locus-tag	class	description
DYB08_RS00015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DYB08_RS00020	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DYB08_RS00070	COG0339	signal peptide processing
DYB08_RS00080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DYB08_RS00115	COG0702	epimerase
DYB08_RS00120	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DYB08_RS00140	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DYB08_RS00170	COG0316	Belongs to the HesB IscA family
DYB08_RS00175	COG0822	iron-sulfur transferase activity
DYB08_RS00200	COG0776	regulation of translation
DYB08_RS00205	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DYB08_RS00210	COG2207	Transcriptional regulator
DYB08_RS00215	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYB08_RS00220	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS00230	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS00250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DYB08_RS00270	COG4264	IucA IucC family
DYB08_RS00275	COG4264	IucA IucC family
DYB08_RS00335	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DYB08_RS00355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DYB08_RS00360	COG0730	response to heat
DYB08_RS00395	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYB08_RS00410	COG1131	(ABC) transporter
DYB08_RS00415	COG0842	Transport permease protein
DYB08_RS00420	COG0842	Transport permease protein
DYB08_RS00475	COG2226	methyltransferase
DYB08_RS00500	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DYB08_RS00535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DYB08_RS00545	COG0133	tryptophan synthase activity
DYB08_RS00560	COG3706	GGDEF domain
DYB08_RS00575	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DYB08_RS00580	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
DYB08_RS00585	COG0022	dehydrogenase e1 component
DYB08_RS00590	COG0508	dehydrogenase complex catalyzes the overall conversion of
DYB08_RS00595	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYB08_RS00605	COG1063	alcohol dehydrogenase
DYB08_RS00610	COG3781	membrane
DYB08_RS00620	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYB08_RS00620	COG3453	Protein conserved in bacteria
DYB08_RS00630	COG0730	response to heat
DYB08_RS00645	COG3708	Transcriptional regulator
DYB08_RS00645	COG2207	Transcriptional regulator
DYB08_RS00650	COG1733	regulation of RNA biosynthetic process
DYB08_RS00655	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DYB08_RS00665	COG2188	Transcriptional regulator
DYB08_RS00680	COG4521	taurine ABC transporter
DYB08_RS00685	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYB08_RS00705	COG0477	Major facilitator Superfamily
DYB08_RS00715	COG1027	Aspartate ammonia-lyase
DYB08_RS00730	COG0583	DNA-binding transcription factor activity
DYB08_RS00735	COG0583	DNA-binding transcription factor activity
DYB08_RS00740	COG0183	Belongs to the thiolase family
DYB08_RS00745	COG2031	fatty acid transporter
DYB08_RS00750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DYB08_RS00760	COG0583	DNA-binding transcription factor activity
DYB08_RS00780	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS00790	COG2207	Transcriptional regulator
DYB08_RS00805	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS00830	COG0543	2 iron, 2 sulfur cluster binding
DYB08_RS00830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DYB08_RS00835	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DYB08_RS00840	COG4638	Rieske (2fe-2S)
DYB08_RS00850	COG0725	ABC transporter, periplasmic molybdate-binding protein
DYB08_RS00855	COG4149	molybdate abc transporter
DYB08_RS00860	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DYB08_RS00865	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS00870	COG1535	isochorismatase
DYB08_RS00870	COG3433	isochorismatase activity
DYB08_RS00935	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYB08_RS00950	COG0753	catalase activity
DYB08_RS00960	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DYB08_RS00990	COG3539	Fimbrial protein
DYB08_RS01010	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYB08_RS01035	COG2072	flavoprotein involved in K transport
DYB08_RS01045	COG1538	Outer membrane efflux protein
DYB08_RS01050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DYB08_RS01055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYB08_RS01075	COG0745	RESPONSE REGULATOR receiver
DYB08_RS01080	COG2205	protein histidine kinase activity
DYB08_RS01090	COG2207	Transcriptional regulator
DYB08_RS01105	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS01160	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DYB08_RS01280	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYB08_RS01300	COG1120	ATPase activity
DYB08_RS01305	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYB08_RS01315	COG1064	alcohol dehydrogenase
DYB08_RS01330	COG2207	Transcriptional regulator
DYB08_RS01335	COG2084	Dehydrogenase
DYB08_RS01350	COG2186	Transcriptional regulator
DYB08_RS01360	COG0583	DNA-binding transcription factor activity
DYB08_RS01365	COG4948	Mandelate Racemase Muconate Lactonizing
DYB08_RS01370	COG4829	muconolactone delta-isomerase
DYB08_RS01380	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DYB08_RS01385	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DYB08_RS01390	COG0183	Belongs to the thiolase family
DYB08_RS01395	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DYB08_RS01405	COG1012	belongs to the aldehyde dehydrogenase family
DYB08_RS01415	COG3733	amine oxidase
DYB08_RS01425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DYB08_RS01435	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS01445	COG4638	Rieske (2fe-2S)
DYB08_RS01465	COG0154	amidase activity
DYB08_RS01475	COG2814	Major facilitator Superfamily
DYB08_RS01500	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS01520	COG1414	Transcriptional regulator
DYB08_RS01535	COG2391	methyltransferase activity
DYB08_RS01545	COG4993	Dehydrogenase
DYB08_RS01550	COG3659	wide pore channel activity
DYB08_RS01555	COG3420	alginic acid biosynthetic process
DYB08_RS01560	COG0710	3-dehydroquinate dehydratase activity
DYB08_RS01565	COG3485	protocatechuate 3,4-dioxygenase
DYB08_RS01570	COG3485	protocatechuate 3,4-dioxygenase
DYB08_RS01575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DYB08_RS01580	COG2271	Major facilitator Superfamily
DYB08_RS01585	COG0596	Alpha beta hydrolase
DYB08_RS01590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DYB08_RS01595	COG0183	Belongs to the thiolase family
DYB08_RS01600	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DYB08_RS01605	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DYB08_RS01615	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DYB08_RS01620	COG2323	membrane
DYB08_RS01665	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYB08_RS01665	COG1902	pentaerythritol trinitrate reductase activity
DYB08_RS01690	COG0542	response to heat
DYB08_RS01695	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DYB08_RS01725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DYB08_RS01730	COG0569	domain protein
DYB08_RS01735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
DYB08_RS01750	COG4774	siderophore transport
DYB08_RS01755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DYB08_RS01765	COG1585	Membrane protein implicated in regulation of membrane protease activity
DYB08_RS01785	COG1294	oxidase, subunit
DYB08_RS01790	COG4890	Cyd operon protein YbgT
DYB08_RS01805	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
DYB08_RS01815	COG0552	protein localization to endoplasmic reticulum
DYB08_RS01840	COG0517	IMP dehydrogenase activity
DYB08_RS01840	COG0516	GMP reductase activity
DYB08_RS01845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DYB08_RS01850	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DYB08_RS01860	COG0583	DNA-binding transcription factor activity
DYB08_RS01865	COG0024	Methionine aminopeptidase
DYB08_RS01895	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYB08_RS01895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DYB08_RS01900	COG1105	Belongs to the carbohydrate kinase PfkB family
DYB08_RS01905	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYB08_RS01905	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
DYB08_RS01905	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DYB08_RS01925	COG3300	MHYT domain
DYB08_RS01925	COG5001	Diguanylate cyclase
DYB08_RS01940	COG2135	peptidase activity
DYB08_RS01945	COG0659	secondary active sulfate transmembrane transporter activity
DYB08_RS01960	COG1113	amino acid transport
DYB08_RS01970	COG1522	sequence-specific DNA binding
DYB08_RS01995	COG1011	Hydrolase
DYB08_RS02000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DYB08_RS02010	COG2137	regulation of response to DNA damage stimulus
DYB08_RS02025	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYB08_RS02060	COG0575	Belongs to the CDS family
DYB08_RS02065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DYB08_RS02090	COG3852	Histidine kinase
DYB08_RS02095	COG2204	response regulator
DYB08_RS02155	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DYB08_RS02160	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DYB08_RS02180	COG0697	spore germination
DYB08_RS02185	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYB08_RS02195	COG0303	'Molybdopterin
DYB08_RS02200	COG0315	cyclic pyranopterin monophosphate synthase activity
DYB08_RS02200	COG0521	Mo-molybdopterin cofactor biosynthetic process
DYB08_RS02215	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DYB08_RS02220	COG0243	molybdopterin cofactor binding
DYB08_RS02230	COG0243	molybdopterin cofactor binding
DYB08_RS02235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYB08_RS02240	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYB08_RS02240	COG2146	nitrite reductase [NAD(P)H] activity
DYB08_RS02250	COG0745	RESPONSE REGULATOR receiver
DYB08_RS02255	COG1116	anion transmembrane transporter activity
DYB08_RS02255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYB08_RS02275	COG0511	ligase activity, forming carbon-carbon bonds
DYB08_RS02290	COG2814	Major facilitator Superfamily
DYB08_RS02630	COG0069	glutamate synthase activity
DYB08_RS02650	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DYB08_RS02660	COG1454	alcohol dehydrogenase
DYB08_RS02665	COG0824	Thioesterase
DYB08_RS02675	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DYB08_RS02690	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DYB08_RS02695	COG2030	dehydratase
DYB08_RS02705	COG0183	Belongs to the thiolase family
DYB08_RS02715	COG0583	DNA-binding transcription factor activity
DYB08_RS02720	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DYB08_RS02730	COG1522	sequence-specific DNA binding
DYB08_RS02735	COG3135	benzoate transporter
DYB08_RS02745	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DYB08_RS02785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYB08_RS02840	COG0589	response to stress
DYB08_RS02845	COG0659	secondary active sulfate transmembrane transporter activity
DYB08_RS02925	COG0589	response to stress
DYB08_RS02930	COG0488	(ABC) transporter
DYB08_RS02950	COG4773	Receptor
DYB08_RS02980	COG0668	transmembrane transport
DYB08_RS02990	COG1309	transcriptional regulator
DYB08_RS03010	COG1605	Chorismate mutase
DYB08_RS03020	COG4221	oxidoreductase activity
DYB08_RS03030	COG0308	aminopeptidase N
DYB08_RS03050	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
DYB08_RS03060	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DYB08_RS03065	COG1454	alcohol dehydrogenase
DYB08_RS03085	COG0531	amino acid
DYB08_RS03090	COG4303	Ethanolamine ammonia lyase large subunit
DYB08_RS03095	COG4302	ethanolamine ammonia-lyase activity
DYB08_RS03100	COG0519	Catalyzes the synthesis of GMP from XMP
DYB08_RS03100	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DYB08_RS03105	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYB08_RS03115	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DYB08_RS03130	COG0697	spore germination
DYB08_RS03135	COG1923	regulation of RNA biosynthetic process
DYB08_RS03145	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
DYB08_RS03150	COG0802	atpase or kinase
DYB08_RS03170	COG1187	pseudouridine synthase activity
DYB08_RS03185	COG0583	DNA-binding transcription factor activity
DYB08_RS03200	COG2814	Major facilitator Superfamily
DYB08_RS03205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYB08_RS03235	COG0729	surface antigen
DYB08_RS03260	COG0174	glutamine synthetase
DYB08_RS03265	COG0745	RESPONSE REGULATOR receiver
DYB08_RS03270	COG2205	protein histidine kinase activity
DYB08_RS03280	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DYB08_RS03285	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DYB08_RS03310	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DYB08_RS03315	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYB08_RS03320	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS03335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYB08_RS03340	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYB08_RS03360	COG0583	DNA-binding transcription factor activity
DYB08_RS03380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYB08_RS03390	COG3658	cytochrome
DYB08_RS03395	COG1215	transferase activity, transferring glycosyl groups
DYB08_RS03400	COG1649	PFAM Uncharacterised BCR, COG1649
DYB08_RS03400	COG0726	polysaccharide deacetylase
DYB08_RS03425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DYB08_RS03430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DYB08_RS03440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
DYB08_RS03465	COG0305	Participates in initiation and elongation during chromosome replication
DYB08_RS03470	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DYB08_RS03480	COG1305	Transglutaminase-like
DYB08_RS03490	COG2308	Evidence 4 Homologs of previously reported genes of
DYB08_RS03520	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
DYB08_RS03525	COG0138	bifunctional purine biosynthesis protein purh
DYB08_RS03530	COG0151	Belongs to the GarS family
DYB08_RS03535	COG1464	Belongs to the NlpA lipoprotein family
DYB08_RS03540	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYB08_RS03545	COG2011	ABC-type metal ion transport system permease component
DYB08_RS03550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYB08_RS03560	COG1301	dicarboxylic acid transport
DYB08_RS03590	COG1794	racemase activity, acting on amino acids and derivatives
DYB08_RS03600	COG3008	intermembrane lipid transfer
DYB08_RS03600	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DYB08_RS03605	COG2995	paraquat-inducible protein a
DYB08_RS03615	COG2985	domain, Protein
DYB08_RS03645	COG0477	Major facilitator Superfamily
DYB08_RS03700	COG2186	Transcriptional regulator
DYB08_RS03710	COG0786	glutamate:sodium symporter activity
DYB08_RS03715	COG3243	poly(R)-hydroxyalkanoic acid synthase
DYB08_RS03745	COG3111	PFAM Bacterial OB fold (BOF) protein
DYB08_RS03845	COG1610	YqeY-like protein
DYB08_RS03850	COG4783	chaperone-mediated protein folding
DYB08_RS03875	COG1286	toxin biosynthetic process
DYB08_RS03905	COG0778	Nitroreductase
DYB08_RS03915	COG0513	Belongs to the DEAD box helicase family
DYB08_RS03935	COG2363	Small membrane protein
DYB08_RS03965	COG1234	tRNA 3'-trailer cleavage
DYB08_RS03970	COG2195	Cleaves the N-terminal amino acid of tripeptides
DYB08_RS03980	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DYB08_RS03990	COG2819	hydrolase of the alpha beta superfamily
DYB08_RS03995	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS04000	COG1301	dicarboxylic acid transport
DYB08_RS04010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DYB08_RS04015	COG3139	Protein of unknown function (DUF1315)
DYB08_RS04020	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DYB08_RS04025	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DYB08_RS04035	COG0494	nUDIX hydrolase
DYB08_RS04045	COG0642	Histidine kinase
DYB08_RS04065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
DYB08_RS04075	COG1720	tRNA m6t6A37 methyltransferase activity
DYB08_RS04090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYB08_RS04095	COG0826	peptidase U32
DYB08_RS04100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYB08_RS04110	COG4598	ABC transporter
DYB08_RS04115	COG4160	amino acid transport
DYB08_RS04120	COG4215	(ABC) transporter
DYB08_RS04145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYB08_RS04200	COG1131	(ABC) transporter
DYB08_RS04205	COG0842	Transport permease protein
DYB08_RS04220	COG0772	Belongs to the SEDS family
DYB08_RS04225	COG2951	lytic endotransglycosylase activity
DYB08_RS04250	COG2207	Transcriptional regulator
DYB08_RS04265	COG0052	Belongs to the universal ribosomal protein uS2 family
DYB08_RS04270	COG0024	Methionine aminopeptidase
DYB08_RS04280	COG2223	nitrite transmembrane transporter activity
DYB08_RS04290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYB08_RS04295	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DYB08_RS04300	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS04315	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DYB08_RS04320	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DYB08_RS04325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DYB08_RS04345	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYB08_RS04350	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DYB08_RS04355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DYB08_RS04390	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DYB08_RS04400	COG0174	glutamine synthetase
DYB08_RS04415	COG0512	Glutamine amidotransferase of anthranilate synthase
DYB08_RS04420	COG0308	aminopeptidase N
DYB08_RS04455	COG1529	Aldehyde oxidase and xanthine dehydrogenase
DYB08_RS04465	COG0302	gtp cyclohydrolase
DYB08_RS04490	COG3739	integral membrane protein
DYB08_RS04505	COG1169	isochorismate synthase
DYB08_RS04515	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
DYB08_RS04520	COG1132	(ABC) transporter
DYB08_RS04525	COG1132	(ABC) transporter
DYB08_RS04540	COG1535	isochorismatase
DYB08_RS04540	COG3433	isochorismatase activity
DYB08_RS04545	COG1021	2,3-dihydroxybenzoate-AMP ligase
DYB08_RS04550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYB08_RS04560	COG4774	siderophore transport
DYB08_RS04565	COG4607	ABC-type enterochelin transport system periplasmic component
DYB08_RS04570	COG4604	ABC transporter, ATP-binding protein
DYB08_RS04575	COG4605	iron ion homeostasis
DYB08_RS04580	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DYB08_RS04585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYB08_RS04600	COG2964	Protein conserved in bacteria
DYB08_RS04610	COG1741	Belongs to the pirin family
DYB08_RS04630	COG1309	transcriptional regulator
DYB08_RS04640	COG4948	Mandelate Racemase Muconate Lactonizing
DYB08_RS04645	COG2814	Major facilitator Superfamily
DYB08_RS04680	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DYB08_RS04680	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYB08_RS04685	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYB08_RS04690	COG1012	belongs to the aldehyde dehydrogenase family
DYB08_RS04700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DYB08_RS04705	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DYB08_RS04715	COG0583	DNA-binding transcription factor activity
DYB08_RS04720	COG1113	amino acid transport
DYB08_RS04740	COG2508	Transcriptional regulator
DYB08_RS04740	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
DYB08_RS04780	COG2879	small protein
DYB08_RS04785	COG1966	Carbon starvation protein
DYB08_RS04830	COG1067	ATP-dependent peptidase activity
DYB08_RS04835	COG0583	DNA-binding transcription factor activity
DYB08_RS04860	COG1686	Belongs to the peptidase S11 family
DYB08_RS04865	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DYB08_RS04900	COG0616	signal peptide processing
DYB08_RS04905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DYB08_RS04915	COG0573	inorganic phosphate transmembrane transporter activity
DYB08_RS04920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DYB08_RS04925	COG1113	amino acid transport
DYB08_RS04930	COG3961	Belongs to the TPP enzyme family
DYB08_RS04935	COG1522	sequence-specific DNA binding
DYB08_RS04945	COG0076	glutamate decarboxylase activity
DYB08_RS04950	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DYB08_RS04960	COG1309	transcriptional regulator
DYB08_RS04975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DYB08_RS05010	COG0352	thiamine-phosphate diphosphorylase activity
DYB08_RS05035	COG0612	Peptidase, M16
DYB08_RS05045	COG1823	symporter activity
DYB08_RS05050	COG0583	DNA-binding transcription factor activity
DYB08_RS05055	COG0477	Major facilitator Superfamily
DYB08_RS05080	COG1187	pseudouridine synthase activity
DYB08_RS05095	COG1686	Belongs to the peptidase S11 family
DYB08_RS05100	COG1252	NADH dehydrogenase
DYB08_RS05110	COG0415	Belongs to the DNA photolyase family
DYB08_RS05125	COG1215	transferase activity, transferring glycosyl groups
DYB08_RS05155	COG2070	2-Nitropropane dioxygenase
DYB08_RS05210	COG0556	nucleotide-excision repair
DYB08_RS05230	COG0436	Aminotransferase
DYB08_RS05260	COG4221	oxidoreductase activity
DYB08_RS05270	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DYB08_RS05275	COG1381	Involved in DNA repair and RecF pathway recombination
DYB08_RS05285	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DYB08_RS05300	COG0681	Belongs to the peptidase S26 family
DYB08_RS05315	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DYB08_RS05335	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DYB08_RS05340	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DYB08_RS05345	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DYB08_RS05355	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
DYB08_RS05360	COG4208	sulfate ABC transporter
DYB08_RS05365	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DYB08_RS05370	COG0583	DNA-binding transcription factor activity
DYB08_RS05375	COG4625	pathogenesis
DYB08_RS05390	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DYB08_RS05405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DYB08_RS05415	COG1056	cytidyltransferase-related domain
DYB08_RS05415	COG1051	belongs to the nudix hydrolase family
DYB08_RS05420	COG1024	Enoyl-CoA hydratase
DYB08_RS05430	COG2814	Major facilitator Superfamily
DYB08_RS05435	COG0047	phosphoribosylformylglycinamidine synthase activity
DYB08_RS05435	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DYB08_RS05460	COG1473	amidohydrolase
DYB08_RS05465	COG0824	Thioesterase
DYB08_RS05485	COG0823	Involved in the tonB-independent uptake of proteins
DYB08_RS05505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYB08_RS05540	COG0628	permease
DYB08_RS05550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DYB08_RS05555	COG0596	Alpha beta hydrolase
DYB08_RS05560	COG0616	signal peptide processing
DYB08_RS05560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DYB08_RS05585	COG1136	(ABC) transporter
DYB08_RS05590	COG4591	ABC-type transport system involved in lipoprotein release permease component
DYB08_RS05625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYB08_RS05645	COG0463	Glycosyl transferase, family 2
DYB08_RS05675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DYB08_RS05680	COG1280	lysine exporter protein (LysE YggA)
DYB08_RS05690	COG0019	diaminopimelate decarboxylase activity
DYB08_RS05700	COG1113	amino acid transport
DYB08_RS05715	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
DYB08_RS05725	COG3339	Conserved Protein
DYB08_RS05730	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DYB08_RS05735	COG0243	molybdopterin cofactor binding
DYB08_RS05740	COG1929	Belongs to the glycerate kinase type-1 family
DYB08_RS05755	COG0778	Nitroreductase
DYB08_RS05780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYB08_RS05795	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DYB08_RS05825	COG0741	lytic transglycosylase activity
DYB08_RS05845	COG0584	glycerophosphoryl diester phosphodiesterase
DYB08_RS05850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYB08_RS05875	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DYB08_RS05880	COG1597	lipid kinase activity
DYB08_RS05895	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DYB08_RS05900	COG0477	Major facilitator Superfamily
DYB08_RS05955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DYB08_RS05980	COG0505	Belongs to the CarA family
DYB08_RS06000	COG0589	response to stress
DYB08_RS06015	COG2843	Capsule synthesis protein
DYB08_RS06055	COG2321	neutral zinc metallopeptidase
DYB08_RS06060	COG2354	Protein conserved in bacteria
DYB08_RS06080	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DYB08_RS06105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DYB08_RS06110	COG1053	succinate dehydrogenase
DYB08_RS06115	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
DYB08_RS06120	COG2009	succinate dehydrogenase
DYB08_RS06160	COG2921	Belongs to the UPF0250 family
DYB08_RS06165	COG0321	lipoyl(octanoyl) transferase activity
DYB08_RS06180	COG0531	amino acid
DYB08_RS06190	COG1733	regulation of RNA biosynthetic process
DYB08_RS06195	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DYB08_RS06200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DYB08_RS06200	COG1648	precorrin-2 dehydrogenase activity
DYB08_RS06215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DYB08_RS06245	COG0671	phosphoesterase, PA-phosphatase related
DYB08_RS06250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYB08_RS06260	COG1538	Outer membrane efflux protein
DYB08_RS06265	COG0393	Putative heavy-metal-binding
DYB08_RS06270	COG0393	Putative heavy-metal-binding
DYB08_RS06280	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS06290	COG0525	valine-tRNA ligase activity
DYB08_RS06310	COG0583	DNA-binding transcription factor activity
DYB08_RS06320	COG0004	ammonium transporteR
DYB08_RS06330	COG0642	Histidine kinase
DYB08_RS06335	COG0745	RESPONSE REGULATOR receiver
DYB08_RS06340	COG2194	sulfuric ester hydrolase activity
DYB08_RS06360	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYB08_RS06375	COG2315	Protein conserved in bacteria
DYB08_RS06380	COG0142	geranyltranstransferase activity
DYB08_RS06385	COG2828	Protein conserved in bacteria
DYB08_RS06390	COG1113	amino acid transport
DYB08_RS06410	COG2207	Transcriptional regulator
DYB08_RS06435	COG2249	NAD(P)H dehydrogenase (quinone) activity
DYB08_RS06445	COG0560	Phosphoserine phosphatase
DYB08_RS06455	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYB08_RS06465	COG1530	ribonuclease E activity
DYB08_RS06470	COG0424	maF-like protein
DYB08_RS06475	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DYB08_RS06480	COG1792	Involved in formation and maintenance of cell shape
DYB08_RS06485	COG1077	Cell shape determining protein MreB Mrl
DYB08_RS06490	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DYB08_RS06500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DYB08_RS06530	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
DYB08_RS06535	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DYB08_RS06540	COG1752	Esterase of the alpha-beta hydrolase superfamily
DYB08_RS06545	COG1115	amino acid carrier protein
DYB08_RS06565	COG2814	Major facilitator Superfamily
DYB08_RS06570	COG1289	transmembrane transporter activity
DYB08_RS06580	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
DYB08_RS06620	COG1376	ErfK ybiS ycfS ynhG family protein
DYB08_RS06625	COG2832	Protein of unknown function (DUF454)
DYB08_RS06635	COG5510	response to toxic substance
DYB08_RS06655	COG0840	transmembrane signaling receptor activity
DYB08_RS06705	COG3422	double-strand break repair
DYB08_RS06710	COG2824	Alkylphosphonate utilization operon protein PhnA
DYB08_RS06715	COG3189	MarR family transcriptional regulator
DYB08_RS06725	COG0354	folic acid binding
DYB08_RS06730	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DYB08_RS06740	COG0679	Auxin Efflux Carrier
DYB08_RS06745	COG1902	pentaerythritol trinitrate reductase activity
DYB08_RS06750	COG4772	TonB-dependent receptor
DYB08_RS06755	COG2094	Belongs to the DNA glycosylase MPG family
DYB08_RS06780	COG1217	gtp-binding protein TYPA
DYB08_RS06785	COG2233	PERMEase
DYB08_RS06795	COG0833	amino acid
DYB08_RS06800	COG1690	Belongs to the RtcB family
DYB08_RS06805	COG2885	chlorophyll binding
DYB08_RS06805	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DYB08_RS06815	COG0183	Belongs to the thiolase family
DYB08_RS06835	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYB08_RS06855	COG2207	Transcriptional regulator
DYB08_RS06860	COG0183	Belongs to the thiolase family
DYB08_RS06890	COG1272	protein, Hemolysin III
DYB08_RS06895	COG0477	Major facilitator Superfamily
DYB08_RS06920	COG0450	alkyl hydroperoxide reductase
DYB08_RS06940	COG0285	dihydrofolate synthase activity
DYB08_RS06990	COG2096	Adenosyltransferase
DYB08_RS07010	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DYB08_RS07015	COG0745	RESPONSE REGULATOR receiver
DYB08_RS07020	COG2205	protein histidine kinase activity
DYB08_RS07030	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS07035	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS07045	COG0583	DNA-binding transcription factor activity
DYB08_RS07050	COG0625	glutathione transferase activity
DYB08_RS07115	COG0438	transferase activity, transferring glycosyl groups
DYB08_RS07120	COG0463	Glycosyl transferase, family 2
DYB08_RS07125	COG0726	polysaccharide deacetylase
DYB08_RS07145	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DYB08_RS07150	COG2205	protein histidine kinase activity
DYB08_RS07210	COG1862	Preprotein translocase
DYB08_RS07220	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DYB08_RS07225	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DYB08_RS07235	COG3781	membrane
DYB08_RS07240	COG0613	PHP domain protein
DYB08_RS07250	COG2350	Protein conserved in bacteria
DYB08_RS07280	COG1607	acyl-coa hydrolase
DYB08_RS07340	COG2199	diguanylate cyclase activity
DYB08_RS07350	COG1408	metallophosphoesterase
DYB08_RS07355	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DYB08_RS07365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DYB08_RS07385	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DYB08_RS07390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DYB08_RS07405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DYB08_RS07415	COG2969	positive regulation of protein catabolic process
DYB08_RS07450	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYB08_RS07465	COG1309	transcriptional regulator
DYB08_RS07470	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS07515	COG1183	phosphatidylcholine synthase activity
DYB08_RS07520	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DYB08_RS07550	COG0739	heme binding
DYB08_RS07550	COG0741	lytic transglycosylase activity
DYB08_RS07550	COG1196	nuclear chromosome segregation
DYB08_RS07560	COG1702	phosphate starvation-inducible protein PhoH
DYB08_RS07595	COG1295	ribonuclease BN
DYB08_RS07600	COG0697	spore germination
DYB08_RS07605	COG2169	Transcriptional regulator
DYB08_RS07610	COG0179	Fumarylacetoacetate (FAA) hydrolase
DYB08_RS07655	COG0557	exoribonuclease II activity
DYB08_RS07660	COG0339	signal peptide processing
DYB08_RS07665	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
DYB08_RS07695	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DYB08_RS07700	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS07855	COG0626	cystathionine gamma-synthase activity
DYB08_RS07860	COG0433	COG0433 Predicted ATPase
DYB08_RS07865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DYB08_RS07865	COG1017	nitric oxide dioxygenase activity
DYB08_RS07870	COG1959	2 iron, 2 sulfur cluster binding
DYB08_RS07885	COG1301	dicarboxylic acid transport
DYB08_RS07890	COG1946	Acyl-CoA thioesterase
DYB08_RS07910	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DYB08_RS07915	COG1040	competence protein
DYB08_RS07920	COG0494	nUDIX hydrolase
DYB08_RS07930	COG0598	Magnesium transport protein CorA
DYB08_RS07940	COG2854	intermembrane phospholipid transfer
DYB08_RS07950	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DYB08_RS07955	COG1127	ABC transporter
DYB08_RS07965	COG0513	Belongs to the DEAD box helicase family
DYB08_RS07985	COG0408	coproporphyrinogen oxidase activity
DYB08_RS08000	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS08010	COG1983	PspC domain protein
DYB08_RS08015	COG0517	IMP dehydrogenase activity
DYB08_RS08060	COG0583	DNA-binding transcription factor activity
DYB08_RS08100	COG1012	belongs to the aldehyde dehydrogenase family
DYB08_RS08110	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DYB08_RS08115	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DYB08_RS08120	COG0833	amino acid
DYB08_RS08150	COG1192	Involved in chromosome partitioning
DYB08_RS08155	COG0628	permease
DYB08_RS08165	COG1289	transmembrane transporter activity
DYB08_RS08200	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
DYB08_RS08210	COG0277	FAD linked oxidase domain protein
DYB08_RS08215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DYB08_RS08240	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DYB08_RS08245	COG5380	lipid catabolic process
DYB08_RS08270	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DYB08_RS08320	COG0194	GDP metabolic process
DYB08_RS08335	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYB08_RS08355	COG3307	-O-antigen
DYB08_RS08375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
DYB08_RS08380	COG1704	LemA family
DYB08_RS08390	COG0493	'glutamate synthase
DYB08_RS08395	COG0069	glutamate synthase activity
DYB08_RS08395	COG0067	glutamate synthase
DYB08_RS08395	COG0070	glutamate synthase
DYB08_RS08445	COG2226	methyltransferase
DYB08_RS08460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DYB08_RS08465	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DYB08_RS08510	COG0833	amino acid
DYB08_RS08595	COG0488	(ABC) transporter
DYB08_RS08600	COG2873	o-acetylhomoserine
DYB08_RS08605	COG4221	oxidoreductase activity
DYB08_RS08610	COG0659	secondary active sulfate transmembrane transporter activity
DYB08_RS08635	COG0427	acetyl-CoA hydrolase
DYB08_RS08665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DYB08_RS08695	COG2329	Antibiotic biosynthesis monooxygenase
DYB08_RS08710	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DYB08_RS08775	COG2249	NAD(P)H dehydrogenase (quinone) activity
DYB08_RS08785	COG1733	regulation of RNA biosynthetic process
DYB08_RS08820	COG0667	Aldo Keto reductase
DYB08_RS08840	COG0583	DNA-binding transcription factor activity
DYB08_RS08845	COG2814	Major facilitator Superfamily
DYB08_RS08875	COG1335	isochorismatase
DYB08_RS08885	COG1012	belongs to the aldehyde dehydrogenase family
DYB08_RS08890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DYB08_RS08900	COG1113	amino acid transport
DYB08_RS08935	COG2814	Major facilitator Superfamily
DYB08_RS08945	COG0351	phosphomethylpyrimidine kinase
DYB08_RS08945	COG0352	thiamine-phosphate diphosphorylase activity
DYB08_RS08945	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DYB08_RS08965	COG1309	transcriptional regulator
DYB08_RS08970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DYB08_RS08990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DYB08_RS09000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DYB08_RS09005	COG3162	membrane
DYB08_RS09010	COG0784	Response regulator, receiver
DYB08_RS09010	COG2205	protein histidine kinase activity
DYB08_RS09010	COG2198	Histidine kinase
DYB08_RS09035	COG3328	transposase activity
DYB08_RS09040	COG1522	sequence-specific DNA binding
DYB08_RS09045	COG1335	isochorismatase
DYB08_RS09050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYB08_RS09060	COG0668	transmembrane transport
DYB08_RS09065	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DYB08_RS09070	COG1519	Transferase
DYB08_RS09075	COG1902	pentaerythritol trinitrate reductase activity
DYB08_RS09095	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DYB08_RS09120	COG0426	domain, Protein
DYB08_RS09120	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DYB08_RS09125	COG4774	siderophore transport
DYB08_RS09130	COG2119	membrane
DYB08_RS09140	COG0508	dehydrogenase complex catalyzes the overall conversion of
DYB08_RS09150	COG4942	peptidase
DYB08_RS09165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DYB08_RS09175	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DYB08_RS09195	COG0189	ligase activity
DYB08_RS09215	COG0708	Exodeoxyribonuclease III
DYB08_RS09220	COG1393	Belongs to the ArsC family
DYB08_RS09235	COG3706	GGDEF domain
DYB08_RS09270	COG2351	hydroxyisourate hydrolase activity
DYB08_RS09275	COG2233	PERMEase
DYB08_RS09285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYB08_RS09295	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DYB08_RS09300	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS09310	COG3150	esterase
DYB08_RS09325	COG1388	LysM domain
DYB08_RS09325	COG0791	NLP P60 protein
DYB08_RS09340	COG2918	glutathione biosynthetic process
DYB08_RS09355	COG2733	membrane
DYB08_RS09360	COG0436	Aminotransferase
DYB08_RS09365	COG0534	Mate efflux family protein
DYB08_RS09480	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
DYB08_RS09485	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DYB08_RS09495	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DYB08_RS09500	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DYB08_RS09505	COG0546	phosphoglycolate phosphatase activity
DYB08_RS09515	COG0010	Belongs to the arginase family
DYB08_RS09545	COG2188	Transcriptional regulator
DYB08_RS09555	COG0523	cobalamin synthesis protein
DYB08_RS09565	COG1113	amino acid transport
DYB08_RS09575	COG0625	glutathione transferase activity
DYB08_RS09595	COG1683	Conserved Protein
DYB08_RS09600	COG0534	Mate efflux family protein
DYB08_RS09605	COG0385	Bile acid
DYB08_RS09610	COG1335	isochorismatase
DYB08_RS09615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYB08_RS09635	COG2116	formate transmembrane transporter activity
DYB08_RS09640	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DYB08_RS09645	COG2133	pyrroloquinoline quinone binding
DYB08_RS09650	COG2983	Belongs to the UPF0260 family
DYB08_RS09660	COG0400	carboxylic ester hydrolase activity
DYB08_RS09670	COG1194	a g-specific adenine glycosylase
DYB08_RS09685	COG2818	Glycosylase
DYB08_RS09690	COG1064	alcohol dehydrogenase
DYB08_RS09695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYB08_RS09710	COG0583	DNA-binding transcription factor activity
DYB08_RS09715	COG0656	L-ascorbic acid biosynthetic process
DYB08_RS09720	COG2814	Major facilitator Superfamily
DYB08_RS09755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DYB08_RS09770	COG2233	PERMEase
DYB08_RS09775	COG0583	DNA-binding transcription factor activity
DYB08_RS09800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DYB08_RS09810	COG0733	neurotransmitter:sodium symporter activity
DYB08_RS09855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DYB08_RS09860	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DYB08_RS09865	COG0596	Alpha beta hydrolase
DYB08_RS09890	COG0488	(ABC) transporter
DYB08_RS09895	COG0586	Pfam SNARE associated Golgi protein
DYB08_RS09905	COG0187	DNA topoisomerase II activity
DYB08_RS09915	COG0592	DNA-directed DNA polymerase activity
DYB08_RS09940	COG0706	membrane insertase activity
DYB08_RS09955	COG1230	cation diffusion facilitator family transporter
DYB08_RS09960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DYB08_RS09975	COG0402	S-adenosylhomocysteine deaminase activity
DYB08_RS09985	COG0754	glutathionylspermidine amidase activity
DYB08_RS09995	COG0861	Integral membrane protein TerC family
DYB08_RS10000	COG0671	phosphoesterase, PA-phosphatase related
DYB08_RS10010	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DYB08_RS10030	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DYB08_RS10035	COG2951	lytic endotransglycosylase activity
DYB08_RS10100	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
DYB08_RS10140	COG1047	Peptidyl-prolyl cis-trans
DYB08_RS10150	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DYB08_RS10155	COG0196	riboflavin kinase activity
DYB08_RS10165	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
DYB08_RS10170	COG1309	transcriptional regulator
DYB08_RS10175	COG1116	anion transmembrane transporter activity
DYB08_RS10180	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYB08_RS10185	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYB08_RS10190	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYB08_RS10195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DYB08_RS10215	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS10220	COG0546	phosphoglycolate phosphatase activity
DYB08_RS10275	COG3023	N-Acetylmuramoyl-L-alanine amidase
DYB08_RS10280	COG0728	peptidoglycan biosynthetic process
DYB08_RS10305	COG1596	polysaccharide export
DYB08_RS10310	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DYB08_RS10365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DYB08_RS10370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DYB08_RS10375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DYB08_RS10395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
DYB08_RS10400	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYB08_RS10410	COG2186	Transcriptional regulator
DYB08_RS10420	COG0277	FAD linked oxidase domain protein
DYB08_RS10425	COG1448	Aminotransferase
DYB08_RS10435	COG1802	Transcriptional regulator
DYB08_RS10450	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DYB08_RS10470	COG1051	belongs to the nudix hydrolase family
DYB08_RS10510	COG0564	pseudouridine synthase activity
DYB08_RS10550	COG0251	oxidation-reduction process
DYB08_RS10555	COG1113	amino acid transport
DYB08_RS10560	COG1113	amino acid transport
DYB08_RS10580	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DYB08_RS10585	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS10590	COG1024	Enoyl-CoA hydratase
DYB08_RS10595	COG1024	Enoyl-CoA hydratase
DYB08_RS10600	COG0477	Major facilitator Superfamily
DYB08_RS10605	COG3916	Acyl-homoserine-lactone synthase
DYB08_RS10615	COG2197	response regulator
DYB08_RS10625	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS10630	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
DYB08_RS10630	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DYB08_RS10630	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DYB08_RS10630	COG3321	synthase
DYB08_RS10640	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DYB08_RS10655	COG2267	carboxylic ester hydrolase activity
DYB08_RS10675	COG0271	Belongs to the BolA IbaG family
DYB08_RS10685	COG1192	Involved in chromosome partitioning
DYB08_RS10700	COG0586	Pfam SNARE associated Golgi protein
DYB08_RS10705	COG2259	Doxx family
DYB08_RS10710	COG4399	Belongs to the UPF0754 family
DYB08_RS10715	COG0519	Catalyzes the synthesis of GMP from XMP
DYB08_RS10715	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DYB08_RS10760	COG0281	malic enzyme
DYB08_RS10790	COG1280	lysine exporter protein (LysE YggA)
DYB08_RS10795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DYB08_RS10800	COG1121	(ABC) transporter
DYB08_RS10865	COG0386	Belongs to the glutathione peroxidase family
DYB08_RS10880	COG1309	transcriptional regulator
DYB08_RS10885	COG0697	spore germination
DYB08_RS10895	COG0758	DNA mediated transformation
DYB08_RS10930	COG1309	transcriptional regulator
DYB08_RS10965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
DYB08_RS10975	COG0655	NAD(P)H dehydrogenase (quinone) activity
DYB08_RS11010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DYB08_RS11030	COG1253	flavin adenine dinucleotide binding
DYB08_RS11040	COG2860	membrane
DYB08_RS11045	COG0477	Major facilitator Superfamily
DYB08_RS11055	COG0318	PFAM AMP-dependent synthetase and ligase
DYB08_RS11070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DYB08_RS11085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYB08_RS11095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYB08_RS11100	COG0606	chelatase, subunit chli
DYB08_RS11140	COG0589	response to stress
DYB08_RS11145	COG0659	secondary active sulfate transmembrane transporter activity
DYB08_RS11175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DYB08_RS11225	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYB08_RS11270	COG0589	response to stress
DYB08_RS11275	COG0659	secondary active sulfate transmembrane transporter activity
DYB08_RS11335	COG0606	chelatase, subunit chli
DYB08_RS11345	COG0347	Belongs to the P(II) protein family
DYB08_RS11350	COG0004	ammonium transporteR
DYB08_RS11360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYB08_RS11360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DYB08_RS11400	COG0795	lipopolysaccharide-transporting ATPase activity
DYB08_RS11405	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DYB08_RS11410	COG0793	Belongs to the peptidase S41A family
DYB08_RS11425	COG2197	response regulator
DYB08_RS11435	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
DYB08_RS11445	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DYB08_RS11450	COG4974	Belongs to the 'phage' integrase family
DYB08_RS11475	COG0772	Belongs to the SEDS family
DYB08_RS11480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DYB08_RS11485	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DYB08_RS11490	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
DYB08_RS11515	COG0697	spore germination
DYB08_RS11520	COG1538	Outer membrane efflux protein
DYB08_RS11540	COG3275	phosphorelay sensor kinase activity
DYB08_RS11550	COG0181	hydroxymethylbilane synthase activity
DYB08_RS11595	COG1716	ATPase activity
DYB08_RS11600	COG0546	phosphoglycolate phosphatase activity
DYB08_RS11705	COG0596	Alpha beta hydrolase
DYB08_RS11710	COG2056	Na+-H+ antiporter family
DYB08_RS11725	COG0326	Molecular chaperone. Has ATPase activity
DYB08_RS11740	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
DYB08_RS11810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DYB08_RS11815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DYB08_RS11815	COG2169	Transcriptional regulator
DYB08_RS11845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DYB08_RS11855	COG0497	DNA recombination
DYB08_RS11870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DYB08_RS11880	COG0237	dephospho-CoA kinase activity
DYB08_RS11930	COG0195	Participates in both transcription termination and antitermination
DYB08_RS11945	COG1320	monovalent cation:proton antiporter activity
DYB08_RS11950	COG2212	antiporter activity
DYB08_RS11955	COG1863	multisubunit Na H antiporter MnhE subunit
DYB08_RS11960	COG0651	ATP synthesis coupled electron transport
DYB08_RS11965	COG1006	Multisubunit Na H antiporter MnhC subunit
DYB08_RS11970	COG2111	Na H antiporter
DYB08_RS11970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DYB08_RS11985	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DYB08_RS11990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYB08_RS12005	COG2226	methyltransferase
DYB08_RS12025	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DYB08_RS12030	COG1074	ATP-dependent DNA helicase activity
DYB08_RS12035	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DYB08_RS12040	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
DYB08_RS12055	COG0598	Magnesium transport protein CorA
DYB08_RS12060	COG0789	Transcriptional regulator
DYB08_RS12065	COG0484	heat shock protein binding
DYB08_RS12075	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DYB08_RS12080	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DYB08_RS12080	COG0475	glutathione-regulated potassium exporter activity
DYB08_RS12085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DYB08_RS12110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYB08_RS12120	COG4535	Mg2 and Co2 transporter CorC
DYB08_RS12125	COG0425	Belongs to the sulfur carrier protein TusA family
DYB08_RS12130	COG0644	oxidoreductase
DYB08_RS12130	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
DYB08_RS12140	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DYB08_RS12155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DYB08_RS12160	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DYB08_RS12200	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DYB08_RS12215	COG0534	Mate efflux family protein
DYB08_RS12225	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DYB08_RS12230	COG4221	oxidoreductase activity
DYB08_RS12235	COG0583	DNA-binding transcription factor activity
DYB08_RS12250	COG0318	PFAM AMP-dependent synthetase and ligase
DYB08_RS12255	COG1530	ribonuclease E activity
DYB08_RS12270	COG0546	phosphoglycolate phosphatase activity
DYB08_RS12275	COG2378	regulation of single-species biofilm formation
DYB08_RS12280	COG0625	glutathione transferase activity
DYB08_RS12290	COG0583	DNA-binding transcription factor activity
DYB08_RS12355	COG0473	3-isopropylmalate dehydrogenase activity
DYB08_RS12410	COG1301	dicarboxylic acid transport
DYB08_RS12420	COG1560	Kdo2-lipid A biosynthetic process
DYB08_RS12425	COG1280	lysine exporter protein (LysE YggA)
DYB08_RS12430	COG0488	(ABC) transporter
DYB08_RS12435	COG2900	Belongs to the SlyX family
DYB08_RS12445	COG1733	regulation of RNA biosynthetic process
DYB08_RS12470	COG0210	DNA helicase
DYB08_RS12475	COG0724	RNA recognition motif
DYB08_RS12495	COG4651	solute:proton antiporter activity
DYB08_RS12495	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DYB08_RS12520	COG0788	formyltetrahydrofolate deformylase activity
DYB08_RS12620	COG2813	Specifically methylates the guanine in position
DYB08_RS12620	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DYB08_RS12630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DYB08_RS12640	COG4774	siderophore transport
DYB08_RS12650	COG0740	serine-type endopeptidase activity
DYB08_RS12670	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
DYB08_RS12670	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DYB08_RS12675	COG0280	phosphate acetyltransferase
DYB08_RS12675	COG0857	belongs to the CobB CobQ family
DYB08_RS12680	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DYB08_RS12695	COG0800	Aldolase
DYB08_RS12705	COG3265	gluconokinase activity
DYB08_RS12710	COG1012	belongs to the aldehyde dehydrogenase family
DYB08_RS12720	COG2267	carboxylic ester hydrolase activity
DYB08_RS12735	COG0793	Belongs to the peptidase S41A family
DYB08_RS12770	COG1426	Protein conserved in bacteria
DYB08_RS12815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DYB08_RS12825	COG0318	PFAM AMP-dependent synthetase and ligase
DYB08_RS12840	COG2986	histidine ammonia-lyase
DYB08_RS12890	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS12895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DYB08_RS12915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
DYB08_RS12925	COG1162	GTPase activity
DYB08_RS12930	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DYB08_RS12945	COG1538	Outer membrane efflux protein
DYB08_RS12950	COG0577	efflux transmembrane transporter activity
DYB08_RS12950	COG1136	(ABC) transporter
DYB08_RS12990	COG0028	Belongs to the TPP enzyme family
DYB08_RS12995	COG0440	acetolactate synthase activity
DYB08_RS13035	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DYB08_RS13050	COG0084	hydrolase, TatD family'
DYB08_RS13065	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DYB08_RS13075	COG0583	DNA-binding transcription factor activity
DYB08_RS13085	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYB08_RS13090	COG2814	Major facilitator Superfamily
DYB08_RS13100	COG0697	spore germination
DYB08_RS13130	COG3622	Belongs to the hyi family
DYB08_RS13135	COG2084	Dehydrogenase
DYB08_RS13140	COG1024	Enoyl-CoA hydratase
DYB08_RS13145	COG0784	Response regulator, receiver
DYB08_RS13145	COG2205	protein histidine kinase activity
DYB08_RS13145	COG5002	protein histidine kinase activity
DYB08_RS13165	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DYB08_RS13175	COG3956	TIGRFAM MazG family protein
DYB08_RS13180	COG1555	photosystem II stabilization
DYB08_RS13185	COG0617	tRNA 3'-terminal CCA addition
DYB08_RS13190	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
DYB08_RS13210	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DYB08_RS13215	COG3028	Belongs to the UPF0307 family
DYB08_RS13220	COG0318	PFAM AMP-dependent synthetase and ligase
DYB08_RS13240	COG0625	glutathione transferase activity
DYB08_RS13245	COG1238	metal cluster binding
DYB08_RS13285	COG0072	phenylalanine-tRNA ligase activity
DYB08_RS13315	COG0248	Ppx GppA phosphatase
DYB08_RS13325	COG0037	tRNA processing
DYB08_RS13365	COG1764	response to oxidative stress
DYB08_RS13370	COG1846	Transcriptional regulator
DYB08_RS13380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYB08_RS13440	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DYB08_RS13445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DYB08_RS13450	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DYB08_RS13460	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DYB08_RS13510	COG1214	PFAM Peptidase M22, glycoprotease
DYB08_RS13535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DYB08_RS13540	COG0561	phosphatase activity
DYB08_RS13550	COG2132	Multicopper oxidase
DYB08_RS13555	COG3667	copper resistance
DYB08_RS13570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DYB08_RS13575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DYB08_RS13580	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DYB08_RS13610	COG1063	alcohol dehydrogenase
DYB08_RS13615	COG0583	DNA-binding transcription factor activity
DYB08_RS13620	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS13630	COG2814	Major facilitator Superfamily
DYB08_RS13635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DYB08_RS13645	COG1053	succinate dehydrogenase
DYB08_RS13650	COG0583	DNA-binding transcription factor activity
DYB08_RS13675	COG0583	DNA-binding transcription factor activity
DYB08_RS13705	COG0583	DNA-binding transcription factor activity
DYB08_RS13720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DYB08_RS13750	COG0384	phenazine biosynthesis protein PhzF
DYB08_RS13770	COG4993	Dehydrogenase
DYB08_RS13855	COG2205	protein histidine kinase activity
DYB08_RS13865	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DYB08_RS13885	COG0745	RESPONSE REGULATOR receiver
DYB08_RS13925	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
DYB08_RS13955	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DYB08_RS13960	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DYB08_RS13980	COG0583	DNA-binding transcription factor activity
DYB08_RS14000	COG0668	transmembrane transport
DYB08_RS14010	COG2081	HI0933 family
DYB08_RS14015	COG2515	1-aminocyclopropane-1-carboxylate deaminase
DYB08_RS14045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYB08_RS14045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DYB08_RS14055	COG0489	protein tyrosine kinase activity
DYB08_RS14115	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DYB08_RS14125	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DYB08_RS14140	COG0730	response to heat
DYB08_RS14150	COG1196	nuclear chromosome segregation
DYB08_RS14170	COG2223	nitrite transmembrane transporter activity
DYB08_RS14175	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
DYB08_RS14180	COG1877	trehalose-phosphatase activity
DYB08_RS14185	COG2226	methyltransferase
DYB08_RS14185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DYB08_RS14185	COG0596	Alpha beta hydrolase
DYB08_RS14200	COG4106	trans-aconitate 2-methyltransferase activity
DYB08_RS14215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DYB08_RS14220	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DYB08_RS14225	COG0009	L-threonylcarbamoyladenylate synthase
DYB08_RS14230	COG3101	peptidyl-lysine hydroxylation
DYB08_RS14235	COG1399	metal-binding, possibly nucleic acid-binding protein
DYB08_RS14260	COG1652	LysM domain
DYB08_RS14265	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DYB08_RS14265	COG0352	thiamine-phosphate diphosphorylase activity
DYB08_RS14265	COG0351	phosphomethylpyrimidine kinase
DYB08_RS14275	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DYB08_RS14305	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DYB08_RS14335	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DYB08_RS14350	COG0358	DNA primase activity
DYB08_RS14360	COG0564	pseudouridine synthase activity
DYB08_RS14385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DYB08_RS14405	COG0583	DNA-binding transcription factor activity
DYB08_RS14410	COG0473	3-isopropylmalate dehydrogenase activity
DYB08_RS14440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DYB08_RS14440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DYB08_RS14455	COG1981	membrane
DYB08_RS14500	COG0456	acetyltransferase
DYB08_RS14510	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DYB08_RS14515	COG0492	ferredoxin-NADP+ reductase activity
DYB08_RS14520	COG1674	ftsk spoiiie
DYB08_RS14520	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
DYB08_RS14525	COG1280	lysine exporter protein (LysE YggA)
DYB08_RS14550	COG2894	cell division
DYB08_RS14565	COG0204	Acyl-transferase
DYB08_RS14570	COG2885	chlorophyll binding
DYB08_RS14575	COG0210	DNA helicase
DYB08_RS14585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DYB08_RS14600	COG0121	glutamine amidotransferase
DYB08_RS14625	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DYB08_RS14630	COG0735	belongs to the Fur family
DYB08_RS14655	COG0420	3'-5' exonuclease activity
DYB08_RS14675	COG1090	epimerase
DYB08_RS14690	COG2050	protein possibly involved in aromatic compounds catabolism
DYB08_RS14700	COG2814	Major facilitator Superfamily
DYB08_RS14705	COG0405	Gamma-glutamyltransferase
DYB08_RS14770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYB08_RS14860	COG1484	DNA-dependent DNA replication
DYB08_RS15055	COG2026	Addiction module toxin, RelE StbE family
DYB08_RS15095	COG0592	DNA-directed DNA polymerase activity
DYB08_RS15235	COG0477	Major facilitator Superfamily
DYB08_RS15240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYB08_RS15250	COG1595	DNA-templated transcription, initiation
DYB08_RS15305	COG0531	amino acid
DYB08_RS15310	COG2040	homocysteine
DYB08_RS15335	COG1309	transcriptional regulator
DYB08_RS15340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DYB08_RS15345	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
DYB08_RS15355	COG1607	acyl-coa hydrolase
DYB08_RS15365	COG0523	cobalamin synthesis protein
DYB08_RS15375	COG4681	YaeQ
DYB08_RS15385	COG0726	polysaccharide deacetylase
DYB08_RS15385	COG1649	PFAM Uncharacterised BCR, COG1649
DYB08_RS15390	COG1215	transferase activity, transferring glycosyl groups
DYB08_RS15400	COG1024	Enoyl-CoA hydratase
DYB08_RS15415	COG1414	Transcriptional regulator
DYB08_RS15435	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS15445	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYB08_RS15450	COG2271	Major facilitator Superfamily
DYB08_RS15460	COG2267	carboxylic ester hydrolase activity
DYB08_RS15465	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS15480	COG0028	Belongs to the TPP enzyme family
DYB08_RS15490	COG0477	Major facilitator Superfamily
DYB08_RS15495	COG0242	peptide deformylase activity
DYB08_RS15500	COG2066	Belongs to the glutaminase family
DYB08_RS15505	COG2207	Transcriptional regulator
DYB08_RS15510	COG2223	nitrite transmembrane transporter activity
DYB08_RS15530	COG0583	DNA-binding transcription factor activity
DYB08_RS15535	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS15540	COG2271	Major facilitator Superfamily
DYB08_RS15545	COG3959	Transketolase, thiamine diphosphate binding domain
DYB08_RS15550	COG3958	Transketolase
DYB08_RS15560	COG0306	phosphate transporter
DYB08_RS15580	COG1262	PFAM Formylglycine-generating sulfatase enzyme
DYB08_RS15625	COG4181	ATPase activity
DYB08_RS15630	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DYB08_RS15655	COG0583	DNA-binding transcription factor activity
DYB08_RS15665	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DYB08_RS15670	COG1773	rubredoxin
DYB08_RS15720	COG2851	Citrate transporter
DYB08_RS15730	COG1253	flavin adenine dinucleotide binding
DYB08_RS15770	COG0804	urea catabolic process
DYB08_RS15780	COG0830	nickel cation binding
DYB08_RS15795	COG0742	ribosomal rna small subunit methyltransferase
DYB08_RS15800	COG0768	penicillin binding
DYB08_RS15825	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DYB08_RS15830	COG2878	Part of a membrane complex involved in electron transport
DYB08_RS15835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DYB08_RS15845	COG3384	dioxygenase
DYB08_RS15875	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DYB08_RS16200	COG0739	heme binding
DYB08_RS16255	COG2194	sulfuric ester hydrolase activity
DYB08_RS16290	COG0006	proline dipeptidase activity
DYB08_RS16295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYB08_RS16300	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYB08_RS16320	COG1279	arginine transmembrane transporter activity
DYB08_RS16325	COG0583	DNA-binding transcription factor activity
DYB08_RS16365	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYB08_RS16370	COG0741	lytic transglycosylase activity
DYB08_RS16370	COG1388	LysM domain
DYB08_RS16370	COG0741	lytic transglycosylase activity
DYB08_RS16370	COG1388	LysM domain
DYB08_RS16380	COG4174	ABC transporter (Permease)
DYB08_RS16385	COG4239	(ABC) transporter, permease
DYB08_RS16390	COG4172	Belongs to the ABC transporter superfamily
DYB08_RS16410	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DYB08_RS16420	COG3706	GGDEF domain
DYB08_RS16420	COG2203	Gaf domain
DYB08_RS16420	COG4251	negative regulation of phosphorylation
DYB08_RS16420	COG5001	Diguanylate cyclase
DYB08_RS16430	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYB08_RS16430	COG1902	pentaerythritol trinitrate reductase activity
DYB08_RS16520	COG0300	oxidoreductase activity
DYB08_RS16530	COG1309	transcriptional regulator
DYB08_RS16535	COG1741	Belongs to the pirin family
DYB08_RS16550	COG2072	flavoprotein involved in K transport
DYB08_RS16560	COG2252	PERMEase
DYB08_RS16565	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DYB08_RS16570	COG3038	cytochrome b561
DYB08_RS16580	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DYB08_RS16590	COG0527	aspartate kinase activity
DYB08_RS16600	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DYB08_RS16610	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DYB08_RS16625	COG0667	Aldo Keto reductase
DYB08_RS16640	COG1765	OsmC-like protein
DYB08_RS16655	COG0542	response to heat
DYB08_RS16690	COG2885	chlorophyll binding
DYB08_RS16700	COG0625	glutathione transferase activity
DYB08_RS16705	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DYB08_RS16725	COG3634	alkyl hydroperoxide reductase activity
DYB08_RS16735	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DYB08_RS16745	COG0450	alkyl hydroperoxide reductase
DYB08_RS16750	COG1643	Atp-dependent helicase
DYB08_RS16765	COG2814	Major facilitator Superfamily
DYB08_RS16770	COG3135	benzoate transporter
DYB08_RS16775	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS16780	COG0633	Ferredoxin
DYB08_RS16780	COG0543	2 iron, 2 sulfur cluster binding
DYB08_RS16785	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
DYB08_RS16790	COG4638	Rieske (2fe-2S)
DYB08_RS16795	COG0583	DNA-binding transcription factor activity
DYB08_RS16850	COG1570	exodeoxyribonuclease VII activity
DYB08_RS16885	COG1280	lysine exporter protein (LysE YggA)
DYB08_RS16890	COG1278	Cold shock
DYB08_RS16940	COG2814	Major facilitator Superfamily
DYB08_RS17160	COG5410	chromosome segregation
DYB08_RS17335	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
DYB08_RS17335	COG0517	IMP dehydrogenase activity
DYB08_RS17340	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DYB08_RS17350	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DYB08_RS17355	COG1137	ATPase activity
DYB08_RS17360	COG1538	Outer membrane efflux protein
DYB08_RS17390	COG4122	O-methyltransferase activity
DYB08_RS17400	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
DYB08_RS17415	COG1522	sequence-specific DNA binding
DYB08_RS17420	COG5006	permease, DMT superfamily
DYB08_RS17430	COG1560	Kdo2-lipid A biosynthetic process
DYB08_RS17445	COG2814	Major facilitator Superfamily
DYB08_RS17465	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYB08_RS17520	COG0583	DNA-binding transcription factor activity
DYB08_RS17525	COG1914	H( )-stimulated, divalent metal cation uptake system
DYB08_RS17545	COG4770	biotin carboxylase activity
DYB08_RS17550	COG0038	chloride channel
DYB08_RS17575	COG1309	transcriptional regulator
DYB08_RS17585	COG1063	alcohol dehydrogenase
DYB08_RS17600	COG0439	Biotin carboxylase
DYB08_RS17605	COG2249	NAD(P)H dehydrogenase (quinone) activity
DYB08_RS17625	COG0864	Transcriptional regulator
DYB08_RS17635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYB08_RS17640	COG1116	anion transmembrane transporter activity
DYB08_RS17765	COG0590	tRNA wobble adenosine to inosine editing
DYB08_RS17770	COG2807	transmembrane transport
DYB08_RS17785	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
DYB08_RS17800	COG0789	Transcriptional regulator
DYB08_RS17815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DYB08_RS17835	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DYB08_RS17845	COG0446	pyridine nucleotide-disulphide oxidoreductase
DYB08_RS17860	COG1012	belongs to the aldehyde dehydrogenase family
DYB08_RS17865	COG0531	amino acid
DYB08_RS17870	COG1760	l-serine dehydratase
DYB08_RS17875	COG1012	belongs to the aldehyde dehydrogenase family
DYB08_RS17875	COG2030	dehydratase
DYB08_RS17880	COG3396	Phenylacetate-CoA oxygenase
DYB08_RS17885	COG3460	Phenylacetate-CoA oxygenase
DYB08_RS17890	COG3396	Phenylacetate-CoA oxygenase
DYB08_RS17895	COG2151	metal-sulfur cluster biosynthetic enzyme
DYB08_RS17900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DYB08_RS17905	COG1024	Enoyl-CoA hydratase
DYB08_RS17910	COG1024	Enoyl-CoA hydratase
DYB08_RS17915	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYB08_RS17920	COG0183	Belongs to the thiolase family
DYB08_RS17925	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
DYB08_RS17930	COG3327	negative regulation of DNA-templated transcription, initiation
DYB08_RS17940	COG2050	protein possibly involved in aromatic compounds catabolism
DYB08_RS17980	COG0753	catalase activity
DYB08_RS17985	COG3038	cytochrome b561
DYB08_RS18005	COG2267	carboxylic ester hydrolase activity
DYB08_RS18010	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DYB08_RS18015	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DYB08_RS18020	COG1012	belongs to the aldehyde dehydrogenase family
DYB08_RS18030	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DYB08_RS18040	COG1012	belongs to the aldehyde dehydrogenase family
DYB08_RS18045	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DYB08_RS18050	COG0583	DNA-binding transcription factor activity
DYB08_RS18060	COG1414	Transcriptional regulator
DYB08_RS18065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DYB08_RS18075	COG1840	ABC-type Fe3 transport system, periplasmic component
DYB08_RS18080	COG3842	ATPase activity
DYB08_RS18095	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
DYB08_RS18100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DYB08_RS18105	COG2814	Major facilitator Superfamily
DYB08_RS18110	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS18135	COG1024	Enoyl-CoA hydratase
DYB08_RS18145	COG2814	Major facilitator Superfamily
DYB08_RS18155	COG0183	Belongs to the thiolase family
DYB08_RS18160	COG1250	3-hydroxyacyl-CoA dehydrogenase
DYB08_RS18165	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS18170	COG1024	Enoyl-CoA hydratase
DYB08_RS18175	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS18180	COG2814	Major facilitator Superfamily
DYB08_RS18185	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
DYB08_RS18190	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
DYB08_RS18200	COG2814	Major facilitator Superfamily
DYB08_RS18210	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS18225	COG0583	DNA-binding transcription factor activity
DYB08_RS18235	COG4770	biotin carboxylase activity
DYB08_RS18240	COG1024	Enoyl-CoA hydratase
DYB08_RS18245	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DYB08_RS18250	COG1960	acyl-CoA dehydrogenase activity
DYB08_RS18255	COG1309	transcriptional regulator
DYB08_RS18260	COG0318	PFAM AMP-dependent synthetase and ligase
DYB08_RS18280	COG0583	DNA-binding transcription factor activity
DYB08_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
DYB08_RS18345	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DYB08_RS18365	COG0784	Response regulator, receiver
DYB08_RS18365	COG2205	protein histidine kinase activity
DYB08_RS18385	COG0765	amino acid transport
DYB08_RS18390	COG0765	amino acid transport
DYB08_RS18395	COG1126	abc transporter atp-binding protein
DYB08_RS18400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYB08_RS18405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DYB08_RS18420	COG1280	lysine exporter protein (LysE YggA)
DYB08_RS18430	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DYB08_RS18435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DYB08_RS18440	COG1045	serine acetyltransferase
DYB08_RS18455	COG0583	DNA-binding transcription factor activity
DYB08_RS18460	COG0625	glutathione transferase activity
DYB08_RS18465	COG0625	glutathione transferase activity
DYB08_RS18470	COG0583	DNA-binding transcription factor activity
DYB08_RS18480	COG1346	cytolysis
DYB08_RS18500	COG2814	Major facilitator Superfamily
DYB08_RS18510	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
DYB08_RS18515	COG3052	prosthetic group binding
DYB08_RS18535	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DYB08_RS18555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DYB08_RS18565	COG1294	oxidase, subunit
DYB08_RS18570	COG1271	oxidase subunit
DYB08_RS18595	COG0477	Major facilitator Superfamily
DYB08_RS18620	COG4521	taurine ABC transporter
DYB08_RS18625	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DYB08_RS18630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DYB08_RS18635	COG2175	clavaminate synthase activity
DYB08_RS18645	COG1953	Uracil, thiamine, allantoin
DYB08_RS18655	COG0583	DNA-binding transcription factor activity
DYB08_RS18665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
DYB08_RS18680	COG0640	Transcriptional regulator
DYB08_RS18685	COG0798	PFAM Bile acid sodium symporter
DYB08_RS18690	COG0583	DNA-binding transcription factor activity
DYB08_RS18705	COG3634	alkyl hydroperoxide reductase activity
DYB08_RS18760	COG0436	Aminotransferase
DYB08_RS18770	COG0386	Belongs to the glutathione peroxidase family
DYB08_RS18810	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
DYB08_RS18835	COG0012	GTP binding
DYB08_RS18840	COG2011	ABC-type metal ion transport system permease component
DYB08_RS18845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYB08_RS18855	COG1464	Belongs to the NlpA lipoprotein family
DYB08_RS18885	COG0765	amino acid transport
DYB08_RS18890	COG0765	amino acid transport
DYB08_RS18895	COG1126	abc transporter atp-binding protein
DYB08_RS18905	COG1522	sequence-specific DNA binding
DYB08_RS18920	COG1309	transcriptional regulator
DYB08_RS18945	COG0583	DNA-binding transcription factor activity
DYB08_RS18955	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
DYB08_RS18965	COG0697	spore germination
DYB08_RS18995	COG3121	Chaperone
DYB08_RS19000	COG3539	Fimbrial protein
DYB08_RS19025	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DYB08_RS19025	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DYB08_RS19070	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DYB08_RS19080	COG2353	YceI-like domain
DYB08_RS19090	COG3698	Phosphodiester glycosidase
DYB08_RS19105	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
DYB08_RS19110	COG0506	proline dehydrogenase activity
DYB08_RS19110	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DYB08_RS19110	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DYB08_RS19120	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DYB08_RS19125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DYB08_RS19145	COG1132	(ABC) transporter
DYB08_RS19150	COG3122	Protein conserved in bacteria
DYB08_RS19155	COG3619	membrane
DYB08_RS19175	COG0640	Transcriptional regulator
DYB08_RS19185	COG2850	peptidyl-arginine hydroxylation
DYB08_RS19190	COG0424	maF-like protein
DYB08_RS19210	COG0191	fructose-bisphosphate aldolase activity
DYB08_RS19215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DYB08_RS19230	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DYB08_RS19240	COG1192	Involved in chromosome partitioning
DYB08_RS19245	COG1475	DNA binding
DYB08_RS19250	COG0811	peptide transport
DYB08_RS19260	COG1132	(ABC) transporter
DYB08_RS19265	COG1663	tetraacyldisaccharide 4'-kinase activity
DYB08_RS19285	COG0084	hydrolase, TatD family'
DYB08_RS19350	COG0776	regulation of translation
DYB08_RS19395	COG0791	NLP P60 protein
DYB08_RS19505	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DYB08_RS19510	COG1475	DNA binding
DYB08_RS19715	COG0488	(ABC) transporter
DYB08_RS19720	COG3173	Aminoglycoside phosphotransferase
DYB08_RS19790	COG0756	dUTP diphosphatase activity
DYB08_RS19815	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DYB08_RS19820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DYB08_RS19820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DYB08_RS19845	COG0419	ATPase involved in DNA repair
DYB08_RS19890	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DYB08_RS19945	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DYB08_RS19970	COG0194	GDP metabolic process
DYB08_RS20010	COG0358	DNA primase activity
DYB08_RS20085	COG4683	PFAM Phage derived protein Gp49-like (DUF891)