locus-tag	class	description
J6E47_RS00010	COG0592	DNA-directed DNA polymerase activity
J6E47_RS00020	COG0187	DNA topoisomerase II activity
J6E47_RS00030	COG0586	Pfam SNARE associated Golgi protein
J6E47_RS00035	COG0488	(ABC) transporter
J6E47_RS00060	COG0596	Alpha beta hydrolase
J6E47_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
J6E47_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
J6E47_RS00110	COG0733	neurotransmitter:sodium symporter activity
J6E47_RS00120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
J6E47_RS00145	COG0583	DNA-binding transcription factor activity
J6E47_RS00150	COG2233	PERMEase
J6E47_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6E47_RS00200	COG2814	Major facilitator Superfamily
J6E47_RS00205	COG0656	L-ascorbic acid biosynthetic process
J6E47_RS00210	COG0583	DNA-binding transcription factor activity
J6E47_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6E47_RS00230	COG1064	alcohol dehydrogenase
J6E47_RS00235	COG2818	Glycosylase
J6E47_RS00250	COG1194	a g-specific adenine glycosylase
J6E47_RS00260	COG0400	carboxylic ester hydrolase activity
J6E47_RS00270	COG2983	Belongs to the UPF0260 family
J6E47_RS00275	COG2133	pyrroloquinoline quinone binding
J6E47_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
J6E47_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6E47_RS00310	COG1335	isochorismatase
J6E47_RS00315	COG0385	Bile acid
J6E47_RS00320	COG0534	Mate efflux family protein
J6E47_RS00325	COG1683	Conserved Protein
J6E47_RS00345	COG0625	glutathione transferase activity
J6E47_RS00355	COG1113	amino acid transport
J6E47_RS00365	COG0523	cobalamin synthesis protein
J6E47_RS00375	COG2188	Transcriptional regulator
J6E47_RS00405	COG0010	Belongs to the arginase family
J6E47_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J6E47_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J6E47_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
J6E47_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
J6E47_RS00485	COG0753	catalase activity
J6E47_RS00545	COG0534	Mate efflux family protein
J6E47_RS00550	COG0436	Aminotransferase
J6E47_RS00555	COG2733	membrane
J6E47_RS00570	COG2918	glutathione biosynthetic process
J6E47_RS00595	COG2826	transposase and inactivated derivatives, IS30 family
J6E47_RS00620	COG1324	tolerance protein
J6E47_RS00625	COG0673	inositol 2-dehydrogenase activity
J6E47_RS00645	COG2826	transposase and inactivated derivatives, IS30 family
J6E47_RS00665	COG3150	esterase
J6E47_RS00675	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS00680	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
J6E47_RS00690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6E47_RS00700	COG2233	PERMEase
J6E47_RS00705	COG2351	hydroxyisourate hydrolase activity
J6E47_RS00740	COG3706	GGDEF domain
J6E47_RS00755	COG1393	Belongs to the ArsC family
J6E47_RS00760	COG0708	Exodeoxyribonuclease III
J6E47_RS00780	COG0189	ligase activity
J6E47_RS00800	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
J6E47_RS00810	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J6E47_RS00825	COG4942	peptidase
J6E47_RS00835	COG0508	dehydrogenase complex catalyzes the overall conversion of
J6E47_RS00845	COG2119	membrane
J6E47_RS00850	COG4774	siderophore transport
J6E47_RS00855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6E47_RS00855	COG0426	domain, Protein
J6E47_RS00880	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
J6E47_RS00900	COG1902	pentaerythritol trinitrate reductase activity
J6E47_RS00905	COG1519	Transferase
J6E47_RS00910	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J6E47_RS00915	COG0668	transmembrane transport
J6E47_RS00925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6E47_RS00930	COG1335	isochorismatase
J6E47_RS00935	COG1522	sequence-specific DNA binding
J6E47_RS00960	COG2205	protein histidine kinase activity
J6E47_RS00960	COG2198	Histidine kinase
J6E47_RS00960	COG0784	Response regulator, receiver
J6E47_RS00965	COG3162	membrane
J6E47_RS00970	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6E47_RS00980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6E47_RS01000	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
J6E47_RS01005	COG1309	transcriptional regulator
J6E47_RS01025	COG0352	thiamine-phosphate diphosphorylase activity
J6E47_RS01025	COG0351	phosphomethylpyrimidine kinase
J6E47_RS01025	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J6E47_RS01035	COG2814	Major facilitator Superfamily
J6E47_RS01050	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J6E47_RS01060	COG1113	amino acid transport
J6E47_RS01070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J6E47_RS01075	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS01085	COG1335	isochorismatase
J6E47_RS01115	COG2814	Major facilitator Superfamily
J6E47_RS01120	COG0583	DNA-binding transcription factor activity
J6E47_RS01140	COG0667	Aldo Keto reductase
J6E47_RS01175	COG1733	regulation of RNA biosynthetic process
J6E47_RS01180	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6E47_RS01250	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J6E47_RS01265	COG2329	Antibiotic biosynthesis monooxygenase
J6E47_RS01295	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
J6E47_RS01325	COG0427	acetyl-CoA hydrolase
J6E47_RS01350	COG0659	secondary active sulfate transmembrane transporter activity
J6E47_RS01355	COG4221	oxidoreductase activity
J6E47_RS01360	COG2873	o-acetylhomoserine
J6E47_RS01365	COG0488	(ABC) transporter
J6E47_RS01450	COG0833	amino acid
J6E47_RS01495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
J6E47_RS01500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J6E47_RS01515	COG2226	methyltransferase
J6E47_RS01565	COG0070	glutamate synthase
J6E47_RS01565	COG0067	glutamate synthase
J6E47_RS01565	COG0069	glutamate synthase activity
J6E47_RS01570	COG0493	'glutamate synthase
J6E47_RS01580	COG1704	LemA family
J6E47_RS01585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
J6E47_RS01600	COG3307	-O-antigen
J6E47_RS01620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J6E47_RS01635	COG0194	GDP metabolic process
J6E47_RS01685	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
J6E47_RS01705	COG5380	lipid catabolic process
J6E47_RS01710	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
J6E47_RS01735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J6E47_RS01740	COG0277	FAD linked oxidase domain protein
J6E47_RS01750	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
J6E47_RS01755	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6E47_RS01770	COG1289	transmembrane transporter activity
J6E47_RS01780	COG0628	permease
J6E47_RS01785	COG1192	Involved in chromosome partitioning
J6E47_RS01815	COG0833	amino acid
J6E47_RS01820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J6E47_RS01825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J6E47_RS01835	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS01875	COG0583	DNA-binding transcription factor activity
J6E47_RS01925	COG0517	IMP dehydrogenase activity
J6E47_RS01930	COG1983	PspC domain protein
J6E47_RS01940	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS01960	COG0408	coproporphyrinogen oxidase activity
J6E47_RS01980	COG0513	Belongs to the DEAD box helicase family
J6E47_RS01990	COG1127	ABC transporter
J6E47_RS01995	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
J6E47_RS02005	COG2854	intermembrane phospholipid transfer
J6E47_RS02015	COG0598	Magnesium transport protein CorA
J6E47_RS02025	COG0494	nUDIX hydrolase
J6E47_RS02030	COG1040	competence protein
J6E47_RS02035	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
J6E47_RS02055	COG1946	Acyl-CoA thioesterase
J6E47_RS02060	COG1301	dicarboxylic acid transport
J6E47_RS02075	COG1959	2 iron, 2 sulfur cluster binding
J6E47_RS02080	COG1017	nitric oxide dioxygenase activity
J6E47_RS02080	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6E47_RS02090	COG0433	COG0433 Predicted ATPase
J6E47_RS02095	COG0626	cystathionine gamma-synthase activity
J6E47_RS02250	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS02255	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
J6E47_RS02285	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
J6E47_RS02290	COG0339	signal peptide processing
J6E47_RS02295	COG0557	exoribonuclease II activity
J6E47_RS02345	COG0179	Fumarylacetoacetate (FAA) hydrolase
J6E47_RS02350	COG2169	Transcriptional regulator
J6E47_RS02355	COG0697	spore germination
J6E47_RS02360	COG1295	ribonuclease BN
J6E47_RS02395	COG1702	phosphate starvation-inducible protein PhoH
J6E47_RS02405	COG1196	nuclear chromosome segregation
J6E47_RS02405	COG0741	lytic transglycosylase activity
J6E47_RS02405	COG0739	heme binding
J6E47_RS02435	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
J6E47_RS02440	COG1183	phosphatidylcholine synthase activity
J6E47_RS02485	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS02490	COG1309	transcriptional regulator
J6E47_RS02505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J6E47_RS02510	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS02550	COG2969	positive regulation of protein catabolic process
J6E47_RS02560	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
J6E47_RS02575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
J6E47_RS02580	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
J6E47_RS02600	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J6E47_RS02610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6E47_RS02615	COG1408	metallophosphoesterase
J6E47_RS02625	COG2199	diguanylate cyclase activity
J6E47_RS02685	COG1607	acyl-coa hydrolase
J6E47_RS02715	COG2350	Protein conserved in bacteria
J6E47_RS02725	COG0613	PHP domain protein
J6E47_RS02730	COG3781	membrane
J6E47_RS02740	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J6E47_RS02745	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
J6E47_RS02755	COG1862	Preprotein translocase
J6E47_RS02855	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6E47_RS02985	COG4695	Portal protein
J6E47_RS03005	COG2205	protein histidine kinase activity
J6E47_RS03010	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
J6E47_RS03030	COG0726	polysaccharide deacetylase
J6E47_RS03035	COG0463	Glycosyl transferase, family 2
J6E47_RS03040	COG0438	transferase activity, transferring glycosyl groups
J6E47_RS03105	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS03110	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS03120	COG2205	protein histidine kinase activity
J6E47_RS03125	COG0745	RESPONSE REGULATOR receiver
J6E47_RS03130	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
J6E47_RS03150	COG2096	Adenosyltransferase
J6E47_RS03200	COG0285	dihydrofolate synthase activity
J6E47_RS03220	COG0450	alkyl hydroperoxide reductase
J6E47_RS03235	COG0477	Major facilitator Superfamily
J6E47_RS03240	COG1272	protein, Hemolysin III
J6E47_RS03260	COG2153	protein acetylation
J6E47_RS03280	COG0183	Belongs to the thiolase family
J6E47_RS03285	COG2207	Transcriptional regulator
J6E47_RS03305	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6E47_RS03325	COG0183	Belongs to the thiolase family
J6E47_RS03335	COG2885	chlorophyll binding
J6E47_RS03335	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
J6E47_RS03345	COG1690	Belongs to the RtcB family
J6E47_RS03350	COG0833	amino acid
J6E47_RS03360	COG2233	PERMEase
J6E47_RS03365	COG1217	gtp-binding protein TYPA
J6E47_RS03390	COG2094	Belongs to the DNA glycosylase MPG family
J6E47_RS03395	COG4772	TonB-dependent receptor
J6E47_RS03400	COG1902	pentaerythritol trinitrate reductase activity
J6E47_RS03415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6E47_RS03420	COG0354	folic acid binding
J6E47_RS03430	COG3189	MarR family transcriptional regulator
J6E47_RS03435	COG2824	Alkylphosphonate utilization operon protein PhnA
J6E47_RS03440	COG3422	double-strand break repair
J6E47_RS03480	COG0840	transmembrane signaling receptor activity
J6E47_RS03500	COG5510	response to toxic substance
J6E47_RS03510	COG2832	Protein of unknown function (DUF454)
J6E47_RS03515	COG1376	ErfK ybiS ycfS ynhG family protein
J6E47_RS03555	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
J6E47_RS03565	COG1289	transmembrane transporter activity
J6E47_RS03570	COG2814	Major facilitator Superfamily
J6E47_RS03590	COG1115	amino acid carrier protein
J6E47_RS03595	COG1752	Esterase of the alpha-beta hydrolase superfamily
J6E47_RS03600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J6E47_RS03605	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
J6E47_RS03610	COG3590	peptidase
J6E47_RS03635	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J6E47_RS03645	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
J6E47_RS03650	COG1077	Cell shape determining protein MreB Mrl
J6E47_RS03655	COG1792	Involved in formation and maintenance of cell shape
J6E47_RS03660	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
J6E47_RS03665	COG0424	maF-like protein
J6E47_RS03670	COG1530	ribonuclease E activity
J6E47_RS03680	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J6E47_RS03690	COG0560	Phosphoserine phosphatase
J6E47_RS03700	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6E47_RS03725	COG2207	Transcriptional regulator
J6E47_RS03745	COG1113	amino acid transport
J6E47_RS03750	COG2828	Protein conserved in bacteria
J6E47_RS03755	COG0142	geranyltranstransferase activity
J6E47_RS03760	COG2315	Protein conserved in bacteria
J6E47_RS03775	COG1752	Esterase of the alpha-beta hydrolase superfamily
J6E47_RS03795	COG2194	sulfuric ester hydrolase activity
J6E47_RS03800	COG0745	RESPONSE REGULATOR receiver
J6E47_RS03805	COG0642	Histidine kinase
J6E47_RS03815	COG0004	ammonium transporteR
J6E47_RS03820	COG0583	DNA-binding transcription factor activity
J6E47_RS03840	COG0525	valine-tRNA ligase activity
J6E47_RS03850	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS03860	COG0393	Putative heavy-metal-binding
J6E47_RS03865	COG0393	Putative heavy-metal-binding
J6E47_RS03870	COG1538	Outer membrane efflux protein
J6E47_RS03880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6E47_RS03885	COG0671	phosphoesterase, PA-phosphatase related
J6E47_RS03915	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
J6E47_RS03930	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
J6E47_RS03930	COG1648	precorrin-2 dehydrogenase activity
J6E47_RS03935	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J6E47_RS03940	COG1733	regulation of RNA biosynthetic process
J6E47_RS03950	COG0531	amino acid
J6E47_RS03965	COG0321	lipoyl(octanoyl) transferase activity
J6E47_RS03970	COG2921	Belongs to the UPF0250 family
J6E47_RS04005	COG2009	succinate dehydrogenase
J6E47_RS04010	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
J6E47_RS04015	COG1053	succinate dehydrogenase
J6E47_RS04020	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J6E47_RS04045	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6E47_RS04065	COG2354	Protein conserved in bacteria
J6E47_RS04070	COG2321	neutral zinc metallopeptidase
J6E47_RS04090	COG2843	Capsule synthesis protein
J6E47_RS04105	COG0589	response to stress
J6E47_RS04115	COG0251	oxidation-reduction process
J6E47_RS04120	COG1309	transcriptional regulator
J6E47_RS04135	COG0505	Belongs to the CarA family
J6E47_RS04160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J6E47_RS04165	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J6E47_RS04215	COG0477	Major facilitator Superfamily
J6E47_RS04220	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
J6E47_RS04235	COG1597	lipid kinase activity
J6E47_RS04240	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J6E47_RS04270	COG0584	glycerophosphoryl diester phosphodiesterase
J6E47_RS04290	COG0741	lytic transglycosylase activity
J6E47_RS04310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J6E47_RS04325	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J6E47_RS04335	COG3811	Belongs to the UPF0386 family
J6E47_RS04355	COG0778	Nitroreductase
J6E47_RS04370	COG1929	Belongs to the glycerate kinase type-1 family
J6E47_RS04375	COG0243	molybdopterin cofactor binding
J6E47_RS04380	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
J6E47_RS04385	COG3339	Conserved Protein
J6E47_RS04395	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
J6E47_RS04410	COG1113	amino acid transport
J6E47_RS04420	COG0019	diaminopimelate decarboxylase activity
J6E47_RS04430	COG1280	lysine exporter protein (LysE YggA)
J6E47_RS04435	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J6E47_RS04465	COG0463	Glycosyl transferase, family 2
J6E47_RS04485	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6E47_RS04520	COG4591	ABC-type transport system involved in lipoprotein release permease component
J6E47_RS04525	COG1136	(ABC) transporter
J6E47_RS04530	COG0658	competence protein
J6E47_RS04530	COG2333	competence protein COMEC
J6E47_RS04540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
J6E47_RS04540	COG0616	signal peptide processing
J6E47_RS04545	COG0596	Alpha beta hydrolase
J6E47_RS04550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
J6E47_RS04560	COG0628	permease
J6E47_RS04595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J6E47_RS04615	COG0823	Involved in the tonB-independent uptake of proteins
J6E47_RS04635	COG0824	Thioesterase
J6E47_RS04640	COG1473	amidohydrolase
J6E47_RS04660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J6E47_RS04660	COG0047	phosphoribosylformylglycinamidine synthase activity
J6E47_RS04665	COG2814	Major facilitator Superfamily
J6E47_RS04675	COG1024	Enoyl-CoA hydratase
J6E47_RS04680	COG1056	cytidyltransferase-related domain
J6E47_RS04680	COG1051	belongs to the nudix hydrolase family
J6E47_RS04690	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
J6E47_RS04705	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
J6E47_RS04720	COG4625	pathogenesis
J6E47_RS04725	COG0583	DNA-binding transcription factor activity
J6E47_RS04730	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
J6E47_RS04735	COG4208	sulfate ABC transporter
J6E47_RS04740	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
J6E47_RS04750	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
J6E47_RS04755	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J6E47_RS04760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
J6E47_RS04780	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J6E47_RS04790	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
J6E47_RS04800	COG0681	Belongs to the peptidase S26 family
J6E47_RS04815	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
J6E47_RS04825	COG1381	Involved in DNA repair and RecF pathway recombination
J6E47_RS04830	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
J6E47_RS04840	COG4221	oxidoreductase activity
J6E47_RS04870	COG0443	Heat shock 70 kDa protein
J6E47_RS04880	COG0436	Aminotransferase
J6E47_RS04900	COG0556	nucleotide-excision repair
J6E47_RS04955	COG2070	2-Nitropropane dioxygenase
J6E47_RS04985	COG1215	transferase activity, transferring glycosyl groups
J6E47_RS05000	COG0415	Belongs to the DNA photolyase family
J6E47_RS05010	COG1252	NADH dehydrogenase
J6E47_RS05015	COG1686	Belongs to the peptidase S11 family
J6E47_RS05030	COG1187	pseudouridine synthase activity
J6E47_RS05100	COG3645	SOS response
J6E47_RS05100	COG3646	Phage regulatory protein
J6E47_RS05280	COG3328	transposase activity
J6E47_RS05380	COG0582	viral genome integration into host DNA
J6E47_RS05405	COG0477	Major facilitator Superfamily
J6E47_RS05410	COG0583	DNA-binding transcription factor activity
J6E47_RS05415	COG1823	symporter activity
J6E47_RS05425	COG0612	Peptidase, M16
J6E47_RS05450	COG0352	thiamine-phosphate diphosphorylase activity
J6E47_RS05485	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6E47_RS05495	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6E47_RS05510	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J6E47_RS05515	COG0076	glutamate decarboxylase activity
J6E47_RS05525	COG1522	sequence-specific DNA binding
J6E47_RS05530	COG3961	Belongs to the TPP enzyme family
J6E47_RS05535	COG1113	amino acid transport
J6E47_RS05540	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
J6E47_RS05545	COG0573	inorganic phosphate transmembrane transporter activity
J6E47_RS05555	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
J6E47_RS05560	COG0616	signal peptide processing
J6E47_RS05595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
J6E47_RS05600	COG1686	Belongs to the peptidase S11 family
J6E47_RS05625	COG0583	DNA-binding transcription factor activity
J6E47_RS05630	COG1067	ATP-dependent peptidase activity
J6E47_RS05655	COG4943	cyclic-guanylate-specific phosphodiesterase activity
J6E47_RS05675	COG1966	Carbon starvation protein
J6E47_RS05680	COG2879	small protein
J6E47_RS05720	COG1335	isochorismatase
J6E47_RS05725	COG0583	DNA-binding transcription factor activity
J6E47_RS05740	COG0596	Alpha beta hydrolase
J6E47_RS05750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J6E47_RS05760	COG2130	NADP-dependent
J6E47_RS05790	COG1741	Belongs to the pirin family
J6E47_RS05800	COG2964	Protein conserved in bacteria
J6E47_RS05815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J6E47_RS05820	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6E47_RS05825	COG4605	iron ion homeostasis
J6E47_RS05830	COG4604	ABC transporter, ATP-binding protein
J6E47_RS05835	COG4607	ABC-type enterochelin transport system periplasmic component
J6E47_RS05840	COG4774	siderophore transport
J6E47_RS05850	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
J6E47_RS05855	COG1021	2,3-dihydroxybenzoate-AMP ligase
J6E47_RS05860	COG1535	isochorismatase
J6E47_RS05860	COG3433	isochorismatase activity
J6E47_RS05875	COG1132	(ABC) transporter
J6E47_RS05880	COG1132	(ABC) transporter
J6E47_RS05885	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
J6E47_RS05895	COG1169	isochorismate synthase
J6E47_RS05910	COG3739	integral membrane protein
J6E47_RS05930	COG0302	gtp cyclohydrolase
J6E47_RS05940	COG1529	Aldehyde oxidase and xanthine dehydrogenase
J6E47_RS05970	COG0308	aminopeptidase N
J6E47_RS05975	COG0512	Glutamine amidotransferase of anthranilate synthase
J6E47_RS05990	COG0174	glutamine synthetase
J6E47_RS06000	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
J6E47_RS06035	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
J6E47_RS06040	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J6E47_RS06045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
J6E47_RS06065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
J6E47_RS06070	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J6E47_RS06075	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J6E47_RS06090	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS06095	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J6E47_RS06100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6E47_RS06110	COG2223	nitrite transmembrane transporter activity
J6E47_RS06120	COG0024	Methionine aminopeptidase
J6E47_RS06125	COG0052	Belongs to the universal ribosomal protein uS2 family
J6E47_RS06140	COG2207	Transcriptional regulator
J6E47_RS06165	COG2951	lytic endotransglycosylase activity
J6E47_RS06170	COG0772	Belongs to the SEDS family
J6E47_RS06185	COG0842	Transport permease protein
J6E47_RS06190	COG1131	(ABC) transporter
J6E47_RS06230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6E47_RS06245	COG4215	(ABC) transporter
J6E47_RS06250	COG4160	amino acid transport
J6E47_RS06255	COG4598	ABC transporter
J6E47_RS06265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6E47_RS06270	COG0826	peptidase U32
J6E47_RS06275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6E47_RS06290	COG1720	tRNA m6t6A37 methyltransferase activity
J6E47_RS06300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6E47_RS06315	COG0642	Histidine kinase
J6E47_RS06325	COG0494	nUDIX hydrolase
J6E47_RS06335	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J6E47_RS06340	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
J6E47_RS06345	COG3139	Protein of unknown function (DUF1315)
J6E47_RS06350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J6E47_RS06355	COG1301	dicarboxylic acid transport
J6E47_RS06360	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS06365	COG2819	hydrolase of the alpha beta superfamily
J6E47_RS06375	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
J6E47_RS06385	COG2195	Cleaves the N-terminal amino acid of tripeptides
J6E47_RS06390	COG1234	tRNA 3'-trailer cleavage
J6E47_RS06420	COG2363	Small membrane protein
J6E47_RS06440	COG0513	Belongs to the DEAD box helicase family
J6E47_RS06450	COG0778	Nitroreductase
J6E47_RS06480	COG1286	toxin biosynthetic process
J6E47_RS06505	COG4783	chaperone-mediated protein folding
J6E47_RS06510	COG1610	YqeY-like protein
J6E47_RS06565	COG2831	hemolysin activation secretion protein
J6E47_RS06685	COG3111	PFAM Bacterial OB fold (BOF) protein
J6E47_RS06710	COG3243	poly(R)-hydroxyalkanoic acid synthase
J6E47_RS06715	COG0786	glutamate:sodium symporter activity
J6E47_RS06725	COG2186	Transcriptional regulator
J6E47_RS06775	COG0477	Major facilitator Superfamily
J6E47_RS06800	COG2985	domain, Protein
J6E47_RS06815	COG2995	paraquat-inducible protein a
J6E47_RS06820	COG3008	intermembrane lipid transfer
J6E47_RS06820	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
J6E47_RS06830	COG2351	hydroxyisourate hydrolase activity
J6E47_RS06870	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J6E47_RS06880	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
J6E47_RS06885	COG0642	Histidine kinase
J6E47_RS06890	COG0745	RESPONSE REGULATOR receiver
J6E47_RS06910	COG1794	racemase activity, acting on amino acids and derivatives
J6E47_RS06940	COG1301	dicarboxylic acid transport
J6E47_RS06950	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6E47_RS06955	COG2011	ABC-type metal ion transport system permease component
J6E47_RS06960	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J6E47_RS06965	COG1464	Belongs to the NlpA lipoprotein family
J6E47_RS06970	COG0151	Belongs to the GarS family
J6E47_RS06975	COG0138	bifunctional purine biosynthesis protein purh
J6E47_RS06980	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
J6E47_RS07010	COG2308	Evidence 4 Homologs of previously reported genes of
J6E47_RS07020	COG1305	Transglutaminase-like
J6E47_RS07030	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J6E47_RS07035	COG0305	Participates in initiation and elongation during chromosome replication
J6E47_RS07060	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
J6E47_RS07070	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
J6E47_RS07075	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
J6E47_RS07100	COG1649	PFAM Uncharacterised BCR, COG1649
J6E47_RS07100	COG0726	polysaccharide deacetylase
J6E47_RS07105	COG1215	transferase activity, transferring glycosyl groups
J6E47_RS07110	COG3658	cytochrome
J6E47_RS07120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J6E47_RS07135	COG0583	DNA-binding transcription factor activity
J6E47_RS07155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J6E47_RS07160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6E47_RS07175	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS07180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6E47_RS07185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6E47_RS07210	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
J6E47_RS07215	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
J6E47_RS07225	COG2205	protein histidine kinase activity
J6E47_RS07230	COG0745	RESPONSE REGULATOR receiver
J6E47_RS07235	COG0174	glutamine synthetase
J6E47_RS07255	COG0729	surface antigen
J6E47_RS07280	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6E47_RS07285	COG2814	Major facilitator Superfamily
J6E47_RS07300	COG0583	DNA-binding transcription factor activity
J6E47_RS07315	COG1187	pseudouridine synthase activity
J6E47_RS07335	COG0802	atpase or kinase
J6E47_RS07340	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
J6E47_RS07350	COG1923	regulation of RNA biosynthetic process
J6E47_RS07355	COG0697	spore germination
J6E47_RS07380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J6E47_RS07385	COG0519	Catalyzes the synthesis of GMP from XMP
J6E47_RS07385	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J6E47_RS07390	COG4302	ethanolamine ammonia-lyase activity
J6E47_RS07395	COG4303	Ethanolamine ammonia lyase large subunit
J6E47_RS07400	COG0531	amino acid
J6E47_RS07420	COG1454	alcohol dehydrogenase
J6E47_RS07425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J6E47_RS07450	COG0308	aminopeptidase N
J6E47_RS07480	COG4221	oxidoreductase activity
J6E47_RS07490	COG1605	Chorismate mutase
J6E47_RS07505	COG1309	transcriptional regulator
J6E47_RS07515	COG0668	transmembrane transport
J6E47_RS07545	COG4773	Receptor
J6E47_RS07565	COG0488	(ABC) transporter
J6E47_RS07570	COG0589	response to stress
J6E47_RS07595	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J6E47_RS07605	COG3135	benzoate transporter
J6E47_RS07610	COG1522	sequence-specific DNA binding
J6E47_RS07620	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J6E47_RS07625	COG0583	DNA-binding transcription factor activity
J6E47_RS07635	COG0183	Belongs to the thiolase family
J6E47_RS07645	COG2030	dehydratase
J6E47_RS07650	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J6E47_RS07665	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J6E47_RS07675	COG0824	Thioesterase
J6E47_RS07680	COG1454	alcohol dehydrogenase
J6E47_RS07690	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J6E47_RS07720	COG0069	glutamate synthase activity
J6E47_RS07805	COG3620	sequence-specific DNA binding
J6E47_RS07995	COG1598	PFAM Uncharacterised protein family UPF0150
J6E47_RS08005	COG0741	lytic transglycosylase activity
J6E47_RS08005	COG1196	nuclear chromosome segregation
J6E47_RS08005	COG0739	heme binding
J6E47_RS08045	COG3179	chitinase
J6E47_RS08055	COG1063	alcohol dehydrogenase
J6E47_RS08060	COG3293	Transposase
J6E47_RS08095	COG2814	Major facilitator Superfamily
J6E47_RS08110	COG0511	ligase activity, forming carbon-carbon bonds
J6E47_RS08130	COG1116	anion transmembrane transporter activity
J6E47_RS08130	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6E47_RS08135	COG0745	RESPONSE REGULATOR receiver
J6E47_RS08145	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6E47_RS08145	COG2146	nitrite reductase [NAD(P)H] activity
J6E47_RS08150	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6E47_RS08155	COG0243	molybdopterin cofactor binding
J6E47_RS08165	COG0243	molybdopterin cofactor binding
J6E47_RS08170	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
J6E47_RS08185	COG0315	cyclic pyranopterin monophosphate synthase activity
J6E47_RS08185	COG0521	Mo-molybdopterin cofactor biosynthetic process
J6E47_RS08200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6E47_RS08205	COG0697	spore germination
J6E47_RS08225	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
J6E47_RS08230	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J6E47_RS08285	COG2204	response regulator
J6E47_RS08290	COG3852	Histidine kinase
J6E47_RS08315	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
J6E47_RS08320	COG0575	Belongs to the CDS family
J6E47_RS08355	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6E47_RS08370	COG2137	regulation of response to DNA damage stimulus
J6E47_RS08380	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
J6E47_RS08385	COG1011	Hydrolase
J6E47_RS08410	COG1522	sequence-specific DNA binding
J6E47_RS08420	COG1113	amino acid transport
J6E47_RS08435	COG0659	secondary active sulfate transmembrane transporter activity
J6E47_RS08440	COG2135	peptidase activity
J6E47_RS08455	COG3300	MHYT domain
J6E47_RS08455	COG5001	Diguanylate cyclase
J6E47_RS08475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6E47_RS08475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
J6E47_RS08475	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
J6E47_RS08480	COG1105	Belongs to the carbohydrate kinase PfkB family
J6E47_RS08485	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J6E47_RS08485	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6E47_RS08515	COG0024	Methionine aminopeptidase
J6E47_RS08520	COG0583	DNA-binding transcription factor activity
J6E47_RS08530	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
J6E47_RS08535	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J6E47_RS08540	COG0516	GMP reductase activity
J6E47_RS08540	COG0517	IMP dehydrogenase activity
J6E47_RS08565	COG0552	protein localization to endoplasmic reticulum
J6E47_RS08575	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
J6E47_RS08590	COG4890	Cyd operon protein YbgT
J6E47_RS08595	COG1294	oxidase, subunit
J6E47_RS08610	COG1585	Membrane protein implicated in regulation of membrane protease activity
J6E47_RS08620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J6E47_RS08625	COG4774	siderophore transport
J6E47_RS08640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J6E47_RS08645	COG0569	domain protein
J6E47_RS08650	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J6E47_RS08680	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
J6E47_RS08685	COG0542	response to heat
J6E47_RS08710	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6E47_RS08710	COG1902	pentaerythritol trinitrate reductase activity
J6E47_RS08755	COG2323	membrane
J6E47_RS08760	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
J6E47_RS08770	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J6E47_RS08775	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J6E47_RS08780	COG0183	Belongs to the thiolase family
J6E47_RS08785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J6E47_RS08790	COG0596	Alpha beta hydrolase
J6E47_RS08795	COG2271	Major facilitator Superfamily
J6E47_RS08800	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J6E47_RS08805	COG3485	protocatechuate 3,4-dioxygenase
J6E47_RS08810	COG3485	protocatechuate 3,4-dioxygenase
J6E47_RS08815	COG0710	3-dehydroquinate dehydratase activity
J6E47_RS08820	COG3420	alginic acid biosynthetic process
J6E47_RS08825	COG3659	wide pore channel activity
J6E47_RS08830	COG4993	Dehydrogenase
J6E47_RS08840	COG2391	methyltransferase activity
J6E47_RS08855	COG1414	Transcriptional regulator
J6E47_RS08860	COG0583	DNA-binding transcription factor activity
J6E47_RS08865	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS08890	COG2814	Major facilitator Superfamily
J6E47_RS08900	COG0154	amidase activity
J6E47_RS08920	COG4638	Rieske (2fe-2S)
J6E47_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS08940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6E47_RS08950	COG3733	amine oxidase
J6E47_RS08960	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS08970	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J6E47_RS08975	COG0183	Belongs to the thiolase family
J6E47_RS08980	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J6E47_RS08985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J6E47_RS08995	COG4829	muconolactone delta-isomerase
J6E47_RS09000	COG4948	Mandelate Racemase Muconate Lactonizing
J6E47_RS09005	COG0583	DNA-binding transcription factor activity
J6E47_RS09015	COG2186	Transcriptional regulator
J6E47_RS09035	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS09050	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6E47_RS09050	COG1902	pentaerythritol trinitrate reductase activity
J6E47_RS09060	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J6E47_RS09095	COG1309	transcriptional regulator
J6E47_RS09100	COG0583	DNA-binding transcription factor activity
J6E47_RS09105	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS09110	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS09115	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS09125	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS09135	COG0318	PFAM AMP-dependent synthetase and ligase
J6E47_RS09220	COG2188	Transcriptional regulator
J6E47_RS09245	COG0583	DNA-binding transcription factor activity
J6E47_RS09280	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6E47_RS09310	COG1566	PFAM secretion protein HlyD family protein
J6E47_RS09325	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS09330	COG0129	dihydroxy-acid dehydratase activity
J6E47_RS09340	COG0583	DNA-binding transcription factor activity
J6E47_RS09345	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J6E47_RS09355	COG2084	Dehydrogenase
J6E47_RS09360	COG2207	Transcriptional regulator
J6E47_RS09375	COG1064	alcohol dehydrogenase
J6E47_RS09385	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
J6E47_RS09390	COG1120	ATPase activity
J6E47_RS09410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J6E47_RS09460	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
J6E47_RS09515	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
J6E47_RS09530	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS09540	COG2207	Transcriptional regulator
J6E47_RS09550	COG2205	protein histidine kinase activity
J6E47_RS09555	COG0745	RESPONSE REGULATOR receiver
J6E47_RS09560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6E47_RS09565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6E47_RS09605	COG3539	Fimbrial protein
J6E47_RS09630	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
J6E47_RS09640	COG0753	catalase activity
J6E47_RS09655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
J6E47_RS09720	COG1535	isochorismatase
J6E47_RS09720	COG3433	isochorismatase activity
J6E47_RS09725	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS09730	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
J6E47_RS09735	COG4149	molybdate abc transporter
J6E47_RS09740	COG0725	ABC transporter, periplasmic molybdate-binding protein
J6E47_RS09750	COG4638	Rieske (2fe-2S)
J6E47_RS09755	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
J6E47_RS09760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6E47_RS09760	COG0543	2 iron, 2 sulfur cluster binding
J6E47_RS09775	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6E47_RS09785	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS09800	COG2207	Transcriptional regulator
J6E47_RS09805	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS09810	COG2610	gluconate transmembrane transporter activity
J6E47_RS09820	COG1309	transcriptional regulator
J6E47_RS09840	COG0583	DNA-binding transcription factor activity
J6E47_RS09855	COG2031	fatty acid transporter
J6E47_RS09860	COG0183	Belongs to the thiolase family
J6E47_RS09865	COG0583	DNA-binding transcription factor activity
J6E47_RS09870	COG0583	DNA-binding transcription factor activity
J6E47_RS09885	COG1027	Aspartate ammonia-lyase
J6E47_RS09895	COG0477	Major facilitator Superfamily
J6E47_RS09915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J6E47_RS09920	COG4521	taurine ABC transporter
J6E47_RS09935	COG2188	Transcriptional regulator
J6E47_RS09945	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
J6E47_RS09950	COG1733	regulation of RNA biosynthetic process
J6E47_RS09955	COG2207	Transcriptional regulator
J6E47_RS09955	COG3708	Transcriptional regulator
J6E47_RS09970	COG0730	response to heat
J6E47_RS09980	COG3453	Protein conserved in bacteria
J6E47_RS09980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6E47_RS09990	COG3781	membrane
J6E47_RS09995	COG1063	alcohol dehydrogenase
J6E47_RS10005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J6E47_RS10010	COG0508	dehydrogenase complex catalyzes the overall conversion of
J6E47_RS10015	COG0022	dehydrogenase e1 component
J6E47_RS10020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
J6E47_RS10025	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
J6E47_RS10040	COG3706	GGDEF domain
J6E47_RS10055	COG0133	tryptophan synthase activity
J6E47_RS10065	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J6E47_RS10100	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
J6E47_RS10125	COG2226	methyltransferase
J6E47_RS10180	COG0842	Transport permease protein
J6E47_RS10185	COG0842	Transport permease protein
J6E47_RS10190	COG1131	(ABC) transporter
J6E47_RS10205	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
J6E47_RS10210	COG4773	Receptor
J6E47_RS10230	COG0730	response to heat
J6E47_RS10235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J6E47_RS10250	COG0406	alpha-ribazole phosphatase activity
J6E47_RS10270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6E47_RS10300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6E47_RS10310	COG4264	IucA IucC family
J6E47_RS10315	COG4264	IucA IucC family
J6E47_RS10335	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J6E47_RS10350	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS10355	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS10360	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
J6E47_RS10365	COG2207	Transcriptional regulator
J6E47_RS10370	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6E47_RS10375	COG0776	regulation of translation
J6E47_RS10400	COG0822	iron-sulfur transferase activity
J6E47_RS10405	COG0316	Belongs to the HesB IscA family
J6E47_RS10435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
J6E47_RS10455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
J6E47_RS10460	COG0702	epimerase
J6E47_RS10495	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J6E47_RS10505	COG0339	signal peptide processing
J6E47_RS10550	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
J6E47_RS10555	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
J6E47_RS10585	COG0776	regulation of translation
J6E47_RS10650	COG0084	hydrolase, TatD family'
J6E47_RS10670	COG1663	tetraacyldisaccharide 4'-kinase activity
J6E47_RS10675	COG1132	(ABC) transporter
J6E47_RS10685	COG0811	peptide transport
J6E47_RS10690	COG1475	DNA binding
J6E47_RS10695	COG1192	Involved in chromosome partitioning
J6E47_RS10705	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J6E47_RS10720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
J6E47_RS10725	COG0191	fructose-bisphosphate aldolase activity
J6E47_RS10745	COG0424	maF-like protein
J6E47_RS10750	COG2850	peptidyl-arginine hydroxylation
J6E47_RS10760	COG0640	Transcriptional regulator
J6E47_RS10770	COG3619	membrane
J6E47_RS10775	COG3122	Protein conserved in bacteria
J6E47_RS10780	COG1132	(ABC) transporter
J6E47_RS10800	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J6E47_RS10805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J6E47_RS10815	COG0506	proline dehydrogenase activity
J6E47_RS10815	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
J6E47_RS10815	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
J6E47_RS10820	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
J6E47_RS10835	COG3698	Phosphodiester glycosidase
J6E47_RS10845	COG2353	YceI-like domain
J6E47_RS10855	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
J6E47_RS10900	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J6E47_RS10900	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J6E47_RS10925	COG3539	Fimbrial protein
J6E47_RS10930	COG3121	Chaperone
J6E47_RS10955	COG0697	spore germination
J6E47_RS10965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J6E47_RS10975	COG0583	DNA-binding transcription factor activity
J6E47_RS10995	COG1309	transcriptional regulator
J6E47_RS11010	COG1522	sequence-specific DNA binding
J6E47_RS11020	COG1126	abc transporter atp-binding protein
J6E47_RS11025	COG0765	amino acid transport
J6E47_RS11030	COG0765	amino acid transport
J6E47_RS11060	COG1464	Belongs to the NlpA lipoprotein family
J6E47_RS11070	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J6E47_RS11075	COG2011	ABC-type metal ion transport system permease component
J6E47_RS11080	COG0012	GTP binding
J6E47_RS11105	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J6E47_RS11145	COG0386	Belongs to the glutathione peroxidase family
J6E47_RS11155	COG0436	Aminotransferase
J6E47_RS11160	COG1301	dicarboxylic acid transport
J6E47_RS11195	COG3634	alkyl hydroperoxide reductase activity
J6E47_RS11210	COG0583	DNA-binding transcription factor activity
J6E47_RS11215	COG0798	PFAM Bile acid sodium symporter
J6E47_RS11220	COG0640	Transcriptional regulator
J6E47_RS11235	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
J6E47_RS11245	COG0583	DNA-binding transcription factor activity
J6E47_RS11255	COG1953	Uracil, thiamine, allantoin
J6E47_RS11265	COG2175	clavaminate synthase activity
J6E47_RS11270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J6E47_RS11275	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
J6E47_RS11280	COG4521	taurine ABC transporter
J6E47_RS11290	COG0477	Major facilitator Superfamily
J6E47_RS11310	COG1271	oxidase subunit
J6E47_RS11315	COG1294	oxidase, subunit
J6E47_RS11325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6E47_RS11345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
J6E47_RS11365	COG3052	prosthetic group binding
J6E47_RS11370	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
J6E47_RS11380	COG0583	DNA-binding transcription factor activity
J6E47_RS11390	COG2814	Major facilitator Superfamily
J6E47_RS11410	COG1346	cytolysis
J6E47_RS11420	COG0583	DNA-binding transcription factor activity
J6E47_RS11425	COG0625	glutathione transferase activity
J6E47_RS11430	COG0625	glutathione transferase activity
J6E47_RS11435	COG0583	DNA-binding transcription factor activity
J6E47_RS11450	COG1045	serine acetyltransferase
J6E47_RS11455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
J6E47_RS11460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
J6E47_RS11465	COG1280	lysine exporter protein (LysE YggA)
J6E47_RS11475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6E47_RS11480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J6E47_RS11490	COG0765	amino acid transport
J6E47_RS11495	COG0765	amino acid transport
J6E47_RS11515	COG0784	Response regulator, receiver
J6E47_RS11515	COG2205	protein histidine kinase activity
J6E47_RS11535	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
J6E47_RS11555	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS11605	COG0583	DNA-binding transcription factor activity
J6E47_RS11625	COG0318	PFAM AMP-dependent synthetase and ligase
J6E47_RS11630	COG1309	transcriptional regulator
J6E47_RS11635	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS11640	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J6E47_RS11645	COG1024	Enoyl-CoA hydratase
J6E47_RS11650	COG4770	biotin carboxylase activity
J6E47_RS11660	COG0583	DNA-binding transcription factor activity
J6E47_RS11675	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS11685	COG2814	Major facilitator Superfamily
J6E47_RS11695	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
J6E47_RS11700	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
J6E47_RS11705	COG2814	Major facilitator Superfamily
J6E47_RS11710	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS11715	COG1024	Enoyl-CoA hydratase
J6E47_RS11720	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS11725	COG1250	3-hydroxyacyl-CoA dehydrogenase
J6E47_RS11730	COG0183	Belongs to the thiolase family
J6E47_RS11740	COG2814	Major facilitator Superfamily
J6E47_RS11750	COG1024	Enoyl-CoA hydratase
J6E47_RS11765	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS11770	COG2814	Major facilitator Superfamily
J6E47_RS11775	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J6E47_RS11780	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
J6E47_RS11800	COG1840	ABC-type Fe3 transport system, periplasmic component
J6E47_RS11810	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6E47_RS11815	COG1414	Transcriptional regulator
J6E47_RS11825	COG0583	DNA-binding transcription factor activity
J6E47_RS11830	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
J6E47_RS11835	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS11845	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
J6E47_RS11855	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS11860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J6E47_RS11865	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6E47_RS11870	COG2267	carboxylic ester hydrolase activity
J6E47_RS11890	COG3038	cytochrome b561
J6E47_RS11895	COG0753	catalase activity
J6E47_RS11900	COG2271	Major facilitator Superfamily
J6E47_RS11905	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J6E47_RS11910	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J6E47_RS11925	COG2207	Transcriptional regulator
J6E47_RS11965	COG2050	protein possibly involved in aromatic compounds catabolism
J6E47_RS11975	COG3327	negative regulation of DNA-templated transcription, initiation
J6E47_RS11980	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
J6E47_RS11985	COG0183	Belongs to the thiolase family
J6E47_RS12005	COG1024	Enoyl-CoA hydratase
J6E47_RS12010	COG1024	Enoyl-CoA hydratase
J6E47_RS12015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6E47_RS12020	COG2151	metal-sulfur cluster biosynthetic enzyme
J6E47_RS12025	COG3396	Phenylacetate-CoA oxygenase
J6E47_RS12030	COG3460	Phenylacetate-CoA oxygenase
J6E47_RS12035	COG3396	Phenylacetate-CoA oxygenase
J6E47_RS12040	COG2030	dehydratase
J6E47_RS12040	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS12045	COG1760	l-serine dehydratase
J6E47_RS12050	COG0531	amino acid
J6E47_RS12055	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS12080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
J6E47_RS12100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6E47_RS12110	COG0789	Transcriptional regulator
J6E47_RS12120	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
J6E47_RS12135	COG2807	transmembrane transport
J6E47_RS12140	COG0590	tRNA wobble adenosine to inosine editing
J6E47_RS12255	COG1116	anion transmembrane transporter activity
J6E47_RS12270	COG0864	Transcriptional regulator
J6E47_RS12280	COG1733	regulation of RNA biosynthetic process
J6E47_RS12285	COG2249	NAD(P)H dehydrogenase (quinone) activity
J6E47_RS12290	COG0439	Biotin carboxylase
J6E47_RS12305	COG1063	alcohol dehydrogenase
J6E47_RS12315	COG1309	transcriptional regulator
J6E47_RS12330	COG3210	domain, Protein
J6E47_RS12335	COG2831	hemolysin activation secretion protein
J6E47_RS12340	COG0038	chloride channel
J6E47_RS12350	COG4770	biotin carboxylase activity
J6E47_RS12370	COG1914	H( )-stimulated, divalent metal cation uptake system
J6E47_RS12375	COG0583	DNA-binding transcription factor activity
J6E47_RS12440	COG1250	3-hydroxyacyl-CoA dehydrogenase
J6E47_RS12460	COG2814	Major facilitator Superfamily
J6E47_RS12470	COG1560	Kdo2-lipid A biosynthetic process
J6E47_RS12480	COG5006	permease, DMT superfamily
J6E47_RS12485	COG1522	sequence-specific DNA binding
J6E47_RS12500	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
J6E47_RS12510	COG4122	O-methyltransferase activity
J6E47_RS12540	COG1538	Outer membrane efflux protein
J6E47_RS12545	COG1137	ATPase activity
J6E47_RS12550	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
J6E47_RS12560	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
J6E47_RS12565	COG0517	IMP dehydrogenase activity
J6E47_RS12565	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J6E47_RS12610	COG2814	Major facilitator Superfamily
J6E47_RS12645	COG1278	Cold shock
J6E47_RS12650	COG1280	lysine exporter protein (LysE YggA)
J6E47_RS12680	COG1570	exodeoxyribonuclease VII activity
J6E47_RS12760	COG2871	sodium ion transport
J6E47_RS12770	COG0583	DNA-binding transcription factor activity
J6E47_RS12775	COG4638	Rieske (2fe-2S)
J6E47_RS12780	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
J6E47_RS12785	COG0633	Ferredoxin
J6E47_RS12785	COG0543	2 iron, 2 sulfur cluster binding
J6E47_RS12790	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS12795	COG3135	benzoate transporter
J6E47_RS12800	COG2814	Major facilitator Superfamily
J6E47_RS12815	COG1643	Atp-dependent helicase
J6E47_RS12820	COG0450	alkyl hydroperoxide reductase
J6E47_RS12830	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
J6E47_RS12840	COG3634	alkyl hydroperoxide reductase activity
J6E47_RS12860	COG0220	tRNA (guanine-N7-)-methyltransferase activity
J6E47_RS12865	COG0625	glutathione transferase activity
J6E47_RS12875	COG2885	chlorophyll binding
J6E47_RS12910	COG0542	response to heat
J6E47_RS12925	COG1765	OsmC-like protein
J6E47_RS12940	COG0667	Aldo Keto reductase
J6E47_RS12955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
J6E47_RS12970	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
J6E47_RS12980	COG0582	viral genome integration into host DNA
J6E47_RS13000	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6E47_RS13065	COG0592	DNA-directed DNA polymerase activity
J6E47_RS13105	COG2026	Addiction module toxin, RelE StbE family
J6E47_RS13255	COG3755	Protein conserved in bacteria
J6E47_RS13305	COG1484	DNA-dependent DNA replication
J6E47_RS13400	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J6E47_RS13440	COG0527	aspartate kinase activity
J6E47_RS13450	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J6E47_RS13460	COG3038	cytochrome b561
J6E47_RS13465	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J6E47_RS13470	COG2252	PERMEase
J6E47_RS13480	COG2072	flavoprotein involved in K transport
J6E47_RS13495	COG1741	Belongs to the pirin family
J6E47_RS13500	COG1309	transcriptional regulator
J6E47_RS13510	COG0300	oxidoreductase activity
J6E47_RS13515	COG2072	flavoprotein involved in K transport
J6E47_RS13520	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
J6E47_RS13565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J6E47_RS13580	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
J6E47_RS13595	COG2814	Major facilitator Superfamily
J6E47_RS13600	COG1024	Enoyl-CoA hydratase
J6E47_RS13605	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS13615	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS13640	COG2186	Transcriptional regulator
J6E47_RS13645	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS13655	COG4948	Mandelate Racemase Muconate Lactonizing
J6E47_RS13660	COG2271	Major facilitator Superfamily
J6E47_RS13665	COG2721	sulfolactate sulfo-lyase activity
J6E47_RS13670	COG0697	spore germination
J6E47_RS13705	COG1113	amino acid transport
J6E47_RS13725	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS13745	COG0531	amino acid
J6E47_RS13755	COG1113	amino acid transport
J6E47_RS13790	COG3209	COG3209 Rhs family protein
J6E47_RS13815	COG4269	membrane
J6E47_RS13830	COG1902	pentaerythritol trinitrate reductase activity
J6E47_RS13830	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6E47_RS13845	COG5001	Diguanylate cyclase
J6E47_RS13845	COG2203	Gaf domain
J6E47_RS13845	COG3706	GGDEF domain
J6E47_RS13845	COG4251	negative regulation of phosphorylation
J6E47_RS13855	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J6E47_RS13875	COG4172	Belongs to the ABC transporter superfamily
J6E47_RS13880	COG4239	(ABC) transporter, permease
J6E47_RS13885	COG4174	ABC transporter (Permease)
J6E47_RS13895	COG1388	LysM domain
J6E47_RS13895	COG0741	lytic transglycosylase activity
J6E47_RS13895	COG1388	LysM domain
J6E47_RS13895	COG0741	lytic transglycosylase activity
J6E47_RS13900	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J6E47_RS13940	COG0583	DNA-binding transcription factor activity
J6E47_RS13945	COG1279	arginine transmembrane transporter activity
J6E47_RS13965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6E47_RS13970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
J6E47_RS13975	COG0006	proline dipeptidase activity
J6E47_RS14010	COG2194	sulfuric ester hydrolase activity
J6E47_RS14060	COG0739	heme binding
J6E47_RS14075	COG1598	PFAM Uncharacterised protein family UPF0150
J6E47_RS14235	COG0270	DNA (cytosine-5-)-methyltransferase activity
J6E47_RS14325	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J6E47_RS14350	COG3384	dioxygenase
J6E47_RS14360	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J6E47_RS14365	COG2878	Part of a membrane complex involved in electron transport
J6E47_RS14370	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J6E47_RS14395	COG0768	penicillin binding
J6E47_RS14400	COG0742	ribosomal rna small subunit methyltransferase
J6E47_RS14415	COG0830	nickel cation binding
J6E47_RS14460	COG1253	flavin adenine dinucleotide binding
J6E47_RS14465	COG2851	Citrate transporter
J6E47_RS14515	COG1773	rubredoxin
J6E47_RS14520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
J6E47_RS14530	COG0583	DNA-binding transcription factor activity
J6E47_RS14560	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
J6E47_RS14565	COG4181	ATPase activity
J6E47_RS14610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
J6E47_RS14630	COG0306	phosphate transporter
J6E47_RS14640	COG3958	Transketolase
J6E47_RS14645	COG3959	Transketolase, thiamine diphosphate binding domain
J6E47_RS14650	COG2271	Major facilitator Superfamily
J6E47_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS14660	COG0583	DNA-binding transcription factor activity
J6E47_RS14675	COG2223	nitrite transmembrane transporter activity
J6E47_RS14680	COG2207	Transcriptional regulator
J6E47_RS14685	COG2066	Belongs to the glutaminase family
J6E47_RS14690	COG0242	peptide deformylase activity
J6E47_RS14695	COG0477	Major facilitator Superfamily
J6E47_RS14705	COG0028	Belongs to the TPP enzyme family
J6E47_RS14720	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS14725	COG2267	carboxylic ester hydrolase activity
J6E47_RS14735	COG2271	Major facilitator Superfamily
J6E47_RS14740	COG0446	pyridine nucleotide-disulphide oxidoreductase
J6E47_RS14750	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS14770	COG1414	Transcriptional regulator
J6E47_RS14785	COG1024	Enoyl-CoA hydratase
J6E47_RS14795	COG1215	transferase activity, transferring glycosyl groups
J6E47_RS14800	COG0726	polysaccharide deacetylase
J6E47_RS14800	COG1649	PFAM Uncharacterised BCR, COG1649
J6E47_RS14810	COG4681	YaeQ
J6E47_RS14820	COG0523	cobalamin synthesis protein
J6E47_RS14830	COG1607	acyl-coa hydrolase
J6E47_RS14840	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6E47_RS14845	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
J6E47_RS14850	COG1309	transcriptional regulator
J6E47_RS14875	COG2040	homocysteine
J6E47_RS14880	COG0531	amino acid
J6E47_RS14935	COG1595	DNA-templated transcription, initiation
J6E47_RS14945	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6E47_RS14950	COG0477	Major facilitator Superfamily
J6E47_RS15010	COG0405	Gamma-glutamyltransferase
J6E47_RS15015	COG2814	Major facilitator Superfamily
J6E47_RS15025	COG2050	protein possibly involved in aromatic compounds catabolism
J6E47_RS15040	COG1090	epimerase
J6E47_RS15060	COG0420	3'-5' exonuclease activity
J6E47_RS15085	COG0735	belongs to the Fur family
J6E47_RS15090	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
J6E47_RS15110	COG0121	glutamine amidotransferase
J6E47_RS15125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J6E47_RS15135	COG0210	DNA helicase
J6E47_RS15140	COG2885	chlorophyll binding
J6E47_RS15145	COG0204	Acyl-transferase
J6E47_RS15160	COG2894	cell division
J6E47_RS15175	COG1280	lysine exporter protein (LysE YggA)
J6E47_RS15180	COG1674	ftsk spoiiie
J6E47_RS15180	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
J6E47_RS15185	COG0492	ferredoxin-NADP+ reductase activity
J6E47_RS15190	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
J6E47_RS15200	COG0456	acetyltransferase
J6E47_RS15245	COG1981	membrane
J6E47_RS15260	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
J6E47_RS15260	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J6E47_RS15280	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS15290	COG0657	acetylesterase activity
J6E47_RS15300	COG0473	3-isopropylmalate dehydrogenase activity
J6E47_RS15305	COG0583	DNA-binding transcription factor activity
J6E47_RS15325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6E47_RS15350	COG0564	pseudouridine synthase activity
J6E47_RS15360	COG0358	DNA primase activity
J6E47_RS15375	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
J6E47_RS15405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
J6E47_RS15435	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
J6E47_RS15445	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J6E47_RS15445	COG0351	phosphomethylpyrimidine kinase
J6E47_RS15445	COG0352	thiamine-phosphate diphosphorylase activity
J6E47_RS15450	COG1652	LysM domain
J6E47_RS15475	COG1399	metal-binding, possibly nucleic acid-binding protein
J6E47_RS15480	COG3101	peptidyl-lysine hydroxylation
J6E47_RS15485	COG0009	L-threonylcarbamoyladenylate synthase
J6E47_RS15490	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
J6E47_RS15495	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
J6E47_RS15510	COG4106	trans-aconitate 2-methyltransferase activity
J6E47_RS15525	COG0596	Alpha beta hydrolase
J6E47_RS15525	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J6E47_RS15525	COG2226	methyltransferase
J6E47_RS15530	COG1877	trehalose-phosphatase activity
J6E47_RS15535	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
J6E47_RS15540	COG2223	nitrite transmembrane transporter activity
J6E47_RS15560	COG1196	nuclear chromosome segregation
J6E47_RS15570	COG0730	response to heat
J6E47_RS15585	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
J6E47_RS15595	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J6E47_RS15650	COG0489	protein tyrosine kinase activity
J6E47_RS15660	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6E47_RS15660	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6E47_RS15690	COG2515	1-aminocyclopropane-1-carboxylate deaminase
J6E47_RS15695	COG2081	HI0933 family
J6E47_RS15705	COG0668	transmembrane transport
J6E47_RS15725	COG0583	DNA-binding transcription factor activity
J6E47_RS15750	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
J6E47_RS15755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J6E47_RS15785	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
J6E47_RS15825	COG0745	RESPONSE REGULATOR receiver
J6E47_RS15845	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
J6E47_RS15850	COG0697	spore germination
J6E47_RS15885	COG0477	Major facilitator Superfamily
J6E47_RS15895	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS15940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
J6E47_RS15975	COG0583	DNA-binding transcription factor activity
J6E47_RS15990	COG0583	DNA-binding transcription factor activity
J6E47_RS15995	COG1053	succinate dehydrogenase
J6E47_RS16005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
J6E47_RS16010	COG2814	Major facilitator Superfamily
J6E47_RS16015	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS16020	COG0583	DNA-binding transcription factor activity
J6E47_RS16025	COG1063	alcohol dehydrogenase
J6E47_RS16055	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
J6E47_RS16060	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
J6E47_RS16065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J6E47_RS16085	COG2132	Multicopper oxidase
J6E47_RS16095	COG0561	phosphatase activity
J6E47_RS16100	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J6E47_RS16110	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J6E47_RS16125	COG1214	PFAM Peptidase M22, glycoprotease
J6E47_RS16185	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
J6E47_RS16195	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
J6E47_RS16200	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
J6E47_RS16205	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J6E47_RS16265	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
J6E47_RS16275	COG1846	Transcriptional regulator
J6E47_RS16280	COG1764	response to oxidative stress
J6E47_RS16320	COG0037	tRNA processing
J6E47_RS16330	COG0248	Ppx GppA phosphatase
J6E47_RS16360	COG0072	phenylalanine-tRNA ligase activity
J6E47_RS16400	COG1238	metal cluster binding
J6E47_RS16405	COG0625	glutathione transferase activity
J6E47_RS16420	COG0318	PFAM AMP-dependent synthetase and ligase
J6E47_RS16425	COG3028	Belongs to the UPF0307 family
J6E47_RS16430	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
J6E47_RS16450	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
J6E47_RS16455	COG0617	tRNA 3'-terminal CCA addition
J6E47_RS16460	COG1555	photosystem II stabilization
J6E47_RS16465	COG3956	TIGRFAM MazG family protein
J6E47_RS16475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J6E47_RS16495	COG0784	Response regulator, receiver
J6E47_RS16495	COG2205	protein histidine kinase activity
J6E47_RS16495	COG5002	protein histidine kinase activity
J6E47_RS16500	COG1024	Enoyl-CoA hydratase
J6E47_RS16505	COG2084	Dehydrogenase
J6E47_RS16510	COG3622	Belongs to the hyi family
J6E47_RS16540	COG0697	spore germination
J6E47_RS16550	COG2814	Major facilitator Superfamily
J6E47_RS16570	COG2132	Multicopper oxidase
J6E47_RS16585	COG2205	protein histidine kinase activity
J6E47_RS16675	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
J6E47_RS16685	COG0583	DNA-binding transcription factor activity
J6E47_RS16695	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
J6E47_RS16705	COG0084	hydrolase, TatD family'
J6E47_RS16720	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
J6E47_RS16755	COG0440	acetolactate synthase activity
J6E47_RS16760	COG0028	Belongs to the TPP enzyme family
J6E47_RS16785	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
J6E47_RS16790	COG1136	(ABC) transporter
J6E47_RS16790	COG0577	efflux transmembrane transporter activity
J6E47_RS16795	COG1538	Outer membrane efflux protein
J6E47_RS16810	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
J6E47_RS16815	COG1162	GTPase activity
J6E47_RS16825	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J6E47_RS16865	COG1426	Protein conserved in bacteria
J6E47_RS16900	COG0793	Belongs to the peptidase S41A family
J6E47_RS16915	COG2267	carboxylic ester hydrolase activity
J6E47_RS16925	COG1012	belongs to the aldehyde dehydrogenase family
J6E47_RS16930	COG3265	gluconokinase activity
J6E47_RS16940	COG0800	Aldolase
J6E47_RS16950	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J6E47_RS16955	COG0857	belongs to the CobB CobQ family
J6E47_RS16955	COG0280	phosphate acetyltransferase
J6E47_RS16960	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
J6E47_RS16960	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
J6E47_RS16980	COG0740	serine-type endopeptidase activity
J6E47_RS16990	COG4774	siderophore transport
J6E47_RS17000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
J6E47_RS17010	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
J6E47_RS17010	COG2813	Specifically methylates the guanine in position
J6E47_RS17110	COG0788	formyltetrahydrofolate deformylase activity
J6E47_RS17135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J6E47_RS17135	COG4651	solute:proton antiporter activity
J6E47_RS17155	COG0724	RNA recognition motif
J6E47_RS17160	COG0210	DNA helicase
J6E47_RS17185	COG1733	regulation of RNA biosynthetic process
J6E47_RS17195	COG2900	Belongs to the SlyX family
J6E47_RS17200	COG0488	(ABC) transporter
J6E47_RS17205	COG1280	lysine exporter protein (LysE YggA)
J6E47_RS17210	COG1560	Kdo2-lipid A biosynthetic process
J6E47_RS17220	COG1301	dicarboxylic acid transport
J6E47_RS17275	COG0473	3-isopropylmalate dehydrogenase activity
J6E47_RS17360	COG0625	glutathione transferase activity
J6E47_RS17365	COG2378	regulation of single-species biofilm formation
J6E47_RS17370	COG0546	phosphoglycolate phosphatase activity
J6E47_RS17380	COG1530	ribonuclease E activity
J6E47_RS17385	COG0318	PFAM AMP-dependent synthetase and ligase
J6E47_RS17400	COG0583	DNA-binding transcription factor activity
J6E47_RS17405	COG4221	oxidoreductase activity
J6E47_RS17410	COG0635	Involved in the biosynthesis of porphyrin-containing compound
J6E47_RS17420	COG0534	Mate efflux family protein
J6E47_RS17435	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
J6E47_RS17460	COG0493	'glutamate synthase
J6E47_RS17460	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
J6E47_RS17470	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
J6E47_RS17475	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
J6E47_RS17490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
J6E47_RS17500	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
J6E47_RS17500	COG0644	oxidoreductase
J6E47_RS17510	COG0425	Belongs to the sulfur carrier protein TusA family
J6E47_RS17515	COG4535	Mg2 and Co2 transporter CorC
J6E47_RS17525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
J6E47_RS17545	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J6E47_RS17550	COG0475	glutathione-regulated potassium exporter activity
J6E47_RS17550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J6E47_RS17565	COG0484	heat shock protein binding
J6E47_RS17570	COG0789	Transcriptional regulator
J6E47_RS17575	COG0598	Magnesium transport protein CorA
J6E47_RS17590	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
J6E47_RS17595	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J6E47_RS17600	COG1074	ATP-dependent DNA helicase activity
J6E47_RS17605	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
J6E47_RS17625	COG2226	methyltransferase
J6E47_RS17645	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
J6E47_RS17660	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
J6E47_RS17660	COG2111	Na H antiporter
J6E47_RS17665	COG1006	Multisubunit Na H antiporter MnhC subunit
J6E47_RS17670	COG0651	ATP synthesis coupled electron transport
J6E47_RS17675	COG1863	multisubunit Na H antiporter MnhE subunit
J6E47_RS17680	COG2212	antiporter activity
J6E47_RS17685	COG1320	monovalent cation:proton antiporter activity
J6E47_RS17700	COG0195	Participates in both transcription termination and antitermination
J6E47_RS17750	COG0237	dephospho-CoA kinase activity
J6E47_RS17760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J6E47_RS17775	COG0497	DNA recombination
J6E47_RS17785	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
J6E47_RS17815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J6E47_RS17815	COG2169	Transcriptional regulator
J6E47_RS17820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J6E47_RS17885	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
J6E47_RS17900	COG0326	Molecular chaperone. Has ATPase activity
J6E47_RS17915	COG2056	Na+-H+ antiporter family
J6E47_RS17920	COG0596	Alpha beta hydrolase
J6E47_RS18015	COG0546	phosphoglycolate phosphatase activity
J6E47_RS18020	COG1716	ATPase activity
J6E47_RS18065	COG0181	hydroxymethylbilane synthase activity
J6E47_RS18075	COG3275	phosphorelay sensor kinase activity
J6E47_RS18095	COG1538	Outer membrane efflux protein
J6E47_RS18100	COG0697	spore germination
J6E47_RS18125	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
J6E47_RS18130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
J6E47_RS18135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
J6E47_RS18140	COG0772	Belongs to the SEDS family
J6E47_RS18165	COG4974	Belongs to the 'phage' integrase family
J6E47_RS18170	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6E47_RS18180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
J6E47_RS18190	COG2197	response regulator
J6E47_RS18205	COG0793	Belongs to the peptidase S41A family
J6E47_RS18210	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
J6E47_RS18215	COG0795	lipopolysaccharide-transporting ATPase activity
J6E47_RS18255	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J6E47_RS18255	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
J6E47_RS18265	COG0004	ammonium transporteR
J6E47_RS18270	COG0347	Belongs to the P(II) protein family
J6E47_RS18280	COG0606	chelatase, subunit chli
J6E47_RS18320	COG0659	secondary active sulfate transmembrane transporter activity
J6E47_RS18325	COG0589	response to stress
J6E47_RS18365	COG0606	chelatase, subunit chli
J6E47_RS18370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J6E47_RS18380	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
J6E47_RS18395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J6E47_RS18410	COG0318	PFAM AMP-dependent synthetase and ligase
J6E47_RS18420	COG0477	Major facilitator Superfamily
J6E47_RS18425	COG2860	membrane
J6E47_RS18435	COG1253	flavin adenine dinucleotide binding
J6E47_RS18455	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6E47_RS18490	COG0655	NAD(P)H dehydrogenase (quinone) activity
J6E47_RS18500	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
J6E47_RS18570	COG0758	DNA mediated transformation
J6E47_RS18580	COG0697	spore germination
J6E47_RS18585	COG1309	transcriptional regulator
J6E47_RS18600	COG0386	Belongs to the glutathione peroxidase family
J6E47_RS18665	COG1121	(ABC) transporter
J6E47_RS18670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
J6E47_RS18675	COG1280	lysine exporter protein (LysE YggA)
J6E47_RS18680	COG2837	iron assimilation
J6E47_RS18685	COG0281	malic enzyme
J6E47_RS18730	COG0518	GMP synthase (glutamine-hydrolyzing) activity
J6E47_RS18730	COG0519	Catalyzes the synthesis of GMP from XMP
J6E47_RS18735	COG4399	Belongs to the UPF0754 family
J6E47_RS18740	COG2259	Doxx family
J6E47_RS18745	COG0586	Pfam SNARE associated Golgi protein
J6E47_RS18760	COG1192	Involved in chromosome partitioning
J6E47_RS18770	COG0271	Belongs to the BolA IbaG family
J6E47_RS18790	COG2267	carboxylic ester hydrolase activity
J6E47_RS18810	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
J6E47_RS18810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
J6E47_RS18810	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
J6E47_RS18810	COG3321	synthase
J6E47_RS18815	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS18825	COG2197	response regulator
J6E47_RS18835	COG3916	Acyl-homoserine-lactone synthase
J6E47_RS18840	COG0477	Major facilitator Superfamily
J6E47_RS18845	COG1024	Enoyl-CoA hydratase
J6E47_RS18850	COG1024	Enoyl-CoA hydratase
J6E47_RS18855	COG1960	acyl-CoA dehydrogenase activity
J6E47_RS18860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
J6E47_RS18880	COG1113	amino acid transport
J6E47_RS18885	COG1113	amino acid transport
J6E47_RS18890	COG0251	oxidation-reduction process
J6E47_RS18930	COG0564	pseudouridine synthase activity
J6E47_RS18945	COG3328	transposase activity
J6E47_RS18975	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J6E47_RS18990	COG1802	Transcriptional regulator
J6E47_RS19000	COG1448	Aminotransferase
J6E47_RS19005	COG0277	FAD linked oxidase domain protein
J6E47_RS19015	COG2186	Transcriptional regulator
J6E47_RS19025	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
J6E47_RS19030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J6E47_RS19045	COG1210	Utp--glucose-1-phosphate uridylyltransferase
J6E47_RS19060	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J6E47_RS19075	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J6E47_RS19110	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS19120	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS19125	COG1083	cytidylyl-transferase
J6E47_RS19130	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
J6E47_RS19140	COG2089	acid synthase
J6E47_RS19145	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
J6E47_RS19150	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
J6E47_RS19160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
J6E47_RS19190	COG0728	peptidoglycan biosynthetic process
J6E47_RS19195	COG3023	N-Acetylmuramoyl-L-alanine amidase
J6E47_RS19250	COG0546	phosphoglycolate phosphatase activity
J6E47_RS19255	COG1028	Short-chain dehydrogenase reductase Sdr
J6E47_RS19275	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6E47_RS19280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J6E47_RS19285	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
J6E47_RS19290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J6E47_RS19295	COG1116	anion transmembrane transporter activity
J6E47_RS19300	COG1309	transcriptional regulator
J6E47_RS19305	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J6E47_RS19315	COG0196	riboflavin kinase activity
J6E47_RS19320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
J6E47_RS19330	COG1047	Peptidyl-prolyl cis-trans
J6E47_RS19370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J6E47_RS19375	COG0657	acetylesterase activity
J6E47_RS19425	COG2951	lytic endotransglycosylase activity
J6E47_RS19430	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J6E47_RS19445	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
J6E47_RS19455	COG0671	phosphoesterase, PA-phosphatase related
J6E47_RS19460	COG0861	Integral membrane protein TerC family
J6E47_RS19470	COG0754	glutathionylspermidine amidase activity
J6E47_RS19480	COG0402	S-adenosylhomocysteine deaminase activity
J6E47_RS19495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6E47_RS19500	COG1230	cation diffusion facilitator family transporter
J6E47_RS19515	COG0706	membrane insertase activity
J6E47_RS19550	COG3173	Aminoglycoside phosphotransferase
J6E47_RS19555	COG0488	(ABC) transporter
J6E47_RS19570	COG0482	sulfurtransferase activity
J6E47_RS19720	COG1192	Involved in chromosome partitioning
J6E47_RS19750	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
J6E47_RS19755	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
J6E47_RS19795	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J6E47_RS19940	COG0583	DNA-binding transcription factor activity
J6E47_RS19965	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
J6E47_RS19975	COG0659	secondary active sulfate transmembrane transporter activity
J6E47_RS20035	COG1373	ATPase (AAA superfamily
J6E47_RS20075	COG1309	transcriptional regulator
J6E47_RS20100	COG0633	Ferredoxin
J6E47_RS20105	COG2207	Transcriptional regulator
J6E47_RS20260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
J6E47_RS20310	COG1192	Involved in chromosome partitioning
J6E47_RS20320	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6E47_RS20360	COG0739	heme binding
J6E47_RS20590	COG0501	Belongs to the peptidase M48B family
J6E47_RS20625	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
J6E47_RS20690	COG2826	transposase and inactivated derivatives, IS30 family
J6E47_RS20700	COG2826	transposase and inactivated derivatives, IS30 family
J6E47_RS20725	COG0741	lytic transglycosylase activity
J6E47_RS20760	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
J6E47_RS20845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J6E47_RS20915	COG1525	nuclease
J6E47_RS20975	COG1475	DNA binding
J6E47_RS20990	COG3853	Toxic anion resistance protein (TelA)
J6E47_RS21090	COG4683	PFAM Phage derived protein Gp49-like (DUF891)