locus-tag	class	description
LO007_RS00020	COG0706	membrane insertase activity
LO007_RS00035	COG1230	cation diffusion facilitator family transporter
LO007_RS00040	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO007_RS00055	COG0402	S-adenosylhomocysteine deaminase activity
LO007_RS00065	COG0754	glutathionylspermidine amidase activity
LO007_RS00075	COG0861	Integral membrane protein TerC family
LO007_RS00080	COG0671	phosphoesterase, PA-phosphatase related
LO007_RS00090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LO007_RS00105	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LO007_RS00110	COG2951	lytic endotransglycosylase activity
LO007_RS00140	COG0583	DNA-binding transcription factor activity
LO007_RS00160	COG0657	acetylesterase activity
LO007_RS00165	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LO007_RS00205	COG1047	Peptidyl-prolyl cis-trans
LO007_RS00215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LO007_RS00220	COG0196	riboflavin kinase activity
LO007_RS00230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LO007_RS00235	COG1309	transcriptional regulator
LO007_RS00240	COG1116	anion transmembrane transporter activity
LO007_RS00245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO007_RS00250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO007_RS00255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO007_RS00260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO007_RS00280	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS00285	COG0546	phosphoglycolate phosphatase activity
LO007_RS00345	COG3023	N-Acetylmuramoyl-L-alanine amidase
LO007_RS00350	COG0728	peptidoglycan biosynthetic process
LO007_RS00380	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LO007_RS00390	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LO007_RS00415	COG1216	Glycosyl transferase, family 2
LO007_RS00415	COG0463	Glycosyl transferase, family 2
LO007_RS00420	COG0438	transferase activity, transferring glycosyl groups
LO007_RS00425	COG0438	transferase activity, transferring glycosyl groups
LO007_RS00435	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LO007_RS00440	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LO007_RS00455	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LO007_RS00465	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LO007_RS00475	COG2186	Transcriptional regulator
LO007_RS00485	COG0277	FAD linked oxidase domain protein
LO007_RS00490	COG1448	Aminotransferase
LO007_RS00500	COG1802	Transcriptional regulator
LO007_RS00515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LO007_RS00570	COG0564	pseudouridine synthase activity
LO007_RS00610	COG0251	oxidation-reduction process
LO007_RS00615	COG1113	amino acid transport
LO007_RS00620	COG1113	amino acid transport
LO007_RS00640	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO007_RS00645	COG1960	acyl-CoA dehydrogenase activity
LO007_RS00650	COG1024	Enoyl-CoA hydratase
LO007_RS00655	COG1024	Enoyl-CoA hydratase
LO007_RS00660	COG0477	Major facilitator Superfamily
LO007_RS00665	COG3916	Acyl-homoserine-lactone synthase
LO007_RS00675	COG2197	response regulator
LO007_RS00685	COG1960	acyl-CoA dehydrogenase activity
LO007_RS00690	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LO007_RS00690	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LO007_RS00690	COG3321	synthase
LO007_RS00690	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LO007_RS00730	COG0271	Belongs to the BolA IbaG family
LO007_RS00740	COG1192	Involved in chromosome partitioning
LO007_RS00755	COG0586	Pfam SNARE associated Golgi protein
LO007_RS00760	COG2259	Doxx family
LO007_RS00765	COG4399	Belongs to the UPF0754 family
LO007_RS00770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LO007_RS00770	COG0519	Catalyzes the synthesis of GMP from XMP
LO007_RS00815	COG0281	malic enzyme
LO007_RS00820	COG2837	iron assimilation
LO007_RS00825	COG1280	lysine exporter protein (LysE YggA)
LO007_RS00830	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LO007_RS00835	COG1121	(ABC) transporter
LO007_RS00900	COG0386	Belongs to the glutathione peroxidase family
LO007_RS00915	COG1309	transcriptional regulator
LO007_RS00920	COG0697	spore germination
LO007_RS00930	COG0758	DNA mediated transformation
LO007_RS00965	COG1309	transcriptional regulator
LO007_RS01000	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LO007_RS01015	COG0655	NAD(P)H dehydrogenase (quinone) activity
LO007_RS01055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LO007_RS01065	COG0477	Major facilitator Superfamily
LO007_RS01075	COG1253	flavin adenine dinucleotide binding
LO007_RS01085	COG2860	membrane
LO007_RS01090	COG0477	Major facilitator Superfamily
LO007_RS01100	COG0318	PFAM AMP-dependent synthetase and ligase
LO007_RS01115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LO007_RS01130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO007_RS01145	COG0606	chelatase, subunit chli
LO007_RS01155	COG0347	Belongs to the P(II) protein family
LO007_RS01160	COG0004	ammonium transporteR
LO007_RS01170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LO007_RS01170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LO007_RS01210	COG0795	lipopolysaccharide-transporting ATPase activity
LO007_RS01215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LO007_RS01220	COG0793	Belongs to the peptidase S41A family
LO007_RS01235	COG2197	response regulator
LO007_RS01245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LO007_RS01255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO007_RS01260	COG4974	Belongs to the 'phage' integrase family
LO007_RS01285	COG0772	Belongs to the SEDS family
LO007_RS01290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LO007_RS01295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LO007_RS01300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LO007_RS01325	COG0697	spore germination
LO007_RS01330	COG1538	Outer membrane efflux protein
LO007_RS01350	COG3275	phosphorelay sensor kinase activity
LO007_RS01360	COG0181	hydroxymethylbilane synthase activity
LO007_RS01405	COG1716	ATPase activity
LO007_RS01410	COG0546	phosphoglycolate phosphatase activity
LO007_RS01505	COG0596	Alpha beta hydrolase
LO007_RS01510	COG2056	Na+-H+ antiporter family
LO007_RS01525	COG0326	Molecular chaperone. Has ATPase activity
LO007_RS01540	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LO007_RS01595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LO007_RS01600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LO007_RS01600	COG2169	Transcriptional regulator
LO007_RS01630	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LO007_RS01640	COG0497	DNA recombination
LO007_RS01655	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LO007_RS01665	COG0237	dephospho-CoA kinase activity
LO007_RS01715	COG0195	Participates in both transcription termination and antitermination
LO007_RS01730	COG1320	monovalent cation:proton antiporter activity
LO007_RS01735	COG2212	antiporter activity
LO007_RS01740	COG1863	multisubunit Na H antiporter MnhE subunit
LO007_RS01745	COG0651	ATP synthesis coupled electron transport
LO007_RS01750	COG1006	Multisubunit Na H antiporter MnhC subunit
LO007_RS01755	COG2111	Na H antiporter
LO007_RS01755	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LO007_RS01770	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LO007_RS01775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO007_RS01790	COG2226	methyltransferase
LO007_RS01815	COG1074	ATP-dependent DNA helicase activity
LO007_RS01820	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LO007_RS01825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LO007_RS01840	COG0598	Magnesium transport protein CorA
LO007_RS01845	COG0789	Transcriptional regulator
LO007_RS01850	COG0484	heat shock protein binding
LO007_RS01865	COG0475	glutathione-regulated potassium exporter activity
LO007_RS01865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LO007_RS01870	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LO007_RS01890	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO007_RS01900	COG4535	Mg2 and Co2 transporter CorC
LO007_RS01905	COG0425	Belongs to the sulfur carrier protein TusA family
LO007_RS01915	COG0644	oxidoreductase
LO007_RS01915	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LO007_RS01925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LO007_RS01940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO007_RS01945	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LO007_RS01955	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO007_RS01955	COG0493	'glutamate synthase
LO007_RS01980	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LO007_RS01995	COG0534	Mate efflux family protein
LO007_RS02005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LO007_RS02010	COG4221	oxidoreductase activity
LO007_RS02015	COG0583	DNA-binding transcription factor activity
LO007_RS02030	COG0318	PFAM AMP-dependent synthetase and ligase
LO007_RS02035	COG1530	ribonuclease E activity
LO007_RS02045	COG0546	phosphoglycolate phosphatase activity
LO007_RS02050	COG2378	regulation of single-species biofilm formation
LO007_RS02055	COG0625	glutathione transferase activity
LO007_RS02065	COG0583	DNA-binding transcription factor activity
LO007_RS02120	COG0473	3-isopropylmalate dehydrogenase activity
LO007_RS02175	COG1301	dicarboxylic acid transport
LO007_RS02185	COG1560	Kdo2-lipid A biosynthetic process
LO007_RS02190	COG1280	lysine exporter protein (LysE YggA)
LO007_RS02200	COG0488	(ABC) transporter
LO007_RS02205	COG2900	Belongs to the SlyX family
LO007_RS02215	COG1733	regulation of RNA biosynthetic process
LO007_RS02240	COG0210	DNA helicase
LO007_RS02245	COG0724	RNA recognition motif
LO007_RS02265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LO007_RS02265	COG4651	solute:proton antiporter activity
LO007_RS02290	COG0788	formyltetrahydrofolate deformylase activity
LO007_RS02390	COG2813	Specifically methylates the guanine in position
LO007_RS02390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO007_RS02400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO007_RS02410	COG4774	siderophore transport
LO007_RS02420	COG0740	serine-type endopeptidase activity
LO007_RS02440	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LO007_RS02440	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LO007_RS02445	COG0857	belongs to the CobB CobQ family
LO007_RS02445	COG0280	phosphate acetyltransferase
LO007_RS02450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LO007_RS02460	COG0800	Aldolase
LO007_RS02470	COG3265	gluconokinase activity
LO007_RS02475	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS02485	COG2267	carboxylic ester hydrolase activity
LO007_RS02500	COG0793	Belongs to the peptidase S41A family
LO007_RS02535	COG1426	Protein conserved in bacteria
LO007_RS02575	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LO007_RS02585	COG1162	GTPase activity
LO007_RS02590	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LO007_RS02605	COG1538	Outer membrane efflux protein
LO007_RS02610	COG0577	efflux transmembrane transporter activity
LO007_RS02610	COG1136	(ABC) transporter
LO007_RS02615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO007_RS02640	COG0028	Belongs to the TPP enzyme family
LO007_RS02645	COG0440	acetolactate synthase activity
LO007_RS02675	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LO007_RS02690	COG0084	hydrolase, TatD family'
LO007_RS02705	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LO007_RS02715	COG0583	DNA-binding transcription factor activity
LO007_RS02725	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LO007_RS02815	COG2205	protein histidine kinase activity
LO007_RS02830	COG2132	Multicopper oxidase
LO007_RS02840	COG0789	Transcriptional regulator
LO007_RS02875	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LO007_RS02910	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LO007_RS02920	COG2814	Major facilitator Superfamily
LO007_RS02930	COG0697	spore germination
LO007_RS02960	COG3622	Belongs to the hyi family
LO007_RS02965	COG2084	Dehydrogenase
LO007_RS02970	COG1024	Enoyl-CoA hydratase
LO007_RS02975	COG0784	Response regulator, receiver
LO007_RS02975	COG2205	protein histidine kinase activity
LO007_RS02975	COG5002	protein histidine kinase activity
LO007_RS02995	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LO007_RS03005	COG3956	TIGRFAM MazG family protein
LO007_RS03010	COG1555	photosystem II stabilization
LO007_RS03015	COG0617	tRNA 3'-terminal CCA addition
LO007_RS03020	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LO007_RS03040	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LO007_RS03045	COG3028	Belongs to the UPF0307 family
LO007_RS03050	COG0318	PFAM AMP-dependent synthetase and ligase
LO007_RS03065	COG0625	glutathione transferase activity
LO007_RS03070	COG1238	metal cluster binding
LO007_RS03115	COG0072	phenylalanine-tRNA ligase activity
LO007_RS03145	COG0248	Ppx GppA phosphatase
LO007_RS03155	COG0037	tRNA processing
LO007_RS03195	COG1764	response to oxidative stress
LO007_RS03200	COG1846	Transcriptional regulator
LO007_RS03210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LO007_RS03270	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LO007_RS03275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LO007_RS03280	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LO007_RS03340	COG1214	PFAM Peptidase M22, glycoprotease
LO007_RS03365	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LO007_RS03370	COG0561	phosphatase activity
LO007_RS03380	COG2132	Multicopper oxidase
LO007_RS03400	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LO007_RS03405	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LO007_RS03410	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LO007_RS03440	COG1063	alcohol dehydrogenase
LO007_RS03445	COG0583	DNA-binding transcription factor activity
LO007_RS03450	COG1960	acyl-CoA dehydrogenase activity
LO007_RS03455	COG2814	Major facilitator Superfamily
LO007_RS03460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO007_RS03465	COG1309	transcriptional regulator
LO007_RS03480	COG1053	succinate dehydrogenase
LO007_RS03485	COG0583	DNA-binding transcription factor activity
LO007_RS03500	COG0583	DNA-binding transcription factor activity
LO007_RS03535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO007_RS03540	COG1309	transcriptional regulator
LO007_RS03565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LO007_RS03585	COG0745	RESPONSE REGULATOR receiver
LO007_RS03625	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LO007_RS03655	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LO007_RS03660	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO007_RS03680	COG0583	DNA-binding transcription factor activity
LO007_RS03700	COG0668	transmembrane transport
LO007_RS03710	COG2081	HI0933 family
LO007_RS03715	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LO007_RS03745	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO007_RS03745	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO007_RS03755	COG0489	protein tyrosine kinase activity
LO007_RS03805	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LO007_RS03815	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LO007_RS03830	COG0730	response to heat
LO007_RS03840	COG1196	nuclear chromosome segregation
LO007_RS03860	COG2223	nitrite transmembrane transporter activity
LO007_RS03865	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LO007_RS03870	COG1877	trehalose-phosphatase activity
LO007_RS03875	COG2226	methyltransferase
LO007_RS03875	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO007_RS03875	COG0596	Alpha beta hydrolase
LO007_RS03890	COG4106	trans-aconitate 2-methyltransferase activity
LO007_RS03905	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LO007_RS03910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LO007_RS03915	COG0009	L-threonylcarbamoyladenylate synthase
LO007_RS03920	COG3101	peptidyl-lysine hydroxylation
LO007_RS03925	COG1399	metal-binding, possibly nucleic acid-binding protein
LO007_RS03950	COG1652	LysM domain
LO007_RS03955	COG0351	phosphomethylpyrimidine kinase
LO007_RS03955	COG0352	thiamine-phosphate diphosphorylase activity
LO007_RS03955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LO007_RS03965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LO007_RS03995	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LO007_RS04025	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LO007_RS04040	COG0358	DNA primase activity
LO007_RS04050	COG0564	pseudouridine synthase activity
LO007_RS04075	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO007_RS04095	COG0583	DNA-binding transcription factor activity
LO007_RS04100	COG0473	3-isopropylmalate dehydrogenase activity
LO007_RS04110	COG0657	acetylesterase activity
LO007_RS04120	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS04140	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LO007_RS04140	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LO007_RS04155	COG1981	membrane
LO007_RS04200	COG0456	acetyltransferase
LO007_RS04210	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LO007_RS04215	COG0492	ferredoxin-NADP+ reductase activity
LO007_RS04220	COG1674	ftsk spoiiie
LO007_RS04220	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LO007_RS04225	COG1280	lysine exporter protein (LysE YggA)
LO007_RS04240	COG2894	cell division
LO007_RS04255	COG0204	Acyl-transferase
LO007_RS04260	COG2885	chlorophyll binding
LO007_RS04265	COG0210	DNA helicase
LO007_RS04275	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LO007_RS04290	COG0121	glutamine amidotransferase
LO007_RS04310	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO007_RS04315	COG0735	belongs to the Fur family
LO007_RS04340	COG0420	3'-5' exonuclease activity
LO007_RS04360	COG1090	epimerase
LO007_RS04375	COG2050	protein possibly involved in aromatic compounds catabolism
LO007_RS04385	COG2814	Major facilitator Superfamily
LO007_RS04390	COG0405	Gamma-glutamyltransferase
LO007_RS04445	COG0477	Major facilitator Superfamily
LO007_RS04450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO007_RS04475	COG0531	amino acid
LO007_RS04480	COG2040	homocysteine
LO007_RS04505	COG1309	transcriptional regulator
LO007_RS04510	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LO007_RS04515	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LO007_RS04525	COG1607	acyl-coa hydrolase
LO007_RS04535	COG0523	cobalamin synthesis protein
LO007_RS04545	COG4681	YaeQ
LO007_RS04555	COG0726	polysaccharide deacetylase
LO007_RS04555	COG1649	PFAM Uncharacterised BCR, COG1649
LO007_RS04560	COG1215	transferase activity, transferring glycosyl groups
LO007_RS04570	COG1024	Enoyl-CoA hydratase
LO007_RS04585	COG1414	Transcriptional regulator
LO007_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS04620	COG2271	Major facilitator Superfamily
LO007_RS04630	COG2267	carboxylic ester hydrolase activity
LO007_RS04635	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS04650	COG0028	Belongs to the TPP enzyme family
LO007_RS04660	COG0477	Major facilitator Superfamily
LO007_RS04665	COG0242	peptide deformylase activity
LO007_RS04670	COG2066	Belongs to the glutaminase family
LO007_RS04675	COG2207	Transcriptional regulator
LO007_RS04680	COG2223	nitrite transmembrane transporter activity
LO007_RS04695	COG0583	DNA-binding transcription factor activity
LO007_RS04700	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS04705	COG2271	Major facilitator Superfamily
LO007_RS04710	COG3959	Transketolase, thiamine diphosphate binding domain
LO007_RS04715	COG3958	Transketolase
LO007_RS04730	COG0306	phosphate transporter
LO007_RS04750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LO007_RS04795	COG4181	ATPase activity
LO007_RS04800	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LO007_RS04830	COG0583	DNA-binding transcription factor activity
LO007_RS04840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO007_RS04845	COG1773	rubredoxin
LO007_RS04895	COG2851	Citrate transporter
LO007_RS04900	COG1253	flavin adenine dinucleotide binding
LO007_RS04940	COG0804	urea catabolic process
LO007_RS04950	COG0830	nickel cation binding
LO007_RS04965	COG0742	ribosomal rna small subunit methyltransferase
LO007_RS04970	COG0768	penicillin binding
LO007_RS04995	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LO007_RS05000	COG2878	Part of a membrane complex involved in electron transport
LO007_RS05005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LO007_RS05015	COG3384	dioxygenase
LO007_RS05050	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LO007_RS05090	COG0006	proline dipeptidase activity
LO007_RS05095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO007_RS05100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO007_RS05120	COG1279	arginine transmembrane transporter activity
LO007_RS05125	COG0583	DNA-binding transcription factor activity
LO007_RS05165	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO007_RS05170	COG0741	lytic transglycosylase activity
LO007_RS05170	COG1388	LysM domain
LO007_RS05170	COG0741	lytic transglycosylase activity
LO007_RS05170	COG1388	LysM domain
LO007_RS05175	COG4166	transmembrane transport
LO007_RS05180	COG4174	ABC transporter (Permease)
LO007_RS05185	COG4239	(ABC) transporter, permease
LO007_RS05190	COG4172	Belongs to the ABC transporter superfamily
LO007_RS05225	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO007_RS05235	COG3706	GGDEF domain
LO007_RS05235	COG4251	negative regulation of phosphorylation
LO007_RS05235	COG5001	Diguanylate cyclase
LO007_RS05235	COG2203	Gaf domain
LO007_RS05245	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO007_RS05245	COG1902	pentaerythritol trinitrate reductase activity
LO007_RS05270	COG3209	COG3209 Rhs family protein
LO007_RS05325	COG0531	amino acid
LO007_RS05345	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS05365	COG1113	amino acid transport
LO007_RS05380	COG0697	spore germination
LO007_RS05385	COG2721	sulfolactate sulfo-lyase activity
LO007_RS05390	COG2271	Major facilitator Superfamily
LO007_RS05395	COG4948	Mandelate Racemase Muconate Lactonizing
LO007_RS05405	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS05410	COG2186	Transcriptional regulator
LO007_RS05435	COG1960	acyl-CoA dehydrogenase activity
LO007_RS05445	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS05450	COG1024	Enoyl-CoA hydratase
LO007_RS05455	COG2814	Major facilitator Superfamily
LO007_RS05470	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO007_RS05515	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LO007_RS05520	COG2072	flavoprotein involved in K transport
LO007_RS05525	COG0300	oxidoreductase activity
LO007_RS05535	COG1309	transcriptional regulator
LO007_RS05540	COG1741	Belongs to the pirin family
LO007_RS05555	COG2072	flavoprotein involved in K transport
LO007_RS05565	COG2252	PERMEase
LO007_RS05570	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LO007_RS05575	COG3038	cytochrome b561
LO007_RS05585	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LO007_RS05595	COG0527	aspartate kinase activity
LO007_RS05640	COG3620	sequence-specific DNA binding
LO007_RS05740	COG5410	chromosome segregation
LO007_RS05745	COG3567	Phage-associated protein, HI1409 family
LO007_RS05765	COG3566	protein conserved in bacteria
LO007_RS05845	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LO007_RS05885	COG0582	viral genome integration into host DNA
LO007_RS05895	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LO007_RS05905	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LO007_RS05920	COG0667	Aldo Keto reductase
LO007_RS05935	COG1765	OsmC-like protein
LO007_RS05950	COG0542	response to heat
LO007_RS05985	COG2885	chlorophyll binding
LO007_RS05995	COG0625	glutathione transferase activity
LO007_RS06000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LO007_RS06020	COG3634	alkyl hydroperoxide reductase activity
LO007_RS06030	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO007_RS06040	COG0450	alkyl hydroperoxide reductase
LO007_RS06045	COG1643	Atp-dependent helicase
LO007_RS06060	COG2814	Major facilitator Superfamily
LO007_RS06065	COG3135	benzoate transporter
LO007_RS06070	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS06075	COG0543	2 iron, 2 sulfur cluster binding
LO007_RS06075	COG0633	Ferredoxin
LO007_RS06080	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LO007_RS06085	COG4638	Rieske (2fe-2S)
LO007_RS06095	COG0583	DNA-binding transcription factor activity
LO007_RS06145	COG1570	exodeoxyribonuclease VII activity
LO007_RS06175	COG1280	lysine exporter protein (LysE YggA)
LO007_RS06180	COG1278	Cold shock
LO007_RS06215	COG2814	Major facilitator Superfamily
LO007_RS06280	COG0210	DNA helicase
LO007_RS06290	COG5377	YqaJ viral recombinase family
LO007_RS06510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LO007_RS06520	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LO007_RS06525	COG1137	ATPase activity
LO007_RS06530	COG1538	Outer membrane efflux protein
LO007_RS06560	COG4122	O-methyltransferase activity
LO007_RS06570	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LO007_RS06585	COG1522	sequence-specific DNA binding
LO007_RS06590	COG5006	permease, DMT superfamily
LO007_RS06600	COG1560	Kdo2-lipid A biosynthetic process
LO007_RS06615	COG2814	Major facilitator Superfamily
LO007_RS06635	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO007_RS06695	COG0583	DNA-binding transcription factor activity
LO007_RS06700	COG1914	H( )-stimulated, divalent metal cation uptake system
LO007_RS06720	COG4770	biotin carboxylase activity
LO007_RS06725	COG0038	chloride channel
LO007_RS06730	COG2831	hemolysin activation secretion protein
LO007_RS06735	COG3210	domain, Protein
LO007_RS06755	COG2801	Transposase and inactivated derivatives
LO007_RS06775	COG1063	alcohol dehydrogenase
LO007_RS06790	COG0439	Biotin carboxylase
LO007_RS06795	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO007_RS06800	COG1733	regulation of RNA biosynthetic process
LO007_RS06810	COG0864	Transcriptional regulator
LO007_RS06820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LO007_RS06825	COG1116	anion transmembrane transporter activity
LO007_RS06945	COG0590	tRNA wobble adenosine to inosine editing
LO007_RS06950	COG2807	transmembrane transport
LO007_RS06965	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LO007_RS06975	COG0789	Transcriptional regulator
LO007_RS06985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO007_RS07005	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LO007_RS07030	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS07035	COG0531	amino acid
LO007_RS07040	COG1760	l-serine dehydratase
LO007_RS07045	COG2030	dehydratase
LO007_RS07045	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS07050	COG3396	Phenylacetate-CoA oxygenase
LO007_RS07055	COG3460	Phenylacetate-CoA oxygenase
LO007_RS07060	COG3396	Phenylacetate-CoA oxygenase
LO007_RS07065	COG2151	metal-sulfur cluster biosynthetic enzyme
LO007_RS07070	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO007_RS07075	COG1024	Enoyl-CoA hydratase
LO007_RS07080	COG1024	Enoyl-CoA hydratase
LO007_RS07085	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO007_RS07090	COG0183	Belongs to the thiolase family
LO007_RS07095	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LO007_RS07100	COG3327	negative regulation of DNA-templated transcription, initiation
LO007_RS07110	COG2050	protein possibly involved in aromatic compounds catabolism
LO007_RS07140	COG2207	Transcriptional regulator
LO007_RS07155	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO007_RS07160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO007_RS07165	COG2271	Major facilitator Superfamily
LO007_RS07170	COG0753	catalase activity
LO007_RS07175	COG3038	cytochrome b561
LO007_RS07180	COG0583	DNA-binding transcription factor activity
LO007_RS07190	COG1414	Transcriptional regulator
LO007_RS07195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO007_RS07205	COG1840	ABC-type Fe3 transport system, periplasmic component
LO007_RS07210	COG3842	ATPase activity
LO007_RS07225	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LO007_RS07230	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO007_RS07235	COG2814	Major facilitator Superfamily
LO007_RS07240	COG1960	acyl-CoA dehydrogenase activity
LO007_RS07255	COG1024	Enoyl-CoA hydratase
LO007_RS07265	COG2814	Major facilitator Superfamily
LO007_RS07275	COG0183	Belongs to the thiolase family
LO007_RS07280	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO007_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS07290	COG1024	Enoyl-CoA hydratase
LO007_RS07295	COG1960	acyl-CoA dehydrogenase activity
LO007_RS07300	COG2814	Major facilitator Superfamily
LO007_RS07305	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LO007_RS07310	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LO007_RS07320	COG2814	Major facilitator Superfamily
LO007_RS07330	COG1960	acyl-CoA dehydrogenase activity
LO007_RS07345	COG0583	DNA-binding transcription factor activity
LO007_RS07355	COG4770	biotin carboxylase activity
LO007_RS07360	COG1024	Enoyl-CoA hydratase
LO007_RS07365	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LO007_RS07370	COG1960	acyl-CoA dehydrogenase activity
LO007_RS07375	COG1309	transcriptional regulator
LO007_RS07380	COG0318	PFAM AMP-dependent synthetase and ligase
LO007_RS07400	COG0583	DNA-binding transcription factor activity
LO007_RS07450	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS07470	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LO007_RS07490	COG2205	protein histidine kinase activity
LO007_RS07490	COG0784	Response regulator, receiver
LO007_RS07510	COG0765	amino acid transport
LO007_RS07515	COG0765	amino acid transport
LO007_RS07520	COG1126	abc transporter atp-binding protein
LO007_RS07525	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LO007_RS07530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LO007_RS07545	COG1280	lysine exporter protein (LysE YggA)
LO007_RS07555	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LO007_RS07560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO007_RS07565	COG1045	serine acetyltransferase
LO007_RS07580	COG0583	DNA-binding transcription factor activity
LO007_RS07585	COG0625	glutathione transferase activity
LO007_RS07590	COG0625	glutathione transferase activity
LO007_RS07595	COG0583	DNA-binding transcription factor activity
LO007_RS07605	COG1346	cytolysis
LO007_RS07625	COG2814	Major facilitator Superfamily
LO007_RS07635	COG0583	DNA-binding transcription factor activity
LO007_RS07645	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LO007_RS07650	COG3052	prosthetic group binding
LO007_RS07670	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LO007_RS07690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO007_RS07700	COG1294	oxidase, subunit
LO007_RS07705	COG1271	oxidase subunit
LO007_RS07735	COG4521	taurine ABC transporter
LO007_RS07740	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LO007_RS07745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO007_RS07750	COG2175	clavaminate synthase activity
LO007_RS07760	COG1953	Uracil, thiamine, allantoin
LO007_RS07770	COG0583	DNA-binding transcription factor activity
LO007_RS07780	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LO007_RS07795	COG0640	Transcriptional regulator
LO007_RS07800	COG0798	PFAM Bile acid sodium symporter
LO007_RS07805	COG0583	DNA-binding transcription factor activity
LO007_RS07820	COG3634	alkyl hydroperoxide reductase activity
LO007_RS07860	COG0436	Aminotransferase
LO007_RS07870	COG0386	Belongs to the glutathione peroxidase family
LO007_RS07910	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LO007_RS07935	COG0012	GTP binding
LO007_RS07940	COG2011	ABC-type metal ion transport system permease component
LO007_RS07945	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LO007_RS07955	COG1464	Belongs to the NlpA lipoprotein family
LO007_RS07985	COG0765	amino acid transport
LO007_RS07990	COG0765	amino acid transport
LO007_RS07995	COG1126	abc transporter atp-binding protein
LO007_RS08005	COG1522	sequence-specific DNA binding
LO007_RS08020	COG1309	transcriptional regulator
LO007_RS08040	COG0583	DNA-binding transcription factor activity
LO007_RS08050	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LO007_RS08060	COG0697	spore germination
LO007_RS08085	COG3121	Chaperone
LO007_RS08090	COG3539	Fimbrial protein
LO007_RS08115	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LO007_RS08115	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LO007_RS08160	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LO007_RS08170	COG2353	YceI-like domain
LO007_RS08180	COG3698	Phosphodiester glycosidase
LO007_RS08195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LO007_RS08200	COG0506	proline dehydrogenase activity
LO007_RS08200	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LO007_RS08200	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LO007_RS08210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LO007_RS08215	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LO007_RS08235	COG1132	(ABC) transporter
LO007_RS08240	COG3122	Protein conserved in bacteria
LO007_RS08245	COG3619	membrane
LO007_RS08255	COG0640	Transcriptional regulator
LO007_RS08265	COG2850	peptidyl-arginine hydroxylation
LO007_RS08270	COG0424	maF-like protein
LO007_RS08290	COG0191	fructose-bisphosphate aldolase activity
LO007_RS08295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LO007_RS08310	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LO007_RS08320	COG1192	Involved in chromosome partitioning
LO007_RS08325	COG1475	DNA binding
LO007_RS08330	COG0811	peptide transport
LO007_RS08340	COG1132	(ABC) transporter
LO007_RS08345	COG1663	tetraacyldisaccharide 4'-kinase activity
LO007_RS08365	COG0084	hydrolase, TatD family'
LO007_RS08430	COG0776	regulation of translation
LO007_RS08460	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LO007_RS08465	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LO007_RS08510	COG0339	signal peptide processing
LO007_RS08515	COG0601	transmembrane transport
LO007_RS08520	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO007_RS08555	COG0702	epimerase
LO007_RS08560	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LO007_RS08580	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LO007_RS08610	COG0316	Belongs to the HesB IscA family
LO007_RS08615	COG0822	iron-sulfur transferase activity
LO007_RS08640	COG0776	regulation of translation
LO007_RS08645	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LO007_RS08650	COG2207	Transcriptional regulator
LO007_RS08655	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LO007_RS08660	COG1960	acyl-CoA dehydrogenase activity
LO007_RS08665	COG1960	acyl-CoA dehydrogenase activity
LO007_RS08680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LO007_RS08695	COG2814	Major facilitator Superfamily
LO007_RS08700	COG4264	IucA IucC family
LO007_RS08705	COG4264	IucA IucC family
LO007_RS08715	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LO007_RS08745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO007_RS08760	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LO007_RS08765	COG0406	alpha-ribazole phosphatase activity
LO007_RS08780	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LO007_RS08785	COG0730	response to heat
LO007_RS08805	COG4773	Receptor
LO007_RS08810	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LO007_RS08825	COG1131	(ABC) transporter
LO007_RS08830	COG0842	Transport permease protein
LO007_RS08835	COG0842	Transport permease protein
LO007_RS08890	COG2226	methyltransferase
LO007_RS08915	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LO007_RS08950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LO007_RS08960	COG0133	tryptophan synthase activity
LO007_RS08975	COG3706	GGDEF domain
LO007_RS08990	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LO007_RS08995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LO007_RS09000	COG0022	dehydrogenase e1 component
LO007_RS09005	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO007_RS09010	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO007_RS09020	COG1063	alcohol dehydrogenase
LO007_RS09025	COG3781	membrane
LO007_RS09035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO007_RS09035	COG3453	Protein conserved in bacteria
LO007_RS09050	COG0730	response to heat
LO007_RS09065	COG2207	Transcriptional regulator
LO007_RS09065	COG3708	Transcriptional regulator
LO007_RS09070	COG1733	regulation of RNA biosynthetic process
LO007_RS09075	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LO007_RS09085	COG2188	Transcriptional regulator
LO007_RS09100	COG4521	taurine ABC transporter
LO007_RS09105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO007_RS09125	COG0477	Major facilitator Superfamily
LO007_RS09135	COG1027	Aspartate ammonia-lyase
LO007_RS09150	COG0583	DNA-binding transcription factor activity
LO007_RS09155	COG0583	DNA-binding transcription factor activity
LO007_RS09160	COG0183	Belongs to the thiolase family
LO007_RS09165	COG2031	fatty acid transporter
LO007_RS09180	COG0583	DNA-binding transcription factor activity
LO007_RS09200	COG1309	transcriptional regulator
LO007_RS09210	COG2610	gluconate transmembrane transporter activity
LO007_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS09225	COG2207	Transcriptional regulator
LO007_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS09250	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO007_RS09265	COG0543	2 iron, 2 sulfur cluster binding
LO007_RS09265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO007_RS09270	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LO007_RS09275	COG4638	Rieske (2fe-2S)
LO007_RS09285	COG0725	ABC transporter, periplasmic molybdate-binding protein
LO007_RS09290	COG4149	molybdate abc transporter
LO007_RS09295	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LO007_RS09300	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS09305	COG3433	isochorismatase activity
LO007_RS09305	COG1535	isochorismatase
LO007_RS09365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LO007_RS09380	COG0753	catalase activity
LO007_RS09390	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LO007_RS09415	COG3539	Fimbrial protein
LO007_RS09430	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LO007_RS09435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO007_RS09440	COG0745	RESPONSE REGULATOR receiver
LO007_RS09445	COG2205	protein histidine kinase activity
LO007_RS09455	COG2207	Transcriptional regulator
LO007_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS09520	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LO007_RS09575	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LO007_RS09595	COG1120	ATPase activity
LO007_RS09600	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO007_RS09610	COG1064	alcohol dehydrogenase
LO007_RS09625	COG2207	Transcriptional regulator
LO007_RS09630	COG2084	Dehydrogenase
LO007_RS09640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LO007_RS09645	COG0583	DNA-binding transcription factor activity
LO007_RS09655	COG0129	dihydroxy-acid dehydratase activity
LO007_RS09660	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS09710	COG0583	DNA-binding transcription factor activity
LO007_RS09725	COG2188	Transcriptional regulator
LO007_RS09755	COG3210	domain, Protein
LO007_RS09760	COG2831	hemolysin activation secretion protein
LO007_RS09770	COG1473	amidohydrolase
LO007_RS09780	COG0475	glutathione-regulated potassium exporter activity
LO007_RS09780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LO007_RS09790	COG0583	DNA-binding transcription factor activity
LO007_RS09795	COG1335	isochorismatase
LO007_RS09805	COG1309	transcriptional regulator
LO007_RS09845	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO007_RS09845	COG1902	pentaerythritol trinitrate reductase activity
LO007_RS09860	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS09885	COG2186	Transcriptional regulator
LO007_RS09895	COG0583	DNA-binding transcription factor activity
LO007_RS09900	COG4948	Mandelate Racemase Muconate Lactonizing
LO007_RS09905	COG4829	muconolactone delta-isomerase
LO007_RS09915	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LO007_RS09920	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LO007_RS09925	COG0183	Belongs to the thiolase family
LO007_RS09930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO007_RS09940	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS09950	COG3733	amine oxidase
LO007_RS09960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO007_RS09970	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS09980	COG4638	Rieske (2fe-2S)
LO007_RS10000	COG0154	amidase activity
LO007_RS10010	COG2814	Major facilitator Superfamily
LO007_RS10035	COG1960	acyl-CoA dehydrogenase activity
LO007_RS10040	COG0583	DNA-binding transcription factor activity
LO007_RS10045	COG1414	Transcriptional regulator
LO007_RS10060	COG2391	methyltransferase activity
LO007_RS10075	COG3659	wide pore channel activity
LO007_RS10080	COG3420	alginic acid biosynthetic process
LO007_RS10085	COG0710	3-dehydroquinate dehydratase activity
LO007_RS10090	COG3485	protocatechuate 3,4-dioxygenase
LO007_RS10095	COG3485	protocatechuate 3,4-dioxygenase
LO007_RS10100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LO007_RS10105	COG2271	Major facilitator Superfamily
LO007_RS10110	COG0596	Alpha beta hydrolase
LO007_RS10115	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LO007_RS10120	COG0183	Belongs to the thiolase family
LO007_RS10125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LO007_RS10130	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LO007_RS10140	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LO007_RS10145	COG2323	membrane
LO007_RS10190	COG1902	pentaerythritol trinitrate reductase activity
LO007_RS10190	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO007_RS10215	COG0542	response to heat
LO007_RS10220	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LO007_RS10250	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LO007_RS10255	COG0569	domain protein
LO007_RS10260	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LO007_RS10280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LO007_RS10290	COG1585	Membrane protein implicated in regulation of membrane protease activity
LO007_RS10305	COG1294	oxidase, subunit
LO007_RS10310	COG4890	Cyd operon protein YbgT
LO007_RS10325	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LO007_RS10335	COG0552	protein localization to endoplasmic reticulum
LO007_RS10360	COG0517	IMP dehydrogenase activity
LO007_RS10360	COG0516	GMP reductase activity
LO007_RS10365	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LO007_RS10370	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LO007_RS10380	COG0583	DNA-binding transcription factor activity
LO007_RS10385	COG0024	Methionine aminopeptidase
LO007_RS10415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LO007_RS10415	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LO007_RS10420	COG1105	Belongs to the carbohydrate kinase PfkB family
LO007_RS10425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LO007_RS10425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LO007_RS10425	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LO007_RS10440	COG3300	MHYT domain
LO007_RS10440	COG5001	Diguanylate cyclase
LO007_RS10455	COG2135	peptidase activity
LO007_RS10460	COG0659	secondary active sulfate transmembrane transporter activity
LO007_RS10480	COG1113	amino acid transport
LO007_RS10490	COG1522	sequence-specific DNA binding
LO007_RS10515	COG1011	Hydrolase
LO007_RS10520	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LO007_RS10530	COG2137	regulation of response to DNA damage stimulus
LO007_RS10545	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LO007_RS10565	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO007_RS10580	COG0575	Belongs to the CDS family
LO007_RS10585	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LO007_RS10605	COG3852	Histidine kinase
LO007_RS10610	COG2204	response regulator
LO007_RS10665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LO007_RS10670	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LO007_RS10690	COG0697	spore germination
LO007_RS10695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO007_RS10705	COG0303	'Molybdopterin
LO007_RS10710	COG0315	cyclic pyranopterin monophosphate synthase activity
LO007_RS10710	COG0521	Mo-molybdopterin cofactor biosynthetic process
LO007_RS10725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LO007_RS10730	COG0243	molybdopterin cofactor binding
LO007_RS10740	COG0243	molybdopterin cofactor binding
LO007_RS10745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO007_RS10750	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO007_RS10750	COG2146	nitrite reductase [NAD(P)H] activity
LO007_RS10760	COG0745	RESPONSE REGULATOR receiver
LO007_RS10765	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO007_RS10765	COG1116	anion transmembrane transporter activity
LO007_RS10780	COG0511	ligase activity, forming carbon-carbon bonds
LO007_RS10795	COG2814	Major facilitator Superfamily
LO007_RS10820	COG0069	glutamate synthase activity
LO007_RS10840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LO007_RS10850	COG1454	alcohol dehydrogenase
LO007_RS10855	COG0824	Thioesterase
LO007_RS10865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LO007_RS10890	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LO007_RS10895	COG2030	dehydratase
LO007_RS10905	COG0183	Belongs to the thiolase family
LO007_RS10915	COG0583	DNA-binding transcription factor activity
LO007_RS10920	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LO007_RS10930	COG1522	sequence-specific DNA binding
LO007_RS10935	COG3135	benzoate transporter
LO007_RS10945	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LO007_RS10970	COG0589	response to stress
LO007_RS10975	COG0488	(ABC) transporter
LO007_RS10995	COG4773	Receptor
LO007_RS11030	COG0668	transmembrane transport
LO007_RS11040	COG1309	transcriptional regulator
LO007_RS11060	COG1605	Chorismate mutase
LO007_RS11100	COG0308	aminopeptidase N
LO007_RS11120	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
LO007_RS11130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LO007_RS11135	COG1454	alcohol dehydrogenase
LO007_RS11155	COG0531	amino acid
LO007_RS11160	COG4303	Ethanolamine ammonia lyase large subunit
LO007_RS11165	COG4302	ethanolamine ammonia-lyase activity
LO007_RS11170	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LO007_RS11170	COG0519	Catalyzes the synthesis of GMP from XMP
LO007_RS11175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LO007_RS11200	COG0697	spore germination
LO007_RS11205	COG1923	regulation of RNA biosynthetic process
LO007_RS11215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LO007_RS11220	COG0802	atpase or kinase
LO007_RS11240	COG1187	pseudouridine synthase activity
LO007_RS11255	COG0583	DNA-binding transcription factor activity
LO007_RS11270	COG2814	Major facilitator Superfamily
LO007_RS11275	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO007_RS11300	COG0729	surface antigen
LO007_RS11320	COG0174	glutamine synthetase
LO007_RS11325	COG0745	RESPONSE REGULATOR receiver
LO007_RS11330	COG2205	protein histidine kinase activity
LO007_RS11335	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
LO007_RS11340	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LO007_RS11345	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LO007_RS11370	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO007_RS11375	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO007_RS11380	COG1960	acyl-CoA dehydrogenase activity
LO007_RS11395	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO007_RS11400	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO007_RS11420	COG0583	DNA-binding transcription factor activity
LO007_RS11435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO007_RS11445	COG3658	cytochrome
LO007_RS11450	COG1215	transferase activity, transferring glycosyl groups
LO007_RS11455	COG1649	PFAM Uncharacterised BCR, COG1649
LO007_RS11455	COG0726	polysaccharide deacetylase
LO007_RS11480	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LO007_RS11485	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LO007_RS11495	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LO007_RS11520	COG0305	Participates in initiation and elongation during chromosome replication
LO007_RS11525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LO007_RS11535	COG1305	Transglutaminase-like
LO007_RS11545	COG2308	Evidence 4 Homologs of previously reported genes of
LO007_RS11575	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LO007_RS11580	COG0138	bifunctional purine biosynthesis protein purh
LO007_RS11585	COG0151	Belongs to the GarS family
LO007_RS11590	COG1464	Belongs to the NlpA lipoprotein family
LO007_RS11595	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LO007_RS11600	COG2011	ABC-type metal ion transport system permease component
LO007_RS11605	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO007_RS11615	COG1301	dicarboxylic acid transport
LO007_RS11645	COG1794	racemase activity, acting on amino acids and derivatives
LO007_RS11665	COG0745	RESPONSE REGULATOR receiver
LO007_RS11670	COG0642	Histidine kinase
LO007_RS11675	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LO007_RS11685	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LO007_RS11725	COG2351	hydroxyisourate hydrolase activity
LO007_RS11735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LO007_RS11735	COG3008	intermembrane lipid transfer
LO007_RS11740	COG2995	paraquat-inducible protein a
LO007_RS11770	COG0477	Major facilitator Superfamily
LO007_RS11820	COG2186	Transcriptional regulator
LO007_RS11830	COG0786	glutamate:sodium symporter activity
LO007_RS11835	COG3243	poly(R)-hydroxyalkanoic acid synthase
LO007_RS11860	COG3111	PFAM Bacterial OB fold (BOF) protein
LO007_RS11925	COG3210	domain, Protein
LO007_RS11945	COG3210	domain, Protein
LO007_RS11945	COG3210	domain, Protein
LO007_RS11950	COG2831	hemolysin activation secretion protein
LO007_RS12005	COG1610	YqeY-like protein
LO007_RS12010	COG4783	chaperone-mediated protein folding
LO007_RS12035	COG1286	toxin biosynthetic process
LO007_RS12355	COG0778	Nitroreductase
LO007_RS12365	COG0513	Belongs to the DEAD box helicase family
LO007_RS12390	COG2363	Small membrane protein
LO007_RS12420	COG1234	tRNA 3'-trailer cleavage
LO007_RS12425	COG2195	Cleaves the N-terminal amino acid of tripeptides
LO007_RS12435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LO007_RS12445	COG2819	hydrolase of the alpha beta superfamily
LO007_RS12450	COG1960	acyl-CoA dehydrogenase activity
LO007_RS12455	COG1301	dicarboxylic acid transport
LO007_RS12460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LO007_RS12465	COG3139	Protein of unknown function (DUF1315)
LO007_RS12470	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LO007_RS12475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LO007_RS12485	COG0494	nUDIX hydrolase
LO007_RS12495	COG0642	Histidine kinase
LO007_RS12505	COG3111	PFAM Bacterial OB fold (BOF) protein
LO007_RS12510	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LO007_RS12520	COG1720	tRNA m6t6A37 methyltransferase activity
LO007_RS12535	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO007_RS12540	COG0826	peptidase U32
LO007_RS12545	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO007_RS12560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO007_RS12605	COG1131	(ABC) transporter
LO007_RS12610	COG0842	Transport permease protein
LO007_RS12625	COG0772	Belongs to the SEDS family
LO007_RS12630	COG2951	lytic endotransglycosylase activity
LO007_RS12655	COG2207	Transcriptional regulator
LO007_RS12670	COG0052	Belongs to the universal ribosomal protein uS2 family
LO007_RS12675	COG0024	Methionine aminopeptidase
LO007_RS12685	COG2223	nitrite transmembrane transporter activity
LO007_RS12695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO007_RS12700	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LO007_RS12705	COG1960	acyl-CoA dehydrogenase activity
LO007_RS12720	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LO007_RS12725	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LO007_RS12730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LO007_RS12750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO007_RS12755	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LO007_RS12760	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LO007_RS12795	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LO007_RS12805	COG0174	glutamine synthetase
LO007_RS12820	COG0512	Glutamine amidotransferase of anthranilate synthase
LO007_RS12825	COG0308	aminopeptidase N
LO007_RS12855	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LO007_RS12865	COG0302	gtp cyclohydrolase
LO007_RS12885	COG3739	integral membrane protein
LO007_RS12900	COG1169	isochorismate synthase
LO007_RS12910	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LO007_RS12915	COG1132	(ABC) transporter
LO007_RS12920	COG1132	(ABC) transporter
LO007_RS12935	COG1535	isochorismatase
LO007_RS12935	COG3433	isochorismatase activity
LO007_RS12940	COG1021	2,3-dihydroxybenzoate-AMP ligase
LO007_RS12945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO007_RS12955	COG4774	siderophore transport
LO007_RS12960	COG4607	ABC-type enterochelin transport system periplasmic component
LO007_RS12965	COG4604	ABC transporter, ATP-binding protein
LO007_RS12970	COG4605	iron ion homeostasis
LO007_RS12975	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO007_RS12980	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO007_RS12995	COG2964	Protein conserved in bacteria
LO007_RS13005	COG1741	Belongs to the pirin family
LO007_RS13040	COG2879	small protein
LO007_RS13045	COG1966	Carbon starvation protein
LO007_RS13065	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LO007_RS13090	COG1067	ATP-dependent peptidase activity
LO007_RS13095	COG0583	DNA-binding transcription factor activity
LO007_RS13120	COG1686	Belongs to the peptidase S11 family
LO007_RS13125	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LO007_RS13160	COG0616	signal peptide processing
LO007_RS13165	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LO007_RS13175	COG0573	inorganic phosphate transmembrane transporter activity
LO007_RS13180	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LO007_RS13185	COG1113	amino acid transport
LO007_RS13190	COG3961	Belongs to the TPP enzyme family
LO007_RS13195	COG1522	sequence-specific DNA binding
LO007_RS13205	COG0076	glutamate decarboxylase activity
LO007_RS13210	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LO007_RS13235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO007_RS13270	COG0352	thiamine-phosphate diphosphorylase activity
LO007_RS13295	COG0612	Peptidase, M16
LO007_RS13305	COG1823	symporter activity
LO007_RS13310	COG0583	DNA-binding transcription factor activity
LO007_RS13315	COG0477	Major facilitator Superfamily
LO007_RS13340	COG1187	pseudouridine synthase activity
LO007_RS13355	COG1686	Belongs to the peptidase S11 family
LO007_RS13360	COG1252	NADH dehydrogenase
LO007_RS13370	COG0415	Belongs to the DNA photolyase family
LO007_RS13385	COG1215	transferase activity, transferring glycosyl groups
LO007_RS13415	COG2070	2-Nitropropane dioxygenase
LO007_RS13470	COG0556	nucleotide-excision repair
LO007_RS13490	COG0436	Aminotransferase
LO007_RS13520	COG4221	oxidoreductase activity
LO007_RS13530	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LO007_RS13535	COG1381	Involved in DNA repair and RecF pathway recombination
LO007_RS13545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LO007_RS13560	COG0681	Belongs to the peptidase S26 family
LO007_RS13570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LO007_RS13580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO007_RS13600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LO007_RS13605	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LO007_RS13610	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LO007_RS13620	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LO007_RS13625	COG4208	sulfate ABC transporter
LO007_RS13630	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LO007_RS13635	COG0583	DNA-binding transcription factor activity
LO007_RS13640	COG4625	pathogenesis
LO007_RS13655	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LO007_RS13670	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LO007_RS13680	COG1051	belongs to the nudix hydrolase family
LO007_RS13680	COG1056	cytidyltransferase-related domain
LO007_RS13685	COG1024	Enoyl-CoA hydratase
LO007_RS13700	COG2814	Major facilitator Superfamily
LO007_RS13705	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LO007_RS13705	COG0047	phosphoribosylformylglycinamidine synthase activity
LO007_RS13725	COG1473	amidohydrolase
LO007_RS13730	COG0824	Thioesterase
LO007_RS13750	COG0823	Involved in the tonB-independent uptake of proteins
LO007_RS13770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LO007_RS13805	COG0628	permease
LO007_RS13815	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LO007_RS13820	COG0596	Alpha beta hydrolase
LO007_RS13825	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LO007_RS13825	COG0616	signal peptide processing
LO007_RS13835	COG0658	competence protein
LO007_RS13835	COG2333	competence protein COMEC
LO007_RS13840	COG1136	(ABC) transporter
LO007_RS13845	COG4591	ABC-type transport system involved in lipoprotein release permease component
LO007_RS13880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO007_RS13900	COG0463	Glycosyl transferase, family 2
LO007_RS13930	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LO007_RS13935	COG1280	lysine exporter protein (LysE YggA)
LO007_RS13945	COG0019	diaminopimelate decarboxylase activity
LO007_RS13955	COG1113	amino acid transport
LO007_RS13970	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LO007_RS13980	COG3339	Conserved Protein
LO007_RS13985	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LO007_RS13990	COG0243	molybdopterin cofactor binding
LO007_RS13995	COG1929	Belongs to the glycerate kinase type-1 family
LO007_RS14010	COG0778	Nitroreductase
LO007_RS14035	COG2801	Transposase and inactivated derivatives
LO007_RS14055	COG0789	Transcriptional regulator
LO007_RS14070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO007_RS14085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LO007_RS14105	COG0741	lytic transglycosylase activity
LO007_RS14125	COG0584	glycerophosphoryl diester phosphodiesterase
LO007_RS14130	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO007_RS14205	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LO007_RS14210	COG1597	lipid kinase activity
LO007_RS14225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LO007_RS14230	COG0477	Major facilitator Superfamily
LO007_RS14280	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LO007_RS14285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LO007_RS14310	COG0505	Belongs to the CarA family
LO007_RS14330	COG0589	response to stress
LO007_RS14345	COG2843	Capsule synthesis protein
LO007_RS14365	COG2321	neutral zinc metallopeptidase
LO007_RS14370	COG2354	Protein conserved in bacteria
LO007_RS14390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO007_RS14415	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LO007_RS14420	COG1053	succinate dehydrogenase
LO007_RS14425	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LO007_RS14430	COG2009	succinate dehydrogenase
LO007_RS14465	COG2921	Belongs to the UPF0250 family
LO007_RS14470	COG0321	lipoyl(octanoyl) transferase activity
LO007_RS14485	COG0531	amino acid
LO007_RS14495	COG1733	regulation of RNA biosynthetic process
LO007_RS14500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LO007_RS14505	COG1648	precorrin-2 dehydrogenase activity
LO007_RS14505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LO007_RS14520	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LO007_RS14550	COG0671	phosphoesterase, PA-phosphatase related
LO007_RS14555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO007_RS14565	COG1538	Outer membrane efflux protein
LO007_RS14570	COG0393	Putative heavy-metal-binding
LO007_RS14575	COG0393	Putative heavy-metal-binding
LO007_RS14585	COG1028	Short-chain dehydrogenase reductase Sdr
LO007_RS14595	COG0525	valine-tRNA ligase activity
LO007_RS14615	COG0583	DNA-binding transcription factor activity
LO007_RS14620	COG0004	ammonium transporteR
LO007_RS14630	COG0642	Histidine kinase
LO007_RS14635	COG0745	RESPONSE REGULATOR receiver
LO007_RS14640	COG2194	sulfuric ester hydrolase activity
LO007_RS14660	COG1752	Esterase of the alpha-beta hydrolase superfamily
LO007_RS14675	COG2315	Protein conserved in bacteria
LO007_RS14680	COG0142	geranyltranstransferase activity
LO007_RS14685	COG2828	Protein conserved in bacteria
LO007_RS14690	COG1113	amino acid transport
LO007_RS14710	COG2207	Transcriptional regulator
LO007_RS14735	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO007_RS14745	COG0560	Phosphoserine phosphatase
LO007_RS14755	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO007_RS14765	COG1530	ribonuclease E activity
LO007_RS14770	COG0424	maF-like protein
LO007_RS14775	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LO007_RS14780	COG1792	Involved in formation and maintenance of cell shape
LO007_RS14785	COG1077	Cell shape determining protein MreB Mrl
LO007_RS14790	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LO007_RS14800	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LO007_RS14825	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LO007_RS14830	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LO007_RS14835	COG1752	Esterase of the alpha-beta hydrolase superfamily
LO007_RS14840	COG1115	amino acid carrier protein
LO007_RS14860	COG2814	Major facilitator Superfamily
LO007_RS14865	COG1289	transmembrane transporter activity
LO007_RS14875	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LO007_RS14915	COG1376	ErfK ybiS ycfS ynhG family protein
LO007_RS14920	COG2832	Protein of unknown function (DUF454)
LO007_RS14930	COG5510	response to toxic substance
LO007_RS14950	COG0840	transmembrane signaling receptor activity
LO007_RS14990	COG3422	double-strand break repair
LO007_RS14995	COG2824	Alkylphosphonate utilization operon protein PhnA
LO007_RS15000	COG3189	MarR family transcriptional regulator
LO007_RS15010	COG0354	folic acid binding
LO007_RS15015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO007_RS15025	COG0679	Auxin Efflux Carrier
LO007_RS15030	COG1902	pentaerythritol trinitrate reductase activity
LO007_RS15035	COG4772	TonB-dependent receptor
LO007_RS15040	COG2094	Belongs to the DNA glycosylase MPG family
LO007_RS15065	COG1217	gtp-binding protein TYPA
LO007_RS15070	COG2233	PERMEase
LO007_RS15080	COG0833	amino acid
LO007_RS15085	COG1690	Belongs to the RtcB family
LO007_RS15095	COG2885	chlorophyll binding
LO007_RS15095	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LO007_RS15105	COG0183	Belongs to the thiolase family
LO007_RS15125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO007_RS15145	COG2207	Transcriptional regulator
LO007_RS15150	COG0183	Belongs to the thiolase family
LO007_RS15180	COG1272	protein, Hemolysin III
LO007_RS15185	COG0477	Major facilitator Superfamily
LO007_RS15200	COG0450	alkyl hydroperoxide reductase
LO007_RS15220	COG0285	dihydrofolate synthase activity
LO007_RS15265	COG4206	TonB-dependent receptor
LO007_RS15270	COG2096	Adenosyltransferase
LO007_RS15275	COG0584	glycerophosphoryl diester phosphodiesterase
LO007_RS15290	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LO007_RS15295	COG0745	RESPONSE REGULATOR receiver
LO007_RS15300	COG2205	protein histidine kinase activity
LO007_RS15310	COG1960	acyl-CoA dehydrogenase activity
LO007_RS15315	COG1960	acyl-CoA dehydrogenase activity
LO007_RS15360	COG0438	transferase activity, transferring glycosyl groups
LO007_RS15365	COG1216	Glycosyl transferase, family 2
LO007_RS15370	COG0438	transferase activity, transferring glycosyl groups
LO007_RS15390	COG0438	transferase activity, transferring glycosyl groups
LO007_RS15395	COG0726	polysaccharide deacetylase
LO007_RS15410	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LO007_RS15455	COG1862	Preprotein translocase
LO007_RS15465	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LO007_RS15470	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LO007_RS15480	COG3781	membrane
LO007_RS15485	COG0613	PHP domain protein
LO007_RS15495	COG2350	Protein conserved in bacteria
LO007_RS15525	COG1607	acyl-coa hydrolase
LO007_RS15585	COG2199	diguanylate cyclase activity
LO007_RS15595	COG1408	metallophosphoesterase
LO007_RS15600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LO007_RS15610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LO007_RS15630	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LO007_RS15635	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LO007_RS15640	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LO007_RS15650	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LO007_RS15660	COG2969	positive regulation of protein catabolic process
LO007_RS15675	COG1024	Enoyl-CoA hydratase
LO007_RS15680	COG1960	acyl-CoA dehydrogenase activity
LO007_RS15685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LO007_RS15700	COG1309	transcriptional regulator
LO007_RS15705	COG1960	acyl-CoA dehydrogenase activity
LO007_RS15750	COG1183	phosphatidylcholine synthase activity
LO007_RS15755	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LO007_RS15785	COG0739	heme binding
LO007_RS15785	COG0741	lytic transglycosylase activity
LO007_RS15785	COG1196	nuclear chromosome segregation
LO007_RS15795	COG1702	phosphate starvation-inducible protein PhoH
LO007_RS15830	COG1295	ribonuclease BN
LO007_RS15835	COG0697	spore germination
LO007_RS15840	COG2169	Transcriptional regulator
LO007_RS15845	COG0179	Fumarylacetoacetate (FAA) hydrolase
LO007_RS15890	COG0557	exoribonuclease II activity
LO007_RS15895	COG0339	signal peptide processing
LO007_RS15900	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LO007_RS15930	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LO007_RS15935	COG1960	acyl-CoA dehydrogenase activity
LO007_RS16090	COG0626	cystathionine gamma-synthase activity
LO007_RS16095	COG0433	COG0433 Predicted ATPase
LO007_RS16100	COG1017	nitric oxide dioxygenase activity
LO007_RS16100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO007_RS16105	COG1959	2 iron, 2 sulfur cluster binding
LO007_RS16120	COG1301	dicarboxylic acid transport
LO007_RS16125	COG1946	Acyl-CoA thioesterase
LO007_RS16145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LO007_RS16150	COG1040	competence protein
LO007_RS16155	COG0494	nUDIX hydrolase
LO007_RS16165	COG0598	Magnesium transport protein CorA
LO007_RS16175	COG2854	intermembrane phospholipid transfer
LO007_RS16185	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LO007_RS16190	COG1127	ABC transporter
LO007_RS16200	COG0513	Belongs to the DEAD box helicase family
LO007_RS16220	COG0408	coproporphyrinogen oxidase activity
LO007_RS16235	COG1960	acyl-CoA dehydrogenase activity
LO007_RS16245	COG1983	PspC domain protein
LO007_RS16250	COG0517	IMP dehydrogenase activity
LO007_RS16290	COG0583	DNA-binding transcription factor activity
LO007_RS16330	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS16340	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LO007_RS16345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LO007_RS16350	COG0833	amino acid
LO007_RS16380	COG1192	Involved in chromosome partitioning
LO007_RS16385	COG0628	permease
LO007_RS16395	COG1289	transmembrane transporter activity
LO007_RS16410	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO007_RS16415	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LO007_RS16425	COG0277	FAD linked oxidase domain protein
LO007_RS16430	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LO007_RS16455	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LO007_RS16460	COG5380	lipid catabolic process
LO007_RS16480	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LO007_RS16530	COG0194	GDP metabolic process
LO007_RS16545	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LO007_RS16565	COG3307	-O-antigen
LO007_RS16585	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LO007_RS16590	COG1704	LemA family
LO007_RS16600	COG0493	'glutamate synthase
LO007_RS16605	COG0070	glutamate synthase
LO007_RS16605	COG0069	glutamate synthase activity
LO007_RS16605	COG0067	glutamate synthase
LO007_RS16655	COG2226	methyltransferase
LO007_RS16670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LO007_RS16675	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LO007_RS16720	COG0833	amino acid
LO007_RS16785	COG0488	(ABC) transporter
LO007_RS16790	COG2873	o-acetylhomoserine
LO007_RS16795	COG4221	oxidoreductase activity
LO007_RS16800	COG0659	secondary active sulfate transmembrane transporter activity
LO007_RS16825	COG0427	acetyl-CoA hydrolase
LO007_RS16855	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LO007_RS16875	COG1132	(ABC) transporter
LO007_RS16900	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LO007_RS16955	COG0582	viral genome integration into host DNA
LO007_RS16995	COG0305	Participates in initiation and elongation during chromosome replication
LO007_RS17085	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO007_RS17090	COG1733	regulation of RNA biosynthetic process
LO007_RS17130	COG0667	Aldo Keto reductase
LO007_RS17150	COG0583	DNA-binding transcription factor activity
LO007_RS17155	COG2814	Major facilitator Superfamily
LO007_RS17185	COG1335	isochorismatase
LO007_RS17195	COG1012	belongs to the aldehyde dehydrogenase family
LO007_RS17200	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LO007_RS17210	COG1113	amino acid transport
LO007_RS17220	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LO007_RS17235	COG2814	Major facilitator Superfamily
LO007_RS17245	COG0351	phosphomethylpyrimidine kinase
LO007_RS17245	COG0352	thiamine-phosphate diphosphorylase activity
LO007_RS17245	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LO007_RS17265	COG1309	transcriptional regulator
LO007_RS17270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LO007_RS17285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LO007_RS17295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LO007_RS17300	COG3162	membrane
LO007_RS17305	COG0784	Response regulator, receiver
LO007_RS17305	COG2198	Histidine kinase
LO007_RS17305	COG2205	protein histidine kinase activity
LO007_RS17330	COG1522	sequence-specific DNA binding
LO007_RS17335	COG1335	isochorismatase
LO007_RS17340	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO007_RS17350	COG0668	transmembrane transport
LO007_RS17355	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LO007_RS17360	COG1519	Transferase
LO007_RS17365	COG1902	pentaerythritol trinitrate reductase activity
LO007_RS17385	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LO007_RS17410	COG0426	domain, Protein
LO007_RS17410	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO007_RS17415	COG4774	siderophore transport
LO007_RS17420	COG2119	membrane
LO007_RS17430	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO007_RS17440	COG4942	peptidase
LO007_RS17455	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LO007_RS17465	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LO007_RS17485	COG0189	ligase activity
LO007_RS17505	COG0708	Exodeoxyribonuclease III
LO007_RS17510	COG1393	Belongs to the ArsC family
LO007_RS17525	COG3706	GGDEF domain
LO007_RS17560	COG2351	hydroxyisourate hydrolase activity
LO007_RS17565	COG2233	PERMEase
LO007_RS17575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO007_RS17585	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LO007_RS17595	COG3150	esterase
LO007_RS17660	COG2826	transposase and inactivated derivatives, IS30 family
LO007_RS17680	COG0673	inositol 2-dehydrogenase activity
LO007_RS17685	COG1324	tolerance protein
LO007_RS17710	COG2826	transposase and inactivated derivatives, IS30 family
LO007_RS17725	COG2918	glutathione biosynthetic process
LO007_RS17740	COG2733	membrane
LO007_RS17745	COG0436	Aminotransferase
LO007_RS17750	COG0534	Mate efflux family protein
LO007_RS17835	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LO007_RS17840	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LO007_RS17850	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LO007_RS17855	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LO007_RS17860	COG0546	phosphoglycolate phosphatase activity
LO007_RS17870	COG0010	Belongs to the arginase family
LO007_RS17900	COG2188	Transcriptional regulator
LO007_RS17910	COG0523	cobalamin synthesis protein
LO007_RS17920	COG1113	amino acid transport
LO007_RS17930	COG0625	glutathione transferase activity
LO007_RS17950	COG1683	Conserved Protein
LO007_RS17955	COG0534	Mate efflux family protein
LO007_RS17960	COG0385	Bile acid
LO007_RS17965	COG1335	isochorismatase
LO007_RS17970	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO007_RS17990	COG2116	formate transmembrane transporter activity
LO007_RS17995	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LO007_RS18000	COG2133	pyrroloquinoline quinone binding
LO007_RS18005	COG2983	Belongs to the UPF0260 family
LO007_RS18025	COG1194	a g-specific adenine glycosylase
LO007_RS18040	COG2818	Glycosylase
LO007_RS18045	COG1064	alcohol dehydrogenase
LO007_RS18050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO007_RS18065	COG0583	DNA-binding transcription factor activity
LO007_RS18070	COG0656	L-ascorbic acid biosynthetic process
LO007_RS18075	COG2814	Major facilitator Superfamily
LO007_RS18110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO007_RS18125	COG2233	PERMEase
LO007_RS18130	COG0583	DNA-binding transcription factor activity
LO007_RS18165	COG0733	neurotransmitter:sodium symporter activity
LO007_RS18205	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LO007_RS18210	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LO007_RS18250	COG0488	(ABC) transporter
LO007_RS18255	COG0586	Pfam SNARE associated Golgi protein
LO007_RS18265	COG0187	DNA topoisomerase II activity
LO007_RS18275	COG0592	DNA-directed DNA polymerase activity
LO007_RS18330	COG0789	Transcriptional regulator
LO007_RS18350	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
LO007_RS18360	COG0659	secondary active sulfate transmembrane transporter activity
LO007_RS18410	COG1373	ATPase (AAA superfamily
LO007_RS18495	COG2184	nucleotidyltransferase activity
LO007_RS18550	COG1309	transcriptional regulator
LO007_RS18575	COG0633	Ferredoxin
LO007_RS18580	COG2207	Transcriptional regulator
LO007_RS18725	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LO007_RS18775	COG1192	Involved in chromosome partitioning
LO007_RS18790	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LO007_RS18820	COG0739	heme binding
LO007_RS18855	COG2826	transposase and inactivated derivatives, IS30 family
LO007_RS19000	COG0501	Belongs to the peptidase M48B family
LO007_RS19050	COG0589	response to stress
LO007_RS19055	COG0659	secondary active sulfate transmembrane transporter activity
LO007_RS19085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LO007_RS19185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LO007_RS19315	COG0583	DNA-binding transcription factor activity
LO007_RS19330	COG3248	Nucleoside-binding outer membrane protein
LO007_RS19335	COG2233	PERMEase
LO007_RS19345	COG0583	DNA-binding transcription factor activity
LO007_RS19350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO007_RS19355	COG4266	Belongs to the allantoicase family
LO007_RS19370	COG2233	PERMEase
LO007_RS19375	COG2351	hydroxyisourate hydrolase activity
LO007_RS19415	COG0484	heat shock protein binding
LO007_RS19500	COG3853	Toxic anion resistance protein (TelA)
LO007_RS19515	COG1475	DNA binding
LO007_RS19575	COG1525	nuclease
LO007_RS19645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LO007_RS19725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO007_RS19760	COG0741	lytic transglycosylase activity
LO007_RS19790	COG2826	transposase and inactivated derivatives, IS30 family
LO007_RS19800	COG2826	transposase and inactivated derivatives, IS30 family
LO007_RS19830	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LO007_RS19845	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LO007_RS19855	COG1192	Involved in chromosome partitioning
LO007_RS19890	COG2026	Addiction module toxin, RelE StbE family