locus-tag	class	description
LO005_RS00020	COG0592	DNA-directed DNA polymerase activity
LO005_RS00030	COG0187	DNA topoisomerase II activity
LO005_RS00040	COG0586	Pfam SNARE associated Golgi protein
LO005_RS00045	COG0488	(ABC) transporter
LO005_RS00070	COG0596	Alpha beta hydrolase
LO005_RS00075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LO005_RS00080	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LO005_RS00120	COG0733	neurotransmitter:sodium symporter activity
LO005_RS00130	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LO005_RS00155	COG0583	DNA-binding transcription factor activity
LO005_RS00160	COG2233	PERMEase
LO005_RS00175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO005_RS00210	COG2814	Major facilitator Superfamily
LO005_RS00215	COG0656	L-ascorbic acid biosynthetic process
LO005_RS00220	COG0583	DNA-binding transcription factor activity
LO005_RS00235	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO005_RS00240	COG1064	alcohol dehydrogenase
LO005_RS00245	COG2818	Glycosylase
LO005_RS00260	COG1194	a g-specific adenine glycosylase
LO005_RS00280	COG2983	Belongs to the UPF0260 family
LO005_RS00285	COG2133	pyrroloquinoline quinone binding
LO005_RS00290	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LO005_RS00295	COG2116	formate transmembrane transporter activity
LO005_RS00315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO005_RS00320	COG1335	isochorismatase
LO005_RS00325	COG0385	Bile acid
LO005_RS00330	COG0534	Mate efflux family protein
LO005_RS00335	COG1683	Conserved Protein
LO005_RS00355	COG0625	glutathione transferase activity
LO005_RS00365	COG1113	amino acid transport
LO005_RS00375	COG0523	cobalamin synthesis protein
LO005_RS00385	COG2188	Transcriptional regulator
LO005_RS00415	COG0010	Belongs to the arginase family
LO005_RS00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LO005_RS00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LO005_RS00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LO005_RS00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LO005_RS00550	COG0534	Mate efflux family protein
LO005_RS00555	COG0436	Aminotransferase
LO005_RS00560	COG2733	membrane
LO005_RS00575	COG2918	glutathione biosynthetic process
LO005_RS00590	COG1388	LysM domain
LO005_RS00590	COG3409	Peptidoglycan-binding domain 1 protein
LO005_RS00590	COG5632	N-Acetylmuramoyl-L-alanine amidase
LO005_RS00620	COG3150	esterase
LO005_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
LO005_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO005_RS00650	COG2233	PERMEase
LO005_RS00690	COG3706	GGDEF domain
LO005_RS00705	COG1393	Belongs to the ArsC family
LO005_RS00710	COG0708	Exodeoxyribonuclease III
LO005_RS00730	COG0189	ligase activity
LO005_RS00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LO005_RS00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LO005_RS00775	COG4942	peptidase
LO005_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO005_RS00795	COG2119	membrane
LO005_RS00800	COG4774	siderophore transport
LO005_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO005_RS00805	COG0426	domain, Protein
LO005_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LO005_RS00850	COG1902	pentaerythritol trinitrate reductase activity
LO005_RS00855	COG1519	Transferase
LO005_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LO005_RS00865	COG0668	transmembrane transport
LO005_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO005_RS00880	COG1335	isochorismatase
LO005_RS00885	COG1522	sequence-specific DNA binding
LO005_RS00910	COG0784	Response regulator, receiver
LO005_RS00910	COG2198	Histidine kinase
LO005_RS00910	COG2205	protein histidine kinase activity
LO005_RS00915	COG3162	membrane
LO005_RS00920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LO005_RS00930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LO005_RS00945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LO005_RS00950	COG1309	transcriptional regulator
LO005_RS00970	COG0352	thiamine-phosphate diphosphorylase activity
LO005_RS00970	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LO005_RS00970	COG0351	phosphomethylpyrimidine kinase
LO005_RS00980	COG2814	Major facilitator Superfamily
LO005_RS00995	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LO005_RS01005	COG1113	amino acid transport
LO005_RS01015	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LO005_RS01020	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS01030	COG1335	isochorismatase
LO005_RS01060	COG2814	Major facilitator Superfamily
LO005_RS01065	COG0583	DNA-binding transcription factor activity
LO005_RS01085	COG0667	Aldo Keto reductase
LO005_RS01105	COG1733	regulation of RNA biosynthetic process
LO005_RS01110	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO005_RS01120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LO005_RS01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LO005_RS01195	COG2329	Antibiotic biosynthesis monooxygenase
LO005_RS01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LO005_RS01255	COG0427	acetyl-CoA hydrolase
LO005_RS01280	COG0659	secondary active sulfate transmembrane transporter activity
LO005_RS01285	COG4221	oxidoreductase activity
LO005_RS01290	COG2873	o-acetylhomoserine
LO005_RS01295	COG0488	(ABC) transporter
LO005_RS01380	COG0833	amino acid
LO005_RS01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LO005_RS01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LO005_RS01445	COG2226	methyltransferase
LO005_RS01495	COG0069	glutamate synthase activity
LO005_RS01495	COG0070	glutamate synthase
LO005_RS01495	COG0067	glutamate synthase
LO005_RS01500	COG0493	'glutamate synthase
LO005_RS01510	COG1704	LemA family
LO005_RS01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LO005_RS01535	COG3307	-O-antigen
LO005_RS01555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LO005_RS01570	COG0194	GDP metabolic process
LO005_RS01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LO005_RS01640	COG5380	lipid catabolic process
LO005_RS01645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LO005_RS01670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LO005_RS01675	COG0277	FAD linked oxidase domain protein
LO005_RS01685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
LO005_RS01690	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO005_RS01705	COG1289	transmembrane transporter activity
LO005_RS01715	COG0628	permease
LO005_RS01720	COG1192	Involved in chromosome partitioning
LO005_RS01750	COG0833	amino acid
LO005_RS01755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LO005_RS01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LO005_RS01770	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS01810	COG0583	DNA-binding transcription factor activity
LO005_RS01855	COG0517	IMP dehydrogenase activity
LO005_RS01860	COG1983	PspC domain protein
LO005_RS01870	COG1960	acyl-CoA dehydrogenase activity
LO005_RS01885	COG0408	coproporphyrinogen oxidase activity
LO005_RS01905	COG0513	Belongs to the DEAD box helicase family
LO005_RS01915	COG1127	ABC transporter
LO005_RS01920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LO005_RS01930	COG2854	intermembrane phospholipid transfer
LO005_RS01940	COG0598	Magnesium transport protein CorA
LO005_RS01950	COG0494	nUDIX hydrolase
LO005_RS01955	COG1040	competence protein
LO005_RS01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LO005_RS01980	COG1946	Acyl-CoA thioesterase
LO005_RS01985	COG1301	dicarboxylic acid transport
LO005_RS02000	COG1959	2 iron, 2 sulfur cluster binding
LO005_RS02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO005_RS02005	COG1017	nitric oxide dioxygenase activity
LO005_RS02015	COG0433	COG0433 Predicted ATPase
LO005_RS02020	COG0626	cystathionine gamma-synthase activity
LO005_RS02175	COG1960	acyl-CoA dehydrogenase activity
LO005_RS02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LO005_RS02210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LO005_RS02215	COG0339	signal peptide processing
LO005_RS02220	COG0557	exoribonuclease II activity
LO005_RS02265	COG0179	Fumarylacetoacetate (FAA) hydrolase
LO005_RS02275	COG0697	spore germination
LO005_RS02280	COG1295	ribonuclease BN
LO005_RS02315	COG1702	phosphate starvation-inducible protein PhoH
LO005_RS02325	COG0741	lytic transglycosylase activity
LO005_RS02325	COG1196	nuclear chromosome segregation
LO005_RS02325	COG0739	heme binding
LO005_RS02355	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LO005_RS02360	COG1183	phosphatidylcholine synthase activity
LO005_RS02405	COG1960	acyl-CoA dehydrogenase activity
LO005_RS02410	COG1309	transcriptional regulator
LO005_RS02425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LO005_RS02430	COG1960	acyl-CoA dehydrogenase activity
LO005_RS02470	COG2969	positive regulation of protein catabolic process
LO005_RS02480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LO005_RS02495	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LO005_RS02500	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LO005_RS02520	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LO005_RS02530	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LO005_RS02535	COG1408	metallophosphoesterase
LO005_RS02545	COG2199	diguanylate cyclase activity
LO005_RS02605	COG1607	acyl-coa hydrolase
LO005_RS02635	COG2350	Protein conserved in bacteria
LO005_RS02645	COG0613	PHP domain protein
LO005_RS02650	COG3781	membrane
LO005_RS02660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LO005_RS02665	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LO005_RS02675	COG1862	Preprotein translocase
LO005_RS02710	COG2205	protein histidine kinase activity
LO005_RS02715	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LO005_RS02730	COG0726	polysaccharide deacetylase
LO005_RS02750	COG1091	dTDP-4-dehydrorhamnose reductase activity
LO005_RS02765	COG1215	transferase activity, transferring glycosyl groups
LO005_RS02815	COG1960	acyl-CoA dehydrogenase activity
LO005_RS02820	COG1960	acyl-CoA dehydrogenase activity
LO005_RS02830	COG2205	protein histidine kinase activity
LO005_RS02835	COG0745	RESPONSE REGULATOR receiver
LO005_RS02840	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LO005_RS02860	COG2096	Adenosyltransferase
LO005_RS02910	COG0285	dihydrofolate synthase activity
LO005_RS02930	COG0450	alkyl hydroperoxide reductase
LO005_RS02945	COG0477	Major facilitator Superfamily
LO005_RS02950	COG1272	protein, Hemolysin III
LO005_RS02980	COG0183	Belongs to the thiolase family
LO005_RS02985	COG2207	Transcriptional regulator
LO005_RS03005	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO005_RS03025	COG0183	Belongs to the thiolase family
LO005_RS03035	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LO005_RS03035	COG2885	chlorophyll binding
LO005_RS03045	COG1690	Belongs to the RtcB family
LO005_RS03050	COG0833	amino acid
LO005_RS03060	COG2233	PERMEase
LO005_RS03065	COG1217	gtp-binding protein TYPA
LO005_RS03090	COG2094	Belongs to the DNA glycosylase MPG family
LO005_RS03095	COG4772	TonB-dependent receptor
LO005_RS03100	COG1902	pentaerythritol trinitrate reductase activity
LO005_RS03115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO005_RS03120	COG0354	folic acid binding
LO005_RS03130	COG3189	MarR family transcriptional regulator
LO005_RS03135	COG2824	Alkylphosphonate utilization operon protein PhnA
LO005_RS03140	COG3422	double-strand break repair
LO005_RS03180	COG0840	transmembrane signaling receptor activity
LO005_RS03195	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LO005_RS03210	COG5510	response to toxic substance
LO005_RS03220	COG2832	Protein of unknown function (DUF454)
LO005_RS03225	COG1376	ErfK ybiS ycfS ynhG family protein
LO005_RS03265	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LO005_RS03275	COG1289	transmembrane transporter activity
LO005_RS03280	COG2814	Major facilitator Superfamily
LO005_RS03300	COG1115	amino acid carrier protein
LO005_RS03305	COG1752	Esterase of the alpha-beta hydrolase superfamily
LO005_RS03310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LO005_RS03315	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
LO005_RS03320	COG3590	peptidase
LO005_RS03345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LO005_RS03355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LO005_RS03360	COG1077	Cell shape determining protein MreB Mrl
LO005_RS03365	COG1792	Involved in formation and maintenance of cell shape
LO005_RS03370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LO005_RS03375	COG0424	maF-like protein
LO005_RS03380	COG1530	ribonuclease E activity
LO005_RS03390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO005_RS03400	COG0560	Phosphoserine phosphatase
LO005_RS03410	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO005_RS03435	COG2207	Transcriptional regulator
LO005_RS03455	COG1113	amino acid transport
LO005_RS03460	COG2828	Protein conserved in bacteria
LO005_RS03465	COG0142	geranyltranstransferase activity
LO005_RS03470	COG2315	Protein conserved in bacteria
LO005_RS03485	COG1752	Esterase of the alpha-beta hydrolase superfamily
LO005_RS03505	COG2194	sulfuric ester hydrolase activity
LO005_RS03510	COG0745	RESPONSE REGULATOR receiver
LO005_RS03515	COG0642	Histidine kinase
LO005_RS03525	COG3293	Transposase
LO005_RS03530	COG0004	ammonium transporteR
LO005_RS03535	COG0583	DNA-binding transcription factor activity
LO005_RS03555	COG0525	valine-tRNA ligase activity
LO005_RS03565	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS03575	COG0393	Putative heavy-metal-binding
LO005_RS03580	COG0393	Putative heavy-metal-binding
LO005_RS03585	COG1538	Outer membrane efflux protein
LO005_RS03595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO005_RS03600	COG0671	phosphoesterase, PA-phosphatase related
LO005_RS03630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LO005_RS03645	COG1648	precorrin-2 dehydrogenase activity
LO005_RS03645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LO005_RS03650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LO005_RS03655	COG1733	regulation of RNA biosynthetic process
LO005_RS03665	COG0531	amino acid
LO005_RS03680	COG0321	lipoyl(octanoyl) transferase activity
LO005_RS03685	COG2921	Belongs to the UPF0250 family
LO005_RS03720	COG2009	succinate dehydrogenase
LO005_RS03725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LO005_RS03730	COG1053	succinate dehydrogenase
LO005_RS03735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LO005_RS03760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO005_RS03780	COG2354	Protein conserved in bacteria
LO005_RS03785	COG2321	neutral zinc metallopeptidase
LO005_RS03805	COG2843	Capsule synthesis protein
LO005_RS03820	COG0589	response to stress
LO005_RS03830	COG0251	oxidation-reduction process
LO005_RS03850	COG0505	Belongs to the CarA family
LO005_RS03875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LO005_RS03880	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LO005_RS03930	COG0477	Major facilitator Superfamily
LO005_RS03935	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LO005_RS03950	COG1597	lipid kinase activity
LO005_RS03955	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LO005_RS03980	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO005_RS03985	COG0584	glycerophosphoryl diester phosphodiesterase
LO005_RS04005	COG0741	lytic transglycosylase activity
LO005_RS04025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LO005_RS04040	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO005_RS04065	COG3811	Belongs to the UPF0386 family
LO005_RS04085	COG0778	Nitroreductase
LO005_RS04100	COG1929	Belongs to the glycerate kinase type-1 family
LO005_RS04105	COG0243	molybdopterin cofactor binding
LO005_RS04110	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LO005_RS04115	COG3339	Conserved Protein
LO005_RS04125	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
LO005_RS04140	COG1113	amino acid transport
LO005_RS04150	COG0019	diaminopimelate decarboxylase activity
LO005_RS04160	COG1280	lysine exporter protein (LysE YggA)
LO005_RS04165	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LO005_RS04195	COG0463	Glycosyl transferase, family 2
LO005_RS04215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO005_RS04250	COG4591	ABC-type transport system involved in lipoprotein release permease component
LO005_RS04255	COG1136	(ABC) transporter
LO005_RS04260	COG0658	competence protein
LO005_RS04260	COG2333	competence protein COMEC
LO005_RS04270	COG0616	signal peptide processing
LO005_RS04270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LO005_RS04275	COG0596	Alpha beta hydrolase
LO005_RS04280	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LO005_RS04290	COG0628	permease
LO005_RS04325	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LO005_RS04345	COG0823	Involved in the tonB-independent uptake of proteins
LO005_RS04365	COG0824	Thioesterase
LO005_RS04370	COG1473	amidohydrolase
LO005_RS04390	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LO005_RS04390	COG0047	phosphoribosylformylglycinamidine synthase activity
LO005_RS04395	COG2814	Major facilitator Superfamily
LO005_RS04410	COG1024	Enoyl-CoA hydratase
LO005_RS04415	COG1051	belongs to the nudix hydrolase family
LO005_RS04415	COG1056	cytidyltransferase-related domain
LO005_RS04425	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LO005_RS04440	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LO005_RS04455	COG4625	pathogenesis
LO005_RS04460	COG0583	DNA-binding transcription factor activity
LO005_RS04465	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LO005_RS04470	COG4208	sulfate ABC transporter
LO005_RS04475	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LO005_RS04485	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LO005_RS04490	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LO005_RS04495	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LO005_RS04515	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO005_RS04530	COG0681	Belongs to the peptidase S26 family
LO005_RS04545	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LO005_RS04555	COG1381	Involved in DNA repair and RecF pathway recombination
LO005_RS04560	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LO005_RS04570	COG4221	oxidoreductase activity
LO005_RS04600	COG0443	Heat shock 70 kDa protein
LO005_RS04610	COG0436	Aminotransferase
LO005_RS04630	COG0556	nucleotide-excision repair
LO005_RS04685	COG2070	2-Nitropropane dioxygenase
LO005_RS04715	COG1215	transferase activity, transferring glycosyl groups
LO005_RS04730	COG0415	Belongs to the DNA photolyase family
LO005_RS04740	COG1252	NADH dehydrogenase
LO005_RS04745	COG1686	Belongs to the peptidase S11 family
LO005_RS04760	COG1187	pseudouridine synthase activity
LO005_RS04785	COG0477	Major facilitator Superfamily
LO005_RS04790	COG0583	DNA-binding transcription factor activity
LO005_RS04795	COG1823	symporter activity
LO005_RS04805	COG0612	Peptidase, M16
LO005_RS04830	COG0352	thiamine-phosphate diphosphorylase activity
LO005_RS04865	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO005_RS04875	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO005_RS04890	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
LO005_RS04895	COG0076	glutamate decarboxylase activity
LO005_RS04905	COG1522	sequence-specific DNA binding
LO005_RS04910	COG3961	Belongs to the TPP enzyme family
LO005_RS04915	COG1113	amino acid transport
LO005_RS04920	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
LO005_RS04925	COG0573	inorganic phosphate transmembrane transporter activity
LO005_RS04935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LO005_RS04940	COG0616	signal peptide processing
LO005_RS04975	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LO005_RS04980	COG1686	Belongs to the peptidase S11 family
LO005_RS05005	COG0583	DNA-binding transcription factor activity
LO005_RS05010	COG1067	ATP-dependent peptidase activity
LO005_RS05035	COG4943	cyclic-guanylate-specific phosphodiesterase activity
LO005_RS05055	COG1966	Carbon starvation protein
LO005_RS05060	COG2879	small protein
LO005_RS05070	COG2130	NADP-dependent
LO005_RS05095	COG1741	Belongs to the pirin family
LO005_RS05105	COG2964	Protein conserved in bacteria
LO005_RS05120	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO005_RS05130	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LO005_RS05135	COG4605	iron ion homeostasis
LO005_RS05140	COG4604	ABC transporter, ATP-binding protein
LO005_RS05145	COG4607	ABC-type enterochelin transport system periplasmic component
LO005_RS05150	COG4774	siderophore transport
LO005_RS05160	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LO005_RS05165	COG1021	2,3-dihydroxybenzoate-AMP ligase
LO005_RS05170	COG1535	isochorismatase
LO005_RS05170	COG3433	isochorismatase activity
LO005_RS05185	COG1132	(ABC) transporter
LO005_RS05190	COG1132	(ABC) transporter
LO005_RS05195	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
LO005_RS05200	COG2977	Belongs to the P-Pant transferase superfamily
LO005_RS05205	COG1169	isochorismate synthase
LO005_RS05220	COG3739	integral membrane protein
LO005_RS05240	COG0302	gtp cyclohydrolase
LO005_RS05250	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LO005_RS05280	COG0308	aminopeptidase N
LO005_RS05285	COG0512	Glutamine amidotransferase of anthranilate synthase
LO005_RS05435	COG5410	chromosome segregation
LO005_RS05530	COG0739	heme binding
LO005_RS05580	COG1063	alcohol dehydrogenase
LO005_RS05585	COG3293	Transposase
LO005_RS05610	COG0582	viral genome integration into host DNA
LO005_RS05620	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LO005_RS05635	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LO005_RS05650	COG0667	Aldo Keto reductase
LO005_RS05665	COG1765	OsmC-like protein
LO005_RS05680	COG0542	response to heat
LO005_RS05715	COG2885	chlorophyll binding
LO005_RS05725	COG0625	glutathione transferase activity
LO005_RS05730	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LO005_RS05750	COG3634	alkyl hydroperoxide reductase activity
LO005_RS05760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LO005_RS05770	COG0450	alkyl hydroperoxide reductase
LO005_RS05775	COG1643	Atp-dependent helicase
LO005_RS05790	COG2814	Major facilitator Superfamily
LO005_RS05795	COG3135	benzoate transporter
LO005_RS05800	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS05805	COG0543	2 iron, 2 sulfur cluster binding
LO005_RS05805	COG0633	Ferredoxin
LO005_RS05815	COG4638	Rieske (2fe-2S)
LO005_RS05825	COG0583	DNA-binding transcription factor activity
LO005_RS05835	COG2871	sodium ion transport
LO005_RS05920	COG1570	exodeoxyribonuclease VII activity
LO005_RS05950	COG1280	lysine exporter protein (LysE YggA)
LO005_RS05955	COG1278	Cold shock
LO005_RS05990	COG2814	Major facilitator Superfamily
LO005_RS06030	COG0517	IMP dehydrogenase activity
LO005_RS06030	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LO005_RS06035	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LO005_RS06045	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LO005_RS06050	COG1137	ATPase activity
LO005_RS06055	COG1538	Outer membrane efflux protein
LO005_RS06085	COG4122	O-methyltransferase activity
LO005_RS06095	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LO005_RS06110	COG1522	sequence-specific DNA binding
LO005_RS06125	COG1560	Kdo2-lipid A biosynthetic process
LO005_RS06130	COG0598	Magnesium transport protein CorA
LO005_RS06150	COG2814	Major facilitator Superfamily
LO005_RS06170	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO005_RS06190	COG1011	Hydrolase
LO005_RS06240	COG0583	DNA-binding transcription factor activity
LO005_RS06245	COG1914	H( )-stimulated, divalent metal cation uptake system
LO005_RS06265	COG4770	biotin carboxylase activity
LO005_RS06270	COG0038	chloride channel
LO005_RS06285	COG1309	transcriptional regulator
LO005_RS06295	COG1063	alcohol dehydrogenase
LO005_RS06310	COG0439	Biotin carboxylase
LO005_RS06315	COG2249	NAD(P)H dehydrogenase (quinone) activity
LO005_RS06320	COG1733	regulation of RNA biosynthetic process
LO005_RS06330	COG0864	Transcriptional regulator
LO005_RS06340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LO005_RS06345	COG1116	anion transmembrane transporter activity
LO005_RS06465	COG0590	tRNA wobble adenosine to inosine editing
LO005_RS06470	COG2807	transmembrane transport
LO005_RS06485	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
LO005_RS06495	COG0789	Transcriptional regulator
LO005_RS06505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO005_RS06525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LO005_RS06550	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS06555	COG0531	amino acid
LO005_RS06560	COG1760	l-serine dehydratase
LO005_RS06565	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS06565	COG2030	dehydratase
LO005_RS06570	COG3396	Phenylacetate-CoA oxygenase
LO005_RS06575	COG3460	Phenylacetate-CoA oxygenase
LO005_RS06580	COG3396	Phenylacetate-CoA oxygenase
LO005_RS06585	COG2151	metal-sulfur cluster biosynthetic enzyme
LO005_RS06590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO005_RS06595	COG1024	Enoyl-CoA hydratase
LO005_RS06600	COG1024	Enoyl-CoA hydratase
LO005_RS06605	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO005_RS06610	COG0183	Belongs to the thiolase family
LO005_RS06615	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
LO005_RS06620	COG3327	negative regulation of DNA-templated transcription, initiation
LO005_RS06630	COG2050	protein possibly involved in aromatic compounds catabolism
LO005_RS06655	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO005_RS06660	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO005_RS06665	COG2271	Major facilitator Superfamily
LO005_RS06675	COG0753	catalase activity
LO005_RS06680	COG3038	cytochrome b561
LO005_RS06700	COG2267	carboxylic ester hydrolase activity
LO005_RS06705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO005_RS06710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO005_RS06715	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS06725	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LO005_RS06735	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS06740	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LO005_RS06745	COG0583	DNA-binding transcription factor activity
LO005_RS06755	COG1414	Transcriptional regulator
LO005_RS06760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO005_RS06775	COG1840	ABC-type Fe3 transport system, periplasmic component
LO005_RS06780	COG3842	ATPase activity
LO005_RS06795	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LO005_RS06800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO005_RS06805	COG2814	Major facilitator Superfamily
LO005_RS06810	COG1960	acyl-CoA dehydrogenase activity
LO005_RS06825	COG1024	Enoyl-CoA hydratase
LO005_RS06835	COG2814	Major facilitator Superfamily
LO005_RS06845	COG0183	Belongs to the thiolase family
LO005_RS06850	COG1250	3-hydroxyacyl-CoA dehydrogenase
LO005_RS06855	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS06860	COG1024	Enoyl-CoA hydratase
LO005_RS06865	COG1960	acyl-CoA dehydrogenase activity
LO005_RS06870	COG2814	Major facilitator Superfamily
LO005_RS06875	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LO005_RS06880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LO005_RS06890	COG2814	Major facilitator Superfamily
LO005_RS06900	COG1960	acyl-CoA dehydrogenase activity
LO005_RS06915	COG0583	DNA-binding transcription factor activity
LO005_RS06925	COG4770	biotin carboxylase activity
LO005_RS06930	COG1024	Enoyl-CoA hydratase
LO005_RS06935	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LO005_RS06940	COG1960	acyl-CoA dehydrogenase activity
LO005_RS06945	COG1309	transcriptional regulator
LO005_RS06950	COG0318	PFAM AMP-dependent synthetase and ligase
LO005_RS06970	COG0583	DNA-binding transcription factor activity
LO005_RS07020	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS07045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LO005_RS07065	COG0784	Response regulator, receiver
LO005_RS07065	COG2205	protein histidine kinase activity
LO005_RS07085	COG0765	amino acid transport
LO005_RS07090	COG0765	amino acid transport
LO005_RS07100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LO005_RS07105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LO005_RS07120	COG1280	lysine exporter protein (LysE YggA)
LO005_RS07125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LO005_RS07130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO005_RS07135	COG1045	serine acetyltransferase
LO005_RS07150	COG0583	DNA-binding transcription factor activity
LO005_RS07155	COG0625	glutathione transferase activity
LO005_RS07160	COG0625	glutathione transferase activity
LO005_RS07165	COG0583	DNA-binding transcription factor activity
LO005_RS07175	COG1346	cytolysis
LO005_RS07195	COG2814	Major facilitator Superfamily
LO005_RS07205	COG0583	DNA-binding transcription factor activity
LO005_RS07215	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
LO005_RS07220	COG3052	prosthetic group binding
LO005_RS07240	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LO005_RS07260	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO005_RS07270	COG1294	oxidase, subunit
LO005_RS07275	COG1271	oxidase subunit
LO005_RS07295	COG0477	Major facilitator Superfamily
LO005_RS07305	COG4521	taurine ABC transporter
LO005_RS07310	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
LO005_RS07315	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO005_RS07320	COG2175	clavaminate synthase activity
LO005_RS07330	COG1953	Uracil, thiamine, allantoin
LO005_RS07340	COG0583	DNA-binding transcription factor activity
LO005_RS07350	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
LO005_RS07365	COG0640	Transcriptional regulator
LO005_RS07370	COG0798	PFAM Bile acid sodium symporter
LO005_RS07375	COG0583	DNA-binding transcription factor activity
LO005_RS07390	COG3634	alkyl hydroperoxide reductase activity
LO005_RS07430	COG0436	Aminotransferase
LO005_RS07440	COG0386	Belongs to the glutathione peroxidase family
LO005_RS07480	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
LO005_RS07505	COG0012	GTP binding
LO005_RS07510	COG2011	ABC-type metal ion transport system permease component
LO005_RS07515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LO005_RS07525	COG1464	Belongs to the NlpA lipoprotein family
LO005_RS07555	COG0765	amino acid transport
LO005_RS07560	COG0765	amino acid transport
LO005_RS07565	COG1126	abc transporter atp-binding protein
LO005_RS07575	COG1522	sequence-specific DNA binding
LO005_RS07590	COG1309	transcriptional regulator
LO005_RS07610	COG0583	DNA-binding transcription factor activity
LO005_RS07620	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
LO005_RS07630	COG0697	spore germination
LO005_RS07655	COG3121	Chaperone
LO005_RS07660	COG3539	Fimbrial protein
LO005_RS07685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LO005_RS07685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LO005_RS07730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LO005_RS07740	COG2353	YceI-like domain
LO005_RS07750	COG3698	Phosphodiester glycosidase
LO005_RS07765	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
LO005_RS07770	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LO005_RS07770	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
LO005_RS07770	COG0506	proline dehydrogenase activity
LO005_RS07780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LO005_RS07785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LO005_RS07805	COG1132	(ABC) transporter
LO005_RS07810	COG3122	Protein conserved in bacteria
LO005_RS07815	COG3619	membrane
LO005_RS07825	COG0640	Transcriptional regulator
LO005_RS07835	COG2850	peptidyl-arginine hydroxylation
LO005_RS07840	COG0424	maF-like protein
LO005_RS07860	COG0191	fructose-bisphosphate aldolase activity
LO005_RS07865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LO005_RS07880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LO005_RS07890	COG1192	Involved in chromosome partitioning
LO005_RS07895	COG1475	DNA binding
LO005_RS07900	COG0811	peptide transport
LO005_RS07910	COG1132	(ABC) transporter
LO005_RS07915	COG1663	tetraacyldisaccharide 4'-kinase activity
LO005_RS07935	COG0084	hydrolase, TatD family'
LO005_RS08000	COG0776	regulation of translation
LO005_RS08030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LO005_RS08035	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LO005_RS08080	COG0339	signal peptide processing
LO005_RS08090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LO005_RS08125	COG0702	epimerase
LO005_RS08130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LO005_RS08150	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LO005_RS08180	COG0316	Belongs to the HesB IscA family
LO005_RS08185	COG0822	iron-sulfur transferase activity
LO005_RS08210	COG0776	regulation of translation
LO005_RS08215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LO005_RS08220	COG2207	Transcriptional regulator
LO005_RS08225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LO005_RS08230	COG1960	acyl-CoA dehydrogenase activity
LO005_RS08235	COG1960	acyl-CoA dehydrogenase activity
LO005_RS08250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LO005_RS08265	COG2814	Major facilitator Superfamily
LO005_RS08270	COG4264	IucA IucC family
LO005_RS08275	COG4264	IucA IucC family
LO005_RS08285	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LO005_RS08315	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LO005_RS08330	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
LO005_RS08335	COG0406	alpha-ribazole phosphatase activity
LO005_RS08350	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LO005_RS08355	COG0730	response to heat
LO005_RS08375	COG4773	Receptor
LO005_RS08380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LO005_RS08395	COG1131	(ABC) transporter
LO005_RS08400	COG0842	Transport permease protein
LO005_RS08405	COG0842	Transport permease protein
LO005_RS08460	COG2226	methyltransferase
LO005_RS08485	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LO005_RS08520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LO005_RS08530	COG0133	tryptophan synthase activity
LO005_RS08560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LO005_RS08565	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LO005_RS08570	COG0022	dehydrogenase e1 component
LO005_RS08575	COG0508	dehydrogenase complex catalyzes the overall conversion of
LO005_RS08580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO005_RS08590	COG1063	alcohol dehydrogenase
LO005_RS08595	COG3781	membrane
LO005_RS08620	COG0730	response to heat
LO005_RS08635	COG2207	Transcriptional regulator
LO005_RS08635	COG3708	Transcriptional regulator
LO005_RS08640	COG1733	regulation of RNA biosynthetic process
LO005_RS08645	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LO005_RS08655	COG2188	Transcriptional regulator
LO005_RS08670	COG4521	taurine ABC transporter
LO005_RS08675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO005_RS08695	COG0477	Major facilitator Superfamily
LO005_RS08705	COG1027	Aspartate ammonia-lyase
LO005_RS08720	COG0583	DNA-binding transcription factor activity
LO005_RS08725	COG0583	DNA-binding transcription factor activity
LO005_RS08730	COG0183	Belongs to the thiolase family
LO005_RS08735	COG2031	fatty acid transporter
LO005_RS08750	COG0583	DNA-binding transcription factor activity
LO005_RS08780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO005_RS08790	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS08795	COG2207	Transcriptional regulator
LO005_RS08810	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS08820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO005_RS08835	COG0543	2 iron, 2 sulfur cluster binding
LO005_RS08835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO005_RS08840	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
LO005_RS08845	COG4638	Rieske (2fe-2S)
LO005_RS08855	COG0725	ABC transporter, periplasmic molybdate-binding protein
LO005_RS08860	COG4149	molybdate abc transporter
LO005_RS08865	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LO005_RS08870	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS08875	COG3433	isochorismatase activity
LO005_RS08875	COG1535	isochorismatase
LO005_RS08940	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LO005_RS08955	COG0753	catalase activity
LO005_RS08965	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
LO005_RS08990	COG3539	Fimbrial protein
LO005_RS09035	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LO005_RS09040	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO005_RS09045	COG0745	RESPONSE REGULATOR receiver
LO005_RS09050	COG2205	protein histidine kinase activity
LO005_RS09060	COG2207	Transcriptional regulator
LO005_RS09070	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS09075	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS09145	COG2188	Transcriptional regulator
LO005_RS09195	COG0318	PFAM AMP-dependent synthetase and ligase
LO005_RS09205	COG1960	acyl-CoA dehydrogenase activity
LO005_RS09215	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS09220	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS09225	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS09230	COG0583	DNA-binding transcription factor activity
LO005_RS09235	COG1309	transcriptional regulator
LO005_RS09265	COG0789	Transcriptional regulator
LO005_RS09280	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO005_RS09280	COG1902	pentaerythritol trinitrate reductase activity
LO005_RS09295	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS09315	COG2186	Transcriptional regulator
LO005_RS09325	COG0583	DNA-binding transcription factor activity
LO005_RS09330	COG4948	Mandelate Racemase Muconate Lactonizing
LO005_RS09335	COG4829	muconolactone delta-isomerase
LO005_RS09345	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LO005_RS09350	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LO005_RS09355	COG0183	Belongs to the thiolase family
LO005_RS09360	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO005_RS09365	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS09375	COG3733	amine oxidase
LO005_RS09385	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO005_RS09395	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS09405	COG4638	Rieske (2fe-2S)
LO005_RS09425	COG0154	amidase activity
LO005_RS09435	COG2814	Major facilitator Superfamily
LO005_RS09460	COG1960	acyl-CoA dehydrogenase activity
LO005_RS09465	COG0583	DNA-binding transcription factor activity
LO005_RS09470	COG1414	Transcriptional regulator
LO005_RS09485	COG2391	methyltransferase activity
LO005_RS09495	COG4993	Dehydrogenase
LO005_RS09500	COG3659	wide pore channel activity
LO005_RS09505	COG3420	alginic acid biosynthetic process
LO005_RS09510	COG0710	3-dehydroquinate dehydratase activity
LO005_RS09515	COG3485	protocatechuate 3,4-dioxygenase
LO005_RS09520	COG3485	protocatechuate 3,4-dioxygenase
LO005_RS09525	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LO005_RS09530	COG2271	Major facilitator Superfamily
LO005_RS09535	COG0596	Alpha beta hydrolase
LO005_RS09540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LO005_RS09545	COG0183	Belongs to the thiolase family
LO005_RS09550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
LO005_RS09555	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
LO005_RS09565	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LO005_RS09570	COG2323	membrane
LO005_RS09615	COG1902	pentaerythritol trinitrate reductase activity
LO005_RS09615	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO005_RS09640	COG0542	response to heat
LO005_RS09645	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LO005_RS09675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LO005_RS09680	COG0569	domain protein
LO005_RS09685	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LO005_RS09700	COG4774	siderophore transport
LO005_RS09705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LO005_RS09715	COG1585	Membrane protein implicated in regulation of membrane protease activity
LO005_RS09730	COG1294	oxidase, subunit
LO005_RS09735	COG4890	Cyd operon protein YbgT
LO005_RS09745	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LO005_RS09755	COG0552	protein localization to endoplasmic reticulum
LO005_RS09780	COG0516	GMP reductase activity
LO005_RS09780	COG0517	IMP dehydrogenase activity
LO005_RS09785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LO005_RS09790	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LO005_RS09800	COG0583	DNA-binding transcription factor activity
LO005_RS09805	COG0024	Methionine aminopeptidase
LO005_RS09835	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LO005_RS09835	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LO005_RS09840	COG1105	Belongs to the carbohydrate kinase PfkB family
LO005_RS09845	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LO005_RS09845	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LO005_RS09845	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LO005_RS09880	COG2135	peptidase activity
LO005_RS09885	COG0659	secondary active sulfate transmembrane transporter activity
LO005_RS09905	COG1113	amino acid transport
LO005_RS09915	COG1522	sequence-specific DNA binding
LO005_RS09940	COG1011	Hydrolase
LO005_RS09945	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LO005_RS09955	COG2137	regulation of response to DNA damage stimulus
LO005_RS09970	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LO005_RS09990	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO005_RS10005	COG0575	Belongs to the CDS family
LO005_RS10010	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LO005_RS10035	COG3852	Histidine kinase
LO005_RS10040	COG2204	response regulator
LO005_RS10095	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LO005_RS10100	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LO005_RS10120	COG0697	spore germination
LO005_RS10125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO005_RS10135	COG0303	'Molybdopterin
LO005_RS10140	COG0315	cyclic pyranopterin monophosphate synthase activity
LO005_RS10140	COG0521	Mo-molybdopterin cofactor biosynthetic process
LO005_RS10155	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LO005_RS10160	COG0243	molybdopterin cofactor binding
LO005_RS10170	COG0243	molybdopterin cofactor binding
LO005_RS10175	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO005_RS10180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO005_RS10180	COG2146	nitrite reductase [NAD(P)H] activity
LO005_RS10190	COG0745	RESPONSE REGULATOR receiver
LO005_RS10195	COG1116	anion transmembrane transporter activity
LO005_RS10195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO005_RS10215	COG0511	ligase activity, forming carbon-carbon bonds
LO005_RS10230	COG2814	Major facilitator Superfamily
LO005_RS10300	COG0739	heme binding
LO005_RS10300	COG1196	nuclear chromosome segregation
LO005_RS10300	COG0741	lytic transglycosylase activity
LO005_RS10315	COG1598	PFAM Uncharacterised protein family UPF0150
LO005_RS10405	COG5410	chromosome segregation
LO005_RS10605	COG0069	glutamate synthase activity
LO005_RS10635	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LO005_RS10645	COG1454	alcohol dehydrogenase
LO005_RS10650	COG0824	Thioesterase
LO005_RS10660	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LO005_RS10685	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LO005_RS10690	COG2030	dehydratase
LO005_RS10700	COG0183	Belongs to the thiolase family
LO005_RS10710	COG0583	DNA-binding transcription factor activity
LO005_RS10715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LO005_RS10725	COG1522	sequence-specific DNA binding
LO005_RS10730	COG3135	benzoate transporter
LO005_RS10740	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LO005_RS10765	COG0589	response to stress
LO005_RS10770	COG0488	(ABC) transporter
LO005_RS10790	COG4773	Receptor
LO005_RS10815	COG3293	Transposase
LO005_RS10825	COG0668	transmembrane transport
LO005_RS10835	COG1309	transcriptional regulator
LO005_RS10855	COG1605	Chorismate mutase
LO005_RS10895	COG0308	aminopeptidase N
LO005_RS10920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LO005_RS10925	COG1454	alcohol dehydrogenase
LO005_RS10945	COG0531	amino acid
LO005_RS10950	COG4303	Ethanolamine ammonia lyase large subunit
LO005_RS10955	COG4302	ethanolamine ammonia-lyase activity
LO005_RS10960	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LO005_RS10960	COG0519	Catalyzes the synthesis of GMP from XMP
LO005_RS10965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LO005_RS10990	COG0697	spore germination
LO005_RS10995	COG1923	regulation of RNA biosynthetic process
LO005_RS11005	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LO005_RS11010	COG0802	atpase or kinase
LO005_RS11030	COG1187	pseudouridine synthase activity
LO005_RS11045	COG0583	DNA-binding transcription factor activity
LO005_RS11060	COG2814	Major facilitator Superfamily
LO005_RS11065	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LO005_RS11090	COG0729	surface antigen
LO005_RS11110	COG0174	glutamine synthetase
LO005_RS11115	COG0745	RESPONSE REGULATOR receiver
LO005_RS11120	COG2205	protein histidine kinase activity
LO005_RS11130	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
LO005_RS11135	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
LO005_RS11160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO005_RS11165	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO005_RS11170	COG1960	acyl-CoA dehydrogenase activity
LO005_RS11215	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO005_RS11225	COG3658	cytochrome
LO005_RS11230	COG1215	transferase activity, transferring glycosyl groups
LO005_RS11235	COG0726	polysaccharide deacetylase
LO005_RS11235	COG1649	PFAM Uncharacterised BCR, COG1649
LO005_RS11260	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LO005_RS11265	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LO005_RS11275	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LO005_RS11300	COG0305	Participates in initiation and elongation during chromosome replication
LO005_RS11305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LO005_RS11315	COG1305	Transglutaminase-like
LO005_RS11325	COG2308	Evidence 4 Homologs of previously reported genes of
LO005_RS11355	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LO005_RS11360	COG0138	bifunctional purine biosynthesis protein purh
LO005_RS11365	COG0151	Belongs to the GarS family
LO005_RS11370	COG1464	Belongs to the NlpA lipoprotein family
LO005_RS11375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LO005_RS11380	COG2011	ABC-type metal ion transport system permease component
LO005_RS11385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO005_RS11395	COG1301	dicarboxylic acid transport
LO005_RS11425	COG1794	racemase activity, acting on amino acids and derivatives
LO005_RS11445	COG0745	RESPONSE REGULATOR receiver
LO005_RS11450	COG0642	Histidine kinase
LO005_RS11455	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LO005_RS11465	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LO005_RS11505	COG2351	hydroxyisourate hydrolase activity
LO005_RS11515	COG3008	intermembrane lipid transfer
LO005_RS11515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LO005_RS11520	COG2995	paraquat-inducible protein a
LO005_RS11535	COG2985	domain, Protein
LO005_RS11560	COG0477	Major facilitator Superfamily
LO005_RS11610	COG2186	Transcriptional regulator
LO005_RS11620	COG0786	glutamate:sodium symporter activity
LO005_RS11625	COG3243	poly(R)-hydroxyalkanoic acid synthase
LO005_RS11655	COG3111	PFAM Bacterial OB fold (BOF) protein
LO005_RS11740	COG3210	domain, Protein
LO005_RS11740	COG3210	domain, Protein
LO005_RS11745	COG2831	hemolysin activation secretion protein
LO005_RS11800	COG1610	YqeY-like protein
LO005_RS11805	COG4783	chaperone-mediated protein folding
LO005_RS11830	COG1286	toxin biosynthetic process
LO005_RS11860	COG0778	Nitroreductase
LO005_RS11870	COG0513	Belongs to the DEAD box helicase family
LO005_RS11895	COG2363	Small membrane protein
LO005_RS11925	COG1234	tRNA 3'-trailer cleavage
LO005_RS11930	COG2195	Cleaves the N-terminal amino acid of tripeptides
LO005_RS11940	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LO005_RS11950	COG2819	hydrolase of the alpha beta superfamily
LO005_RS11955	COG1960	acyl-CoA dehydrogenase activity
LO005_RS11960	COG1301	dicarboxylic acid transport
LO005_RS11965	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LO005_RS11970	COG3139	Protein of unknown function (DUF1315)
LO005_RS11975	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LO005_RS11980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LO005_RS11990	COG0494	nUDIX hydrolase
LO005_RS12000	COG0642	Histidine kinase
LO005_RS12015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LO005_RS12025	COG1720	tRNA m6t6A37 methyltransferase activity
LO005_RS12040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LO005_RS12045	COG0826	peptidase U32
LO005_RS12050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO005_RS12060	COG4598	ABC transporter
LO005_RS12065	COG4160	amino acid transport
LO005_RS12070	COG4215	(ABC) transporter
LO005_RS12085	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO005_RS12130	COG1131	(ABC) transporter
LO005_RS12135	COG0842	Transport permease protein
LO005_RS12150	COG0772	Belongs to the SEDS family
LO005_RS12155	COG2951	lytic endotransglycosylase activity
LO005_RS12180	COG2207	Transcriptional regulator
LO005_RS12195	COG0052	Belongs to the universal ribosomal protein uS2 family
LO005_RS12200	COG0024	Methionine aminopeptidase
LO005_RS12210	COG2223	nitrite transmembrane transporter activity
LO005_RS12220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LO005_RS12225	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LO005_RS12230	COG1960	acyl-CoA dehydrogenase activity
LO005_RS12245	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LO005_RS12250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
LO005_RS12255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LO005_RS12275	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LO005_RS12280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LO005_RS12285	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LO005_RS12320	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LO005_RS12330	COG0174	glutamine synthetase
LO005_RS12345	COG0582	viral genome integration into host DNA
LO005_RS12540	COG5410	chromosome segregation
LO005_RS12565	COG3293	Transposase
LO005_RS12690	COG4197	protein conserved in bacteria, prophage-related
LO005_RS12695	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LO005_RS12750	COG0527	aspartate kinase activity
LO005_RS12760	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LO005_RS12770	COG3038	cytochrome b561
LO005_RS12775	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LO005_RS12780	COG2252	PERMEase
LO005_RS12790	COG2072	flavoprotein involved in K transport
LO005_RS12805	COG1741	Belongs to the pirin family
LO005_RS12810	COG1309	transcriptional regulator
LO005_RS12820	COG0300	oxidoreductase activity
LO005_RS12825	COG2072	flavoprotein involved in K transport
LO005_RS12830	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
LO005_RS12875	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LO005_RS12890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LO005_RS12905	COG2814	Major facilitator Superfamily
LO005_RS12910	COG1024	Enoyl-CoA hydratase
LO005_RS12915	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS12925	COG1960	acyl-CoA dehydrogenase activity
LO005_RS12950	COG2186	Transcriptional regulator
LO005_RS12955	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS12965	COG4948	Mandelate Racemase Muconate Lactonizing
LO005_RS12970	COG2271	Major facilitator Superfamily
LO005_RS12975	COG2721	sulfolactate sulfo-lyase activity
LO005_RS12980	COG0697	spore germination
LO005_RS13015	COG1113	amino acid transport
LO005_RS13035	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS13055	COG0531	amino acid
LO005_RS13065	COG1113	amino acid transport
LO005_RS13100	COG3209	COG3209 Rhs family protein
LO005_RS13120	COG4269	membrane
LO005_RS13135	COG1902	pentaerythritol trinitrate reductase activity
LO005_RS13135	COG0446	pyridine nucleotide-disulphide oxidoreductase
LO005_RS13145	COG5001	Diguanylate cyclase
LO005_RS13145	COG3706	GGDEF domain
LO005_RS13145	COG2203	Gaf domain
LO005_RS13145	COG4251	negative regulation of phosphorylation
LO005_RS13155	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO005_RS13175	COG4172	Belongs to the ABC transporter superfamily
LO005_RS13180	COG4239	(ABC) transporter, permease
LO005_RS13185	COG4174	ABC transporter (Permease)
LO005_RS13195	COG1388	LysM domain
LO005_RS13195	COG0741	lytic transglycosylase activity
LO005_RS13195	COG0741	lytic transglycosylase activity
LO005_RS13195	COG1388	LysM domain
LO005_RS13200	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO005_RS13240	COG0583	DNA-binding transcription factor activity
LO005_RS13245	COG1279	arginine transmembrane transporter activity
LO005_RS13265	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO005_RS13270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LO005_RS13275	COG0006	proline dipeptidase activity
LO005_RS13315	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LO005_RS13335	COG3384	dioxygenase
LO005_RS13345	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
LO005_RS13350	COG2878	Part of a membrane complex involved in electron transport
LO005_RS13355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LO005_RS13380	COG0768	penicillin binding
LO005_RS13385	COG0742	ribosomal rna small subunit methyltransferase
LO005_RS13400	COG0830	nickel cation binding
LO005_RS13410	COG0804	urea catabolic process
LO005_RS13450	COG1253	flavin adenine dinucleotide binding
LO005_RS13455	COG2851	Citrate transporter
LO005_RS13505	COG1773	rubredoxin
LO005_RS13510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LO005_RS13520	COG0583	DNA-binding transcription factor activity
LO005_RS13550	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LO005_RS13555	COG4181	ATPase activity
LO005_RS13600	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LO005_RS13620	COG0306	phosphate transporter
LO005_RS13630	COG3958	Transketolase
LO005_RS13635	COG3959	Transketolase, thiamine diphosphate binding domain
LO005_RS13640	COG2271	Major facilitator Superfamily
LO005_RS13645	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS13650	COG0583	DNA-binding transcription factor activity
LO005_RS13665	COG2223	nitrite transmembrane transporter activity
LO005_RS13670	COG2207	Transcriptional regulator
LO005_RS13675	COG2066	Belongs to the glutaminase family
LO005_RS13680	COG0242	peptide deformylase activity
LO005_RS13685	COG0477	Major facilitator Superfamily
LO005_RS13695	COG0028	Belongs to the TPP enzyme family
LO005_RS13700	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS13710	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS13715	COG2267	carboxylic ester hydrolase activity
LO005_RS13725	COG2271	Major facilitator Superfamily
LO005_RS13740	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS13760	COG1414	Transcriptional regulator
LO005_RS13775	COG1024	Enoyl-CoA hydratase
LO005_RS13785	COG1215	transferase activity, transferring glycosyl groups
LO005_RS13790	COG0726	polysaccharide deacetylase
LO005_RS13790	COG1649	PFAM Uncharacterised BCR, COG1649
LO005_RS13800	COG4681	YaeQ
LO005_RS13810	COG0523	cobalamin synthesis protein
LO005_RS13820	COG1607	acyl-coa hydrolase
LO005_RS13830	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LO005_RS13835	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
LO005_RS13840	COG1309	transcriptional regulator
LO005_RS13865	COG2040	homocysteine
LO005_RS13870	COG0531	amino acid
LO005_RS13895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO005_RS13960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LO005_RS14000	COG0629	single-stranded DNA binding
LO005_RS14045	COG0582	viral genome integration into host DNA
LO005_RS14055	COG0405	Gamma-glutamyltransferase
LO005_RS14060	COG2814	Major facilitator Superfamily
LO005_RS14070	COG2050	protein possibly involved in aromatic compounds catabolism
LO005_RS14085	COG1090	epimerase
LO005_RS14105	COG0420	3'-5' exonuclease activity
LO005_RS14130	COG0735	belongs to the Fur family
LO005_RS14135	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LO005_RS14155	COG0121	glutamine amidotransferase
LO005_RS14170	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LO005_RS14180	COG0210	DNA helicase
LO005_RS14185	COG2885	chlorophyll binding
LO005_RS14190	COG0204	Acyl-transferase
LO005_RS14205	COG2894	cell division
LO005_RS14225	COG1280	lysine exporter protein (LysE YggA)
LO005_RS14230	COG1674	ftsk spoiiie
LO005_RS14235	COG0492	ferredoxin-NADP+ reductase activity
LO005_RS14240	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LO005_RS14250	COG0456	acetyltransferase
LO005_RS14295	COG1981	membrane
LO005_RS14310	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LO005_RS14310	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LO005_RS14330	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS14340	COG0657	acetylesterase activity
LO005_RS14350	COG0473	3-isopropylmalate dehydrogenase activity
LO005_RS14355	COG0583	DNA-binding transcription factor activity
LO005_RS14375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO005_RS14400	COG0564	pseudouridine synthase activity
LO005_RS14410	COG0358	DNA primase activity
LO005_RS14425	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LO005_RS14455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LO005_RS14485	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LO005_RS14495	COG0352	thiamine-phosphate diphosphorylase activity
LO005_RS14495	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LO005_RS14495	COG0351	phosphomethylpyrimidine kinase
LO005_RS14500	COG1652	LysM domain
LO005_RS14525	COG1399	metal-binding, possibly nucleic acid-binding protein
LO005_RS14530	COG3101	peptidyl-lysine hydroxylation
LO005_RS14535	COG0009	L-threonylcarbamoyladenylate synthase
LO005_RS14540	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
LO005_RS14545	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LO005_RS14560	COG4106	trans-aconitate 2-methyltransferase activity
LO005_RS14575	COG0596	Alpha beta hydrolase
LO005_RS14575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO005_RS14575	COG2226	methyltransferase
LO005_RS14580	COG1877	trehalose-phosphatase activity
LO005_RS14585	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
LO005_RS14590	COG2223	nitrite transmembrane transporter activity
LO005_RS14610	COG1196	nuclear chromosome segregation
LO005_RS14620	COG0730	response to heat
LO005_RS14635	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LO005_RS14645	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LO005_RS14695	COG0489	protein tyrosine kinase activity
LO005_RS14705	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO005_RS14705	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO005_RS14735	COG2515	1-aminocyclopropane-1-carboxylate deaminase
LO005_RS14740	COG2081	HI0933 family
LO005_RS14750	COG0668	transmembrane transport
LO005_RS14770	COG0583	DNA-binding transcription factor activity
LO005_RS14790	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LO005_RS14795	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LO005_RS14825	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LO005_RS14850	COG3706	GGDEF domain
LO005_RS14865	COG0745	RESPONSE REGULATOR receiver
LO005_RS14885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LO005_RS14925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LO005_RS14940	COG0583	DNA-binding transcription factor activity
LO005_RS14950	COG0583	DNA-binding transcription factor activity
LO005_RS14965	COG0583	DNA-binding transcription factor activity
LO005_RS14970	COG1053	succinate dehydrogenase
LO005_RS14985	COG1309	transcriptional regulator
LO005_RS14990	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LO005_RS14995	COG2814	Major facilitator Superfamily
LO005_RS15000	COG1960	acyl-CoA dehydrogenase activity
LO005_RS15005	COG0583	DNA-binding transcription factor activity
LO005_RS15010	COG1063	alcohol dehydrogenase
LO005_RS15040	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LO005_RS15045	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LO005_RS15050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LO005_RS15070	COG2132	Multicopper oxidase
LO005_RS15080	COG0561	phosphatase activity
LO005_RS15085	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LO005_RS15110	COG1214	PFAM Peptidase M22, glycoprotease
LO005_RS15150	COG3293	Transposase
LO005_RS15165	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LO005_RS15175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LO005_RS15180	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LO005_RS15185	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LO005_RS15245	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LO005_RS15255	COG1846	Transcriptional regulator
LO005_RS15260	COG1764	response to oxidative stress
LO005_RS15285	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LO005_RS15285	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LO005_RS15300	COG0037	tRNA processing
LO005_RS15310	COG0248	Ppx GppA phosphatase
LO005_RS15340	COG0072	phenylalanine-tRNA ligase activity
LO005_RS15385	COG1238	metal cluster binding
LO005_RS15390	COG0625	glutathione transferase activity
LO005_RS15405	COG0318	PFAM AMP-dependent synthetase and ligase
LO005_RS15410	COG3028	Belongs to the UPF0307 family
LO005_RS15415	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LO005_RS15435	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
LO005_RS15440	COG0617	tRNA 3'-terminal CCA addition
LO005_RS15445	COG1555	photosystem II stabilization
LO005_RS15450	COG3956	TIGRFAM MazG family protein
LO005_RS15460	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LO005_RS15480	COG2205	protein histidine kinase activity
LO005_RS15480	COG5002	protein histidine kinase activity
LO005_RS15480	COG0784	Response regulator, receiver
LO005_RS15485	COG1024	Enoyl-CoA hydratase
LO005_RS15490	COG2084	Dehydrogenase
LO005_RS15495	COG3622	Belongs to the hyi family
LO005_RS15525	COG0697	spore germination
LO005_RS15535	COG2814	Major facilitator Superfamily
LO005_RS15545	COG2072	flavoprotein involved in K transport
LO005_RS15550	COG0492	ferredoxin-NADP+ reductase activity
LO005_RS15555	COG0431	NADPH-dependent FMN reductase
LO005_RS15560	COG0798	PFAM Bile acid sodium symporter
LO005_RS15570	COG0640	Transcriptional regulator
LO005_RS15615	COG2132	Multicopper oxidase
LO005_RS15630	COG2205	protein histidine kinase activity
LO005_RS15715	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LO005_RS15725	COG0583	DNA-binding transcription factor activity
LO005_RS15735	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LO005_RS15745	COG0084	hydrolase, TatD family'
LO005_RS15760	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LO005_RS15790	COG0440	acetolactate synthase activity
LO005_RS15795	COG0028	Belongs to the TPP enzyme family
LO005_RS15820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LO005_RS15825	COG1136	(ABC) transporter
LO005_RS15825	COG0577	efflux transmembrane transporter activity
LO005_RS15830	COG1538	Outer membrane efflux protein
LO005_RS15845	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LO005_RS15850	COG1162	GTPase activity
LO005_RS15860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LO005_RS15900	COG1426	Protein conserved in bacteria
LO005_RS15935	COG0793	Belongs to the peptidase S41A family
LO005_RS15960	COG1012	belongs to the aldehyde dehydrogenase family
LO005_RS15965	COG3265	gluconokinase activity
LO005_RS15975	COG0800	Aldolase
LO005_RS15985	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LO005_RS15990	COG0857	belongs to the CobB CobQ family
LO005_RS15990	COG0280	phosphate acetyltransferase
LO005_RS15995	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
LO005_RS15995	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
LO005_RS16015	COG0740	serine-type endopeptidase activity
LO005_RS16025	COG4774	siderophore transport
LO005_RS16035	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LO005_RS16045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LO005_RS16045	COG2813	Specifically methylates the guanine in position
LO005_RS16145	COG0788	formyltetrahydrofolate deformylase activity
LO005_RS16170	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LO005_RS16170	COG4651	solute:proton antiporter activity
LO005_RS16190	COG0724	RNA recognition motif
LO005_RS16195	COG0210	DNA helicase
LO005_RS16220	COG1733	regulation of RNA biosynthetic process
LO005_RS16230	COG2900	Belongs to the SlyX family
LO005_RS16235	COG0488	(ABC) transporter
LO005_RS16240	COG1280	lysine exporter protein (LysE YggA)
LO005_RS16245	COG1560	Kdo2-lipid A biosynthetic process
LO005_RS16255	COG1301	dicarboxylic acid transport
LO005_RS16280	COG0252	asparaginase activity
LO005_RS16310	COG0473	3-isopropylmalate dehydrogenase activity
LO005_RS16365	COG0583	DNA-binding transcription factor activity
LO005_RS16375	COG0625	glutathione transferase activity
LO005_RS16380	COG2378	regulation of single-species biofilm formation
LO005_RS16385	COG0546	phosphoglycolate phosphatase activity
LO005_RS16395	COG1530	ribonuclease E activity
LO005_RS16400	COG0318	PFAM AMP-dependent synthetase and ligase
LO005_RS16415	COG0583	DNA-binding transcription factor activity
LO005_RS16420	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS16425	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LO005_RS16435	COG0534	Mate efflux family protein
LO005_RS16450	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LO005_RS16480	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LO005_RS16480	COG0493	'glutamate synthase
LO005_RS16490	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LO005_RS16495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LO005_RS16510	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LO005_RS16520	COG0644	oxidoreductase
LO005_RS16520	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
LO005_RS16530	COG0425	Belongs to the sulfur carrier protein TusA family
LO005_RS16535	COG4535	Mg2 and Co2 transporter CorC
LO005_RS16545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LO005_RS16565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LO005_RS16570	COG0475	glutathione-regulated potassium exporter activity
LO005_RS16570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LO005_RS16585	COG0484	heat shock protein binding
LO005_RS16590	COG0789	Transcriptional regulator
LO005_RS16595	COG0598	Magnesium transport protein CorA
LO005_RS16610	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LO005_RS16615	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LO005_RS16620	COG1074	ATP-dependent DNA helicase activity
LO005_RS16625	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LO005_RS16645	COG2226	methyltransferase
LO005_RS16655	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LO005_RS16670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LO005_RS16685	COG2111	Na H antiporter
LO005_RS16685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LO005_RS16690	COG1006	Multisubunit Na H antiporter MnhC subunit
LO005_RS16695	COG0651	ATP synthesis coupled electron transport
LO005_RS16700	COG1863	multisubunit Na H antiporter MnhE subunit
LO005_RS16705	COG2212	antiporter activity
LO005_RS16710	COG1320	monovalent cation:proton antiporter activity
LO005_RS16725	COG0195	Participates in both transcription termination and antitermination
LO005_RS16775	COG0237	dephospho-CoA kinase activity
LO005_RS16785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LO005_RS16800	COG0497	DNA recombination
LO005_RS16810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LO005_RS16840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LO005_RS16840	COG2169	Transcriptional regulator
LO005_RS16845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LO005_RS16900	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
LO005_RS16915	COG0326	Molecular chaperone. Has ATPase activity
LO005_RS16930	COG2056	Na+-H+ antiporter family
LO005_RS17030	COG0546	phosphoglycolate phosphatase activity
LO005_RS17035	COG1716	ATPase activity
LO005_RS17080	COG0181	hydroxymethylbilane synthase activity
LO005_RS17090	COG3275	phosphorelay sensor kinase activity
LO005_RS17115	COG0697	spore germination
LO005_RS17140	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
LO005_RS17145	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LO005_RS17150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LO005_RS17155	COG0772	Belongs to the SEDS family
LO005_RS17180	COG4974	Belongs to the 'phage' integrase family
LO005_RS17185	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO005_RS17195	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LO005_RS17205	COG2197	response regulator
LO005_RS17220	COG0793	Belongs to the peptidase S41A family
LO005_RS17225	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LO005_RS17230	COG0795	lipopolysaccharide-transporting ATPase activity
LO005_RS17270	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LO005_RS17270	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LO005_RS17280	COG0004	ammonium transporteR
LO005_RS17285	COG0347	Belongs to the P(II) protein family
LO005_RS17295	COG0606	chelatase, subunit chli
LO005_RS17310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LO005_RS17330	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LO005_RS17345	COG0318	PFAM AMP-dependent synthetase and ligase
LO005_RS17355	COG0477	Major facilitator Superfamily
LO005_RS17360	COG2860	membrane
LO005_RS17370	COG1253	flavin adenine dinucleotide binding
LO005_RS17380	COG0477	Major facilitator Superfamily
LO005_RS17390	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LO005_RS17430	COG0655	NAD(P)H dehydrogenase (quinone) activity
LO005_RS17440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LO005_RS17510	COG0758	DNA mediated transformation
LO005_RS17520	COG0697	spore germination
LO005_RS17525	COG1309	transcriptional regulator
LO005_RS17540	COG0386	Belongs to the glutathione peroxidase family
LO005_RS17605	COG1121	(ABC) transporter
LO005_RS17610	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LO005_RS17615	COG1280	lysine exporter protein (LysE YggA)
LO005_RS17620	COG2837	iron assimilation
LO005_RS17625	COG0281	malic enzyme
LO005_RS17670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LO005_RS17670	COG0519	Catalyzes the synthesis of GMP from XMP
LO005_RS17675	COG4399	Belongs to the UPF0754 family
LO005_RS17680	COG2259	Doxx family
LO005_RS17685	COG0586	Pfam SNARE associated Golgi protein
LO005_RS17700	COG1192	Involved in chromosome partitioning
LO005_RS17710	COG0271	Belongs to the BolA IbaG family
LO005_RS17750	COG3321	synthase
LO005_RS17750	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
LO005_RS17750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LO005_RS17750	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LO005_RS17755	COG1960	acyl-CoA dehydrogenase activity
LO005_RS17765	COG2197	response regulator
LO005_RS17775	COG3916	Acyl-homoserine-lactone synthase
LO005_RS17780	COG0477	Major facilitator Superfamily
LO005_RS17785	COG1024	Enoyl-CoA hydratase
LO005_RS17790	COG1024	Enoyl-CoA hydratase
LO005_RS17795	COG1960	acyl-CoA dehydrogenase activity
LO005_RS17800	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LO005_RS17820	COG1113	amino acid transport
LO005_RS17825	COG1113	amino acid transport
LO005_RS17830	COG0251	oxidation-reduction process
LO005_RS17870	COG0564	pseudouridine synthase activity
LO005_RS17915	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LO005_RS17930	COG1802	Transcriptional regulator
LO005_RS17940	COG1448	Aminotransferase
LO005_RS17945	COG0277	FAD linked oxidase domain protein
LO005_RS17955	COG2186	Transcriptional regulator
LO005_RS17965	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LO005_RS17975	COG3293	Transposase
LO005_RS17990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LO005_RS18005	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LO005_RS18010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LO005_RS18015	COG1216	Glycosyl transferase, family 2
LO005_RS18045	COG2089	acid synthase
LO005_RS18060	COG1083	cytidylyl-transferase
LO005_RS18065	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LO005_RS18070	COG1086	Polysaccharide biosynthesis protein
LO005_RS18075	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
LO005_RS18080	COG1596	polysaccharide export
LO005_RS18105	COG0728	peptidoglycan biosynthetic process
LO005_RS18110	COG3023	N-Acetylmuramoyl-L-alanine amidase
LO005_RS18170	COG0546	phosphoglycolate phosphatase activity
LO005_RS18175	COG1028	Short-chain dehydrogenase reductase Sdr
LO005_RS18195	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO005_RS18200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LO005_RS18205	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LO005_RS18210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LO005_RS18215	COG1116	anion transmembrane transporter activity
LO005_RS18220	COG1309	transcriptional regulator
LO005_RS18225	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LO005_RS18235	COG0196	riboflavin kinase activity
LO005_RS18240	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LO005_RS18250	COG1047	Peptidyl-prolyl cis-trans
LO005_RS18290	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LO005_RS18295	COG0657	acetylesterase activity
LO005_RS18315	COG0583	DNA-binding transcription factor activity
LO005_RS18345	COG2951	lytic endotransglycosylase activity
LO005_RS18350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LO005_RS18365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LO005_RS18375	COG0671	phosphoesterase, PA-phosphatase related
LO005_RS18380	COG0861	Integral membrane protein TerC family
LO005_RS18390	COG0754	glutathionylspermidine amidase activity
LO005_RS18400	COG0402	S-adenosylhomocysteine deaminase activity
LO005_RS18415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO005_RS18420	COG1230	cation diffusion facilitator family transporter
LO005_RS18435	COG0706	membrane insertase activity
LO005_RS18570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LO005_RS18590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LO005_RS18675	COG3586	endonuclease activity
LO005_RS18725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LO005_RS18735	COG2015	COG2015, Alkyl sulfatase and related hydrolases
LO005_RS18785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LO005_RS18790	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LO005_RS18790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LO005_RS18840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LO005_RS18840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LO005_RS18855	COG0587	DNA-directed DNA polymerase activity
LO005_RS18875	COG0587	DNA-directed DNA polymerase activity
LO005_RS18910	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
LO005_RS18970	COG0358	DNA primase activity
LO005_RS19020	COG2826	transposase and inactivated derivatives, IS30 family
LO005_RS19030	COG2826	transposase and inactivated derivatives, IS30 family
LO005_RS19060	COG0741	lytic transglycosylase activity
LO005_RS19095	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LO005_RS19175	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LO005_RS19245	COG1525	nuclease
LO005_RS19305	COG1475	DNA binding
LO005_RS19320	COG3853	Toxic anion resistance protein (TelA)
LO005_RS19485	COG0484	heat shock protein binding