locus-tag	class	description
H1D55_RS00010	COG1024	Enoyl-CoA hydratase
H1D55_RS00015	COG2814	Major facilitator Superfamily
H1D55_RS00030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1D55_RS00075	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
H1D55_RS00080	COG2072	flavoprotein involved in K transport
H1D55_RS00085	COG0300	oxidoreductase activity
H1D55_RS00095	COG1309	transcriptional regulator
H1D55_RS00100	COG1741	Belongs to the pirin family
H1D55_RS00115	COG2072	flavoprotein involved in K transport
H1D55_RS00125	COG2252	PERMEase
H1D55_RS00130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H1D55_RS00135	COG3038	cytochrome b561
H1D55_RS00145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H1D55_RS00155	COG0527	aspartate kinase activity
H1D55_RS00165	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H1D55_RS00175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H1D55_RS00190	COG0667	Aldo Keto reductase
H1D55_RS00205	COG1765	OsmC-like protein
H1D55_RS00220	COG0542	response to heat
H1D55_RS00255	COG2885	chlorophyll binding
H1D55_RS00265	COG0625	glutathione transferase activity
H1D55_RS00285	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H1D55_RS00305	COG3634	alkyl hydroperoxide reductase activity
H1D55_RS00315	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H1D55_RS00325	COG0450	alkyl hydroperoxide reductase
H1D55_RS00330	COG1643	Atp-dependent helicase
H1D55_RS00345	COG2814	Major facilitator Superfamily
H1D55_RS00350	COG3135	benzoate transporter
H1D55_RS00355	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS00360	COG0633	Ferredoxin
H1D55_RS00360	COG0543	2 iron, 2 sulfur cluster binding
H1D55_RS00365	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1D55_RS00370	COG4638	Rieske (2fe-2S)
H1D55_RS00380	COG0583	DNA-binding transcription factor activity
H1D55_RS00430	COG1570	exodeoxyribonuclease VII activity
H1D55_RS00460	COG1280	lysine exporter protein (LysE YggA)
H1D55_RS00465	COG1278	Cold shock
H1D55_RS00500	COG2814	Major facilitator Superfamily
H1D55_RS00560	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
H1D55_RS00560	COG0517	IMP dehydrogenase activity
H1D55_RS00565	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H1D55_RS00575	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H1D55_RS00580	COG1137	ATPase activity
H1D55_RS00585	COG1538	Outer membrane efflux protein
H1D55_RS00615	COG4122	O-methyltransferase activity
H1D55_RS00625	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H1D55_RS00640	COG1522	sequence-specific DNA binding
H1D55_RS00655	COG1560	Kdo2-lipid A biosynthetic process
H1D55_RS00670	COG2814	Major facilitator Superfamily
H1D55_RS00690	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1D55_RS00725	COG0583	DNA-binding transcription factor activity
H1D55_RS00730	COG1914	H( )-stimulated, divalent metal cation uptake system
H1D55_RS00750	COG4770	biotin carboxylase activity
H1D55_RS00755	COG0038	chloride channel
H1D55_RS00760	COG2831	hemolysin activation secretion protein
H1D55_RS00765	COG3210	domain, Protein
H1D55_RS00780	COG1309	transcriptional regulator
H1D55_RS00790	COG1063	alcohol dehydrogenase
H1D55_RS00805	COG0439	Biotin carboxylase
H1D55_RS00810	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1D55_RS00815	COG1733	regulation of RNA biosynthetic process
H1D55_RS00830	COG0864	Transcriptional regulator
H1D55_RS00840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1D55_RS00845	COG1116	anion transmembrane transporter activity
H1D55_RS00965	COG0590	tRNA wobble adenosine to inosine editing
H1D55_RS00970	COG2807	transmembrane transport
H1D55_RS00985	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H1D55_RS00995	COG0789	Transcriptional regulator
H1D55_RS01005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1D55_RS01050	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS01055	COG0531	amino acid
H1D55_RS01060	COG1760	l-serine dehydratase
H1D55_RS01065	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS01065	COG2030	dehydratase
H1D55_RS01070	COG3396	Phenylacetate-CoA oxygenase
H1D55_RS01075	COG3460	Phenylacetate-CoA oxygenase
H1D55_RS01080	COG3396	Phenylacetate-CoA oxygenase
H1D55_RS01085	COG2151	metal-sulfur cluster biosynthetic enzyme
H1D55_RS01090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1D55_RS01095	COG1024	Enoyl-CoA hydratase
H1D55_RS01100	COG1024	Enoyl-CoA hydratase
H1D55_RS01105	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1D55_RS01110	COG0183	Belongs to the thiolase family
H1D55_RS01115	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H1D55_RS01120	COG3327	negative regulation of DNA-templated transcription, initiation
H1D55_RS01130	COG2050	protein possibly involved in aromatic compounds catabolism
H1D55_RS01180	COG2207	Transcriptional regulator
H1D55_RS01195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1D55_RS01200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1D55_RS01205	COG2271	Major facilitator Superfamily
H1D55_RS01210	COG0753	catalase activity
H1D55_RS01215	COG3038	cytochrome b561
H1D55_RS01235	COG2267	carboxylic ester hydrolase activity
H1D55_RS01240	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1D55_RS01245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1D55_RS01250	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS01260	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1D55_RS01270	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS01275	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1D55_RS01280	COG0583	DNA-binding transcription factor activity
H1D55_RS01290	COG1414	Transcriptional regulator
H1D55_RS01295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1D55_RS01305	COG1840	ABC-type Fe3 transport system, periplasmic component
H1D55_RS01310	COG3842	ATPase activity
H1D55_RS01325	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H1D55_RS01330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1D55_RS01335	COG2814	Major facilitator Superfamily
H1D55_RS01340	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS01355	COG1024	Enoyl-CoA hydratase
H1D55_RS01365	COG2814	Major facilitator Superfamily
H1D55_RS01375	COG0183	Belongs to the thiolase family
H1D55_RS01380	COG1250	3-hydroxyacyl-CoA dehydrogenase
H1D55_RS01385	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS01390	COG1024	Enoyl-CoA hydratase
H1D55_RS01395	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS01400	COG2814	Major facilitator Superfamily
H1D55_RS01405	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1D55_RS01410	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1D55_RS01420	COG2814	Major facilitator Superfamily
H1D55_RS01430	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS01445	COG0583	DNA-binding transcription factor activity
H1D55_RS01455	COG4770	biotin carboxylase activity
H1D55_RS01460	COG1024	Enoyl-CoA hydratase
H1D55_RS01465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1D55_RS01470	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS01475	COG1309	transcriptional regulator
H1D55_RS01480	COG0318	PFAM AMP-dependent synthetase and ligase
H1D55_RS01500	COG0583	DNA-binding transcription factor activity
H1D55_RS01550	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS01575	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
H1D55_RS01595	COG0784	Response regulator, receiver
H1D55_RS01595	COG2205	protein histidine kinase activity
H1D55_RS01615	COG0765	amino acid transport
H1D55_RS01620	COG0765	amino acid transport
H1D55_RS01625	COG1126	abc transporter atp-binding protein
H1D55_RS01630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H1D55_RS01650	COG1280	lysine exporter protein (LysE YggA)
H1D55_RS01655	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H1D55_RS01660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1D55_RS01665	COG1045	serine acetyltransferase
H1D55_RS01680	COG0583	DNA-binding transcription factor activity
H1D55_RS01685	COG0625	glutathione transferase activity
H1D55_RS01690	COG0625	glutathione transferase activity
H1D55_RS01695	COG0583	DNA-binding transcription factor activity
H1D55_RS01705	COG1346	cytolysis
H1D55_RS01725	COG2814	Major facilitator Superfamily
H1D55_RS01735	COG0583	DNA-binding transcription factor activity
H1D55_RS01750	COG3052	prosthetic group binding
H1D55_RS01790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1D55_RS01800	COG1294	oxidase, subunit
H1D55_RS01805	COG1271	oxidase subunit
H1D55_RS01835	COG4521	taurine ABC transporter
H1D55_RS01840	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H1D55_RS01845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1D55_RS01850	COG2175	clavaminate synthase activity
H1D55_RS01860	COG1953	Uracil, thiamine, allantoin
H1D55_RS01870	COG0583	DNA-binding transcription factor activity
H1D55_RS01880	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H1D55_RS01895	COG0640	Transcriptional regulator
H1D55_RS01900	COG0798	PFAM Bile acid sodium symporter
H1D55_RS01905	COG0583	DNA-binding transcription factor activity
H1D55_RS01920	COG3634	alkyl hydroperoxide reductase activity
H1D55_RS01960	COG0436	Aminotransferase
H1D55_RS01970	COG0386	Belongs to the glutathione peroxidase family
H1D55_RS02010	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1D55_RS02035	COG0012	GTP binding
H1D55_RS02040	COG2011	ABC-type metal ion transport system permease component
H1D55_RS02045	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1D55_RS02055	COG1464	Belongs to the NlpA lipoprotein family
H1D55_RS02085	COG0765	amino acid transport
H1D55_RS02090	COG0765	amino acid transport
H1D55_RS02095	COG1126	abc transporter atp-binding protein
H1D55_RS02105	COG1522	sequence-specific DNA binding
H1D55_RS02120	COG1309	transcriptional regulator
H1D55_RS02140	COG0583	DNA-binding transcription factor activity
H1D55_RS02150	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H1D55_RS02160	COG0697	spore germination
H1D55_RS02185	COG3121	Chaperone
H1D55_RS02190	COG3539	Fimbrial protein
H1D55_RS02215	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H1D55_RS02215	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H1D55_RS02260	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H1D55_RS02270	COG2353	YceI-like domain
H1D55_RS02280	COG3698	Phosphodiester glycosidase
H1D55_RS02300	COG0506	proline dehydrogenase activity
H1D55_RS02300	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1D55_RS02300	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H1D55_RS02310	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1D55_RS02315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H1D55_RS02335	COG1132	(ABC) transporter
H1D55_RS02340	COG3122	Protein conserved in bacteria
H1D55_RS02345	COG3619	membrane
H1D55_RS02355	COG0640	Transcriptional regulator
H1D55_RS02365	COG2850	peptidyl-arginine hydroxylation
H1D55_RS02370	COG0424	maF-like protein
H1D55_RS02390	COG0191	fructose-bisphosphate aldolase activity
H1D55_RS02395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1D55_RS02410	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H1D55_RS02420	COG1192	Involved in chromosome partitioning
H1D55_RS02425	COG1475	DNA binding
H1D55_RS02430	COG0811	peptide transport
H1D55_RS02440	COG1132	(ABC) transporter
H1D55_RS02445	COG1663	tetraacyldisaccharide 4'-kinase activity
H1D55_RS02465	COG0084	hydrolase, TatD family'
H1D55_RS02530	COG0776	regulation of translation
H1D55_RS02560	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H1D55_RS02565	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H1D55_RS02595	COG4206	TonB-dependent receptor
H1D55_RS02615	COG0339	signal peptide processing
H1D55_RS02625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H1D55_RS02660	COG0702	epimerase
H1D55_RS02665	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1D55_RS02685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1D55_RS02715	COG0316	Belongs to the HesB IscA family
H1D55_RS02720	COG0822	iron-sulfur transferase activity
H1D55_RS02745	COG0776	regulation of translation
H1D55_RS02750	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H1D55_RS02755	COG2207	Transcriptional regulator
H1D55_RS02760	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D55_RS02765	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS02770	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS02785	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H1D55_RS02810	COG4264	IucA IucC family
H1D55_RS02820	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H1D55_RS02850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H1D55_RS02870	COG0406	alpha-ribazole phosphatase activity
H1D55_RS02885	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H1D55_RS02890	COG0730	response to heat
H1D55_RS02910	COG4773	Receptor
H1D55_RS02915	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1D55_RS02930	COG1131	(ABC) transporter
H1D55_RS02935	COG0842	Transport permease protein
H1D55_RS02940	COG0842	Transport permease protein
H1D55_RS02995	COG2226	methyltransferase
H1D55_RS03020	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H1D55_RS03055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1D55_RS03065	COG0133	tryptophan synthase activity
H1D55_RS03080	COG3706	GGDEF domain
H1D55_RS03095	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1D55_RS03100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H1D55_RS03105	COG0022	dehydrogenase e1 component
H1D55_RS03110	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1D55_RS03115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1D55_RS03125	COG1063	alcohol dehydrogenase
H1D55_RS03130	COG3781	membrane
H1D55_RS03140	COG3453	Protein conserved in bacteria
H1D55_RS03140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1D55_RS03155	COG0730	response to heat
H1D55_RS03170	COG3708	Transcriptional regulator
H1D55_RS03170	COG2207	Transcriptional regulator
H1D55_RS03175	COG1733	regulation of RNA biosynthetic process
H1D55_RS03180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H1D55_RS03190	COG2188	Transcriptional regulator
H1D55_RS03205	COG4521	taurine ABC transporter
H1D55_RS03210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1D55_RS03230	COG0477	Major facilitator Superfamily
H1D55_RS03240	COG1027	Aspartate ammonia-lyase
H1D55_RS03255	COG0583	DNA-binding transcription factor activity
H1D55_RS03260	COG0583	DNA-binding transcription factor activity
H1D55_RS03265	COG0183	Belongs to the thiolase family
H1D55_RS03270	COG2031	fatty acid transporter
H1D55_RS03285	COG0583	DNA-binding transcription factor activity
H1D55_RS03305	COG1309	transcriptional regulator
H1D55_RS03315	COG2610	gluconate transmembrane transporter activity
H1D55_RS03320	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS03325	COG2207	Transcriptional regulator
H1D55_RS03340	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS03350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1D55_RS03365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1D55_RS03365	COG0543	2 iron, 2 sulfur cluster binding
H1D55_RS03370	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H1D55_RS03375	COG4638	Rieske (2fe-2S)
H1D55_RS03385	COG0725	ABC transporter, periplasmic molybdate-binding protein
H1D55_RS03390	COG4149	molybdate abc transporter
H1D55_RS03395	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H1D55_RS03400	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS03405	COG3433	isochorismatase activity
H1D55_RS03405	COG1535	isochorismatase
H1D55_RS03465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1D55_RS03480	COG0753	catalase activity
H1D55_RS03490	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H1D55_RS03515	COG3539	Fimbrial protein
H1D55_RS03600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H1D55_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D55_RS03610	COG0745	RESPONSE REGULATOR receiver
H1D55_RS03615	COG2205	protein histidine kinase activity
H1D55_RS03625	COG2207	Transcriptional regulator
H1D55_RS03640	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS03655	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
H1D55_RS03705	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H1D55_RS03770	COG1401	restriction endodeoxyribonuclease activity
H1D55_RS03815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1D55_RS03835	COG1120	ATPase activity
H1D55_RS03840	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D55_RS03850	COG1064	alcohol dehydrogenase
H1D55_RS03865	COG2207	Transcriptional regulator
H1D55_RS03870	COG2084	Dehydrogenase
H1D55_RS03880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H1D55_RS03885	COG0583	DNA-binding transcription factor activity
H1D55_RS03895	COG0129	dihydroxy-acid dehydratase activity
H1D55_RS03900	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS03915	COG1566	PFAM secretion protein HlyD family protein
H1D55_RS03930	COG0583	DNA-binding transcription factor activity
H1D55_RS03945	COG2188	Transcriptional regulator
H1D55_RS03980	COG3210	domain, Protein
H1D55_RS03985	COG2831	hemolysin activation secretion protein
H1D55_RS04000	COG0318	PFAM AMP-dependent synthetase and ligase
H1D55_RS04010	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS04020	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS04025	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS04030	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS04035	COG0583	DNA-binding transcription factor activity
H1D55_RS04040	COG1309	transcriptional regulator
H1D55_RS04080	COG1902	pentaerythritol trinitrate reductase activity
H1D55_RS04080	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1D55_RS04095	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS04115	COG2186	Transcriptional regulator
H1D55_RS04125	COG0583	DNA-binding transcription factor activity
H1D55_RS04130	COG4948	Mandelate Racemase Muconate Lactonizing
H1D55_RS04135	COG4829	muconolactone delta-isomerase
H1D55_RS04145	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1D55_RS04150	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1D55_RS04155	COG0183	Belongs to the thiolase family
H1D55_RS04160	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1D55_RS04170	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS04180	COG3733	amine oxidase
H1D55_RS04190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1D55_RS04200	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS04210	COG4638	Rieske (2fe-2S)
H1D55_RS04230	COG0154	amidase activity
H1D55_RS04240	COG2814	Major facilitator Superfamily
H1D55_RS04265	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS04270	COG0583	DNA-binding transcription factor activity
H1D55_RS04275	COG1414	Transcriptional regulator
H1D55_RS04290	COG2391	methyltransferase activity
H1D55_RS04300	COG4993	Dehydrogenase
H1D55_RS04305	COG3659	wide pore channel activity
H1D55_RS04310	COG3420	alginic acid biosynthetic process
H1D55_RS04315	COG0710	3-dehydroquinate dehydratase activity
H1D55_RS04320	COG3485	protocatechuate 3,4-dioxygenase
H1D55_RS04325	COG3485	protocatechuate 3,4-dioxygenase
H1D55_RS04330	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H1D55_RS04335	COG2271	Major facilitator Superfamily
H1D55_RS04340	COG0596	Alpha beta hydrolase
H1D55_RS04345	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H1D55_RS04350	COG0183	Belongs to the thiolase family
H1D55_RS04355	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H1D55_RS04360	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H1D55_RS04370	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H1D55_RS04375	COG2323	membrane
H1D55_RS04420	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1D55_RS04420	COG1902	pentaerythritol trinitrate reductase activity
H1D55_RS04445	COG0542	response to heat
H1D55_RS04450	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H1D55_RS04480	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1D55_RS04485	COG0569	domain protein
H1D55_RS04490	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H1D55_RS04505	COG4774	siderophore transport
H1D55_RS04510	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H1D55_RS04520	COG1585	Membrane protein implicated in regulation of membrane protease activity
H1D55_RS04535	COG1294	oxidase, subunit
H1D55_RS04540	COG4890	Cyd operon protein YbgT
H1D55_RS04550	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H1D55_RS04560	COG0552	protein localization to endoplasmic reticulum
H1D55_RS04585	COG0516	GMP reductase activity
H1D55_RS04585	COG0517	IMP dehydrogenase activity
H1D55_RS04590	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1D55_RS04595	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H1D55_RS04605	COG0583	DNA-binding transcription factor activity
H1D55_RS04610	COG0024	Methionine aminopeptidase
H1D55_RS04640	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H1D55_RS04640	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D55_RS04645	COG1105	Belongs to the carbohydrate kinase PfkB family
H1D55_RS04650	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H1D55_RS04650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1D55_RS04650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H1D55_RS04670	COG3300	MHYT domain
H1D55_RS04670	COG5001	Diguanylate cyclase
H1D55_RS04685	COG2135	peptidase activity
H1D55_RS04690	COG0659	secondary active sulfate transmembrane transporter activity
H1D55_RS04710	COG1113	amino acid transport
H1D55_RS04720	COG1522	sequence-specific DNA binding
H1D55_RS04745	COG1011	Hydrolase
H1D55_RS04750	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H1D55_RS04760	COG2137	regulation of response to DNA damage stimulus
H1D55_RS04775	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1D55_RS04810	COG0575	Belongs to the CDS family
H1D55_RS04815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H1D55_RS04840	COG3852	Histidine kinase
H1D55_RS04845	COG2204	response regulator
H1D55_RS04900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1D55_RS04905	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H1D55_RS04925	COG0697	spore germination
H1D55_RS04930	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1D55_RS04940	COG0303	'Molybdopterin
H1D55_RS04945	COG0315	cyclic pyranopterin monophosphate synthase activity
H1D55_RS04945	COG0521	Mo-molybdopterin cofactor biosynthetic process
H1D55_RS04960	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H1D55_RS04965	COG0243	molybdopterin cofactor binding
H1D55_RS04975	COG0243	molybdopterin cofactor binding
H1D55_RS04980	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1D55_RS04985	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1D55_RS04985	COG2146	nitrite reductase [NAD(P)H] activity
H1D55_RS04995	COG0745	RESPONSE REGULATOR receiver
H1D55_RS05000	COG1116	anion transmembrane transporter activity
H1D55_RS05000	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1D55_RS05020	COG0511	ligase activity, forming carbon-carbon bonds
H1D55_RS05035	COG2814	Major facilitator Superfamily
H1D55_RS05055	COG0069	glutamate synthase activity
H1D55_RS05075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H1D55_RS05085	COG1454	alcohol dehydrogenase
H1D55_RS05090	COG0824	Thioesterase
H1D55_RS05105	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H1D55_RS05125	COG2030	dehydratase
H1D55_RS05135	COG0183	Belongs to the thiolase family
H1D55_RS05145	COG0583	DNA-binding transcription factor activity
H1D55_RS05150	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H1D55_RS05160	COG1522	sequence-specific DNA binding
H1D55_RS05165	COG3135	benzoate transporter
H1D55_RS05175	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H1D55_RS05200	COG0589	response to stress
H1D55_RS05205	COG0488	(ABC) transporter
H1D55_RS05225	COG4773	Receptor
H1D55_RS05255	COG0668	transmembrane transport
H1D55_RS05265	COG1309	transcriptional regulator
H1D55_RS05285	COG1605	Chorismate mutase
H1D55_RS05325	COG0308	aminopeptidase N
H1D55_RS05350	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1D55_RS05355	COG1454	alcohol dehydrogenase
H1D55_RS05375	COG0531	amino acid
H1D55_RS05380	COG4303	Ethanolamine ammonia lyase large subunit
H1D55_RS05385	COG4302	ethanolamine ammonia-lyase activity
H1D55_RS05390	COG0519	Catalyzes the synthesis of GMP from XMP
H1D55_RS05390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1D55_RS05395	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1D55_RS05405	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H1D55_RS05420	COG0697	spore germination
H1D55_RS05425	COG1923	regulation of RNA biosynthetic process
H1D55_RS05435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H1D55_RS05440	COG0802	atpase or kinase
H1D55_RS05460	COG1187	pseudouridine synthase activity
H1D55_RS05475	COG0583	DNA-binding transcription factor activity
H1D55_RS05490	COG2814	Major facilitator Superfamily
H1D55_RS05495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H1D55_RS05520	COG0729	surface antigen
H1D55_RS05540	COG0174	glutamine synthetase
H1D55_RS05545	COG0745	RESPONSE REGULATOR receiver
H1D55_RS05550	COG2205	protein histidine kinase activity
H1D55_RS05560	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H1D55_RS05565	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H1D55_RS05590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1D55_RS05595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1D55_RS05600	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS05630	COG0583	DNA-binding transcription factor activity
H1D55_RS05645	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1D55_RS05655	COG3658	cytochrome
H1D55_RS05660	COG1215	transferase activity, transferring glycosyl groups
H1D55_RS05665	COG1649	PFAM Uncharacterised BCR, COG1649
H1D55_RS05665	COG0726	polysaccharide deacetylase
H1D55_RS05690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H1D55_RS05695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H1D55_RS05705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H1D55_RS05730	COG0305	Participates in initiation and elongation during chromosome replication
H1D55_RS05735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H1D55_RS05745	COG1305	Transglutaminase-like
H1D55_RS05755	COG2308	Evidence 4 Homologs of previously reported genes of
H1D55_RS05785	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H1D55_RS05790	COG0138	bifunctional purine biosynthesis protein purh
H1D55_RS05795	COG0151	Belongs to the GarS family
H1D55_RS05800	COG1464	Belongs to the NlpA lipoprotein family
H1D55_RS05805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1D55_RS05810	COG2011	ABC-type metal ion transport system permease component
H1D55_RS05815	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1D55_RS05825	COG1301	dicarboxylic acid transport
H1D55_RS05855	COG1794	racemase activity, acting on amino acids and derivatives
H1D55_RS05875	COG0745	RESPONSE REGULATOR receiver
H1D55_RS05880	COG0642	Histidine kinase
H1D55_RS05885	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H1D55_RS05895	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H1D55_RS05935	COG2351	hydroxyisourate hydrolase activity
H1D55_RS05945	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H1D55_RS05945	COG3008	intermembrane lipid transfer
H1D55_RS05950	COG2995	paraquat-inducible protein a
H1D55_RS05985	COG1051	belongs to the nudix hydrolase family
H1D55_RS05990	COG0477	Major facilitator Superfamily
H1D55_RS06040	COG2186	Transcriptional regulator
H1D55_RS06050	COG0786	glutamate:sodium symporter activity
H1D55_RS06055	COG3243	poly(R)-hydroxyalkanoic acid synthase
H1D55_RS06080	COG3111	PFAM Bacterial OB fold (BOF) protein
H1D55_RS06180	COG1610	YqeY-like protein
H1D55_RS06185	COG4783	chaperone-mediated protein folding
H1D55_RS06210	COG1286	toxin biosynthetic process
H1D55_RS06240	COG0778	Nitroreductase
H1D55_RS06250	COG0513	Belongs to the DEAD box helicase family
H1D55_RS06275	COG2363	Small membrane protein
H1D55_RS06305	COG1234	tRNA 3'-trailer cleavage
H1D55_RS06310	COG2195	Cleaves the N-terminal amino acid of tripeptides
H1D55_RS06320	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H1D55_RS06330	COG2819	hydrolase of the alpha beta superfamily
H1D55_RS06335	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS06340	COG1301	dicarboxylic acid transport
H1D55_RS06345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H1D55_RS06350	COG3139	Protein of unknown function (DUF1315)
H1D55_RS06355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H1D55_RS06360	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H1D55_RS06370	COG0494	nUDIX hydrolase
H1D55_RS06380	COG0642	Histidine kinase
H1D55_RS06390	COG3111	PFAM Bacterial OB fold (BOF) protein
H1D55_RS06395	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H1D55_RS06405	COG1720	tRNA m6t6A37 methyltransferase activity
H1D55_RS06420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1D55_RS06425	COG0826	peptidase U32
H1D55_RS06430	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1D55_RS06440	COG4598	ABC transporter
H1D55_RS06445	COG4160	amino acid transport
H1D55_RS06450	COG4215	(ABC) transporter
H1D55_RS06465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D55_RS06510	COG1131	(ABC) transporter
H1D55_RS06515	COG0842	Transport permease protein
H1D55_RS06530	COG0772	Belongs to the SEDS family
H1D55_RS06535	COG2951	lytic endotransglycosylase activity
H1D55_RS06560	COG2207	Transcriptional regulator
H1D55_RS06575	COG0052	Belongs to the universal ribosomal protein uS2 family
H1D55_RS06580	COG0024	Methionine aminopeptidase
H1D55_RS06590	COG2223	nitrite transmembrane transporter activity
H1D55_RS06600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1D55_RS06605	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H1D55_RS06610	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS06625	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H1D55_RS06630	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H1D55_RS06635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1D55_RS06655	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1D55_RS06660	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H1D55_RS06665	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H1D55_RS06700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H1D55_RS06710	COG0174	glutamine synthetase
H1D55_RS06725	COG0512	Glutamine amidotransferase of anthranilate synthase
H1D55_RS06730	COG0308	aminopeptidase N
H1D55_RS06760	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H1D55_RS06770	COG0302	gtp cyclohydrolase
H1D55_RS06790	COG3739	integral membrane protein
H1D55_RS06805	COG1169	isochorismate synthase
H1D55_RS06815	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H1D55_RS06820	COG1132	(ABC) transporter
H1D55_RS06825	COG1132	(ABC) transporter
H1D55_RS06835	COG3433	isochorismatase activity
H1D55_RS06835	COG1535	isochorismatase
H1D55_RS06840	COG1021	2,3-dihydroxybenzoate-AMP ligase
H1D55_RS06845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1D55_RS06855	COG4774	siderophore transport
H1D55_RS06860	COG4607	ABC-type enterochelin transport system periplasmic component
H1D55_RS06865	COG4604	ABC transporter, ATP-binding protein
H1D55_RS06870	COG4605	iron ion homeostasis
H1D55_RS06875	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H1D55_RS06880	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1D55_RS06895	COG2964	Protein conserved in bacteria
H1D55_RS06905	COG1741	Belongs to the pirin family
H1D55_RS06940	COG2879	small protein
H1D55_RS06945	COG1966	Carbon starvation protein
H1D55_RS06965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H1D55_RS06990	COG1067	ATP-dependent peptidase activity
H1D55_RS06995	COG0583	DNA-binding transcription factor activity
H1D55_RS07020	COG1686	Belongs to the peptidase S11 family
H1D55_RS07025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H1D55_RS07060	COG0616	signal peptide processing
H1D55_RS07065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H1D55_RS07075	COG0573	inorganic phosphate transmembrane transporter activity
H1D55_RS07080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H1D55_RS07085	COG1113	amino acid transport
H1D55_RS07090	COG3961	Belongs to the TPP enzyme family
H1D55_RS07095	COG1522	sequence-specific DNA binding
H1D55_RS07105	COG0076	glutamate decarboxylase activity
H1D55_RS07110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1D55_RS07125	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1D55_RS07135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1D55_RS07170	COG0352	thiamine-phosphate diphosphorylase activity
H1D55_RS07195	COG0612	Peptidase, M16
H1D55_RS07205	COG1823	symporter activity
H1D55_RS07210	COG0583	DNA-binding transcription factor activity
H1D55_RS07215	COG0477	Major facilitator Superfamily
H1D55_RS07240	COG1187	pseudouridine synthase activity
H1D55_RS07255	COG1686	Belongs to the peptidase S11 family
H1D55_RS07260	COG1252	NADH dehydrogenase
H1D55_RS07270	COG0415	Belongs to the DNA photolyase family
H1D55_RS07285	COG1215	transferase activity, transferring glycosyl groups
H1D55_RS07315	COG2070	2-Nitropropane dioxygenase
H1D55_RS07370	COG0556	nucleotide-excision repair
H1D55_RS07390	COG0436	Aminotransferase
H1D55_RS07400	COG0443	Heat shock 70 kDa protein
H1D55_RS07430	COG4221	oxidoreductase activity
H1D55_RS07440	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H1D55_RS07445	COG1381	Involved in DNA repair and RecF pathway recombination
H1D55_RS07455	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H1D55_RS07470	COG0681	Belongs to the peptidase S26 family
H1D55_RS07485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H1D55_RS07505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H1D55_RS07510	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H1D55_RS07515	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H1D55_RS07525	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H1D55_RS07530	COG4208	sulfate ABC transporter
H1D55_RS07535	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H1D55_RS07540	COG0583	DNA-binding transcription factor activity
H1D55_RS07545	COG4625	pathogenesis
H1D55_RS07560	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H1D55_RS07575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H1D55_RS07585	COG1056	cytidyltransferase-related domain
H1D55_RS07585	COG1051	belongs to the nudix hydrolase family
H1D55_RS07590	COG1024	Enoyl-CoA hydratase
H1D55_RS07600	COG2814	Major facilitator Superfamily
H1D55_RS07605	COG0047	phosphoribosylformylglycinamidine synthase activity
H1D55_RS07605	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H1D55_RS07625	COG1473	amidohydrolase
H1D55_RS07630	COG0824	Thioesterase
H1D55_RS07650	COG0823	Involved in the tonB-independent uptake of proteins
H1D55_RS07670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1D55_RS07705	COG0628	permease
H1D55_RS07715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H1D55_RS07720	COG0596	Alpha beta hydrolase
H1D55_RS07725	COG0616	signal peptide processing
H1D55_RS07725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H1D55_RS07735	COG0658	competence protein
H1D55_RS07735	COG2333	competence protein COMEC
H1D55_RS07740	COG1136	(ABC) transporter
H1D55_RS07745	COG4591	ABC-type transport system involved in lipoprotein release permease component
H1D55_RS07780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D55_RS07800	COG0463	Glycosyl transferase, family 2
H1D55_RS07830	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1D55_RS07835	COG1280	lysine exporter protein (LysE YggA)
H1D55_RS07840	COG2267	carboxylic ester hydrolase activity
H1D55_RS07855	COG0019	diaminopimelate decarboxylase activity
H1D55_RS07865	COG1113	amino acid transport
H1D55_RS07880	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H1D55_RS07890	COG3339	Conserved Protein
H1D55_RS07895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H1D55_RS07900	COG0243	molybdopterin cofactor binding
H1D55_RS07905	COG1929	Belongs to the glycerate kinase type-1 family
H1D55_RS07920	COG0778	Nitroreductase
H1D55_RS07945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1D55_RS07960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H1D55_RS07980	COG0741	lytic transglycosylase activity
H1D55_RS08000	COG0584	glycerophosphoryl diester phosphodiesterase
H1D55_RS08005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1D55_RS08030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1D55_RS08035	COG1597	lipid kinase activity
H1D55_RS08050	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H1D55_RS08055	COG0477	Major facilitator Superfamily
H1D55_RS08105	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H1D55_RS08110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H1D55_RS08135	COG0505	Belongs to the CarA family
H1D55_RS08155	COG0589	response to stress
H1D55_RS08170	COG2843	Capsule synthesis protein
H1D55_RS08190	COG2321	neutral zinc metallopeptidase
H1D55_RS08195	COG2354	Protein conserved in bacteria
H1D55_RS08215	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H1D55_RS08240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H1D55_RS08245	COG1053	succinate dehydrogenase
H1D55_RS08250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H1D55_RS08255	COG2009	succinate dehydrogenase
H1D55_RS08290	COG2921	Belongs to the UPF0250 family
H1D55_RS08295	COG0321	lipoyl(octanoyl) transferase activity
H1D55_RS08310	COG0531	amino acid
H1D55_RS08325	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H1D55_RS08330	COG1648	precorrin-2 dehydrogenase activity
H1D55_RS08330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H1D55_RS08345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H1D55_RS08375	COG0671	phosphoesterase, PA-phosphatase related
H1D55_RS08380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D55_RS08390	COG1538	Outer membrane efflux protein
H1D55_RS08395	COG0393	Putative heavy-metal-binding
H1D55_RS08400	COG0393	Putative heavy-metal-binding
H1D55_RS08410	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS08420	COG0525	valine-tRNA ligase activity
H1D55_RS08440	COG0583	DNA-binding transcription factor activity
H1D55_RS08445	COG0004	ammonium transporteR
H1D55_RS08460	COG0642	Histidine kinase
H1D55_RS08465	COG0745	RESPONSE REGULATOR receiver
H1D55_RS08470	COG2194	sulfuric ester hydrolase activity
H1D55_RS08490	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1D55_RS08505	COG2315	Protein conserved in bacteria
H1D55_RS08510	COG0142	geranyltranstransferase activity
H1D55_RS08515	COG2828	Protein conserved in bacteria
H1D55_RS08520	COG1113	amino acid transport
H1D55_RS08540	COG2207	Transcriptional regulator
H1D55_RS08565	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1D55_RS08575	COG0560	Phosphoserine phosphatase
H1D55_RS08585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H1D55_RS08595	COG1530	ribonuclease E activity
H1D55_RS08600	COG0424	maF-like protein
H1D55_RS08605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H1D55_RS08610	COG1792	Involved in formation and maintenance of cell shape
H1D55_RS08615	COG1077	Cell shape determining protein MreB Mrl
H1D55_RS08620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1D55_RS08630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H1D55_RS08655	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H1D55_RS08660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H1D55_RS08665	COG1752	Esterase of the alpha-beta hydrolase superfamily
H1D55_RS08670	COG1115	amino acid carrier protein
H1D55_RS08690	COG2814	Major facilitator Superfamily
H1D55_RS08695	COG1289	transmembrane transporter activity
H1D55_RS08705	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H1D55_RS08745	COG1376	ErfK ybiS ycfS ynhG family protein
H1D55_RS08750	COG2832	Protein of unknown function (DUF454)
H1D55_RS08760	COG5510	response to toxic substance
H1D55_RS08780	COG0840	transmembrane signaling receptor activity
H1D55_RS08820	COG3422	double-strand break repair
H1D55_RS08825	COG2824	Alkylphosphonate utilization operon protein PhnA
H1D55_RS08830	COG3189	MarR family transcriptional regulator
H1D55_RS08840	COG0354	folic acid binding
H1D55_RS08845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1D55_RS08855	COG0679	Auxin Efflux Carrier
H1D55_RS08860	COG1902	pentaerythritol trinitrate reductase activity
H1D55_RS08865	COG4772	TonB-dependent receptor
H1D55_RS08870	COG2094	Belongs to the DNA glycosylase MPG family
H1D55_RS08895	COG1217	gtp-binding protein TYPA
H1D55_RS08900	COG2233	PERMEase
H1D55_RS08910	COG0833	amino acid
H1D55_RS08915	COG1690	Belongs to the RtcB family
H1D55_RS08925	COG2885	chlorophyll binding
H1D55_RS08925	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H1D55_RS08935	COG0183	Belongs to the thiolase family
H1D55_RS08955	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1D55_RS08975	COG2207	Transcriptional regulator
H1D55_RS08980	COG0183	Belongs to the thiolase family
H1D55_RS09010	COG1272	protein, Hemolysin III
H1D55_RS09015	COG0477	Major facilitator Superfamily
H1D55_RS09030	COG0450	alkyl hydroperoxide reductase
H1D55_RS09050	COG0285	dihydrofolate synthase activity
H1D55_RS09095	COG4206	TonB-dependent receptor
H1D55_RS09100	COG2096	Adenosyltransferase
H1D55_RS09120	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H1D55_RS09125	COG0745	RESPONSE REGULATOR receiver
H1D55_RS09130	COG2205	protein histidine kinase activity
H1D55_RS09140	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS09145	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS09150	COG0583	DNA-binding transcription factor activity
H1D55_RS09155	COG0625	glutathione transferase activity
H1D55_RS09220	COG0438	transferase activity, transferring glycosyl groups
H1D55_RS09225	COG0463	Glycosyl transferase, family 2
H1D55_RS09230	COG0726	polysaccharide deacetylase
H1D55_RS09250	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H1D55_RS09255	COG2205	protein histidine kinase activity
H1D55_RS09355	COG0582	viral genome integration into host DNA
H1D55_RS09390	COG1862	Preprotein translocase
H1D55_RS09400	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H1D55_RS09405	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H1D55_RS09415	COG3781	membrane
H1D55_RS09420	COG0613	PHP domain protein
H1D55_RS09430	COG2350	Protein conserved in bacteria
H1D55_RS09460	COG1607	acyl-coa hydrolase
H1D55_RS09520	COG2199	diguanylate cyclase activity
H1D55_RS09530	COG1408	metallophosphoesterase
H1D55_RS09535	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H1D55_RS09545	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H1D55_RS09565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H1D55_RS09570	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H1D55_RS09585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H1D55_RS09595	COG2969	positive regulation of protein catabolic process
H1D55_RS09615	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS09620	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H1D55_RS09635	COG1309	transcriptional regulator
H1D55_RS09640	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS09685	COG1183	phosphatidylcholine synthase activity
H1D55_RS09690	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H1D55_RS09720	COG0739	heme binding
H1D55_RS09720	COG1196	nuclear chromosome segregation
H1D55_RS09720	COG0741	lytic transglycosylase activity
H1D55_RS09730	COG1702	phosphate starvation-inducible protein PhoH
H1D55_RS09765	COG1295	ribonuclease BN
H1D55_RS09770	COG0697	spore germination
H1D55_RS09775	COG2169	Transcriptional regulator
H1D55_RS09780	COG0179	Fumarylacetoacetate (FAA) hydrolase
H1D55_RS09825	COG0557	exoribonuclease II activity
H1D55_RS09830	COG0339	signal peptide processing
H1D55_RS09835	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H1D55_RS09865	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H1D55_RS09870	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS10025	COG0626	cystathionine gamma-synthase activity
H1D55_RS10030	COG0433	COG0433 Predicted ATPase
H1D55_RS10035	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H1D55_RS10035	COG1017	nitric oxide dioxygenase activity
H1D55_RS10040	COG1959	2 iron, 2 sulfur cluster binding
H1D55_RS10055	COG1301	dicarboxylic acid transport
H1D55_RS10060	COG1946	Acyl-CoA thioesterase
H1D55_RS10080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H1D55_RS10085	COG1040	competence protein
H1D55_RS10090	COG0494	nUDIX hydrolase
H1D55_RS10100	COG0598	Magnesium transport protein CorA
H1D55_RS10110	COG2854	intermembrane phospholipid transfer
H1D55_RS10120	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H1D55_RS10125	COG1127	ABC transporter
H1D55_RS10135	COG0513	Belongs to the DEAD box helicase family
H1D55_RS10155	COG0408	coproporphyrinogen oxidase activity
H1D55_RS10170	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS10180	COG1983	PspC domain protein
H1D55_RS10185	COG0517	IMP dehydrogenase activity
H1D55_RS10225	COG0583	DNA-binding transcription factor activity
H1D55_RS10265	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS10275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H1D55_RS10280	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1D55_RS10285	COG0833	amino acid
H1D55_RS10315	COG1192	Involved in chromosome partitioning
H1D55_RS10320	COG0628	permease
H1D55_RS10330	COG1289	transmembrane transporter activity
H1D55_RS10345	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1D55_RS10350	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H1D55_RS10360	COG0277	FAD linked oxidase domain protein
H1D55_RS10365	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H1D55_RS10390	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H1D55_RS10395	COG5380	lipid catabolic process
H1D55_RS10415	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H1D55_RS10465	COG0194	GDP metabolic process
H1D55_RS10480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1D55_RS10500	COG3307	-O-antigen
H1D55_RS10520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H1D55_RS10525	COG1704	LemA family
H1D55_RS10535	COG0493	'glutamate synthase
H1D55_RS10540	COG0067	glutamate synthase
H1D55_RS10540	COG0069	glutamate synthase activity
H1D55_RS10540	COG0070	glutamate synthase
H1D55_RS10590	COG2226	methyltransferase
H1D55_RS10605	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H1D55_RS10610	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H1D55_RS10655	COG0833	amino acid
H1D55_RS10720	COG0488	(ABC) transporter
H1D55_RS10725	COG2873	o-acetylhomoserine
H1D55_RS10730	COG4221	oxidoreductase activity
H1D55_RS10735	COG0659	secondary active sulfate transmembrane transporter activity
H1D55_RS10760	COG0427	acetyl-CoA hydrolase
H1D55_RS10790	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H1D55_RS10830	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H1D55_RS10900	COG2249	NAD(P)H dehydrogenase (quinone) activity
H1D55_RS10905	COG1733	regulation of RNA biosynthetic process
H1D55_RS10935	COG0667	Aldo Keto reductase
H1D55_RS10955	COG0583	DNA-binding transcription factor activity
H1D55_RS10960	COG2814	Major facilitator Superfamily
H1D55_RS10990	COG1335	isochorismatase
H1D55_RS11000	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS11005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H1D55_RS11015	COG1113	amino acid transport
H1D55_RS11025	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H1D55_RS11040	COG2814	Major facilitator Superfamily
H1D55_RS11050	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1D55_RS11050	COG0352	thiamine-phosphate diphosphorylase activity
H1D55_RS11050	COG0351	phosphomethylpyrimidine kinase
H1D55_RS11070	COG1309	transcriptional regulator
H1D55_RS11075	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H1D55_RS11090	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1D55_RS11100	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H1D55_RS11105	COG3162	membrane
H1D55_RS11110	COG0784	Response regulator, receiver
H1D55_RS11110	COG2198	Histidine kinase
H1D55_RS11110	COG2205	protein histidine kinase activity
H1D55_RS11135	COG1522	sequence-specific DNA binding
H1D55_RS11140	COG1335	isochorismatase
H1D55_RS11145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1D55_RS11155	COG0668	transmembrane transport
H1D55_RS11160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H1D55_RS11165	COG1519	Transferase
H1D55_RS11170	COG1902	pentaerythritol trinitrate reductase activity
H1D55_RS11190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H1D55_RS11215	COG0426	domain, Protein
H1D55_RS11215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1D55_RS11220	COG4774	siderophore transport
H1D55_RS11225	COG2119	membrane
H1D55_RS11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
H1D55_RS11245	COG4942	peptidase
H1D55_RS11260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H1D55_RS11270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H1D55_RS11290	COG0189	ligase activity
H1D55_RS11310	COG0708	Exodeoxyribonuclease III
H1D55_RS11315	COG1393	Belongs to the ArsC family
H1D55_RS11330	COG3706	GGDEF domain
H1D55_RS11365	COG2351	hydroxyisourate hydrolase activity
H1D55_RS11370	COG2233	PERMEase
H1D55_RS11380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1D55_RS11390	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H1D55_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS11405	COG3150	esterase
H1D55_RS11420	COG3179	chitinase
H1D55_RS11435	COG2918	glutathione biosynthetic process
H1D55_RS11450	COG2733	membrane
H1D55_RS11455	COG0436	Aminotransferase
H1D55_RS11460	COG0534	Mate efflux family protein
H1D55_RS11510	COG0753	catalase activity
H1D55_RS11555	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H1D55_RS11560	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H1D55_RS11570	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H1D55_RS11575	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1D55_RS11580	COG0546	phosphoglycolate phosphatase activity
H1D55_RS11590	COG0010	Belongs to the arginase family
H1D55_RS11620	COG2188	Transcriptional regulator
H1D55_RS11630	COG0523	cobalamin synthesis protein
H1D55_RS11640	COG1113	amino acid transport
H1D55_RS11650	COG0625	glutathione transferase activity
H1D55_RS11670	COG1683	Conserved Protein
H1D55_RS11680	COG0385	Bile acid
H1D55_RS11685	COG1335	isochorismatase
H1D55_RS11690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1D55_RS11710	COG2116	formate transmembrane transporter activity
H1D55_RS11715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H1D55_RS11720	COG2133	pyrroloquinoline quinone binding
H1D55_RS11725	COG2983	Belongs to the UPF0260 family
H1D55_RS11745	COG1194	a g-specific adenine glycosylase
H1D55_RS11760	COG2818	Glycosylase
H1D55_RS11765	COG1064	alcohol dehydrogenase
H1D55_RS11770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H1D55_RS11785	COG0583	DNA-binding transcription factor activity
H1D55_RS11790	COG0656	L-ascorbic acid biosynthetic process
H1D55_RS11795	COG2814	Major facilitator Superfamily
H1D55_RS11830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D55_RS11845	COG2233	PERMEase
H1D55_RS11850	COG0583	DNA-binding transcription factor activity
H1D55_RS11885	COG0733	neurotransmitter:sodium symporter activity
H1D55_RS11895	COG0625	glutathione transferase activity
H1D55_RS11925	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H1D55_RS11930	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H1D55_RS11935	COG0596	Alpha beta hydrolase
H1D55_RS11960	COG0488	(ABC) transporter
H1D55_RS11965	COG0586	Pfam SNARE associated Golgi protein
H1D55_RS11975	COG0187	DNA topoisomerase II activity
H1D55_RS11985	COG0592	DNA-directed DNA polymerase activity
H1D55_RS12010	COG0706	membrane insertase activity
H1D55_RS12025	COG1230	cation diffusion facilitator family transporter
H1D55_RS12030	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1D55_RS12045	COG0402	S-adenosylhomocysteine deaminase activity
H1D55_RS12055	COG0754	glutathionylspermidine amidase activity
H1D55_RS12065	COG0861	Integral membrane protein TerC family
H1D55_RS12070	COG0671	phosphoesterase, PA-phosphatase related
H1D55_RS12080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H1D55_RS12095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H1D55_RS12100	COG2951	lytic endotransglycosylase activity
H1D55_RS12130	COG0583	DNA-binding transcription factor activity
H1D55_RS12150	COG0657	acetylesterase activity
H1D55_RS12155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H1D55_RS12195	COG1047	Peptidyl-prolyl cis-trans
H1D55_RS12205	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H1D55_RS12210	COG0196	riboflavin kinase activity
H1D55_RS12220	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1D55_RS12225	COG1309	transcriptional regulator
H1D55_RS12230	COG1116	anion transmembrane transporter activity
H1D55_RS12235	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H1D55_RS12240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H1D55_RS12245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1D55_RS12250	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H1D55_RS12270	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS12275	COG0546	phosphoglycolate phosphatase activity
H1D55_RS12330	COG3023	N-Acetylmuramoyl-L-alanine amidase
H1D55_RS12335	COG0728	peptidoglycan biosynthetic process
H1D55_RS12360	COG1596	polysaccharide export
H1D55_RS12365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H1D55_RS12375	COG1216	Glycosyl transferase, family 2
H1D55_RS12375	COG1442	glycosyl transferase family 8
H1D55_RS12380	COG0438	transferase activity, transferring glycosyl groups
H1D55_RS12390	COG0438	transferase activity, transferring glycosyl groups
H1D55_RS12400	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H1D55_RS12405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H1D55_RS12420	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H1D55_RS12430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1D55_RS12440	COG2186	Transcriptional regulator
H1D55_RS12450	COG0277	FAD linked oxidase domain protein
H1D55_RS12455	COG1448	Aminotransferase
H1D55_RS12460	COG1802	Transcriptional regulator
H1D55_RS12475	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H1D55_RS12560	COG0564	pseudouridine synthase activity
H1D55_RS12600	COG0251	oxidation-reduction process
H1D55_RS12605	COG1113	amino acid transport
H1D55_RS12610	COG1113	amino acid transport
H1D55_RS12630	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H1D55_RS12635	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS12640	COG1024	Enoyl-CoA hydratase
H1D55_RS12645	COG1024	Enoyl-CoA hydratase
H1D55_RS12650	COG0477	Major facilitator Superfamily
H1D55_RS12655	COG3916	Acyl-homoserine-lactone synthase
H1D55_RS12665	COG2197	response regulator
H1D55_RS12675	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS12680	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H1D55_RS12680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H1D55_RS12680	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H1D55_RS12680	COG3321	synthase
H1D55_RS12700	COG2267	carboxylic ester hydrolase activity
H1D55_RS12720	COG0271	Belongs to the BolA IbaG family
H1D55_RS12730	COG1192	Involved in chromosome partitioning
H1D55_RS12745	COG0586	Pfam SNARE associated Golgi protein
H1D55_RS12750	COG2259	Doxx family
H1D55_RS12755	COG4399	Belongs to the UPF0754 family
H1D55_RS12760	COG0519	Catalyzes the synthesis of GMP from XMP
H1D55_RS12760	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H1D55_RS12805	COG0281	malic enzyme
H1D55_RS12810	COG2837	iron assimilation
H1D55_RS12815	COG1280	lysine exporter protein (LysE YggA)
H1D55_RS12820	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H1D55_RS12825	COG1121	(ABC) transporter
H1D55_RS12890	COG0386	Belongs to the glutathione peroxidase family
H1D55_RS12905	COG1309	transcriptional regulator
H1D55_RS12910	COG0697	spore germination
H1D55_RS12920	COG0758	DNA mediated transformation
H1D55_RS12990	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H1D55_RS13000	COG0655	NAD(P)H dehydrogenase (quinone) activity
H1D55_RS13040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H1D55_RS13050	COG0477	Major facilitator Superfamily
H1D55_RS13060	COG1253	flavin adenine dinucleotide binding
H1D55_RS13070	COG2860	membrane
H1D55_RS13075	COG0477	Major facilitator Superfamily
H1D55_RS13085	COG0318	PFAM AMP-dependent synthetase and ligase
H1D55_RS13100	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H1D55_RS13115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1D55_RS13130	COG0606	chelatase, subunit chli
H1D55_RS13140	COG0347	Belongs to the P(II) protein family
H1D55_RS13145	COG0004	ammonium transporteR
H1D55_RS13155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1D55_RS13155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H1D55_RS13195	COG0795	lipopolysaccharide-transporting ATPase activity
H1D55_RS13200	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H1D55_RS13205	COG0793	Belongs to the peptidase S41A family
H1D55_RS13220	COG2197	response regulator
H1D55_RS13230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H1D55_RS13240	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H1D55_RS13245	COG4974	Belongs to the 'phage' integrase family
H1D55_RS13270	COG0772	Belongs to the SEDS family
H1D55_RS13275	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H1D55_RS13280	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H1D55_RS13285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H1D55_RS13310	COG0697	spore germination
H1D55_RS13315	COG1538	Outer membrane efflux protein
H1D55_RS13335	COG3275	phosphorelay sensor kinase activity
H1D55_RS13345	COG0181	hydroxymethylbilane synthase activity
H1D55_RS13390	COG1716	ATPase activity
H1D55_RS13395	COG0546	phosphoglycolate phosphatase activity
H1D55_RS13495	COG2056	Na+-H+ antiporter family
H1D55_RS13510	COG0326	Molecular chaperone. Has ATPase activity
H1D55_RS13525	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H1D55_RS13585	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H1D55_RS13590	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1D55_RS13590	COG2169	Transcriptional regulator
H1D55_RS13620	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H1D55_RS13630	COG0497	DNA recombination
H1D55_RS13645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H1D55_RS13655	COG0237	dephospho-CoA kinase activity
H1D55_RS13660	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
H1D55_RS13710	COG0195	Participates in both transcription termination and antitermination
H1D55_RS13725	COG1320	monovalent cation:proton antiporter activity
H1D55_RS13730	COG2212	antiporter activity
H1D55_RS13735	COG1863	multisubunit Na H antiporter MnhE subunit
H1D55_RS13740	COG0651	ATP synthesis coupled electron transport
H1D55_RS13745	COG1006	Multisubunit Na H antiporter MnhC subunit
H1D55_RS13750	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1D55_RS13750	COG2111	Na H antiporter
H1D55_RS13765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H1D55_RS13770	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1D55_RS13785	COG2226	methyltransferase
H1D55_RS13805	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H1D55_RS13810	COG1074	ATP-dependent DNA helicase activity
H1D55_RS13815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H1D55_RS13820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H1D55_RS13835	COG0598	Magnesium transport protein CorA
H1D55_RS13840	COG0789	Transcriptional regulator
H1D55_RS13845	COG0484	heat shock protein binding
H1D55_RS13860	COG0475	glutathione-regulated potassium exporter activity
H1D55_RS13860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1D55_RS13865	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H1D55_RS13885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1D55_RS13895	COG4535	Mg2 and Co2 transporter CorC
H1D55_RS13900	COG0425	Belongs to the sulfur carrier protein TusA family
H1D55_RS13905	COG0644	oxidoreductase
H1D55_RS13905	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H1D55_RS13915	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H1D55_RS13930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H1D55_RS13935	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H1D55_RS13945	COG0493	'glutamate synthase
H1D55_RS13945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1D55_RS13970	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H1D55_RS13985	COG0534	Mate efflux family protein
H1D55_RS13995	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H1D55_RS14000	COG4221	oxidoreductase activity
H1D55_RS14005	COG0583	DNA-binding transcription factor activity
H1D55_RS14020	COG0318	PFAM AMP-dependent synthetase and ligase
H1D55_RS14025	COG1530	ribonuclease E activity
H1D55_RS14035	COG0546	phosphoglycolate phosphatase activity
H1D55_RS14040	COG2378	regulation of single-species biofilm formation
H1D55_RS14045	COG0625	glutathione transferase activity
H1D55_RS14055	COG0583	DNA-binding transcription factor activity
H1D55_RS14120	COG0473	3-isopropylmalate dehydrogenase activity
H1D55_RS14175	COG1301	dicarboxylic acid transport
H1D55_RS14185	COG1560	Kdo2-lipid A biosynthetic process
H1D55_RS14190	COG1280	lysine exporter protein (LysE YggA)
H1D55_RS14195	COG0488	(ABC) transporter
H1D55_RS14200	COG2900	Belongs to the SlyX family
H1D55_RS14210	COG1733	regulation of RNA biosynthetic process
H1D55_RS14235	COG0210	DNA helicase
H1D55_RS14240	COG0724	RNA recognition motif
H1D55_RS14260	COG4651	solute:proton antiporter activity
H1D55_RS14260	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H1D55_RS14285	COG0788	formyltetrahydrofolate deformylase activity
H1D55_RS14385	COG2813	Specifically methylates the guanine in position
H1D55_RS14385	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1D55_RS14395	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H1D55_RS14405	COG4774	siderophore transport
H1D55_RS14415	COG0740	serine-type endopeptidase activity
H1D55_RS14435	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H1D55_RS14435	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H1D55_RS14440	COG0857	belongs to the CobB CobQ family
H1D55_RS14440	COG0280	phosphate acetyltransferase
H1D55_RS14445	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H1D55_RS14455	COG0800	Aldolase
H1D55_RS14465	COG3265	gluconokinase activity
H1D55_RS14470	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS14480	COG2267	carboxylic ester hydrolase activity
H1D55_RS14495	COG0793	Belongs to the peptidase S41A family
H1D55_RS14530	COG1426	Protein conserved in bacteria
H1D55_RS14570	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H1D55_RS14580	COG1162	GTPase activity
H1D55_RS14585	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H1D55_RS14600	COG1538	Outer membrane efflux protein
H1D55_RS14605	COG0577	efflux transmembrane transporter activity
H1D55_RS14605	COG1136	(ABC) transporter
H1D55_RS14610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H1D55_RS14635	COG0028	Belongs to the TPP enzyme family
H1D55_RS14640	COG0440	acetolactate synthase activity
H1D55_RS14670	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H1D55_RS14685	COG0084	hydrolase, TatD family'
H1D55_RS14700	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H1D55_RS14710	COG0583	DNA-binding transcription factor activity
H1D55_RS14720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1D55_RS14725	COG2814	Major facilitator Superfamily
H1D55_RS14735	COG0697	spore germination
H1D55_RS14765	COG3622	Belongs to the hyi family
H1D55_RS14770	COG2084	Dehydrogenase
H1D55_RS14775	COG1024	Enoyl-CoA hydratase
H1D55_RS14780	COG0784	Response regulator, receiver
H1D55_RS14780	COG5002	protein histidine kinase activity
H1D55_RS14780	COG2205	protein histidine kinase activity
H1D55_RS14800	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H1D55_RS14810	COG3956	TIGRFAM MazG family protein
H1D55_RS14815	COG1555	photosystem II stabilization
H1D55_RS14820	COG0617	tRNA 3'-terminal CCA addition
H1D55_RS14825	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H1D55_RS14845	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H1D55_RS14850	COG3028	Belongs to the UPF0307 family
H1D55_RS14855	COG0318	PFAM AMP-dependent synthetase and ligase
H1D55_RS14870	COG0625	glutathione transferase activity
H1D55_RS14875	COG1238	metal cluster binding
H1D55_RS14920	COG0072	phenylalanine-tRNA ligase activity
H1D55_RS14950	COG0248	Ppx GppA phosphatase
H1D55_RS14960	COG0037	tRNA processing
H1D55_RS14975	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1D55_RS14975	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1D55_RS15000	COG1764	response to oxidative stress
H1D55_RS15005	COG1846	Transcriptional regulator
H1D55_RS15015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1D55_RS15075	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H1D55_RS15080	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H1D55_RS15085	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H1D55_RS15095	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H1D55_RS15145	COG1214	PFAM Peptidase M22, glycoprotease
H1D55_RS15160	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
H1D55_RS15170	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H1D55_RS15175	COG0561	phosphatase activity
H1D55_RS15185	COG2132	Multicopper oxidase
H1D55_RS15205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H1D55_RS15210	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H1D55_RS15215	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H1D55_RS15245	COG1063	alcohol dehydrogenase
H1D55_RS15250	COG0583	DNA-binding transcription factor activity
H1D55_RS15255	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS15260	COG2814	Major facilitator Superfamily
H1D55_RS15265	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H1D55_RS15270	COG1309	transcriptional regulator
H1D55_RS15285	COG1053	succinate dehydrogenase
H1D55_RS15290	COG0583	DNA-binding transcription factor activity
H1D55_RS15305	COG0583	DNA-binding transcription factor activity
H1D55_RS15315	COG0583	DNA-binding transcription factor activity
H1D55_RS15330	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H1D55_RS15385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1D55_RS15405	COG0745	RESPONSE REGULATOR receiver
H1D55_RS15445	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H1D55_RS15475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H1D55_RS15480	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H1D55_RS15500	COG0583	DNA-binding transcription factor activity
H1D55_RS15520	COG0668	transmembrane transport
H1D55_RS15530	COG2081	HI0933 family
H1D55_RS15535	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H1D55_RS15565	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1D55_RS15565	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H1D55_RS15575	COG0489	protein tyrosine kinase activity
H1D55_RS15580	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H1D55_RS15625	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H1D55_RS15635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H1D55_RS15650	COG0730	response to heat
H1D55_RS15660	COG1196	nuclear chromosome segregation
H1D55_RS15680	COG2223	nitrite transmembrane transporter activity
H1D55_RS15685	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H1D55_RS15690	COG1877	trehalose-phosphatase activity
H1D55_RS15695	COG0596	Alpha beta hydrolase
H1D55_RS15695	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H1D55_RS15695	COG2226	methyltransferase
H1D55_RS15710	COG4106	trans-aconitate 2-methyltransferase activity
H1D55_RS15725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H1D55_RS15730	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H1D55_RS15735	COG0009	L-threonylcarbamoyladenylate synthase
H1D55_RS15740	COG3101	peptidyl-lysine hydroxylation
H1D55_RS15745	COG1399	metal-binding, possibly nucleic acid-binding protein
H1D55_RS15770	COG1652	LysM domain
H1D55_RS15775	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H1D55_RS15775	COG0352	thiamine-phosphate diphosphorylase activity
H1D55_RS15775	COG0351	phosphomethylpyrimidine kinase
H1D55_RS15785	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H1D55_RS15815	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H1D55_RS15845	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H1D55_RS15860	COG0358	DNA primase activity
H1D55_RS15870	COG0564	pseudouridine synthase activity
H1D55_RS15895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H1D55_RS15915	COG0583	DNA-binding transcription factor activity
H1D55_RS15920	COG0473	3-isopropylmalate dehydrogenase activity
H1D55_RS15930	COG0657	acetylesterase activity
H1D55_RS15940	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS15960	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H1D55_RS15960	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H1D55_RS15975	COG1981	membrane
H1D55_RS16020	COG0456	acetyltransferase
H1D55_RS16030	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H1D55_RS16035	COG0492	ferredoxin-NADP+ reductase activity
H1D55_RS16040	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H1D55_RS16040	COG1674	ftsk spoiiie
H1D55_RS16045	COG1280	lysine exporter protein (LysE YggA)
H1D55_RS16060	COG2894	cell division
H1D55_RS16075	COG0204	Acyl-transferase
H1D55_RS16080	COG2885	chlorophyll binding
H1D55_RS16085	COG0210	DNA helicase
H1D55_RS16095	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H1D55_RS16110	COG0121	glutamine amidotransferase
H1D55_RS16130	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H1D55_RS16135	COG0735	belongs to the Fur family
H1D55_RS16160	COG0420	3'-5' exonuclease activity
H1D55_RS16180	COG1090	epimerase
H1D55_RS16195	COG2050	protein possibly involved in aromatic compounds catabolism
H1D55_RS16205	COG2814	Major facilitator Superfamily
H1D55_RS16210	COG0405	Gamma-glutamyltransferase
H1D55_RS16220	COG0582	viral genome integration into host DNA
H1D55_RS16280	COG3646	Phage regulatory protein
H1D55_RS16435	COG4695	Portal protein
H1D55_RS16540	COG0477	Major facilitator Superfamily
H1D55_RS16545	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H1D55_RS16590	COG0531	amino acid
H1D55_RS16595	COG2040	homocysteine
H1D55_RS16620	COG1309	transcriptional regulator
H1D55_RS16625	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1D55_RS16630	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H1D55_RS16640	COG1607	acyl-coa hydrolase
H1D55_RS16650	COG0523	cobalamin synthesis protein
H1D55_RS16660	COG4681	YaeQ
H1D55_RS16670	COG1649	PFAM Uncharacterised BCR, COG1649
H1D55_RS16670	COG0726	polysaccharide deacetylase
H1D55_RS16675	COG1215	transferase activity, transferring glycosyl groups
H1D55_RS16685	COG1024	Enoyl-CoA hydratase
H1D55_RS16700	COG1414	Transcriptional regulator
H1D55_RS16720	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS16735	COG2271	Major facilitator Superfamily
H1D55_RS16745	COG2267	carboxylic ester hydrolase activity
H1D55_RS16750	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS16765	COG0028	Belongs to the TPP enzyme family
H1D55_RS16775	COG0477	Major facilitator Superfamily
H1D55_RS16780	COG0242	peptide deformylase activity
H1D55_RS16785	COG2066	Belongs to the glutaminase family
H1D55_RS16790	COG2207	Transcriptional regulator
H1D55_RS16795	COG2223	nitrite transmembrane transporter activity
H1D55_RS16810	COG0583	DNA-binding transcription factor activity
H1D55_RS16815	COG1028	Short-chain dehydrogenase reductase Sdr
H1D55_RS16820	COG2271	Major facilitator Superfamily
H1D55_RS16825	COG3959	Transketolase, thiamine diphosphate binding domain
H1D55_RS16830	COG3958	Transketolase
H1D55_RS16840	COG0306	phosphate transporter
H1D55_RS16860	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H1D55_RS16905	COG4181	ATPase activity
H1D55_RS16910	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H1D55_RS16940	COG0583	DNA-binding transcription factor activity
H1D55_RS16950	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H1D55_RS16955	COG1773	rubredoxin
H1D55_RS17005	COG2851	Citrate transporter
H1D55_RS17010	COG1253	flavin adenine dinucleotide binding
H1D55_RS17050	COG0804	urea catabolic process
H1D55_RS17060	COG0830	nickel cation binding
H1D55_RS17075	COG0742	ribosomal rna small subunit methyltransferase
H1D55_RS17080	COG0768	penicillin binding
H1D55_RS17105	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H1D55_RS17110	COG2878	Part of a membrane complex involved in electron transport
H1D55_RS17115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H1D55_RS17125	COG3384	dioxygenase
H1D55_RS17150	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H1D55_RS17470	COG0739	heme binding
H1D55_RS17520	COG2194	sulfuric ester hydrolase activity
H1D55_RS17555	COG0006	proline dipeptidase activity
H1D55_RS17560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1D55_RS17565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H1D55_RS17585	COG1279	arginine transmembrane transporter activity
H1D55_RS17590	COG0583	DNA-binding transcription factor activity
H1D55_RS17630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1D55_RS17635	COG1388	LysM domain
H1D55_RS17635	COG0741	lytic transglycosylase activity
H1D55_RS17635	COG1388	LysM domain
H1D55_RS17635	COG0741	lytic transglycosylase activity
H1D55_RS17645	COG4174	ABC transporter (Permease)
H1D55_RS17650	COG4239	(ABC) transporter, permease
H1D55_RS17655	COG4172	Belongs to the ABC transporter superfamily
H1D55_RS17675	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1D55_RS17685	COG3706	GGDEF domain
H1D55_RS17685	COG5001	Diguanylate cyclase
H1D55_RS17685	COG4251	negative regulation of phosphorylation
H1D55_RS17685	COG2203	Gaf domain
H1D55_RS17695	COG0446	pyridine nucleotide-disulphide oxidoreductase
H1D55_RS17695	COG1902	pentaerythritol trinitrate reductase activity
H1D55_RS17710	COG4269	membrane
H1D55_RS17750	COG1113	amino acid transport
H1D55_RS17760	COG0531	amino acid
H1D55_RS17780	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS17800	COG1113	amino acid transport
H1D55_RS17835	COG0697	spore germination
H1D55_RS17840	COG2721	sulfolactate sulfo-lyase activity
H1D55_RS17845	COG2271	Major facilitator Superfamily
H1D55_RS17850	COG4948	Mandelate Racemase Muconate Lactonizing
H1D55_RS17860	COG1012	belongs to the aldehyde dehydrogenase family
H1D55_RS17865	COG2186	Transcriptional regulator
H1D55_RS17890	COG1960	acyl-CoA dehydrogenase activity
H1D55_RS17995	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H1D55_RS18015	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H1D55_RS18195	COG0358	DNA primase activity
H1D55_RS18255	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H1D55_RS18290	COG0587	DNA-directed DNA polymerase activity
H1D55_RS18310	COG0587	DNA-directed DNA polymerase activity
H1D55_RS18325	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1D55_RS18325	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H1D55_RS18375	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1D55_RS18375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H1D55_RS18380	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H1D55_RS18455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H1D55_RS18550	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H1D55_RS18560	COG2026	Addiction module toxin, RelE StbE family
H1D55_RS18565	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
H1D55_RS18620	COG1660	Displays ATPase and GTPase activities
H1D55_RS18695	COG1192	Involved in chromosome partitioning
H1D55_RS18745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H1D55_RS18765	COG3451	type IV secretory pathway VirB4