locus-tag	class	description
MS14413_RS00050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MS14413_RS00050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
MS14413_RS00075	COG3539	Fimbrial protein
MS14413_RS00080	COG3121	Chaperone
MS14413_RS00105	COG0697	spore germination
MS14413_RS00115	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MS14413_RS00125	COG0583	DNA-binding transcription factor activity
MS14413_RS00145	COG1309	transcriptional regulator
MS14413_RS00160	COG1522	sequence-specific DNA binding
MS14413_RS00170	COG1126	abc transporter atp-binding protein
MS14413_RS00175	COG0765	amino acid transport
MS14413_RS00180	COG0765	amino acid transport
MS14413_RS00210	COG1464	Belongs to the NlpA lipoprotein family
MS14413_RS00220	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MS14413_RS00225	COG2011	ABC-type metal ion transport system permease component
MS14413_RS00230	COG0012	GTP binding
MS14413_RS00255	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MS14413_RS00295	COG0386	Belongs to the glutathione peroxidase family
MS14413_RS00305	COG0436	Aminotransferase
MS14413_RS00345	COG3634	alkyl hydroperoxide reductase activity
MS14413_RS00360	COG0583	DNA-binding transcription factor activity
MS14413_RS00365	COG0798	PFAM Bile acid sodium symporter
MS14413_RS00370	COG0640	Transcriptional regulator
MS14413_RS00385	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MS14413_RS00395	COG0583	DNA-binding transcription factor activity
MS14413_RS00405	COG1953	Uracil, thiamine, allantoin
MS14413_RS00415	COG2175	clavaminate synthase activity
MS14413_RS00420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MS14413_RS00425	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MS14413_RS00430	COG4521	taurine ABC transporter
MS14413_RS00440	COG0477	Major facilitator Superfamily
MS14413_RS00460	COG1271	oxidase subunit
MS14413_RS00465	COG1294	oxidase, subunit
MS14413_RS00475	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS14413_RS00495	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MS14413_RS00515	COG3052	prosthetic group binding
MS14413_RS00520	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
MS14413_RS00530	COG2814	Major facilitator Superfamily
MS14413_RS00550	COG1346	cytolysis
MS14413_RS00560	COG0583	DNA-binding transcription factor activity
MS14413_RS00565	COG0625	glutathione transferase activity
MS14413_RS00570	COG0625	glutathione transferase activity
MS14413_RS00575	COG0583	DNA-binding transcription factor activity
MS14413_RS00590	COG1045	serine acetyltransferase
MS14413_RS00595	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MS14413_RS00600	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MS14413_RS00610	COG1280	lysine exporter protein (LysE YggA)
MS14413_RS00625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS14413_RS00630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS14413_RS00635	COG1126	abc transporter atp-binding protein
MS14413_RS00640	COG0765	amino acid transport
MS14413_RS00645	COG0765	amino acid transport
MS14413_RS00665	COG0784	Response regulator, receiver
MS14413_RS00665	COG2205	protein histidine kinase activity
MS14413_RS00685	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MS14413_RS00705	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS00755	COG0583	DNA-binding transcription factor activity
MS14413_RS00775	COG0318	PFAM AMP-dependent synthetase and ligase
MS14413_RS00780	COG1309	transcriptional regulator
MS14413_RS00785	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS00790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MS14413_RS00795	COG1024	Enoyl-CoA hydratase
MS14413_RS00800	COG4770	biotin carboxylase activity
MS14413_RS00810	COG0583	DNA-binding transcription factor activity
MS14413_RS00825	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS00835	COG2814	Major facilitator Superfamily
MS14413_RS00845	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MS14413_RS00850	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MS14413_RS00855	COG2814	Major facilitator Superfamily
MS14413_RS00860	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS00865	COG1024	Enoyl-CoA hydratase
MS14413_RS00870	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS00875	COG1250	3-hydroxyacyl-CoA dehydrogenase
MS14413_RS00880	COG0183	Belongs to the thiolase family
MS14413_RS00890	COG2814	Major facilitator Superfamily
MS14413_RS00900	COG1024	Enoyl-CoA hydratase
MS14413_RS00915	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS00920	COG2814	Major facilitator Superfamily
MS14413_RS00925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS14413_RS00930	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
MS14413_RS00945	COG3842	ATPase activity
MS14413_RS00950	COG1840	ABC-type Fe3 transport system, periplasmic component
MS14413_RS00960	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS14413_RS00965	COG1414	Transcriptional regulator
MS14413_RS00975	COG0583	DNA-binding transcription factor activity
MS14413_RS00980	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS14413_RS00985	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS00995	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
MS14413_RS01005	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS01010	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS14413_RS01015	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS14413_RS01020	COG2267	carboxylic ester hydrolase activity
MS14413_RS01040	COG3038	cytochrome b561
MS14413_RS01045	COG0753	catalase activity
MS14413_RS01080	COG2050	protein possibly involved in aromatic compounds catabolism
MS14413_RS01090	COG3327	negative regulation of DNA-templated transcription, initiation
MS14413_RS01095	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
MS14413_RS01100	COG0183	Belongs to the thiolase family
MS14413_RS01105	COG1250	3-hydroxyacyl-CoA dehydrogenase
MS14413_RS01110	COG1024	Enoyl-CoA hydratase
MS14413_RS01115	COG1024	Enoyl-CoA hydratase
MS14413_RS01120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS14413_RS01125	COG2151	metal-sulfur cluster biosynthetic enzyme
MS14413_RS01130	COG3396	Phenylacetate-CoA oxygenase
MS14413_RS01135	COG3460	Phenylacetate-CoA oxygenase
MS14413_RS01140	COG3396	Phenylacetate-CoA oxygenase
MS14413_RS01145	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS01145	COG2030	dehydratase
MS14413_RS01150	COG1760	l-serine dehydratase
MS14413_RS01155	COG0531	amino acid
MS14413_RS01160	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS01175	COG0446	pyridine nucleotide-disulphide oxidoreductase
MS14413_RS01185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MS14413_RS01205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MS14413_RS01215	COG0789	Transcriptional regulator
MS14413_RS01230	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MS14413_RS01245	COG2807	transmembrane transport
MS14413_RS01250	COG0590	tRNA wobble adenosine to inosine editing
MS14413_RS01365	COG1116	anion transmembrane transporter activity
MS14413_RS01370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MS14413_RS01380	COG0864	Transcriptional regulator
MS14413_RS01400	COG2249	NAD(P)H dehydrogenase (quinone) activity
MS14413_RS01405	COG0439	Biotin carboxylase
MS14413_RS01420	COG1063	alcohol dehydrogenase
MS14413_RS01430	COG1309	transcriptional regulator
MS14413_RS01450	COG0038	chloride channel
MS14413_RS01455	COG4770	biotin carboxylase activity
MS14413_RS01475	COG1914	H( )-stimulated, divalent metal cation uptake system
MS14413_RS01480	COG0583	DNA-binding transcription factor activity
MS14413_RS01495	COG3209	COG3209 Rhs family protein
MS14413_RS01500	COG3501	Rhs element vgr protein
MS14413_RS01505	COG2826	transposase and inactivated derivatives, IS30 family
MS14413_RS01535	COG1250	3-hydroxyacyl-CoA dehydrogenase
MS14413_RS01555	COG2814	Major facilitator Superfamily
MS14413_RS01565	COG1560	Kdo2-lipid A biosynthetic process
MS14413_RS01575	COG5006	permease, DMT superfamily
MS14413_RS01580	COG1522	sequence-specific DNA binding
MS14413_RS01595	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MS14413_RS01605	COG4122	O-methyltransferase activity
MS14413_RS01635	COG1538	Outer membrane efflux protein
MS14413_RS01640	COG1137	ATPase activity
MS14413_RS01645	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
MS14413_RS01655	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MS14413_RS01660	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MS14413_RS01660	COG0517	IMP dehydrogenase activity
MS14413_RS01695	COG2814	Major facilitator Superfamily
MS14413_RS01730	COG1278	Cold shock
MS14413_RS01735	COG1280	lysine exporter protein (LysE YggA)
MS14413_RS01765	COG1570	exodeoxyribonuclease VII activity
MS14413_RS01815	COG0583	DNA-binding transcription factor activity
MS14413_RS01825	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MS14413_RS01830	COG0633	Ferredoxin
MS14413_RS01830	COG0543	2 iron, 2 sulfur cluster binding
MS14413_RS01835	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS01840	COG3135	benzoate transporter
MS14413_RS01845	COG2814	Major facilitator Superfamily
MS14413_RS01860	COG1643	Atp-dependent helicase
MS14413_RS01865	COG0450	alkyl hydroperoxide reductase
MS14413_RS01875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MS14413_RS01890	COG3634	alkyl hydroperoxide reductase activity
MS14413_RS01910	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MS14413_RS01915	COG0625	glutathione transferase activity
MS14413_RS01925	COG2885	chlorophyll binding
MS14413_RS01960	COG0542	response to heat
MS14413_RS01975	COG1765	OsmC-like protein
MS14413_RS01995	COG0667	Aldo Keto reductase
MS14413_RS02010	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MS14413_RS02020	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MS14413_RS02030	COG0527	aspartate kinase activity
MS14413_RS02040	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MS14413_RS02050	COG3038	cytochrome b561
MS14413_RS02055	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MS14413_RS02060	COG2252	PERMEase
MS14413_RS02080	COG2072	flavoprotein involved in K transport
MS14413_RS02105	COG1794	racemase activity, acting on amino acids and derivatives
MS14413_RS02115	COG3008	intermembrane lipid transfer
MS14413_RS02115	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MS14413_RS02120	COG2995	paraquat-inducible protein a
MS14413_RS02130	COG2985	domain, Protein
MS14413_RS02155	COG0477	Major facilitator Superfamily
MS14413_RS02195	COG2826	transposase and inactivated derivatives, IS30 family
MS14413_RS02210	COG2186	Transcriptional regulator
MS14413_RS02220	COG0786	glutamate:sodium symporter activity
MS14413_RS02225	COG3243	poly(R)-hydroxyalkanoic acid synthase
MS14413_RS02250	COG3111	PFAM Bacterial OB fold (BOF) protein
MS14413_RS02350	COG1610	YqeY-like protein
MS14413_RS02355	COG4783	chaperone-mediated protein folding
MS14413_RS02380	COG1286	toxin biosynthetic process
MS14413_RS02410	COG0778	Nitroreductase
MS14413_RS02420	COG0513	Belongs to the DEAD box helicase family
MS14413_RS02440	COG2363	Small membrane protein
MS14413_RS02470	COG1234	tRNA 3'-trailer cleavage
MS14413_RS02475	COG2195	Cleaves the N-terminal amino acid of tripeptides
MS14413_RS02485	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MS14413_RS02495	COG2819	hydrolase of the alpha beta superfamily
MS14413_RS02500	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS02505	COG1301	dicarboxylic acid transport
MS14413_RS02510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MS14413_RS02515	COG3139	Protein of unknown function (DUF1315)
MS14413_RS02520	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MS14413_RS02525	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MS14413_RS02535	COG0494	nUDIX hydrolase
MS14413_RS02545	COG0642	Histidine kinase
MS14413_RS02550	COG0745	RESPONSE REGULATOR receiver
MS14413_RS02570	COG1720	tRNA m6t6A37 methyltransferase activity
MS14413_RS02585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS14413_RS02595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS14413_RS02605	COG4598	ABC transporter
MS14413_RS02610	COG4160	amino acid transport
MS14413_RS02615	COG4215	(ABC) transporter
MS14413_RS02630	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS14413_RS02675	COG1131	(ABC) transporter
MS14413_RS02680	COG0842	Transport permease protein
MS14413_RS02695	COG0772	Belongs to the SEDS family
MS14413_RS02700	COG2951	lytic endotransglycosylase activity
MS14413_RS02725	COG2207	Transcriptional regulator
MS14413_RS02740	COG0052	Belongs to the universal ribosomal protein uS2 family
MS14413_RS02745	COG0024	Methionine aminopeptidase
MS14413_RS02755	COG2223	nitrite transmembrane transporter activity
MS14413_RS02765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS14413_RS02770	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MS14413_RS02775	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS02790	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MS14413_RS02795	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MS14413_RS02800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MS14413_RS02820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MS14413_RS02825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MS14413_RS02830	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MS14413_RS02865	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MS14413_RS02875	COG0174	glutamine synthetase
MS14413_RS02880	COG3104	oligopeptide transport
MS14413_RS02890	COG0582	viral genome integration into host DNA
MS14413_RS03045	COG5410	chromosome segregation
MS14413_RS03235	COG0512	Glutamine amidotransferase of anthranilate synthase
MS14413_RS03240	COG0308	aminopeptidase N
MS14413_RS03270	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MS14413_RS03305	COG3739	integral membrane protein
MS14413_RS03320	COG1169	isochorismate synthase
MS14413_RS03330	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
MS14413_RS03340	COG1132	(ABC) transporter
MS14413_RS03355	COG3433	isochorismatase activity
MS14413_RS03355	COG1535	isochorismatase
MS14413_RS03360	COG1021	2,3-dihydroxybenzoate-AMP ligase
MS14413_RS03365	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MS14413_RS03375	COG4774	siderophore transport
MS14413_RS03380	COG4607	ABC-type enterochelin transport system periplasmic component
MS14413_RS03385	COG4604	ABC transporter, ATP-binding protein
MS14413_RS03390	COG4605	iron ion homeostasis
MS14413_RS03395	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MS14413_RS03400	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MS14413_RS03415	COG2964	Protein conserved in bacteria
MS14413_RS03425	COG1741	Belongs to the pirin family
MS14413_RS03445	COG1309	transcriptional regulator
MS14413_RS03455	COG4948	Mandelate Racemase Muconate Lactonizing
MS14413_RS03460	COG2814	Major facilitator Superfamily
MS14413_RS03495	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MS14413_RS03495	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MS14413_RS03500	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MS14413_RS03505	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS03515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS14413_RS03520	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS14413_RS03525	COG0583	DNA-binding transcription factor activity
MS14413_RS03530	COG1113	amino acid transport
MS14413_RS03550	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
MS14413_RS03550	COG2508	Transcriptional regulator
MS14413_RS03580	COG2879	small protein
MS14413_RS03585	COG1966	Carbon starvation protein
MS14413_RS03630	COG1067	ATP-dependent peptidase activity
MS14413_RS03635	COG0583	DNA-binding transcription factor activity
MS14413_RS03660	COG1686	Belongs to the peptidase S11 family
MS14413_RS03665	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
MS14413_RS03700	COG0616	signal peptide processing
MS14413_RS03705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MS14413_RS03715	COG0573	inorganic phosphate transmembrane transporter activity
MS14413_RS03720	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
MS14413_RS03725	COG1113	amino acid transport
MS14413_RS03730	COG3961	Belongs to the TPP enzyme family
MS14413_RS03735	COG1522	sequence-specific DNA binding
MS14413_RS03745	COG0076	glutamate decarboxylase activity
MS14413_RS03750	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MS14413_RS03760	COG1309	transcriptional regulator
MS14413_RS03775	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS14413_RS03810	COG0352	thiamine-phosphate diphosphorylase activity
MS14413_RS03835	COG0612	Peptidase, M16
MS14413_RS03850	COG0583	DNA-binding transcription factor activity
MS14413_RS03855	COG0477	Major facilitator Superfamily
MS14413_RS03880	COG1187	pseudouridine synthase activity
MS14413_RS03895	COG1686	Belongs to the peptidase S11 family
MS14413_RS03900	COG1252	NADH dehydrogenase
MS14413_RS03910	COG0415	Belongs to the DNA photolyase family
MS14413_RS03925	COG1215	transferase activity, transferring glycosyl groups
MS14413_RS03955	COG2070	2-Nitropropane dioxygenase
MS14413_RS04010	COG0556	nucleotide-excision repair
MS14413_RS04030	COG0436	Aminotransferase
MS14413_RS04060	COG4221	oxidoreductase activity
MS14413_RS04070	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MS14413_RS04075	COG1381	Involved in DNA repair and RecF pathway recombination
MS14413_RS04085	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MS14413_RS04100	COG0681	Belongs to the peptidase S26 family
MS14413_RS04115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MS14413_RS04135	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MS14413_RS04140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
MS14413_RS04145	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MS14413_RS04155	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MS14413_RS04160	COG4208	sulfate ABC transporter
MS14413_RS04165	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MS14413_RS04170	COG0583	DNA-binding transcription factor activity
MS14413_RS04175	COG4625	pathogenesis
MS14413_RS04190	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MS14413_RS04205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MS14413_RS04215	COG1051	belongs to the nudix hydrolase family
MS14413_RS04215	COG1056	cytidyltransferase-related domain
MS14413_RS04220	COG1024	Enoyl-CoA hydratase
MS14413_RS04230	COG2814	Major facilitator Superfamily
MS14413_RS04235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MS14413_RS04235	COG0047	phosphoribosylformylglycinamidine synthase activity
MS14413_RS04255	COG1473	amidohydrolase
MS14413_RS04260	COG0824	Thioesterase
MS14413_RS04280	COG0823	Involved in the tonB-independent uptake of proteins
MS14413_RS04300	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MS14413_RS04335	COG0628	permease
MS14413_RS04345	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MS14413_RS04350	COG0596	Alpha beta hydrolase
MS14413_RS04355	COG0616	signal peptide processing
MS14413_RS04355	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
MS14413_RS04365	COG2333	competence protein COMEC
MS14413_RS04365	COG0658	competence protein
MS14413_RS04370	COG1136	(ABC) transporter
MS14413_RS04375	COG4591	ABC-type transport system involved in lipoprotein release permease component
MS14413_RS04410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS14413_RS04430	COG0463	Glycosyl transferase, family 2
MS14413_RS04460	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MS14413_RS04465	COG1280	lysine exporter protein (LysE YggA)
MS14413_RS04475	COG0019	diaminopimelate decarboxylase activity
MS14413_RS04485	COG1113	amino acid transport
MS14413_RS04500	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
MS14413_RS04510	COG3339	Conserved Protein
MS14413_RS04515	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MS14413_RS04520	COG0243	molybdopterin cofactor binding
MS14413_RS04525	COG1929	Belongs to the glycerate kinase type-1 family
MS14413_RS04540	COG0778	Nitroreductase
MS14413_RS04565	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MS14413_RS04580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MS14413_RS04600	COG0741	lytic transglycosylase activity
MS14413_RS04620	COG0584	glycerophosphoryl diester phosphodiesterase
MS14413_RS04650	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MS14413_RS04655	COG1597	lipid kinase activity
MS14413_RS04670	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MS14413_RS04675	COG0477	Major facilitator Superfamily
MS14413_RS04725	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
MS14413_RS04730	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MS14413_RS04755	COG0505	Belongs to the CarA family
MS14413_RS04775	COG0589	response to stress
MS14413_RS04790	COG2843	Capsule synthesis protein
MS14413_RS04825	COG2321	neutral zinc metallopeptidase
MS14413_RS04830	COG2354	Protein conserved in bacteria
MS14413_RS04850	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS14413_RS04875	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MS14413_RS04880	COG1053	succinate dehydrogenase
MS14413_RS04885	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MS14413_RS04890	COG2009	succinate dehydrogenase
MS14413_RS04930	COG2921	Belongs to the UPF0250 family
MS14413_RS04935	COG0321	lipoyl(octanoyl) transferase activity
MS14413_RS04950	COG0531	amino acid
MS14413_RS04960	COG1733	regulation of RNA biosynthetic process
MS14413_RS04965	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MS14413_RS04970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MS14413_RS04970	COG1648	precorrin-2 dehydrogenase activity
MS14413_RS04985	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MS14413_RS05015	COG0671	phosphoesterase, PA-phosphatase related
MS14413_RS05020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS14413_RS05030	COG1538	Outer membrane efflux protein
MS14413_RS05035	COG0393	Putative heavy-metal-binding
MS14413_RS05040	COG0393	Putative heavy-metal-binding
MS14413_RS05050	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS05060	COG0525	valine-tRNA ligase activity
MS14413_RS05080	COG0583	DNA-binding transcription factor activity
MS14413_RS05085	COG0004	ammonium transporteR
MS14413_RS05100	COG0745	RESPONSE REGULATOR receiver
MS14413_RS05105	COG2194	sulfuric ester hydrolase activity
MS14413_RS05125	COG1752	Esterase of the alpha-beta hydrolase superfamily
MS14413_RS05140	COG2315	Protein conserved in bacteria
MS14413_RS05145	COG0142	geranyltranstransferase activity
MS14413_RS05150	COG2828	Protein conserved in bacteria
MS14413_RS05155	COG1113	amino acid transport
MS14413_RS05175	COG2207	Transcriptional regulator
MS14413_RS05200	COG2249	NAD(P)H dehydrogenase (quinone) activity
MS14413_RS05210	COG0560	Phosphoserine phosphatase
MS14413_RS05220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
MS14413_RS05230	COG1530	ribonuclease E activity
MS14413_RS05235	COG0424	maF-like protein
MS14413_RS05240	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
MS14413_RS05245	COG1792	Involved in formation and maintenance of cell shape
MS14413_RS05250	COG1077	Cell shape determining protein MreB Mrl
MS14413_RS05255	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MS14413_RS05265	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MS14413_RS05295	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
MS14413_RS05300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MS14413_RS05305	COG1752	Esterase of the alpha-beta hydrolase superfamily
MS14413_RS05310	COG1115	amino acid carrier protein
MS14413_RS05330	COG2814	Major facilitator Superfamily
MS14413_RS05335	COG1289	transmembrane transporter activity
MS14413_RS05345	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MS14413_RS05385	COG1376	ErfK ybiS ycfS ynhG family protein
MS14413_RS05390	COG2832	Protein of unknown function (DUF454)
MS14413_RS05400	COG5510	response to toxic substance
MS14413_RS05420	COG0840	transmembrane signaling receptor activity
MS14413_RS05460	COG3422	double-strand break repair
MS14413_RS05465	COG2824	Alkylphosphonate utilization operon protein PhnA
MS14413_RS05470	COG3189	MarR family transcriptional regulator
MS14413_RS05480	COG0354	folic acid binding
MS14413_RS05485	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MS14413_RS05500	COG1902	pentaerythritol trinitrate reductase activity
MS14413_RS05515	COG4772	TonB-dependent receptor
MS14413_RS05520	COG2094	Belongs to the DNA glycosylase MPG family
MS14413_RS05560	COG2233	PERMEase
MS14413_RS05570	COG0833	amino acid
MS14413_RS05575	COG1690	Belongs to the RtcB family
MS14413_RS05585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MS14413_RS05585	COG2885	chlorophyll binding
MS14413_RS05595	COG0183	Belongs to the thiolase family
MS14413_RS05615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MS14413_RS05635	COG2207	Transcriptional regulator
MS14413_RS05640	COG0183	Belongs to the thiolase family
MS14413_RS05670	COG1272	protein, Hemolysin III
MS14413_RS05675	COG0477	Major facilitator Superfamily
MS14413_RS05690	COG0450	alkyl hydroperoxide reductase
MS14413_RS05710	COG0285	dihydrofolate synthase activity
MS14413_RS05760	COG2096	Adenosyltransferase
MS14413_RS05780	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MS14413_RS05785	COG0745	RESPONSE REGULATOR receiver
MS14413_RS05790	COG2205	protein histidine kinase activity
MS14413_RS05800	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS05805	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS05810	COG0583	DNA-binding transcription factor activity
MS14413_RS05815	COG0625	glutathione transferase activity
MS14413_RS05880	COG0438	transferase activity, transferring glycosyl groups
MS14413_RS05885	COG0463	Glycosyl transferase, family 2
MS14413_RS05890	COG0726	polysaccharide deacetylase
MS14413_RS05910	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MS14413_RS05915	COG2205	protein histidine kinase activity
MS14413_RS05945	COG1862	Preprotein translocase
MS14413_RS05955	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MS14413_RS05960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MS14413_RS05970	COG3781	membrane
MS14413_RS05975	COG0613	PHP domain protein
MS14413_RS05985	COG2350	Protein conserved in bacteria
MS14413_RS06015	COG1607	acyl-coa hydrolase
MS14413_RS06075	COG2199	diguanylate cyclase activity
MS14413_RS06085	COG1408	metallophosphoesterase
MS14413_RS06090	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MS14413_RS06100	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MS14413_RS06120	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MS14413_RS06125	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MS14413_RS06140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MS14413_RS06150	COG2969	positive regulation of protein catabolic process
MS14413_RS06170	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS06175	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MS14413_RS06190	COG1309	transcriptional regulator
MS14413_RS06195	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS06240	COG1183	phosphatidylcholine synthase activity
MS14413_RS06245	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MS14413_RS06275	COG1196	nuclear chromosome segregation
MS14413_RS06275	COG0741	lytic transglycosylase activity
MS14413_RS06275	COG0739	heme binding
MS14413_RS06285	COG1702	phosphate starvation-inducible protein PhoH
MS14413_RS06320	COG1295	ribonuclease BN
MS14413_RS06325	COG0697	spore germination
MS14413_RS06330	COG2169	Transcriptional regulator
MS14413_RS06335	COG0179	Fumarylacetoacetate (FAA) hydrolase
MS14413_RS06380	COG0557	exoribonuclease II activity
MS14413_RS06385	COG0339	signal peptide processing
MS14413_RS06390	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
MS14413_RS06420	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MS14413_RS06425	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS06580	COG0626	cystathionine gamma-synthase activity
MS14413_RS06585	COG0433	COG0433 Predicted ATPase
MS14413_RS06590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS14413_RS06590	COG1017	nitric oxide dioxygenase activity
MS14413_RS06595	COG1959	2 iron, 2 sulfur cluster binding
MS14413_RS06610	COG1301	dicarboxylic acid transport
MS14413_RS06615	COG1946	Acyl-CoA thioesterase
MS14413_RS06635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MS14413_RS06640	COG1040	competence protein
MS14413_RS06645	COG0494	nUDIX hydrolase
MS14413_RS06655	COG0598	Magnesium transport protein CorA
MS14413_RS06665	COG2854	intermembrane phospholipid transfer
MS14413_RS06675	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MS14413_RS06680	COG1127	ABC transporter
MS14413_RS06690	COG0513	Belongs to the DEAD box helicase family
MS14413_RS06710	COG0408	coproporphyrinogen oxidase activity
MS14413_RS06730	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS06740	COG1983	PspC domain protein
MS14413_RS06745	COG0517	IMP dehydrogenase activity
MS14413_RS06790	COG0583	DNA-binding transcription factor activity
MS14413_RS06835	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS06845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MS14413_RS06850	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MS14413_RS06855	COG0833	amino acid
MS14413_RS06885	COG1192	Involved in chromosome partitioning
MS14413_RS06890	COG0628	permease
MS14413_RS06900	COG1289	transmembrane transporter activity
MS14413_RS06915	COG2249	NAD(P)H dehydrogenase (quinone) activity
MS14413_RS06920	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
MS14413_RS06930	COG0277	FAD linked oxidase domain protein
MS14413_RS06935	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MS14413_RS06960	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MS14413_RS06965	COG5380	lipid catabolic process
MS14413_RS06985	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MS14413_RS07035	COG0194	GDP metabolic process
MS14413_RS07050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MS14413_RS07075	COG3307	-O-antigen
MS14413_RS07095	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MS14413_RS07100	COG1704	LemA family
MS14413_RS07110	COG0493	'glutamate synthase
MS14413_RS07115	COG0070	glutamate synthase
MS14413_RS07115	COG0069	glutamate synthase activity
MS14413_RS07115	COG0067	glutamate synthase
MS14413_RS07165	COG2226	methyltransferase
MS14413_RS07180	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MS14413_RS07185	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MS14413_RS07230	COG0833	amino acid
MS14413_RS07315	COG0488	(ABC) transporter
MS14413_RS07320	COG2873	o-acetylhomoserine
MS14413_RS07325	COG4221	oxidoreductase activity
MS14413_RS07330	COG0659	secondary active sulfate transmembrane transporter activity
MS14413_RS07340	COG0745	RESPONSE REGULATOR receiver
MS14413_RS07355	COG0427	acetyl-CoA hydrolase
MS14413_RS07385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
MS14413_RS07415	COG2329	Antibiotic biosynthesis monooxygenase
MS14413_RS07430	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MS14413_RS07495	COG2249	NAD(P)H dehydrogenase (quinone) activity
MS14413_RS07500	COG1733	regulation of RNA biosynthetic process
MS14413_RS07530	COG0667	Aldo Keto reductase
MS14413_RS07550	COG0583	DNA-binding transcription factor activity
MS14413_RS07555	COG2814	Major facilitator Superfamily
MS14413_RS07585	COG1335	isochorismatase
MS14413_RS07595	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS07600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
MS14413_RS07610	COG1113	amino acid transport
MS14413_RS07620	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
MS14413_RS07635	COG2814	Major facilitator Superfamily
MS14413_RS07645	COG0352	thiamine-phosphate diphosphorylase activity
MS14413_RS07645	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MS14413_RS07645	COG0351	phosphomethylpyrimidine kinase
MS14413_RS07665	COG1309	transcriptional regulator
MS14413_RS07670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MS14413_RS07695	COG1061	Type III restriction enzyme res subunit
MS14413_RS07725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS14413_RS07735	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MS14413_RS07740	COG3162	membrane
MS14413_RS07745	COG2198	Histidine kinase
MS14413_RS07745	COG2205	protein histidine kinase activity
MS14413_RS07745	COG0784	Response regulator, receiver
MS14413_RS07770	COG3328	transposase activity
MS14413_RS07775	COG1522	sequence-specific DNA binding
MS14413_RS07780	COG1335	isochorismatase
MS14413_RS07785	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MS14413_RS07795	COG0668	transmembrane transport
MS14413_RS07800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MS14413_RS07805	COG1519	Transferase
MS14413_RS07810	COG1902	pentaerythritol trinitrate reductase activity
MS14413_RS07830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MS14413_RS07855	COG0426	domain, Protein
MS14413_RS07855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS14413_RS07860	COG4774	siderophore transport
MS14413_RS07865	COG2119	membrane
MS14413_RS07875	COG0508	dehydrogenase complex catalyzes the overall conversion of
MS14413_RS07885	COG4942	peptidase
MS14413_RS07900	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
MS14413_RS07910	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MS14413_RS07930	COG0189	ligase activity
MS14413_RS07950	COG0708	Exodeoxyribonuclease III
MS14413_RS07955	COG1393	Belongs to the ArsC family
MS14413_RS07970	COG3706	GGDEF domain
MS14413_RS08005	COG2351	hydroxyisourate hydrolase activity
MS14413_RS08010	COG2233	PERMEase
MS14413_RS08020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS14413_RS08030	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MS14413_RS08035	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS08045	COG3150	esterase
MS14413_RS08060	COG0791	NLP P60 protein
MS14413_RS08060	COG1388	LysM domain
MS14413_RS08065	COG3501	Rhs element vgr protein
MS14413_RS08075	COG2918	glutathione biosynthetic process
MS14413_RS08090	COG2733	membrane
MS14413_RS08095	COG0436	Aminotransferase
MS14413_RS08100	COG0534	Mate efflux family protein
MS14413_RS08200	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MS14413_RS08205	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MS14413_RS08215	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MS14413_RS08220	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MS14413_RS08235	COG0010	Belongs to the arginase family
MS14413_RS08265	COG2188	Transcriptional regulator
MS14413_RS08275	COG0523	cobalamin synthesis protein
MS14413_RS08285	COG1113	amino acid transport
MS14413_RS08295	COG0625	glutathione transferase activity
MS14413_RS08315	COG1683	Conserved Protein
MS14413_RS08320	COG0534	Mate efflux family protein
MS14413_RS08325	COG0385	Bile acid
MS14413_RS08330	COG1335	isochorismatase
MS14413_RS08335	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MS14413_RS08355	COG2116	formate transmembrane transporter activity
MS14413_RS08360	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MS14413_RS08365	COG2133	pyrroloquinoline quinone binding
MS14413_RS08370	COG2983	Belongs to the UPF0260 family
MS14413_RS08390	COG1194	a g-specific adenine glycosylase
MS14413_RS08405	COG2818	Glycosylase
MS14413_RS08410	COG1064	alcohol dehydrogenase
MS14413_RS08415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS14413_RS08430	COG0583	DNA-binding transcription factor activity
MS14413_RS08435	COG0656	L-ascorbic acid biosynthetic process
MS14413_RS08440	COG2814	Major facilitator Superfamily
MS14413_RS08475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS14413_RS08490	COG2233	PERMEase
MS14413_RS08530	COG0733	neurotransmitter:sodium symporter activity
MS14413_RS08575	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MS14413_RS08580	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MS14413_RS08585	COG0596	Alpha beta hydrolase
MS14413_RS08610	COG0488	(ABC) transporter
MS14413_RS08615	COG0586	Pfam SNARE associated Golgi protein
MS14413_RS08625	COG0187	DNA topoisomerase II activity
MS14413_RS08635	COG0592	DNA-directed DNA polymerase activity
MS14413_RS08665	COG0706	membrane insertase activity
MS14413_RS08680	COG1230	cation diffusion facilitator family transporter
MS14413_RS08685	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MS14413_RS08700	COG0402	S-adenosylhomocysteine deaminase activity
MS14413_RS08710	COG0754	glutathionylspermidine amidase activity
MS14413_RS08720	COG0861	Integral membrane protein TerC family
MS14413_RS08725	COG0671	phosphoesterase, PA-phosphatase related
MS14413_RS08735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MS14413_RS08750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MS14413_RS08755	COG2951	lytic endotransglycosylase activity
MS14413_RS08810	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MS14413_RS08850	COG1047	Peptidyl-prolyl cis-trans
MS14413_RS08860	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MS14413_RS08865	COG0196	riboflavin kinase activity
MS14413_RS08875	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MS14413_RS08880	COG1309	transcriptional regulator
MS14413_RS08885	COG1116	anion transmembrane transporter activity
MS14413_RS08890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MS14413_RS08895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS14413_RS08900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MS14413_RS08905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MS14413_RS08930	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS08935	COG0546	phosphoglycolate phosphatase activity
MS14413_RS08990	COG3023	N-Acetylmuramoyl-L-alanine amidase
MS14413_RS08995	COG0728	peptidoglycan biosynthetic process
MS14413_RS09010	COG2826	transposase and inactivated derivatives, IS30 family
MS14413_RS09030	COG1596	polysaccharide export
MS14413_RS09035	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MS14413_RS09045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
MS14413_RS09050	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MS14413_RS09055	COG2089	acid synthase
MS14413_RS09065	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MS14413_RS09070	COG1083	cytidylyl-transferase
MS14413_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS09085	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS09105	COG2826	transposase and inactivated derivatives, IS30 family
MS14413_RS09130	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MS14413_RS09145	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MS14413_RS09150	COG0110	maltose O-acetyltransferase activity
MS14413_RS09160	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MS14413_RS09175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MS14413_RS09180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MS14413_RS09190	COG2186	Transcriptional regulator
MS14413_RS09200	COG0277	FAD linked oxidase domain protein
MS14413_RS09225	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MS14413_RS09275	COG0564	pseudouridine synthase activity
MS14413_RS09310	COG1061	Type III restriction enzyme res subunit
MS14413_RS09340	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MS14413_RS09345	COG0110	maltose O-acetyltransferase activity
MS14413_RS09355	COG1210	Utp--glucose-1-phosphate uridylyltransferase
MS14413_RS09370	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MS14413_RS09375	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MS14413_RS09385	COG2186	Transcriptional regulator
MS14413_RS09395	COG0277	FAD linked oxidase domain protein
MS14413_RS09400	COG1448	Aminotransferase
MS14413_RS09405	COG1802	Transcriptional regulator
MS14413_RS09465	COG0564	pseudouridine synthase activity
MS14413_RS09500	COG1061	Type III restriction enzyme res subunit
MS14413_RS09540	COG0251	oxidation-reduction process
MS14413_RS09545	COG1113	amino acid transport
MS14413_RS09550	COG1113	amino acid transport
MS14413_RS09570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MS14413_RS09575	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS09580	COG1024	Enoyl-CoA hydratase
MS14413_RS09585	COG1024	Enoyl-CoA hydratase
MS14413_RS09590	COG0477	Major facilitator Superfamily
MS14413_RS09595	COG3916	Acyl-homoserine-lactone synthase
MS14413_RS09605	COG2197	response regulator
MS14413_RS09615	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS09620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MS14413_RS09620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MS14413_RS09620	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
MS14413_RS09620	COG3321	synthase
MS14413_RS09640	COG2267	carboxylic ester hydrolase activity
MS14413_RS09660	COG0271	Belongs to the BolA IbaG family
MS14413_RS09670	COG1192	Involved in chromosome partitioning
MS14413_RS09685	COG0586	Pfam SNARE associated Golgi protein
MS14413_RS09690	COG2259	Doxx family
MS14413_RS09695	COG4399	Belongs to the UPF0754 family
MS14413_RS09700	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MS14413_RS09700	COG0519	Catalyzes the synthesis of GMP from XMP
MS14413_RS09745	COG0281	malic enzyme
MS14413_RS09755	COG2837	iron assimilation
MS14413_RS09760	COG1280	lysine exporter protein (LysE YggA)
MS14413_RS09765	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MS14413_RS09770	COG1121	(ABC) transporter
MS14413_RS09840	COG0386	Belongs to the glutathione peroxidase family
MS14413_RS09855	COG1309	transcriptional regulator
MS14413_RS09860	COG0697	spore germination
MS14413_RS09870	COG0758	DNA mediated transformation
MS14413_RS09905	COG1309	transcriptional regulator
MS14413_RS09940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
MS14413_RS09950	COG0655	NAD(P)H dehydrogenase (quinone) activity
MS14413_RS09985	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MS14413_RS09995	COG0477	Major facilitator Superfamily
MS14413_RS10005	COG1253	flavin adenine dinucleotide binding
MS14413_RS10010	COG3012	SEC-C Motif Domain Protein
MS14413_RS10015	COG2860	membrane
MS14413_RS10020	COG0477	Major facilitator Superfamily
MS14413_RS10030	COG0318	PFAM AMP-dependent synthetase and ligase
MS14413_RS10045	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MS14413_RS10060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MS14413_RS10070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS14413_RS10075	COG0606	chelatase, subunit chli
MS14413_RS10105	COG0589	response to stress
MS14413_RS10110	COG0659	secondary active sulfate transmembrane transporter activity
MS14413_RS10140	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MS14413_RS10220	COG0606	chelatase, subunit chli
MS14413_RS10230	COG0347	Belongs to the P(II) protein family
MS14413_RS10235	COG0004	ammonium transporteR
MS14413_RS10245	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MS14413_RS10245	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MS14413_RS10285	COG0795	lipopolysaccharide-transporting ATPase activity
MS14413_RS10290	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
MS14413_RS10295	COG0793	Belongs to the peptidase S41A family
MS14413_RS10310	COG2197	response regulator
MS14413_RS10320	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MS14413_RS10330	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MS14413_RS10335	COG4974	Belongs to the 'phage' integrase family
MS14413_RS10360	COG0772	Belongs to the SEDS family
MS14413_RS10365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MS14413_RS10370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MS14413_RS10375	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MS14413_RS10400	COG0697	spore germination
MS14413_RS10405	COG1538	Outer membrane efflux protein
MS14413_RS10425	COG3275	phosphorelay sensor kinase activity
MS14413_RS10435	COG0181	hydroxymethylbilane synthase activity
MS14413_RS10480	COG1716	ATPase activity
MS14413_RS10485	COG0546	phosphoglycolate phosphatase activity
MS14413_RS10580	COG0596	Alpha beta hydrolase
MS14413_RS10585	COG2056	Na+-H+ antiporter family
MS14413_RS10600	COG0326	Molecular chaperone. Has ATPase activity
MS14413_RS10615	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
MS14413_RS10680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MS14413_RS10685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MS14413_RS10685	COG2169	Transcriptional regulator
MS14413_RS10715	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MS14413_RS10725	COG0497	DNA recombination
MS14413_RS10740	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MS14413_RS10750	COG0237	dephospho-CoA kinase activity
MS14413_RS10800	COG0195	Participates in both transcription termination and antitermination
MS14413_RS10820	COG2212	antiporter activity
MS14413_RS10830	COG0651	ATP synthesis coupled electron transport
MS14413_RS10835	COG1006	Multisubunit Na H antiporter MnhC subunit
MS14413_RS10840	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MS14413_RS10840	COG2111	Na H antiporter
MS14413_RS10855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MS14413_RS10860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS14413_RS10875	COG2226	methyltransferase
MS14413_RS10895	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
MS14413_RS10900	COG1074	ATP-dependent DNA helicase activity
MS14413_RS10905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MS14413_RS10925	COG0598	Magnesium transport protein CorA
MS14413_RS10930	COG0789	Transcriptional regulator
MS14413_RS10935	COG0484	heat shock protein binding
MS14413_RS10945	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MS14413_RS10950	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MS14413_RS10950	COG0475	glutathione-regulated potassium exporter activity
MS14413_RS10955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MS14413_RS10975	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MS14413_RS10985	COG4535	Mg2 and Co2 transporter CorC
MS14413_RS10990	COG0425	Belongs to the sulfur carrier protein TusA family
MS14413_RS10995	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
MS14413_RS10995	COG0644	oxidoreductase
MS14413_RS11005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
MS14413_RS11020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS14413_RS11025	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
MS14413_RS11065	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MS14413_RS11080	COG0534	Mate efflux family protein
MS14413_RS11090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MS14413_RS11095	COG4221	oxidoreductase activity
MS14413_RS11100	COG0583	DNA-binding transcription factor activity
MS14413_RS11115	COG0318	PFAM AMP-dependent synthetase and ligase
MS14413_RS11120	COG1530	ribonuclease E activity
MS14413_RS11130	COG0546	phosphoglycolate phosphatase activity
MS14413_RS11135	COG2378	regulation of single-species biofilm formation
MS14413_RS11140	COG0625	glutathione transferase activity
MS14413_RS11150	COG0583	DNA-binding transcription factor activity
MS14413_RS11215	COG0473	3-isopropylmalate dehydrogenase activity
MS14413_RS11270	COG1301	dicarboxylic acid transport
MS14413_RS11280	COG1560	Kdo2-lipid A biosynthetic process
MS14413_RS11285	COG1280	lysine exporter protein (LysE YggA)
MS14413_RS11295	COG2900	Belongs to the SlyX family
MS14413_RS11305	COG1733	regulation of RNA biosynthetic process
MS14413_RS11330	COG0210	DNA helicase
MS14413_RS11335	COG0724	RNA recognition motif
MS14413_RS11355	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MS14413_RS11355	COG4651	solute:proton antiporter activity
MS14413_RS11380	COG0788	formyltetrahydrofolate deformylase activity
MS14413_RS11480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MS14413_RS11480	COG2813	Specifically methylates the guanine in position
MS14413_RS11490	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MS14413_RS11500	COG4774	siderophore transport
MS14413_RS11510	COG0740	serine-type endopeptidase activity
MS14413_RS11530	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
MS14413_RS11530	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
MS14413_RS11535	COG0280	phosphate acetyltransferase
MS14413_RS11535	COG0857	belongs to the CobB CobQ family
MS14413_RS11540	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
MS14413_RS11550	COG0800	Aldolase
MS14413_RS11560	COG3265	gluconokinase activity
MS14413_RS11565	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS11575	COG2267	carboxylic ester hydrolase activity
MS14413_RS11590	COG0793	Belongs to the peptidase S41A family
MS14413_RS11625	COG1426	Protein conserved in bacteria
MS14413_RS11670	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MS14413_RS11680	COG0318	PFAM AMP-dependent synthetase and ligase
MS14413_RS11695	COG2986	histidine ammonia-lyase
MS14413_RS11735	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS11740	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MS14413_RS11760	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MS14413_RS11770	COG1162	GTPase activity
MS14413_RS11775	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MS14413_RS11790	COG1538	Outer membrane efflux protein
MS14413_RS11795	COG1136	(ABC) transporter
MS14413_RS11795	COG0577	efflux transmembrane transporter activity
MS14413_RS11800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS14413_RS11825	COG0028	Belongs to the TPP enzyme family
MS14413_RS11830	COG0440	acetolactate synthase activity
MS14413_RS11865	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MS14413_RS11880	COG0084	hydrolase, TatD family'
MS14413_RS11895	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MS14413_RS11905	COG0583	DNA-binding transcription factor activity
MS14413_RS11915	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MS14413_RS11920	COG2814	Major facilitator Superfamily
MS14413_RS11930	COG0697	spore germination
MS14413_RS11960	COG3622	Belongs to the hyi family
MS14413_RS11965	COG2084	Dehydrogenase
MS14413_RS11970	COG1024	Enoyl-CoA hydratase
MS14413_RS11975	COG2205	protein histidine kinase activity
MS14413_RS11975	COG5002	protein histidine kinase activity
MS14413_RS11975	COG0784	Response regulator, receiver
MS14413_RS11995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MS14413_RS12005	COG3956	TIGRFAM MazG family protein
MS14413_RS12010	COG1555	photosystem II stabilization
MS14413_RS12015	COG0617	tRNA 3'-terminal CCA addition
MS14413_RS12020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
MS14413_RS12040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS14413_RS12045	COG3028	Belongs to the UPF0307 family
MS14413_RS12050	COG0318	PFAM AMP-dependent synthetase and ligase
MS14413_RS12065	COG0625	glutathione transferase activity
MS14413_RS12070	COG1238	metal cluster binding
MS14413_RS12110	COG0072	phenylalanine-tRNA ligase activity
MS14413_RS12140	COG0248	Ppx GppA phosphatase
MS14413_RS12150	COG0037	tRNA processing
MS14413_RS12190	COG1764	response to oxidative stress
MS14413_RS12195	COG1846	Transcriptional regulator
MS14413_RS12205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MS14413_RS12265	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MS14413_RS12270	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MS14413_RS12275	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MS14413_RS12285	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MS14413_RS12335	COG1214	PFAM Peptidase M22, glycoprotease
MS14413_RS12360	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MS14413_RS12365	COG0561	phosphatase activity
MS14413_RS12375	COG2132	Multicopper oxidase
MS14413_RS12380	COG3667	copper resistance
MS14413_RS12395	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MS14413_RS12400	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MS14413_RS12405	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MS14413_RS12435	COG1063	alcohol dehydrogenase
MS14413_RS12440	COG0583	DNA-binding transcription factor activity
MS14413_RS12445	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS12450	COG2814	Major facilitator Superfamily
MS14413_RS12455	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MS14413_RS12465	COG1053	succinate dehydrogenase
MS14413_RS12470	COG0583	DNA-binding transcription factor activity
MS14413_RS12485	COG0583	DNA-binding transcription factor activity
MS14413_RS12495	COG1473	amidohydrolase
MS14413_RS12515	COG0583	DNA-binding transcription factor activity
MS14413_RS12530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS14413_RS12550	COG0384	phenazine biosynthesis protein PhzF
MS14413_RS12575	COG4993	Dehydrogenase
MS14413_RS12645	COG2205	protein histidine kinase activity
MS14413_RS12655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MS14413_RS12675	COG0745	RESPONSE REGULATOR receiver
MS14413_RS12680	COG2205	protein histidine kinase activity
MS14413_RS12715	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MS14413_RS12745	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MS14413_RS12750	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MS14413_RS12770	COG0583	DNA-binding transcription factor activity
MS14413_RS12790	COG0668	transmembrane transport
MS14413_RS12800	COG2081	HI0933 family
MS14413_RS12805	COG2515	1-aminocyclopropane-1-carboxylate deaminase
MS14413_RS12835	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MS14413_RS12835	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MS14413_RS12845	COG0489	protein tyrosine kinase activity
MS14413_RS12895	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MS14413_RS12905	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MS14413_RS12920	COG0730	response to heat
MS14413_RS12930	COG1196	nuclear chromosome segregation
MS14413_RS12950	COG2223	nitrite transmembrane transporter activity
MS14413_RS12955	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
MS14413_RS12960	COG1877	trehalose-phosphatase activity
MS14413_RS12965	COG2226	methyltransferase
MS14413_RS12965	COG0596	Alpha beta hydrolase
MS14413_RS12965	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MS14413_RS12980	COG4106	trans-aconitate 2-methyltransferase activity
MS14413_RS12995	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MS14413_RS13000	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MS14413_RS13005	COG0009	L-threonylcarbamoyladenylate synthase
MS14413_RS13010	COG3101	peptidyl-lysine hydroxylation
MS14413_RS13015	COG1399	metal-binding, possibly nucleic acid-binding protein
MS14413_RS13040	COG1652	LysM domain
MS14413_RS13045	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
MS14413_RS13045	COG0352	thiamine-phosphate diphosphorylase activity
MS14413_RS13045	COG0351	phosphomethylpyrimidine kinase
MS14413_RS13055	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
MS14413_RS13085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MS14413_RS13115	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MS14413_RS13130	COG0358	DNA primase activity
MS14413_RS13140	COG0564	pseudouridine synthase activity
MS14413_RS13165	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MS14413_RS13185	COG0583	DNA-binding transcription factor activity
MS14413_RS13190	COG0473	3-isopropylmalate dehydrogenase activity
MS14413_RS13210	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS13230	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MS14413_RS13230	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MS14413_RS13290	COG0456	acetyltransferase
MS14413_RS13300	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MS14413_RS13305	COG0492	ferredoxin-NADP+ reductase activity
MS14413_RS13310	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
MS14413_RS13310	COG1674	ftsk spoiiie
MS14413_RS13315	COG1280	lysine exporter protein (LysE YggA)
MS14413_RS13335	COG2894	cell division
MS14413_RS13350	COG0204	Acyl-transferase
MS14413_RS13355	COG2885	chlorophyll binding
MS14413_RS13360	COG0210	DNA helicase
MS14413_RS13370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MS14413_RS13385	COG0121	glutamine amidotransferase
MS14413_RS13405	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MS14413_RS13410	COG0735	belongs to the Fur family
MS14413_RS13435	COG0420	3'-5' exonuclease activity
MS14413_RS13455	COG1090	epimerase
MS14413_RS13470	COG2050	protein possibly involved in aromatic compounds catabolism
MS14413_RS13480	COG2814	Major facilitator Superfamily
MS14413_RS13485	COG0405	Gamma-glutamyltransferase
MS14413_RS13555	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MS14413_RS13645	COG1484	DNA-dependent DNA replication
MS14413_RS13690	COG3755	Protein conserved in bacteria
MS14413_RS13840	COG2026	Addiction module toxin, RelE StbE family
MS14413_RS13880	COG0592	DNA-directed DNA polymerase activity
MS14413_RS13980	COG0084	hydrolase, TatD family'
MS14413_RS14000	COG0477	Major facilitator Superfamily
MS14413_RS14005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MS14413_RS14015	COG1595	DNA-templated transcription, initiation
MS14413_RS14070	COG0531	amino acid
MS14413_RS14075	COG2040	homocysteine
MS14413_RS14100	COG1309	transcriptional regulator
MS14413_RS14105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS14413_RS14110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MS14413_RS14120	COG1607	acyl-coa hydrolase
MS14413_RS14130	COG0523	cobalamin synthesis protein
MS14413_RS14140	COG4681	YaeQ
MS14413_RS14150	COG1649	PFAM Uncharacterised BCR, COG1649
MS14413_RS14150	COG0726	polysaccharide deacetylase
MS14413_RS14155	COG1215	transferase activity, transferring glycosyl groups
MS14413_RS14165	COG1024	Enoyl-CoA hydratase
MS14413_RS14180	COG1414	Transcriptional regulator
MS14413_RS14200	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS14210	COG0446	pyridine nucleotide-disulphide oxidoreductase
MS14413_RS14215	COG2271	Major facilitator Superfamily
MS14413_RS14225	COG2267	carboxylic ester hydrolase activity
MS14413_RS14230	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS14245	COG0028	Belongs to the TPP enzyme family
MS14413_RS14255	COG0477	Major facilitator Superfamily
MS14413_RS14260	COG0242	peptide deformylase activity
MS14413_RS14265	COG2066	Belongs to the glutaminase family
MS14413_RS14270	COG2207	Transcriptional regulator
MS14413_RS14275	COG2223	nitrite transmembrane transporter activity
MS14413_RS14290	COG0583	DNA-binding transcription factor activity
MS14413_RS14295	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS14300	COG2271	Major facilitator Superfamily
MS14413_RS14305	COG3959	Transketolase, thiamine diphosphate binding domain
MS14413_RS14310	COG3958	Transketolase
MS14413_RS14320	COG0306	phosphate transporter
MS14413_RS14340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
MS14413_RS14385	COG4181	ATPase activity
MS14413_RS14390	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MS14413_RS14415	COG0583	DNA-binding transcription factor activity
MS14413_RS14425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MS14413_RS14430	COG1773	rubredoxin
MS14413_RS14480	COG2851	Citrate transporter
MS14413_RS14485	COG1253	flavin adenine dinucleotide binding
MS14413_RS14525	COG0804	urea catabolic process
MS14413_RS14535	COG0830	nickel cation binding
MS14413_RS14550	COG0742	ribosomal rna small subunit methyltransferase
MS14413_RS14555	COG0768	penicillin binding
MS14413_RS14580	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MS14413_RS14585	COG2878	Part of a membrane complex involved in electron transport
MS14413_RS14590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MS14413_RS14600	COG3384	dioxygenase
MS14413_RS14625	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MS14413_RS14950	COG0739	heme binding
MS14413_RS14995	COG2194	sulfuric ester hydrolase activity
MS14413_RS15050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MS14413_RS15065	COG0305	Participates in initiation and elongation during chromosome replication
MS14413_RS15160	COG4695	Portal protein
MS14413_RS15220	COG0739	heme binding
MS14413_RS15220	COG1196	nuclear chromosome segregation
MS14413_RS15220	COG0741	lytic transglycosylase activity
MS14413_RS15305	COG0006	proline dipeptidase activity
MS14413_RS15310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS14413_RS15315	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MS14413_RS15335	COG1279	arginine transmembrane transporter activity
MS14413_RS15340	COG0583	DNA-binding transcription factor activity
MS14413_RS15380	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MS14413_RS15385	COG0741	lytic transglycosylase activity
MS14413_RS15385	COG1388	LysM domain
MS14413_RS15385	COG0741	lytic transglycosylase activity
MS14413_RS15385	COG1388	LysM domain
MS14413_RS15395	COG4174	ABC transporter (Permease)
MS14413_RS15400	COG4239	(ABC) transporter, permease
MS14413_RS15405	COG4172	Belongs to the ABC transporter superfamily
MS14413_RS15425	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MS14413_RS15435	COG3706	GGDEF domain
MS14413_RS15435	COG5001	Diguanylate cyclase
MS14413_RS15435	COG4251	negative regulation of phosphorylation
MS14413_RS15435	COG2203	Gaf domain
MS14413_RS15445	COG1902	pentaerythritol trinitrate reductase activity
MS14413_RS15445	COG0446	pyridine nucleotide-disulphide oxidoreductase
MS14413_RS15460	COG4269	membrane
MS14413_RS15485	COG3501	Rhs element vgr protein
MS14413_RS15560	COG0482	sulfurtransferase activity
MS14413_RS15580	COG3173	Aminoglycoside phosphotransferase
MS14413_RS15590	COG2433	Pfam Transposase IS66
MS14413_RS15630	COG1301	dicarboxylic acid transport
MS14413_RS15640	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS14413_RS15645	COG2011	ABC-type metal ion transport system permease component
MS14413_RS15650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MS14413_RS15655	COG1464	Belongs to the NlpA lipoprotein family
MS14413_RS15660	COG0151	Belongs to the GarS family
MS14413_RS15665	COG0138	bifunctional purine biosynthesis protein purh
MS14413_RS15670	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
MS14413_RS15700	COG2308	Evidence 4 Homologs of previously reported genes of
MS14413_RS15710	COG1305	Transglutaminase-like
MS14413_RS15720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MS14413_RS15725	COG0305	Participates in initiation and elongation during chromosome replication
MS14413_RS15750	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MS14413_RS15760	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MS14413_RS15765	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MS14413_RS15790	COG0726	polysaccharide deacetylase
MS14413_RS15790	COG1649	PFAM Uncharacterised BCR, COG1649
MS14413_RS15795	COG1215	transferase activity, transferring glycosyl groups
MS14413_RS15800	COG3658	cytochrome
MS14413_RS15810	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MS14413_RS15825	COG0583	DNA-binding transcription factor activity
MS14413_RS15845	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MS14413_RS15850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MS14413_RS15865	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS15870	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MS14413_RS15875	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS14413_RS15900	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MS14413_RS15905	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MS14413_RS15915	COG2205	protein histidine kinase activity
MS14413_RS15920	COG0745	RESPONSE REGULATOR receiver
MS14413_RS15925	COG0174	glutamine synthetase
MS14413_RS15945	COG0729	surface antigen
MS14413_RS15970	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MS14413_RS15975	COG2814	Major facilitator Superfamily
MS14413_RS15990	COG0583	DNA-binding transcription factor activity
MS14413_RS16005	COG1187	pseudouridine synthase activity
MS14413_RS16025	COG0802	atpase or kinase
MS14413_RS16030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MS14413_RS16040	COG1923	regulation of RNA biosynthetic process
MS14413_RS16045	COG0697	spore germination
MS14413_RS16060	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MS14413_RS16070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MS14413_RS16075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MS14413_RS16075	COG0519	Catalyzes the synthesis of GMP from XMP
MS14413_RS16080	COG4302	ethanolamine ammonia-lyase activity
MS14413_RS16085	COG4303	Ethanolamine ammonia lyase large subunit
MS14413_RS16090	COG0531	amino acid
MS14413_RS16110	COG1454	alcohol dehydrogenase
MS14413_RS16115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MS14413_RS16125	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
MS14413_RS16145	COG0308	aminopeptidase N
MS14413_RS16155	COG4221	oxidoreductase activity
MS14413_RS16165	COG1605	Chorismate mutase
MS14413_RS16180	COG1309	transcriptional regulator
MS14413_RS16190	COG0668	transmembrane transport
MS14413_RS16225	COG4773	Receptor
MS14413_RS16245	COG0488	(ABC) transporter
MS14413_RS16250	COG0589	response to stress
MS14413_RS16275	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MS14413_RS16285	COG3135	benzoate transporter
MS14413_RS16290	COG1522	sequence-specific DNA binding
MS14413_RS16300	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MS14413_RS16305	COG0583	DNA-binding transcription factor activity
MS14413_RS16315	COG0183	Belongs to the thiolase family
MS14413_RS16325	COG2030	dehydratase
MS14413_RS16345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MS14413_RS16355	COG0824	Thioesterase
MS14413_RS16360	COG1454	alcohol dehydrogenase
MS14413_RS16370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MS14413_RS16390	COG0069	glutamate synthase activity
MS14413_RS16575	COG5410	chromosome segregation
MS14413_RS16695	COG0739	heme binding
MS14413_RS16760	COG2194	sulfuric ester hydrolase activity
MS14413_RS16765	COG2814	Major facilitator Superfamily
MS14413_RS16780	COG0511	ligase activity, forming carbon-carbon bonds
MS14413_RS16800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MS14413_RS16800	COG1116	anion transmembrane transporter activity
MS14413_RS16805	COG0745	RESPONSE REGULATOR receiver
MS14413_RS16815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MS14413_RS16815	COG2146	nitrite reductase [NAD(P)H] activity
MS14413_RS16820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MS14413_RS16825	COG0243	molybdopterin cofactor binding
MS14413_RS16835	COG0243	molybdopterin cofactor binding
MS14413_RS16840	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MS14413_RS16855	COG0521	Mo-molybdopterin cofactor biosynthetic process
MS14413_RS16855	COG0315	cyclic pyranopterin monophosphate synthase activity
MS14413_RS16860	COG0303	'Molybdopterin
MS14413_RS16870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MS14413_RS16875	COG0697	spore germination
MS14413_RS16895	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
MS14413_RS16900	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MS14413_RS16955	COG2204	response regulator
MS14413_RS16960	COG3852	Histidine kinase
MS14413_RS16980	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MS14413_RS16985	COG0575	Belongs to the CDS family
MS14413_RS17020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MS14413_RS17035	COG2137	regulation of response to DNA damage stimulus
MS14413_RS17045	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MS14413_RS17050	COG1011	Hydrolase
MS14413_RS17075	COG1522	sequence-specific DNA binding
MS14413_RS17110	COG0659	secondary active sulfate transmembrane transporter activity
MS14413_RS17115	COG2135	peptidase activity
MS14413_RS17130	COG3300	MHYT domain
MS14413_RS17130	COG5001	Diguanylate cyclase
MS14413_RS17150	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS14413_RS17150	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
MS14413_RS17150	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
MS14413_RS17155	COG1105	Belongs to the carbohydrate kinase PfkB family
MS14413_RS17160	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
MS14413_RS17160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MS14413_RS17190	COG0024	Methionine aminopeptidase
MS14413_RS17195	COG0583	DNA-binding transcription factor activity
MS14413_RS17205	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MS14413_RS17210	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MS14413_RS17215	COG0516	GMP reductase activity
MS14413_RS17215	COG0517	IMP dehydrogenase activity
MS14413_RS17240	COG0552	protein localization to endoplasmic reticulum
MS14413_RS17250	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
MS14413_RS17265	COG4890	Cyd operon protein YbgT
MS14413_RS17270	COG1294	oxidase, subunit
MS14413_RS17290	COG1585	Membrane protein implicated in regulation of membrane protease activity
MS14413_RS17300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MS14413_RS17305	COG4774	siderophore transport
MS14413_RS17320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MS14413_RS17325	COG0569	domain protein
MS14413_RS17330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MS14413_RS17360	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MS14413_RS17365	COG0542	response to heat
MS14413_RS17390	COG0446	pyridine nucleotide-disulphide oxidoreductase
MS14413_RS17390	COG1902	pentaerythritol trinitrate reductase activity
MS14413_RS17435	COG2323	membrane
MS14413_RS17440	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MS14413_RS17450	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MS14413_RS17455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MS14413_RS17460	COG0183	Belongs to the thiolase family
MS14413_RS17465	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MS14413_RS17470	COG0596	Alpha beta hydrolase
MS14413_RS17475	COG2271	Major facilitator Superfamily
MS14413_RS17480	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MS14413_RS17485	COG3485	protocatechuate 3,4-dioxygenase
MS14413_RS17490	COG3485	protocatechuate 3,4-dioxygenase
MS14413_RS17495	COG0710	3-dehydroquinate dehydratase activity
MS14413_RS17505	COG3659	wide pore channel activity
MS14413_RS17510	COG4993	Dehydrogenase
MS14413_RS17520	COG2391	methyltransferase activity
MS14413_RS17535	COG1414	Transcriptional regulator
MS14413_RS17540	COG0583	DNA-binding transcription factor activity
MS14413_RS17545	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS17570	COG2814	Major facilitator Superfamily
MS14413_RS17580	COG0154	amidase activity
MS14413_RS17600	COG4638	Rieske (2fe-2S)
MS14413_RS17610	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS17620	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MS14413_RS17630	COG3733	amine oxidase
MS14413_RS17640	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS17650	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MS14413_RS17655	COG0183	Belongs to the thiolase family
MS14413_RS17660	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MS14413_RS17665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MS14413_RS17675	COG4829	muconolactone delta-isomerase
MS14413_RS17680	COG4948	Mandelate Racemase Muconate Lactonizing
MS14413_RS17685	COG0583	DNA-binding transcription factor activity
MS14413_RS17695	COG2186	Transcriptional regulator
MS14413_RS17715	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS17735	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS17740	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS17745	COG3829	transcription factor binding
MS14413_RS17755	COG3162	membrane
MS14413_RS17770	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS17785	COG0753	catalase activity
MS14413_RS17805	COG1846	Transcriptional regulator
MS14413_RS17810	COG0446	pyridine nucleotide-disulphide oxidoreductase
MS14413_RS17810	COG1902	pentaerythritol trinitrate reductase activity
MS14413_RS17820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MS14413_RS17850	COG1309	transcriptional regulator
MS14413_RS17860	COG1335	isochorismatase
MS14413_RS17865	COG0583	DNA-binding transcription factor activity
MS14413_RS17875	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MS14413_RS17875	COG0475	glutathione-regulated potassium exporter activity
MS14413_RS17880	COG2826	transposase and inactivated derivatives, IS30 family
MS14413_RS17890	COG1473	amidohydrolase
MS14413_RS17900	COG2831	hemolysin activation secretion protein
MS14413_RS17910	COG2826	transposase and inactivated derivatives, IS30 family
MS14413_RS17945	COG2188	Transcriptional regulator
MS14413_RS17960	COG0583	DNA-binding transcription factor activity
MS14413_RS17990	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MS14413_RS18010	COG1566	PFAM secretion protein HlyD family protein
MS14413_RS18025	COG1012	belongs to the aldehyde dehydrogenase family
MS14413_RS18030	COG0129	dihydroxy-acid dehydratase activity
MS14413_RS18040	COG0583	DNA-binding transcription factor activity
MS14413_RS18045	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MS14413_RS18055	COG2084	Dehydrogenase
MS14413_RS18060	COG2207	Transcriptional regulator
MS14413_RS18075	COG1064	alcohol dehydrogenase
MS14413_RS18090	COG1120	ATPase activity
MS14413_RS18110	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MS14413_RS18225	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MS14413_RS18275	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS18290	COG2207	Transcriptional regulator
MS14413_RS18300	COG2205	protein histidine kinase activity
MS14413_RS18305	COG0745	RESPONSE REGULATOR receiver
MS14413_RS18310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MS14413_RS18315	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS14413_RS18320	COG1538	Outer membrane efflux protein
MS14413_RS18330	COG2072	flavoprotein involved in K transport
MS14413_RS18350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MS14413_RS18370	COG3539	Fimbrial protein
MS14413_RS18400	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MS14413_RS18410	COG0753	catalase activity
MS14413_RS18425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MS14413_RS18490	COG3433	isochorismatase activity
MS14413_RS18490	COG1535	isochorismatase
MS14413_RS18495	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS18500	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MS14413_RS18505	COG4149	molybdate abc transporter
MS14413_RS18510	COG0725	ABC transporter, periplasmic molybdate-binding protein
MS14413_RS18520	COG4638	Rieske (2fe-2S)
MS14413_RS18525	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
MS14413_RS18530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MS14413_RS18530	COG0543	2 iron, 2 sulfur cluster binding
MS14413_RS18555	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS18570	COG2207	Transcriptional regulator
MS14413_RS18580	COG1028	Short-chain dehydrogenase reductase Sdr
MS14413_RS18585	COG2610	gluconate transmembrane transporter activity
MS14413_RS18595	COG0583	DNA-binding transcription factor activity
MS14413_RS18605	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MS14413_RS18610	COG2031	fatty acid transporter
MS14413_RS18615	COG0183	Belongs to the thiolase family
MS14413_RS18620	COG0583	DNA-binding transcription factor activity
MS14413_RS18625	COG0583	DNA-binding transcription factor activity
MS14413_RS18640	COG1027	Aspartate ammonia-lyase
MS14413_RS18650	COG0477	Major facilitator Superfamily
MS14413_RS18670	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MS14413_RS18675	COG4521	taurine ABC transporter
MS14413_RS18690	COG2188	Transcriptional regulator
MS14413_RS18700	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MS14413_RS18705	COG1733	regulation of RNA biosynthetic process
MS14413_RS18710	COG2207	Transcriptional regulator
MS14413_RS18710	COG3708	Transcriptional regulator
MS14413_RS18725	COG0730	response to heat
MS14413_RS18735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MS14413_RS18735	COG3453	Protein conserved in bacteria
MS14413_RS18745	COG3781	membrane
MS14413_RS18750	COG1063	alcohol dehydrogenase
MS14413_RS18760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MS14413_RS18765	COG0508	dehydrogenase complex catalyzes the overall conversion of
MS14413_RS18770	COG0022	dehydrogenase e1 component
MS14413_RS18775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
MS14413_RS18780	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MS14413_RS18795	COG3706	GGDEF domain
MS14413_RS18810	COG0133	tryptophan synthase activity
MS14413_RS18820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MS14413_RS18855	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MS14413_RS18880	COG2226	methyltransferase
MS14413_RS18935	COG0842	Transport permease protein
MS14413_RS18940	COG0842	Transport permease protein
MS14413_RS18945	COG1131	(ABC) transporter
MS14413_RS18960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MS14413_RS18965	COG4773	Receptor
MS14413_RS18985	COG0730	response to heat
MS14413_RS18990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MS14413_RS19010	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
MS14413_RS19025	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MS14413_RS19065	COG4264	IucA IucC family
MS14413_RS19070	COG4264	IucA IucC family
MS14413_RS19090	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MS14413_RS19105	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS19110	COG1960	acyl-CoA dehydrogenase activity
MS14413_RS19115	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MS14413_RS19120	COG2207	Transcriptional regulator
MS14413_RS19125	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MS14413_RS19130	COG0776	regulation of translation
MS14413_RS19155	COG0822	iron-sulfur transferase activity
MS14413_RS19160	COG0316	Belongs to the HesB IscA family
MS14413_RS19190	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MS14413_RS19210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MS14413_RS19215	COG0702	epimerase
MS14413_RS19250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MS14413_RS19260	COG0339	signal peptide processing
MS14413_RS19310	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MS14413_RS19315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MS14413_RS19345	COG0776	regulation of translation
MS14413_RS19410	COG0084	hydrolase, TatD family'
MS14413_RS19430	COG1663	tetraacyldisaccharide 4'-kinase activity
MS14413_RS19435	COG1132	(ABC) transporter
MS14413_RS19445	COG0811	peptide transport
MS14413_RS19450	COG1475	DNA binding
MS14413_RS19455	COG1192	Involved in chromosome partitioning
MS14413_RS19465	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MS14413_RS19480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MS14413_RS19485	COG0191	fructose-bisphosphate aldolase activity
MS14413_RS19505	COG0424	maF-like protein
MS14413_RS19510	COG2850	peptidyl-arginine hydroxylation
MS14413_RS19520	COG0640	Transcriptional regulator
MS14413_RS19530	COG3619	membrane
MS14413_RS19535	COG3122	Protein conserved in bacteria
MS14413_RS19540	COG1132	(ABC) transporter
MS14413_RS19560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MS14413_RS19565	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MS14413_RS19575	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MS14413_RS19575	COG0506	proline dehydrogenase activity
MS14413_RS19575	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MS14413_RS19580	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
MS14413_RS19595	COG3698	Phosphodiester glycosidase
MS14413_RS19605	COG2353	YceI-like domain