locus-tag	class	description
FYA21_RS00015	COG2321	neutral zinc metallopeptidase
FYA21_RS00020	COG2354	Protein conserved in bacteria
FYA21_RS00040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA21_RS00065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FYA21_RS00070	COG1053	succinate dehydrogenase
FYA21_RS00075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FYA21_RS00080	COG2009	succinate dehydrogenase
FYA21_RS00120	COG2921	Belongs to the UPF0250 family
FYA21_RS00125	COG0321	lipoyl(octanoyl) transferase activity
FYA21_RS00140	COG0531	amino acid
FYA21_RS00150	COG1733	regulation of RNA biosynthetic process
FYA21_RS00155	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FYA21_RS00160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FYA21_RS00160	COG1648	precorrin-2 dehydrogenase activity
FYA21_RS00175	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FYA21_RS00205	COG0671	phosphoesterase, PA-phosphatase related
FYA21_RS00210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA21_RS00220	COG1538	Outer membrane efflux protein
FYA21_RS00225	COG0393	Putative heavy-metal-binding
FYA21_RS00230	COG0393	Putative heavy-metal-binding
FYA21_RS00240	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS00250	COG0525	valine-tRNA ligase activity
FYA21_RS00255	COG2226	methyltransferase
FYA21_RS00270	COG0583	DNA-binding transcription factor activity
FYA21_RS00280	COG0004	ammonium transporteR
FYA21_RS00290	COG0642	Histidine kinase
FYA21_RS00295	COG0745	RESPONSE REGULATOR receiver
FYA21_RS00300	COG2194	sulfuric ester hydrolase activity
FYA21_RS00320	COG1752	Esterase of the alpha-beta hydrolase superfamily
FYA21_RS00335	COG2315	Protein conserved in bacteria
FYA21_RS00340	COG0142	geranyltranstransferase activity
FYA21_RS00345	COG2828	Protein conserved in bacteria
FYA21_RS00350	COG1113	amino acid transport
FYA21_RS00370	COG2207	Transcriptional regulator
FYA21_RS00395	COG2249	NAD(P)H dehydrogenase (quinone) activity
FYA21_RS00405	COG0560	Phosphoserine phosphatase
FYA21_RS00415	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA21_RS00425	COG1530	ribonuclease E activity
FYA21_RS00430	COG0424	maF-like protein
FYA21_RS00435	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FYA21_RS00440	COG1792	Involved in formation and maintenance of cell shape
FYA21_RS00445	COG1077	Cell shape determining protein MreB Mrl
FYA21_RS00450	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA21_RS00460	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FYA21_RS00485	COG3590	peptidase
FYA21_RS00490	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FYA21_RS00495	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYA21_RS00500	COG1752	Esterase of the alpha-beta hydrolase superfamily
FYA21_RS00505	COG1115	amino acid carrier protein
FYA21_RS00525	COG2814	Major facilitator Superfamily
FYA21_RS00530	COG1289	transmembrane transporter activity
FYA21_RS00540	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FYA21_RS00580	COG1376	ErfK ybiS ycfS ynhG family protein
FYA21_RS00585	COG2832	Protein of unknown function (DUF454)
FYA21_RS00595	COG5510	response to toxic substance
FYA21_RS00620	COG0840	transmembrane signaling receptor activity
FYA21_RS00660	COG3422	double-strand break repair
FYA21_RS00665	COG2824	Alkylphosphonate utilization operon protein PhnA
FYA21_RS00670	COG3189	MarR family transcriptional regulator
FYA21_RS00675	COG0596	Alpha beta hydrolase
FYA21_RS00680	COG0778	Nitroreductase
FYA21_RS00685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA21_RS00690	COG1335	isochorismatase
FYA21_RS00695	COG0251	oxidation-reduction process
FYA21_RS00700	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA21_RS00705	COG2233	PERMEase
FYA21_RS00720	COG0354	folic acid binding
FYA21_RS00725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA21_RS00740	COG1902	pentaerythritol trinitrate reductase activity
FYA21_RS00745	COG4772	TonB-dependent receptor
FYA21_RS00750	COG2094	Belongs to the DNA glycosylase MPG family
FYA21_RS00775	COG1217	gtp-binding protein TYPA
FYA21_RS00780	COG2233	PERMEase
FYA21_RS00790	COG0833	amino acid
FYA21_RS00795	COG1690	Belongs to the RtcB family
FYA21_RS00805	COG2885	chlorophyll binding
FYA21_RS00805	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FYA21_RS00815	COG0183	Belongs to the thiolase family
FYA21_RS00835	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYA21_RS00855	COG2207	Transcriptional regulator
FYA21_RS00860	COG0183	Belongs to the thiolase family
FYA21_RS00875	COG4667	esterase of the alpha-beta hydrolase superfamily
FYA21_RS00890	COG1272	protein, Hemolysin III
FYA21_RS00895	COG0477	Major facilitator Superfamily
FYA21_RS00910	COG0450	alkyl hydroperoxide reductase
FYA21_RS00930	COG0285	dihydrofolate synthase activity
FYA21_RS00980	COG2096	Adenosyltransferase
FYA21_RS01000	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FYA21_RS01005	COG0745	RESPONSE REGULATOR receiver
FYA21_RS01010	COG2205	protein histidine kinase activity
FYA21_RS01020	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS01025	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS01090	COG0438	transferase activity, transferring glycosyl groups
FYA21_RS01095	COG0463	Glycosyl transferase, family 2
FYA21_RS01100	COG0726	polysaccharide deacetylase
FYA21_RS01120	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FYA21_RS01125	COG2205	protein histidine kinase activity
FYA21_RS01170	COG1862	Preprotein translocase
FYA21_RS01180	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FYA21_RS01185	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FYA21_RS01195	COG3781	membrane
FYA21_RS01200	COG0613	PHP domain protein
FYA21_RS01210	COG2350	Protein conserved in bacteria
FYA21_RS01240	COG1607	acyl-coa hydrolase
FYA21_RS01300	COG2199	diguanylate cyclase activity
FYA21_RS01310	COG1408	metallophosphoesterase
FYA21_RS01315	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA21_RS01325	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FYA21_RS01345	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FYA21_RS01350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FYA21_RS01355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FYA21_RS01365	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FYA21_RS01375	COG2969	positive regulation of protein catabolic process
FYA21_RS01395	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS01400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYA21_RS01415	COG1309	transcriptional regulator
FYA21_RS01420	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS01465	COG1183	phosphatidylcholine synthase activity
FYA21_RS01470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FYA21_RS01500	COG1196	nuclear chromosome segregation
FYA21_RS01500	COG0741	lytic transglycosylase activity
FYA21_RS01500	COG0739	heme binding
FYA21_RS01510	COG1702	phosphate starvation-inducible protein PhoH
FYA21_RS01545	COG1295	ribonuclease BN
FYA21_RS01550	COG0697	spore germination
FYA21_RS01555	COG2169	Transcriptional regulator
FYA21_RS01560	COG0179	Fumarylacetoacetate (FAA) hydrolase
FYA21_RS01605	COG0557	exoribonuclease II activity
FYA21_RS01610	COG0339	signal peptide processing
FYA21_RS01615	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FYA21_RS01645	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FYA21_RS01650	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS01805	COG0626	cystathionine gamma-synthase activity
FYA21_RS01820	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA21_RS01820	COG1017	nitric oxide dioxygenase activity
FYA21_RS01825	COG1959	2 iron, 2 sulfur cluster binding
FYA21_RS01840	COG1301	dicarboxylic acid transport
FYA21_RS01845	COG1946	Acyl-CoA thioesterase
FYA21_RS01865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FYA21_RS01870	COG1040	competence protein
FYA21_RS01875	COG0494	nUDIX hydrolase
FYA21_RS01885	COG0598	Magnesium transport protein CorA
FYA21_RS01895	COG2854	intermembrane phospholipid transfer
FYA21_RS01905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FYA21_RS01910	COG1127	ABC transporter
FYA21_RS01920	COG0513	Belongs to the DEAD box helicase family
FYA21_RS01940	COG0408	coproporphyrinogen oxidase activity
FYA21_RS01955	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS01965	COG1983	PspC domain protein
FYA21_RS01970	COG0517	IMP dehydrogenase activity
FYA21_RS02030	COG0583	DNA-binding transcription factor activity
FYA21_RS02070	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS02080	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA21_RS02085	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA21_RS02090	COG0833	amino acid
FYA21_RS02120	COG1192	Involved in chromosome partitioning
FYA21_RS02125	COG0628	permease
FYA21_RS02135	COG1289	transmembrane transporter activity
FYA21_RS02150	COG2249	NAD(P)H dehydrogenase (quinone) activity
FYA21_RS02155	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FYA21_RS02165	COG0277	FAD linked oxidase domain protein
FYA21_RS02170	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FYA21_RS02195	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FYA21_RS02200	COG5380	lipid catabolic process
FYA21_RS02220	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FYA21_RS02275	COG0194	GDP metabolic process
FYA21_RS02290	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA21_RS02310	COG3307	-O-antigen
FYA21_RS02335	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FYA21_RS02340	COG1704	LemA family
FYA21_RS02350	COG0493	'glutamate synthase
FYA21_RS02355	COG0067	glutamate synthase
FYA21_RS02355	COG0069	glutamate synthase activity
FYA21_RS02355	COG0070	glutamate synthase
FYA21_RS02405	COG2226	methyltransferase
FYA21_RS02420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FYA21_RS02425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FYA21_RS02470	COG0833	amino acid
FYA21_RS02535	COG0488	(ABC) transporter
FYA21_RS02545	COG4221	oxidoreductase activity
FYA21_RS02550	COG0659	secondary active sulfate transmembrane transporter activity
FYA21_RS02575	COG0427	acetyl-CoA hydrolase
FYA21_RS02605	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FYA21_RS02625	COG1132	(ABC) transporter
FYA21_RS02650	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FYA21_RS02680	COG1280	lysine exporter protein (LysE YggA)
FYA21_RS02705	COG0582	viral genome integration into host DNA
FYA21_RS02755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FYA21_RS02765	COG2249	NAD(P)H dehydrogenase (quinone) activity
FYA21_RS02775	COG1733	regulation of RNA biosynthetic process
FYA21_RS02815	COG0667	Aldo Keto reductase
FYA21_RS02835	COG0583	DNA-binding transcription factor activity
FYA21_RS02840	COG2814	Major facilitator Superfamily
FYA21_RS02870	COG1335	isochorismatase
FYA21_RS02880	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS02885	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYA21_RS02895	COG1113	amino acid transport
FYA21_RS02905	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FYA21_RS02920	COG2814	Major facilitator Superfamily
FYA21_RS02930	COG0351	phosphomethylpyrimidine kinase
FYA21_RS02930	COG0352	thiamine-phosphate diphosphorylase activity
FYA21_RS02930	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FYA21_RS02950	COG1309	transcriptional regulator
FYA21_RS02955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FYA21_RS02970	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYA21_RS02980	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYA21_RS02985	COG3162	membrane
FYA21_RS02990	COG0784	Response regulator, receiver
FYA21_RS02990	COG2198	Histidine kinase
FYA21_RS02990	COG2205	protein histidine kinase activity
FYA21_RS03015	COG1522	sequence-specific DNA binding
FYA21_RS03020	COG1335	isochorismatase
FYA21_RS03025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA21_RS03035	COG0668	transmembrane transport
FYA21_RS03040	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYA21_RS03045	COG1519	Transferase
FYA21_RS03050	COG1902	pentaerythritol trinitrate reductase activity
FYA21_RS03070	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FYA21_RS03095	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA21_RS03095	COG0426	domain, Protein
FYA21_RS03100	COG4774	siderophore transport
FYA21_RS03105	COG2119	membrane
FYA21_RS03115	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA21_RS03125	COG4942	peptidase
FYA21_RS03140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FYA21_RS03150	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FYA21_RS03170	COG0189	ligase activity
FYA21_RS03190	COG0708	Exodeoxyribonuclease III
FYA21_RS03195	COG1393	Belongs to the ArsC family
FYA21_RS03210	COG3706	GGDEF domain
FYA21_RS03245	COG2351	hydroxyisourate hydrolase activity
FYA21_RS03250	COG2233	PERMEase
FYA21_RS03260	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA21_RS03270	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FYA21_RS03280	COG3150	esterase
FYA21_RS03305	COG2918	glutathione biosynthetic process
FYA21_RS03320	COG2733	membrane
FYA21_RS03325	COG0436	Aminotransferase
FYA21_RS03330	COG0534	Mate efflux family protein
FYA21_RS03380	COG0753	catalase activity
FYA21_RS03430	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FYA21_RS03435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FYA21_RS03445	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FYA21_RS03460	COG1280	lysine exporter protein (LysE YggA)
FYA21_RS03465	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FYA21_RS03480	COG0010	Belongs to the arginase family
FYA21_RS03510	COG2188	Transcriptional regulator
FYA21_RS03520	COG0523	cobalamin synthesis protein
FYA21_RS03530	COG1113	amino acid transport
FYA21_RS03540	COG0625	glutathione transferase activity
FYA21_RS03560	COG1683	Conserved Protein
FYA21_RS03565	COG0534	Mate efflux family protein
FYA21_RS03570	COG0385	Bile acid
FYA21_RS03575	COG1335	isochorismatase
FYA21_RS03580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA21_RS03600	COG2116	formate transmembrane transporter activity
FYA21_RS03605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FYA21_RS03620	COG3188	usher protein
FYA21_RS03625	COG3121	Chaperone
FYA21_RS03635	COG2983	Belongs to the UPF0260 family
FYA21_RS03655	COG1194	a g-specific adenine glycosylase
FYA21_RS03670	COG2818	Glycosylase
FYA21_RS03675	COG1064	alcohol dehydrogenase
FYA21_RS03680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA21_RS03695	COG0583	DNA-binding transcription factor activity
FYA21_RS03700	COG0656	L-ascorbic acid biosynthetic process
FYA21_RS03705	COG2814	Major facilitator Superfamily
FYA21_RS03740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA21_RS03755	COG2233	PERMEase
FYA21_RS03760	COG0583	DNA-binding transcription factor activity
FYA21_RS03795	COG0733	neurotransmitter:sodium symporter activity
FYA21_RS03835	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FYA21_RS03840	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FYA21_RS03845	COG0596	Alpha beta hydrolase
FYA21_RS03870	COG0488	(ABC) transporter
FYA21_RS03875	COG0586	Pfam SNARE associated Golgi protein
FYA21_RS03885	COG0187	DNA topoisomerase II activity
FYA21_RS03895	COG0592	DNA-directed DNA polymerase activity
FYA21_RS03920	COG0706	membrane insertase activity
FYA21_RS03935	COG1230	cation diffusion facilitator family transporter
FYA21_RS03940	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA21_RS03955	COG0402	S-adenosylhomocysteine deaminase activity
FYA21_RS03965	COG0754	glutathionylspermidine amidase activity
FYA21_RS03975	COG0861	Integral membrane protein TerC family
FYA21_RS03980	COG0671	phosphoesterase, PA-phosphatase related
FYA21_RS03990	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FYA21_RS04010	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FYA21_RS04015	COG2951	lytic endotransglycosylase activity
FYA21_RS04065	COG0657	acetylesterase activity
FYA21_RS04070	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FYA21_RS04110	COG1047	Peptidyl-prolyl cis-trans
FYA21_RS04120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FYA21_RS04125	COG0196	riboflavin kinase activity
FYA21_RS04135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FYA21_RS04140	COG1309	transcriptional regulator
FYA21_RS04145	COG1116	anion transmembrane transporter activity
FYA21_RS04150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA21_RS04155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA21_RS04160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA21_RS04165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA21_RS04185	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS04190	COG0546	phosphoglycolate phosphatase activity
FYA21_RS04245	COG3023	N-Acetylmuramoyl-L-alanine amidase
FYA21_RS04250	COG0728	peptidoglycan biosynthetic process
FYA21_RS04285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA21_RS04290	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FYA21_RS04295	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FYA21_RS04320	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FYA21_RS04330	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FYA21_RS04340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FYA21_RS04355	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYA21_RS04365	COG2186	Transcriptional regulator
FYA21_RS04375	COG0277	FAD linked oxidase domain protein
FYA21_RS04380	COG1448	Aminotransferase
FYA21_RS04390	COG1802	Transcriptional regulator
FYA21_RS04405	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FYA21_RS04455	COG0564	pseudouridine synthase activity
FYA21_RS04495	COG0251	oxidation-reduction process
FYA21_RS04500	COG1113	amino acid transport
FYA21_RS04505	COG1113	amino acid transport
FYA21_RS04525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA21_RS04530	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS04535	COG1024	Enoyl-CoA hydratase
FYA21_RS04540	COG1024	Enoyl-CoA hydratase
FYA21_RS04545	COG0477	Major facilitator Superfamily
FYA21_RS04550	COG2197	response regulator
FYA21_RS04575	COG0271	Belongs to the BolA IbaG family
FYA21_RS04585	COG1192	Involved in chromosome partitioning
FYA21_RS04600	COG0586	Pfam SNARE associated Golgi protein
FYA21_RS04605	COG2259	Doxx family
FYA21_RS04610	COG4399	Belongs to the UPF0754 family
FYA21_RS04615	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA21_RS04615	COG0519	Catalyzes the synthesis of GMP from XMP
FYA21_RS04660	COG0281	malic enzyme
FYA21_RS04665	COG2837	iron assimilation
FYA21_RS04670	COG1280	lysine exporter protein (LysE YggA)
FYA21_RS04675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FYA21_RS04680	COG1121	(ABC) transporter
FYA21_RS04745	COG0386	Belongs to the glutathione peroxidase family
FYA21_RS04760	COG1309	transcriptional regulator
FYA21_RS04765	COG0697	spore germination
FYA21_RS04775	COG0758	DNA mediated transformation
FYA21_RS04810	COG1309	transcriptional regulator
FYA21_RS04845	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FYA21_RS04855	COG0655	NAD(P)H dehydrogenase (quinone) activity
FYA21_RS04890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FYA21_RS04900	COG0477	Major facilitator Superfamily
FYA21_RS04910	COG1253	flavin adenine dinucleotide binding
FYA21_RS04920	COG2860	membrane
FYA21_RS04925	COG0477	Major facilitator Superfamily
FYA21_RS04935	COG0318	PFAM AMP-dependent synthetase and ligase
FYA21_RS04950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FYA21_RS04965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA21_RS04975	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA21_RS04980	COG0606	chelatase, subunit chli
FYA21_RS04990	COG0347	Belongs to the P(II) protein family
FYA21_RS04995	COG0004	ammonium transporteR
FYA21_RS05005	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA21_RS05005	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FYA21_RS05045	COG0795	lipopolysaccharide-transporting ATPase activity
FYA21_RS05050	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FYA21_RS05055	COG0793	Belongs to the peptidase S41A family
FYA21_RS05070	COG2197	response regulator
FYA21_RS05080	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FYA21_RS05090	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FYA21_RS05095	COG4974	Belongs to the 'phage' integrase family
FYA21_RS05120	COG0772	Belongs to the SEDS family
FYA21_RS05125	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FYA21_RS05130	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FYA21_RS05135	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYA21_RS05160	COG0697	spore germination
FYA21_RS05165	COG1538	Outer membrane efflux protein
FYA21_RS05185	COG3275	phosphorelay sensor kinase activity
FYA21_RS05195	COG0181	hydroxymethylbilane synthase activity
FYA21_RS05240	COG1716	ATPase activity
FYA21_RS05245	COG0546	phosphoglycolate phosphatase activity
FYA21_RS05345	COG2056	Na+-H+ antiporter family
FYA21_RS05360	COG0326	Molecular chaperone. Has ATPase activity
FYA21_RS05375	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FYA21_RS05440	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FYA21_RS05445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA21_RS05445	COG2169	Transcriptional regulator
FYA21_RS05475	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FYA21_RS05485	COG0497	DNA recombination
FYA21_RS05500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA21_RS05510	COG0237	dephospho-CoA kinase activity
FYA21_RS05560	COG0195	Participates in both transcription termination and antitermination
FYA21_RS05575	COG1320	monovalent cation:proton antiporter activity
FYA21_RS05580	COG2212	antiporter activity
FYA21_RS05585	COG1863	multisubunit Na H antiporter MnhE subunit
FYA21_RS05590	COG0651	ATP synthesis coupled electron transport
FYA21_RS05595	COG1006	Multisubunit Na H antiporter MnhC subunit
FYA21_RS05600	COG2111	Na H antiporter
FYA21_RS05600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYA21_RS05615	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYA21_RS05635	COG2226	methyltransferase
FYA21_RS05655	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FYA21_RS05660	COG1074	ATP-dependent DNA helicase activity
FYA21_RS05665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FYA21_RS05670	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FYA21_RS05685	COG0598	Magnesium transport protein CorA
FYA21_RS05690	COG0789	Transcriptional regulator
FYA21_RS05695	COG0484	heat shock protein binding
FYA21_RS05710	COG0475	glutathione-regulated potassium exporter activity
FYA21_RS05710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FYA21_RS05715	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FYA21_RS05735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA21_RS05745	COG4535	Mg2 and Co2 transporter CorC
FYA21_RS05760	COG0644	oxidoreductase
FYA21_RS05760	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FYA21_RS05770	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FYA21_RS05785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYA21_RS05790	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FYA21_RS05800	COG0493	'glutamate synthase
FYA21_RS05800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA21_RS05825	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FYA21_RS05840	COG0534	Mate efflux family protein
FYA21_RS05850	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FYA21_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS05860	COG0583	DNA-binding transcription factor activity
FYA21_RS05875	COG0318	PFAM AMP-dependent synthetase and ligase
FYA21_RS05880	COG1530	ribonuclease E activity
FYA21_RS05895	COG0546	phosphoglycolate phosphatase activity
FYA21_RS05900	COG2378	regulation of single-species biofilm formation
FYA21_RS05905	COG0625	glutathione transferase activity
FYA21_RS05915	COG0583	DNA-binding transcription factor activity
FYA21_RS05980	COG0473	3-isopropylmalate dehydrogenase activity
FYA21_RS06035	COG1301	dicarboxylic acid transport
FYA21_RS06045	COG1560	Kdo2-lipid A biosynthetic process
FYA21_RS06050	COG1280	lysine exporter protein (LysE YggA)
FYA21_RS06055	COG0488	(ABC) transporter
FYA21_RS06060	COG2900	Belongs to the SlyX family
FYA21_RS06070	COG1733	regulation of RNA biosynthetic process
FYA21_RS06095	COG0210	DNA helicase
FYA21_RS06100	COG0724	RNA recognition motif
FYA21_RS06120	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FYA21_RS06120	COG4651	solute:proton antiporter activity
FYA21_RS06145	COG0788	formyltetrahydrofolate deformylase activity
FYA21_RS06245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA21_RS06245	COG2813	Specifically methylates the guanine in position
FYA21_RS06255	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA21_RS06265	COG4774	siderophore transport
FYA21_RS06275	COG0740	serine-type endopeptidase activity
FYA21_RS06295	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FYA21_RS06295	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FYA21_RS06300	COG0280	phosphate acetyltransferase
FYA21_RS06300	COG0857	belongs to the CobB CobQ family
FYA21_RS06305	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FYA21_RS06315	COG0800	Aldolase
FYA21_RS06325	COG3265	gluconokinase activity
FYA21_RS06330	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS06340	COG2267	carboxylic ester hydrolase activity
FYA21_RS06355	COG0793	Belongs to the peptidase S41A family
FYA21_RS06390	COG1426	Protein conserved in bacteria
FYA21_RS06430	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FYA21_RS06440	COG1162	GTPase activity
FYA21_RS06445	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FYA21_RS06460	COG1538	Outer membrane efflux protein
FYA21_RS06465	COG0577	efflux transmembrane transporter activity
FYA21_RS06465	COG1136	(ABC) transporter
FYA21_RS06470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA21_RS06495	COG0028	Belongs to the TPP enzyme family
FYA21_RS06500	COG0440	acetolactate synthase activity
FYA21_RS06535	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FYA21_RS06550	COG0084	hydrolase, TatD family'
FYA21_RS06565	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FYA21_RS06575	COG0583	DNA-binding transcription factor activity
FYA21_RS06585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYA21_RS06590	COG2814	Major facilitator Superfamily
FYA21_RS06600	COG0697	spore germination
FYA21_RS06635	COG3622	Belongs to the hyi family
FYA21_RS06640	COG2084	Dehydrogenase
FYA21_RS06645	COG1024	Enoyl-CoA hydratase
FYA21_RS06650	COG0784	Response regulator, receiver
FYA21_RS06650	COG2205	protein histidine kinase activity
FYA21_RS06650	COG5002	protein histidine kinase activity
FYA21_RS06670	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FYA21_RS06680	COG3956	TIGRFAM MazG family protein
FYA21_RS06685	COG1555	photosystem II stabilization
FYA21_RS06690	COG0617	tRNA 3'-terminal CCA addition
FYA21_RS06695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FYA21_RS06715	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYA21_RS06720	COG3028	Belongs to the UPF0307 family
FYA21_RS06725	COG0318	PFAM AMP-dependent synthetase and ligase
FYA21_RS06740	COG0625	glutathione transferase activity
FYA21_RS06745	COG1238	metal cluster binding
FYA21_RS06775	COG0072	phenylalanine-tRNA ligase activity
FYA21_RS06805	COG0248	Ppx GppA phosphatase
FYA21_RS06815	COG0037	tRNA processing
FYA21_RS06855	COG1764	response to oxidative stress
FYA21_RS06860	COG1846	Transcriptional regulator
FYA21_RS06870	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA21_RS06930	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FYA21_RS06935	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FYA21_RS06940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FYA21_RS06950	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FYA21_RS07000	COG1214	PFAM Peptidase M22, glycoprotease
FYA21_RS07025	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FYA21_RS07030	COG0561	phosphatase activity
FYA21_RS07040	COG2132	Multicopper oxidase
FYA21_RS07060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FYA21_RS07065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FYA21_RS07070	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FYA21_RS07100	COG1063	alcohol dehydrogenase
FYA21_RS07105	COG0583	DNA-binding transcription factor activity
FYA21_RS07110	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS07115	COG2814	Major facilitator Superfamily
FYA21_RS07120	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA21_RS07130	COG1053	succinate dehydrogenase
FYA21_RS07135	COG0583	DNA-binding transcription factor activity
FYA21_RS07155	COG0583	DNA-binding transcription factor activity
FYA21_RS07185	COG0583	DNA-binding transcription factor activity
FYA21_RS07200	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA21_RS07270	COG4993	Dehydrogenase
FYA21_RS07330	COG0084	hydrolase, TatD family'
FYA21_RS07340	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FYA21_RS07360	COG0745	RESPONSE REGULATOR receiver
FYA21_RS07400	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FYA21_RS07430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FYA21_RS07435	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FYA21_RS07455	COG0583	DNA-binding transcription factor activity
FYA21_RS07475	COG0668	transmembrane transport
FYA21_RS07485	COG2081	HI0933 family
FYA21_RS07490	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FYA21_RS07520	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA21_RS07520	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FYA21_RS07530	COG0489	protein tyrosine kinase activity
FYA21_RS07590	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FYA21_RS07600	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FYA21_RS07615	COG0730	response to heat
FYA21_RS07625	COG1196	nuclear chromosome segregation
FYA21_RS07645	COG2223	nitrite transmembrane transporter activity
FYA21_RS07650	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FYA21_RS07655	COG1877	trehalose-phosphatase activity
FYA21_RS07660	COG2226	methyltransferase
FYA21_RS07660	COG0596	Alpha beta hydrolase
FYA21_RS07660	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA21_RS07675	COG4106	trans-aconitate 2-methyltransferase activity
FYA21_RS07690	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FYA21_RS07695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FYA21_RS07700	COG0009	L-threonylcarbamoyladenylate synthase
FYA21_RS07705	COG3101	peptidyl-lysine hydroxylation
FYA21_RS07710	COG1399	metal-binding, possibly nucleic acid-binding protein
FYA21_RS07735	COG1652	LysM domain
FYA21_RS07740	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FYA21_RS07740	COG0352	thiamine-phosphate diphosphorylase activity
FYA21_RS07740	COG0351	phosphomethylpyrimidine kinase
FYA21_RS07750	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FYA21_RS07780	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYA21_RS07810	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FYA21_RS07825	COG0358	DNA primase activity
FYA21_RS07835	COG0564	pseudouridine synthase activity
FYA21_RS07860	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA21_RS07880	COG0583	DNA-binding transcription factor activity
FYA21_RS07885	COG0473	3-isopropylmalate dehydrogenase activity
FYA21_RS07895	COG0657	acetylesterase activity
FYA21_RS07905	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS07925	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FYA21_RS07925	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FYA21_RS07940	COG1981	membrane
FYA21_RS07985	COG0456	acetyltransferase
FYA21_RS07995	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FYA21_RS08000	COG0492	ferredoxin-NADP+ reductase activity
FYA21_RS08005	COG1674	ftsk spoiiie
FYA21_RS08010	COG1280	lysine exporter protein (LysE YggA)
FYA21_RS08025	COG2894	cell division
FYA21_RS08040	COG0204	Acyl-transferase
FYA21_RS08045	COG2885	chlorophyll binding
FYA21_RS08050	COG0210	DNA helicase
FYA21_RS08060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FYA21_RS08075	COG0121	glutamine amidotransferase
FYA21_RS08100	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA21_RS08105	COG0735	belongs to the Fur family
FYA21_RS08130	COG0420	3'-5' exonuclease activity
FYA21_RS08150	COG1090	epimerase
FYA21_RS08165	COG2050	protein possibly involved in aromatic compounds catabolism
FYA21_RS08175	COG2814	Major facilitator Superfamily
FYA21_RS08180	COG0405	Gamma-glutamyltransferase
FYA21_RS08190	COG0582	viral genome integration into host DNA
FYA21_RS08290	COG0477	Major facilitator Superfamily
FYA21_RS08295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FYA21_RS08345	COG0531	amino acid
FYA21_RS08350	COG2040	homocysteine
FYA21_RS08375	COG1309	transcriptional regulator
FYA21_RS08380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYA21_RS08385	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FYA21_RS08395	COG1607	acyl-coa hydrolase
FYA21_RS08405	COG0523	cobalamin synthesis protein
FYA21_RS08415	COG4681	YaeQ
FYA21_RS08425	COG0726	polysaccharide deacetylase
FYA21_RS08425	COG1649	PFAM Uncharacterised BCR, COG1649
FYA21_RS08430	COG1215	transferase activity, transferring glycosyl groups
FYA21_RS08440	COG1024	Enoyl-CoA hydratase
FYA21_RS08455	COG1414	Transcriptional regulator
FYA21_RS08475	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS08490	COG2271	Major facilitator Superfamily
FYA21_RS08500	COG2267	carboxylic ester hydrolase activity
FYA21_RS08505	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS08520	COG0028	Belongs to the TPP enzyme family
FYA21_RS08530	COG0477	Major facilitator Superfamily
FYA21_RS08535	COG0242	peptide deformylase activity
FYA21_RS08540	COG2066	Belongs to the glutaminase family
FYA21_RS08545	COG2207	Transcriptional regulator
FYA21_RS08550	COG2223	nitrite transmembrane transporter activity
FYA21_RS08570	COG0583	DNA-binding transcription factor activity
FYA21_RS08575	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS08580	COG2271	Major facilitator Superfamily
FYA21_RS08585	COG3959	Transketolase, thiamine diphosphate binding domain
FYA21_RS08590	COG3958	Transketolase
FYA21_RS08600	COG0306	phosphate transporter
FYA21_RS08620	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FYA21_RS08665	COG4181	ATPase activity
FYA21_RS08670	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FYA21_RS08700	COG0583	DNA-binding transcription factor activity
FYA21_RS08710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYA21_RS08715	COG1773	rubredoxin
FYA21_RS08765	COG2851	Citrate transporter
FYA21_RS08775	COG1253	flavin adenine dinucleotide binding
FYA21_RS08820	COG0804	urea catabolic process
FYA21_RS08830	COG0830	nickel cation binding
FYA21_RS08845	COG0742	ribosomal rna small subunit methyltransferase
FYA21_RS08850	COG0768	penicillin binding
FYA21_RS08875	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FYA21_RS08880	COG2878	Part of a membrane complex involved in electron transport
FYA21_RS08885	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FYA21_RS08895	COG3384	dioxygenase
FYA21_RS08915	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FYA21_RS09330	COG0006	proline dipeptidase activity
FYA21_RS09335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA21_RS09340	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA21_RS09360	COG1279	arginine transmembrane transporter activity
FYA21_RS09365	COG0583	DNA-binding transcription factor activity
FYA21_RS09405	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYA21_RS09410	COG0741	lytic transglycosylase activity
FYA21_RS09410	COG0741	lytic transglycosylase activity
FYA21_RS09410	COG1388	LysM domain
FYA21_RS09410	COG1388	LysM domain
FYA21_RS09420	COG4174	ABC transporter (Permease)
FYA21_RS09425	COG4239	(ABC) transporter, permease
FYA21_RS09430	COG4172	Belongs to the ABC transporter superfamily
FYA21_RS09455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FYA21_RS09465	COG2203	Gaf domain
FYA21_RS09465	COG5001	Diguanylate cyclase
FYA21_RS09465	COG3706	GGDEF domain
FYA21_RS09465	COG4251	negative regulation of phosphorylation
FYA21_RS09480	COG1902	pentaerythritol trinitrate reductase activity
FYA21_RS09480	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYA21_RS09490	COG0583	DNA-binding transcription factor activity
FYA21_RS09495	COG2851	Citrate transporter
FYA21_RS09560	COG4993	Dehydrogenase
FYA21_RS09575	COG1959	2 iron, 2 sulfur cluster binding
FYA21_RS09625	COG1309	transcriptional regulator
FYA21_RS09655	COG1294	oxidase, subunit
FYA21_RS09660	COG1271	oxidase subunit
FYA21_RS09675	COG4774	siderophore transport
FYA21_RS09690	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
FYA21_RS09695	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FYA21_RS09705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FYA21_RS09710	COG1469	GTP cyclohydrolase I activity
FYA21_RS09715	COG0735	belongs to the Fur family
FYA21_RS09720	COG0215	cysteine-tRNA ligase activity
FYA21_RS09755	COG0251	oxidation-reduction process
FYA21_RS09765	COG0583	DNA-binding transcription factor activity
FYA21_RS09805	COG3209	COG3209 Rhs family protein
FYA21_RS09845	COG1113	amino acid transport
FYA21_RS09855	COG0531	amino acid
FYA21_RS09875	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS09895	COG1113	amino acid transport
FYA21_RS09935	COG0697	spore germination
FYA21_RS09940	COG2721	sulfolactate sulfo-lyase activity
FYA21_RS09945	COG2271	Major facilitator Superfamily
FYA21_RS09950	COG4948	Mandelate Racemase Muconate Lactonizing
FYA21_RS09960	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS09965	COG2186	Transcriptional regulator
FYA21_RS09990	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS10000	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS10005	COG1024	Enoyl-CoA hydratase
FYA21_RS10010	COG2814	Major facilitator Superfamily
FYA21_RS10025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA21_RS10070	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FYA21_RS10075	COG2072	flavoprotein involved in K transport
FYA21_RS10080	COG0300	oxidoreductase activity
FYA21_RS10090	COG1309	transcriptional regulator
FYA21_RS10095	COG1741	Belongs to the pirin family
FYA21_RS10110	COG2072	flavoprotein involved in K transport
FYA21_RS10120	COG2252	PERMEase
FYA21_RS10125	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FYA21_RS10130	COG3038	cytochrome b561
FYA21_RS10140	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FYA21_RS10150	COG0527	aspartate kinase activity
FYA21_RS10160	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FYA21_RS10175	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FYA21_RS10190	COG0667	Aldo Keto reductase
FYA21_RS10200	COG1765	OsmC-like protein
FYA21_RS10215	COG0542	response to heat
FYA21_RS10250	COG2885	chlorophyll binding
FYA21_RS10260	COG0625	glutathione transferase activity
FYA21_RS10425	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FYA21_RS10445	COG3634	alkyl hydroperoxide reductase activity
FYA21_RS10455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FYA21_RS10465	COG0450	alkyl hydroperoxide reductase
FYA21_RS10470	COG1643	Atp-dependent helicase
FYA21_RS10485	COG2814	Major facilitator Superfamily
FYA21_RS10490	COG3135	benzoate transporter
FYA21_RS10495	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS10500	COG0543	2 iron, 2 sulfur cluster binding
FYA21_RS10500	COG0633	Ferredoxin
FYA21_RS10505	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FYA21_RS10510	COG4638	Rieske (2fe-2S)
FYA21_RS10515	COG0583	DNA-binding transcription factor activity
FYA21_RS10570	COG1570	exodeoxyribonuclease VII activity
FYA21_RS10605	COG1280	lysine exporter protein (LysE YggA)
FYA21_RS10610	COG1278	Cold shock
FYA21_RS10650	COG2814	Major facilitator Superfamily
FYA21_RS10695	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FYA21_RS10695	COG0517	IMP dehydrogenase activity
FYA21_RS10700	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FYA21_RS10710	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FYA21_RS10715	COG1137	ATPase activity
FYA21_RS10720	COG1538	Outer membrane efflux protein
FYA21_RS10750	COG4122	O-methyltransferase activity
FYA21_RS10760	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FYA21_RS10865	COG0583	DNA-binding transcription factor activity
FYA21_RS10870	COG1902	pentaerythritol trinitrate reductase activity
FYA21_RS10875	COG0006	proline dipeptidase activity
FYA21_RS10880	COG0477	Major facilitator Superfamily
FYA21_RS10895	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS10900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYA21_RS10905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FYA21_RS10905	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FYA21_RS10960	COG3123	guanosine phosphorylase activity
FYA21_RS10965	COG1522	sequence-specific DNA binding
FYA21_RS10970	COG5006	permease, DMT superfamily
FYA21_RS10980	COG1560	Kdo2-lipid A biosynthetic process
FYA21_RS11005	COG2814	Major facilitator Superfamily
FYA21_RS11025	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA21_RS11085	COG0583	DNA-binding transcription factor activity
FYA21_RS11090	COG1914	H( )-stimulated, divalent metal cation uptake system
FYA21_RS11110	COG4770	biotin carboxylase activity
FYA21_RS11115	COG0038	chloride channel
FYA21_RS11130	COG1309	transcriptional regulator
FYA21_RS11140	COG1063	alcohol dehydrogenase
FYA21_RS11155	COG0439	Biotin carboxylase
FYA21_RS11160	COG2249	NAD(P)H dehydrogenase (quinone) activity
FYA21_RS11165	COG1733	regulation of RNA biosynthetic process
FYA21_RS11175	COG0864	Transcriptional regulator
FYA21_RS11185	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA21_RS11190	COG1116	anion transmembrane transporter activity
FYA21_RS11310	COG0590	tRNA wobble adenosine to inosine editing
FYA21_RS11315	COG2807	transmembrane transport
FYA21_RS11330	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FYA21_RS11340	COG0789	Transcriptional regulator
FYA21_RS11355	COG1760	l-serine dehydratase
FYA21_RS11360	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS11360	COG2030	dehydratase
FYA21_RS11365	COG3396	Phenylacetate-CoA oxygenase
FYA21_RS11370	COG3460	Phenylacetate-CoA oxygenase
FYA21_RS11375	COG3396	Phenylacetate-CoA oxygenase
FYA21_RS11380	COG2151	metal-sulfur cluster biosynthetic enzyme
FYA21_RS11385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA21_RS11390	COG1024	Enoyl-CoA hydratase
FYA21_RS11395	COG1024	Enoyl-CoA hydratase
FYA21_RS11400	COG1250	3-hydroxyacyl-CoA dehydrogenase
FYA21_RS11410	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FYA21_RS11415	COG3327	negative regulation of DNA-templated transcription, initiation
FYA21_RS11425	COG2050	protein possibly involved in aromatic compounds catabolism
FYA21_RS11460	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FYA21_RS11465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FYA21_RS11470	COG2271	Major facilitator Superfamily
FYA21_RS11475	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYA21_RS11490	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FYA21_RS11495	COG0531	amino acid
FYA21_RS11500	COG0753	catalase activity
FYA21_RS11505	COG3038	cytochrome b561
FYA21_RS11510	COG0583	DNA-binding transcription factor activity
FYA21_RS11520	COG1414	Transcriptional regulator
FYA21_RS11525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FYA21_RS11540	COG1840	ABC-type Fe3 transport system, periplasmic component
FYA21_RS11545	COG3842	ATPase activity
FYA21_RS11560	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FYA21_RS11565	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FYA21_RS11585	COG0583	DNA-binding transcription factor activity
FYA21_RS11595	COG4770	biotin carboxylase activity
FYA21_RS11600	COG1024	Enoyl-CoA hydratase
FYA21_RS11605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FYA21_RS11610	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS11615	COG1309	transcriptional regulator
FYA21_RS11620	COG0318	PFAM AMP-dependent synthetase and ligase
FYA21_RS11640	COG0583	DNA-binding transcription factor activity
FYA21_RS11690	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS11710	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FYA21_RS11730	COG0784	Response regulator, receiver
FYA21_RS11730	COG2205	protein histidine kinase activity
FYA21_RS11770	COG0765	amino acid transport
FYA21_RS11775	COG0765	amino acid transport
FYA21_RS11780	COG1126	abc transporter atp-binding protein
FYA21_RS11785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA21_RS11790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FYA21_RS11805	COG1280	lysine exporter protein (LysE YggA)
FYA21_RS11810	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FYA21_RS11815	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYA21_RS11820	COG1045	serine acetyltransferase
FYA21_RS11835	COG0583	DNA-binding transcription factor activity
FYA21_RS11840	COG0625	glutathione transferase activity
FYA21_RS11845	COG0625	glutathione transferase activity
FYA21_RS11850	COG0583	DNA-binding transcription factor activity
FYA21_RS11860	COG1346	cytolysis
FYA21_RS11880	COG2814	Major facilitator Superfamily
FYA21_RS11890	COG0583	DNA-binding transcription factor activity
FYA21_RS11900	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FYA21_RS11905	COG3052	prosthetic group binding
FYA21_RS11925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FYA21_RS11945	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA21_RS11955	COG1294	oxidase, subunit
FYA21_RS11960	COG1271	oxidase subunit
FYA21_RS11985	COG0477	Major facilitator Superfamily
FYA21_RS11995	COG4521	taurine ABC transporter
FYA21_RS12000	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FYA21_RS12005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA21_RS12010	COG2175	clavaminate synthase activity
FYA21_RS12020	COG1953	Uracil, thiamine, allantoin
FYA21_RS12030	COG0583	DNA-binding transcription factor activity
FYA21_RS12040	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FYA21_RS12055	COG0640	Transcriptional regulator
FYA21_RS12060	COG0798	PFAM Bile acid sodium symporter
FYA21_RS12065	COG0583	DNA-binding transcription factor activity
FYA21_RS12080	COG3634	alkyl hydroperoxide reductase activity
FYA21_RS12120	COG0436	Aminotransferase
FYA21_RS12130	COG0386	Belongs to the glutathione peroxidase family
FYA21_RS12170	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FYA21_RS12195	COG0012	GTP binding
FYA21_RS12200	COG2011	ABC-type metal ion transport system permease component
FYA21_RS12205	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYA21_RS12215	COG1464	Belongs to the NlpA lipoprotein family
FYA21_RS12245	COG0765	amino acid transport
FYA21_RS12250	COG0765	amino acid transport
FYA21_RS12255	COG1126	abc transporter atp-binding protein
FYA21_RS12265	COG1522	sequence-specific DNA binding
FYA21_RS12280	COG1309	transcriptional regulator
FYA21_RS12300	COG0583	DNA-binding transcription factor activity
FYA21_RS12310	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FYA21_RS12320	COG0697	spore germination
FYA21_RS12350	COG3121	Chaperone
FYA21_RS12355	COG3539	Fimbrial protein
FYA21_RS12380	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FYA21_RS12380	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FYA21_RS12425	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FYA21_RS12435	COG2353	YceI-like domain
FYA21_RS12445	COG3698	Phosphodiester glycosidase
FYA21_RS12460	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FYA21_RS12465	COG0506	proline dehydrogenase activity
FYA21_RS12465	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA21_RS12465	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FYA21_RS12475	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FYA21_RS12480	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FYA21_RS12500	COG1132	(ABC) transporter
FYA21_RS12505	COG3122	Protein conserved in bacteria
FYA21_RS12510	COG3619	membrane
FYA21_RS12520	COG0640	Transcriptional regulator
FYA21_RS12530	COG2850	peptidyl-arginine hydroxylation
FYA21_RS12535	COG0424	maF-like protein
FYA21_RS12555	COG0191	fructose-bisphosphate aldolase activity
FYA21_RS12560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA21_RS12575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FYA21_RS12585	COG1192	Involved in chromosome partitioning
FYA21_RS12590	COG1475	DNA binding
FYA21_RS12595	COG0811	peptide transport
FYA21_RS12605	COG1132	(ABC) transporter
FYA21_RS12610	COG1663	tetraacyldisaccharide 4'-kinase activity
FYA21_RS12630	COG0084	hydrolase, TatD family'
FYA21_RS12695	COG0776	regulation of translation
FYA21_RS12725	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FYA21_RS12730	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FYA21_RS12775	COG0339	signal peptide processing
FYA21_RS12785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FYA21_RS12820	COG0702	epimerase
FYA21_RS12825	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FYA21_RS12845	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FYA21_RS12875	COG0316	Belongs to the HesB IscA family
FYA21_RS12880	COG0822	iron-sulfur transferase activity
FYA21_RS12905	COG0776	regulation of translation
FYA21_RS12910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FYA21_RS12915	COG2207	Transcriptional regulator
FYA21_RS12920	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA21_RS12925	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS12930	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS12945	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FYA21_RS12965	COG4264	IucA IucC family
FYA21_RS12970	COG4264	IucA IucC family
FYA21_RS12980	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FYA21_RS13030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FYA21_RS13035	COG0406	alpha-ribazole phosphatase activity
FYA21_RS13050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FYA21_RS13055	COG0730	response to heat
FYA21_RS13075	COG4773	Receptor
FYA21_RS13080	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA21_RS13095	COG1131	(ABC) transporter
FYA21_RS13100	COG0842	Transport permease protein
FYA21_RS13105	COG0842	Transport permease protein
FYA21_RS13160	COG2226	methyltransferase
FYA21_RS13185	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FYA21_RS13220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA21_RS13230	COG0133	tryptophan synthase activity
FYA21_RS13245	COG3706	GGDEF domain
FYA21_RS13260	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYA21_RS13265	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FYA21_RS13270	COG0022	dehydrogenase e1 component
FYA21_RS13275	COG0508	dehydrogenase complex catalyzes the overall conversion of
FYA21_RS13280	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA21_RS13290	COG1063	alcohol dehydrogenase
FYA21_RS13295	COG3781	membrane
FYA21_RS13305	COG3453	Protein conserved in bacteria
FYA21_RS13305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYA21_RS13315	COG0730	response to heat
FYA21_RS13330	COG3708	Transcriptional regulator
FYA21_RS13330	COG2207	Transcriptional regulator
FYA21_RS13335	COG1733	regulation of RNA biosynthetic process
FYA21_RS13340	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FYA21_RS13350	COG2188	Transcriptional regulator
FYA21_RS13365	COG4521	taurine ABC transporter
FYA21_RS13370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FYA21_RS13390	COG0477	Major facilitator Superfamily
FYA21_RS13400	COG1027	Aspartate ammonia-lyase
FYA21_RS13415	COG0583	DNA-binding transcription factor activity
FYA21_RS13420	COG0583	DNA-binding transcription factor activity
FYA21_RS13425	COG0183	Belongs to the thiolase family
FYA21_RS13430	COG2031	fatty acid transporter
FYA21_RS13445	COG0583	DNA-binding transcription factor activity
FYA21_RS13455	COG2610	gluconate transmembrane transporter activity
FYA21_RS13460	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS13465	COG2207	Transcriptional regulator
FYA21_RS13480	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS13490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA21_RS13505	COG0543	2 iron, 2 sulfur cluster binding
FYA21_RS13505	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA21_RS13510	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FYA21_RS13515	COG4638	Rieske (2fe-2S)
FYA21_RS13525	COG0725	ABC transporter, periplasmic molybdate-binding protein
FYA21_RS13530	COG4149	molybdate abc transporter
FYA21_RS13535	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FYA21_RS13540	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS13545	COG3433	isochorismatase activity
FYA21_RS13545	COG1535	isochorismatase
FYA21_RS13610	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FYA21_RS13625	COG0753	catalase activity
FYA21_RS13640	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FYA21_RS13670	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FYA21_RS13675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA21_RS13680	COG0745	RESPONSE REGULATOR receiver
FYA21_RS13685	COG2205	protein histidine kinase activity
FYA21_RS13695	COG2207	Transcriptional regulator
FYA21_RS13710	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS13725	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FYA21_RS13780	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FYA21_RS13830	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FYA21_RS13850	COG1120	ATPase activity
FYA21_RS13855	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA21_RS13870	COG1064	alcohol dehydrogenase
FYA21_RS13875	COG2207	Transcriptional regulator
FYA21_RS13880	COG2084	Dehydrogenase
FYA21_RS13890	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FYA21_RS13895	COG0583	DNA-binding transcription factor activity
FYA21_RS13905	COG0129	dihydroxy-acid dehydratase activity
FYA21_RS13910	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS13930	COG1566	PFAM secretion protein HlyD family protein
FYA21_RS13945	COG0583	DNA-binding transcription factor activity
FYA21_RS13960	COG2188	Transcriptional regulator
FYA21_RS14005	COG1309	transcriptional regulator
FYA21_RS14020	COG0318	PFAM AMP-dependent synthetase and ligase
FYA21_RS14030	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS14040	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS14045	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS14050	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS14055	COG0583	DNA-binding transcription factor activity
FYA21_RS14060	COG1309	transcriptional regulator
FYA21_RS14090	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FYA21_RS14100	COG1902	pentaerythritol trinitrate reductase activity
FYA21_RS14100	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYA21_RS14105	COG1846	Transcriptional regulator
FYA21_RS14130	COG0753	catalase activity
FYA21_RS14145	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS14160	COG3162	membrane
FYA21_RS14170	COG3829	transcription factor binding
FYA21_RS14175	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS14180	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS14195	COG3231	kanamycin kinase activity
FYA21_RS14200	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS14220	COG2186	Transcriptional regulator
FYA21_RS14230	COG0583	DNA-binding transcription factor activity
FYA21_RS14235	COG4948	Mandelate Racemase Muconate Lactonizing
FYA21_RS14240	COG4829	muconolactone delta-isomerase
FYA21_RS14250	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FYA21_RS14255	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYA21_RS14260	COG0183	Belongs to the thiolase family
FYA21_RS14265	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FYA21_RS14270	COG1012	belongs to the aldehyde dehydrogenase family
FYA21_RS14280	COG3733	amine oxidase
FYA21_RS14290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA21_RS14300	COG1028	Short-chain dehydrogenase reductase Sdr
FYA21_RS14310	COG4638	Rieske (2fe-2S)
FYA21_RS14330	COG0154	amidase activity
FYA21_RS14340	COG2814	Major facilitator Superfamily
FYA21_RS14365	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS14370	COG0583	DNA-binding transcription factor activity
FYA21_RS14375	COG1414	Transcriptional regulator
FYA21_RS14390	COG2391	methyltransferase activity
FYA21_RS14400	COG4993	Dehydrogenase
FYA21_RS14405	COG3659	wide pore channel activity
FYA21_RS14410	COG3420	alginic acid biosynthetic process
FYA21_RS14415	COG0710	3-dehydroquinate dehydratase activity
FYA21_RS14420	COG3485	protocatechuate 3,4-dioxygenase
FYA21_RS14425	COG3485	protocatechuate 3,4-dioxygenase
FYA21_RS14430	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FYA21_RS14435	COG2271	Major facilitator Superfamily
FYA21_RS14440	COG0596	Alpha beta hydrolase
FYA21_RS14445	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FYA21_RS14450	COG0183	Belongs to the thiolase family
FYA21_RS14455	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FYA21_RS14460	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FYA21_RS14470	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FYA21_RS14475	COG2323	membrane
FYA21_RS14520	COG0446	pyridine nucleotide-disulphide oxidoreductase
FYA21_RS14520	COG1902	pentaerythritol trinitrate reductase activity
FYA21_RS14545	COG0542	response to heat
FYA21_RS14550	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FYA21_RS14580	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FYA21_RS14585	COG0569	domain protein
FYA21_RS14590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FYA21_RS14605	COG4774	siderophore transport
FYA21_RS14610	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FYA21_RS14620	COG1585	Membrane protein implicated in regulation of membrane protease activity
FYA21_RS14635	COG1294	oxidase, subunit
FYA21_RS14640	COG4890	Cyd operon protein YbgT
FYA21_RS14655	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FYA21_RS14665	COG0552	protein localization to endoplasmic reticulum
FYA21_RS14690	COG0517	IMP dehydrogenase activity
FYA21_RS14690	COG0516	GMP reductase activity
FYA21_RS14695	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FYA21_RS14700	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FYA21_RS14710	COG0583	DNA-binding transcription factor activity
FYA21_RS14715	COG0024	Methionine aminopeptidase
FYA21_RS14745	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FYA21_RS14745	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FYA21_RS14750	COG1105	Belongs to the carbohydrate kinase PfkB family
FYA21_RS14755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FYA21_RS14755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FYA21_RS14755	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FYA21_RS14775	COG3300	MHYT domain
FYA21_RS14775	COG5001	Diguanylate cyclase
FYA21_RS14790	COG2135	peptidase activity
FYA21_RS14795	COG0659	secondary active sulfate transmembrane transporter activity
FYA21_RS14810	COG1113	amino acid transport
FYA21_RS14820	COG1522	sequence-specific DNA binding
FYA21_RS14845	COG1011	Hydrolase
FYA21_RS14850	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FYA21_RS14860	COG2137	regulation of response to DNA damage stimulus
FYA21_RS14875	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA21_RS14895	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FYA21_RS14910	COG0575	Belongs to the CDS family
FYA21_RS14915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FYA21_RS14940	COG3852	Histidine kinase
FYA21_RS14945	COG2204	response regulator
FYA21_RS15005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FYA21_RS15010	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FYA21_RS15030	COG0697	spore germination
FYA21_RS15035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA21_RS15045	COG0303	'Molybdopterin
FYA21_RS15050	COG0521	Mo-molybdopterin cofactor biosynthetic process
FYA21_RS15050	COG0315	cyclic pyranopterin monophosphate synthase activity
FYA21_RS15065	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FYA21_RS15070	COG0243	molybdopterin cofactor binding
FYA21_RS15080	COG0243	molybdopterin cofactor binding
FYA21_RS15085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYA21_RS15090	COG2146	nitrite reductase [NAD(P)H] activity
FYA21_RS15090	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FYA21_RS15100	COG0745	RESPONSE REGULATOR receiver
FYA21_RS15105	COG1116	anion transmembrane transporter activity
FYA21_RS15105	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FYA21_RS15125	COG0511	ligase activity, forming carbon-carbon bonds
FYA21_RS15140	COG2814	Major facilitator Superfamily
FYA21_RS15410	COG3620	sequence-specific DNA binding
FYA21_RS15500	COG0069	glutamate synthase activity
FYA21_RS15520	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FYA21_RS15530	COG1454	alcohol dehydrogenase
FYA21_RS15535	COG0824	Thioesterase
FYA21_RS15545	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FYA21_RS15560	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FYA21_RS15565	COG2030	dehydratase
FYA21_RS15575	COG0183	Belongs to the thiolase family
FYA21_RS15585	COG0583	DNA-binding transcription factor activity
FYA21_RS15590	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FYA21_RS15600	COG1522	sequence-specific DNA binding
FYA21_RS15605	COG3135	benzoate transporter
FYA21_RS15630	COG0589	response to stress
FYA21_RS15635	COG0488	(ABC) transporter
FYA21_RS15655	COG4773	Receptor
FYA21_RS15685	COG0668	transmembrane transport
FYA21_RS15695	COG1309	transcriptional regulator
FYA21_RS15725	COG1605	Chorismate mutase
FYA21_RS15765	COG0308	aminopeptidase N
FYA21_RS15785	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FYA21_RS15795	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FYA21_RS15800	COG1454	alcohol dehydrogenase
FYA21_RS15820	COG0531	amino acid
FYA21_RS15825	COG4303	Ethanolamine ammonia lyase large subunit
FYA21_RS15830	COG4302	ethanolamine ammonia-lyase activity
FYA21_RS15835	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FYA21_RS15835	COG0519	Catalyzes the synthesis of GMP from XMP
FYA21_RS15850	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FYA21_RS15865	COG0697	spore germination
FYA21_RS15870	COG1923	regulation of RNA biosynthetic process
FYA21_RS15880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FYA21_RS15885	COG0802	atpase or kinase
FYA21_RS15920	COG0583	DNA-binding transcription factor activity
FYA21_RS15935	COG2814	Major facilitator Superfamily
FYA21_RS15940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FYA21_RS15970	COG0729	surface antigen
FYA21_RS15990	COG0174	glutamine synthetase
FYA21_RS15995	COG0745	RESPONSE REGULATOR receiver
FYA21_RS16000	COG2205	protein histidine kinase activity
FYA21_RS16010	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FYA21_RS16015	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FYA21_RS16040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FYA21_RS16045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FYA21_RS16050	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS16080	COG0583	DNA-binding transcription factor activity
FYA21_RS16100	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FYA21_RS16110	COG3658	cytochrome
FYA21_RS16115	COG1215	transferase activity, transferring glycosyl groups
FYA21_RS16120	COG1649	PFAM Uncharacterised BCR, COG1649
FYA21_RS16120	COG0726	polysaccharide deacetylase
FYA21_RS16145	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FYA21_RS16150	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FYA21_RS16160	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FYA21_RS16185	COG0305	Participates in initiation and elongation during chromosome replication
FYA21_RS16190	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FYA21_RS16200	COG1305	Transglutaminase-like
FYA21_RS16210	COG2308	Evidence 4 Homologs of previously reported genes of
FYA21_RS16240	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FYA21_RS16245	COG0138	bifunctional purine biosynthesis protein purh
FYA21_RS16250	COG0151	Belongs to the GarS family
FYA21_RS16255	COG1464	Belongs to the NlpA lipoprotein family
FYA21_RS16260	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FYA21_RS16265	COG2011	ABC-type metal ion transport system permease component
FYA21_RS16270	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYA21_RS16280	COG1301	dicarboxylic acid transport
FYA21_RS16310	COG1794	racemase activity, acting on amino acids and derivatives
FYA21_RS16320	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FYA21_RS16320	COG3008	intermembrane lipid transfer
FYA21_RS16325	COG2995	paraquat-inducible protein a
FYA21_RS16350	COG0477	Major facilitator Superfamily
FYA21_RS16360	COG2186	Transcriptional regulator
FYA21_RS16370	COG0786	glutamate:sodium symporter activity
FYA21_RS16375	COG3243	poly(R)-hydroxyalkanoic acid synthase
FYA21_RS16400	COG3111	PFAM Bacterial OB fold (BOF) protein
FYA21_RS16470	COG0515	serine threonine protein kinase
FYA21_RS16470	COG2815	serine threonine protein kinase
FYA21_RS16500	COG1610	YqeY-like protein
FYA21_RS16530	COG1286	toxin biosynthetic process
FYA21_RS16560	COG0778	Nitroreductase
FYA21_RS16570	COG0513	Belongs to the DEAD box helicase family
FYA21_RS16590	COG2363	Small membrane protein
FYA21_RS16620	COG4650	regulator
FYA21_RS16625	COG1234	tRNA 3'-trailer cleavage
FYA21_RS16630	COG1690	Belongs to the RtcB family
FYA21_RS16650	COG2195	Cleaves the N-terminal amino acid of tripeptides
FYA21_RS16660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FYA21_RS16675	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS16680	COG1301	dicarboxylic acid transport
FYA21_RS16690	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FYA21_RS16695	COG3139	Protein of unknown function (DUF1315)
FYA21_RS16700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FYA21_RS16705	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FYA21_RS16715	COG0494	nUDIX hydrolase
FYA21_RS16725	COG0642	Histidine kinase
FYA21_RS16740	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FYA21_RS16750	COG1720	tRNA m6t6A37 methyltransferase activity
FYA21_RS16765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FYA21_RS16770	COG0826	peptidase U32
FYA21_RS16775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FYA21_RS16785	COG4598	ABC transporter
FYA21_RS16790	COG4160	amino acid transport
FYA21_RS16795	COG4215	(ABC) transporter
FYA21_RS16810	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA21_RS16855	COG1131	(ABC) transporter
FYA21_RS16860	COG0842	Transport permease protein
FYA21_RS16875	COG0772	Belongs to the SEDS family
FYA21_RS16880	COG2951	lytic endotransglycosylase activity
FYA21_RS16905	COG2207	Transcriptional regulator
FYA21_RS16920	COG0052	Belongs to the universal ribosomal protein uS2 family
FYA21_RS16925	COG0024	Methionine aminopeptidase
FYA21_RS16935	COG2223	nitrite transmembrane transporter activity
FYA21_RS16945	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FYA21_RS16950	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FYA21_RS16955	COG1960	acyl-CoA dehydrogenase activity
FYA21_RS16970	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FYA21_RS16975	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FYA21_RS16980	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FYA21_RS17000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA21_RS17005	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FYA21_RS17010	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FYA21_RS17045	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FYA21_RS17055	COG0174	glutamine synthetase
FYA21_RS17070	COG0512	Glutamine amidotransferase of anthranilate synthase
FYA21_RS17075	COG0308	aminopeptidase N
FYA21_RS17105	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FYA21_RS17115	COG0302	gtp cyclohydrolase
FYA21_RS17135	COG3739	integral membrane protein
FYA21_RS17150	COG1169	isochorismate synthase
FYA21_RS17160	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FYA21_RS17165	COG1132	(ABC) transporter
FYA21_RS17170	COG1132	(ABC) transporter
FYA21_RS17185	COG1535	isochorismatase
FYA21_RS17185	COG3433	isochorismatase activity
FYA21_RS17190	COG1021	2,3-dihydroxybenzoate-AMP ligase
FYA21_RS17195	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA21_RS17205	COG4774	siderophore transport
FYA21_RS17210	COG4607	ABC-type enterochelin transport system periplasmic component
FYA21_RS17215	COG4604	ABC transporter, ATP-binding protein
FYA21_RS17220	COG4605	iron ion homeostasis
FYA21_RS17225	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FYA21_RS17230	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA21_RS17245	COG2964	Protein conserved in bacteria
FYA21_RS17255	COG1741	Belongs to the pirin family
FYA21_RS17280	COG2879	small protein
FYA21_RS17285	COG1966	Carbon starvation protein
FYA21_RS17305	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FYA21_RS17330	COG1067	ATP-dependent peptidase activity
FYA21_RS17335	COG0583	DNA-binding transcription factor activity
FYA21_RS17360	COG1686	Belongs to the peptidase S11 family
FYA21_RS17365	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FYA21_RS17400	COG0616	signal peptide processing
FYA21_RS17405	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FYA21_RS17415	COG0573	inorganic phosphate transmembrane transporter activity
FYA21_RS17420	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FYA21_RS17425	COG1113	amino acid transport
FYA21_RS17430	COG3961	Belongs to the TPP enzyme family
FYA21_RS17435	COG1522	sequence-specific DNA binding
FYA21_RS17445	COG0076	glutamate decarboxylase activity
FYA21_RS17450	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FYA21_RS17460	COG1309	transcriptional regulator
FYA21_RS17475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FYA21_RS17510	COG0352	thiamine-phosphate diphosphorylase activity
FYA21_RS17535	COG0612	Peptidase, M16
FYA21_RS17545	COG1823	symporter activity
FYA21_RS17550	COG0583	DNA-binding transcription factor activity
FYA21_RS17555	COG0477	Major facilitator Superfamily
FYA21_RS17580	COG1187	pseudouridine synthase activity
FYA21_RS17595	COG1686	Belongs to the peptidase S11 family
FYA21_RS17600	COG1252	NADH dehydrogenase
FYA21_RS17610	COG0415	Belongs to the DNA photolyase family
FYA21_RS17625	COG1215	transferase activity, transferring glycosyl groups
FYA21_RS17655	COG2070	2-Nitropropane dioxygenase
FYA21_RS17710	COG0556	nucleotide-excision repair
FYA21_RS17730	COG0436	Aminotransferase
FYA21_RS17740	COG0443	Heat shock 70 kDa protein
FYA21_RS17770	COG4221	oxidoreductase activity
FYA21_RS17780	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FYA21_RS17785	COG1381	Involved in DNA repair and RecF pathway recombination
FYA21_RS17795	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FYA21_RS17810	COG0681	Belongs to the peptidase S26 family
FYA21_RS17820	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FYA21_RS17830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FYA21_RS17850	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FYA21_RS17855	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FYA21_RS17860	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FYA21_RS17870	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FYA21_RS17875	COG4208	sulfate ABC transporter
FYA21_RS17880	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FYA21_RS17885	COG0583	DNA-binding transcription factor activity
FYA21_RS17890	COG4625	pathogenesis
FYA21_RS17905	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FYA21_RS17920	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FYA21_RS17930	COG1056	cytidyltransferase-related domain
FYA21_RS17930	COG1051	belongs to the nudix hydrolase family
FYA21_RS17935	COG1024	Enoyl-CoA hydratase
FYA21_RS17945	COG2814	Major facilitator Superfamily
FYA21_RS17955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FYA21_RS17955	COG0047	phosphoribosylformylglycinamidine synthase activity
FYA21_RS17975	COG1473	amidohydrolase
FYA21_RS17980	COG0824	Thioesterase
FYA21_RS18000	COG0823	Involved in the tonB-independent uptake of proteins
FYA21_RS18020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FYA21_RS18055	COG0628	permease
FYA21_RS18065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FYA21_RS18070	COG0596	Alpha beta hydrolase
FYA21_RS18075	COG0616	signal peptide processing
FYA21_RS18075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FYA21_RS18085	COG0658	competence protein
FYA21_RS18085	COG2333	competence protein COMEC
FYA21_RS18090	COG1136	(ABC) transporter
FYA21_RS18095	COG4591	ABC-type transport system involved in lipoprotein release permease component
FYA21_RS18125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FYA21_RS18145	COG0463	Glycosyl transferase, family 2
FYA21_RS18175	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FYA21_RS18180	COG1280	lysine exporter protein (LysE YggA)
FYA21_RS18185	COG2267	carboxylic ester hydrolase activity
FYA21_RS18195	COG0019	diaminopimelate decarboxylase activity
FYA21_RS18205	COG1113	amino acid transport
FYA21_RS18220	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FYA21_RS18230	COG3339	Conserved Protein
FYA21_RS18235	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FYA21_RS18240	COG0243	molybdopterin cofactor binding
FYA21_RS18245	COG1929	Belongs to the glycerate kinase type-1 family
FYA21_RS18260	COG0778	Nitroreductase
FYA21_RS18285	COG3811	Belongs to the UPF0386 family
FYA21_RS18295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FYA21_RS18310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FYA21_RS18335	COG0741	lytic transglycosylase activity
FYA21_RS18355	COG0584	glycerophosphoryl diester phosphodiesterase
FYA21_RS18360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FYA21_RS18385	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FYA21_RS18390	COG1597	lipid kinase activity
FYA21_RS18405	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FYA21_RS18410	COG0477	Major facilitator Superfamily
FYA21_RS18460	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FYA21_RS18465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FYA21_RS18490	COG0505	Belongs to the CarA family
FYA21_RS18510	COG0589	response to stress
FYA21_RS18525	COG2843	Capsule synthesis protein