locus-tag	class	description
EGM95_RS00010	COG0592	DNA-directed DNA polymerase activity
EGM95_RS00020	COG0187	DNA topoisomerase II activity
EGM95_RS00030	COG0586	Pfam SNARE associated Golgi protein
EGM95_RS00035	COG0488	(ABC) transporter
EGM95_RS00060	COG0596	Alpha beta hydrolase
EGM95_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EGM95_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGM95_RS00115	COG0733	neurotransmitter:sodium symporter activity
EGM95_RS00150	COG0583	DNA-binding transcription factor activity
EGM95_RS00155	COG2233	PERMEase
EGM95_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM95_RS00205	COG2814	Major facilitator Superfamily
EGM95_RS00210	COG0656	L-ascorbic acid biosynthetic process
EGM95_RS00215	COG0583	DNA-binding transcription factor activity
EGM95_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGM95_RS00235	COG1064	alcohol dehydrogenase
EGM95_RS00240	COG2818	Glycosylase
EGM95_RS00255	COG1194	a g-specific adenine glycosylase
EGM95_RS00275	COG2983	Belongs to the UPF0260 family
EGM95_RS00280	COG2133	pyrroloquinoline quinone binding
EGM95_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EGM95_RS00290	COG2116	formate transmembrane transporter activity
EGM95_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGM95_RS00315	COG1335	isochorismatase
EGM95_RS00320	COG0385	Bile acid
EGM95_RS00325	COG0534	Mate efflux family protein
EGM95_RS00330	COG1683	Conserved Protein
EGM95_RS00350	COG0625	glutathione transferase activity
EGM95_RS00360	COG1113	amino acid transport
EGM95_RS00370	COG0523	cobalamin synthesis protein
EGM95_RS00380	COG2188	Transcriptional regulator
EGM95_RS00410	COG0010	Belongs to the arginase family
EGM95_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGM95_RS00520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EGM95_RS00530	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EGM95_RS00535	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EGM95_RS00625	COG0534	Mate efflux family protein
EGM95_RS00630	COG0436	Aminotransferase
EGM95_RS00635	COG2733	membrane
EGM95_RS00650	COG2918	glutathione biosynthetic process
EGM95_RS00700	COG3150	esterase
EGM95_RS00710	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EGM95_RS00720	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM95_RS00730	COG2233	PERMEase
EGM95_RS00735	COG2351	hydroxyisourate hydrolase activity
EGM95_RS00770	COG3706	GGDEF domain
EGM95_RS00785	COG1393	Belongs to the ArsC family
EGM95_RS00790	COG0708	Exodeoxyribonuclease III
EGM95_RS00805	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
EGM95_RS00825	COG0189	ligase activity
EGM95_RS00845	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EGM95_RS00855	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EGM95_RS00870	COG4942	peptidase
EGM95_RS00880	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGM95_RS00890	COG2119	membrane
EGM95_RS00895	COG4774	siderophore transport
EGM95_RS00900	COG0426	domain, Protein
EGM95_RS00900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGM95_RS00930	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EGM95_RS00950	COG1902	pentaerythritol trinitrate reductase activity
EGM95_RS00955	COG1519	Transferase
EGM95_RS00960	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGM95_RS00965	COG0668	transmembrane transport
EGM95_RS00975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGM95_RS00980	COG1335	isochorismatase
EGM95_RS00985	COG1522	sequence-specific DNA binding
EGM95_RS01010	COG0784	Response regulator, receiver
EGM95_RS01010	COG2198	Histidine kinase
EGM95_RS01010	COG2205	protein histidine kinase activity
EGM95_RS01015	COG3162	membrane
EGM95_RS01020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGM95_RS01030	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGM95_RS01045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EGM95_RS01050	COG1309	transcriptional regulator
EGM95_RS01070	COG0351	phosphomethylpyrimidine kinase
EGM95_RS01070	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGM95_RS01070	COG0352	thiamine-phosphate diphosphorylase activity
EGM95_RS01080	COG2814	Major facilitator Superfamily
EGM95_RS01095	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGM95_RS01105	COG1113	amino acid transport
EGM95_RS01115	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGM95_RS01120	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS01130	COG1335	isochorismatase
EGM95_RS01160	COG2508	Transcriptional regulator
EGM95_RS01160	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EGM95_RS01180	COG1113	amino acid transport
EGM95_RS01190	COG2814	Major facilitator Superfamily
EGM95_RS01195	COG0583	DNA-binding transcription factor activity
EGM95_RS01215	COG0667	Aldo Keto reductase
EGM95_RS01250	COG1733	regulation of RNA biosynthetic process
EGM95_RS01260	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGM95_RS01290	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS01350	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGM95_RS01420	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EGM95_RS01435	COG2329	Antibiotic biosynthesis monooxygenase
EGM95_RS01465	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EGM95_RS01495	COG0427	acetyl-CoA hydrolase
EGM95_RS01520	COG0659	secondary active sulfate transmembrane transporter activity
EGM95_RS01525	COG4221	oxidoreductase activity
EGM95_RS01535	COG0488	(ABC) transporter
EGM95_RS01600	COG0833	amino acid
EGM95_RS01645	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EGM95_RS01650	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EGM95_RS01665	COG2226	methyltransferase
EGM95_RS01715	COG0069	glutamate synthase activity
EGM95_RS01715	COG0067	glutamate synthase
EGM95_RS01715	COG0070	glutamate synthase
EGM95_RS01720	COG0493	'glutamate synthase
EGM95_RS01730	COG1704	LemA family
EGM95_RS01735	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EGM95_RS01755	COG3307	-O-antigen
EGM95_RS01775	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGM95_RS01790	COG0194	GDP metabolic process
EGM95_RS01840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EGM95_RS01860	COG5380	lipid catabolic process
EGM95_RS01865	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EGM95_RS01890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EGM95_RS01895	COG0277	FAD linked oxidase domain protein
EGM95_RS01905	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS01920	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EGM95_RS01925	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGM95_RS01940	COG1289	transmembrane transporter activity
EGM95_RS01950	COG0628	permease
EGM95_RS01955	COG1192	Involved in chromosome partitioning
EGM95_RS01985	COG0833	amino acid
EGM95_RS01990	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGM95_RS01995	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGM95_RS02005	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS02045	COG0583	DNA-binding transcription factor activity
EGM95_RS02065	COG1106	Psort location Cytoplasmic, score
EGM95_RS02100	COG0517	IMP dehydrogenase activity
EGM95_RS02105	COG1983	PspC domain protein
EGM95_RS02115	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS02130	COG0408	coproporphyrinogen oxidase activity
EGM95_RS02150	COG0513	Belongs to the DEAD box helicase family
EGM95_RS02160	COG1127	ABC transporter
EGM95_RS02165	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EGM95_RS02175	COG2854	intermembrane phospholipid transfer
EGM95_RS02185	COG0598	Magnesium transport protein CorA
EGM95_RS02195	COG0494	nUDIX hydrolase
EGM95_RS02200	COG1040	competence protein
EGM95_RS02205	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EGM95_RS02225	COG1946	Acyl-CoA thioesterase
EGM95_RS02230	COG1301	dicarboxylic acid transport
EGM95_RS02245	COG1959	2 iron, 2 sulfur cluster binding
EGM95_RS02250	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGM95_RS02250	COG1017	nitric oxide dioxygenase activity
EGM95_RS02255	COG0433	COG0433 Predicted ATPase
EGM95_RS02260	COG0626	cystathionine gamma-synthase activity
EGM95_RS02415	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS02420	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EGM95_RS02450	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EGM95_RS02455	COG0339	signal peptide processing
EGM95_RS02460	COG0557	exoribonuclease II activity
EGM95_RS02505	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGM95_RS02515	COG0697	spore germination
EGM95_RS02520	COG1295	ribonuclease BN
EGM95_RS02555	COG1702	phosphate starvation-inducible protein PhoH
EGM95_RS02565	COG1196	nuclear chromosome segregation
EGM95_RS02565	COG0741	lytic transglycosylase activity
EGM95_RS02565	COG0739	heme binding
EGM95_RS02595	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EGM95_RS02600	COG1183	phosphatidylcholine synthase activity
EGM95_RS02650	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS02655	COG1309	transcriptional regulator
EGM95_RS02670	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGM95_RS02675	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS02695	COG2969	positive regulation of protein catabolic process
EGM95_RS02705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EGM95_RS02720	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EGM95_RS02725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EGM95_RS02745	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EGM95_RS02755	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGM95_RS02760	COG1408	metallophosphoesterase
EGM95_RS02770	COG2199	diguanylate cyclase activity
EGM95_RS02830	COG1607	acyl-coa hydrolase
EGM95_RS02860	COG2350	Protein conserved in bacteria
EGM95_RS02870	COG0613	PHP domain protein
EGM95_RS02875	COG3781	membrane
EGM95_RS02885	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EGM95_RS02890	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EGM95_RS02900	COG1862	Preprotein translocase
EGM95_RS02960	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EGM95_RS02980	COG0726	polysaccharide deacetylase
EGM95_RS02985	COG0463	Glycosyl transferase, family 2
EGM95_RS02990	COG0438	transferase activity, transferring glycosyl groups
EGM95_RS03020	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS03075	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS03080	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS03090	COG2205	protein histidine kinase activity
EGM95_RS03095	COG0745	RESPONSE REGULATOR receiver
EGM95_RS03100	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EGM95_RS03115	COG0584	glycerophosphoryl diester phosphodiesterase
EGM95_RS03120	COG2096	Adenosyltransferase
EGM95_RS03125	COG4206	TonB-dependent receptor
EGM95_RS03180	COG0285	dihydrofolate synthase activity
EGM95_RS03200	COG0450	alkyl hydroperoxide reductase
EGM95_RS03215	COG0477	Major facilitator Superfamily
EGM95_RS03220	COG1272	protein, Hemolysin III
EGM95_RS03250	COG0183	Belongs to the thiolase family
EGM95_RS03255	COG2207	Transcriptional regulator
EGM95_RS03275	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGM95_RS03295	COG0183	Belongs to the thiolase family
EGM95_RS03305	COG2885	chlorophyll binding
EGM95_RS03305	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EGM95_RS03315	COG1690	Belongs to the RtcB family
EGM95_RS03320	COG0833	amino acid
EGM95_RS03330	COG2233	PERMEase
EGM95_RS03335	COG1217	gtp-binding protein TYPA
EGM95_RS03360	COG2094	Belongs to the DNA glycosylase MPG family
EGM95_RS03365	COG4772	TonB-dependent receptor
EGM95_RS03370	COG1902	pentaerythritol trinitrate reductase activity
EGM95_RS03375	COG0679	Auxin Efflux Carrier
EGM95_RS03385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGM95_RS03390	COG0354	folic acid binding
EGM95_RS03400	COG3189	MarR family transcriptional regulator
EGM95_RS03405	COG2824	Alkylphosphonate utilization operon protein PhnA
EGM95_RS03410	COG3422	double-strand break repair
EGM95_RS03450	COG0840	transmembrane signaling receptor activity
EGM95_RS03470	COG5510	response to toxic substance
EGM95_RS03480	COG2832	Protein of unknown function (DUF454)
EGM95_RS03485	COG1376	ErfK ybiS ycfS ynhG family protein
EGM95_RS03525	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EGM95_RS03535	COG1289	transmembrane transporter activity
EGM95_RS03540	COG2814	Major facilitator Superfamily
EGM95_RS03560	COG1115	amino acid carrier protein
EGM95_RS03565	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGM95_RS03570	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGM95_RS03575	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EGM95_RS03580	COG3590	peptidase
EGM95_RS03605	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGM95_RS03615	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EGM95_RS03620	COG1077	Cell shape determining protein MreB Mrl
EGM95_RS03625	COG1792	Involved in formation and maintenance of cell shape
EGM95_RS03630	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EGM95_RS03635	COG0424	maF-like protein
EGM95_RS03640	COG1530	ribonuclease E activity
EGM95_RS03650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM95_RS03660	COG0560	Phosphoserine phosphatase
EGM95_RS03670	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGM95_RS03695	COG2207	Transcriptional regulator
EGM95_RS03715	COG1113	amino acid transport
EGM95_RS03720	COG2828	Protein conserved in bacteria
EGM95_RS03725	COG0142	geranyltranstransferase activity
EGM95_RS03730	COG2315	Protein conserved in bacteria
EGM95_RS03745	COG1752	Esterase of the alpha-beta hydrolase superfamily
EGM95_RS03765	COG2194	sulfuric ester hydrolase activity
EGM95_RS03770	COG0745	RESPONSE REGULATOR receiver
EGM95_RS03775	COG0642	Histidine kinase
EGM95_RS03785	COG0004	ammonium transporteR
EGM95_RS03795	COG0583	DNA-binding transcription factor activity
EGM95_RS03815	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS03825	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS03835	COG0525	valine-tRNA ligase activity
EGM95_RS03845	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS03855	COG0393	Putative heavy-metal-binding
EGM95_RS03860	COG0393	Putative heavy-metal-binding
EGM95_RS03865	COG1538	Outer membrane efflux protein
EGM95_RS03875	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM95_RS03880	COG0671	phosphoesterase, PA-phosphatase related
EGM95_RS03885	COG0215	cysteine-tRNA ligase activity
EGM95_RS03910	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EGM95_RS03925	COG1648	precorrin-2 dehydrogenase activity
EGM95_RS03925	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EGM95_RS03930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EGM95_RS03935	COG1733	regulation of RNA biosynthetic process
EGM95_RS03945	COG0531	amino acid
EGM95_RS03960	COG0321	lipoyl(octanoyl) transferase activity
EGM95_RS03965	COG2921	Belongs to the UPF0250 family
EGM95_RS04005	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EGM95_RS04010	COG1053	succinate dehydrogenase
EGM95_RS04015	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EGM95_RS04040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGM95_RS04060	COG2354	Protein conserved in bacteria
EGM95_RS04065	COG2321	neutral zinc metallopeptidase
EGM95_RS04075	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS04085	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS04100	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS04110	COG2843	Capsule synthesis protein
EGM95_RS04125	COG0589	response to stress
EGM95_RS04145	COG0505	Belongs to the CarA family
EGM95_RS04170	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGM95_RS04175	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EGM95_RS04225	COG0477	Major facilitator Superfamily
EGM95_RS04230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EGM95_RS04245	COG1597	lipid kinase activity
EGM95_RS04250	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGM95_RS04280	COG0584	glycerophosphoryl diester phosphodiesterase
EGM95_RS04300	COG0741	lytic transglycosylase activity
EGM95_RS04325	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EGM95_RS04340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM95_RS04350	COG3811	Belongs to the UPF0386 family
EGM95_RS04400	COG0778	Nitroreductase
EGM95_RS04415	COG1929	Belongs to the glycerate kinase type-1 family
EGM95_RS04425	COG0243	molybdopterin cofactor binding
EGM95_RS04430	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EGM95_RS04435	COG3339	Conserved Protein
EGM95_RS04445	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EGM95_RS04460	COG1113	amino acid transport
EGM95_RS04470	COG0019	diaminopimelate decarboxylase activity
EGM95_RS04480	COG1280	lysine exporter protein (LysE YggA)
EGM95_RS04485	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EGM95_RS04515	COG0463	Glycosyl transferase, family 2
EGM95_RS04535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM95_RS04565	COG4591	ABC-type transport system involved in lipoprotein release permease component
EGM95_RS04570	COG1136	(ABC) transporter
EGM95_RS04575	COG2333	competence protein COMEC
EGM95_RS04575	COG0658	competence protein
EGM95_RS04585	COG0616	signal peptide processing
EGM95_RS04585	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EGM95_RS04590	COG0596	Alpha beta hydrolase
EGM95_RS04595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EGM95_RS04605	COG0628	permease
EGM95_RS04640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGM95_RS04660	COG0823	Involved in the tonB-independent uptake of proteins
EGM95_RS04680	COG0824	Thioesterase
EGM95_RS04685	COG1473	amidohydrolase
EGM95_RS04705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EGM95_RS04705	COG0047	phosphoribosylformylglycinamidine synthase activity
EGM95_RS04710	COG2814	Major facilitator Superfamily
EGM95_RS04725	COG1024	Enoyl-CoA hydratase
EGM95_RS04730	COG1056	cytidyltransferase-related domain
EGM95_RS04730	COG1051	belongs to the nudix hydrolase family
EGM95_RS04740	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EGM95_RS04755	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EGM95_RS04770	COG4625	pathogenesis
EGM95_RS04775	COG0583	DNA-binding transcription factor activity
EGM95_RS04780	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EGM95_RS04785	COG4208	sulfate ABC transporter
EGM95_RS04790	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EGM95_RS04800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EGM95_RS04805	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS04810	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EGM95_RS04815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EGM95_RS04835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGM95_RS04850	COG0681	Belongs to the peptidase S26 family
EGM95_RS04865	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EGM95_RS04875	COG1381	Involved in DNA repair and RecF pathway recombination
EGM95_RS04880	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EGM95_RS04890	COG4221	oxidoreductase activity
EGM95_RS04920	COG0436	Aminotransferase
EGM95_RS04940	COG0556	nucleotide-excision repair
EGM95_RS04995	COG2070	2-Nitropropane dioxygenase
EGM95_RS05025	COG1215	transferase activity, transferring glycosyl groups
EGM95_RS05040	COG0415	Belongs to the DNA photolyase family
EGM95_RS05050	COG1252	NADH dehydrogenase
EGM95_RS05055	COG1686	Belongs to the peptidase S11 family
EGM95_RS05070	COG1187	pseudouridine synthase activity
EGM95_RS05095	COG0477	Major facilitator Superfamily
EGM95_RS05100	COG0583	DNA-binding transcription factor activity
EGM95_RS05105	COG1823	symporter activity
EGM95_RS05115	COG0612	Peptidase, M16
EGM95_RS05140	COG0352	thiamine-phosphate diphosphorylase activity
EGM95_RS05175	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGM95_RS05190	COG1309	transcriptional regulator
EGM95_RS05200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EGM95_RS05205	COG0076	glutamate decarboxylase activity
EGM95_RS05215	COG1522	sequence-specific DNA binding
EGM95_RS05220	COG3961	Belongs to the TPP enzyme family
EGM95_RS05225	COG1113	amino acid transport
EGM95_RS05230	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EGM95_RS05235	COG0573	inorganic phosphate transmembrane transporter activity
EGM95_RS05245	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EGM95_RS05250	COG0616	signal peptide processing
EGM95_RS05290	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EGM95_RS05295	COG1686	Belongs to the peptidase S11 family
EGM95_RS05320	COG0583	DNA-binding transcription factor activity
EGM95_RS05325	COG1067	ATP-dependent peptidase activity
EGM95_RS05330	COG2211	Major facilitator Superfamily
EGM95_RS05350	COG4943	cyclic-guanylate-specific phosphodiesterase activity
EGM95_RS05370	COG1966	Carbon starvation protein
EGM95_RS05375	COG2879	small protein
EGM95_RS05400	COG1741	Belongs to the pirin family
EGM95_RS05410	COG2964	Protein conserved in bacteria
EGM95_RS05425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM95_RS05430	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM95_RS05435	COG4605	iron ion homeostasis
EGM95_RS05440	COG4604	ABC transporter, ATP-binding protein
EGM95_RS05445	COG4607	ABC-type enterochelin transport system periplasmic component
EGM95_RS05450	COG4774	siderophore transport
EGM95_RS05460	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EGM95_RS05465	COG1021	2,3-dihydroxybenzoate-AMP ligase
EGM95_RS05470	COG3433	isochorismatase activity
EGM95_RS05470	COG1535	isochorismatase
EGM95_RS05485	COG1132	(ABC) transporter
EGM95_RS05490	COG1132	(ABC) transporter
EGM95_RS05495	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EGM95_RS05505	COG1169	isochorismate synthase
EGM95_RS05520	COG3739	integral membrane protein
EGM95_RS05545	COG0302	gtp cyclohydrolase
EGM95_RS05555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EGM95_RS05590	COG0512	Glutamine amidotransferase of anthranilate synthase
EGM95_RS05860	COG1598	PFAM Uncharacterised protein family UPF0150
EGM95_RS05875	COG0739	heme binding
EGM95_RS05875	COG0741	lytic transglycosylase activity
EGM95_RS05875	COG1196	nuclear chromosome segregation
EGM95_RS05965	COG0582	viral genome integration into host DNA
EGM95_RS05980	COG0174	glutamine synthetase
EGM95_RS05990	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EGM95_RS06025	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EGM95_RS06030	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EGM95_RS06035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EGM95_RS06055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EGM95_RS06060	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EGM95_RS06065	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EGM95_RS06080	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS06085	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGM95_RS06090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGM95_RS06100	COG2223	nitrite transmembrane transporter activity
EGM95_RS06110	COG0024	Methionine aminopeptidase
EGM95_RS06115	COG0052	Belongs to the universal ribosomal protein uS2 family
EGM95_RS06130	COG2207	Transcriptional regulator
EGM95_RS06155	COG2951	lytic endotransglycosylase activity
EGM95_RS06160	COG0772	Belongs to the SEDS family
EGM95_RS06175	COG0842	Transport permease protein
EGM95_RS06180	COG1131	(ABC) transporter
EGM95_RS06185	COG0582	viral genome integration into host DNA
EGM95_RS06190	COG3617	BRO family, N-terminal domain
EGM95_RS06290	COG0305	Participates in initiation and elongation during chromosome replication
EGM95_RS06505	COG3561	AntA/AntB antirepressor
EGM95_RS06515	COG1196	nuclear chromosome segregation
EGM95_RS06515	COG0741	lytic transglycosylase activity
EGM95_RS06515	COG0739	heme binding
EGM95_RS06615	COG4215	(ABC) transporter
EGM95_RS06620	COG4160	amino acid transport
EGM95_RS06625	COG4598	ABC transporter
EGM95_RS06635	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM95_RS06640	COG0826	peptidase U32
EGM95_RS06645	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGM95_RS06660	COG1720	tRNA m6t6A37 methyltransferase activity
EGM95_RS06670	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EGM95_RS06685	COG0642	Histidine kinase
EGM95_RS06695	COG0494	nUDIX hydrolase
EGM95_RS06705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EGM95_RS06710	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EGM95_RS06715	COG3139	Protein of unknown function (DUF1315)
EGM95_RS06720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EGM95_RS06730	COG1301	dicarboxylic acid transport
EGM95_RS06735	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS06740	COG2819	hydrolase of the alpha beta superfamily
EGM95_RS06750	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EGM95_RS06760	COG2195	Cleaves the N-terminal amino acid of tripeptides
EGM95_RS06765	COG1234	tRNA 3'-trailer cleavage
EGM95_RS06795	COG2363	Small membrane protein
EGM95_RS06815	COG0513	Belongs to the DEAD box helicase family
EGM95_RS06825	COG0778	Nitroreductase
EGM95_RS06855	COG1286	toxin biosynthetic process
EGM95_RS06885	COG1610	YqeY-like protein
EGM95_RS06940	COG2831	hemolysin activation secretion protein
EGM95_RS07025	COG3111	PFAM Bacterial OB fold (BOF) protein
EGM95_RS07050	COG3243	poly(R)-hydroxyalkanoic acid synthase
EGM95_RS07055	COG0786	glutamate:sodium symporter activity
EGM95_RS07065	COG2186	Transcriptional regulator
EGM95_RS07115	COG0477	Major facilitator Superfamily
EGM95_RS07140	COG2985	domain, Protein
EGM95_RS07150	COG2995	paraquat-inducible protein a
EGM95_RS07155	COG3008	intermembrane lipid transfer
EGM95_RS07155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EGM95_RS07165	COG1794	racemase activity, acting on amino acids and derivatives
EGM95_RS07195	COG1301	dicarboxylic acid transport
EGM95_RS07205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGM95_RS07210	COG2011	ABC-type metal ion transport system permease component
EGM95_RS07215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGM95_RS07220	COG1464	Belongs to the NlpA lipoprotein family
EGM95_RS07225	COG0151	Belongs to the GarS family
EGM95_RS07230	COG0138	bifunctional purine biosynthesis protein purh
EGM95_RS07235	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EGM95_RS07265	COG2308	Evidence 4 Homologs of previously reported genes of
EGM95_RS07275	COG1305	Transglutaminase-like
EGM95_RS07285	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EGM95_RS07290	COG0305	Participates in initiation and elongation during chromosome replication
EGM95_RS07315	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EGM95_RS07325	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EGM95_RS07330	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EGM95_RS07355	COG0726	polysaccharide deacetylase
EGM95_RS07355	COG1649	PFAM Uncharacterised BCR, COG1649
EGM95_RS07360	COG1215	transferase activity, transferring glycosyl groups
EGM95_RS07365	COG3658	cytochrome
EGM95_RS07375	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM95_RS07395	COG0583	DNA-binding transcription factor activity
EGM95_RS07425	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS07430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGM95_RS07435	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGM95_RS07460	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EGM95_RS07465	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EGM95_RS07475	COG2205	protein histidine kinase activity
EGM95_RS07480	COG0745	RESPONSE REGULATOR receiver
EGM95_RS07485	COG0174	glutamine synthetase
EGM95_RS07505	COG0729	surface antigen
EGM95_RS07535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGM95_RS07540	COG2814	Major facilitator Superfamily
EGM95_RS07635	COG4397	Mu-like prophage major head subunit gpT
EGM95_RS07650	COG5005	Phage virion morphogenesis
EGM95_RS07655	COG2369	cell adhesion
EGM95_RS07660	COG4383	Mu-like prophage protein gp29
EGM95_RS07675	COG4373	Mu-like prophage FluMu protein gp28
EGM95_RS07710	COG0681	Belongs to the peptidase S26 family
EGM95_RS07735	COG3267	Type II secretory pathway component ExeA
EGM95_RS07735	COG3409	Peptidoglycan-binding domain 1 protein
EGM95_RS07765	COG0776	regulation of translation
EGM95_RS07815	COG0583	DNA-binding transcription factor activity
EGM95_RS07830	COG1187	pseudouridine synthase activity
EGM95_RS07850	COG0802	atpase or kinase
EGM95_RS07855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EGM95_RS07865	COG1923	regulation of RNA biosynthetic process
EGM95_RS07870	COG0697	spore germination
EGM95_RS07895	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGM95_RS07900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGM95_RS07900	COG0519	Catalyzes the synthesis of GMP from XMP
EGM95_RS07905	COG4302	ethanolamine ammonia-lyase activity
EGM95_RS07910	COG4303	Ethanolamine ammonia lyase large subunit
EGM95_RS07915	COG0531	amino acid
EGM95_RS07935	COG1454	alcohol dehydrogenase
EGM95_RS07940	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGM95_RS07965	COG0308	aminopeptidase N
EGM95_RS07985	COG1605	Chorismate mutase
EGM95_RS08115	COG0668	transmembrane transport
EGM95_RS08145	COG4773	Receptor
EGM95_RS08165	COG0488	(ABC) transporter
EGM95_RS08170	COG0589	response to stress
EGM95_RS08185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EGM95_RS08210	COG1522	sequence-specific DNA binding
EGM95_RS08220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EGM95_RS08225	COG0583	DNA-binding transcription factor activity
EGM95_RS08235	COG0183	Belongs to the thiolase family
EGM95_RS08245	COG2030	dehydratase
EGM95_RS08250	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGM95_RS08265	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EGM95_RS08275	COG0824	Thioesterase
EGM95_RS08280	COG1454	alcohol dehydrogenase
EGM95_RS08290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EGM95_RS08310	COG0069	glutamate synthase activity
EGM95_RS08330	COG2814	Major facilitator Superfamily
EGM95_RS08345	COG0511	ligase activity, forming carbon-carbon bonds
EGM95_RS08360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGM95_RS08360	COG1116	anion transmembrane transporter activity
EGM95_RS08365	COG0745	RESPONSE REGULATOR receiver
EGM95_RS08375	COG2146	nitrite reductase [NAD(P)H] activity
EGM95_RS08375	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGM95_RS08380	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGM95_RS08385	COG0243	molybdopterin cofactor binding
EGM95_RS08395	COG0243	molybdopterin cofactor binding
EGM95_RS08400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EGM95_RS08415	COG0315	cyclic pyranopterin monophosphate synthase activity
EGM95_RS08415	COG0521	Mo-molybdopterin cofactor biosynthetic process
EGM95_RS08420	COG0303	'Molybdopterin
EGM95_RS08430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGM95_RS08435	COG0697	spore germination
EGM95_RS08455	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EGM95_RS08460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGM95_RS08520	COG2204	response regulator
EGM95_RS08525	COG3852	Histidine kinase
EGM95_RS08550	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EGM95_RS08555	COG0575	Belongs to the CDS family
EGM95_RS08590	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGM95_RS08605	COG2137	regulation of response to DNA damage stimulus
EGM95_RS08615	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EGM95_RS08620	COG1011	Hydrolase
EGM95_RS08665	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM95_RS08735	COG1484	DNA-dependent DNA replication
EGM95_RS08980	COG2026	Addiction module toxin, RelE StbE family
EGM95_RS09020	COG0592	DNA-directed DNA polymerase activity
EGM95_RS09055	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS09105	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGM95_RS09150	COG1522	sequence-specific DNA binding
EGM95_RS09160	COG1113	amino acid transport
EGM95_RS09175	COG0659	secondary active sulfate transmembrane transporter activity
EGM95_RS09180	COG2135	peptidase activity
EGM95_RS09195	COG5001	Diguanylate cyclase
EGM95_RS09195	COG3300	MHYT domain
EGM95_RS09215	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM95_RS09215	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EGM95_RS09215	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EGM95_RS09220	COG1105	Belongs to the carbohydrate kinase PfkB family
EGM95_RS09225	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM95_RS09225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EGM95_RS09255	COG0024	Methionine aminopeptidase
EGM95_RS09260	COG0583	DNA-binding transcription factor activity
EGM95_RS09270	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EGM95_RS09275	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EGM95_RS09280	COG0517	IMP dehydrogenase activity
EGM95_RS09280	COG0516	GMP reductase activity
EGM95_RS09305	COG0552	protein localization to endoplasmic reticulum
EGM95_RS09315	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EGM95_RS09330	COG4890	Cyd operon protein YbgT
EGM95_RS09335	COG1294	oxidase, subunit
EGM95_RS09445	COG1585	Membrane protein implicated in regulation of membrane protease activity
EGM95_RS09455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EGM95_RS09460	COG4774	siderophore transport
EGM95_RS09475	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EGM95_RS09480	COG0569	domain protein
EGM95_RS09485	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EGM95_RS09515	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EGM95_RS09520	COG0542	response to heat
EGM95_RS09545	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGM95_RS09545	COG1902	pentaerythritol trinitrate reductase activity
EGM95_RS09605	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EGM95_RS09615	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGM95_RS09620	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EGM95_RS09625	COG0183	Belongs to the thiolase family
EGM95_RS09630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EGM95_RS09635	COG0596	Alpha beta hydrolase
EGM95_RS09640	COG2271	Major facilitator Superfamily
EGM95_RS09645	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGM95_RS09650	COG3485	protocatechuate 3,4-dioxygenase
EGM95_RS09655	COG3485	protocatechuate 3,4-dioxygenase
EGM95_RS09660	COG0710	3-dehydroquinate dehydratase activity
EGM95_RS09665	COG3420	alginic acid biosynthetic process
EGM95_RS09670	COG3659	wide pore channel activity
EGM95_RS09675	COG4993	Dehydrogenase
EGM95_RS09685	COG2391	methyltransferase activity
EGM95_RS09700	COG1414	Transcriptional regulator
EGM95_RS09705	COG0583	DNA-binding transcription factor activity
EGM95_RS09710	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS09735	COG2814	Major facilitator Superfamily
EGM95_RS09745	COG0154	amidase activity
EGM95_RS09765	COG4638	Rieske (2fe-2S)
EGM95_RS09775	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS09785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGM95_RS09795	COG3733	amine oxidase
EGM95_RS09805	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS09810	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGM95_RS09815	COG0183	Belongs to the thiolase family
EGM95_RS09820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EGM95_RS09825	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGM95_RS09835	COG4829	muconolactone delta-isomerase
EGM95_RS09840	COG4948	Mandelate Racemase Muconate Lactonizing
EGM95_RS09845	COG0583	DNA-binding transcription factor activity
EGM95_RS09855	COG2186	Transcriptional regulator
EGM95_RS09875	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS09880	COG3231	kanamycin kinase activity
EGM95_RS09895	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS09900	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS09905	COG3829	transcription factor binding
EGM95_RS09920	COG3162	membrane
EGM95_RS09935	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS09950	COG0753	catalase activity
EGM95_RS09975	COG1846	Transcriptional regulator
EGM95_RS09980	COG1902	pentaerythritol trinitrate reductase activity
EGM95_RS09980	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGM95_RS09990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EGM95_RS10020	COG1309	transcriptional regulator
EGM95_RS10030	COG1335	isochorismatase
EGM95_RS10035	COG0583	DNA-binding transcription factor activity
EGM95_RS10045	COG0475	glutathione-regulated potassium exporter activity
EGM95_RS10045	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGM95_RS10055	COG1473	amidohydrolase
EGM95_RS10075	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS10120	COG2188	Transcriptional regulator
EGM95_RS10135	COG0583	DNA-binding transcription factor activity
EGM95_RS10155	COG2831	hemolysin activation secretion protein
EGM95_RS10160	COG3210	domain, Protein
EGM95_RS10180	COG1566	PFAM secretion protein HlyD family protein
EGM95_RS10210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGM95_RS10220	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS10240	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGM95_RS10260	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS10275	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EGM95_RS10280	COG2814	Major facilitator Superfamily
EGM95_RS10290	COG0179	Fumarylacetoacetate (FAA) hydrolase
EGM95_RS10300	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS10305	COG3384	dioxygenase
EGM95_RS10315	COG3971	2-oxopent-4-enoate hydratase activity
EGM95_RS10330	COG0477	Major facilitator Superfamily
EGM95_RS10335	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS10340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGM95_RS10345	COG1846	Transcriptional regulator
EGM95_RS10350	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS10355	COG0129	dihydroxy-acid dehydratase activity
EGM95_RS10365	COG0583	DNA-binding transcription factor activity
EGM95_RS10370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EGM95_RS10380	COG2084	Dehydrogenase
EGM95_RS10385	COG2207	Transcriptional regulator
EGM95_RS10395	COG1064	alcohol dehydrogenase
EGM95_RS10405	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EGM95_RS10410	COG1120	ATPase activity
EGM95_RS10430	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGM95_RS10480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EGM95_RS10490	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS10515	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS10555	COG1073	alpha beta
EGM95_RS10565	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS10575	COG2207	Transcriptional regulator
EGM95_RS10585	COG2205	protein histidine kinase activity
EGM95_RS10590	COG0745	RESPONSE REGULATOR receiver
EGM95_RS10595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM95_RS10600	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGM95_RS10615	COG2072	flavoprotein involved in K transport
EGM95_RS10635	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGM95_RS10650	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS10655	COG3938	Belongs to the proline racemase family
EGM95_RS10670	COG2267	carboxylic ester hydrolase activity
EGM95_RS10675	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
EGM95_RS10680	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS10685	COG4580	involved in the transport of maltose and maltodextrins
EGM95_RS10700	COG2223	nitrite transmembrane transporter activity
EGM95_RS10710	COG0697	spore germination
EGM95_RS10720	COG1609	Transcriptional regulator
EGM95_RS10725	COG1346	cytolysis
EGM95_RS10735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGM95_RS10740	COG0028	Belongs to the TPP enzyme family
EGM95_RS10755	COG0483	inositol monophosphate 1-phosphatase activity
EGM95_RS10770	COG4580	involved in the transport of maltose and maltodextrins
EGM95_RS10780	COG0028	Belongs to the TPP enzyme family
EGM95_RS10790	COG1609	Transcriptional regulator
EGM95_RS10810	COG0494	nUDIX hydrolase
EGM95_RS10815	COG0656	L-ascorbic acid biosynthetic process
EGM95_RS10945	COG3539	Fimbrial protein
EGM95_RS10970	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EGM95_RS10980	COG0753	catalase activity
EGM95_RS10995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EGM95_RS11060	COG1535	isochorismatase
EGM95_RS11060	COG3433	isochorismatase activity
EGM95_RS11065	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS11070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EGM95_RS11075	COG4149	molybdate abc transporter
EGM95_RS11080	COG0725	ABC transporter, periplasmic molybdate-binding protein
EGM95_RS11090	COG4638	Rieske (2fe-2S)
EGM95_RS11095	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EGM95_RS11100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGM95_RS11100	COG0543	2 iron, 2 sulfur cluster binding
EGM95_RS11115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGM95_RS11125	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS11140	COG2207	Transcriptional regulator
EGM95_RS11145	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS11150	COG2610	gluconate transmembrane transporter activity
EGM95_RS11160	COG1309	transcriptional regulator
EGM95_RS11180	COG0583	DNA-binding transcription factor activity
EGM95_RS11195	COG2031	fatty acid transporter
EGM95_RS11200	COG0183	Belongs to the thiolase family
EGM95_RS11205	COG0583	DNA-binding transcription factor activity
EGM95_RS11210	COG0583	DNA-binding transcription factor activity
EGM95_RS11225	COG1027	Aspartate ammonia-lyase
EGM95_RS11235	COG0477	Major facilitator Superfamily
EGM95_RS11255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGM95_RS11260	COG4521	taurine ABC transporter
EGM95_RS11275	COG2188	Transcriptional regulator
EGM95_RS11285	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGM95_RS11290	COG1733	regulation of RNA biosynthetic process
EGM95_RS11295	COG2207	Transcriptional regulator
EGM95_RS11295	COG3708	Transcriptional regulator
EGM95_RS11310	COG0730	response to heat
EGM95_RS11320	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGM95_RS11320	COG3453	Protein conserved in bacteria
EGM95_RS11330	COG3781	membrane
EGM95_RS11335	COG1063	alcohol dehydrogenase
EGM95_RS11345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EGM95_RS11350	COG0508	dehydrogenase complex catalyzes the overall conversion of
EGM95_RS11355	COG0022	dehydrogenase e1 component
EGM95_RS11360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EGM95_RS11365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EGM95_RS11380	COG3706	GGDEF domain
EGM95_RS11395	COG0133	tryptophan synthase activity
EGM95_RS11405	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EGM95_RS11440	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EGM95_RS11525	COG0842	Transport permease protein
EGM95_RS11540	COG1131	(ABC) transporter
EGM95_RS11555	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EGM95_RS11560	COG4773	Receptor
EGM95_RS11580	COG0730	response to heat
EGM95_RS11585	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EGM95_RS11600	COG0406	alpha-ribazole phosphatase activity
EGM95_RS11605	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EGM95_RS11650	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGM95_RS11660	COG4264	IucA IucC family
EGM95_RS11665	COG4264	IucA IucC family
EGM95_RS11670	COG2814	Major facilitator Superfamily
EGM95_RS11685	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EGM95_RS11700	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS11705	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS11710	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EGM95_RS11715	COG2207	Transcriptional regulator
EGM95_RS11720	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGM95_RS11725	COG0776	regulation of translation
EGM95_RS11750	COG0822	iron-sulfur transferase activity
EGM95_RS11755	COG0316	Belongs to the HesB IscA family
EGM95_RS11785	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EGM95_RS11805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EGM95_RS11810	COG0702	epimerase
EGM95_RS11845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EGM95_RS11855	COG0339	signal peptide processing
EGM95_RS11905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EGM95_RS11910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EGM95_RS11925	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS11955	COG0776	regulation of translation
EGM95_RS12020	COG0084	hydrolase, TatD family'
EGM95_RS12040	COG1663	tetraacyldisaccharide 4'-kinase activity
EGM95_RS12045	COG1132	(ABC) transporter
EGM95_RS12055	COG0811	peptide transport
EGM95_RS12060	COG1475	DNA binding
EGM95_RS12065	COG1192	Involved in chromosome partitioning
EGM95_RS12075	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EGM95_RS12090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EGM95_RS12095	COG0191	fructose-bisphosphate aldolase activity
EGM95_RS12115	COG0424	maF-like protein
EGM95_RS12120	COG2850	peptidyl-arginine hydroxylation
EGM95_RS12130	COG0640	Transcriptional regulator
EGM95_RS12140	COG3619	membrane
EGM95_RS12145	COG3122	Protein conserved in bacteria
EGM95_RS12150	COG1132	(ABC) transporter
EGM95_RS12170	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EGM95_RS12175	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EGM95_RS12185	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGM95_RS12185	COG0506	proline dehydrogenase activity
EGM95_RS12185	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EGM95_RS12190	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EGM95_RS12205	COG3698	Phosphodiester glycosidase
EGM95_RS12215	COG2353	YceI-like domain
EGM95_RS12225	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EGM95_RS12270	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EGM95_RS12270	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EGM95_RS12295	COG3539	Fimbrial protein
EGM95_RS12300	COG3121	Chaperone
EGM95_RS12330	COG0697	spore germination
EGM95_RS12340	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EGM95_RS12350	COG0583	DNA-binding transcription factor activity
EGM95_RS12370	COG1309	transcriptional regulator
EGM95_RS12385	COG1522	sequence-specific DNA binding
EGM95_RS12395	COG1126	abc transporter atp-binding protein
EGM95_RS12400	COG0765	amino acid transport
EGM95_RS12405	COG0765	amino acid transport
EGM95_RS12435	COG1464	Belongs to the NlpA lipoprotein family
EGM95_RS12445	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EGM95_RS12450	COG2011	ABC-type metal ion transport system permease component
EGM95_RS12455	COG0012	GTP binding
EGM95_RS12480	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EGM95_RS12505	COG0436	Aminotransferase
EGM95_RS12520	COG0386	Belongs to the glutathione peroxidase family
EGM95_RS12530	COG0436	Aminotransferase
EGM95_RS12535	COG1301	dicarboxylic acid transport
EGM95_RS12570	COG3634	alkyl hydroperoxide reductase activity
EGM95_RS12585	COG0583	DNA-binding transcription factor activity
EGM95_RS12590	COG0798	PFAM Bile acid sodium symporter
EGM95_RS12595	COG0640	Transcriptional regulator
EGM95_RS12610	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EGM95_RS12620	COG0583	DNA-binding transcription factor activity
EGM95_RS12630	COG1953	Uracil, thiamine, allantoin
EGM95_RS12640	COG2175	clavaminate synthase activity
EGM95_RS12645	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGM95_RS12655	COG4521	taurine ABC transporter
EGM95_RS12670	COG0477	Major facilitator Superfamily
EGM95_RS12695	COG1271	oxidase subunit
EGM95_RS12700	COG1294	oxidase, subunit
EGM95_RS12710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGM95_RS12730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EGM95_RS12750	COG3052	prosthetic group binding
EGM95_RS12755	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EGM95_RS12765	COG0583	DNA-binding transcription factor activity
EGM95_RS12775	COG2814	Major facilitator Superfamily
EGM95_RS12795	COG1346	cytolysis
EGM95_RS12805	COG0583	DNA-binding transcription factor activity
EGM95_RS12810	COG0625	glutathione transferase activity
EGM95_RS12815	COG0625	glutathione transferase activity
EGM95_RS12820	COG0583	DNA-binding transcription factor activity
EGM95_RS12835	COG1045	serine acetyltransferase
EGM95_RS12840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EGM95_RS12845	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EGM95_RS12855	COG1280	lysine exporter protein (LysE YggA)
EGM95_RS12870	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM95_RS12875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM95_RS12880	COG1126	abc transporter atp-binding protein
EGM95_RS12885	COG0765	amino acid transport
EGM95_RS12890	COG0765	amino acid transport
EGM95_RS12910	COG2205	protein histidine kinase activity
EGM95_RS12910	COG0784	Response regulator, receiver
EGM95_RS12930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EGM95_RS12950	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS12995	COG0583	DNA-binding transcription factor activity
EGM95_RS13015	COG0318	PFAM AMP-dependent synthetase and ligase
EGM95_RS13020	COG1309	transcriptional regulator
EGM95_RS13025	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS13030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EGM95_RS13035	COG1024	Enoyl-CoA hydratase
EGM95_RS13040	COG4770	biotin carboxylase activity
EGM95_RS13050	COG0583	DNA-binding transcription factor activity
EGM95_RS13065	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS13075	COG2814	Major facilitator Superfamily
EGM95_RS13085	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EGM95_RS13090	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EGM95_RS13095	COG2814	Major facilitator Superfamily
EGM95_RS13100	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS13105	COG1024	Enoyl-CoA hydratase
EGM95_RS13110	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS13115	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGM95_RS13120	COG0183	Belongs to the thiolase family
EGM95_RS13135	COG1280	lysine exporter protein (LysE YggA)
EGM95_RS13140	COG2192	nodulation
EGM95_RS13155	COG1024	Enoyl-CoA hydratase
EGM95_RS13170	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS13175	COG2814	Major facilitator Superfamily
EGM95_RS13180	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EGM95_RS13185	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EGM95_RS13200	COG3842	ATPase activity
EGM95_RS13205	COG1840	ABC-type Fe3 transport system, periplasmic component
EGM95_RS13215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM95_RS13220	COG1414	Transcriptional regulator
EGM95_RS13230	COG0583	DNA-binding transcription factor activity
EGM95_RS13235	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EGM95_RS13240	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS13250	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EGM95_RS13260	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS13265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM95_RS13270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGM95_RS13275	COG2267	carboxylic ester hydrolase activity
EGM95_RS13295	COG3038	cytochrome b561
EGM95_RS13300	COG0753	catalase activity
EGM95_RS13330	COG2050	protein possibly involved in aromatic compounds catabolism
EGM95_RS13340	COG3327	negative regulation of DNA-templated transcription, initiation
EGM95_RS13345	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EGM95_RS13350	COG0183	Belongs to the thiolase family
EGM95_RS13355	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGM95_RS13360	COG1024	Enoyl-CoA hydratase
EGM95_RS13365	COG1024	Enoyl-CoA hydratase
EGM95_RS13370	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EGM95_RS13375	COG2151	metal-sulfur cluster biosynthetic enzyme
EGM95_RS13380	COG3396	Phenylacetate-CoA oxygenase
EGM95_RS13385	COG3460	Phenylacetate-CoA oxygenase
EGM95_RS13390	COG3396	Phenylacetate-CoA oxygenase
EGM95_RS13395	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS13395	COG2030	dehydratase
EGM95_RS13400	COG1760	l-serine dehydratase
EGM95_RS13405	COG0531	amino acid
EGM95_RS13410	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS13435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EGM95_RS13455	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGM95_RS13470	COG0789	Transcriptional regulator
EGM95_RS13480	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EGM95_RS13495	COG2807	transmembrane transport
EGM95_RS13500	COG0590	tRNA wobble adenosine to inosine editing
EGM95_RS13600	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS13625	COG1116	anion transmembrane transporter activity
EGM95_RS13630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EGM95_RS13640	COG0864	Transcriptional regulator
EGM95_RS13650	COG1733	regulation of RNA biosynthetic process
EGM95_RS13655	COG2249	NAD(P)H dehydrogenase (quinone) activity
EGM95_RS13660	COG0439	Biotin carboxylase
EGM95_RS13675	COG1063	alcohol dehydrogenase
EGM95_RS13700	COG0038	chloride channel
EGM95_RS13705	COG4770	biotin carboxylase activity
EGM95_RS13725	COG1914	H( )-stimulated, divalent metal cation uptake system
EGM95_RS13730	COG0583	DNA-binding transcription factor activity
EGM95_RS13795	COG1250	3-hydroxyacyl-CoA dehydrogenase
EGM95_RS13820	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EGM95_RS13845	COG2814	Major facilitator Superfamily
EGM95_RS13860	COG1560	Kdo2-lipid A biosynthetic process
EGM95_RS13870	COG5006	permease, DMT superfamily
EGM95_RS13875	COG1522	sequence-specific DNA binding
EGM95_RS13890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EGM95_RS13900	COG4122	O-methyltransferase activity
EGM95_RS13930	COG1538	Outer membrane efflux protein
EGM95_RS13935	COG1137	ATPase activity
EGM95_RS13940	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EGM95_RS13950	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EGM95_RS13995	COG2814	Major facilitator Superfamily
EGM95_RS14030	COG1278	Cold shock
EGM95_RS14035	COG1280	lysine exporter protein (LysE YggA)
EGM95_RS14070	COG1570	exodeoxyribonuclease VII activity
EGM95_RS14155	COG2871	sodium ion transport
EGM95_RS14165	COG0583	DNA-binding transcription factor activity
EGM95_RS14170	COG4638	Rieske (2fe-2S)
EGM95_RS14175	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EGM95_RS14180	COG0633	Ferredoxin
EGM95_RS14180	COG0543	2 iron, 2 sulfur cluster binding
EGM95_RS14185	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS14190	COG3135	benzoate transporter
EGM95_RS14195	COG2814	Major facilitator Superfamily
EGM95_RS14210	COG1643	Atp-dependent helicase
EGM95_RS14215	COG0450	alkyl hydroperoxide reductase
EGM95_RS14225	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EGM95_RS14235	COG3634	alkyl hydroperoxide reductase activity
EGM95_RS14255	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EGM95_RS14260	COG0625	glutathione transferase activity
EGM95_RS14270	COG2885	chlorophyll binding
EGM95_RS14305	COG0542	response to heat
EGM95_RS14320	COG1765	OsmC-like protein
EGM95_RS14330	COG0667	Aldo Keto reductase
EGM95_RS14345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EGM95_RS14355	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EGM95_RS14365	COG0582	viral genome integration into host DNA
EGM95_RS14765	COG0527	aspartate kinase activity
EGM95_RS14775	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EGM95_RS14785	COG3038	cytochrome b561
EGM95_RS14790	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EGM95_RS14795	COG2252	PERMEase
EGM95_RS14805	COG2072	flavoprotein involved in K transport
EGM95_RS14820	COG1741	Belongs to the pirin family
EGM95_RS14825	COG1309	transcriptional regulator
EGM95_RS14835	COG0300	oxidoreductase activity
EGM95_RS14840	COG2072	flavoprotein involved in K transport
EGM95_RS14845	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
EGM95_RS14910	COG3209	COG3209 Rhs family protein
EGM95_RS14965	COG0446	pyridine nucleotide-disulphide oxidoreductase
EGM95_RS14965	COG1902	pentaerythritol trinitrate reductase activity
EGM95_RS14975	COG2203	Gaf domain
EGM95_RS14975	COG3706	GGDEF domain
EGM95_RS14975	COG4251	negative regulation of phosphorylation
EGM95_RS14975	COG5001	Diguanylate cyclase
EGM95_RS14985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM95_RS15005	COG4172	Belongs to the ABC transporter superfamily
EGM95_RS15010	COG4239	(ABC) transporter, permease
EGM95_RS15015	COG4174	ABC transporter (Permease)
EGM95_RS15025	COG0741	lytic transglycosylase activity
EGM95_RS15025	COG1388	LysM domain
EGM95_RS15025	COG0741	lytic transglycosylase activity
EGM95_RS15025	COG1388	LysM domain
EGM95_RS15030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EGM95_RS15070	COG0583	DNA-binding transcription factor activity
EGM95_RS15075	COG1279	arginine transmembrane transporter activity
EGM95_RS15095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM95_RS15100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EGM95_RS15105	COG0006	proline dipeptidase activity
EGM95_RS15135	COG2194	sulfuric ester hydrolase activity
EGM95_RS15200	COG0741	lytic transglycosylase activity
EGM95_RS15200	COG0739	heme binding
EGM95_RS15200	COG1196	nuclear chromosome segregation
EGM95_RS15535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EGM95_RS15560	COG3384	dioxygenase
EGM95_RS15570	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EGM95_RS15575	COG2878	Part of a membrane complex involved in electron transport
EGM95_RS15580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EGM95_RS15605	COG0768	penicillin binding
EGM95_RS15610	COG0742	ribosomal rna small subunit methyltransferase
EGM95_RS15625	COG0830	nickel cation binding
EGM95_RS15635	COG0804	urea catabolic process
EGM95_RS15680	COG1253	flavin adenine dinucleotide binding
EGM95_RS15690	COG2851	Citrate transporter
EGM95_RS15740	COG1773	rubredoxin
EGM95_RS15745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EGM95_RS15755	COG0583	DNA-binding transcription factor activity
EGM95_RS15790	COG4181	ATPase activity
EGM95_RS15835	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EGM95_RS15855	COG0306	phosphate transporter
EGM95_RS15865	COG3958	Transketolase
EGM95_RS15870	COG3959	Transketolase, thiamine diphosphate binding domain
EGM95_RS15875	COG2271	Major facilitator Superfamily
EGM95_RS15880	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS15885	COG0583	DNA-binding transcription factor activity
EGM95_RS15905	COG2223	nitrite transmembrane transporter activity
EGM95_RS15910	COG2207	Transcriptional regulator
EGM95_RS15915	COG2066	Belongs to the glutaminase family
EGM95_RS15920	COG0242	peptide deformylase activity
EGM95_RS15925	COG0477	Major facilitator Superfamily
EGM95_RS15935	COG0028	Belongs to the TPP enzyme family
EGM95_RS15950	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS15955	COG2267	carboxylic ester hydrolase activity
EGM95_RS15965	COG2271	Major facilitator Superfamily
EGM95_RS16000	COG1414	Transcriptional regulator
EGM95_RS16025	COG1215	transferase activity, transferring glycosyl groups
EGM95_RS16030	COG1649	PFAM Uncharacterised BCR, COG1649
EGM95_RS16030	COG0726	polysaccharide deacetylase
EGM95_RS16040	COG4681	YaeQ
EGM95_RS16050	COG0523	cobalamin synthesis protein
EGM95_RS16060	COG1607	acyl-coa hydrolase
EGM95_RS16070	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGM95_RS16075	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EGM95_RS16080	COG1309	transcriptional regulator
EGM95_RS16105	COG2040	homocysteine
EGM95_RS16110	COG0531	amino acid
EGM95_RS16165	COG1595	DNA-templated transcription, initiation
EGM95_RS16175	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGM95_RS16180	COG0477	Major facilitator Superfamily
EGM95_RS16210	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EGM95_RS16295	COG0582	viral genome integration into host DNA
EGM95_RS16305	COG0405	Gamma-glutamyltransferase
EGM95_RS16310	COG2814	Major facilitator Superfamily
EGM95_RS16320	COG2050	protein possibly involved in aromatic compounds catabolism
EGM95_RS16335	COG1090	epimerase
EGM95_RS16355	COG0420	3'-5' exonuclease activity
EGM95_RS16380	COG0735	belongs to the Fur family
EGM95_RS16385	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EGM95_RS16410	COG0121	glutamine amidotransferase
EGM95_RS16425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGM95_RS16435	COG0210	DNA helicase
EGM95_RS16440	COG2885	chlorophyll binding
EGM95_RS16445	COG0204	Acyl-transferase
EGM95_RS16460	COG2894	cell division
EGM95_RS16480	COG1280	lysine exporter protein (LysE YggA)
EGM95_RS16485	COG1674	ftsk spoiiie
EGM95_RS16485	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EGM95_RS16490	COG0492	ferredoxin-NADP+ reductase activity
EGM95_RS16495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EGM95_RS16505	COG0456	acetyltransferase
EGM95_RS16550	COG1981	membrane
EGM95_RS16565	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGM95_RS16565	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EGM95_RS16585	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS16595	COG0657	acetylesterase activity
EGM95_RS16605	COG0473	3-isopropylmalate dehydrogenase activity
EGM95_RS16610	COG0583	DNA-binding transcription factor activity
EGM95_RS16630	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM95_RS16655	COG0564	pseudouridine synthase activity
EGM95_RS16665	COG0358	DNA primase activity
EGM95_RS16680	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EGM95_RS16710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EGM95_RS16740	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EGM95_RS16750	COG0352	thiamine-phosphate diphosphorylase activity
EGM95_RS16750	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EGM95_RS16750	COG0351	phosphomethylpyrimidine kinase
EGM95_RS16755	COG1652	LysM domain
EGM95_RS16780	COG1399	metal-binding, possibly nucleic acid-binding protein
EGM95_RS16785	COG3101	peptidyl-lysine hydroxylation
EGM95_RS16790	COG0009	L-threonylcarbamoyladenylate synthase
EGM95_RS16795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EGM95_RS16800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EGM95_RS16815	COG4106	trans-aconitate 2-methyltransferase activity
EGM95_RS16830	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGM95_RS16830	COG0596	Alpha beta hydrolase
EGM95_RS16830	COG2226	methyltransferase
EGM95_RS16835	COG1877	trehalose-phosphatase activity
EGM95_RS16840	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EGM95_RS16845	COG2223	nitrite transmembrane transporter activity
EGM95_RS16865	COG1196	nuclear chromosome segregation
EGM95_RS16875	COG0730	response to heat
EGM95_RS16890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EGM95_RS16900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGM95_RS16960	COG0489	protein tyrosine kinase activity
EGM95_RS16970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGM95_RS16970	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGM95_RS17000	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EGM95_RS17005	COG2081	HI0933 family
EGM95_RS17015	COG0668	transmembrane transport
EGM95_RS17035	COG0583	DNA-binding transcription factor activity
EGM95_RS17055	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EGM95_RS17060	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGM95_RS17090	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EGM95_RS17130	COG0745	RESPONSE REGULATOR receiver
EGM95_RS17150	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EGM95_RS17160	COG0384	phenazine biosynthesis protein PhzF
EGM95_RS17220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EGM95_RS17250	COG0583	DNA-binding transcription factor activity
EGM95_RS17270	COG0583	DNA-binding transcription factor activity
EGM95_RS17285	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EGM95_RS17290	COG2814	Major facilitator Superfamily
EGM95_RS17295	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS17300	COG0583	DNA-binding transcription factor activity
EGM95_RS17305	COG1063	alcohol dehydrogenase
EGM95_RS17335	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EGM95_RS17340	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EGM95_RS17345	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGM95_RS17365	COG2132	Multicopper oxidase
EGM95_RS17375	COG0561	phosphatase activity
EGM95_RS17380	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EGM95_RS17390	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
EGM95_RS17405	COG1214	PFAM Peptidase M22, glycoprotease
EGM95_RS17465	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EGM95_RS17470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EGM95_RS17475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EGM95_RS17535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EGM95_RS17545	COG1846	Transcriptional regulator
EGM95_RS17550	COG1764	response to oxidative stress
EGM95_RS17590	COG0037	tRNA processing
EGM95_RS17600	COG0248	Ppx GppA phosphatase
EGM95_RS17630	COG0072	phenylalanine-tRNA ligase activity
EGM95_RS17665	COG1238	metal cluster binding
EGM95_RS17670	COG0625	glutathione transferase activity
EGM95_RS17690	COG0318	PFAM AMP-dependent synthetase and ligase
EGM95_RS17695	COG3028	Belongs to the UPF0307 family
EGM95_RS17700	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EGM95_RS17720	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EGM95_RS17725	COG0617	tRNA 3'-terminal CCA addition
EGM95_RS17730	COG1555	photosystem II stabilization
EGM95_RS17735	COG3956	TIGRFAM MazG family protein
EGM95_RS17745	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EGM95_RS17765	COG5002	protein histidine kinase activity
EGM95_RS17765	COG0784	Response regulator, receiver
EGM95_RS17765	COG2205	protein histidine kinase activity
EGM95_RS17770	COG1024	Enoyl-CoA hydratase
EGM95_RS17775	COG2084	Dehydrogenase
EGM95_RS17780	COG3622	Belongs to the hyi family
EGM95_RS17810	COG0697	spore germination
EGM95_RS17820	COG2814	Major facilitator Superfamily
EGM95_RS17825	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EGM95_RS17835	COG0583	DNA-binding transcription factor activity
EGM95_RS17845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EGM95_RS17860	COG0084	hydrolase, TatD family'
EGM95_RS17875	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EGM95_RS17910	COG0440	acetolactate synthase activity
EGM95_RS17915	COG0028	Belongs to the TPP enzyme family
EGM95_RS17945	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EGM95_RS17950	COG0577	efflux transmembrane transporter activity
EGM95_RS17950	COG1136	(ABC) transporter
EGM95_RS17955	COG1538	Outer membrane efflux protein
EGM95_RS17970	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EGM95_RS17975	COG1162	GTPase activity
EGM95_RS17985	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EGM95_RS18025	COG1426	Protein conserved in bacteria
EGM95_RS18060	COG0793	Belongs to the peptidase S41A family
EGM95_RS18075	COG2267	carboxylic ester hydrolase activity
EGM95_RS18085	COG1012	belongs to the aldehyde dehydrogenase family
EGM95_RS18090	COG3265	gluconokinase activity
EGM95_RS18100	COG0800	Aldolase
EGM95_RS18110	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EGM95_RS18115	COG0280	phosphate acetyltransferase
EGM95_RS18115	COG0857	belongs to the CobB CobQ family
EGM95_RS18120	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM95_RS18120	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EGM95_RS18140	COG0740	serine-type endopeptidase activity
EGM95_RS18150	COG4774	siderophore transport
EGM95_RS18160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EGM95_RS18170	COG2813	Specifically methylates the guanine in position
EGM95_RS18170	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EGM95_RS18270	COG0788	formyltetrahydrofolate deformylase activity
EGM95_RS18295	COG4651	solute:proton antiporter activity
EGM95_RS18295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGM95_RS18315	COG0724	RNA recognition motif
EGM95_RS18320	COG0210	DNA helicase
EGM95_RS18345	COG1733	regulation of RNA biosynthetic process
EGM95_RS18355	COG2900	Belongs to the SlyX family
EGM95_RS18360	COG0488	(ABC) transporter
EGM95_RS18365	COG1280	lysine exporter protein (LysE YggA)
EGM95_RS18370	COG1560	Kdo2-lipid A biosynthetic process
EGM95_RS18385	COG2826	transposase and inactivated derivatives, IS30 family
EGM95_RS18445	COG0473	3-isopropylmalate dehydrogenase activity
EGM95_RS18520	COG0625	glutathione transferase activity
EGM95_RS18525	COG2378	regulation of single-species biofilm formation
EGM95_RS18530	COG0546	phosphoglycolate phosphatase activity
EGM95_RS18545	COG1530	ribonuclease E activity
EGM95_RS18550	COG0318	PFAM AMP-dependent synthetase and ligase
EGM95_RS18565	COG0583	DNA-binding transcription factor activity
EGM95_RS18570	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS18575	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EGM95_RS18585	COG0534	Mate efflux family protein
EGM95_RS18600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGM95_RS18630	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
EGM95_RS18630	COG0493	'glutamate synthase
EGM95_RS18640	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EGM95_RS18645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EGM95_RS18660	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EGM95_RS18670	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EGM95_RS18670	COG0644	oxidoreductase
EGM95_RS18675	COG0425	Belongs to the sulfur carrier protein TusA family
EGM95_RS18680	COG4535	Mg2 and Co2 transporter CorC
EGM95_RS18690	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EGM95_RS18710	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EGM95_RS18715	COG0475	glutathione-regulated potassium exporter activity
EGM95_RS18715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EGM95_RS18730	COG0484	heat shock protein binding
EGM95_RS18735	COG0789	Transcriptional regulator
EGM95_RS18740	COG0598	Magnesium transport protein CorA
EGM95_RS18755	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EGM95_RS18760	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EGM95_RS18765	COG1074	ATP-dependent DNA helicase activity
EGM95_RS18770	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EGM95_RS18790	COG2226	methyltransferase
EGM95_RS18800	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EGM95_RS18810	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EGM95_RS18825	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EGM95_RS18825	COG2111	Na H antiporter
EGM95_RS18830	COG1006	Multisubunit Na H antiporter MnhC subunit
EGM95_RS18835	COG0651	ATP synthesis coupled electron transport
EGM95_RS18840	COG1863	multisubunit Na H antiporter MnhE subunit
EGM95_RS18845	COG2212	antiporter activity
EGM95_RS18850	COG1320	monovalent cation:proton antiporter activity
EGM95_RS18865	COG0195	Participates in both transcription termination and antitermination
EGM95_RS18915	COG0237	dephospho-CoA kinase activity
EGM95_RS18925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EGM95_RS18940	COG0497	DNA recombination
EGM95_RS18950	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EGM95_RS18980	COG2169	Transcriptional regulator
EGM95_RS18980	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EGM95_RS18985	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EGM95_RS19050	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EGM95_RS19065	COG0326	Molecular chaperone. Has ATPase activity
EGM95_RS19080	COG2056	Na+-H+ antiporter family
EGM95_RS19085	COG0596	Alpha beta hydrolase
EGM95_RS19180	COG0546	phosphoglycolate phosphatase activity
EGM95_RS19185	COG1716	ATPase activity
EGM95_RS19230	COG0181	hydroxymethylbilane synthase activity
EGM95_RS19240	COG3275	phosphorelay sensor kinase activity
EGM95_RS19260	COG1538	Outer membrane efflux protein
EGM95_RS19265	COG0697	spore germination
EGM95_RS19290	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EGM95_RS19295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EGM95_RS19300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EGM95_RS19305	COG0772	Belongs to the SEDS family
EGM95_RS19330	COG4974	Belongs to the 'phage' integrase family
EGM95_RS19335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGM95_RS19345	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EGM95_RS19355	COG2197	response regulator
EGM95_RS19380	COG0793	Belongs to the peptidase S41A family
EGM95_RS19385	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EGM95_RS19390	COG0795	lipopolysaccharide-transporting ATPase activity
EGM95_RS19430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGM95_RS19430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EGM95_RS19440	COG0004	ammonium transporteR
EGM95_RS19445	COG0347	Belongs to the P(II) protein family
EGM95_RS19455	COG0606	chelatase, subunit chli
EGM95_RS19460	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EGM95_RS19470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EGM95_RS19485	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EGM95_RS19505	COG0318	PFAM AMP-dependent synthetase and ligase
EGM95_RS19515	COG0477	Major facilitator Superfamily
EGM95_RS19520	COG2860	membrane
EGM95_RS19530	COG1253	flavin adenine dinucleotide binding
EGM95_RS19540	COG2814	Major facilitator Superfamily
EGM95_RS19550	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EGM95_RS19585	COG0655	NAD(P)H dehydrogenase (quinone) activity
EGM95_RS19595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EGM95_RS19630	COG1309	transcriptional regulator
EGM95_RS19665	COG0758	DNA mediated transformation
EGM95_RS19675	COG0697	spore germination
EGM95_RS19680	COG1309	transcriptional regulator
EGM95_RS19695	COG0386	Belongs to the glutathione peroxidase family
EGM95_RS19760	COG1121	(ABC) transporter
EGM95_RS19765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EGM95_RS19770	COG1280	lysine exporter protein (LysE YggA)
EGM95_RS19775	COG2837	iron assimilation
EGM95_RS19790	COG0281	malic enzyme
EGM95_RS19835	COG0519	Catalyzes the synthesis of GMP from XMP
EGM95_RS19835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EGM95_RS19840	COG4399	Belongs to the UPF0754 family
EGM95_RS19845	COG2259	Doxx family
EGM95_RS19850	COG0586	Pfam SNARE associated Golgi protein
EGM95_RS19865	COG1192	Involved in chromosome partitioning
EGM95_RS19875	COG0271	Belongs to the BolA IbaG family
EGM95_RS19895	COG1024	Enoyl-CoA hydratase
EGM95_RS19900	COG1024	Enoyl-CoA hydratase
EGM95_RS19905	COG1960	acyl-CoA dehydrogenase activity
EGM95_RS19910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EGM95_RS19930	COG1113	amino acid transport
EGM95_RS19935	COG1113	amino acid transport
EGM95_RS19940	COG0251	oxidation-reduction process
EGM95_RS19980	COG0564	pseudouridine synthase activity
EGM95_RS20050	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EGM95_RS20065	COG1802	Transcriptional regulator
EGM95_RS20075	COG1448	Aminotransferase
EGM95_RS20080	COG0277	FAD linked oxidase domain protein
EGM95_RS20090	COG2186	Transcriptional regulator
EGM95_RS20100	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EGM95_RS20105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EGM95_RS20120	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EGM95_RS20125	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EGM95_RS20130	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
EGM95_RS20175	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS20180	COG1083	cytidylyl-transferase
EGM95_RS20185	COG0673	inositol 2-dehydrogenase activity
EGM95_RS20190	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EGM95_RS20195	COG1045	serine acetyltransferase
EGM95_RS20200	COG2089	acid synthase
EGM95_RS20205	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
EGM95_RS20210	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EGM95_RS20220	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EGM95_RS20225	COG1596	polysaccharide export
EGM95_RS20250	COG0728	peptidoglycan biosynthetic process
EGM95_RS20255	COG3023	N-Acetylmuramoyl-L-alanine amidase
EGM95_RS20315	COG0546	phosphoglycolate phosphatase activity
EGM95_RS20320	COG1028	Short-chain dehydrogenase reductase Sdr
EGM95_RS20340	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGM95_RS20345	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EGM95_RS20350	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EGM95_RS20355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EGM95_RS20360	COG1116	anion transmembrane transporter activity
EGM95_RS20365	COG1309	transcriptional regulator
EGM95_RS20370	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EGM95_RS20385	COG0196	riboflavin kinase activity
EGM95_RS20390	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EGM95_RS20400	COG1047	Peptidyl-prolyl cis-trans
EGM95_RS20440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EGM95_RS20445	COG0657	acetylesterase activity
EGM95_RS20495	COG2951	lytic endotransglycosylase activity
EGM95_RS20500	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EGM95_RS20520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EGM95_RS20555	COG0671	phosphoesterase, PA-phosphatase related
EGM95_RS20560	COG0861	Integral membrane protein TerC family
EGM95_RS20570	COG0754	glutathionylspermidine amidase activity
EGM95_RS20580	COG0402	S-adenosylhomocysteine deaminase activity
EGM95_RS20595	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EGM95_RS20600	COG1230	cation diffusion facilitator family transporter
EGM95_RS20615	COG0706	membrane insertase activity
EGM95_RS20770	COG1192	Involved in chromosome partitioning
EGM95_RS20795	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
EGM95_RS20810	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
EGM95_RS20900	COG2026	Addiction module toxin, RelE StbE family
EGM95_RS20975	COG1192	Involved in chromosome partitioning