1414	Transcriptional regulator
FK728_RS04905	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS04920	COG2271	Major facilitator Superfamily
FK728_RS04930	COG2267	carboxylic ester hydrolase activity
FK728_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS04950	COG0028	Belongs to the TPP enzyme family
FK728_RS04960	COG0477	Major facilitator Superfamily
FK728_RS04965	COG0242	peptide deformylase activity
FK728_RS04970	COG2066	Belongs to the glutaminase family
FK728_RS04975	COG2207	Transcriptional regulator
FK728_RS04980	COG2223	nitrite transmembrane transporter activity
FK728_RS05000	COG0583	DNA-binding transcription factor activity
FK728_RS05005	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS05010	COG2271	Major facilitator Superfamily
FK728_RS05015	COG3959	Transketolase, thiamine diphosphate binding domain
FK728_RS05020	COG3958	Transketolase
FK728_RS05030	COG0306	phosphate transporter
FK728_RS05050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FK728_RS05095	COG4181	ATPase activity
FK728_RS05100	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FK728_RS05130	COG0583	DNA-binding transcription factor activity
FK728_RS05140	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK728_RS05145	COG1773	rubredoxin
FK728_RS05195	COG2851	Citrate transporter
FK728_RS05205	COG1253	flavin adenine dinucleotide binding
FK728_RS05245	COG0804	urea catabolic process
FK728_RS05255	COG0830	nickel cation binding
FK728_RS05270	COG0742	ribosomal rna small subunit methyltransferase
FK728_RS05275	COG0768	penicillin binding
FK728_RS05300	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FK728_RS05305	COG2878	Part of a membrane complex involved in electron transport
FK728_RS05310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FK728_RS05320	COG3384	dioxygenase
FK728_RS05345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FK728_RS05605	COG1598	PFAM Uncharacterised protein family UPF0150
FK728_RS05750	COG0006	proline dipeptidase activity
FK728_RS05755	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_RS05760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_RS05780	COG1279	arginine transmembrane transporter activity
FK728_RS05785	COG0583	DNA-binding transcription factor activity
FK728_RS05825	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK728_RS05830	COG0741	lytic transglycosylase activity
FK728_RS05830	COG1388	LysM domain
FK728_RS05830	COG0741	lytic transglycosylase activity
FK728_RS05830	COG1388	LysM domain
FK728_RS05840	COG4174	ABC transporter (Permease)
FK728_RS05845	COG4239	(ABC) transporter, permease
FK728_RS05850	COG4172	Belongs to the ABC transporter superfamily
FK728_RS05875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK728_RS05885	COG5001	Diguanylate cyclase
FK728_RS05885	COG4251	negative regulation of phosphorylation
FK728_RS05885	COG2203	Gaf domain
FK728_RS05885	COG3706	GGDEF domain
FK728_RS05895	COG0446	pyridine nucleotide-disulphide oxidoreductase
FK728_RS05895	COG1902	pentaerythritol trinitrate reductase activity
FK728_RS05905	COG0582	viral genome integration into host DNA
FK728_RS06010	COG2814	Major facilitator Superfamily
FK728_RS06025	COG1230	cation diffusion facilitator family transporter
FK728_RS06035	COG2015	COG2015, Alkyl sulfatase and related hydrolases
FK728_RS06045	COG2059	Chromate
FK728_RS06100	COG4372	Transposase
FK728_RS06110	COG2963	transposase activity
FK728_RS06125	COG1113	amino acid transport
FK728_RS06135	COG0531	amino acid
FK728_RS06155	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS06175	COG1113	amino acid transport
FK728_RS06190	COG0697	spore germination
FK728_RS06195	COG2721	sulfolactate sulfo-lyase activity
FK728_RS06200	COG2271	Major facilitator Superfamily
FK728_RS06205	COG4948	Mandelate Racemase Muconate Lactonizing
FK728_RS06215	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS06220	COG2186	Transcriptional regulator
FK728_RS06245	COG1960	acyl-CoA dehydrogenase activity
FK728_RS06255	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS06260	COG1024	Enoyl-CoA hydratase
FK728_RS06265	COG2814	Major facilitator Superfamily
FK728_RS06280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK728_RS06295	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FK728_RS06335	COG2207	Transcriptional regulator
FK728_RS06340	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FK728_RS06355	COG0583	DNA-binding transcription factor activity
FK728_RS06360	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FK728_RS06365	COG2072	flavoprotein involved in K transport
FK728_RS06370	COG0300	oxidoreductase activity
FK728_RS06380	COG1309	transcriptional regulator
FK728_RS06385	COG1741	Belongs to the pirin family
FK728_RS06400	COG2072	flavoprotein involved in K transport
FK728_RS06420	COG2252	PERMEase
FK728_RS06425	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FK728_RS06430	COG3038	cytochrome b561
FK728_RS06440	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FK728_RS06450	COG0527	aspartate kinase activity
FK728_RS06460	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FK728_RS06470	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FK728_RS06485	COG0667	Aldo Keto reductase
FK728_RS06495	COG1765	OsmC-like protein
FK728_RS06510	COG0542	response to heat
FK728_RS06545	COG2885	chlorophyll binding
FK728_RS06555	COG0625	glutathione transferase activity
FK728_RS06560	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FK728_RS06580	COG3634	alkyl hydroperoxide reductase activity
FK728_RS06590	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FK728_RS06600	COG0450	alkyl hydroperoxide reductase
FK728_RS06605	COG1643	Atp-dependent helicase
FK728_RS06620	COG2814	Major facilitator Superfamily
FK728_RS06625	COG3135	benzoate transporter
FK728_RS06630	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS06635	COG0633	Ferredoxin
FK728_RS06635	COG0543	2 iron, 2 sulfur cluster binding
FK728_RS06640	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FK728_RS06645	COG4638	Rieske (2fe-2S)
FK728_RS06650	COG0583	DNA-binding transcription factor activity
FK728_RS06705	COG1570	exodeoxyribonuclease VII activity
FK728_RS06740	COG1280	lysine exporter protein (LysE YggA)
FK728_RS06745	COG1278	Cold shock
FK728_RS06785	COG2814	Major facilitator Superfamily
FK728_RS06815	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK728_RS06835	COG0517	IMP dehydrogenase activity
FK728_RS06835	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FK728_RS06840	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FK728_RS06850	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FK728_RS06855	COG1137	ATPase activity
FK728_RS06860	COG1538	Outer membrane efflux protein
FK728_RS06890	COG4122	O-methyltransferase activity
FK728_RS06900	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FK728_RS06915	COG1522	sequence-specific DNA binding
FK728_RS06920	COG5006	permease, DMT superfamily
FK728_RS06930	COG1560	Kdo2-lipid A biosynthetic process
FK728_RS06945	COG2814	Major facilitator Superfamily
FK728_RS06965	COG1250	3-hydroxyacyl-CoA dehydrogenase
FK728_RS06990	COG2801	Transposase and inactivated derivatives
FK728_RS07010	COG0753	catalase activity
FK728_RS07015	COG3038	cytochrome b561
FK728_RS07035	COG2267	carboxylic ester hydrolase activity
FK728_RS07040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_RS07045	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FK728_RS07050	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS07060	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FK728_RS07070	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS07075	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FK728_RS07080	COG0583	DNA-binding transcription factor activity
FK728_RS07090	COG1414	Transcriptional regulator
FK728_RS07095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_RS07105	COG1840	ABC-type Fe3 transport system, periplasmic component
FK728_RS07110	COG3842	ATPase activity
FK728_RS07125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FK728_RS07130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FK728_RS07135	COG2814	Major facilitator Superfamily
FK728_RS07140	COG1960	acyl-CoA dehydrogenase activity
FK728_RS07155	COG1024	Enoyl-CoA hydratase
FK728_RS07165	COG2814	Major facilitator Superfamily
FK728_RS07175	COG0183	Belongs to the thiolase family
FK728_RS07180	COG1250	3-hydroxyacyl-CoA dehydrogenase
FK728_RS07185	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS07190	COG1024	Enoyl-CoA hydratase
FK728_RS07195	COG1960	acyl-CoA dehydrogenase activity
FK728_RS07200	COG2814	Major facilitator Superfamily
FK728_RS07205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FK728_RS07210	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FK728_RS07220	COG2814	Major facilitator Superfamily
FK728_RS07230	COG1960	acyl-CoA dehydrogenase activity
FK728_RS07245	COG0583	DNA-binding transcription factor activity
FK728_RS07255	COG4770	biotin carboxylase activity
FK728_RS07260	COG1024	Enoyl-CoA hydratase
FK728_RS07265	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FK728_RS07270	COG1960	acyl-CoA dehydrogenase activity
FK728_RS07275	COG1309	transcriptional regulator
FK728_RS07280	COG0318	PFAM AMP-dependent synthetase and ligase
FK728_RS07300	COG0583	DNA-binding transcription factor activity
FK728_RS07345	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS07365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FK728_RS07385	COG2205	protein histidine kinase activity
FK728_RS07385	COG0784	Response regulator, receiver
FK728_RS07440	COG0765	amino acid transport
FK728_RS07445	COG0765	amino acid transport
FK728_RS07450	COG1126	abc transporter atp-binding protein
FK728_RS07455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK728_RS07460	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FK728_RS07475	COG1280	lysine exporter protein (LysE YggA)
FK728_RS07480	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FK728_RS07485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FK728_RS07490	COG1045	serine acetyltransferase
FK728_RS07505	COG0583	DNA-binding transcription factor activity
FK728_RS07510	COG0625	glutathione transferase activity
FK728_RS07515	COG0625	glutathione transferase activity
FK728_RS07520	COG0583	DNA-binding transcription factor activity
FK728_RS07530	COG1346	cytolysis
FK728_RS07550	COG2814	Major facilitator Superfamily
FK728_RS07560	COG0583	DNA-binding transcription factor activity
FK728_RS07570	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FK728_RS07575	COG3052	prosthetic group binding
FK728_RS07595	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FK728_RS07615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_RS07625	COG1294	oxidase, subunit
FK728_RS07630	COG1271	oxidase subunit
FK728_RS07655	COG0477	Major facilitator Superfamily
FK728_RS07665	COG4521	taurine ABC transporter
FK728_RS07670	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FK728_RS07675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FK728_RS07680	COG2175	clavaminate synthase activity
FK728_RS07690	COG1953	Uracil, thiamine, allantoin
FK728_RS07700	COG0583	DNA-binding transcription factor activity
FK728_RS07710	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FK728_RS07725	COG0640	Transcriptional regulator
FK728_RS07730	COG0798	PFAM Bile acid sodium symporter
FK728_RS07735	COG0583	DNA-binding transcription factor activity
FK728_RS07750	COG3634	alkyl hydroperoxide reductase activity
FK728_RS07790	COG0436	Aminotransferase
FK728_RS07800	COG0386	Belongs to the glutathione peroxidase family
FK728_RS07815	COG0436	Aminotransferase
FK728_RS07840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FK728_RS07865	COG0012	GTP binding
FK728_RS07870	COG2011	ABC-type metal ion transport system permease component
FK728_RS07875	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FK728_RS07885	COG1464	Belongs to the NlpA lipoprotein family
FK728_RS07915	COG0765	amino acid transport
FK728_RS07920	COG0765	amino acid transport
FK728_RS07925	COG1126	abc transporter atp-binding protein
FK728_RS07935	COG1522	sequence-specific DNA binding
FK728_RS07950	COG1309	transcriptional regulator
FK728_RS07970	COG0583	DNA-binding transcription factor activity
FK728_RS07980	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FK728_RS07990	COG0697	spore germination
FK728_RS08020	COG3121	Chaperone
FK728_RS08025	COG3539	Fimbrial protein
FK728_RS08050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FK728_RS08050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FK728_RS08095	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FK728_RS08105	COG2353	YceI-like domain
FK728_RS08115	COG3698	Phosphodiester glycosidase
FK728_RS08130	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FK728_RS08135	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK728_RS08135	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FK728_RS08135	COG0506	proline dehydrogenase activity
FK728_RS08145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FK728_RS08150	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FK728_RS08170	COG1132	(ABC) transporter
FK728_RS08175	COG3122	Protein conserved in bacteria
FK728_RS08180	COG3619	membrane
FK728_RS08190	COG0640	Transcriptional regulator
FK728_RS08200	COG2850	peptidyl-arginine hydroxylation
FK728_RS08205	COG0424	maF-like protein
FK728_RS08225	COG0191	fructose-bisphosphate aldolase activity
FK728_RS08230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FK728_RS08245	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FK728_RS08255	COG1192	Involved in chromosome partitioning
FK728_RS08260	COG1475	DNA binding
FK728_RS08265	COG0811	peptide transport
FK728_RS08275	COG1132	(ABC) transporter
FK728_RS08280	COG1663	tetraacyldisaccharide 4'-kinase activity
FK728_RS08300	COG0084	hydrolase, TatD family'
FK728_RS08365	COG0776	regulation of translation
FK728_RS08395	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FK728_RS08400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FK728_RS08435	COG4166	transmembrane transport
FK728_RS08445	COG0339	signal peptide processing
FK728_RS08455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FK728_RS08490	COG0702	epimerase
FK728_RS08495	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FK728_RS08515	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FK728_RS08545	COG0316	Belongs to the HesB IscA family
FK728_RS08550	COG0822	iron-sulfur transferase activity
FK728_RS08575	COG0776	regulation of translation
FK728_RS08580	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FK728_RS08585	COG2207	Transcriptional regulator
FK728_RS08590	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK728_RS08595	COG1960	acyl-CoA dehydrogenase activity
FK728_RS08600	COG1960	acyl-CoA dehydrogenase activity
FK728_RS08615	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FK728_RS08630	COG2814	Major facilitator Superfamily
FK728_RS08635	COG4264	IucA IucC family
FK728_RS08640	COG4264	IucA IucC family
FK728_RS08650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FK728_RS08700	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FK728_RS08705	COG0406	alpha-ribazole phosphatase activity
FK728_RS08720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FK728_RS08725	COG0730	response to heat
FK728_RS08745	COG4773	Receptor
FK728_RS08750	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FK728_RS08765	COG1131	(ABC) transporter
FK728_RS08770	COG0842	Transport permease protein
FK728_RS08775	COG0842	Transport permease protein
FK728_RS08830	COG2226	methyltransferase
FK728_RS08855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FK728_RS08900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FK728_RS08910	COG0133	tryptophan synthase activity
FK728_RS08925	COG3706	GGDEF domain
FK728_RS08940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FK728_RS08950	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FK728_RS08955	COG0022	dehydrogenase e1 component
FK728_RS08960	COG0508	dehydrogenase complex catalyzes the overall conversion of
FK728_RS08965	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK728_RS08975	COG1063	alcohol dehydrogenase
FK728_RS08980	COG3781	membrane
FK728_RS08990	COG3453	Protein conserved in bacteria
FK728_RS08990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK728_RS09000	COG0730	response to heat
FK728_RS09015	COG2207	Transcriptional regulator
FK728_RS09015	COG3708	Transcriptional regulator
FK728_RS09020	COG1733	regulation of RNA biosynthetic process
FK728_RS09025	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FK728_RS09035	COG2188	Transcriptional regulator
FK728_RS09050	COG4521	taurine ABC transporter
FK728_RS09075	COG0477	Major facilitator Superfamily
FK728_RS09085	COG1027	Aspartate ammonia-lyase
FK728_RS09100	COG0583	DNA-binding transcription factor activity
FK728_RS09105	COG0583	DNA-binding transcription factor activity
FK728_RS09110	COG0183	Belongs to the thiolase family
FK728_RS09115	COG2031	fatty acid transporter
FK728_RS09130	COG0583	DNA-binding transcription factor activity
FK728_RS09150	COG1309	transcriptional regulator
FK728_RS09160	COG2610	gluconate transmembrane transporter activity
FK728_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS09170	COG2207	Transcriptional regulator
FK728_RS09185	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS09195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_RS09210	COG0543	2 iron, 2 sulfur cluster binding
FK728_RS09210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK728_RS09215	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FK728_RS09220	COG4638	Rieske (2fe-2S)
FK728_RS09230	COG0725	ABC transporter, periplasmic molybdate-binding protein
FK728_RS09235	COG4149	molybdate abc transporter
FK728_RS09240	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FK728_RS09245	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS09250	COG1535	isochorismatase
FK728_RS09250	COG3433	isochorismatase activity
FK728_RS09315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK728_RS09330	COG0753	catalase activity
FK728_RS09340	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FK728_RS09365	COG3539	Fimbrial protein
FK728_RS09385	COG2072	flavoprotein involved in K transport
FK728_RS09400	COG2205	protein histidine kinase activity
FK728_RS09405	COG0745	RESPONSE REGULATOR receiver
FK728_RS09410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_RS09415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FK728_RS09445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FK728_RS09455	COG1073	alpha beta
FK728_RS09520	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FK728_RS09615	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FK728_RS09635	COG1120	ATPase activity
FK728_RS09640	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FK728_RS09650	COG1064	alcohol dehydrogenase
FK728_RS09655	COG2207	Transcriptional regulator
FK728_RS09660	COG2084	Dehydrogenase
FK728_RS09670	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FK728_RS09675	COG0583	DNA-binding transcription factor activity
FK728_RS09685	COG0129	dihydroxy-acid dehydratase activity
FK728_RS09690	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS09705	COG1566	PFAM secretion protein HlyD family protein
FK728_RS09715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FK728_RS09745	COG0583	DNA-binding transcription factor activity
FK728_RS09760	COG2188	Transcriptional regulator
FK728_RS09810	COG1309	transcriptional regulator
FK728_RS09825	COG1522	sequence-specific DNA binding
FK728_RS09830	COG0814	amino acid
FK728_RS09835	COG1473	amidohydrolase
FK728_RS09840	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FK728_RS09845	COG0251	oxidation-reduction process
FK728_RS09850	COG1309	transcriptional regulator
FK728_RS09875	COG0789	Transcriptional regulator
FK728_RS09885	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FK728_RS09910	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS09930	COG2186	Transcriptional regulator
FK728_RS09940	COG0583	DNA-binding transcription factor activity
FK728_RS09945	COG4948	Mandelate Racemase Muconate Lactonizing
FK728_RS09950	COG4829	muconolactone delta-isomerase
FK728_RS09960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FK728_RS09965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FK728_RS09970	COG0183	Belongs to the thiolase family
FK728_RS09975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FK728_RS09985	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS09995	COG3733	amine oxidase
FK728_RS10005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_RS10015	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS10025	COG4638	Rieske (2fe-2S)
FK728_RS10045	COG0154	amidase activity
FK728_RS10080	COG1960	acyl-CoA dehydrogenase activity
FK728_RS10085	COG0583	DNA-binding transcription factor activity
FK728_RS10090	COG1414	Transcriptional regulator
FK728_RS10105	COG2391	methyltransferase activity
FK728_RS10130	COG3659	wide pore channel activity
FK728_RS10135	COG3420	alginic acid biosynthetic process
FK728_RS10140	COG0710	3-dehydroquinate dehydratase activity
FK728_RS10145	COG3485	protocatechuate 3,4-dioxygenase
FK728_RS10150	COG3485	protocatechuate 3,4-dioxygenase
FK728_RS10155	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FK728_RS10160	COG2271	Major facilitator Superfamily
FK728_RS10165	COG0596	Alpha beta hydrolase
FK728_RS10170	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FK728_RS10175	COG0183	Belongs to the thiolase family
FK728_RS10180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FK728_RS10185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FK728_RS10195	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FK728_RS10205	COG2323	membrane
FK728_RS10250	COG0446	pyridine nucleotide-disulphide oxidoreductase
FK728_RS10250	COG1902	pentaerythritol trinitrate reductase activity
FK728_RS10275	COG0542	response to heat
FK728_RS10280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FK728_RS10310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FK728_RS10315	COG0569	domain protein
FK728_RS10320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FK728_RS10335	COG4774	siderophore transport
FK728_RS10340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FK728_RS10350	COG1585	Membrane protein implicated in regulation of membrane protease activity
FK728_RS10365	COG1294	oxidase, subunit
FK728_RS10370	COG4890	Cyd operon protein YbgT
FK728_RS10385	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FK728_RS10395	COG0552	protein localization to endoplasmic reticulum
FK728_RS10420	COG0517	IMP dehydrogenase activity
FK728_RS10420	COG0516	GMP reductase activity
FK728_RS10425	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FK728_RS10430	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FK728_RS10440	COG0583	DNA-binding transcription factor activity
FK728_RS10445	COG0024	Methionine aminopeptidase
FK728_RS10475	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FK728_RS10475	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FK728_RS10480	COG1105	Belongs to the carbohydrate kinase PfkB family
FK728_RS10485	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK728_RS10485	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FK728_RS10485	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FK728_RS10500	COG5001	Diguanylate cyclase
FK728_RS10500	COG3300	MHYT domain
FK728_RS10515	COG2135	peptidase activity
FK728_RS10520	COG0659	secondary active sulfate transmembrane transporter activity
FK728_RS10535	COG1113	amino acid transport
FK728_RS10545	COG1522	sequence-specific DNA binding
FK728_RS10580	COG1011	Hydrolase
FK728_RS10585	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FK728_RS10595	COG2137	regulation of response to DNA damage stimulus
FK728_RS10610	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FK728_RS10630	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FK728_RS10645	COG0575	Belongs to the CDS family
FK728_RS10650	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FK728_RS10675	COG3852	Histidine kinase
FK728_RS10680	COG2204	response regulator
FK728_RS10685	COG1309	transcriptional regulator
FK728_RS10740	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FK728_RS10745	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FK728_RS10765	COG0697	spore germination
FK728_RS10770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_RS10780	COG0303	'Molybdopterin
FK728_RS10785	COG0521	Mo-molybdopterin cofactor biosynthetic process
FK728_RS10785	COG0315	cyclic pyranopterin monophosphate synthase activity
FK728_RS10800	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FK728_RS10805	COG0243	molybdopterin cofactor binding
FK728_RS10815	COG0243	molybdopterin cofactor binding
FK728_RS10820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK728_RS10825	COG2146	nitrite reductase [NAD(P)H] activity
FK728_RS10825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK728_RS10835	COG0745	RESPONSE REGULATOR receiver
FK728_RS10840	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FK728_RS10840	COG1116	anion transmembrane transporter activity
FK728_RS10855	COG0511	ligase activity, forming carbon-carbon bonds
FK728_RS10870	COG2814	Major facilitator Superfamily
FK728_RS10890	COG0069	glutamate synthase activity
FK728_RS10910	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FK728_RS10920	COG1454	alcohol dehydrogenase
FK728_RS10925	COG0824	Thioesterase
FK728_RS10935	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FK728_RS10960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FK728_RS10965	COG2030	dehydratase
FK728_RS10970	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS10975	COG0183	Belongs to the thiolase family
FK728_RS10985	COG0583	DNA-binding transcription factor activity
FK728_RS10990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FK728_RS11000	COG1522	sequence-specific DNA binding
FK728_RS11005	COG3135	benzoate transporter
FK728_RS11015	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FK728_RS11030	COG0589	response to stress
FK728_RS11035	COG0488	(ABC) transporter
FK728_RS11055	COG4773	Receptor
FK728_RS11085	COG0668	transmembrane transport
FK728_RS11095	COG1309	transcriptional regulator
FK728_RS11105	COG2801	Transposase and inactivated derivatives
FK728_RS11120	COG1605	Chorismate mutase
FK728_RS11160	COG0308	aminopeptidase N
FK728_RS11185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FK728_RS11190	COG1454	alcohol dehydrogenase
FK728_RS11210	COG0531	amino acid
FK728_RS11215	COG4303	Ethanolamine ammonia lyase large subunit
FK728_RS11220	COG4302	ethanolamine ammonia-lyase activity
FK728_RS11225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FK728_RS11225	COG0519	Catalyzes the synthesis of GMP from XMP
FK728_RS11230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FK728_RS11255	COG0697	spore germination
FK728_RS11260	COG1923	regulation of RNA biosynthetic process
FK728_RS11270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FK728_RS11275	COG0802	atpase or kinase
FK728_RS11295	COG1187	pseudouridine synthase activity
FK728_RS11310	COG0583	DNA-binding transcription factor activity
FK728_RS11325	COG2814	Major facilitator Superfamily
FK728_RS11330	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FK728_RS11340	COG0471	metal ion transport
FK728_RS11380	COG0729	surface antigen
FK728_RS11400	COG0174	glutamine synthetase
FK728_RS11405	COG0745	RESPONSE REGULATOR receiver
FK728_RS11410	COG2205	protein histidine kinase activity
FK728_RS11420	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FK728_RS11425	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FK728_RS11450	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_RS11455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK728_RS11460	COG1960	acyl-CoA dehydrogenase activity
FK728_RS11490	COG0583	DNA-binding transcription factor activity
FK728_RS11510	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FK728_RS11520	COG3658	cytochrome
FK728_RS11525	COG1215	transferase activity, transferring glycosyl groups
FK728_RS11530	COG1649	PFAM Uncharacterised BCR, COG1649
FK728_RS11530	COG0726	polysaccharide deacetylase
FK728_RS11565	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FK728_RS11570	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FK728_RS11580	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FK728_RS11605	COG0305	Participates in initiation and elongation during chromosome replication
FK728_RS11610	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FK728_RS11620	COG1305	Transglutaminase-like
FK728_RS11630	COG2308	Evidence 4 Homologs of previously reported genes of
FK728_RS11660	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FK728_RS11665	COG0138	bifunctional purine biosynthesis protein purh
FK728_RS11670	COG0151	Belongs to the GarS family
FK728_RS11675	COG1464	Belongs to the NlpA lipoprotein family
FK728_RS11680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FK728_RS11685	COG2011	ABC-type metal ion transport system permease component
FK728_RS11690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK728_RS11700	COG1301	dicarboxylic acid transport
FK728_RS11730	COG1794	racemase activity, acting on amino acids and derivatives
FK728_RS11750	COG0745	RESPONSE REGULATOR receiver
FK728_RS11755	COG0642	Histidine kinase
FK728_RS11760	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FK728_RS11770	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FK728_RS11810	COG2351	hydroxyisourate hydrolase activity
FK728_RS11820	COG3008	intermembrane lipid transfer
FK728_RS11820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FK728_RS11825	COG2995	paraquat-inducible protein a
FK728_RS11835	COG2985	domain, Protein
FK728_RS11870	COG1051	belongs to the nudix hydrolase family
FK728_RS11875	COG0477	Major facilitator Superfamily
FK728_RS11925	COG2186	Transcriptional regulator
FK728_RS11935	COG0786	glutamate:sodium symporter activity
FK728_RS11940	COG3243	poly(R)-hydroxyalkanoic acid synthase
FK728_RS11965	COG3111	PFAM Bacterial OB fold (BOF) protein
FK728_RS12035	COG3210	domain, Protein
FK728_RS12055	COG2831	hemolysin activation secretion protein
FK728_RS12080	COG2815	serine threonine protein kinase
FK728_RS12080	COG0515	serine threonine protein kinase
FK728_RS12110	COG1610	YqeY-like protein
FK728_RS12115	COG4783	chaperone-mediated protein folding
FK728_RS12140	COG1286	toxin biosynthetic process
FK728_RS12170	COG0778	Nitroreductase
FK728_RS12180	COG0513	Belongs to the DEAD box helicase family
FK728_RS12200	COG2363	Small membrane protein
FK728_RS12230	COG1234	tRNA 3'-trailer cleavage
FK728_RS12235	COG2195	Cleaves the N-terminal amino acid of tripeptides
FK728_RS12245	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FK728_RS12255	COG2819	hydrolase of the alpha beta superfamily
FK728_RS12260	COG1960	acyl-CoA dehydrogenase activity
FK728_RS12265	COG1301	dicarboxylic acid transport
FK728_RS12275	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FK728_RS12280	COG3139	Protein of unknown function (DUF1315)
FK728_RS12285	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FK728_RS12290	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FK728_RS12300	COG0494	nUDIX hydrolase
FK728_RS12310	COG0642	Histidine kinase
FK728_RS12325	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FK728_RS12335	COG1720	tRNA m6t6A37 methyltransferase activity
FK728_RS12350	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_RS12355	COG0826	peptidase U32
FK728_RS12360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FK728_RS12370	COG4598	ABC transporter
FK728_RS12375	COG4160	amino acid transport
FK728_RS12380	COG4215	(ABC) transporter
FK728_RS12395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_RS12440	COG1131	(ABC) transporter
FK728_RS12445	COG0842	Transport permease protein
FK728_RS12460	COG0772	Belongs to the SEDS family
FK728_RS12465	COG2951	lytic endotransglycosylase activity
FK728_RS12505	COG0052	Belongs to the universal ribosomal protein uS2 family
FK728_RS12510	COG0024	Methionine aminopeptidase
FK728_RS12520	COG2223	nitrite transmembrane transporter activity
FK728_RS12530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK728_RS12535	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FK728_RS12540	COG1960	acyl-CoA dehydrogenase activity
FK728_RS12555	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FK728_RS12560	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FK728_RS12565	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FK728_RS12585	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FK728_RS12590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FK728_RS12595	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FK728_RS12630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FK728_RS12640	COG0174	glutamine synthetase
FK728_RS12655	COG0512	Glutamine amidotransferase of anthranilate synthase
FK728_RS12660	COG0308	aminopeptidase N
FK728_RS12690	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FK728_RS12700	COG0302	gtp cyclohydrolase
FK728_RS12720	COG3739	integral membrane protein
FK728_RS12745	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FK728_RS12750	COG1132	(ABC) transporter
FK728_RS12755	COG1132	(ABC) transporter
FK728_RS12770	COG3433	isochorismatase activity
FK728_RS12770	COG1535	isochorismatase
FK728_RS12775	COG1021	2,3-dihydroxybenzoate-AMP ligase
FK728_RS12780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK728_RS12790	COG4774	siderophore transport
FK728_RS12795	COG4607	ABC-type enterochelin transport system periplasmic component
FK728_RS12800	COG4604	ABC transporter, ATP-binding protein
FK728_RS12805	COG4605	iron ion homeostasis
FK728_RS12810	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FK728_RS12815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK728_RS12830	COG2964	Protein conserved in bacteria
FK728_RS12840	COG1741	Belongs to the pirin family
FK728_RS12870	COG2879	small protein
FK728_RS12875	COG1966	Carbon starvation protein
FK728_RS12895	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FK728_RS12915	COG2211	Major facilitator Superfamily
FK728_RS12920	COG1067	ATP-dependent peptidase activity
FK728_RS12925	COG0583	DNA-binding transcription factor activity
FK728_RS12950	COG1686	Belongs to the peptidase S11 family
FK728_RS12955	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FK728_RS12990	COG0616	signal peptide processing
FK728_RS12995	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FK728_RS13005	COG0573	inorganic phosphate transmembrane transporter activity
FK728_RS13010	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FK728_RS13015	COG1113	amino acid transport
FK728_RS13020	COG3961	Belongs to the TPP enzyme family
FK728_RS13025	COG1522	sequence-specific DNA binding
FK728_RS13035	COG0076	glutamate decarboxylase activity
FK728_RS13040	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FK728_RS13055	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK728_RS13065	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK728_RS13100	COG0352	thiamine-phosphate diphosphorylase activity
FK728_RS13125	COG0612	Peptidase, M16
FK728_RS13135	COG1823	symporter activity
FK728_RS13140	COG0583	DNA-binding transcription factor activity
FK728_RS13145	COG0477	Major facilitator Superfamily
FK728_RS13170	COG1187	pseudouridine synthase activity
FK728_RS13185	COG1686	Belongs to the peptidase S11 family
FK728_RS13190	COG1252	NADH dehydrogenase
FK728_RS13200	COG0415	Belongs to the DNA photolyase family
FK728_RS13215	COG1215	transferase activity, transferring glycosyl groups
FK728_RS13245	COG2070	2-Nitropropane dioxygenase
FK728_RS13300	COG0556	nucleotide-excision repair
FK728_RS13320	COG0436	Aminotransferase
FK728_RS13350	COG4221	oxidoreductase activity
FK728_RS13360	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FK728_RS13365	COG1381	Involved in DNA repair and RecF pathway recombination
FK728_RS13375	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FK728_RS13390	COG0681	Belongs to the peptidase S26 family
FK728_RS13405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FK728_RS13425	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FK728_RS13430	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FK728_RS13435	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FK728_RS13445	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FK728_RS13450	COG4208	sulfate ABC transporter
FK728_RS13455	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FK728_RS13460	COG0583	DNA-binding transcription factor activity
FK728_RS13465	COG4625	pathogenesis
FK728_RS13480	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FK728_RS13495	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FK728_RS13505	COG1051	belongs to the nudix hydrolase family
FK728_RS13505	COG1056	cytidyltransferase-related domain
FK728_RS13510	COG1024	Enoyl-CoA hydratase
FK728_RS13520	COG2814	Major facilitator Superfamily
FK728_RS13525	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FK728_RS13525	COG0047	phosphoribosylformylglycinamidine synthase activity
FK728_RS13555	COG1473	amidohydrolase
FK728_RS13560	COG0824	Thioesterase
FK728_RS13580	COG0823	Involved in the tonB-independent uptake of proteins
FK728_RS13600	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FK728_RS13635	COG0628	permease
FK728_RS13645	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FK728_RS13650	COG0596	Alpha beta hydrolase
FK728_RS13655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FK728_RS13655	COG0616	signal peptide processing
FK728_RS13665	COG0658	competence protein
FK728_RS13665	COG2333	competence protein COMEC
FK728_RS13670	COG1136	(ABC) transporter
FK728_RS13675	COG4591	ABC-type transport system involved in lipoprotein release permease component
FK728_RS13705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_RS13725	COG0463	Glycosyl transferase, family 2
FK728_RS13755	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FK728_RS13760	COG1280	lysine exporter protein (LysE YggA)
FK728_RS13770	COG0019	diaminopimelate decarboxylase activity
FK728_RS13780	COG1113	amino acid transport
FK728_RS13795	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FK728_RS13805	COG3339	Conserved Protein
FK728_RS13810	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FK728_RS13815	COG0243	molybdopterin cofactor binding
FK728_RS13820	COG1929	Belongs to the glycerate kinase type-1 family
FK728_RS13835	COG0778	Nitroreductase
FK728_RS13860	COG2801	Transposase and inactivated derivatives
FK728_RS13885	COG3811	Belongs to the UPF0386 family
FK728_RS13925	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK728_RS13940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FK728_RS13965	COG0741	lytic transglycosylase activity
FK728_RS13985	COG0584	glycerophosphoryl diester phosphodiesterase
FK728_RS13990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FK728_RS14010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FK728_RS14015	COG1597	lipid kinase activity
FK728_RS14030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FK728_RS14035	COG0477	Major facilitator Superfamily
FK728_RS14085	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FK728_RS14090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FK728_RS14115	COG0505	Belongs to the CarA family
FK728_RS14130	COG1309	transcriptional regulator
FK728_RS14135	COG0251	oxidation-reduction process
FK728_RS14145	COG0589	response to stress
FK728_RS14160	COG2843	Capsule synthesis protein
FK728_RS14190	COG2321	neutral zinc metallopeptidase
FK728_RS14195	COG2354	Protein conserved in bacteria
FK728_RS14215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FK728_RS14240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FK728_RS14245	COG1053	succinate dehydrogenase
FK728_RS14250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FK728_RS14255	COG2009	succinate dehydrogenase
FK728_RS14290	COG2921	Belongs to the UPF0250 family
FK728_RS14295	COG0321	lipoyl(octanoyl) transferase activity
FK728_RS14310	COG0531	amino acid
FK728_RS14320	COG1733	regulation of RNA biosynthetic process
FK728_RS14325	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FK728_RS14330	COG1648	precorrin-2 dehydrogenase activity
FK728_RS14330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FK728_RS14345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FK728_RS14375	COG0671	phosphoesterase, PA-phosphatase related
FK728_RS14380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_RS14390	COG1538	Outer membrane efflux protein
FK728_RS14395	COG0393	Putative heavy-metal-binding
FK728_RS14400	COG0393	Putative heavy-metal-binding
FK728_RS14410	COG1028	Short-chain dehydrogenase reductase Sdr
FK728_RS14420	COG0525	valine-tRNA ligase activity
FK728_RS14445	COG0583	DNA-binding transcription factor activity
FK728_RS14465	COG0642	Histidine kinase
FK728_RS14470	COG0745	RESPONSE REGULATOR receiver
FK728_RS14475	COG2194	sulfuric ester hydrolase activity
FK728_RS14495	COG1752	Esterase of the alpha-beta hydrolase superfamily
FK728_RS14510	COG2315	Protein conserved in bacteria
FK728_RS14515	COG0142	geranyltranstransferase activity
FK728_RS14520	COG2828	Protein conserved in bacteria
FK728_RS14525	COG1113	amino acid transport
FK728_RS14535	COG0582	viral genome integration into host DNA
FK728_RS14570	COG0305	Participates in initiation and elongation during chromosome replication
FK728_RS14620	COG0464	growth
FK728_RS14640	COG2207	Transcriptional regulator
FK728_RS14665	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK728_RS14675	COG0560	Phosphoserine phosphatase
FK728_RS14685	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FK728_RS14695	COG1530	ribonuclease E activity
FK728_RS14700	COG0424	maF-like protein
FK728_RS14705	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FK728_RS14710	COG1792	Involved in formation and maintenance of cell shape
FK728_RS14715	COG1077	Cell shape determining protein MreB Mrl
FK728_RS14720	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FK728_RS14730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FK728_RS14760	COG3590	peptidase
FK728_RS14765	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FK728_RS14770	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FK728_RS14775	COG1752	Esterase of the alpha-beta hydrolase superfamily
FK728_RS14780	COG1115	amino acid carrier protein
FK728_RS14805	COG2814	Major facilitator Superfamily
FK728_RS14810	COG1289	transmembrane transporter activity
FK728_RS14820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FK728_RS14860	COG1376	ErfK ybiS ycfS ynhG family protein
FK728_RS14865	COG2832	Protein of unknown function (DUF454)
FK728_RS14875	COG5510	response to toxic substance
FK728_RS14895	COG0840	transmembrane signaling receptor activity
FK728_RS14935	COG3422	double-strand break repair
FK728_RS14940	COG2824	Alkylphosphonate utilization operon protein PhnA
FK728_RS14945	COG3189	MarR family transcriptional regulator
FK728_RS14955	COG0354	folic acid binding
FK728_RS14960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FK728_RS14975	COG1902	pentaerythritol trinitrate reductase activity
FK728_RS14980	COG4772	TonB-dependent receptor
FK728_RS14985	COG2094	Belongs to the DNA glycosylase MPG family
FK728_RS15010	COG1217	gtp-binding protein TYPA
FK728_RS15015	COG2233	PERMEase
FK728_RS15025	COG0833	amino acid
FK728_RS15030	COG1690	Belongs to the RtcB family
FK728_RS15035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FK728_RS15035	COG2885	chlorophyll binding
FK728_RS15045	COG0183	Belongs to the thiolase family
FK728_RS15065	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FK728_RS15085	COG2207	Transcriptional regulator
FK728_RS15090	COG0183	Belongs to the thiolase family
FK728_RS15120	COG1272	protein, Hemolysin III
FK728_RS15125	COG0477	Major facilitator Superfamily
FK728_RS15140	COG0450	alkyl hydroperoxide reductase
FK728_RS15160	COG0285	dihydrofolate synthase activity
FK728_RS15205	COG4206	TonB-dependent receptor
FK728_RS15210	COG2096	Adenosyltransferase
FK728_RS15230	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FK728_RS15235	COG0745	RESPONSE REGULATOR receiver
FK728_RS15240	COG2205	protein histidine kinase activity
FK728_RS15250	COG1960	acyl-CoA dehydrogenase activity
FK728_RS15255	COG1960	acyl-CoA dehydrogenase activity
FK728_RS15325	COG0438	transferase activity, transferring glycosyl groups
FK728_RS15330	COG0726	polysaccharide deacetylase
FK728_RS15345	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FK728_RS15350	COG2205	protein histidine kinase activity
FK728_RS15385	COG1862	Preprotein translocase
FK728_RS15395	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FK728_RS15400	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FK728_RS15410	COG3781	membrane
FK728_RS15415	COG0613	PHP domain protein
FK728_RS15425	COG2350	Protein conserved in bacteria
FK728_RS15455	COG1607	acyl-coa hydrolase
FK728_RS15515	COG2199	diguanylate cyclase activity
FK728_RS15525	COG1408	metallophosphoesterase
FK728_RS15530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FK728_RS15540	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FK728_RS15560	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FK728_RS15565	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FK728_RS15570	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FK728_RS15580	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FK728_RS15590	COG2969	positive regulation of protein catabolic process
FK728_RS15610	COG1960	acyl-CoA dehydrogenase activity
FK728_RS15615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FK728_RS15630	COG1309	transcriptional regulator
FK728_RS15635	COG1960	acyl-CoA dehydrogenase activity
FK728_RS15680	COG1183	phosphatidylcholine synthase activity
FK728_RS15685	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FK728_RS15715	COG0739	heme binding
FK728_RS15715	COG1196	nuclear chromosome segregation
FK728_RS15715	COG0741	lytic transglycosylase activity
FK728_RS15725	COG1702	phosphate starvation-inducible protein PhoH
FK728_RS15760	COG1295	ribonuclease BN
FK728_RS15765	COG0697	spore germination
FK728_RS15770	COG2169	Transcriptional regulator
FK728_RS15775	COG0179	Fumarylacetoacetate (FAA) hydrolase
FK728_RS15820	COG0557	exoribonuclease II activity
FK728_RS15825	COG0339	signal peptide processing
FK728_RS15830	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FK728_RS15860	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FK728_RS15865	COG1960	acyl-CoA dehydrogenase activity
FK728_RS16020	COG0626	cystathionine gamma-synthase activity
FK728_RS16025	COG0433	COG0433 Predicted ATPase
FK728_RS16035	COG1017	nitric oxide dioxygenase activity
FK728_RS16035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FK728_RS16040	COG1959	2 iron, 2 sulfur cluster binding
FK728_RS16055	COG1301	dicarboxylic acid transport
FK728_RS16060	COG1946	Acyl-CoA thioesterase
FK728_RS16080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FK728_RS16085	COG1040	competence protein
FK728_RS16090	COG0494	nUDIX hydrolase
FK728_RS16100	COG0598	Magnesium transport protein CorA
FK728_RS16110	COG2854	intermembrane phospholipid transfer
FK728_RS16120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FK728_RS16125	COG1127	ABC transporter
FK728_RS16135	COG0513	Belongs to the DEAD box helicase family
FK728_RS16155	COG0408	coproporphyrinogen oxidase activity
FK728_RS16170	COG1960	acyl-CoA dehydrogenase activity
FK728_RS16180	COG1983	PspC domain protein
FK728_RS16185	COG0517	IMP dehydrogenase activity
FK728_RS16240	COG0583	DNA-binding transcription factor activity
FK728_RS16280	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS16290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FK728_RS16295	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FK728_RS16300	COG0833	amino acid
FK728_RS16330	COG1192	Involved in chromosome partitioning
FK728_RS16335	COG0628	permease
FK728_RS16345	COG1289	transmembrane transporter activity
FK728_RS16360	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK728_RS16365	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FK728_RS16375	COG0277	FAD linked oxidase domain protein
FK728_RS16380	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FK728_RS16405	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FK728_RS16410	COG5380	lipid catabolic process
FK728_RS16430	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FK728_RS16480	COG0194	GDP metabolic process
FK728_RS16495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FK728_RS16515	COG3307	-O-antigen
FK728_RS16535	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FK728_RS16540	COG1704	LemA family
FK728_RS16550	COG0493	'glutamate synthase
FK728_RS16555	COG0070	glutamate synthase
FK728_RS16555	COG0069	glutamate synthase activity
FK728_RS16555	COG0067	glutamate synthase
FK728_RS16605	COG2226	methyltransferase
FK728_RS16620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FK728_RS16625	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FK728_RS16670	COG0833	amino acid
FK728_RS16755	COG0488	(ABC) transporter
FK728_RS16760	COG2873	o-acetylhomoserine
FK728_RS16765	COG4221	oxidoreductase activity
FK728_RS16770	COG0659	secondary active sulfate transmembrane transporter activity
FK728_RS16800	COG0427	acetyl-CoA hydrolase
FK728_RS16830	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FK728_RS16850	COG1132	(ABC) transporter
FK728_RS16865	COG2329	Antibiotic biosynthesis monooxygenase
FK728_RS16880	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FK728_RS16950	COG2249	NAD(P)H dehydrogenase (quinone) activity
FK728_RS16955	COG1733	regulation of RNA biosynthetic process
FK728_RS16985	COG1733	regulation of RNA biosynthetic process
FK728_RS17005	COG2801	Transposase and inactivated derivatives
FK728_RS17020	COG0667	Aldo Keto reductase
FK728_RS17040	COG0583	DNA-binding transcription factor activity
FK728_RS17045	COG2814	Major facilitator Superfamily
FK728_RS17080	COG1335	isochorismatase
FK728_RS17090	COG1012	belongs to the aldehyde dehydrogenase family
FK728_RS17095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FK728_RS17105	COG1113	amino acid transport
FK728_RS17115	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FK728_RS17130	COG2814	Major facilitator Superfamily
FK728_RS17140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FK728_RS17140	COG0352	thiamine-phosphate diphosphorylase activity
FK728_RS17140	COG0351	phosphomethylpyrimidine kinase
FK728_RS17160	COG1309	transcriptional regulator
FK728_RS17165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FK728_RS17180	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FK728_RS17190	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FK728_RS17195	COG3162	membrane
FK728_RS17200	COG2205	protein histidine kinase activity
FK728_RS17200	COG2198	Histidine kinase
FK728_RS17200	COG0784	Response regulator, receiver
FK728_RS17225	COG1522	sequence-specific DNA binding
FK728_RS17230	COG1335	isochorismatase
FK728_RS17235	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FK728_RS17250	COG0668	transmembrane transport
FK728_RS17255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FK728_RS17260	COG1519	Transferase
FK728_RS17265	COG1902	pentaerythritol trinitrate reductase activity
FK728_RS17285	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FK728_RS17310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FK728_RS17310	COG0426	domain, Protein
FK728_RS17315	COG4774	siderophore transport
FK728_RS17320	COG2119	membrane
FK728_RS17330	COG0508	dehydrogenase complex catalyzes the overall conversion of
FK728_RS17340	COG4942	peptidase
FK728_RS17355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FK728_RS17365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FK728_RS17385	COG0189	ligase activity
FK728_RS17405	COG0708	Exodeoxyribonuclease III
FK728_RS17410	COG1393	Belongs to the ArsC family
FK728_RS17425	COG3706	GGDEF domain
FK728_RS17460	COG2351	hydroxyisourate hydrolase activity
FK728_RS17465	COG2233	PERMEase
FK728_RS17475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FK728_RS17485	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FK728_RS17495	COG3150	esterase
FK728_RS17530	COG1705	Flagellar rod assembly protein muramidase FlgJ
FK728_RS17530	COG1388	LysM domain
FK728_RS17545	COG2918	glutathione biosynthetic process
FK728_RS17560	COG2733	membrane
FK728_RS17565	COG0436	Aminotransferase
FK728_RS17570	COG0534	Mate efflux family protein
FK728_RS17660	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FK728_RS17665	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FK728_RS17675	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FK728_RS17680	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FK728_RS17695	COG0010	Belongs to the arginase family
FK728_RS17725	COG2188	Transcriptional regulator
FK728_RS17735	COG0523	cobalamin synthesis protein
FK728_RS17745	COG1113	amino acid transport
FK728_RS17755	COG0625	glutathione transferase activity
FK728_RS17775	COG1683	Conserved Protein
FK728_RS17780	COG0534	Mate efflux family protein
FK728_RS17785	COG0385	Bile acid
FK728_RS17790	COG1335	isochorismatase
FK728_RS17795	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FK728_RS17815	COG2116	formate transmembrane transporter activity
FK728_RS17820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FK728_RS17825	COG2133	pyrroloquinoline quinone binding
FK728_RS17830	COG2983	Belongs to the UPF0260 family
FK728_RS17840	COG0400	carboxylic ester hydrolase activity
FK728_RS17850	COG1194	a g-specific adenine glycosylase
FK728_RS17865	COG2818	Glycosylase
FK728_RS17870	COG1064	alcohol dehydrogenase
FK728_RS17875	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FK728_RS17890	COG0583	DNA-binding transcription factor activity
FK728_RS17895	COG0656	L-ascorbic acid biosynthetic process
FK728_RS17900	COG2814	Major facilitator Superfamily
FK728_RS17935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FK728_RS17950	COG2233	PERMEase
FK728_RS17955	COG0583	DNA-binding transcription factor activity
FK728_RS17980	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FK728_RS17990	COG0733	neurotransmitter:sodium symporter activity
FK728_RS18000	COG0625	glutathione transferase activity
FK728_RS18095	COG2826	transposase and inactivated derivatives, IS30 family
FK728_RS18140	COG0358	DNA primase activity
FK728_RS18200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FK728_RS18255	COG0587	DNA-directed DNA polymerase activity
FK728_RS18270	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FK728_RS18270	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
FK728_RS18325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK728_RS18325	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FK728_RS18330	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FK728_RS18385	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FK728_RS18410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FK728_RS18465	COG3586	endonuclease activity
FK728_RS18540	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FK728_RS18585	COG0583	DNA-binding transcription factor activity
FK728_RS18620	COG3173	Aminoglycoside phosphotransferase
FK728_RS18625	COG0488	(ABC) transporter
FK728_RS18660	COG2963	transposase activity
FK728_RS18670	COG4372	Transposase
FK728_RS18725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FK728_RS18745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system