locus-tag	class	description
F3P16_RS00010	COG0592	DNA-directed DNA polymerase activity
F3P16_RS00020	COG0187	DNA topoisomerase II activity
F3P16_RS00030	COG0586	Pfam SNARE associated Golgi protein
F3P16_RS00035	COG0488	(ABC) transporter
F3P16_RS00060	COG0596	Alpha beta hydrolase
F3P16_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
F3P16_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
F3P16_RS00115	COG0733	neurotransmitter:sodium symporter activity
F3P16_RS00155	COG2233	PERMEase
F3P16_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P16_RS00205	COG2814	Major facilitator Superfamily
F3P16_RS00210	COG0656	L-ascorbic acid biosynthetic process
F3P16_RS00215	COG0583	DNA-binding transcription factor activity
F3P16_RS00235	COG1064	alcohol dehydrogenase
F3P16_RS00240	COG2818	Glycosylase
F3P16_RS00255	COG1194	a g-specific adenine glycosylase
F3P16_RS00265	COG0400	carboxylic ester hydrolase activity
F3P16_RS00275	COG2983	Belongs to the UPF0260 family
F3P16_RS00280	COG2133	pyrroloquinoline quinone binding
F3P16_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
F3P16_RS00290	COG2116	formate transmembrane transporter activity
F3P16_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P16_RS00315	COG1335	isochorismatase
F3P16_RS00320	COG0385	Bile acid
F3P16_RS00325	COG0534	Mate efflux family protein
F3P16_RS00330	COG1683	Conserved Protein
F3P16_RS00350	COG0625	glutathione transferase activity
F3P16_RS00360	COG1113	amino acid transport
F3P16_RS00370	COG0523	cobalamin synthesis protein
F3P16_RS00380	COG2188	Transcriptional regulator
F3P16_RS00410	COG0010	Belongs to the arginase family
F3P16_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F3P16_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3P16_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
F3P16_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
F3P16_RS00550	COG0534	Mate efflux family protein
F3P16_RS00555	COG0436	Aminotransferase
F3P16_RS00560	COG2733	membrane
F3P16_RS00575	COG2918	glutathione biosynthetic process
F3P16_RS00590	COG1388	LysM domain
F3P16_RS00590	COG3409	Peptidoglycan-binding domain 1 protein
F3P16_RS00590	COG5632	N-Acetylmuramoyl-L-alanine amidase
F3P16_RS00610	COG3150	esterase
F3P16_RS00620	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
F3P16_RS00630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3P16_RS00640	COG2233	PERMEase
F3P16_RS00645	COG2351	hydroxyisourate hydrolase activity
F3P16_RS00680	COG3706	GGDEF domain
F3P16_RS00695	COG1393	Belongs to the ArsC family
F3P16_RS00700	COG0708	Exodeoxyribonuclease III
F3P16_RS00720	COG0189	ligase activity
F3P16_RS00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
F3P16_RS00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3P16_RS00765	COG4942	peptidase
F3P16_RS00775	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3P16_RS00785	COG2119	membrane
F3P16_RS00790	COG4774	siderophore transport
F3P16_RS00795	COG0426	domain, Protein
F3P16_RS00795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P16_RS00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
F3P16_RS00840	COG1902	pentaerythritol trinitrate reductase activity
F3P16_RS00845	COG1519	Transferase
F3P16_RS00850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F3P16_RS00855	COG0668	transmembrane transport
F3P16_RS00865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3P16_RS00870	COG1335	isochorismatase
F3P16_RS00875	COG1522	sequence-specific DNA binding
F3P16_RS00900	COG0784	Response regulator, receiver
F3P16_RS00900	COG2198	Histidine kinase
F3P16_RS00900	COG2205	protein histidine kinase activity
F3P16_RS00905	COG3162	membrane
F3P16_RS00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3P16_RS00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3P16_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3P16_RS00940	COG1309	transcriptional regulator
F3P16_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
F3P16_RS00960	COG0351	phosphomethylpyrimidine kinase
F3P16_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F3P16_RS00970	COG2814	Major facilitator Superfamily
F3P16_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F3P16_RS00995	COG1113	amino acid transport
F3P16_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3P16_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS01020	COG1335	isochorismatase
F3P16_RS01050	COG2814	Major facilitator Superfamily
F3P16_RS01055	COG0583	DNA-binding transcription factor activity
F3P16_RS01075	COG0667	Aldo Keto reductase
F3P16_RS01115	COG1733	regulation of RNA biosynthetic process
F3P16_RS01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3P16_RS01195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
F3P16_RS01235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
F3P16_RS01265	COG0427	acetyl-CoA hydrolase
F3P16_RS01285	COG0659	secondary active sulfate transmembrane transporter activity
F3P16_RS01290	COG4221	oxidoreductase activity
F3P16_RS01295	COG2873	o-acetylhomoserine
F3P16_RS01300	COG0488	(ABC) transporter
F3P16_RS01385	COG0833	amino acid
F3P16_RS01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
F3P16_RS01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F3P16_RS01450	COG2226	methyltransferase
F3P16_RS01500	COG0070	glutamate synthase
F3P16_RS01500	COG0069	glutamate synthase activity
F3P16_RS01500	COG0067	glutamate synthase
F3P16_RS01505	COG0493	'glutamate synthase
F3P16_RS01515	COG1704	LemA family
F3P16_RS01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
F3P16_RS01535	COG3307	-O-antigen
F3P16_RS01555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F3P16_RS01570	COG0194	GDP metabolic process
F3P16_RS01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
F3P16_RS01640	COG5380	lipid catabolic process
F3P16_RS01645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
F3P16_RS01670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3P16_RS01675	COG0277	FAD linked oxidase domain protein
F3P16_RS01685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
F3P16_RS01690	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3P16_RS01705	COG1289	transmembrane transporter activity
F3P16_RS01715	COG0628	permease
F3P16_RS01720	COG1192	Involved in chromosome partitioning
F3P16_RS01750	COG0833	amino acid
F3P16_RS01755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3P16_RS01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3P16_RS01770	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS01810	COG0583	DNA-binding transcription factor activity
F3P16_RS01860	COG0517	IMP dehydrogenase activity
F3P16_RS01865	COG1983	PspC domain protein
F3P16_RS01875	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS01890	COG0408	coproporphyrinogen oxidase activity
F3P16_RS01910	COG0513	Belongs to the DEAD box helicase family
F3P16_RS01920	COG1127	ABC transporter
F3P16_RS01925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
F3P16_RS01935	COG2854	intermembrane phospholipid transfer
F3P16_RS01945	COG0598	Magnesium transport protein CorA
F3P16_RS01955	COG0494	nUDIX hydrolase
F3P16_RS01960	COG1040	competence protein
F3P16_RS01965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
F3P16_RS01980	COG2937	Belongs to the GPAT DAPAT family
F3P16_RS01985	COG1946	Acyl-CoA thioesterase
F3P16_RS01990	COG1301	dicarboxylic acid transport
F3P16_RS02005	COG1959	2 iron, 2 sulfur cluster binding
F3P16_RS02010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3P16_RS02010	COG1017	nitric oxide dioxygenase activity
F3P16_RS02015	COG0433	COG0433 Predicted ATPase
F3P16_RS02020	COG0626	cystathionine gamma-synthase activity
F3P16_RS02175	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
F3P16_RS02210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
F3P16_RS02215	COG0339	signal peptide processing
F3P16_RS02220	COG0557	exoribonuclease II activity
F3P16_RS02265	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3P16_RS02270	COG2169	Transcriptional regulator
F3P16_RS02280	COG1295	ribonuclease BN
F3P16_RS02315	COG1702	phosphate starvation-inducible protein PhoH
F3P16_RS02325	COG0739	heme binding
F3P16_RS02325	COG0741	lytic transglycosylase activity
F3P16_RS02325	COG1196	nuclear chromosome segregation
F3P16_RS02355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
F3P16_RS02360	COG1183	phosphatidylcholine synthase activity
F3P16_RS02405	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS02410	COG1309	transcriptional regulator
F3P16_RS02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3P16_RS02430	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS02450	COG2969	positive regulation of protein catabolic process
F3P16_RS02460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F3P16_RS02470	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
F3P16_RS02475	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
F3P16_RS02480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
F3P16_RS02500	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3P16_RS02510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3P16_RS02515	COG1408	metallophosphoesterase
F3P16_RS02525	COG2199	diguanylate cyclase activity
F3P16_RS02585	COG1607	acyl-coa hydrolase
F3P16_RS02615	COG2350	Protein conserved in bacteria
F3P16_RS02625	COG0613	PHP domain protein
F3P16_RS02630	COG3781	membrane
F3P16_RS02640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3P16_RS02645	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
F3P16_RS02655	COG1862	Preprotein translocase
F3P16_RS02690	COG4695	Portal protein
F3P16_RS02710	COG2205	protein histidine kinase activity
F3P16_RS02715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
F3P16_RS02735	COG0726	polysaccharide deacetylase
F3P16_RS02740	COG0463	Glycosyl transferase, family 2
F3P16_RS02745	COG0438	transferase activity, transferring glycosyl groups
F3P16_RS02810	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS02815	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS02825	COG2205	protein histidine kinase activity
F3P16_RS02830	COG0745	RESPONSE REGULATOR receiver
F3P16_RS02835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
F3P16_RS02855	COG2096	Adenosyltransferase
F3P16_RS02905	COG0285	dihydrofolate synthase activity
F3P16_RS02925	COG0450	alkyl hydroperoxide reductase
F3P16_RS02940	COG0477	Major facilitator Superfamily
F3P16_RS02945	COG1272	protein, Hemolysin III
F3P16_RS02955	COG2153	protein acetylation
F3P16_RS02975	COG0183	Belongs to the thiolase family
F3P16_RS02980	COG2207	Transcriptional regulator
F3P16_RS03000	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3P16_RS03020	COG0183	Belongs to the thiolase family
F3P16_RS03030	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
F3P16_RS03030	COG2885	chlorophyll binding
F3P16_RS03040	COG1690	Belongs to the RtcB family
F3P16_RS03045	COG0833	amino acid
F3P16_RS03055	COG2233	PERMEase
F3P16_RS03060	COG1217	gtp-binding protein TYPA
F3P16_RS03085	COG2094	Belongs to the DNA glycosylase MPG family
F3P16_RS03090	COG4772	TonB-dependent receptor
F3P16_RS03095	COG1902	pentaerythritol trinitrate reductase activity
F3P16_RS03110	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3P16_RS03115	COG0354	folic acid binding
F3P16_RS03125	COG3189	MarR family transcriptional regulator
F3P16_RS03130	COG2824	Alkylphosphonate utilization operon protein PhnA
F3P16_RS03135	COG3422	double-strand break repair
F3P16_RS03175	COG0840	transmembrane signaling receptor activity
F3P16_RS03195	COG5510	response to toxic substance
F3P16_RS03205	COG2832	Protein of unknown function (DUF454)
F3P16_RS03210	COG1376	ErfK ybiS ycfS ynhG family protein
F3P16_RS03250	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
F3P16_RS03260	COG1289	transmembrane transporter activity
F3P16_RS03265	COG2814	Major facilitator Superfamily
F3P16_RS03285	COG1115	amino acid carrier protein
F3P16_RS03290	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3P16_RS03295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3P16_RS03300	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
F3P16_RS03305	COG3590	peptidase
F3P16_RS03330	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3P16_RS03340	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
F3P16_RS03345	COG1077	Cell shape determining protein MreB Mrl
F3P16_RS03350	COG1792	Involved in formation and maintenance of cell shape
F3P16_RS03355	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
F3P16_RS03360	COG0424	maF-like protein
F3P16_RS03365	COG1530	ribonuclease E activity
F3P16_RS03375	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3P16_RS03385	COG0560	Phosphoserine phosphatase
F3P16_RS03395	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3P16_RS03420	COG2207	Transcriptional regulator
F3P16_RS03440	COG1113	amino acid transport
F3P16_RS03445	COG2828	Protein conserved in bacteria
F3P16_RS03450	COG0142	geranyltranstransferase activity
F3P16_RS03455	COG2315	Protein conserved in bacteria
F3P16_RS03470	COG1752	Esterase of the alpha-beta hydrolase superfamily
F3P16_RS03490	COG2194	sulfuric ester hydrolase activity
F3P16_RS03495	COG0745	RESPONSE REGULATOR receiver
F3P16_RS03500	COG0642	Histidine kinase
F3P16_RS03510	COG0004	ammonium transporteR
F3P16_RS03520	COG0583	DNA-binding transcription factor activity
F3P16_RS03540	COG0525	valine-tRNA ligase activity
F3P16_RS03550	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS03560	COG0393	Putative heavy-metal-binding
F3P16_RS03565	COG0393	Putative heavy-metal-binding
F3P16_RS03570	COG1538	Outer membrane efflux protein
F3P16_RS03580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P16_RS03585	COG0671	phosphoesterase, PA-phosphatase related
F3P16_RS03615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
F3P16_RS03630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
F3P16_RS03630	COG1648	precorrin-2 dehydrogenase activity
F3P16_RS03635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3P16_RS03640	COG1733	regulation of RNA biosynthetic process
F3P16_RS03650	COG0531	amino acid
F3P16_RS03665	COG0321	lipoyl(octanoyl) transferase activity
F3P16_RS03670	COG2921	Belongs to the UPF0250 family
F3P16_RS03705	COG2009	succinate dehydrogenase
F3P16_RS03710	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
F3P16_RS03715	COG1053	succinate dehydrogenase
F3P16_RS03720	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F3P16_RS03745	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3P16_RS03765	COG2354	Protein conserved in bacteria
F3P16_RS03770	COG2321	neutral zinc metallopeptidase
F3P16_RS03840	COG2843	Capsule synthesis protein
F3P16_RS03855	COG0589	response to stress
F3P16_RS03865	COG0251	oxidation-reduction process
F3P16_RS03870	COG1309	transcriptional regulator
F3P16_RS03885	COG0505	Belongs to the CarA family
F3P16_RS03910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3P16_RS03915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
F3P16_RS03965	COG0477	Major facilitator Superfamily
F3P16_RS03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
F3P16_RS03985	COG1597	lipid kinase activity
F3P16_RS03990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F3P16_RS04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3P16_RS04020	COG0584	glycerophosphoryl diester phosphodiesterase
F3P16_RS04040	COG0741	lytic transglycosylase activity
F3P16_RS04065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3P16_RS04095	COG1113	amino acid transport
F3P16_RS04185	COG0210	DNA helicase
F3P16_RS04200	COG1309	transcriptional regulator
F3P16_RS04230	COG2207	Transcriptional regulator
F3P16_RS04240	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F3P16_RS04265	COG1522	sequence-specific DNA binding
F3P16_RS04275	COG1113	amino acid transport
F3P16_RS04280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3P16_RS04285	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3P16_RS04295	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS04305	COG0477	Major facilitator Superfamily
F3P16_RS04310	COG0235	Class ii aldolase
F3P16_RS04330	COG0583	DNA-binding transcription factor activity
F3P16_RS04385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3P16_RS04400	COG0582	viral genome integration into host DNA
F3P16_RS04410	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3P16_RS04420	COG3811	Belongs to the UPF0386 family
F3P16_RS04465	COG0778	Nitroreductase
F3P16_RS04480	COG1929	Belongs to the glycerate kinase type-1 family
F3P16_RS04485	COG0243	molybdopterin cofactor binding
F3P16_RS04490	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
F3P16_RS04495	COG3339	Conserved Protein
F3P16_RS04505	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
F3P16_RS04520	COG1113	amino acid transport
F3P16_RS04530	COG0019	diaminopimelate decarboxylase activity
F3P16_RS04545	COG2267	carboxylic ester hydrolase activity
F3P16_RS04550	COG1280	lysine exporter protein (LysE YggA)
F3P16_RS04555	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
F3P16_RS04585	COG0463	Glycosyl transferase, family 2
F3P16_RS04605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P16_RS04635	COG4591	ABC-type transport system involved in lipoprotein release permease component
F3P16_RS04640	COG1136	(ABC) transporter
F3P16_RS04645	COG0658	competence protein
F3P16_RS04645	COG2333	competence protein COMEC
F3P16_RS04655	COG0616	signal peptide processing
F3P16_RS04655	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
F3P16_RS04660	COG0596	Alpha beta hydrolase
F3P16_RS04665	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
F3P16_RS04675	COG0628	permease
F3P16_RS04710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3P16_RS04730	COG0823	Involved in the tonB-independent uptake of proteins
F3P16_RS04750	COG0824	Thioesterase
F3P16_RS04755	COG1473	amidohydrolase
F3P16_RS04775	COG0047	phosphoribosylformylglycinamidine synthase activity
F3P16_RS04775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3P16_RS04780	COG2814	Major facilitator Superfamily
F3P16_RS04790	COG1024	Enoyl-CoA hydratase
F3P16_RS04795	COG1051	belongs to the nudix hydrolase family
F3P16_RS04795	COG1056	cytidyltransferase-related domain
F3P16_RS04805	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
F3P16_RS04820	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
F3P16_RS04835	COG4625	pathogenesis
F3P16_RS04840	COG0583	DNA-binding transcription factor activity
F3P16_RS04845	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
F3P16_RS04850	COG4208	sulfate ABC transporter
F3P16_RS04855	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
F3P16_RS04865	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
F3P16_RS04870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3P16_RS04875	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
F3P16_RS04895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3P16_RS04905	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
F3P16_RS04915	COG0681	Belongs to the peptidase S26 family
F3P16_RS04930	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
F3P16_RS04940	COG1381	Involved in DNA repair and RecF pathway recombination
F3P16_RS04945	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
F3P16_RS04955	COG4221	oxidoreductase activity
F3P16_RS04985	COG0443	Heat shock 70 kDa protein
F3P16_RS04995	COG0436	Aminotransferase
F3P16_RS05015	COG0556	nucleotide-excision repair
F3P16_RS05070	COG2070	2-Nitropropane dioxygenase
F3P16_RS05100	COG1215	transferase activity, transferring glycosyl groups
F3P16_RS05115	COG0415	Belongs to the DNA photolyase family
F3P16_RS05125	COG1252	NADH dehydrogenase
F3P16_RS05130	COG1686	Belongs to the peptidase S11 family
F3P16_RS05145	COG1187	pseudouridine synthase activity
F3P16_RS05170	COG0477	Major facilitator Superfamily
F3P16_RS05175	COG0583	DNA-binding transcription factor activity
F3P16_RS05180	COG1823	symporter activity
F3P16_RS05190	COG0612	Peptidase, M16
F3P16_RS05215	COG0352	thiamine-phosphate diphosphorylase activity
F3P16_RS05250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3P16_RS05260	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3P16_RS05275	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
F3P16_RS05280	COG0076	glutamate decarboxylase activity
F3P16_RS05290	COG1522	sequence-specific DNA binding
F3P16_RS05295	COG3961	Belongs to the TPP enzyme family
F3P16_RS05300	COG1113	amino acid transport
F3P16_RS05305	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
F3P16_RS05310	COG0573	inorganic phosphate transmembrane transporter activity
F3P16_RS05320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
F3P16_RS05325	COG0616	signal peptide processing
F3P16_RS05360	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
F3P16_RS05365	COG1686	Belongs to the peptidase S11 family
F3P16_RS05390	COG0583	DNA-binding transcription factor activity
F3P16_RS05395	COG1067	ATP-dependent peptidase activity
F3P16_RS05440	COG1966	Carbon starvation protein
F3P16_RS05445	COG2879	small protein
F3P16_RS05485	COG1335	isochorismatase
F3P16_RS05490	COG0583	DNA-binding transcription factor activity
F3P16_RS05505	COG0596	Alpha beta hydrolase
F3P16_RS05515	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3P16_RS05545	COG1741	Belongs to the pirin family
F3P16_RS05555	COG2964	Protein conserved in bacteria
F3P16_RS05570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3P16_RS05575	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3P16_RS05580	COG4605	iron ion homeostasis
F3P16_RS05585	COG4604	ABC transporter, ATP-binding protein
F3P16_RS05590	COG4607	ABC-type enterochelin transport system periplasmic component
F3P16_RS05595	COG4774	siderophore transport
F3P16_RS05605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
F3P16_RS05610	COG1021	2,3-dihydroxybenzoate-AMP ligase
F3P16_RS05615	COG1535	isochorismatase
F3P16_RS05615	COG3433	isochorismatase activity
F3P16_RS05630	COG1132	(ABC) transporter
F3P16_RS05635	COG1132	(ABC) transporter
F3P16_RS05640	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
F3P16_RS05650	COG1169	isochorismate synthase
F3P16_RS05665	COG3739	integral membrane protein
F3P16_RS05685	COG0302	gtp cyclohydrolase
F3P16_RS05695	COG1529	Aldehyde oxidase and xanthine dehydrogenase
F3P16_RS05725	COG0308	aminopeptidase N
F3P16_RS05730	COG0512	Glutamine amidotransferase of anthranilate synthase
F3P16_RS05745	COG0174	glutamine synthetase
F3P16_RS05755	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
F3P16_RS05785	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
F3P16_RS05790	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F3P16_RS05795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
F3P16_RS05815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F3P16_RS05820	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F3P16_RS05825	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
F3P16_RS05840	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS05845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F3P16_RS05850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3P16_RS05860	COG2223	nitrite transmembrane transporter activity
F3P16_RS05870	COG0024	Methionine aminopeptidase
F3P16_RS05875	COG0052	Belongs to the universal ribosomal protein uS2 family
F3P16_RS05890	COG2207	Transcriptional regulator
F3P16_RS05915	COG2951	lytic endotransglycosylase activity
F3P16_RS05920	COG0772	Belongs to the SEDS family
F3P16_RS05935	COG0842	Transport permease protein
F3P16_RS05940	COG1131	(ABC) transporter
F3P16_RS05945	COG0582	viral genome integration into host DNA
F3P16_RS06005	COG3620	sequence-specific DNA binding
F3P16_RS06225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P16_RS06240	COG4215	(ABC) transporter
F3P16_RS06245	COG4160	amino acid transport
F3P16_RS06250	COG4598	ABC transporter
F3P16_RS06260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3P16_RS06265	COG0826	peptidase U32
F3P16_RS06270	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3P16_RS06285	COG1720	tRNA m6t6A37 methyltransferase activity
F3P16_RS06295	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3P16_RS06310	COG0642	Histidine kinase
F3P16_RS06320	COG0494	nUDIX hydrolase
F3P16_RS06330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3P16_RS06335	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
F3P16_RS06340	COG3139	Protein of unknown function (DUF1315)
F3P16_RS06345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F3P16_RS06355	COG1301	dicarboxylic acid transport
F3P16_RS06360	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS06365	COG2819	hydrolase of the alpha beta superfamily
F3P16_RS06375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
F3P16_RS06385	COG2195	Cleaves the N-terminal amino acid of tripeptides
F3P16_RS06390	COG1234	tRNA 3'-trailer cleavage
F3P16_RS06420	COG2363	Small membrane protein
F3P16_RS06440	COG0513	Belongs to the DEAD box helicase family
F3P16_RS06450	COG0778	Nitroreductase
F3P16_RS06480	COG1286	toxin biosynthetic process
F3P16_RS06505	COG4783	chaperone-mediated protein folding
F3P16_RS06510	COG1610	YqeY-like protein
F3P16_RS06565	COG2831	hemolysin activation secretion protein
F3P16_RS06690	COG3111	PFAM Bacterial OB fold (BOF) protein
F3P16_RS06715	COG3243	poly(R)-hydroxyalkanoic acid synthase
F3P16_RS06720	COG0786	glutamate:sodium symporter activity
F3P16_RS06730	COG2186	Transcriptional regulator
F3P16_RS06780	COG0477	Major facilitator Superfamily
F3P16_RS06805	COG2985	domain, Protein
F3P16_RS06820	COG2995	paraquat-inducible protein a
F3P16_RS06825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
F3P16_RS06825	COG3008	intermembrane lipid transfer
F3P16_RS06835	COG2351	hydroxyisourate hydrolase activity
F3P16_RS06875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3P16_RS06885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
F3P16_RS06890	COG0642	Histidine kinase
F3P16_RS06895	COG0745	RESPONSE REGULATOR receiver
F3P16_RS06915	COG1794	racemase activity, acting on amino acids and derivatives
F3P16_RS06945	COG1301	dicarboxylic acid transport
F3P16_RS06955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3P16_RS06960	COG2011	ABC-type metal ion transport system permease component
F3P16_RS06965	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F3P16_RS06970	COG1464	Belongs to the NlpA lipoprotein family
F3P16_RS06975	COG0151	Belongs to the GarS family
F3P16_RS06980	COG0138	bifunctional purine biosynthesis protein purh
F3P16_RS06985	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
F3P16_RS07015	COG2308	Evidence 4 Homologs of previously reported genes of
F3P16_RS07025	COG1305	Transglutaminase-like
F3P16_RS07035	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3P16_RS07040	COG0305	Participates in initiation and elongation during chromosome replication
F3P16_RS07065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
F3P16_RS07075	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
F3P16_RS07080	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
F3P16_RS07105	COG0726	polysaccharide deacetylase
F3P16_RS07105	COG1649	PFAM Uncharacterised BCR, COG1649
F3P16_RS07110	COG1215	transferase activity, transferring glycosyl groups
F3P16_RS07115	COG3658	cytochrome
F3P16_RS07125	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P16_RS07145	COG0583	DNA-binding transcription factor activity
F3P16_RS07165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P16_RS07170	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P16_RS07185	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS07190	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3P16_RS07195	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P16_RS07220	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
F3P16_RS07225	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
F3P16_RS07235	COG2205	protein histidine kinase activity
F3P16_RS07240	COG0745	RESPONSE REGULATOR receiver
F3P16_RS07245	COG0174	glutamine synthetase
F3P16_RS07265	COG0729	surface antigen
F3P16_RS07295	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3P16_RS07300	COG2814	Major facilitator Superfamily
F3P16_RS07315	COG0583	DNA-binding transcription factor activity
F3P16_RS07330	COG1187	pseudouridine synthase activity
F3P16_RS07350	COG0802	atpase or kinase
F3P16_RS07355	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
F3P16_RS07365	COG1923	regulation of RNA biosynthetic process
F3P16_RS07370	COG0697	spore germination
F3P16_RS07385	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3P16_RS07395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3P16_RS07400	COG0519	Catalyzes the synthesis of GMP from XMP
F3P16_RS07400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F3P16_RS07405	COG4302	ethanolamine ammonia-lyase activity
F3P16_RS07410	COG4303	Ethanolamine ammonia lyase large subunit
F3P16_RS07415	COG0531	amino acid
F3P16_RS07435	COG1454	alcohol dehydrogenase
F3P16_RS07440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3P16_RS07465	COG0308	aminopeptidase N
F3P16_RS07495	COG4221	oxidoreductase activity
F3P16_RS07505	COG1605	Chorismate mutase
F3P16_RS07530	COG1309	transcriptional regulator
F3P16_RS07540	COG0668	transmembrane transport
F3P16_RS07570	COG4773	Receptor
F3P16_RS07595	COG0488	(ABC) transporter
F3P16_RS07600	COG0589	response to stress
F3P16_RS07615	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F3P16_RS07625	COG3135	benzoate transporter
F3P16_RS07630	COG1522	sequence-specific DNA binding
F3P16_RS07640	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3P16_RS07645	COG0583	DNA-binding transcription factor activity
F3P16_RS07655	COG0183	Belongs to the thiolase family
F3P16_RS07665	COG2030	dehydratase
F3P16_RS07670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3P16_RS07685	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F3P16_RS07695	COG0824	Thioesterase
F3P16_RS07700	COG1454	alcohol dehydrogenase
F3P16_RS07710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3P16_RS07740	COG0069	glutamate synthase activity
F3P16_RS07760	COG2814	Major facilitator Superfamily
F3P16_RS07775	COG0511	ligase activity, forming carbon-carbon bonds
F3P16_RS07795	COG1116	anion transmembrane transporter activity
F3P16_RS07795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P16_RS07800	COG0745	RESPONSE REGULATOR receiver
F3P16_RS07810	COG2146	nitrite reductase [NAD(P)H] activity
F3P16_RS07810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3P16_RS07815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3P16_RS07820	COG0243	molybdopterin cofactor binding
F3P16_RS07830	COG0243	molybdopterin cofactor binding
F3P16_RS07835	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
F3P16_RS07850	COG0521	Mo-molybdopterin cofactor biosynthetic process
F3P16_RS07850	COG0315	cyclic pyranopterin monophosphate synthase activity
F3P16_RS07865	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3P16_RS07870	COG0697	spore germination
F3P16_RS07890	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
F3P16_RS07895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3P16_RS07955	COG2204	response regulator
F3P16_RS07960	COG3852	Histidine kinase
F3P16_RS07985	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
F3P16_RS07990	COG0575	Belongs to the CDS family
F3P16_RS08025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3P16_RS08040	COG2137	regulation of response to DNA damage stimulus
F3P16_RS08050	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
F3P16_RS08055	COG1011	Hydrolase
F3P16_RS08080	COG1522	sequence-specific DNA binding
F3P16_RS08090	COG1113	amino acid transport
F3P16_RS08105	COG0659	secondary active sulfate transmembrane transporter activity
F3P16_RS08110	COG2135	peptidase activity
F3P16_RS08125	COG5001	Diguanylate cyclase
F3P16_RS08125	COG3300	MHYT domain
F3P16_RS08145	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3P16_RS08145	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
F3P16_RS08145	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
F3P16_RS08150	COG1105	Belongs to the carbohydrate kinase PfkB family
F3P16_RS08155	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
F3P16_RS08155	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3P16_RS08185	COG0024	Methionine aminopeptidase
F3P16_RS08190	COG0583	DNA-binding transcription factor activity
F3P16_RS08200	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
F3P16_RS08205	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
F3P16_RS08210	COG0516	GMP reductase activity
F3P16_RS08210	COG0517	IMP dehydrogenase activity
F3P16_RS08235	COG0552	protein localization to endoplasmic reticulum
F3P16_RS08245	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
F3P16_RS08255	COG4890	Cyd operon protein YbgT
F3P16_RS08260	COG1294	oxidase, subunit
F3P16_RS08275	COG1585	Membrane protein implicated in regulation of membrane protease activity
F3P16_RS08285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3P16_RS08290	COG4774	siderophore transport
F3P16_RS08305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F3P16_RS08310	COG0569	domain protein
F3P16_RS08315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3P16_RS08345	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
F3P16_RS08350	COG0542	response to heat
F3P16_RS08375	COG1902	pentaerythritol trinitrate reductase activity
F3P16_RS08375	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3P16_RS08420	COG2323	membrane
F3P16_RS08425	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
F3P16_RS08435	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F3P16_RS08440	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3P16_RS08445	COG0183	Belongs to the thiolase family
F3P16_RS08450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3P16_RS08455	COG0596	Alpha beta hydrolase
F3P16_RS08460	COG2271	Major facilitator Superfamily
F3P16_RS08465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3P16_RS08470	COG3485	protocatechuate 3,4-dioxygenase
F3P16_RS08475	COG3485	protocatechuate 3,4-dioxygenase
F3P16_RS08480	COG0710	3-dehydroquinate dehydratase activity
F3P16_RS08485	COG3420	alginic acid biosynthetic process
F3P16_RS08490	COG3659	wide pore channel activity
F3P16_RS08495	COG4993	Dehydrogenase
F3P16_RS08505	COG2391	methyltransferase activity
F3P16_RS08520	COG1414	Transcriptional regulator
F3P16_RS08525	COG0583	DNA-binding transcription factor activity
F3P16_RS08530	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS08555	COG2814	Major facilitator Superfamily
F3P16_RS08565	COG0154	amidase activity
F3P16_RS08585	COG4638	Rieske (2fe-2S)
F3P16_RS08595	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS08605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P16_RS08615	COG3733	amine oxidase
F3P16_RS08625	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS08635	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F3P16_RS08640	COG0183	Belongs to the thiolase family
F3P16_RS08645	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3P16_RS08650	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F3P16_RS08660	COG4829	muconolactone delta-isomerase
F3P16_RS08665	COG4948	Mandelate Racemase Muconate Lactonizing
F3P16_RS08670	COG0583	DNA-binding transcription factor activity
F3P16_RS08680	COG2186	Transcriptional regulator
F3P16_RS08700	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS08715	COG1902	pentaerythritol trinitrate reductase activity
F3P16_RS08715	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3P16_RS08725	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
F3P16_RS08760	COG1309	transcriptional regulator
F3P16_RS08765	COG0583	DNA-binding transcription factor activity
F3P16_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS08775	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS08780	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS08790	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS08800	COG0318	PFAM AMP-dependent synthetase and ligase
F3P16_RS08895	COG2188	Transcriptional regulator
F3P16_RS08910	COG0583	DNA-binding transcription factor activity
F3P16_RS08940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3P16_RS08960	COG1566	PFAM secretion protein HlyD family protein
F3P16_RS08975	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS08980	COG0129	dihydroxy-acid dehydratase activity
F3P16_RS08990	COG0583	DNA-binding transcription factor activity
F3P16_RS08995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
F3P16_RS09005	COG2084	Dehydrogenase
F3P16_RS09010	COG2207	Transcriptional regulator
F3P16_RS09025	COG1064	alcohol dehydrogenase
F3P16_RS09035	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
F3P16_RS09040	COG1120	ATPase activity
F3P16_RS09060	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F3P16_RS09110	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
F3P16_RS09160	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
F3P16_RS09175	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS09190	COG2207	Transcriptional regulator
F3P16_RS09200	COG2205	protein histidine kinase activity
F3P16_RS09205	COG0745	RESPONSE REGULATOR receiver
F3P16_RS09210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P16_RS09215	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3P16_RS09230	COG3539	Fimbrial protein
F3P16_RS09255	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
F3P16_RS09265	COG0753	catalase activity
F3P16_RS09280	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
F3P16_RS09345	COG1535	isochorismatase
F3P16_RS09345	COG3433	isochorismatase activity
F3P16_RS09350	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS09355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
F3P16_RS09360	COG4149	molybdate abc transporter
F3P16_RS09365	COG0725	ABC transporter, periplasmic molybdate-binding protein
F3P16_RS09375	COG4638	Rieske (2fe-2S)
F3P16_RS09380	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F3P16_RS09385	COG0543	2 iron, 2 sulfur cluster binding
F3P16_RS09385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3P16_RS09400	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P16_RS09410	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS09425	COG2207	Transcriptional regulator
F3P16_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS09435	COG2610	gluconate transmembrane transporter activity
F3P16_RS09445	COG1309	transcriptional regulator
F3P16_RS09465	COG0583	DNA-binding transcription factor activity
F3P16_RS09480	COG2031	fatty acid transporter
F3P16_RS09485	COG0183	Belongs to the thiolase family
F3P16_RS09490	COG0583	DNA-binding transcription factor activity
F3P16_RS09495	COG0583	DNA-binding transcription factor activity
F3P16_RS09510	COG1027	Aspartate ammonia-lyase
F3P16_RS09520	COG0477	Major facilitator Superfamily
F3P16_RS09545	COG4521	taurine ABC transporter
F3P16_RS09560	COG2188	Transcriptional regulator
F3P16_RS09570	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
F3P16_RS09575	COG1733	regulation of RNA biosynthetic process
F3P16_RS09580	COG2207	Transcriptional regulator
F3P16_RS09580	COG3708	Transcriptional regulator
F3P16_RS09595	COG0730	response to heat
F3P16_RS09605	COG3453	Protein conserved in bacteria
F3P16_RS09605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3P16_RS09615	COG3781	membrane
F3P16_RS09620	COG1063	alcohol dehydrogenase
F3P16_RS09630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
F3P16_RS09635	COG0508	dehydrogenase complex catalyzes the overall conversion of
F3P16_RS09640	COG0022	dehydrogenase e1 component
F3P16_RS09645	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
F3P16_RS09650	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
F3P16_RS09665	COG3706	GGDEF domain
F3P16_RS09680	COG0133	tryptophan synthase activity
F3P16_RS09690	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3P16_RS09725	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
F3P16_RS09750	COG2226	methyltransferase
F3P16_RS09805	COG0842	Transport permease protein
F3P16_RS09810	COG0842	Transport permease protein
F3P16_RS09815	COG1131	(ABC) transporter
F3P16_RS09830	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
F3P16_RS09835	COG4773	Receptor
F3P16_RS09855	COG0730	response to heat
F3P16_RS09860	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3P16_RS09875	COG0406	alpha-ribazole phosphatase activity
F3P16_RS09880	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
F3P16_RS09895	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3P16_RS09925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3P16_RS09935	COG4264	IucA IucC family
F3P16_RS09940	COG4264	IucA IucC family
F3P16_RS09960	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3P16_RS09975	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS09980	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS09985	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
F3P16_RS09990	COG2207	Transcriptional regulator
F3P16_RS09995	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3P16_RS10000	COG0776	regulation of translation
F3P16_RS10025	COG0822	iron-sulfur transferase activity
F3P16_RS10030	COG0316	Belongs to the HesB IscA family
F3P16_RS10060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
F3P16_RS10080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
F3P16_RS10085	COG0702	epimerase
F3P16_RS10120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3P16_RS10130	COG0339	signal peptide processing
F3P16_RS10175	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
F3P16_RS10180	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
F3P16_RS10210	COG0776	regulation of translation
F3P16_RS10275	COG0084	hydrolase, TatD family'
F3P16_RS10295	COG1663	tetraacyldisaccharide 4'-kinase activity
F3P16_RS10300	COG1132	(ABC) transporter
F3P16_RS10310	COG0811	peptide transport
F3P16_RS10315	COG1475	DNA binding
F3P16_RS10320	COG1192	Involved in chromosome partitioning
F3P16_RS10330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3P16_RS10345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
F3P16_RS10350	COG0191	fructose-bisphosphate aldolase activity
F3P16_RS10370	COG0424	maF-like protein
F3P16_RS10375	COG2850	peptidyl-arginine hydroxylation
F3P16_RS10385	COG0640	Transcriptional regulator
F3P16_RS10395	COG3619	membrane
F3P16_RS10400	COG3122	Protein conserved in bacteria
F3P16_RS10405	COG1132	(ABC) transporter
F3P16_RS10425	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F3P16_RS10430	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3P16_RS10440	COG0506	proline dehydrogenase activity
F3P16_RS10440	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3P16_RS10440	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
F3P16_RS10445	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
F3P16_RS10460	COG3698	Phosphodiester glycosidase
F3P16_RS10470	COG2353	YceI-like domain
F3P16_RS10480	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
F3P16_RS10525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F3P16_RS10525	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F3P16_RS10550	COG3539	Fimbrial protein
F3P16_RS10555	COG3121	Chaperone
F3P16_RS10585	COG0697	spore germination
F3P16_RS10595	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F3P16_RS10605	COG0583	DNA-binding transcription factor activity
F3P16_RS10625	COG1309	transcriptional regulator
F3P16_RS10640	COG1522	sequence-specific DNA binding
F3P16_RS10650	COG1126	abc transporter atp-binding protein
F3P16_RS10655	COG0765	amino acid transport
F3P16_RS10660	COG0765	amino acid transport
F3P16_RS10690	COG1464	Belongs to the NlpA lipoprotein family
F3P16_RS10700	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F3P16_RS10705	COG2011	ABC-type metal ion transport system permease component
F3P16_RS10710	COG0012	GTP binding
F3P16_RS10735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F3P16_RS10775	COG0386	Belongs to the glutathione peroxidase family
F3P16_RS10785	COG0436	Aminotransferase
F3P16_RS10825	COG3634	alkyl hydroperoxide reductase activity
F3P16_RS10840	COG0583	DNA-binding transcription factor activity
F3P16_RS10845	COG0798	PFAM Bile acid sodium symporter
F3P16_RS10850	COG0640	Transcriptional regulator
F3P16_RS10865	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
F3P16_RS10875	COG0583	DNA-binding transcription factor activity
F3P16_RS10885	COG1953	Uracil, thiamine, allantoin
F3P16_RS10895	COG2175	clavaminate synthase activity
F3P16_RS10900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P16_RS10905	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
F3P16_RS10910	COG4521	taurine ABC transporter
F3P16_RS10920	COG0477	Major facilitator Superfamily
F3P16_RS10945	COG1271	oxidase subunit
F3P16_RS10950	COG1294	oxidase, subunit
F3P16_RS10960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3P16_RS10980	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
F3P16_RS11000	COG3052	prosthetic group binding
F3P16_RS11005	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
F3P16_RS11015	COG0583	DNA-binding transcription factor activity
F3P16_RS11025	COG2814	Major facilitator Superfamily
F3P16_RS11045	COG1346	cytolysis
F3P16_RS11055	COG0583	DNA-binding transcription factor activity
F3P16_RS11060	COG0625	glutathione transferase activity
F3P16_RS11065	COG0625	glutathione transferase activity
F3P16_RS11070	COG0583	DNA-binding transcription factor activity
F3P16_RS11085	COG1045	serine acetyltransferase
F3P16_RS11090	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
F3P16_RS11095	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
F3P16_RS11100	COG1280	lysine exporter protein (LysE YggA)
F3P16_RS11110	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P16_RS11115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P16_RS11125	COG0765	amino acid transport
F3P16_RS11130	COG0765	amino acid transport
F3P16_RS11150	COG0784	Response regulator, receiver
F3P16_RS11150	COG2205	protein histidine kinase activity
F3P16_RS11170	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
F3P16_RS11190	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS11240	COG0583	DNA-binding transcription factor activity
F3P16_RS11260	COG0318	PFAM AMP-dependent synthetase and ligase
F3P16_RS11265	COG1309	transcriptional regulator
F3P16_RS11270	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS11275	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3P16_RS11280	COG1024	Enoyl-CoA hydratase
F3P16_RS11285	COG4770	biotin carboxylase activity
F3P16_RS11295	COG0583	DNA-binding transcription factor activity
F3P16_RS11310	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS11320	COG2814	Major facilitator Superfamily
F3P16_RS11330	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
F3P16_RS11335	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
F3P16_RS11340	COG2814	Major facilitator Superfamily
F3P16_RS11345	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS11350	COG1024	Enoyl-CoA hydratase
F3P16_RS11355	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS11360	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3P16_RS11365	COG0183	Belongs to the thiolase family
F3P16_RS11375	COG2814	Major facilitator Superfamily
F3P16_RS11385	COG1024	Enoyl-CoA hydratase
F3P16_RS11400	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS11405	COG2814	Major facilitator Superfamily
F3P16_RS11410	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3P16_RS11415	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
F3P16_RS11430	COG3842	ATPase activity
F3P16_RS11435	COG1840	ABC-type Fe3 transport system, periplasmic component
F3P16_RS11445	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3P16_RS11450	COG1414	Transcriptional regulator
F3P16_RS11460	COG0583	DNA-binding transcription factor activity
F3P16_RS11465	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
F3P16_RS11470	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS11480	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
F3P16_RS11490	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS11495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P16_RS11500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P16_RS11505	COG2267	carboxylic ester hydrolase activity
F3P16_RS11525	COG3038	cytochrome b561
F3P16_RS11530	COG0753	catalase activity
F3P16_RS11535	COG2271	Major facilitator Superfamily
F3P16_RS11540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3P16_RS11545	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F3P16_RS11560	COG2207	Transcriptional regulator
F3P16_RS11595	COG2050	protein possibly involved in aromatic compounds catabolism
F3P16_RS11605	COG3327	negative regulation of DNA-templated transcription, initiation
F3P16_RS11610	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
F3P16_RS11615	COG0183	Belongs to the thiolase family
F3P16_RS11620	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3P16_RS11625	COG1024	Enoyl-CoA hydratase
F3P16_RS11630	COG1024	Enoyl-CoA hydratase
F3P16_RS11635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3P16_RS11640	COG2151	metal-sulfur cluster biosynthetic enzyme
F3P16_RS11645	COG3396	Phenylacetate-CoA oxygenase
F3P16_RS11650	COG3460	Phenylacetate-CoA oxygenase
F3P16_RS11655	COG3396	Phenylacetate-CoA oxygenase
F3P16_RS11660	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS11660	COG2030	dehydratase
F3P16_RS11665	COG1760	l-serine dehydratase
F3P16_RS11670	COG0531	amino acid
F3P16_RS11675	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS11700	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
F3P16_RS11720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P16_RS11735	COG0789	Transcriptional regulator
F3P16_RS11745	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
F3P16_RS11760	COG2807	transmembrane transport
F3P16_RS11765	COG0590	tRNA wobble adenosine to inosine editing
F3P16_RS11890	COG1116	anion transmembrane transporter activity
F3P16_RS11895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3P16_RS11905	COG0864	Transcriptional regulator
F3P16_RS11915	COG1733	regulation of RNA biosynthetic process
F3P16_RS11920	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3P16_RS11925	COG0439	Biotin carboxylase
F3P16_RS11940	COG1063	alcohol dehydrogenase
F3P16_RS11950	COG1309	transcriptional regulator
F3P16_RS11965	COG3210	domain, Protein
F3P16_RS11970	COG2831	hemolysin activation secretion protein
F3P16_RS11975	COG0038	chloride channel
F3P16_RS11980	COG4770	biotin carboxylase activity
F3P16_RS12000	COG1914	H( )-stimulated, divalent metal cation uptake system
F3P16_RS12005	COG0583	DNA-binding transcription factor activity
F3P16_RS12070	COG1250	3-hydroxyacyl-CoA dehydrogenase
F3P16_RS12110	COG4521	taurine ABC transporter
F3P16_RS12115	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P16_RS12120	COG1116	anion transmembrane transporter activity
F3P16_RS12125	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F3P16_RS12150	COG0598	Magnesium transport protein CorA
F3P16_RS12155	COG1560	Kdo2-lipid A biosynthetic process
F3P16_RS12165	COG5006	permease, DMT superfamily
F3P16_RS12170	COG1522	sequence-specific DNA binding
F3P16_RS12185	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
F3P16_RS12195	COG4122	O-methyltransferase activity
F3P16_RS12225	COG1538	Outer membrane efflux protein
F3P16_RS12230	COG1137	ATPase activity
F3P16_RS12235	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
F3P16_RS12245	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
F3P16_RS12250	COG0517	IMP dehydrogenase activity
F3P16_RS12250	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
F3P16_RS12295	COG2814	Major facilitator Superfamily
F3P16_RS12335	COG1278	Cold shock
F3P16_RS12340	COG1280	lysine exporter protein (LysE YggA)
F3P16_RS12370	COG1570	exodeoxyribonuclease VII activity
F3P16_RS12455	COG2871	sodium ion transport
F3P16_RS12465	COG0583	DNA-binding transcription factor activity
F3P16_RS12470	COG4638	Rieske (2fe-2S)
F3P16_RS12475	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
F3P16_RS12480	COG0633	Ferredoxin
F3P16_RS12480	COG0543	2 iron, 2 sulfur cluster binding
F3P16_RS12485	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS12490	COG3135	benzoate transporter
F3P16_RS12495	COG2814	Major facilitator Superfamily
F3P16_RS12510	COG1643	Atp-dependent helicase
F3P16_RS12515	COG0450	alkyl hydroperoxide reductase
F3P16_RS12525	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
F3P16_RS12535	COG3634	alkyl hydroperoxide reductase activity
F3P16_RS12555	COG0220	tRNA (guanine-N7-)-methyltransferase activity
F3P16_RS12580	COG0625	glutathione transferase activity
F3P16_RS12590	COG2885	chlorophyll binding
F3P16_RS12625	COG0542	response to heat
F3P16_RS12640	COG1765	OsmC-like protein
F3P16_RS12650	COG0667	Aldo Keto reductase
F3P16_RS12665	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
F3P16_RS12680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
F3P16_RS12690	COG0527	aspartate kinase activity
F3P16_RS12700	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F3P16_RS12710	COG3038	cytochrome b561
F3P16_RS12715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
F3P16_RS12720	COG2252	PERMEase
F3P16_RS12730	COG2072	flavoprotein involved in K transport
F3P16_RS12745	COG1741	Belongs to the pirin family
F3P16_RS12750	COG1309	transcriptional regulator
F3P16_RS12760	COG0300	oxidoreductase activity
F3P16_RS12765	COG2072	flavoprotein involved in K transport
F3P16_RS12770	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
F3P16_RS12775	COG2207	Transcriptional regulator
F3P16_RS12815	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F3P16_RS12830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
F3P16_RS12845	COG2814	Major facilitator Superfamily
F3P16_RS12850	COG1024	Enoyl-CoA hydratase
F3P16_RS12855	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS12865	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS12890	COG2186	Transcriptional regulator
F3P16_RS12895	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS12905	COG4948	Mandelate Racemase Muconate Lactonizing
F3P16_RS12910	COG2271	Major facilitator Superfamily
F3P16_RS12915	COG2721	sulfolactate sulfo-lyase activity
F3P16_RS12920	COG0697	spore germination
F3P16_RS12955	COG1113	amino acid transport
F3P16_RS12975	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS12995	COG0531	amino acid
F3P16_RS13005	COG1113	amino acid transport
F3P16_RS13045	COG3209	COG3209 Rhs family protein
F3P16_RS13070	COG4269	membrane
F3P16_RS13085	COG1902	pentaerythritol trinitrate reductase activity
F3P16_RS13085	COG0446	pyridine nucleotide-disulphide oxidoreductase
F3P16_RS13100	COG4251	negative regulation of phosphorylation
F3P16_RS13100	COG5001	Diguanylate cyclase
F3P16_RS13100	COG3706	GGDEF domain
F3P16_RS13100	COG2203	Gaf domain
F3P16_RS13110	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3P16_RS13130	COG4172	Belongs to the ABC transporter superfamily
F3P16_RS13135	COG4239	(ABC) transporter, permease
F3P16_RS13140	COG4174	ABC transporter (Permease)
F3P16_RS13150	COG0741	lytic transglycosylase activity
F3P16_RS13150	COG1388	LysM domain
F3P16_RS13150	COG0741	lytic transglycosylase activity
F3P16_RS13150	COG1388	LysM domain
F3P16_RS13155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3P16_RS13195	COG0583	DNA-binding transcription factor activity
F3P16_RS13200	COG1279	arginine transmembrane transporter activity
F3P16_RS13220	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3P16_RS13225	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
F3P16_RS13230	COG0006	proline dipeptidase activity
F3P16_RS13265	COG2194	sulfuric ester hydrolase activity
F3P16_RS13330	COG0739	heme binding
F3P16_RS13560	COG0464	growth
F3P16_RS13610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F3P16_RS13635	COG3384	dioxygenase
F3P16_RS13645	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3P16_RS13650	COG2878	Part of a membrane complex involved in electron transport
F3P16_RS13655	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
F3P16_RS13680	COG0768	penicillin binding
F3P16_RS13685	COG0742	ribosomal rna small subunit methyltransferase
F3P16_RS13700	COG0830	nickel cation binding
F3P16_RS13710	COG0804	urea catabolic process
F3P16_RS13750	COG1253	flavin adenine dinucleotide binding
F3P16_RS13760	COG2851	Citrate transporter
F3P16_RS13810	COG1773	rubredoxin
F3P16_RS13815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
F3P16_RS13825	COG0583	DNA-binding transcription factor activity
F3P16_RS13855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
F3P16_RS13860	COG4181	ATPase activity
F3P16_RS13905	COG1262	PFAM Formylglycine-generating sulfatase enzyme
F3P16_RS13925	COG0306	phosphate transporter
F3P16_RS13935	COG3958	Transketolase
F3P16_RS13940	COG3959	Transketolase, thiamine diphosphate binding domain
F3P16_RS13945	COG2271	Major facilitator Superfamily
F3P16_RS13950	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS13955	COG0583	DNA-binding transcription factor activity
F3P16_RS13975	COG2223	nitrite transmembrane transporter activity
F3P16_RS13980	COG2207	Transcriptional regulator
F3P16_RS13985	COG2066	Belongs to the glutaminase family
F3P16_RS13990	COG0242	peptide deformylase activity
F3P16_RS13995	COG0477	Major facilitator Superfamily
F3P16_RS14005	COG0028	Belongs to the TPP enzyme family
F3P16_RS14020	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS14025	COG2267	carboxylic ester hydrolase activity
F3P16_RS14035	COG2271	Major facilitator Superfamily
F3P16_RS14050	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS14070	COG1414	Transcriptional regulator
F3P16_RS14085	COG1024	Enoyl-CoA hydratase
F3P16_RS14095	COG1215	transferase activity, transferring glycosyl groups
F3P16_RS14100	COG1649	PFAM Uncharacterised BCR, COG1649
F3P16_RS14100	COG0726	polysaccharide deacetylase
F3P16_RS14110	COG4681	YaeQ
F3P16_RS14120	COG0523	cobalamin synthesis protein
F3P16_RS14130	COG1607	acyl-coa hydrolase
F3P16_RS14140	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3P16_RS14145	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
F3P16_RS14150	COG1309	transcriptional regulator
F3P16_RS14175	COG2040	homocysteine
F3P16_RS14180	COG0531	amino acid
F3P16_RS14235	COG1595	DNA-templated transcription, initiation
F3P16_RS14245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P16_RS14250	COG0477	Major facilitator Superfamily
F3P16_RS14285	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F3P16_RS14300	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F3P16_RS14310	COG0405	Gamma-glutamyltransferase
F3P16_RS14315	COG2814	Major facilitator Superfamily
F3P16_RS14325	COG2050	protein possibly involved in aromatic compounds catabolism
F3P16_RS14340	COG1090	epimerase
F3P16_RS14360	COG0420	3'-5' exonuclease activity
F3P16_RS14385	COG0735	belongs to the Fur family
F3P16_RS14390	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
F3P16_RS14415	COG0121	glutamine amidotransferase
F3P16_RS14430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3P16_RS14440	COG0210	DNA helicase
F3P16_RS14445	COG2885	chlorophyll binding
F3P16_RS14450	COG0204	Acyl-transferase
F3P16_RS14465	COG2894	cell division
F3P16_RS14480	COG1280	lysine exporter protein (LysE YggA)
F3P16_RS14485	COG1674	ftsk spoiiie
F3P16_RS14485	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
F3P16_RS14490	COG0492	ferredoxin-NADP+ reductase activity
F3P16_RS14495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
F3P16_RS14505	COG0456	acetyltransferase
F3P16_RS14550	COG1981	membrane
F3P16_RS14565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
F3P16_RS14565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3P16_RS14585	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS14595	COG0657	acetylesterase activity
F3P16_RS14605	COG0473	3-isopropylmalate dehydrogenase activity
F3P16_RS14610	COG0583	DNA-binding transcription factor activity
F3P16_RS14630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3P16_RS14655	COG0564	pseudouridine synthase activity
F3P16_RS14665	COG0358	DNA primase activity
F3P16_RS14680	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
F3P16_RS14710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
F3P16_RS14740	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3P16_RS14750	COG0352	thiamine-phosphate diphosphorylase activity
F3P16_RS14750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F3P16_RS14750	COG0351	phosphomethylpyrimidine kinase
F3P16_RS14755	COG1652	LysM domain
F3P16_RS14780	COG1399	metal-binding, possibly nucleic acid-binding protein
F3P16_RS14785	COG3101	peptidyl-lysine hydroxylation
F3P16_RS14790	COG0009	L-threonylcarbamoyladenylate synthase
F3P16_RS14795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
F3P16_RS14800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
F3P16_RS14815	COG4106	trans-aconitate 2-methyltransferase activity
F3P16_RS14830	COG2226	methyltransferase
F3P16_RS14830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F3P16_RS14830	COG0596	Alpha beta hydrolase
F3P16_RS14835	COG1877	trehalose-phosphatase activity
F3P16_RS14840	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
F3P16_RS14845	COG2223	nitrite transmembrane transporter activity
F3P16_RS14865	COG1196	nuclear chromosome segregation
F3P16_RS14875	COG0730	response to heat
F3P16_RS14890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
F3P16_RS14900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3P16_RS14960	COG0489	protein tyrosine kinase activity
F3P16_RS14970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3P16_RS14970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3P16_RS15000	COG2515	1-aminocyclopropane-1-carboxylate deaminase
F3P16_RS15005	COG2081	HI0933 family
F3P16_RS15015	COG0668	transmembrane transport
F3P16_RS15035	COG0583	DNA-binding transcription factor activity
F3P16_RS15060	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
F3P16_RS15065	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3P16_RS15095	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
F3P16_RS15135	COG0745	RESPONSE REGULATOR receiver
F3P16_RS15155	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
F3P16_RS15160	COG0697	spore germination
F3P16_RS15195	COG0477	Major facilitator Superfamily
F3P16_RS15205	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS15260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
F3P16_RS15275	COG0583	DNA-binding transcription factor activity
F3P16_RS15305	COG0583	DNA-binding transcription factor activity
F3P16_RS15325	COG0583	DNA-binding transcription factor activity
F3P16_RS15330	COG1053	succinate dehydrogenase
F3P16_RS15340	COG1804	L-carnitine dehydratase bile acid-inducible protein F
F3P16_RS15345	COG2814	Major facilitator Superfamily
F3P16_RS15350	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS15355	COG0583	DNA-binding transcription factor activity
F3P16_RS15360	COG1063	alcohol dehydrogenase
F3P16_RS15390	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
F3P16_RS15395	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
F3P16_RS15400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3P16_RS15420	COG2132	Multicopper oxidase
F3P16_RS15430	COG0561	phosphatase activity
F3P16_RS15435	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3P16_RS15445	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
F3P16_RS15460	COG1214	PFAM Peptidase M22, glycoprotease
F3P16_RS15510	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
F3P16_RS15520	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
F3P16_RS15525	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
F3P16_RS15530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F3P16_RS15590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3P16_RS15600	COG1846	Transcriptional regulator
F3P16_RS15605	COG1764	response to oxidative stress
F3P16_RS15645	COG0037	tRNA processing
F3P16_RS15655	COG0248	Ppx GppA phosphatase
F3P16_RS15685	COG0072	phenylalanine-tRNA ligase activity
F3P16_RS15725	COG1238	metal cluster binding
F3P16_RS15730	COG0625	glutathione transferase activity
F3P16_RS15745	COG0318	PFAM AMP-dependent synthetase and ligase
F3P16_RS15750	COG3028	Belongs to the UPF0307 family
F3P16_RS15775	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
F3P16_RS15780	COG0617	tRNA 3'-terminal CCA addition
F3P16_RS15785	COG1555	photosystem II stabilization
F3P16_RS15790	COG3956	TIGRFAM MazG family protein
F3P16_RS15800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F3P16_RS15820	COG2205	protein histidine kinase activity
F3P16_RS15820	COG5002	protein histidine kinase activity
F3P16_RS15820	COG0784	Response regulator, receiver
F3P16_RS15825	COG1024	Enoyl-CoA hydratase
F3P16_RS15830	COG2084	Dehydrogenase
F3P16_RS15835	COG3622	Belongs to the hyi family
F3P16_RS15865	COG0697	spore germination
F3P16_RS15875	COG2814	Major facilitator Superfamily
F3P16_RS15895	COG2132	Multicopper oxidase
F3P16_RS15910	COG2205	protein histidine kinase activity
F3P16_RS16000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
F3P16_RS16010	COG0583	DNA-binding transcription factor activity
F3P16_RS16020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
F3P16_RS16030	COG0084	hydrolase, TatD family'
F3P16_RS16045	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
F3P16_RS16080	COG0440	acetolactate synthase activity
F3P16_RS16085	COG0028	Belongs to the TPP enzyme family
F3P16_RS16110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
F3P16_RS16115	COG1136	(ABC) transporter
F3P16_RS16115	COG0577	efflux transmembrane transporter activity
F3P16_RS16120	COG1538	Outer membrane efflux protein
F3P16_RS16135	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
F3P16_RS16140	COG1162	GTPase activity
F3P16_RS16150	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
F3P16_RS16190	COG1426	Protein conserved in bacteria
F3P16_RS16225	COG0793	Belongs to the peptidase S41A family
F3P16_RS16240	COG2267	carboxylic ester hydrolase activity
F3P16_RS16250	COG1012	belongs to the aldehyde dehydrogenase family
F3P16_RS16255	COG3265	gluconokinase activity
F3P16_RS16265	COG0800	Aldolase
F3P16_RS16275	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F3P16_RS16280	COG0857	belongs to the CobB CobQ family
F3P16_RS16280	COG0280	phosphate acetyltransferase
F3P16_RS16285	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
F3P16_RS16285	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
F3P16_RS16305	COG0740	serine-type endopeptidase activity
F3P16_RS16315	COG4774	siderophore transport
F3P16_RS16325	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
F3P16_RS16335	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
F3P16_RS16335	COG2813	Specifically methylates the guanine in position
F3P16_RS16435	COG0788	formyltetrahydrofolate deformylase activity
F3P16_RS16460	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3P16_RS16460	COG4651	solute:proton antiporter activity
F3P16_RS16475	COG0724	RNA recognition motif
F3P16_RS16480	COG0210	DNA helicase
F3P16_RS16505	COG1733	regulation of RNA biosynthetic process
F3P16_RS16515	COG2900	Belongs to the SlyX family
F3P16_RS16520	COG0488	(ABC) transporter
F3P16_RS16525	COG1280	lysine exporter protein (LysE YggA)
F3P16_RS16530	COG1560	Kdo2-lipid A biosynthetic process
F3P16_RS16540	COG1301	dicarboxylic acid transport
F3P16_RS16595	COG0473	3-isopropylmalate dehydrogenase activity
F3P16_RS16660	COG0583	DNA-binding transcription factor activity
F3P16_RS16670	COG0625	glutathione transferase activity
F3P16_RS16675	COG2378	regulation of single-species biofilm formation
F3P16_RS16680	COG0546	phosphoglycolate phosphatase activity
F3P16_RS16695	COG1530	ribonuclease E activity
F3P16_RS16700	COG0318	PFAM AMP-dependent synthetase and ligase
F3P16_RS16715	COG0583	DNA-binding transcription factor activity
F3P16_RS16720	COG4221	oxidoreductase activity
F3P16_RS16725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
F3P16_RS16735	COG0534	Mate efflux family protein
F3P16_RS16750	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
F3P16_RS16775	COG0493	'glutamate synthase
F3P16_RS16775	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
F3P16_RS16785	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
F3P16_RS16790	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
F3P16_RS16805	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
F3P16_RS16815	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
F3P16_RS16815	COG0644	oxidoreductase
F3P16_RS16825	COG0425	Belongs to the sulfur carrier protein TusA family
F3P16_RS16830	COG4535	Mg2 and Co2 transporter CorC
F3P16_RS16840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
F3P16_RS16860	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F3P16_RS16865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3P16_RS16865	COG0475	glutathione-regulated potassium exporter activity
F3P16_RS16880	COG0484	heat shock protein binding
F3P16_RS16885	COG0789	Transcriptional regulator
F3P16_RS16890	COG0598	Magnesium transport protein CorA
F3P16_RS16905	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
F3P16_RS16910	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3P16_RS16915	COG1074	ATP-dependent DNA helicase activity
F3P16_RS16920	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
F3P16_RS16940	COG2226	methyltransferase
F3P16_RS16960	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
F3P16_RS16975	COG2111	Na H antiporter
F3P16_RS16975	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
F3P16_RS16980	COG1006	Multisubunit Na H antiporter MnhC subunit
F3P16_RS16985	COG0651	ATP synthesis coupled electron transport
F3P16_RS16990	COG1863	multisubunit Na H antiporter MnhE subunit
F3P16_RS16995	COG2212	antiporter activity
F3P16_RS17000	COG1320	monovalent cation:proton antiporter activity
F3P16_RS17015	COG0195	Participates in both transcription termination and antitermination
F3P16_RS17065	COG0237	dephospho-CoA kinase activity
F3P16_RS17075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3P16_RS17090	COG0497	DNA recombination
F3P16_RS17100	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
F3P16_RS17130	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
F3P16_RS17130	COG2169	Transcriptional regulator
F3P16_RS17135	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3P16_RS17200	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
F3P16_RS17215	COG0326	Molecular chaperone. Has ATPase activity
F3P16_RS17230	COG2056	Na+-H+ antiporter family
F3P16_RS17235	COG0596	Alpha beta hydrolase
F3P16_RS17330	COG0546	phosphoglycolate phosphatase activity
F3P16_RS17335	COG1716	ATPase activity
F3P16_RS17380	COG0181	hydroxymethylbilane synthase activity
F3P16_RS17390	COG3275	phosphorelay sensor kinase activity
F3P16_RS17410	COG1538	Outer membrane efflux protein
F3P16_RS17415	COG0697	spore germination
F3P16_RS17440	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
F3P16_RS17445	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
F3P16_RS17450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
F3P16_RS17455	COG0772	Belongs to the SEDS family
F3P16_RS17480	COG4974	Belongs to the 'phage' integrase family
F3P16_RS17485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3P16_RS17495	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
F3P16_RS17505	COG2197	response regulator
F3P16_RS17520	COG0793	Belongs to the peptidase S41A family
F3P16_RS17525	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
F3P16_RS17530	COG0795	lipopolysaccharide-transporting ATPase activity
F3P16_RS17570	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3P16_RS17570	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
F3P16_RS17580	COG0004	ammonium transporteR
F3P16_RS17585	COG0347	Belongs to the P(II) protein family
F3P16_RS17595	COG0606	chelatase, subunit chli
F3P16_RS17600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3P16_RS17610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
F3P16_RS17625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F3P16_RS17640	COG0318	PFAM AMP-dependent synthetase and ligase
F3P16_RS17650	COG0477	Major facilitator Superfamily
F3P16_RS17655	COG2860	membrane
F3P16_RS17665	COG1253	flavin adenine dinucleotide binding
F3P16_RS17675	COG0477	Major facilitator Superfamily
F3P16_RS17685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3P16_RS17720	COG0655	NAD(P)H dehydrogenase (quinone) activity
F3P16_RS17730	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
F3P16_RS17765	COG1309	transcriptional regulator
F3P16_RS17800	COG0758	DNA mediated transformation
F3P16_RS17810	COG0697	spore germination
F3P16_RS17815	COG1309	transcriptional regulator
F3P16_RS17830	COG0386	Belongs to the glutathione peroxidase family
F3P16_RS17895	COG1121	(ABC) transporter
F3P16_RS17900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
F3P16_RS17905	COG1280	lysine exporter protein (LysE YggA)
F3P16_RS17910	COG2837	iron assimilation
F3P16_RS17915	COG0281	malic enzyme
F3P16_RS17960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
F3P16_RS17960	COG0519	Catalyzes the synthesis of GMP from XMP
F3P16_RS17965	COG4399	Belongs to the UPF0754 family
F3P16_RS17970	COG2259	Doxx family
F3P16_RS17975	COG0586	Pfam SNARE associated Golgi protein
F3P16_RS17990	COG1192	Involved in chromosome partitioning
F3P16_RS18000	COG0271	Belongs to the BolA IbaG family
F3P16_RS18020	COG2267	carboxylic ester hydrolase activity
F3P16_RS18040	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
F3P16_RS18040	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
F3P16_RS18040	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
F3P16_RS18040	COG3321	synthase
F3P16_RS18045	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS18055	COG2197	response regulator
F3P16_RS18065	COG3916	Acyl-homoserine-lactone synthase
F3P16_RS18070	COG0477	Major facilitator Superfamily
F3P16_RS18075	COG1024	Enoyl-CoA hydratase
F3P16_RS18080	COG1024	Enoyl-CoA hydratase
F3P16_RS18085	COG1960	acyl-CoA dehydrogenase activity
F3P16_RS18090	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
F3P16_RS18110	COG1113	amino acid transport
F3P16_RS18115	COG1113	amino acid transport
F3P16_RS18120	COG0251	oxidation-reduction process
F3P16_RS18160	COG0564	pseudouridine synthase activity
F3P16_RS18225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3P16_RS18240	COG1802	Transcriptional regulator
F3P16_RS18250	COG1448	Aminotransferase
F3P16_RS18255	COG0277	FAD linked oxidase domain protein
F3P16_RS18265	COG2186	Transcriptional regulator
F3P16_RS18275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
F3P16_RS18280	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3P16_RS18295	COG1210	Utp--glucose-1-phosphate uridylyltransferase
F3P16_RS18300	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3P16_RS18325	COG2244	polysaccharide biosynthetic process
F3P16_RS18330	COG1083	cytidylyl-transferase
F3P16_RS18335	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
F3P16_RS18345	COG2089	acid synthase
F3P16_RS18350	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
F3P16_RS18355	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
F3P16_RS18365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
F3P16_RS18370	COG1596	polysaccharide export
F3P16_RS18395	COG0728	peptidoglycan biosynthetic process
F3P16_RS18400	COG3023	N-Acetylmuramoyl-L-alanine amidase
F3P16_RS18455	COG0546	phosphoglycolate phosphatase activity
F3P16_RS18460	COG1028	Short-chain dehydrogenase reductase Sdr
F3P16_RS18480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P16_RS18485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
F3P16_RS18490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
F3P16_RS18495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3P16_RS18500	COG1116	anion transmembrane transporter activity
F3P16_RS18505	COG1309	transcriptional regulator
F3P16_RS18510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3P16_RS18525	COG0196	riboflavin kinase activity
F3P16_RS18530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
F3P16_RS18540	COG1047	Peptidyl-prolyl cis-trans
F3P16_RS18580	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
F3P16_RS18585	COG0657	acetylesterase activity
F3P16_RS18635	COG2951	lytic endotransglycosylase activity
F3P16_RS18640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3P16_RS18660	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
F3P16_RS18670	COG0671	phosphoesterase, PA-phosphatase related
F3P16_RS18675	COG0861	Integral membrane protein TerC family
F3P16_RS18685	COG0754	glutathionylspermidine amidase activity
F3P16_RS18695	COG0402	S-adenosylhomocysteine deaminase activity
F3P16_RS18710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
F3P16_RS18715	COG1230	cation diffusion facilitator family transporter
F3P16_RS18730	COG0706	membrane insertase activity
F3P16_RS18780	COG1192	Involved in chromosome partitioning
F3P16_RS18795	COG4683	PFAM Phage derived protein Gp49-like (DUF891)