locus-tag	class	description
FE003_RS00010	COG0592	DNA-directed DNA polymerase activity
FE003_RS00020	COG0187	DNA topoisomerase II activity
FE003_RS00030	COG0586	Pfam SNARE associated Golgi protein
FE003_RS00035	COG0488	(ABC) transporter
FE003_RS00060	COG0596	Alpha beta hydrolase
FE003_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FE003_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FE003_RS00115	COG0733	neurotransmitter:sodium symporter activity
FE003_RS00155	COG2233	PERMEase
FE003_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE003_RS00205	COG2814	Major facilitator Superfamily
FE003_RS00210	COG0656	L-ascorbic acid biosynthetic process
FE003_RS00215	COG0583	DNA-binding transcription factor activity
FE003_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE003_RS00235	COG1064	alcohol dehydrogenase
FE003_RS00240	COG2818	Glycosylase
FE003_RS00255	COG1194	a g-specific adenine glycosylase
FE003_RS00275	COG2983	Belongs to the UPF0260 family
FE003_RS00280	COG2133	pyrroloquinoline quinone binding
FE003_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FE003_RS00290	COG2116	formate transmembrane transporter activity
FE003_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE003_RS00315	COG1335	isochorismatase
FE003_RS00320	COG0385	Bile acid
FE003_RS00325	COG0534	Mate efflux family protein
FE003_RS00330	COG1683	Conserved Protein
FE003_RS00350	COG0625	glutathione transferase activity
FE003_RS00360	COG1113	amino acid transport
FE003_RS00370	COG0523	cobalamin synthesis protein
FE003_RS00380	COG2188	Transcriptional regulator
FE003_RS00410	COG0010	Belongs to the arginase family
FE003_RS00425	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FE003_RS00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FE003_RS00440	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FE003_RS00445	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FE003_RS00550	COG0534	Mate efflux family protein
FE003_RS00555	COG0436	Aminotransferase
FE003_RS00560	COG2733	membrane
FE003_RS00575	COG2918	glutathione biosynthetic process
FE003_RS00590	COG0791	NLP P60 protein
FE003_RS00590	COG1388	LysM domain
FE003_RS00605	COG3150	esterase
FE003_RS00615	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS00620	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FE003_RS00630	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE003_RS00640	COG2233	PERMEase
FE003_RS00645	COG2351	hydroxyisourate hydrolase activity
FE003_RS00680	COG3706	GGDEF domain
FE003_RS00695	COG1393	Belongs to the ArsC family
FE003_RS00700	COG0708	Exodeoxyribonuclease III
FE003_RS00720	COG0189	ligase activity
FE003_RS00740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FE003_RS00750	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FE003_RS00765	COG4942	peptidase
FE003_RS00775	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE003_RS00785	COG2119	membrane
FE003_RS00790	COG4774	siderophore transport
FE003_RS00795	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE003_RS00795	COG0426	domain, Protein
FE003_RS00820	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FE003_RS00840	COG1902	pentaerythritol trinitrate reductase activity
FE003_RS00845	COG1519	Transferase
FE003_RS00850	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FE003_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE003_RS00880	COG1335	isochorismatase
FE003_RS00885	COG1522	sequence-specific DNA binding
FE003_RS00890	COG3328	transposase activity
FE003_RS00915	COG2205	protein histidine kinase activity
FE003_RS00915	COG0784	Response regulator, receiver
FE003_RS00915	COG2198	Histidine kinase
FE003_RS00920	COG3162	membrane
FE003_RS00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE003_RS00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FE003_RS00965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FE003_RS00970	COG1309	transcriptional regulator
FE003_RS00990	COG0352	thiamine-phosphate diphosphorylase activity
FE003_RS00990	COG0351	phosphomethylpyrimidine kinase
FE003_RS00990	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FE003_RS01000	COG2814	Major facilitator Superfamily
FE003_RS01015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FE003_RS01025	COG1113	amino acid transport
FE003_RS01035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FE003_RS01040	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS01050	COG1335	isochorismatase
FE003_RS01080	COG2814	Major facilitator Superfamily
FE003_RS01085	COG0583	DNA-binding transcription factor activity
FE003_RS01105	COG0667	Aldo Keto reductase
FE003_RS01140	COG1733	regulation of RNA biosynthetic process
FE003_RS01150	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE003_RS01215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FE003_RS01230	COG2329	Antibiotic biosynthesis monooxygenase
FE003_RS01260	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FE003_RS01290	COG0427	acetyl-CoA hydrolase
FE003_RS01315	COG0659	secondary active sulfate transmembrane transporter activity
FE003_RS01320	COG4221	oxidoreductase activity
FE003_RS01325	COG2873	o-acetylhomoserine
FE003_RS01330	COG0488	(ABC) transporter
FE003_RS01415	COG0833	amino acid
FE003_RS01460	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FE003_RS01465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FE003_RS01480	COG2226	methyltransferase
FE003_RS01530	COG0070	glutamate synthase
FE003_RS01530	COG0069	glutamate synthase activity
FE003_RS01530	COG0067	glutamate synthase
FE003_RS01535	COG0493	'glutamate synthase
FE003_RS01545	COG1704	LemA family
FE003_RS01550	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FE003_RS01570	COG3307	-O-antigen
FE003_RS01590	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE003_RS01605	COG0194	GDP metabolic process
FE003_RS01655	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FE003_RS01675	COG5380	lipid catabolic process
FE003_RS01680	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FE003_RS01705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FE003_RS01710	COG0277	FAD linked oxidase domain protein
FE003_RS01720	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FE003_RS01725	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE003_RS01740	COG1289	transmembrane transporter activity
FE003_RS01750	COG0628	permease
FE003_RS01755	COG1192	Involved in chromosome partitioning
FE003_RS01785	COG0833	amino acid
FE003_RS01790	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FE003_RS01795	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE003_RS01805	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS01845	COG0583	DNA-binding transcription factor activity
FE003_RS01890	COG0517	IMP dehydrogenase activity
FE003_RS01895	COG1983	PspC domain protein
FE003_RS01905	COG1960	acyl-CoA dehydrogenase activity
FE003_RS01920	COG0408	coproporphyrinogen oxidase activity
FE003_RS01940	COG0513	Belongs to the DEAD box helicase family
FE003_RS01950	COG1127	ABC transporter
FE003_RS01955	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FE003_RS01965	COG2854	intermembrane phospholipid transfer
FE003_RS01975	COG0598	Magnesium transport protein CorA
FE003_RS01985	COG0494	nUDIX hydrolase
FE003_RS01990	COG1040	competence protein
FE003_RS01995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FE003_RS02015	COG1946	Acyl-CoA thioesterase
FE003_RS02020	COG1301	dicarboxylic acid transport
FE003_RS02035	COG1959	2 iron, 2 sulfur cluster binding
FE003_RS02040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE003_RS02040	COG1017	nitric oxide dioxygenase activity
FE003_RS02045	COG0433	COG0433 Predicted ATPase
FE003_RS02050	COG0626	cystathionine gamma-synthase activity
FE003_RS02205	COG1960	acyl-CoA dehydrogenase activity
FE003_RS02210	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FE003_RS02240	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FE003_RS02245	COG0339	signal peptide processing
FE003_RS02250	COG0557	exoribonuclease II activity
FE003_RS02295	COG0179	Fumarylacetoacetate (FAA) hydrolase
FE003_RS02300	COG2169	Transcriptional regulator
FE003_RS02305	COG0697	spore germination
FE003_RS02310	COG1295	ribonuclease BN
FE003_RS02345	COG1702	phosphate starvation-inducible protein PhoH
FE003_RS02355	COG0741	lytic transglycosylase activity
FE003_RS02355	COG0739	heme binding
FE003_RS02355	COG1196	nuclear chromosome segregation
FE003_RS02385	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FE003_RS02390	COG1183	phosphatidylcholine synthase activity
FE003_RS02435	COG1960	acyl-CoA dehydrogenase activity
FE003_RS02440	COG1309	transcriptional regulator
FE003_RS02455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE003_RS02460	COG1960	acyl-CoA dehydrogenase activity
FE003_RS02480	COG2969	positive regulation of protein catabolic process
FE003_RS02490	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FE003_RS02505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FE003_RS02510	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FE003_RS02530	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FE003_RS02540	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE003_RS02545	COG1408	metallophosphoesterase
FE003_RS02555	COG2199	diguanylate cyclase activity
FE003_RS02615	COG1607	acyl-coa hydrolase
FE003_RS02645	COG2350	Protein conserved in bacteria
FE003_RS02655	COG0613	PHP domain protein
FE003_RS02660	COG3781	membrane
FE003_RS02670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FE003_RS02675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FE003_RS02685	COG1862	Preprotein translocase
FE003_RS02725	COG2826	transposase and inactivated derivatives, IS30 family
FE003_RS02740	COG2205	protein histidine kinase activity
FE003_RS02745	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FE003_RS02765	COG0726	polysaccharide deacetylase
FE003_RS02770	COG0463	Glycosyl transferase, family 2
FE003_RS02775	COG0438	transferase activity, transferring glycosyl groups
FE003_RS02845	COG0625	glutathione transferase activity
FE003_RS02850	COG0583	DNA-binding transcription factor activity
FE003_RS02855	COG1960	acyl-CoA dehydrogenase activity
FE003_RS02860	COG1960	acyl-CoA dehydrogenase activity
FE003_RS02870	COG2205	protein histidine kinase activity
FE003_RS02875	COG0745	RESPONSE REGULATOR receiver
FE003_RS02880	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FE003_RS02900	COG2096	Adenosyltransferase
FE003_RS02950	COG0285	dihydrofolate synthase activity
FE003_RS02970	COG0450	alkyl hydroperoxide reductase
FE003_RS02985	COG0477	Major facilitator Superfamily
FE003_RS02990	COG1272	protein, Hemolysin III
FE003_RS03020	COG0183	Belongs to the thiolase family
FE003_RS03025	COG2207	Transcriptional regulator
FE003_RS03045	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE003_RS03065	COG0183	Belongs to the thiolase family
FE003_RS03075	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FE003_RS03075	COG2885	chlorophyll binding
FE003_RS03085	COG1690	Belongs to the RtcB family
FE003_RS03090	COG0833	amino acid
FE003_RS03100	COG2233	PERMEase
FE003_RS03105	COG1217	gtp-binding protein TYPA
FE003_RS03130	COG2094	Belongs to the DNA glycosylase MPG family
FE003_RS03135	COG4772	TonB-dependent receptor
FE003_RS03140	COG1902	pentaerythritol trinitrate reductase activity
FE003_RS03145	COG0679	Auxin Efflux Carrier
FE003_RS03155	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE003_RS03160	COG0354	folic acid binding
FE003_RS03170	COG3189	MarR family transcriptional regulator
FE003_RS03175	COG2824	Alkylphosphonate utilization operon protein PhnA
FE003_RS03180	COG3422	double-strand break repair
FE003_RS03220	COG0840	transmembrane signaling receptor activity
FE003_RS03240	COG5510	response to toxic substance
FE003_RS03250	COG2832	Protein of unknown function (DUF454)
FE003_RS03255	COG1376	ErfK ybiS ycfS ynhG family protein
FE003_RS03295	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FE003_RS03305	COG1289	transmembrane transporter activity
FE003_RS03310	COG2814	Major facilitator Superfamily
FE003_RS03330	COG1115	amino acid carrier protein
FE003_RS03335	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE003_RS03340	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FE003_RS03345	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FE003_RS03375	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FE003_RS03385	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FE003_RS03390	COG1077	Cell shape determining protein MreB Mrl
FE003_RS03395	COG1792	Involved in formation and maintenance of cell shape
FE003_RS03400	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FE003_RS03405	COG0424	maF-like protein
FE003_RS03410	COG1530	ribonuclease E activity
FE003_RS03420	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE003_RS03430	COG0560	Phosphoserine phosphatase
FE003_RS03440	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE003_RS03465	COG2207	Transcriptional regulator
FE003_RS03485	COG1113	amino acid transport
FE003_RS03490	COG2828	Protein conserved in bacteria
FE003_RS03495	COG0142	geranyltranstransferase activity
FE003_RS03500	COG2315	Protein conserved in bacteria
FE003_RS03515	COG1752	Esterase of the alpha-beta hydrolase superfamily
FE003_RS03535	COG2194	sulfuric ester hydrolase activity
FE003_RS03540	COG0745	RESPONSE REGULATOR receiver
FE003_RS03545	COG0642	Histidine kinase
FE003_RS03555	COG0004	ammonium transporteR
FE003_RS03565	COG0583	DNA-binding transcription factor activity
FE003_RS03585	COG0525	valine-tRNA ligase activity
FE003_RS03595	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS03605	COG0393	Putative heavy-metal-binding
FE003_RS03610	COG0393	Putative heavy-metal-binding
FE003_RS03615	COG1538	Outer membrane efflux protein
FE003_RS03625	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE003_RS03630	COG0671	phosphoesterase, PA-phosphatase related
FE003_RS03660	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FE003_RS03675	COG1648	precorrin-2 dehydrogenase activity
FE003_RS03675	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FE003_RS03680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FE003_RS03685	COG1733	regulation of RNA biosynthetic process
FE003_RS03695	COG0531	amino acid
FE003_RS03710	COG0321	lipoyl(octanoyl) transferase activity
FE003_RS03715	COG2921	Belongs to the UPF0250 family
FE003_RS03755	COG2009	succinate dehydrogenase
FE003_RS03760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FE003_RS03765	COG1053	succinate dehydrogenase
FE003_RS03770	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FE003_RS03795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE003_RS03815	COG2354	Protein conserved in bacteria
FE003_RS03820	COG2321	neutral zinc metallopeptidase
FE003_RS03870	COG2843	Capsule synthesis protein
FE003_RS03885	COG0589	response to stress
FE003_RS03905	COG0505	Belongs to the CarA family
FE003_RS03930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE003_RS03935	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FE003_RS03985	COG0477	Major facilitator Superfamily
FE003_RS03990	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FE003_RS04005	COG1597	lipid kinase activity
FE003_RS04010	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FE003_RS04020	COG2826	transposase and inactivated derivatives, IS30 family
FE003_RS04045	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE003_RS04050	COG0584	glycerophosphoryl diester phosphodiesterase
FE003_RS04070	COG0741	lytic transglycosylase activity
FE003_RS04095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FE003_RS04110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE003_RS04140	COG0778	Nitroreductase
FE003_RS04155	COG1929	Belongs to the glycerate kinase type-1 family
FE003_RS04160	COG0243	molybdopterin cofactor binding
FE003_RS04165	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FE003_RS04170	COG3339	Conserved Protein
FE003_RS04180	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FE003_RS04195	COG1113	amino acid transport
FE003_RS04205	COG0019	diaminopimelate decarboxylase activity
FE003_RS04215	COG1280	lysine exporter protein (LysE YggA)
FE003_RS04220	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FE003_RS04250	COG0463	Glycosyl transferase, family 2
FE003_RS04270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE003_RS04300	COG4591	ABC-type transport system involved in lipoprotein release permease component
FE003_RS04305	COG1136	(ABC) transporter
FE003_RS04310	COG0658	competence protein
FE003_RS04310	COG2333	competence protein COMEC
FE003_RS04320	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FE003_RS04320	COG0616	signal peptide processing
FE003_RS04325	COG0596	Alpha beta hydrolase
FE003_RS04330	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FE003_RS04340	COG0628	permease
FE003_RS04375	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE003_RS04395	COG0823	Involved in the tonB-independent uptake of proteins
FE003_RS04415	COG0824	Thioesterase
FE003_RS04420	COG1473	amidohydrolase
FE003_RS04440	COG0047	phosphoribosylformylglycinamidine synthase activity
FE003_RS04440	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FE003_RS04445	COG2814	Major facilitator Superfamily
FE003_RS04455	COG1024	Enoyl-CoA hydratase
FE003_RS04460	COG1051	belongs to the nudix hydrolase family
FE003_RS04460	COG1056	cytidyltransferase-related domain
FE003_RS04470	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FE003_RS04485	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FE003_RS04500	COG4625	pathogenesis
FE003_RS04505	COG0583	DNA-binding transcription factor activity
FE003_RS04510	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FE003_RS04515	COG4208	sulfate ABC transporter
FE003_RS04520	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FE003_RS04530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FE003_RS04535	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FE003_RS04540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FE003_RS04560	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE003_RS04575	COG0681	Belongs to the peptidase S26 family
FE003_RS04590	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FE003_RS04600	COG1381	Involved in DNA repair and RecF pathway recombination
FE003_RS04605	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FE003_RS04615	COG4221	oxidoreductase activity
FE003_RS04645	COG0436	Aminotransferase
FE003_RS04665	COG0556	nucleotide-excision repair
FE003_RS04720	COG2070	2-Nitropropane dioxygenase
FE003_RS04750	COG1215	transferase activity, transferring glycosyl groups
FE003_RS04765	COG0415	Belongs to the DNA photolyase family
FE003_RS04775	COG1252	NADH dehydrogenase
FE003_RS04780	COG1686	Belongs to the peptidase S11 family
FE003_RS04795	COG1187	pseudouridine synthase activity
FE003_RS04820	COG0477	Major facilitator Superfamily
FE003_RS04825	COG0583	DNA-binding transcription factor activity
FE003_RS04830	COG1823	symporter activity
FE003_RS04840	COG0612	Peptidase, M16
FE003_RS04865	COG0352	thiamine-phosphate diphosphorylase activity
FE003_RS04900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE003_RS04915	COG1309	transcriptional regulator
FE003_RS04925	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FE003_RS04930	COG0076	glutamate decarboxylase activity
FE003_RS04940	COG1522	sequence-specific DNA binding
FE003_RS04945	COG3961	Belongs to the TPP enzyme family
FE003_RS04950	COG1113	amino acid transport
FE003_RS04955	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FE003_RS04960	COG0573	inorganic phosphate transmembrane transporter activity
FE003_RS04970	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FE003_RS04975	COG0616	signal peptide processing
FE003_RS05010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FE003_RS05015	COG1686	Belongs to the peptidase S11 family
FE003_RS05040	COG0583	DNA-binding transcription factor activity
FE003_RS05045	COG1067	ATP-dependent peptidase activity
FE003_RS05090	COG1966	Carbon starvation protein
FE003_RS05095	COG2879	small protein
FE003_RS05130	COG2508	Transcriptional regulator
FE003_RS05130	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FE003_RS05150	COG1113	amino acid transport
FE003_RS05155	COG0583	DNA-binding transcription factor activity
FE003_RS05160	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FE003_RS05165	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FE003_RS05175	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS05180	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE003_RS05185	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FE003_RS05185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE003_RS05220	COG2814	Major facilitator Superfamily
FE003_RS05225	COG4948	Mandelate Racemase Muconate Lactonizing
FE003_RS05235	COG1309	transcriptional regulator
FE003_RS05255	COG1741	Belongs to the pirin family
FE003_RS05265	COG2964	Protein conserved in bacteria
FE003_RS05280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE003_RS05285	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE003_RS05290	COG4605	iron ion homeostasis
FE003_RS05295	COG4604	ABC transporter, ATP-binding protein
FE003_RS05300	COG4607	ABC-type enterochelin transport system periplasmic component
FE003_RS05305	COG4774	siderophore transport
FE003_RS05315	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FE003_RS05320	COG1021	2,3-dihydroxybenzoate-AMP ligase
FE003_RS05325	COG1535	isochorismatase
FE003_RS05325	COG3433	isochorismatase activity
FE003_RS05340	COG1132	(ABC) transporter
FE003_RS05345	COG1132	(ABC) transporter
FE003_RS05350	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FE003_RS05360	COG1169	isochorismate synthase
FE003_RS05375	COG3739	integral membrane protein
FE003_RS05400	COG0302	gtp cyclohydrolase
FE003_RS05410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FE003_RS05440	COG0308	aminopeptidase N
FE003_RS05445	COG0512	Glutamine amidotransferase of anthranilate synthase
FE003_RS05620	COG5410	chromosome segregation
FE003_RS05830	COG0582	viral genome integration into host DNA
FE003_RS05845	COG0174	glutamine synthetase
FE003_RS05855	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FE003_RS05890	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FE003_RS05895	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FE003_RS05900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FE003_RS05920	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FE003_RS05925	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FE003_RS05930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FE003_RS05945	COG1960	acyl-CoA dehydrogenase activity
FE003_RS05950	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FE003_RS05955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE003_RS05965	COG2223	nitrite transmembrane transporter activity
FE003_RS05975	COG0024	Methionine aminopeptidase
FE003_RS05980	COG0052	Belongs to the universal ribosomal protein uS2 family
FE003_RS06030	COG2951	lytic endotransglycosylase activity
FE003_RS06035	COG0772	Belongs to the SEDS family
FE003_RS06050	COG0842	Transport permease protein
FE003_RS06055	COG1131	(ABC) transporter
FE003_RS06100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE003_RS06115	COG4215	(ABC) transporter
FE003_RS06120	COG4160	amino acid transport
FE003_RS06125	COG4598	ABC transporter
FE003_RS06135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE003_RS06140	COG0826	peptidase U32
FE003_RS06145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE003_RS06160	COG1720	tRNA m6t6A37 methyltransferase activity
FE003_RS06170	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FE003_RS06185	COG0642	Histidine kinase
FE003_RS06195	COG0494	nUDIX hydrolase
FE003_RS06205	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FE003_RS06210	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FE003_RS06215	COG3139	Protein of unknown function (DUF1315)
FE003_RS06220	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FE003_RS06230	COG1301	dicarboxylic acid transport
FE003_RS06235	COG1960	acyl-CoA dehydrogenase activity
FE003_RS06240	COG2819	hydrolase of the alpha beta superfamily
FE003_RS06250	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FE003_RS06260	COG2195	Cleaves the N-terminal amino acid of tripeptides
FE003_RS06265	COG1234	tRNA 3'-trailer cleavage
FE003_RS06295	COG2363	Small membrane protein
FE003_RS06315	COG0513	Belongs to the DEAD box helicase family
FE003_RS06325	COG0778	Nitroreductase
FE003_RS06355	COG1286	toxin biosynthetic process
FE003_RS06380	COG4783	chaperone-mediated protein folding
FE003_RS06385	COG1610	YqeY-like protein
FE003_RS06485	COG3111	PFAM Bacterial OB fold (BOF) protein
FE003_RS06515	COG3243	poly(R)-hydroxyalkanoic acid synthase
FE003_RS06520	COG0786	glutamate:sodium symporter activity
FE003_RS06530	COG2186	Transcriptional regulator
FE003_RS06580	COG0477	Major facilitator Superfamily
FE003_RS06620	COG2985	domain, Protein
FE003_RS06630	COG2995	paraquat-inducible protein a
FE003_RS06635	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FE003_RS06635	COG3008	intermembrane lipid transfer
FE003_RS06645	COG1794	racemase activity, acting on amino acids and derivatives
FE003_RS06675	COG1301	dicarboxylic acid transport
FE003_RS06685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE003_RS06690	COG2011	ABC-type metal ion transport system permease component
FE003_RS06695	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FE003_RS06700	COG1464	Belongs to the NlpA lipoprotein family
FE003_RS06705	COG0151	Belongs to the GarS family
FE003_RS06710	COG0138	bifunctional purine biosynthesis protein purh
FE003_RS06715	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FE003_RS06745	COG2308	Evidence 4 Homologs of previously reported genes of
FE003_RS06755	COG1305	Transglutaminase-like
FE003_RS06765	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FE003_RS06770	COG0305	Participates in initiation and elongation during chromosome replication
FE003_RS06795	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FE003_RS06805	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FE003_RS06810	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FE003_RS06835	COG0726	polysaccharide deacetylase
FE003_RS06835	COG1649	PFAM Uncharacterised BCR, COG1649
FE003_RS06840	COG1215	transferase activity, transferring glycosyl groups
FE003_RS06845	COG3658	cytochrome
FE003_RS06855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE003_RS06875	COG0583	DNA-binding transcription factor activity
FE003_RS06895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE003_RS06900	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FE003_RS06915	COG1960	acyl-CoA dehydrogenase activity
FE003_RS06920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE003_RS06925	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE003_RS06950	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FE003_RS06955	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FE003_RS06965	COG2205	protein histidine kinase activity
FE003_RS06970	COG0745	RESPONSE REGULATOR receiver
FE003_RS06975	COG0174	glutamine synthetase
FE003_RS06995	COG0729	surface antigen
FE003_RS07025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE003_RS07030	COG2814	Major facilitator Superfamily
FE003_RS07045	COG0583	DNA-binding transcription factor activity
FE003_RS07060	COG1187	pseudouridine synthase activity
FE003_RS07080	COG0802	atpase or kinase
FE003_RS07085	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FE003_RS07095	COG1923	regulation of RNA biosynthetic process
FE003_RS07100	COG0697	spore germination
FE003_RS07115	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE003_RS07125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE003_RS07130	COG0519	Catalyzes the synthesis of GMP from XMP
FE003_RS07130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE003_RS07135	COG4302	ethanolamine ammonia-lyase activity
FE003_RS07140	COG4303	Ethanolamine ammonia lyase large subunit
FE003_RS07145	COG0531	amino acid
FE003_RS07165	COG1454	alcohol dehydrogenase
FE003_RS07170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE003_RS07180	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FE003_RS07200	COG0308	aminopeptidase N
FE003_RS07210	COG4221	oxidoreductase activity
FE003_RS07220	COG1605	Chorismate mutase
FE003_RS07240	COG1309	transcriptional regulator
FE003_RS07250	COG0668	transmembrane transport
FE003_RS07280	COG4773	Receptor
FE003_RS07300	COG0488	(ABC) transporter
FE003_RS07305	COG0589	response to stress
FE003_RS07320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FE003_RS07330	COG3135	benzoate transporter
FE003_RS07335	COG1522	sequence-specific DNA binding
FE003_RS07345	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FE003_RS07350	COG0583	DNA-binding transcription factor activity
FE003_RS07360	COG0183	Belongs to the thiolase family
FE003_RS07370	COG2030	dehydratase
FE003_RS07375	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FE003_RS07390	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FE003_RS07400	COG0824	Thioesterase
FE003_RS07405	COG1454	alcohol dehydrogenase
FE003_RS07415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FE003_RS07435	COG0069	glutamate synthase activity
FE003_RS07775	COG2814	Major facilitator Superfamily
FE003_RS07790	COG0511	ligase activity, forming carbon-carbon bonds
FE003_RS07810	COG1116	anion transmembrane transporter activity
FE003_RS07810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FE003_RS07815	COG0745	RESPONSE REGULATOR receiver
FE003_RS07825	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE003_RS07825	COG2146	nitrite reductase [NAD(P)H] activity
FE003_RS07830	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE003_RS07835	COG0243	molybdopterin cofactor binding
FE003_RS07845	COG0243	molybdopterin cofactor binding
FE003_RS07850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FE003_RS07865	COG0315	cyclic pyranopterin monophosphate synthase activity
FE003_RS07865	COG0521	Mo-molybdopterin cofactor biosynthetic process
FE003_RS07870	COG0303	'Molybdopterin
FE003_RS07880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE003_RS07885	COG0697	spore germination
FE003_RS07905	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FE003_RS07910	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FE003_RS07980	COG2204	response regulator
FE003_RS07985	COG3852	Histidine kinase
FE003_RS08010	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FE003_RS08015	COG0575	Belongs to the CDS family
FE003_RS08050	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE003_RS08065	COG2137	regulation of response to DNA damage stimulus
FE003_RS08075	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FE003_RS08080	COG1011	Hydrolase
FE003_RS08105	COG1522	sequence-specific DNA binding
FE003_RS08115	COG1113	amino acid transport
FE003_RS08130	COG0659	secondary active sulfate transmembrane transporter activity
FE003_RS08135	COG2135	peptidase activity
FE003_RS08150	COG3300	MHYT domain
FE003_RS08150	COG5001	Diguanylate cyclase
FE003_RS08175	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE003_RS08175	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FE003_RS08175	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FE003_RS08180	COG1105	Belongs to the carbohydrate kinase PfkB family
FE003_RS08185	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE003_RS08185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FE003_RS08215	COG0024	Methionine aminopeptidase
FE003_RS08220	COG0583	DNA-binding transcription factor activity
FE003_RS08230	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FE003_RS08235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FE003_RS08240	COG0516	GMP reductase activity
FE003_RS08240	COG0517	IMP dehydrogenase activity
FE003_RS08265	COG0552	protein localization to endoplasmic reticulum
FE003_RS08275	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FE003_RS08290	COG4890	Cyd operon protein YbgT
FE003_RS08295	COG1294	oxidase, subunit
FE003_RS08315	COG1585	Membrane protein implicated in regulation of membrane protease activity
FE003_RS08325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FE003_RS08330	COG4774	siderophore transport
FE003_RS08345	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FE003_RS08350	COG0569	domain protein
FE003_RS08355	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FE003_RS08385	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FE003_RS08390	COG0542	response to heat
FE003_RS08415	COG1902	pentaerythritol trinitrate reductase activity
FE003_RS08415	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE003_RS08460	COG2323	membrane
FE003_RS08465	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FE003_RS08475	COG2826	transposase and inactivated derivatives, IS30 family
FE003_RS08480	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FE003_RS08485	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FE003_RS08490	COG0183	Belongs to the thiolase family
FE003_RS08495	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FE003_RS08500	COG0596	Alpha beta hydrolase
FE003_RS08505	COG2271	Major facilitator Superfamily
FE003_RS08510	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE003_RS08515	COG3485	protocatechuate 3,4-dioxygenase
FE003_RS08520	COG3485	protocatechuate 3,4-dioxygenase
FE003_RS08525	COG0710	3-dehydroquinate dehydratase activity
FE003_RS08530	COG3420	alginic acid biosynthetic process
FE003_RS08535	COG3659	wide pore channel activity
FE003_RS08540	COG4993	Dehydrogenase
FE003_RS08550	COG2391	methyltransferase activity
FE003_RS08565	COG1414	Transcriptional regulator
FE003_RS08570	COG0583	DNA-binding transcription factor activity
FE003_RS08575	COG1960	acyl-CoA dehydrogenase activity
FE003_RS08600	COG2814	Major facilitator Superfamily
FE003_RS08610	COG0154	amidase activity
FE003_RS08630	COG4638	Rieske (2fe-2S)
FE003_RS08640	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS08650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE003_RS08660	COG3733	amine oxidase
FE003_RS08670	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS08680	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE003_RS08685	COG0183	Belongs to the thiolase family
FE003_RS08690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FE003_RS08695	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FE003_RS08705	COG4829	muconolactone delta-isomerase
FE003_RS08710	COG4948	Mandelate Racemase Muconate Lactonizing
FE003_RS08715	COG0583	DNA-binding transcription factor activity
FE003_RS08725	COG2186	Transcriptional regulator
FE003_RS08745	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS08765	COG1960	acyl-CoA dehydrogenase activity
FE003_RS08770	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS08775	COG3829	transcription factor binding
FE003_RS08785	COG3162	membrane
FE003_RS08800	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS08815	COG0753	catalase activity
FE003_RS08840	COG1846	Transcriptional regulator
FE003_RS08845	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE003_RS08845	COG1902	pentaerythritol trinitrate reductase activity
FE003_RS08865	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FE003_RS08895	COG1309	transcriptional regulator
FE003_RS08905	COG1335	isochorismatase
FE003_RS08910	COG0583	DNA-binding transcription factor activity
FE003_RS08920	COG0475	glutathione-regulated potassium exporter activity
FE003_RS08920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FE003_RS08930	COG1473	amidohydrolase
FE003_RS08945	COG2831	hemolysin activation secretion protein
FE003_RS08950	COG3210	domain, Protein
FE003_RS08980	COG2188	Transcriptional regulator
FE003_RS08995	COG0583	DNA-binding transcription factor activity
FE003_RS09025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE003_RS09045	COG1566	PFAM secretion protein HlyD family protein
FE003_RS09060	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS09065	COG0129	dihydroxy-acid dehydratase activity
FE003_RS09075	COG0583	DNA-binding transcription factor activity
FE003_RS09080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FE003_RS09090	COG2084	Dehydrogenase
FE003_RS09095	COG2207	Transcriptional regulator
FE003_RS09110	COG1064	alcohol dehydrogenase
FE003_RS09120	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FE003_RS09125	COG1120	ATPase activity
FE003_RS09145	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FE003_RS09265	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FE003_RS09320	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS09335	COG2207	Transcriptional regulator
FE003_RS09345	COG2205	protein histidine kinase activity
FE003_RS09350	COG0745	RESPONSE REGULATOR receiver
FE003_RS09355	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE003_RS09360	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE003_RS09365	COG1538	Outer membrane efflux protein
FE003_RS09375	COG2072	flavoprotein involved in K transport
FE003_RS09395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE003_RS09415	COG3539	Fimbrial protein
FE003_RS09445	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FE003_RS09455	COG0753	catalase activity
FE003_RS09470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FE003_RS09535	COG3433	isochorismatase activity
FE003_RS09535	COG1535	isochorismatase
FE003_RS09540	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS09545	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FE003_RS09550	COG4149	molybdate abc transporter
FE003_RS09555	COG0725	ABC transporter, periplasmic molybdate-binding protein
FE003_RS09565	COG4638	Rieske (2fe-2S)
FE003_RS09570	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FE003_RS09575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE003_RS09575	COG0543	2 iron, 2 sulfur cluster binding
FE003_RS09600	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS09615	COG2207	Transcriptional regulator
FE003_RS09625	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS09630	COG2610	gluconate transmembrane transporter activity
FE003_RS09640	COG0583	DNA-binding transcription factor activity
FE003_RS09650	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FE003_RS09655	COG2031	fatty acid transporter
FE003_RS09660	COG0183	Belongs to the thiolase family
FE003_RS09665	COG0583	DNA-binding transcription factor activity
FE003_RS09670	COG0583	DNA-binding transcription factor activity
FE003_RS09685	COG1027	Aspartate ammonia-lyase
FE003_RS09695	COG0477	Major facilitator Superfamily
FE003_RS09715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE003_RS09720	COG4521	taurine ABC transporter
FE003_RS09735	COG2188	Transcriptional regulator
FE003_RS09745	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FE003_RS09750	COG1733	regulation of RNA biosynthetic process
FE003_RS09755	COG2207	Transcriptional regulator
FE003_RS09755	COG3708	Transcriptional regulator
FE003_RS09770	COG0730	response to heat
FE003_RS09780	COG3453	Protein conserved in bacteria
FE003_RS09780	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE003_RS09790	COG3781	membrane
FE003_RS09795	COG1063	alcohol dehydrogenase
FE003_RS09805	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FE003_RS09810	COG0508	dehydrogenase complex catalyzes the overall conversion of
FE003_RS09815	COG0022	dehydrogenase e1 component
FE003_RS09820	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FE003_RS09825	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FE003_RS09840	COG3706	GGDEF domain
FE003_RS09855	COG0133	tryptophan synthase activity
FE003_RS09865	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FE003_RS09900	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FE003_RS09925	COG2226	methyltransferase
FE003_RS09980	COG0842	Transport permease protein
FE003_RS09985	COG0842	Transport permease protein
FE003_RS09990	COG1131	(ABC) transporter
FE003_RS10005	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FE003_RS10010	COG4773	Receptor
FE003_RS10030	COG0730	response to heat
FE003_RS10035	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FE003_RS10055	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FE003_RS10115	COG4264	IucA IucC family
FE003_RS10120	COG4264	IucA IucC family
FE003_RS10140	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FE003_RS10155	COG1960	acyl-CoA dehydrogenase activity
FE003_RS10160	COG1960	acyl-CoA dehydrogenase activity
FE003_RS10165	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FE003_RS10170	COG2207	Transcriptional regulator
FE003_RS10175	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE003_RS10180	COG0776	regulation of translation
FE003_RS10205	COG0822	iron-sulfur transferase activity
FE003_RS10210	COG0316	Belongs to the HesB IscA family
FE003_RS10240	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FE003_RS10260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FE003_RS10265	COG0702	epimerase
FE003_RS10300	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FE003_RS10310	COG0339	signal peptide processing
FE003_RS10360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FE003_RS10415	COG0739	heme binding
FE003_RS10415	COG0741	lytic transglycosylase activity
FE003_RS10415	COG1196	nuclear chromosome segregation
FE003_RS10470	COG4695	Portal protein
FE003_RS10540	COG0305	Participates in initiation and elongation during chromosome replication
FE003_RS10610	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FE003_RS10650	COG0776	regulation of translation
FE003_RS10715	COG0084	hydrolase, TatD family'
FE003_RS10735	COG1663	tetraacyldisaccharide 4'-kinase activity
FE003_RS10740	COG1132	(ABC) transporter
FE003_RS10750	COG0811	peptide transport
FE003_RS10755	COG1475	DNA binding
FE003_RS10760	COG1192	Involved in chromosome partitioning
FE003_RS10770	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FE003_RS10785	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FE003_RS10790	COG0191	fructose-bisphosphate aldolase activity
FE003_RS10810	COG0424	maF-like protein
FE003_RS10815	COG2850	peptidyl-arginine hydroxylation
FE003_RS10825	COG0640	Transcriptional regulator
FE003_RS10835	COG3619	membrane
FE003_RS10840	COG3122	Protein conserved in bacteria
FE003_RS10845	COG1132	(ABC) transporter
FE003_RS10865	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FE003_RS10870	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FE003_RS10880	COG0506	proline dehydrogenase activity
FE003_RS10880	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FE003_RS10880	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FE003_RS10885	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FE003_RS10900	COG3698	Phosphodiester glycosidase
FE003_RS10910	COG2353	YceI-like domain
FE003_RS10920	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FE003_RS10970	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FE003_RS10970	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FE003_RS10995	COG3539	Fimbrial protein
FE003_RS11000	COG3121	Chaperone
FE003_RS11030	COG0697	spore germination
FE003_RS11040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FE003_RS11050	COG0583	DNA-binding transcription factor activity
FE003_RS11070	COG1309	transcriptional regulator
FE003_RS11085	COG1522	sequence-specific DNA binding
FE003_RS11095	COG1126	abc transporter atp-binding protein
FE003_RS11100	COG0765	amino acid transport
FE003_RS11105	COG0765	amino acid transport
FE003_RS11135	COG1464	Belongs to the NlpA lipoprotein family
FE003_RS11145	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FE003_RS11150	COG2011	ABC-type metal ion transport system permease component
FE003_RS11155	COG0012	GTP binding
FE003_RS11180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FE003_RS11220	COG0386	Belongs to the glutathione peroxidase family
FE003_RS11230	COG0436	Aminotransferase
FE003_RS11270	COG3634	alkyl hydroperoxide reductase activity
FE003_RS11285	COG0583	DNA-binding transcription factor activity
FE003_RS11290	COG0798	PFAM Bile acid sodium symporter
FE003_RS11295	COG0640	Transcriptional regulator
FE003_RS11310	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FE003_RS11320	COG0583	DNA-binding transcription factor activity
FE003_RS11330	COG1953	Uracil, thiamine, allantoin
FE003_RS11340	COG2175	clavaminate synthase activity
FE003_RS11345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE003_RS11350	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FE003_RS11355	COG4521	taurine ABC transporter
FE003_RS11365	COG0477	Major facilitator Superfamily
FE003_RS11390	COG1271	oxidase subunit
FE003_RS11395	COG1294	oxidase, subunit
FE003_RS11405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE003_RS11425	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FE003_RS11445	COG3052	prosthetic group binding
FE003_RS11450	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FE003_RS11460	COG2814	Major facilitator Superfamily
FE003_RS11480	COG1346	cytolysis
FE003_RS11490	COG0583	DNA-binding transcription factor activity
FE003_RS11495	COG0625	glutathione transferase activity
FE003_RS11500	COG0625	glutathione transferase activity
FE003_RS11505	COG0583	DNA-binding transcription factor activity
FE003_RS11520	COG1045	serine acetyltransferase
FE003_RS11525	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FE003_RS11530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FE003_RS11540	COG1280	lysine exporter protein (LysE YggA)
FE003_RS11555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE003_RS11560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE003_RS11565	COG1126	abc transporter atp-binding protein
FE003_RS11570	COG0765	amino acid transport
FE003_RS11575	COG0765	amino acid transport
FE003_RS11595	COG2205	protein histidine kinase activity
FE003_RS11595	COG0784	Response regulator, receiver
FE003_RS11615	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FE003_RS11635	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS11680	COG0583	DNA-binding transcription factor activity
FE003_RS11700	COG0318	PFAM AMP-dependent synthetase and ligase
FE003_RS11705	COG1309	transcriptional regulator
FE003_RS11710	COG1960	acyl-CoA dehydrogenase activity
FE003_RS11715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FE003_RS11720	COG1024	Enoyl-CoA hydratase
FE003_RS11725	COG4770	biotin carboxylase activity
FE003_RS11735	COG0583	DNA-binding transcription factor activity
FE003_RS11750	COG1960	acyl-CoA dehydrogenase activity
FE003_RS11760	COG2814	Major facilitator Superfamily
FE003_RS11770	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FE003_RS11775	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FE003_RS11780	COG2814	Major facilitator Superfamily
FE003_RS11785	COG1960	acyl-CoA dehydrogenase activity
FE003_RS11790	COG1024	Enoyl-CoA hydratase
FE003_RS11795	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS11800	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE003_RS11805	COG0183	Belongs to the thiolase family
FE003_RS11815	COG2814	Major facilitator Superfamily
FE003_RS11825	COG1024	Enoyl-CoA hydratase
FE003_RS11840	COG1960	acyl-CoA dehydrogenase activity
FE003_RS11845	COG2814	Major facilitator Superfamily
FE003_RS11850	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FE003_RS11855	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FE003_RS11870	COG3842	ATPase activity
FE003_RS11875	COG1840	ABC-type Fe3 transport system, periplasmic component
FE003_RS11885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE003_RS11890	COG1414	Transcriptional regulator
FE003_RS11900	COG0583	DNA-binding transcription factor activity
FE003_RS11905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FE003_RS11910	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS11920	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FE003_RS11930	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS11935	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE003_RS11940	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE003_RS11945	COG2267	carboxylic ester hydrolase activity
FE003_RS11965	COG3038	cytochrome b561
FE003_RS11970	COG0753	catalase activity
FE003_RS12010	COG2050	protein possibly involved in aromatic compounds catabolism
FE003_RS12020	COG3327	negative regulation of DNA-templated transcription, initiation
FE003_RS12025	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FE003_RS12030	COG0183	Belongs to the thiolase family
FE003_RS12035	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE003_RS12040	COG1024	Enoyl-CoA hydratase
FE003_RS12045	COG1024	Enoyl-CoA hydratase
FE003_RS12050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FE003_RS12055	COG2151	metal-sulfur cluster biosynthetic enzyme
FE003_RS12060	COG3396	Phenylacetate-CoA oxygenase
FE003_RS12065	COG3460	Phenylacetate-CoA oxygenase
FE003_RS12070	COG3396	Phenylacetate-CoA oxygenase
FE003_RS12075	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS12075	COG2030	dehydratase
FE003_RS12080	COG1760	l-serine dehydratase
FE003_RS12085	COG0531	amino acid
FE003_RS12090	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS12105	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE003_RS12115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FE003_RS12135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE003_RS12150	COG0789	Transcriptional regulator
FE003_RS12165	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FE003_RS12180	COG2807	transmembrane transport
FE003_RS12185	COG0590	tRNA wobble adenosine to inosine editing
FE003_RS12290	COG2826	transposase and inactivated derivatives, IS30 family
FE003_RS12310	COG1116	anion transmembrane transporter activity
FE003_RS12315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FE003_RS12325	COG0864	Transcriptional regulator
FE003_RS12345	COG2249	NAD(P)H dehydrogenase (quinone) activity
FE003_RS12350	COG0439	Biotin carboxylase
FE003_RS12365	COG1063	alcohol dehydrogenase
FE003_RS12375	COG1309	transcriptional regulator
FE003_RS12400	COG0038	chloride channel
FE003_RS12405	COG4770	biotin carboxylase activity
FE003_RS12425	COG1914	H( )-stimulated, divalent metal cation uptake system
FE003_RS12430	COG0583	DNA-binding transcription factor activity
FE003_RS12485	COG1250	3-hydroxyacyl-CoA dehydrogenase
FE003_RS12505	COG2814	Major facilitator Superfamily
FE003_RS12520	COG1560	Kdo2-lipid A biosynthetic process
FE003_RS12530	COG2826	transposase and inactivated derivatives, IS30 family
FE003_RS12535	COG5006	permease, DMT superfamily
FE003_RS12540	COG1522	sequence-specific DNA binding
FE003_RS12555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FE003_RS12565	COG4122	O-methyltransferase activity
FE003_RS12595	COG1538	Outer membrane efflux protein
FE003_RS12600	COG1137	ATPase activity
FE003_RS12605	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FE003_RS12615	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FE003_RS12620	COG0517	IMP dehydrogenase activity
FE003_RS12620	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FE003_RS12885	COG2814	Major facilitator Superfamily
FE003_RS12925	COG1278	Cold shock
FE003_RS12930	COG1280	lysine exporter protein (LysE YggA)
FE003_RS12965	COG1570	exodeoxyribonuclease VII activity
FE003_RS13020	COG0583	DNA-binding transcription factor activity
FE003_RS13025	COG4638	Rieske (2fe-2S)
FE003_RS13030	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FE003_RS13035	COG0633	Ferredoxin
FE003_RS13035	COG0543	2 iron, 2 sulfur cluster binding
FE003_RS13040	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS13045	COG3135	benzoate transporter
FE003_RS13050	COG2814	Major facilitator Superfamily
FE003_RS13065	COG1643	Atp-dependent helicase
FE003_RS13070	COG0450	alkyl hydroperoxide reductase
FE003_RS13080	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FE003_RS13090	COG3634	alkyl hydroperoxide reductase activity
FE003_RS13110	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FE003_RS13115	COG0625	glutathione transferase activity
FE003_RS13125	COG2885	chlorophyll binding
FE003_RS13160	COG0542	response to heat
FE003_RS13175	COG1765	OsmC-like protein
FE003_RS13190	COG0667	Aldo Keto reductase
FE003_RS13205	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FE003_RS13215	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FE003_RS13225	COG0527	aspartate kinase activity
FE003_RS13235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FE003_RS13245	COG3038	cytochrome b561
FE003_RS13250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FE003_RS13255	COG2252	PERMEase
FE003_RS13265	COG2072	flavoprotein involved in K transport
FE003_RS13280	COG1741	Belongs to the pirin family
FE003_RS13285	COG1309	transcriptional regulator
FE003_RS13295	COG0300	oxidoreductase activity
FE003_RS13320	COG5001	Diguanylate cyclase
FE003_RS13345	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE003_RS13435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FE003_RS13515	COG1192	Involved in chromosome partitioning
FE003_RS13535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE003_RS13605	COG1349	DNA-binding transcription factor activity
FE003_RS13615	COG2084	Dehydrogenase
FE003_RS13655	COG4269	membrane
FE003_RS13670	COG1902	pentaerythritol trinitrate reductase activity
FE003_RS13670	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE003_RS13680	COG5001	Diguanylate cyclase
FE003_RS13680	COG4251	negative regulation of phosphorylation
FE003_RS13680	COG3706	GGDEF domain
FE003_RS13680	COG2203	Gaf domain
FE003_RS13690	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE003_RS13710	COG4172	Belongs to the ABC transporter superfamily
FE003_RS13715	COG4239	(ABC) transporter, permease
FE003_RS13720	COG4174	ABC transporter (Permease)
FE003_RS13730	COG0741	lytic transglycosylase activity
FE003_RS13730	COG1388	LysM domain
FE003_RS13730	COG0741	lytic transglycosylase activity
FE003_RS13730	COG1388	LysM domain
FE003_RS13735	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FE003_RS13775	COG0583	DNA-binding transcription factor activity
FE003_RS13780	COG1279	arginine transmembrane transporter activity
FE003_RS13800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE003_RS13805	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE003_RS13810	COG0006	proline dipeptidase activity
FE003_RS13845	COG2194	sulfuric ester hydrolase activity
FE003_RS13890	COG0739	heme binding
FE003_RS14215	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FE003_RS14245	COG3384	dioxygenase
FE003_RS14255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FE003_RS14260	COG2878	Part of a membrane complex involved in electron transport
FE003_RS14265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FE003_RS14290	COG0768	penicillin binding
FE003_RS14295	COG0742	ribosomal rna small subunit methyltransferase
FE003_RS14310	COG0830	nickel cation binding
FE003_RS14320	COG0804	urea catabolic process
FE003_RS14360	COG1253	flavin adenine dinucleotide binding
FE003_RS14370	COG2851	Citrate transporter
FE003_RS14420	COG1773	rubredoxin
FE003_RS14425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FE003_RS14435	COG0583	DNA-binding transcription factor activity
FE003_RS14460	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FE003_RS14465	COG4181	ATPase activity
FE003_RS14510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FE003_RS14530	COG0306	phosphate transporter
FE003_RS14540	COG3958	Transketolase
FE003_RS14545	COG3959	Transketolase, thiamine diphosphate binding domain
FE003_RS14550	COG2271	Major facilitator Superfamily
FE003_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS14560	COG0583	DNA-binding transcription factor activity
FE003_RS14580	COG2223	nitrite transmembrane transporter activity
FE003_RS14585	COG2207	Transcriptional regulator
FE003_RS14590	COG2066	Belongs to the glutaminase family
FE003_RS14595	COG0242	peptide deformylase activity
FE003_RS14600	COG0477	Major facilitator Superfamily
FE003_RS14610	COG0028	Belongs to the TPP enzyme family
FE003_RS14625	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS14630	COG2267	carboxylic ester hydrolase activity
FE003_RS14640	COG2271	Major facilitator Superfamily
FE003_RS14645	COG0446	pyridine nucleotide-disulphide oxidoreductase
FE003_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS14675	COG1414	Transcriptional regulator
FE003_RS14690	COG1024	Enoyl-CoA hydratase
FE003_RS14700	COG1215	transferase activity, transferring glycosyl groups
FE003_RS14705	COG1649	PFAM Uncharacterised BCR, COG1649
FE003_RS14705	COG0726	polysaccharide deacetylase
FE003_RS14715	COG4681	YaeQ
FE003_RS14725	COG0523	cobalamin synthesis protein
FE003_RS14735	COG1607	acyl-coa hydrolase
FE003_RS14745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FE003_RS14750	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FE003_RS14755	COG1309	transcriptional regulator
FE003_RS14780	COG2040	homocysteine
FE003_RS14785	COG0531	amino acid
FE003_RS14810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE003_RS14815	COG0477	Major facilitator Superfamily
FE003_RS14885	COG0629	single-stranded DNA binding
FE003_RS14930	COG0582	viral genome integration into host DNA
FE003_RS14940	COG0405	Gamma-glutamyltransferase
FE003_RS14945	COG2814	Major facilitator Superfamily
FE003_RS14955	COG2050	protein possibly involved in aromatic compounds catabolism
FE003_RS14970	COG1090	epimerase
FE003_RS14990	COG0420	3'-5' exonuclease activity
FE003_RS15015	COG0735	belongs to the Fur family
FE003_RS15020	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FE003_RS15045	COG0121	glutamine amidotransferase
FE003_RS15060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE003_RS15070	COG0210	DNA helicase
FE003_RS15075	COG2885	chlorophyll binding
FE003_RS15080	COG0204	Acyl-transferase
FE003_RS15095	COG2894	cell division
FE003_RS15125	COG1280	lysine exporter protein (LysE YggA)
FE003_RS15130	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FE003_RS15130	COG1674	ftsk spoiiie
FE003_RS15135	COG0492	ferredoxin-NADP+ reductase activity
FE003_RS15140	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FE003_RS15150	COG0456	acetyltransferase
FE003_RS15195	COG1981	membrane
FE003_RS15210	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE003_RS15210	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FE003_RS15230	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS15240	COG0657	acetylesterase activity
FE003_RS15250	COG0473	3-isopropylmalate dehydrogenase activity
FE003_RS15255	COG0583	DNA-binding transcription factor activity
FE003_RS15275	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FE003_RS15300	COG0564	pseudouridine synthase activity
FE003_RS15310	COG0358	DNA primase activity
FE003_RS15325	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FE003_RS15355	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FE003_RS15385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FE003_RS15395	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FE003_RS15395	COG0351	phosphomethylpyrimidine kinase
FE003_RS15395	COG0352	thiamine-phosphate diphosphorylase activity
FE003_RS15400	COG1652	LysM domain
FE003_RS15425	COG1399	metal-binding, possibly nucleic acid-binding protein
FE003_RS15430	COG3101	peptidyl-lysine hydroxylation
FE003_RS15435	COG0009	L-threonylcarbamoyladenylate synthase
FE003_RS15440	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FE003_RS15445	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FE003_RS15460	COG4106	trans-aconitate 2-methyltransferase activity
FE003_RS15475	COG2226	methyltransferase
FE003_RS15475	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE003_RS15475	COG0596	Alpha beta hydrolase
FE003_RS15480	COG1877	trehalose-phosphatase activity
FE003_RS15485	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FE003_RS15490	COG2223	nitrite transmembrane transporter activity
FE003_RS15510	COG1196	nuclear chromosome segregation
FE003_RS15520	COG0730	response to heat
FE003_RS15535	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FE003_RS15545	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE003_RS15605	COG0489	protein tyrosine kinase activity
FE003_RS15615	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE003_RS15615	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE003_RS15645	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FE003_RS15650	COG2081	HI0933 family
FE003_RS15660	COG0668	transmembrane transport
FE003_RS15680	COG0583	DNA-binding transcription factor activity
FE003_RS15700	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FE003_RS15705	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE003_RS15735	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FE003_RS15775	COG0745	RESPONSE REGULATOR receiver
FE003_RS15795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE003_RS15810	COG2826	transposase and inactivated derivatives, IS30 family
FE003_RS15820	COG2826	transposase and inactivated derivatives, IS30 family
FE003_RS15905	COG4993	Dehydrogenase
FE003_RS15925	COG0384	phenazine biosynthesis protein PhzF
FE003_RS15955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FE003_RS15970	COG0583	DNA-binding transcription factor activity
FE003_RS16000	COG0583	DNA-binding transcription factor activity
FE003_RS16020	COG0583	DNA-binding transcription factor activity
FE003_RS16025	COG1053	succinate dehydrogenase
FE003_RS16035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FE003_RS16040	COG2814	Major facilitator Superfamily
FE003_RS16045	COG1960	acyl-CoA dehydrogenase activity
FE003_RS16050	COG0583	DNA-binding transcription factor activity
FE003_RS16055	COG1063	alcohol dehydrogenase
FE003_RS16085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FE003_RS16090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FE003_RS16095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FE003_RS16110	COG3667	copper resistance
FE003_RS16115	COG2132	Multicopper oxidase
FE003_RS16125	COG0561	phosphatase activity
FE003_RS16130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FE003_RS16155	COG1214	PFAM Peptidase M22, glycoprotease
FE003_RS16205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FE003_RS16215	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FE003_RS16220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FE003_RS16225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FE003_RS16290	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FE003_RS16300	COG1846	Transcriptional regulator
FE003_RS16305	COG1764	response to oxidative stress
FE003_RS16345	COG0037	tRNA processing
FE003_RS16355	COG0248	Ppx GppA phosphatase
FE003_RS16385	COG0072	phenylalanine-tRNA ligase activity
FE003_RS16425	COG1238	metal cluster binding
FE003_RS16430	COG0625	glutathione transferase activity
FE003_RS16450	COG0318	PFAM AMP-dependent synthetase and ligase
FE003_RS16455	COG3028	Belongs to the UPF0307 family
FE003_RS16460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FE003_RS16480	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FE003_RS16485	COG0617	tRNA 3'-terminal CCA addition
FE003_RS16490	COG1555	photosystem II stabilization
FE003_RS16495	COG3956	TIGRFAM MazG family protein
FE003_RS16505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FE003_RS16525	COG5002	protein histidine kinase activity
FE003_RS16525	COG2205	protein histidine kinase activity
FE003_RS16525	COG0784	Response regulator, receiver
FE003_RS16530	COG1024	Enoyl-CoA hydratase
FE003_RS16535	COG2084	Dehydrogenase
FE003_RS16540	COG3622	Belongs to the hyi family
FE003_RS16570	COG0697	spore germination
FE003_RS16580	COG2814	Major facilitator Superfamily
FE003_RS16585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FE003_RS16595	COG0583	DNA-binding transcription factor activity
FE003_RS16605	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FE003_RS16620	COG0084	hydrolase, TatD family'
FE003_RS16635	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FE003_RS16670	COG0440	acetolactate synthase activity
FE003_RS16675	COG0028	Belongs to the TPP enzyme family
FE003_RS16700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FE003_RS16705	COG1136	(ABC) transporter
FE003_RS16705	COG0577	efflux transmembrane transporter activity
FE003_RS16710	COG1538	Outer membrane efflux protein
FE003_RS16725	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FE003_RS16730	COG1162	GTPase activity
FE003_RS16740	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FE003_RS16760	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FE003_RS16765	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS16805	COG2986	histidine ammonia-lyase
FE003_RS16820	COG0318	PFAM AMP-dependent synthetase and ligase
FE003_RS16835	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE003_RS16880	COG1426	Protein conserved in bacteria
FE003_RS16925	COG0793	Belongs to the peptidase S41A family
FE003_RS16940	COG2267	carboxylic ester hydrolase activity
FE003_RS16950	COG1012	belongs to the aldehyde dehydrogenase family
FE003_RS16955	COG3265	gluconokinase activity
FE003_RS16965	COG0800	Aldolase
FE003_RS16975	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FE003_RS16980	COG0857	belongs to the CobB CobQ family
FE003_RS16980	COG0280	phosphate acetyltransferase
FE003_RS16985	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FE003_RS16985	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FE003_RS17005	COG0740	serine-type endopeptidase activity
FE003_RS17015	COG4774	siderophore transport
FE003_RS17025	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FE003_RS17035	COG2813	Specifically methylates the guanine in position
FE003_RS17035	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FE003_RS17135	COG0788	formyltetrahydrofolate deformylase activity
FE003_RS17160	COG4651	solute:proton antiporter activity
FE003_RS17160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FE003_RS17180	COG0724	RNA recognition motif
FE003_RS17185	COG0210	DNA helicase
FE003_RS17210	COG1733	regulation of RNA biosynthetic process
FE003_RS17220	COG2900	Belongs to the SlyX family
FE003_RS17225	COG0488	(ABC) transporter
FE003_RS17230	COG1280	lysine exporter protein (LysE YggA)
FE003_RS17235	COG1560	Kdo2-lipid A biosynthetic process
FE003_RS17245	COG1301	dicarboxylic acid transport
FE003_RS17300	COG0473	3-isopropylmalate dehydrogenase activity
FE003_RS17365	COG0583	DNA-binding transcription factor activity
FE003_RS17375	COG0625	glutathione transferase activity
FE003_RS17380	COG2378	regulation of single-species biofilm formation
FE003_RS17385	COG0546	phosphoglycolate phosphatase activity
FE003_RS17400	COG1530	ribonuclease E activity
FE003_RS17405	COG0318	PFAM AMP-dependent synthetase and ligase
FE003_RS17420	COG0583	DNA-binding transcription factor activity
FE003_RS17425	COG4221	oxidoreductase activity
FE003_RS17430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FE003_RS17440	COG0534	Mate efflux family protein
FE003_RS17455	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FE003_RS17495	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FE003_RS17500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FE003_RS17515	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FE003_RS17525	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FE003_RS17525	COG0644	oxidoreductase
FE003_RS17530	COG0425	Belongs to the sulfur carrier protein TusA family
FE003_RS17535	COG4535	Mg2 and Co2 transporter CorC
FE003_RS17545	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FE003_RS17565	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FE003_RS17570	COG0475	glutathione-regulated potassium exporter activity
FE003_RS17570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FE003_RS17575	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FE003_RS17580	COG2826	transposase and inactivated derivatives, IS30 family
FE003_RS17590	COG0484	heat shock protein binding
FE003_RS17595	COG0789	Transcriptional regulator
FE003_RS17600	COG0598	Magnesium transport protein CorA
FE003_RS17615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FE003_RS17620	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FE003_RS17625	COG1074	ATP-dependent DNA helicase activity
FE003_RS17630	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FE003_RS17650	COG2226	methyltransferase
FE003_RS17665	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FE003_RS17670	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FE003_RS17685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FE003_RS17685	COG2111	Na H antiporter
FE003_RS17690	COG1006	Multisubunit Na H antiporter MnhC subunit
FE003_RS17695	COG0651	ATP synthesis coupled electron transport
FE003_RS17700	COG1863	multisubunit Na H antiporter MnhE subunit
FE003_RS17705	COG2212	antiporter activity
FE003_RS17710	COG1320	monovalent cation:proton antiporter activity
FE003_RS17725	COG0195	Participates in both transcription termination and antitermination
FE003_RS17775	COG0237	dephospho-CoA kinase activity
FE003_RS17785	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FE003_RS17800	COG0497	DNA recombination
FE003_RS17810	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FE003_RS17840	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FE003_RS17840	COG2169	Transcriptional regulator
FE003_RS17845	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FE003_RS17915	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FE003_RS17930	COG0326	Molecular chaperone. Has ATPase activity
FE003_RS17945	COG2056	Na+-H+ antiporter family
FE003_RS17950	COG0596	Alpha beta hydrolase
FE003_RS18055	COG0546	phosphoglycolate phosphatase activity
FE003_RS18060	COG1716	ATPase activity
FE003_RS18105	COG0181	hydroxymethylbilane synthase activity
FE003_RS18115	COG3275	phosphorelay sensor kinase activity
FE003_RS18135	COG1538	Outer membrane efflux protein
FE003_RS18140	COG0697	spore germination
FE003_RS18165	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FE003_RS18170	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FE003_RS18175	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FE003_RS18180	COG0772	Belongs to the SEDS family
FE003_RS18205	COG4974	Belongs to the 'phage' integrase family
FE003_RS18210	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE003_RS18220	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FE003_RS18230	COG2197	response regulator
FE003_RS18245	COG0793	Belongs to the peptidase S41A family
FE003_RS18250	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FE003_RS18255	COG0795	lipopolysaccharide-transporting ATPase activity
FE003_RS18295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE003_RS18295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FE003_RS18305	COG0004	ammonium transporteR
FE003_RS18310	COG0347	Belongs to the P(II) protein family
FE003_RS18320	COG0606	chelatase, subunit chli
FE003_RS18375	COG0659	secondary active sulfate transmembrane transporter activity
FE003_RS18380	COG0589	response to stress
FE003_RS18420	COG0606	chelatase, subunit chli
FE003_RS18425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FE003_RS18435	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FE003_RS18450	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FE003_RS18465	COG0318	PFAM AMP-dependent synthetase and ligase
FE003_RS18475	COG0477	Major facilitator Superfamily
FE003_RS18480	COG2860	membrane
FE003_RS18490	COG1253	flavin adenine dinucleotide binding
FE003_RS18510	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FE003_RS18545	COG0655	NAD(P)H dehydrogenase (quinone) activity
FE003_RS18555	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FE003_RS18590	COG1309	transcriptional regulator
FE003_RS18625	COG0758	DNA mediated transformation
FE003_RS18635	COG0697	spore germination
FE003_RS18640	COG1309	transcriptional regulator
FE003_RS18655	COG0386	Belongs to the glutathione peroxidase family
FE003_RS18720	COG1121	(ABC) transporter
FE003_RS18725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FE003_RS18730	COG1280	lysine exporter protein (LysE YggA)
FE003_RS18735	COG2837	iron assimilation
FE003_RS18745	COG0281	malic enzyme
FE003_RS18790	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FE003_RS18790	COG0519	Catalyzes the synthesis of GMP from XMP
FE003_RS18795	COG4399	Belongs to the UPF0754 family
FE003_RS18800	COG2259	Doxx family
FE003_RS18805	COG0586	Pfam SNARE associated Golgi protein
FE003_RS18820	COG1192	Involved in chromosome partitioning
FE003_RS18830	COG0271	Belongs to the BolA IbaG family
FE003_RS18850	COG2267	carboxylic ester hydrolase activity
FE003_RS18870	COG3321	synthase
FE003_RS18870	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FE003_RS18870	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FE003_RS18870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FE003_RS18875	COG1960	acyl-CoA dehydrogenase activity
FE003_RS18885	COG2197	response regulator
FE003_RS18895	COG3916	Acyl-homoserine-lactone synthase
FE003_RS18900	COG0477	Major facilitator Superfamily
FE003_RS18905	COG1024	Enoyl-CoA hydratase
FE003_RS18910	COG1024	Enoyl-CoA hydratase
FE003_RS18915	COG1960	acyl-CoA dehydrogenase activity
FE003_RS18920	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FE003_RS18940	COG1113	amino acid transport
FE003_RS18945	COG1113	amino acid transport
FE003_RS18950	COG0251	oxidation-reduction process
FE003_RS18990	COG0564	pseudouridine synthase activity
FE003_RS19055	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FE003_RS19070	COG1802	Transcriptional regulator
FE003_RS19080	COG1448	Aminotransferase
FE003_RS19085	COG0277	FAD linked oxidase domain protein
FE003_RS19095	COG2186	Transcriptional regulator
FE003_RS19105	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FE003_RS19110	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FE003_RS19125	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FE003_RS19130	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FE003_RS19135	COG1216	Glycosyl transferase, family 2
FE003_RS19165	COG2089	acid synthase
FE003_RS19180	COG1083	cytidylyl-transferase
FE003_RS19185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FE003_RS19190	COG1086	Polysaccharide biosynthesis protein
FE003_RS19195	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FE003_RS19200	COG1596	polysaccharide export
FE003_RS19225	COG0728	peptidoglycan biosynthetic process
FE003_RS19230	COG3023	N-Acetylmuramoyl-L-alanine amidase
FE003_RS19285	COG0546	phosphoglycolate phosphatase activity
FE003_RS19290	COG1028	Short-chain dehydrogenase reductase Sdr
FE003_RS19310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FE003_RS19315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FE003_RS19320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FE003_RS19325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FE003_RS19330	COG1116	anion transmembrane transporter activity
FE003_RS19335	COG1309	transcriptional regulator
FE003_RS19340	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FE003_RS19350	COG0196	riboflavin kinase activity
FE003_RS19355	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FE003_RS19365	COG1047	Peptidyl-prolyl cis-trans
FE003_RS19405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FE003_RS19410	COG0657	acetylesterase activity
FE003_RS19460	COG2951	lytic endotransglycosylase activity
FE003_RS19465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FE003_RS19485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FE003_RS19495	COG0671	phosphoesterase, PA-phosphatase related
FE003_RS19500	COG0861	Integral membrane protein TerC family
FE003_RS19510	COG0754	glutathionylspermidine amidase activity
FE003_RS19520	COG0402	S-adenosylhomocysteine deaminase activity
FE003_RS19535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FE003_RS19540	COG1230	cation diffusion facilitator family transporter
FE003_RS19555	COG0706	membrane insertase activity
FE003_RS19670	COG0488	(ABC) transporter
FE003_RS19675	COG3173	Aminoglycoside phosphotransferase
FE003_RS19735	COG0756	dUTP diphosphatase activity
FE003_RS19760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE003_RS19765	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FE003_RS19765	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FE003_RS19790	COG0419	ATPase involved in DNA repair
FE003_RS19835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
FE003_RS19890	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FE003_RS19915	COG0194	GDP metabolic process
FE003_RS19955	COG0358	DNA primase activity
FE003_RS20005	COG0791	NLP P60 protein
FE003_RS20115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FE003_RS20120	COG1475	DNA binding
FE003_RS20265	COG2826	transposase and inactivated derivatives, IS30 family