locus-tag	class	description
IUJ44_RS00015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
IUJ44_RS00025	COG0302	gtp cyclohydrolase
IUJ44_RS00045	COG3739	integral membrane protein
IUJ44_RS00060	COG1169	isochorismate synthase
IUJ44_RS00070	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
IUJ44_RS00075	COG1132	(ABC) transporter
IUJ44_RS00080	COG1132	(ABC) transporter
IUJ44_RS00090	COG1535	isochorismatase
IUJ44_RS00090	COG3433	isochorismatase activity
IUJ44_RS00095	COG1021	2,3-dihydroxybenzoate-AMP ligase
IUJ44_RS00100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ44_RS00110	COG4774	siderophore transport
IUJ44_RS00115	COG4607	ABC-type enterochelin transport system periplasmic component
IUJ44_RS00120	COG4604	ABC transporter, ATP-binding protein
IUJ44_RS00125	COG4605	iron ion homeostasis
IUJ44_RS00130	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ44_RS00135	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ44_RS00150	COG2964	Protein conserved in bacteria
IUJ44_RS00160	COG1741	Belongs to the pirin family
IUJ44_RS00195	COG2879	small protein
IUJ44_RS00200	COG1966	Carbon starvation protein
IUJ44_RS00220	COG4943	cyclic-guanylate-specific phosphodiesterase activity
IUJ44_RS00245	COG1067	ATP-dependent peptidase activity
IUJ44_RS00250	COG0583	DNA-binding transcription factor activity
IUJ44_RS00275	COG1686	Belongs to the peptidase S11 family
IUJ44_RS00280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IUJ44_RS00315	COG0616	signal peptide processing
IUJ44_RS00320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IUJ44_RS00330	COG0573	inorganic phosphate transmembrane transporter activity
IUJ44_RS00335	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IUJ44_RS00340	COG1113	amino acid transport
IUJ44_RS00345	COG3961	Belongs to the TPP enzyme family
IUJ44_RS00350	COG1522	sequence-specific DNA binding
IUJ44_RS00360	COG0076	glutamate decarboxylase activity
IUJ44_RS00365	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ44_RS00380	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ44_RS00390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ44_RS00425	COG0352	thiamine-phosphate diphosphorylase activity
IUJ44_RS00450	COG0612	Peptidase, M16
IUJ44_RS00460	COG1823	symporter activity
IUJ44_RS00465	COG0583	DNA-binding transcription factor activity
IUJ44_RS00470	COG0477	Major facilitator Superfamily
IUJ44_RS00495	COG1187	pseudouridine synthase activity
IUJ44_RS00510	COG1686	Belongs to the peptidase S11 family
IUJ44_RS00515	COG1252	NADH dehydrogenase
IUJ44_RS00525	COG0415	Belongs to the DNA photolyase family
IUJ44_RS00540	COG1215	transferase activity, transferring glycosyl groups
IUJ44_RS00570	COG2070	2-Nitropropane dioxygenase
IUJ44_RS00625	COG0556	nucleotide-excision repair
IUJ44_RS00645	COG0436	Aminotransferase
IUJ44_RS00655	COG0443	Heat shock 70 kDa protein
IUJ44_RS00685	COG4221	oxidoreductase activity
IUJ44_RS00695	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IUJ44_RS00700	COG1381	Involved in DNA repair and RecF pathway recombination
IUJ44_RS00710	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IUJ44_RS00725	COG0681	Belongs to the peptidase S26 family
IUJ44_RS00740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ44_RS00760	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IUJ44_RS00765	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IUJ44_RS00770	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
IUJ44_RS00780	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
IUJ44_RS00785	COG4208	sulfate ABC transporter
IUJ44_RS00790	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IUJ44_RS00795	COG0583	DNA-binding transcription factor activity
IUJ44_RS00800	COG4625	pathogenesis
IUJ44_RS00815	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
IUJ44_RS00830	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IUJ44_RS00840	COG1056	cytidyltransferase-related domain
IUJ44_RS00840	COG1051	belongs to the nudix hydrolase family
IUJ44_RS00845	COG1024	Enoyl-CoA hydratase
IUJ44_RS00855	COG2814	Major facilitator Superfamily
IUJ44_RS00860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IUJ44_RS00860	COG0047	phosphoribosylformylglycinamidine synthase activity
IUJ44_RS00880	COG1473	amidohydrolase
IUJ44_RS00885	COG0824	Thioesterase
IUJ44_RS00905	COG0823	Involved in the tonB-independent uptake of proteins
IUJ44_RS00925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ44_RS00960	COG0628	permease
IUJ44_RS00970	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IUJ44_RS00975	COG0596	Alpha beta hydrolase
IUJ44_RS00980	COG0616	signal peptide processing
IUJ44_RS00980	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
IUJ44_RS00990	COG0658	competence protein
IUJ44_RS00990	COG2333	competence protein COMEC
IUJ44_RS00995	COG1136	(ABC) transporter
IUJ44_RS01000	COG4591	ABC-type transport system involved in lipoprotein release permease component
IUJ44_RS01035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ44_RS01055	COG0463	Glycosyl transferase, family 2
IUJ44_RS01085	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IUJ44_RS01090	COG1280	lysine exporter protein (LysE YggA)
IUJ44_RS01095	COG2267	carboxylic ester hydrolase activity
IUJ44_RS01110	COG0019	diaminopimelate decarboxylase activity
IUJ44_RS01120	COG1113	amino acid transport
IUJ44_RS01135	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
IUJ44_RS01145	COG3339	Conserved Protein
IUJ44_RS01150	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IUJ44_RS01155	COG0243	molybdopterin cofactor binding
IUJ44_RS01160	COG1929	Belongs to the glycerate kinase type-1 family
IUJ44_RS01175	COG0778	Nitroreductase
IUJ44_RS01200	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ44_RS01215	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IUJ44_RS01235	COG0741	lytic transglycosylase activity
IUJ44_RS01255	COG0584	glycerophosphoryl diester phosphodiesterase
IUJ44_RS01260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ44_RS01285	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ44_RS01290	COG1597	lipid kinase activity
IUJ44_RS01305	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IUJ44_RS01310	COG0477	Major facilitator Superfamily
IUJ44_RS01360	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IUJ44_RS01365	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IUJ44_RS01390	COG0505	Belongs to the CarA family
IUJ44_RS01410	COG0589	response to stress
IUJ44_RS01425	COG2843	Capsule synthesis protein
IUJ44_RS01445	COG2321	neutral zinc metallopeptidase
IUJ44_RS01450	COG2354	Protein conserved in bacteria
IUJ44_RS01470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ44_RS01495	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IUJ44_RS01500	COG1053	succinate dehydrogenase
IUJ44_RS01505	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
IUJ44_RS01510	COG2009	succinate dehydrogenase
IUJ44_RS01545	COG2921	Belongs to the UPF0250 family
IUJ44_RS01550	COG0321	lipoyl(octanoyl) transferase activity
IUJ44_RS01565	COG0531	amino acid
IUJ44_RS01580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IUJ44_RS01585	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
IUJ44_RS01585	COG1648	precorrin-2 dehydrogenase activity
IUJ44_RS01600	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IUJ44_RS01630	COG0671	phosphoesterase, PA-phosphatase related
IUJ44_RS01635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ44_RS01645	COG1538	Outer membrane efflux protein
IUJ44_RS01650	COG0393	Putative heavy-metal-binding
IUJ44_RS01655	COG0393	Putative heavy-metal-binding
IUJ44_RS01665	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS01675	COG0525	valine-tRNA ligase activity
IUJ44_RS01695	COG0583	DNA-binding transcription factor activity
IUJ44_RS01700	COG0004	ammonium transporteR
IUJ44_RS01715	COG0642	Histidine kinase
IUJ44_RS01720	COG0745	RESPONSE REGULATOR receiver
IUJ44_RS01725	COG2194	sulfuric ester hydrolase activity
IUJ44_RS01745	COG1752	Esterase of the alpha-beta hydrolase superfamily
IUJ44_RS01760	COG2315	Protein conserved in bacteria
IUJ44_RS01765	COG0142	geranyltranstransferase activity
IUJ44_RS01770	COG2828	Protein conserved in bacteria
IUJ44_RS01775	COG1113	amino acid transport
IUJ44_RS01795	COG2207	Transcriptional regulator
IUJ44_RS01820	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ44_RS01830	COG0560	Phosphoserine phosphatase
IUJ44_RS01840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
IUJ44_RS01850	COG1530	ribonuclease E activity
IUJ44_RS01855	COG0424	maF-like protein
IUJ44_RS01860	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
IUJ44_RS01865	COG1792	Involved in formation and maintenance of cell shape
IUJ44_RS01870	COG1077	Cell shape determining protein MreB Mrl
IUJ44_RS01875	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IUJ44_RS01885	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IUJ44_RS01910	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
IUJ44_RS01915	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ44_RS01920	COG1752	Esterase of the alpha-beta hydrolase superfamily
IUJ44_RS01925	COG1115	amino acid carrier protein
IUJ44_RS01945	COG2814	Major facilitator Superfamily
IUJ44_RS01950	COG1289	transmembrane transporter activity
IUJ44_RS01960	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
IUJ44_RS02000	COG1376	ErfK ybiS ycfS ynhG family protein
IUJ44_RS02005	COG2832	Protein of unknown function (DUF454)
IUJ44_RS02015	COG5510	response to toxic substance
IUJ44_RS02035	COG0840	transmembrane signaling receptor activity
IUJ44_RS02075	COG3422	double-strand break repair
IUJ44_RS02080	COG2824	Alkylphosphonate utilization operon protein PhnA
IUJ44_RS02085	COG3189	MarR family transcriptional regulator
IUJ44_RS02095	COG0354	folic acid binding
IUJ44_RS02100	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ44_RS02110	COG0679	Auxin Efflux Carrier
IUJ44_RS02115	COG1902	pentaerythritol trinitrate reductase activity
IUJ44_RS02120	COG4772	TonB-dependent receptor
IUJ44_RS02125	COG2094	Belongs to the DNA glycosylase MPG family
IUJ44_RS02150	COG1217	gtp-binding protein TYPA
IUJ44_RS02155	COG2233	PERMEase
IUJ44_RS02165	COG0833	amino acid
IUJ44_RS02170	COG1690	Belongs to the RtcB family
IUJ44_RS02180	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
IUJ44_RS02180	COG2885	chlorophyll binding
IUJ44_RS02190	COG0183	Belongs to the thiolase family
IUJ44_RS02210	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ44_RS02230	COG2207	Transcriptional regulator
IUJ44_RS02235	COG0183	Belongs to the thiolase family
IUJ44_RS02265	COG1272	protein, Hemolysin III
IUJ44_RS02270	COG0477	Major facilitator Superfamily
IUJ44_RS02285	COG0450	alkyl hydroperoxide reductase
IUJ44_RS02305	COG0285	dihydrofolate synthase activity
IUJ44_RS02350	COG4206	TonB-dependent receptor
IUJ44_RS02355	COG2096	Adenosyltransferase
IUJ44_RS02375	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
IUJ44_RS02380	COG0745	RESPONSE REGULATOR receiver
IUJ44_RS02385	COG2205	protein histidine kinase activity
IUJ44_RS02395	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS02400	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS02405	COG0583	DNA-binding transcription factor activity
IUJ44_RS02410	COG0625	glutathione transferase activity
IUJ44_RS02475	COG0438	transferase activity, transferring glycosyl groups
IUJ44_RS02480	COG0463	Glycosyl transferase, family 2
IUJ44_RS02485	COG0726	polysaccharide deacetylase
IUJ44_RS02505	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IUJ44_RS02510	COG2205	protein histidine kinase activity
IUJ44_RS02545	COG1862	Preprotein translocase
IUJ44_RS02555	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IUJ44_RS02560	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IUJ44_RS02570	COG3781	membrane
IUJ44_RS02575	COG0613	PHP domain protein
IUJ44_RS02585	COG2350	Protein conserved in bacteria
IUJ44_RS02615	COG1607	acyl-coa hydrolase
IUJ44_RS02675	COG2199	diguanylate cyclase activity
IUJ44_RS02685	COG1408	metallophosphoesterase
IUJ44_RS02690	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ44_RS02700	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IUJ44_RS02720	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IUJ44_RS02725	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IUJ44_RS02740	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IUJ44_RS02750	COG2969	positive regulation of protein catabolic process
IUJ44_RS02770	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS02775	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IUJ44_RS02790	COG1309	transcriptional regulator
IUJ44_RS02795	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS02840	COG1183	phosphatidylcholine synthase activity
IUJ44_RS02845	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IUJ44_RS02875	COG0741	lytic transglycosylase activity
IUJ44_RS02875	COG0739	heme binding
IUJ44_RS02875	COG1196	nuclear chromosome segregation
IUJ44_RS02885	COG1702	phosphate starvation-inducible protein PhoH
IUJ44_RS02920	COG1295	ribonuclease BN
IUJ44_RS02925	COG0697	spore germination
IUJ44_RS02930	COG2169	Transcriptional regulator
IUJ44_RS02935	COG0179	Fumarylacetoacetate (FAA) hydrolase
IUJ44_RS02980	COG0557	exoribonuclease II activity
IUJ44_RS02985	COG0339	signal peptide processing
IUJ44_RS02990	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
IUJ44_RS03020	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IUJ44_RS03025	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS03180	COG0626	cystathionine gamma-synthase activity
IUJ44_RS03185	COG0433	COG0433 Predicted ATPase
IUJ44_RS03190	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ44_RS03190	COG1017	nitric oxide dioxygenase activity
IUJ44_RS03195	COG1959	2 iron, 2 sulfur cluster binding
IUJ44_RS03210	COG1301	dicarboxylic acid transport
IUJ44_RS03215	COG1946	Acyl-CoA thioesterase
IUJ44_RS03235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IUJ44_RS03240	COG1040	competence protein
IUJ44_RS03245	COG0494	nUDIX hydrolase
IUJ44_RS03255	COG0598	Magnesium transport protein CorA
IUJ44_RS03265	COG2854	intermembrane phospholipid transfer
IUJ44_RS03275	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IUJ44_RS03280	COG1127	ABC transporter
IUJ44_RS03290	COG0513	Belongs to the DEAD box helicase family
IUJ44_RS03310	COG0408	coproporphyrinogen oxidase activity
IUJ44_RS03325	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS03335	COG1983	PspC domain protein
IUJ44_RS03340	COG0517	IMP dehydrogenase activity
IUJ44_RS03380	COG0583	DNA-binding transcription factor activity
IUJ44_RS03420	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS03430	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IUJ44_RS03435	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IUJ44_RS03440	COG0833	amino acid
IUJ44_RS03470	COG1192	Involved in chromosome partitioning
IUJ44_RS03475	COG0628	permease
IUJ44_RS03485	COG1289	transmembrane transporter activity
IUJ44_RS03500	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ44_RS03505	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
IUJ44_RS03515	COG0277	FAD linked oxidase domain protein
IUJ44_RS03520	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
IUJ44_RS03545	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IUJ44_RS03550	COG5380	lipid catabolic process
IUJ44_RS03570	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IUJ44_RS03620	COG0194	GDP metabolic process
IUJ44_RS03635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ44_RS03655	COG3307	-O-antigen
IUJ44_RS03675	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
IUJ44_RS03680	COG1704	LemA family
IUJ44_RS03690	COG0493	'glutamate synthase
IUJ44_RS03695	COG0069	glutamate synthase activity
IUJ44_RS03695	COG0070	glutamate synthase
IUJ44_RS03695	COG0067	glutamate synthase
IUJ44_RS03745	COG2226	methyltransferase
IUJ44_RS03760	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IUJ44_RS03765	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IUJ44_RS03810	COG0833	amino acid
IUJ44_RS03875	COG0488	(ABC) transporter
IUJ44_RS03880	COG2873	o-acetylhomoserine
IUJ44_RS03885	COG4221	oxidoreductase activity
IUJ44_RS03890	COG0659	secondary active sulfate transmembrane transporter activity
IUJ44_RS03915	COG0427	acetyl-CoA hydrolase
IUJ44_RS03945	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IUJ44_RS03985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
IUJ44_RS04055	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ44_RS04060	COG1733	regulation of RNA biosynthetic process
IUJ44_RS04090	COG0667	Aldo Keto reductase
IUJ44_RS04110	COG0583	DNA-binding transcription factor activity
IUJ44_RS04115	COG2814	Major facilitator Superfamily
IUJ44_RS04145	COG1335	isochorismatase
IUJ44_RS04155	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS04160	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
IUJ44_RS04170	COG1113	amino acid transport
IUJ44_RS04180	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IUJ44_RS04230	COG2814	Major facilitator Superfamily
IUJ44_RS04240	COG0351	phosphomethylpyrimidine kinase
IUJ44_RS04240	COG0352	thiamine-phosphate diphosphorylase activity
IUJ44_RS04240	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IUJ44_RS04260	COG1309	transcriptional regulator
IUJ44_RS04265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IUJ44_RS04280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ44_RS04290	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ44_RS04295	COG3162	membrane
IUJ44_RS04300	COG2198	Histidine kinase
IUJ44_RS04300	COG2205	protein histidine kinase activity
IUJ44_RS04300	COG0784	Response regulator, receiver
IUJ44_RS04325	COG1522	sequence-specific DNA binding
IUJ44_RS04330	COG1335	isochorismatase
IUJ44_RS04335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ44_RS04345	COG0668	transmembrane transport
IUJ44_RS04350	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IUJ44_RS04355	COG1519	Transferase
IUJ44_RS04360	COG1902	pentaerythritol trinitrate reductase activity
IUJ44_RS04380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IUJ44_RS04405	COG0426	domain, Protein
IUJ44_RS04405	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ44_RS04410	COG4774	siderophore transport
IUJ44_RS04415	COG2119	membrane
IUJ44_RS04425	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ44_RS04435	COG4942	peptidase
IUJ44_RS04450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
IUJ44_RS04460	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IUJ44_RS04480	COG0189	ligase activity
IUJ44_RS04500	COG0708	Exodeoxyribonuclease III
IUJ44_RS04505	COG1393	Belongs to the ArsC family
IUJ44_RS04520	COG3706	GGDEF domain
IUJ44_RS04555	COG2351	hydroxyisourate hydrolase activity
IUJ44_RS04560	COG2233	PERMEase
IUJ44_RS04570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ44_RS04580	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
IUJ44_RS04585	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS04595	COG3150	esterase
IUJ44_RS04610	COG3179	chitinase
IUJ44_RS04625	COG2918	glutathione biosynthetic process
IUJ44_RS04640	COG2733	membrane
IUJ44_RS04645	COG0436	Aminotransferase
IUJ44_RS04650	COG0534	Mate efflux family protein
IUJ44_RS04700	COG0753	catalase activity
IUJ44_RS04745	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IUJ44_RS04750	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IUJ44_RS04760	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IUJ44_RS04765	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IUJ44_RS04770	COG0546	phosphoglycolate phosphatase activity
IUJ44_RS04780	COG0010	Belongs to the arginase family
IUJ44_RS04810	COG2188	Transcriptional regulator
IUJ44_RS04820	COG0523	cobalamin synthesis protein
IUJ44_RS04830	COG1113	amino acid transport
IUJ44_RS04840	COG0625	glutathione transferase activity
IUJ44_RS04860	COG1683	Conserved Protein
IUJ44_RS04870	COG0385	Bile acid
IUJ44_RS04875	COG1335	isochorismatase
IUJ44_RS04880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ44_RS04900	COG2116	formate transmembrane transporter activity
IUJ44_RS04905	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IUJ44_RS04910	COG2133	pyrroloquinoline quinone binding
IUJ44_RS04915	COG2983	Belongs to the UPF0260 family
IUJ44_RS04935	COG1194	a g-specific adenine glycosylase
IUJ44_RS04950	COG2818	Glycosylase
IUJ44_RS04955	COG1064	alcohol dehydrogenase
IUJ44_RS04960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ44_RS04975	COG0583	DNA-binding transcription factor activity
IUJ44_RS04980	COG0656	L-ascorbic acid biosynthetic process
IUJ44_RS04985	COG2814	Major facilitator Superfamily
IUJ44_RS05020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ44_RS05035	COG2233	PERMEase
IUJ44_RS05040	COG0583	DNA-binding transcription factor activity
IUJ44_RS05075	COG0733	neurotransmitter:sodium symporter activity
IUJ44_RS05085	COG0625	glutathione transferase activity
IUJ44_RS05120	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IUJ44_RS05125	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
IUJ44_RS05130	COG0596	Alpha beta hydrolase
IUJ44_RS05155	COG0488	(ABC) transporter
IUJ44_RS05160	COG0586	Pfam SNARE associated Golgi protein
IUJ44_RS05170	COG0187	DNA topoisomerase II activity
IUJ44_RS05180	COG0592	DNA-directed DNA polymerase activity
IUJ44_RS05205	COG0706	membrane insertase activity
IUJ44_RS05220	COG1230	cation diffusion facilitator family transporter
IUJ44_RS05225	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ44_RS05240	COG0402	S-adenosylhomocysteine deaminase activity
IUJ44_RS05250	COG0754	glutathionylspermidine amidase activity
IUJ44_RS05260	COG0861	Integral membrane protein TerC family
IUJ44_RS05265	COG0671	phosphoesterase, PA-phosphatase related
IUJ44_RS05275	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IUJ44_RS05290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IUJ44_RS05295	COG2951	lytic endotransglycosylase activity
IUJ44_RS05325	COG0583	DNA-binding transcription factor activity
IUJ44_RS05345	COG0657	acetylesterase activity
IUJ44_RS05350	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IUJ44_RS05390	COG1047	Peptidyl-prolyl cis-trans
IUJ44_RS05400	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IUJ44_RS05405	COG0196	riboflavin kinase activity
IUJ44_RS05415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IUJ44_RS05420	COG1309	transcriptional regulator
IUJ44_RS05425	COG1116	anion transmembrane transporter activity
IUJ44_RS05430	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ44_RS05435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ44_RS05440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ44_RS05445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ44_RS05465	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS05470	COG0546	phosphoglycolate phosphatase activity
IUJ44_RS05570	COG4691	Plasmid stability protein
IUJ44_RS05605	COG0798	PFAM Bile acid sodium symporter
IUJ44_RS05640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ44_RS05660	COG2184	nucleotidyltransferase activity
IUJ44_RS05765	COG3023	N-Acetylmuramoyl-L-alanine amidase
IUJ44_RS05770	COG0728	peptidoglycan biosynthetic process
IUJ44_RS05795	COG1596	polysaccharide export
IUJ44_RS05800	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IUJ44_RS05830	COG0438	transferase activity, transferring glycosyl groups
IUJ44_RS05855	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IUJ44_RS05860	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IUJ44_RS05875	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IUJ44_RS05880	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ44_RS05890	COG2186	Transcriptional regulator
IUJ44_RS05900	COG0277	FAD linked oxidase domain protein
IUJ44_RS05905	COG1448	Aminotransferase
IUJ44_RS05910	COG1802	Transcriptional regulator
IUJ44_RS05925	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IUJ44_RS06010	COG0564	pseudouridine synthase activity
IUJ44_RS06050	COG0251	oxidation-reduction process
IUJ44_RS06055	COG1113	amino acid transport
IUJ44_RS06060	COG1113	amino acid transport
IUJ44_RS06080	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ44_RS06085	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS06090	COG1024	Enoyl-CoA hydratase
IUJ44_RS06095	COG1024	Enoyl-CoA hydratase
IUJ44_RS06100	COG0477	Major facilitator Superfamily
IUJ44_RS06105	COG3916	Acyl-homoserine-lactone synthase
IUJ44_RS06115	COG2197	response regulator
IUJ44_RS06125	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS06130	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IUJ44_RS06130	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
IUJ44_RS06130	COG3321	synthase
IUJ44_RS06130	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IUJ44_RS06150	COG2267	carboxylic ester hydrolase activity
IUJ44_RS06170	COG0271	Belongs to the BolA IbaG family
IUJ44_RS06180	COG1192	Involved in chromosome partitioning
IUJ44_RS06195	COG0586	Pfam SNARE associated Golgi protein
IUJ44_RS06200	COG2259	Doxx family
IUJ44_RS06205	COG4399	Belongs to the UPF0754 family
IUJ44_RS06210	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ44_RS06210	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ44_RS06255	COG0281	malic enzyme
IUJ44_RS06260	COG2837	iron assimilation
IUJ44_RS06265	COG1280	lysine exporter protein (LysE YggA)
IUJ44_RS06270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IUJ44_RS06275	COG1121	(ABC) transporter
IUJ44_RS06340	COG0386	Belongs to the glutathione peroxidase family
IUJ44_RS06355	COG1309	transcriptional regulator
IUJ44_RS06360	COG0697	spore germination
IUJ44_RS06370	COG0758	DNA mediated transformation
IUJ44_RS06440	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IUJ44_RS06450	COG0655	NAD(P)H dehydrogenase (quinone) activity
IUJ44_RS06490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IUJ44_RS06500	COG2814	Major facilitator Superfamily
IUJ44_RS06510	COG1253	flavin adenine dinucleotide binding
IUJ44_RS06520	COG2860	membrane
IUJ44_RS06525	COG0477	Major facilitator Superfamily
IUJ44_RS06535	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ44_RS06550	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IUJ44_RS06565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ44_RS06580	COG0606	chelatase, subunit chli
IUJ44_RS06590	COG0347	Belongs to the P(II) protein family
IUJ44_RS06595	COG0004	ammonium transporteR
IUJ44_RS06605	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ44_RS06605	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IUJ44_RS06645	COG0795	lipopolysaccharide-transporting ATPase activity
IUJ44_RS06650	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IUJ44_RS06655	COG0793	Belongs to the peptidase S41A family
IUJ44_RS06670	COG2197	response regulator
IUJ44_RS06680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
IUJ44_RS06690	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IUJ44_RS06695	COG4974	Belongs to the 'phage' integrase family
IUJ44_RS06720	COG0772	Belongs to the SEDS family
IUJ44_RS06725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ44_RS06730	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
IUJ44_RS06735	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
IUJ44_RS06760	COG0697	spore germination
IUJ44_RS06765	COG1538	Outer membrane efflux protein
IUJ44_RS06785	COG3275	phosphorelay sensor kinase activity
IUJ44_RS06795	COG0181	hydroxymethylbilane synthase activity
IUJ44_RS06840	COG1716	ATPase activity
IUJ44_RS06845	COG0546	phosphoglycolate phosphatase activity
IUJ44_RS06945	COG2056	Na+-H+ antiporter family
IUJ44_RS06960	COG0326	Molecular chaperone. Has ATPase activity
IUJ44_RS06975	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IUJ44_RS07035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IUJ44_RS07040	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ44_RS07040	COG2169	Transcriptional regulator
IUJ44_RS07070	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IUJ44_RS07080	COG0497	DNA recombination
IUJ44_RS07095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IUJ44_RS07105	COG0237	dephospho-CoA kinase activity
IUJ44_RS07110	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
IUJ44_RS07155	COG0195	Participates in both transcription termination and antitermination
IUJ44_RS07170	COG1320	monovalent cation:proton antiporter activity
IUJ44_RS07175	COG2212	antiporter activity
IUJ44_RS07180	COG1863	multisubunit Na H antiporter MnhE subunit
IUJ44_RS07185	COG0651	ATP synthesis coupled electron transport
IUJ44_RS07190	COG1006	Multisubunit Na H antiporter MnhC subunit
IUJ44_RS07195	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IUJ44_RS07195	COG2111	Na H antiporter
IUJ44_RS07210	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IUJ44_RS07215	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ44_RS07230	COG2226	methyltransferase
IUJ44_RS07250	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
IUJ44_RS07255	COG1074	ATP-dependent DNA helicase activity
IUJ44_RS07260	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IUJ44_RS07265	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
IUJ44_RS07280	COG0598	Magnesium transport protein CorA
IUJ44_RS07285	COG0789	Transcriptional regulator
IUJ44_RS07290	COG0484	heat shock protein binding
IUJ44_RS07305	COG0475	glutathione-regulated potassium exporter activity
IUJ44_RS07305	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ44_RS07310	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IUJ44_RS07330	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ44_RS07340	COG4535	Mg2 and Co2 transporter CorC
IUJ44_RS07345	COG0425	Belongs to the sulfur carrier protein TusA family
IUJ44_RS07350	COG0644	oxidoreductase
IUJ44_RS07350	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
IUJ44_RS07360	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
IUJ44_RS07375	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ44_RS07380	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
IUJ44_RS07390	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ44_RS07390	COG0493	'glutamate synthase
IUJ44_RS07415	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IUJ44_RS07430	COG0534	Mate efflux family protein
IUJ44_RS07440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IUJ44_RS07445	COG4221	oxidoreductase activity
IUJ44_RS07450	COG0583	DNA-binding transcription factor activity
IUJ44_RS07465	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ44_RS07470	COG1530	ribonuclease E activity
IUJ44_RS07480	COG0546	phosphoglycolate phosphatase activity
IUJ44_RS07485	COG2378	regulation of single-species biofilm formation
IUJ44_RS07490	COG0625	glutathione transferase activity
IUJ44_RS07500	COG0583	DNA-binding transcription factor activity
IUJ44_RS07565	COG0473	3-isopropylmalate dehydrogenase activity
IUJ44_RS07620	COG1301	dicarboxylic acid transport
IUJ44_RS07630	COG1560	Kdo2-lipid A biosynthetic process
IUJ44_RS07635	COG1280	lysine exporter protein (LysE YggA)
IUJ44_RS07640	COG0488	(ABC) transporter
IUJ44_RS07645	COG2900	Belongs to the SlyX family
IUJ44_RS07655	COG1733	regulation of RNA biosynthetic process
IUJ44_RS07680	COG0210	DNA helicase
IUJ44_RS07685	COG0724	RNA recognition motif
IUJ44_RS07705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IUJ44_RS07705	COG4651	solute:proton antiporter activity
IUJ44_RS07730	COG0788	formyltetrahydrofolate deformylase activity
IUJ44_RS07880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ44_RS07880	COG2813	Specifically methylates the guanine in position
IUJ44_RS07890	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ44_RS07900	COG4774	siderophore transport
IUJ44_RS07910	COG0740	serine-type endopeptidase activity
IUJ44_RS07930	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
IUJ44_RS07930	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
IUJ44_RS07935	COG0280	phosphate acetyltransferase
IUJ44_RS07935	COG0857	belongs to the CobB CobQ family
IUJ44_RS07940	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IUJ44_RS07950	COG0800	Aldolase
IUJ44_RS07960	COG3265	gluconokinase activity
IUJ44_RS07965	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS07975	COG2267	carboxylic ester hydrolase activity
IUJ44_RS07990	COG0793	Belongs to the peptidase S41A family
IUJ44_RS08025	COG1426	Protein conserved in bacteria
IUJ44_RS08065	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IUJ44_RS08075	COG1162	GTPase activity
IUJ44_RS08080	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IUJ44_RS08095	COG1538	Outer membrane efflux protein
IUJ44_RS08100	COG0577	efflux transmembrane transporter activity
IUJ44_RS08100	COG1136	(ABC) transporter
IUJ44_RS08105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ44_RS08130	COG0028	Belongs to the TPP enzyme family
IUJ44_RS08135	COG0440	acetolactate synthase activity
IUJ44_RS08165	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IUJ44_RS08180	COG0084	hydrolase, TatD family'
IUJ44_RS08195	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IUJ44_RS08205	COG0583	DNA-binding transcription factor activity
IUJ44_RS08215	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IUJ44_RS08220	COG2814	Major facilitator Superfamily
IUJ44_RS08230	COG0697	spore germination
IUJ44_RS08260	COG3622	Belongs to the hyi family
IUJ44_RS08265	COG2084	Dehydrogenase
IUJ44_RS08270	COG1024	Enoyl-CoA hydratase
IUJ44_RS08275	COG5002	protein histidine kinase activity
IUJ44_RS08275	COG0784	Response regulator, receiver
IUJ44_RS08275	COG2205	protein histidine kinase activity
IUJ44_RS08295	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IUJ44_RS08305	COG3956	TIGRFAM MazG family protein
IUJ44_RS08310	COG1555	photosystem II stabilization
IUJ44_RS08315	COG0617	tRNA 3'-terminal CCA addition
IUJ44_RS08320	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IUJ44_RS08340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ44_RS08345	COG3028	Belongs to the UPF0307 family
IUJ44_RS08350	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ44_RS08365	COG0625	glutathione transferase activity
IUJ44_RS08370	COG1238	metal cluster binding
IUJ44_RS08415	COG0072	phenylalanine-tRNA ligase activity
IUJ44_RS08445	COG0248	Ppx GppA phosphatase
IUJ44_RS08455	COG0037	tRNA processing
IUJ44_RS08470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUJ44_RS08470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IUJ44_RS08495	COG1764	response to oxidative stress
IUJ44_RS08500	COG1846	Transcriptional regulator
IUJ44_RS08510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ44_RS08570	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IUJ44_RS08575	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IUJ44_RS08580	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IUJ44_RS08590	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
IUJ44_RS08640	COG1214	PFAM Peptidase M22, glycoprotease
IUJ44_RS08655	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
IUJ44_RS08665	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IUJ44_RS08670	COG0561	phosphatase activity
IUJ44_RS08680	COG2132	Multicopper oxidase
IUJ44_RS08700	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IUJ44_RS08705	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IUJ44_RS08710	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
IUJ44_RS08740	COG1063	alcohol dehydrogenase
IUJ44_RS08745	COG0583	DNA-binding transcription factor activity
IUJ44_RS08750	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS08755	COG2814	Major facilitator Superfamily
IUJ44_RS08760	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ44_RS08765	COG1309	transcriptional regulator
IUJ44_RS08780	COG1053	succinate dehydrogenase
IUJ44_RS08785	COG0583	DNA-binding transcription factor activity
IUJ44_RS08800	COG0583	DNA-binding transcription factor activity
IUJ44_RS08810	COG0583	DNA-binding transcription factor activity
IUJ44_RS08825	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ44_RS08880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IUJ44_RS08900	COG0745	RESPONSE REGULATOR receiver
IUJ44_RS08940	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
IUJ44_RS08970	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
IUJ44_RS08975	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IUJ44_RS08995	COG0583	DNA-binding transcription factor activity
IUJ44_RS09015	COG0668	transmembrane transport
IUJ44_RS09025	COG2081	HI0933 family
IUJ44_RS09030	COG2515	1-aminocyclopropane-1-carboxylate deaminase
IUJ44_RS09060	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ44_RS09060	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IUJ44_RS09070	COG0489	protein tyrosine kinase activity
IUJ44_RS09075	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IUJ44_RS09120	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IUJ44_RS09130	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IUJ44_RS09145	COG0730	response to heat
IUJ44_RS09155	COG1196	nuclear chromosome segregation
IUJ44_RS09175	COG2223	nitrite transmembrane transporter activity
IUJ44_RS09180	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
IUJ44_RS09185	COG1877	trehalose-phosphatase activity
IUJ44_RS09190	COG2226	methyltransferase
IUJ44_RS09190	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ44_RS09190	COG0596	Alpha beta hydrolase
IUJ44_RS09205	COG4106	trans-aconitate 2-methyltransferase activity
IUJ44_RS09220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IUJ44_RS09225	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IUJ44_RS09230	COG0009	L-threonylcarbamoyladenylate synthase
IUJ44_RS09235	COG3101	peptidyl-lysine hydroxylation
IUJ44_RS09240	COG1399	metal-binding, possibly nucleic acid-binding protein
IUJ44_RS09265	COG1652	LysM domain
IUJ44_RS09270	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IUJ44_RS09270	COG0352	thiamine-phosphate diphosphorylase activity
IUJ44_RS09270	COG0351	phosphomethylpyrimidine kinase
IUJ44_RS09280	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IUJ44_RS09310	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IUJ44_RS09340	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
IUJ44_RS09355	COG0358	DNA primase activity
IUJ44_RS09365	COG0564	pseudouridine synthase activity
IUJ44_RS09390	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ44_RS09410	COG0583	DNA-binding transcription factor activity
IUJ44_RS09415	COG0473	3-isopropylmalate dehydrogenase activity
IUJ44_RS09425	COG0657	acetylesterase activity
IUJ44_RS09435	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS09455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IUJ44_RS09455	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IUJ44_RS09470	COG1981	membrane
IUJ44_RS09515	COG0456	acetyltransferase
IUJ44_RS09525	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
IUJ44_RS09530	COG0492	ferredoxin-NADP+ reductase activity
IUJ44_RS09535	COG1674	ftsk spoiiie
IUJ44_RS09540	COG1280	lysine exporter protein (LysE YggA)
IUJ44_RS09555	COG2894	cell division
IUJ44_RS09570	COG0204	Acyl-transferase
IUJ44_RS09575	COG2885	chlorophyll binding
IUJ44_RS09580	COG0210	DNA helicase
IUJ44_RS09590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IUJ44_RS09605	COG0121	glutamine amidotransferase
IUJ44_RS09625	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IUJ44_RS09630	COG0735	belongs to the Fur family
IUJ44_RS09655	COG0420	3'-5' exonuclease activity
IUJ44_RS09675	COG1090	epimerase
IUJ44_RS09690	COG2050	protein possibly involved in aromatic compounds catabolism
IUJ44_RS09700	COG2814	Major facilitator Superfamily
IUJ44_RS09705	COG0405	Gamma-glutamyltransferase
IUJ44_RS09715	COG0582	viral genome integration into host DNA
IUJ44_RS09760	COG0629	single-stranded DNA binding
IUJ44_RS09890	COG0477	Major facilitator Superfamily
IUJ44_RS09895	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ44_RS09940	COG0531	amino acid
IUJ44_RS09945	COG2040	homocysteine
IUJ44_RS09970	COG1309	transcriptional regulator
IUJ44_RS09975	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ44_RS09980	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IUJ44_RS09990	COG1607	acyl-coa hydrolase
IUJ44_RS10000	COG0523	cobalamin synthesis protein
IUJ44_RS10010	COG4681	YaeQ
IUJ44_RS10020	COG1649	PFAM Uncharacterised BCR, COG1649
IUJ44_RS10020	COG0726	polysaccharide deacetylase
IUJ44_RS10025	COG1215	transferase activity, transferring glycosyl groups
IUJ44_RS10035	COG1024	Enoyl-CoA hydratase
IUJ44_RS10050	COG1414	Transcriptional regulator
IUJ44_RS10070	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS10085	COG2271	Major facilitator Superfamily
IUJ44_RS10095	COG2267	carboxylic ester hydrolase activity
IUJ44_RS10100	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS10115	COG0028	Belongs to the TPP enzyme family
IUJ44_RS10125	COG0477	Major facilitator Superfamily
IUJ44_RS10130	COG0242	peptide deformylase activity
IUJ44_RS10135	COG2066	Belongs to the glutaminase family
IUJ44_RS10140	COG2207	Transcriptional regulator
IUJ44_RS10145	COG2223	nitrite transmembrane transporter activity
IUJ44_RS10160	COG0583	DNA-binding transcription factor activity
IUJ44_RS10165	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS10170	COG2271	Major facilitator Superfamily
IUJ44_RS10175	COG3959	Transketolase, thiamine diphosphate binding domain
IUJ44_RS10180	COG3958	Transketolase
IUJ44_RS10190	COG0306	phosphate transporter
IUJ44_RS10210	COG1262	PFAM Formylglycine-generating sulfatase enzyme
IUJ44_RS10255	COG4181	ATPase activity
IUJ44_RS10260	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
IUJ44_RS10290	COG0583	DNA-binding transcription factor activity
IUJ44_RS10300	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ44_RS10305	COG1773	rubredoxin
IUJ44_RS10355	COG2851	Citrate transporter
IUJ44_RS10360	COG1253	flavin adenine dinucleotide binding
IUJ44_RS10400	COG0804	urea catabolic process
IUJ44_RS10410	COG0830	nickel cation binding
IUJ44_RS10425	COG0742	ribosomal rna small subunit methyltransferase
IUJ44_RS10430	COG0768	penicillin binding
IUJ44_RS10455	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IUJ44_RS10460	COG2878	Part of a membrane complex involved in electron transport
IUJ44_RS10465	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IUJ44_RS10475	COG3384	dioxygenase
IUJ44_RS10500	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IUJ44_RS10825	COG0739	heme binding
IUJ44_RS10870	COG2194	sulfuric ester hydrolase activity
IUJ44_RS10910	COG0006	proline dipeptidase activity
IUJ44_RS10915	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ44_RS10920	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ44_RS10940	COG1279	arginine transmembrane transporter activity
IUJ44_RS10945	COG0583	DNA-binding transcription factor activity
IUJ44_RS10985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUJ44_RS10990	COG0741	lytic transglycosylase activity
IUJ44_RS10990	COG1388	LysM domain
IUJ44_RS10990	COG0741	lytic transglycosylase activity
IUJ44_RS10990	COG1388	LysM domain
IUJ44_RS11000	COG4174	ABC transporter (Permease)
IUJ44_RS11005	COG4239	(ABC) transporter, permease
IUJ44_RS11010	COG4172	Belongs to the ABC transporter superfamily
IUJ44_RS11030	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUJ44_RS11040	COG5001	Diguanylate cyclase
IUJ44_RS11040	COG2203	Gaf domain
IUJ44_RS11040	COG3706	GGDEF domain
IUJ44_RS11040	COG4251	negative regulation of phosphorylation
IUJ44_RS11050	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ44_RS11050	COG1902	pentaerythritol trinitrate reductase activity
IUJ44_RS11060	COG0582	viral genome integration into host DNA
IUJ44_RS11135	COG0789	Transcriptional regulator
IUJ44_RS11195	COG2184	nucleotidyltransferase activity
IUJ44_RS11205	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IUJ44_RS11230	COG1309	transcriptional regulator
IUJ44_RS11245	COG4269	membrane
IUJ44_RS11285	COG1113	amino acid transport
IUJ44_RS11295	COG0531	amino acid
IUJ44_RS11315	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS11335	COG1113	amino acid transport
IUJ44_RS11370	COG0697	spore germination
IUJ44_RS11375	COG2721	sulfolactate sulfo-lyase activity
IUJ44_RS11380	COG2271	Major facilitator Superfamily
IUJ44_RS11385	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ44_RS11395	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS11400	COG2186	Transcriptional regulator
IUJ44_RS11425	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS11435	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS11440	COG1024	Enoyl-CoA hydratase
IUJ44_RS11445	COG2814	Major facilitator Superfamily
IUJ44_RS11460	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ44_RS11505	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
IUJ44_RS11510	COG2072	flavoprotein involved in K transport
IUJ44_RS11515	COG0300	oxidoreductase activity
IUJ44_RS11525	COG1309	transcriptional regulator
IUJ44_RS11530	COG1741	Belongs to the pirin family
IUJ44_RS11545	COG2072	flavoprotein involved in K transport
IUJ44_RS11555	COG2252	PERMEase
IUJ44_RS11560	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IUJ44_RS11565	COG3038	cytochrome b561
IUJ44_RS11575	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IUJ44_RS11585	COG0527	aspartate kinase activity
IUJ44_RS11640	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IUJ44_RS11645	COG4197	protein conserved in bacteria, prophage-related
IUJ44_RS11725	COG5410	chromosome segregation
IUJ44_RS11730	COG3567	Phage-associated protein, HI1409 family
IUJ44_RS11750	COG3566	protein conserved in bacteria
IUJ44_RS11875	COG0582	viral genome integration into host DNA
IUJ44_RS11885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IUJ44_RS11895	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IUJ44_RS11910	COG0667	Aldo Keto reductase
IUJ44_RS11925	COG1765	OsmC-like protein
IUJ44_RS11940	COG0542	response to heat
IUJ44_RS11975	COG2885	chlorophyll binding
IUJ44_RS11985	COG0625	glutathione transferase activity
IUJ44_RS12005	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IUJ44_RS12025	COG3634	alkyl hydroperoxide reductase activity
IUJ44_RS12035	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IUJ44_RS12045	COG0450	alkyl hydroperoxide reductase
IUJ44_RS12050	COG1643	Atp-dependent helicase
IUJ44_RS12065	COG2814	Major facilitator Superfamily
IUJ44_RS12070	COG3135	benzoate transporter
IUJ44_RS12075	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS12080	COG0543	2 iron, 2 sulfur cluster binding
IUJ44_RS12080	COG0633	Ferredoxin
IUJ44_RS12085	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IUJ44_RS12090	COG4638	Rieske (2fe-2S)
IUJ44_RS12100	COG0583	DNA-binding transcription factor activity
IUJ44_RS12150	COG1570	exodeoxyribonuclease VII activity
IUJ44_RS12180	COG1280	lysine exporter protein (LysE YggA)
IUJ44_RS12185	COG1278	Cold shock
IUJ44_RS12220	COG2814	Major facilitator Superfamily
IUJ44_RS12300	COG0210	DNA helicase
IUJ44_RS12310	COG5377	YqaJ viral recombinase family
IUJ44_RS12515	COG0517	IMP dehydrogenase activity
IUJ44_RS12515	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
IUJ44_RS12520	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
IUJ44_RS12530	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
IUJ44_RS12535	COG1137	ATPase activity
IUJ44_RS12615	COG4122	O-methyltransferase activity
IUJ44_RS12625	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IUJ44_RS12640	COG1522	sequence-specific DNA binding
IUJ44_RS12655	COG1560	Kdo2-lipid A biosynthetic process
IUJ44_RS12670	COG2814	Major facilitator Superfamily
IUJ44_RS12690	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ44_RS12725	COG0583	DNA-binding transcription factor activity
IUJ44_RS12730	COG1914	H( )-stimulated, divalent metal cation uptake system
IUJ44_RS12750	COG4770	biotin carboxylase activity
IUJ44_RS12755	COG0038	chloride channel
IUJ44_RS12760	COG2831	hemolysin activation secretion protein
IUJ44_RS12765	COG3210	domain, Protein
IUJ44_RS12780	COG1309	transcriptional regulator
IUJ44_RS12790	COG1063	alcohol dehydrogenase
IUJ44_RS12805	COG0439	Biotin carboxylase
IUJ44_RS12810	COG2249	NAD(P)H dehydrogenase (quinone) activity
IUJ44_RS12815	COG1733	regulation of RNA biosynthetic process
IUJ44_RS12830	COG0864	Transcriptional regulator
IUJ44_RS12840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ44_RS12845	COG1116	anion transmembrane transporter activity
IUJ44_RS12965	COG0590	tRNA wobble adenosine to inosine editing
IUJ44_RS12970	COG2807	transmembrane transport
IUJ44_RS12985	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IUJ44_RS13005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IUJ44_RS13050	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS13055	COG0531	amino acid
IUJ44_RS13060	COG1760	l-serine dehydratase
IUJ44_RS13065	COG2030	dehydratase
IUJ44_RS13065	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS13070	COG3396	Phenylacetate-CoA oxygenase
IUJ44_RS13075	COG3460	Phenylacetate-CoA oxygenase
IUJ44_RS13080	COG3396	Phenylacetate-CoA oxygenase
IUJ44_RS13085	COG2151	metal-sulfur cluster biosynthetic enzyme
IUJ44_RS13090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ44_RS13095	COG1024	Enoyl-CoA hydratase
IUJ44_RS13100	COG1024	Enoyl-CoA hydratase
IUJ44_RS13105	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ44_RS13110	COG0183	Belongs to the thiolase family
IUJ44_RS13115	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
IUJ44_RS13120	COG3327	negative regulation of DNA-templated transcription, initiation
IUJ44_RS13130	COG2050	protein possibly involved in aromatic compounds catabolism
IUJ44_RS13170	COG2207	Transcriptional regulator
IUJ44_RS13185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
IUJ44_RS13190	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IUJ44_RS13195	COG2271	Major facilitator Superfamily
IUJ44_RS13200	COG0753	catalase activity
IUJ44_RS13205	COG3038	cytochrome b561
IUJ44_RS13225	COG2267	carboxylic ester hydrolase activity
IUJ44_RS13230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ44_RS13235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ44_RS13240	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS13250	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IUJ44_RS13260	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS13265	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ44_RS13270	COG0583	DNA-binding transcription factor activity
IUJ44_RS13280	COG1414	Transcriptional regulator
IUJ44_RS13285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IUJ44_RS13295	COG1840	ABC-type Fe3 transport system, periplasmic component
IUJ44_RS13300	COG3842	ATPase activity
IUJ44_RS13315	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
IUJ44_RS13320	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ44_RS13325	COG2814	Major facilitator Superfamily
IUJ44_RS13330	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS13345	COG1024	Enoyl-CoA hydratase
IUJ44_RS13355	COG2814	Major facilitator Superfamily
IUJ44_RS13365	COG0183	Belongs to the thiolase family
IUJ44_RS13370	COG1250	3-hydroxyacyl-CoA dehydrogenase
IUJ44_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS13380	COG1024	Enoyl-CoA hydratase
IUJ44_RS13385	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS13390	COG2814	Major facilitator Superfamily
IUJ44_RS13395	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IUJ44_RS13400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ44_RS13410	COG2814	Major facilitator Superfamily
IUJ44_RS13420	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS13435	COG0583	DNA-binding transcription factor activity
IUJ44_RS13445	COG4770	biotin carboxylase activity
IUJ44_RS13450	COG1024	Enoyl-CoA hydratase
IUJ44_RS13455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
IUJ44_RS13460	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS13465	COG1309	transcriptional regulator
IUJ44_RS13470	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ44_RS13490	COG0583	DNA-binding transcription factor activity
IUJ44_RS13540	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS13565	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IUJ44_RS13585	COG0784	Response regulator, receiver
IUJ44_RS13585	COG2205	protein histidine kinase activity
IUJ44_RS13605	COG0765	amino acid transport
IUJ44_RS13610	COG0765	amino acid transport
IUJ44_RS13615	COG1126	abc transporter atp-binding protein
IUJ44_RS13620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ44_RS13625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IUJ44_RS13640	COG1280	lysine exporter protein (LysE YggA)
IUJ44_RS13645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
IUJ44_RS13650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ44_RS13655	COG1045	serine acetyltransferase
IUJ44_RS13670	COG0583	DNA-binding transcription factor activity
IUJ44_RS13675	COG0625	glutathione transferase activity
IUJ44_RS13680	COG0625	glutathione transferase activity
IUJ44_RS13685	COG0583	DNA-binding transcription factor activity
IUJ44_RS13695	COG1346	cytolysis
IUJ44_RS13715	COG2814	Major facilitator Superfamily
IUJ44_RS13725	COG0583	DNA-binding transcription factor activity
IUJ44_RS13740	COG3052	prosthetic group binding
IUJ44_RS13780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ44_RS13790	COG1294	oxidase, subunit
IUJ44_RS13795	COG1271	oxidase subunit
IUJ44_RS13815	COG0477	Major facilitator Superfamily
IUJ44_RS13825	COG4521	taurine ABC transporter
IUJ44_RS13830	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
IUJ44_RS13835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ44_RS13840	COG2175	clavaminate synthase activity
IUJ44_RS13850	COG1953	Uracil, thiamine, allantoin
IUJ44_RS13860	COG0583	DNA-binding transcription factor activity
IUJ44_RS13870	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IUJ44_RS13885	COG0640	Transcriptional regulator
IUJ44_RS13890	COG0798	PFAM Bile acid sodium symporter
IUJ44_RS13895	COG0583	DNA-binding transcription factor activity
IUJ44_RS13910	COG3634	alkyl hydroperoxide reductase activity
IUJ44_RS13950	COG0436	Aminotransferase
IUJ44_RS13960	COG0386	Belongs to the glutathione peroxidase family
IUJ44_RS14000	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IUJ44_RS14025	COG0012	GTP binding
IUJ44_RS14030	COG2011	ABC-type metal ion transport system permease component
IUJ44_RS14035	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IUJ44_RS14045	COG1464	Belongs to the NlpA lipoprotein family
IUJ44_RS14075	COG0765	amino acid transport
IUJ44_RS14080	COG0765	amino acid transport
IUJ44_RS14085	COG1126	abc transporter atp-binding protein
IUJ44_RS14095	COG1522	sequence-specific DNA binding
IUJ44_RS14110	COG1309	transcriptional regulator
IUJ44_RS14115	COG1484	DNA-dependent DNA replication
IUJ44_RS14120	COG4584	PFAM Integrase catalytic
IUJ44_RS14135	COG1002	Type II restriction enzyme, methylase subunits
IUJ44_RS14140	COG1061	Type III restriction enzyme res subunit
IUJ44_RS14150	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IUJ44_RS14180	COG0583	DNA-binding transcription factor activity
IUJ44_RS14190	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
IUJ44_RS14200	COG0697	spore germination
IUJ44_RS14225	COG3121	Chaperone
IUJ44_RS14230	COG3539	Fimbrial protein
IUJ44_RS14255	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
IUJ44_RS14255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IUJ44_RS14300	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IUJ44_RS14310	COG2353	YceI-like domain
IUJ44_RS14320	COG3698	Phosphodiester glycosidase
IUJ44_RS14335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
IUJ44_RS14340	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IUJ44_RS14340	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
IUJ44_RS14340	COG0506	proline dehydrogenase activity
IUJ44_RS14350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IUJ44_RS14355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
IUJ44_RS14375	COG1132	(ABC) transporter
IUJ44_RS14380	COG3122	Protein conserved in bacteria
IUJ44_RS14385	COG3619	membrane
IUJ44_RS14395	COG0640	Transcriptional regulator
IUJ44_RS14405	COG2850	peptidyl-arginine hydroxylation
IUJ44_RS14410	COG0424	maF-like protein
IUJ44_RS14430	COG0191	fructose-bisphosphate aldolase activity
IUJ44_RS14435	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ44_RS14450	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
IUJ44_RS14460	COG1192	Involved in chromosome partitioning
IUJ44_RS14465	COG1475	DNA binding
IUJ44_RS14470	COG0811	peptide transport
IUJ44_RS14480	COG1132	(ABC) transporter
IUJ44_RS14485	COG1663	tetraacyldisaccharide 4'-kinase activity
IUJ44_RS14505	COG0084	hydrolase, TatD family'
IUJ44_RS14570	COG0776	regulation of translation
IUJ44_RS14600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IUJ44_RS14605	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
IUJ44_RS14635	COG4206	TonB-dependent receptor
IUJ44_RS14655	COG0339	signal peptide processing
IUJ44_RS14665	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IUJ44_RS14700	COG0702	epimerase
IUJ44_RS14705	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ44_RS14725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IUJ44_RS14755	COG0316	Belongs to the HesB IscA family
IUJ44_RS14760	COG0822	iron-sulfur transferase activity
IUJ44_RS14785	COG0776	regulation of translation
IUJ44_RS14790	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IUJ44_RS14795	COG2207	Transcriptional regulator
IUJ44_RS14800	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ44_RS14805	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS14810	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS14825	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IUJ44_RS14845	COG4264	IucA IucC family
IUJ44_RS14850	COG4264	IucA IucC family
IUJ44_RS14860	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
IUJ44_RS14890	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IUJ44_RS14910	COG0406	alpha-ribazole phosphatase activity
IUJ44_RS14925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IUJ44_RS14930	COG0730	response to heat
IUJ44_RS14950	COG4773	Receptor
IUJ44_RS14955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ44_RS14970	COG1131	(ABC) transporter
IUJ44_RS14975	COG0842	Transport permease protein
IUJ44_RS14980	COG0842	Transport permease protein
IUJ44_RS15035	COG2226	methyltransferase
IUJ44_RS15060	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IUJ44_RS15080	COG3706	GGDEF domain
IUJ44_RS15095	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IUJ44_RS15100	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
IUJ44_RS15105	COG0022	dehydrogenase e1 component
IUJ44_RS15110	COG0508	dehydrogenase complex catalyzes the overall conversion of
IUJ44_RS15115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ44_RS15125	COG1063	alcohol dehydrogenase
IUJ44_RS15130	COG3781	membrane
IUJ44_RS15140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ44_RS15140	COG3453	Protein conserved in bacteria
IUJ44_RS15155	COG0730	response to heat
IUJ44_RS15170	COG2207	Transcriptional regulator
IUJ44_RS15170	COG3708	Transcriptional regulator
IUJ44_RS15175	COG1733	regulation of RNA biosynthetic process
IUJ44_RS15180	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
IUJ44_RS15190	COG2188	Transcriptional regulator
IUJ44_RS15205	COG4521	taurine ABC transporter
IUJ44_RS15210	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
IUJ44_RS15230	COG0477	Major facilitator Superfamily
IUJ44_RS15240	COG1027	Aspartate ammonia-lyase
IUJ44_RS15255	COG0583	DNA-binding transcription factor activity
IUJ44_RS15260	COG0583	DNA-binding transcription factor activity
IUJ44_RS15265	COG0183	Belongs to the thiolase family
IUJ44_RS15270	COG2031	fatty acid transporter
IUJ44_RS15285	COG0583	DNA-binding transcription factor activity
IUJ44_RS15305	COG1309	transcriptional regulator
IUJ44_RS15315	COG2610	gluconate transmembrane transporter activity
IUJ44_RS15320	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS15325	COG2207	Transcriptional regulator
IUJ44_RS15340	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS15350	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ44_RS15365	COG0543	2 iron, 2 sulfur cluster binding
IUJ44_RS15365	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IUJ44_RS15370	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
IUJ44_RS15375	COG4638	Rieske (2fe-2S)
IUJ44_RS15385	COG0725	ABC transporter, periplasmic molybdate-binding protein
IUJ44_RS15390	COG4149	molybdate abc transporter
IUJ44_RS15395	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
IUJ44_RS15400	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS15405	COG1535	isochorismatase
IUJ44_RS15405	COG3433	isochorismatase activity
IUJ44_RS15465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IUJ44_RS15480	COG0753	catalase activity
IUJ44_RS15490	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
IUJ44_RS15530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IUJ44_RS15535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ44_RS15540	COG0745	RESPONSE REGULATOR receiver
IUJ44_RS15545	COG2205	protein histidine kinase activity
IUJ44_RS15555	COG2207	Transcriptional regulator
IUJ44_RS15570	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS15585	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
IUJ44_RS15635	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
IUJ44_RS15705	COG1401	restriction endodeoxyribonuclease activity
IUJ44_RS15750	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IUJ44_RS15770	COG1120	ATPase activity
IUJ44_RS15775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IUJ44_RS15785	COG1064	alcohol dehydrogenase
IUJ44_RS15800	COG2207	Transcriptional regulator
IUJ44_RS15805	COG2084	Dehydrogenase
IUJ44_RS15815	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IUJ44_RS15820	COG0583	DNA-binding transcription factor activity
IUJ44_RS15830	COG0129	dihydroxy-acid dehydratase activity
IUJ44_RS15835	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS15850	COG1566	PFAM secretion protein HlyD family protein
IUJ44_RS15865	COG0583	DNA-binding transcription factor activity
IUJ44_RS15880	COG2188	Transcriptional regulator
IUJ44_RS15915	COG3210	domain, Protein
IUJ44_RS15920	COG2831	hemolysin activation secretion protein
IUJ44_RS15940	COG0318	PFAM AMP-dependent synthetase and ligase
IUJ44_RS15950	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS15960	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS15965	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS15970	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS15975	COG0583	DNA-binding transcription factor activity
IUJ44_RS15980	COG1309	transcriptional regulator
IUJ44_RS16005	COG0789	Transcriptional regulator
IUJ44_RS16020	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ44_RS16020	COG1902	pentaerythritol trinitrate reductase activity
IUJ44_RS16035	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS16055	COG2186	Transcriptional regulator
IUJ44_RS16065	COG0583	DNA-binding transcription factor activity
IUJ44_RS16070	COG4948	Mandelate Racemase Muconate Lactonizing
IUJ44_RS16075	COG4829	muconolactone delta-isomerase
IUJ44_RS16085	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IUJ44_RS16090	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ44_RS16095	COG0183	Belongs to the thiolase family
IUJ44_RS16100	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
IUJ44_RS16110	COG1012	belongs to the aldehyde dehydrogenase family
IUJ44_RS16120	COG3733	amine oxidase
IUJ44_RS16130	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ44_RS16140	COG1028	Short-chain dehydrogenase reductase Sdr
IUJ44_RS16150	COG4638	Rieske (2fe-2S)
IUJ44_RS16170	COG0154	amidase activity
IUJ44_RS16180	COG2814	Major facilitator Superfamily
IUJ44_RS16205	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS16210	COG0583	DNA-binding transcription factor activity
IUJ44_RS16215	COG1414	Transcriptional regulator
IUJ44_RS16230	COG2391	methyltransferase activity
IUJ44_RS16240	COG4993	Dehydrogenase
IUJ44_RS16245	COG3659	wide pore channel activity
IUJ44_RS16250	COG3420	alginic acid biosynthetic process
IUJ44_RS16255	COG0710	3-dehydroquinate dehydratase activity
IUJ44_RS16260	COG3485	protocatechuate 3,4-dioxygenase
IUJ44_RS16265	COG3485	protocatechuate 3,4-dioxygenase
IUJ44_RS16270	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IUJ44_RS16275	COG2271	Major facilitator Superfamily
IUJ44_RS16280	COG0596	Alpha beta hydrolase
IUJ44_RS16285	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IUJ44_RS16290	COG0183	Belongs to the thiolase family
IUJ44_RS16295	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
IUJ44_RS16300	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
IUJ44_RS16310	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IUJ44_RS16315	COG2323	membrane
IUJ44_RS16360	COG1902	pentaerythritol trinitrate reductase activity
IUJ44_RS16360	COG0446	pyridine nucleotide-disulphide oxidoreductase
IUJ44_RS16385	COG0542	response to heat
IUJ44_RS16390	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
IUJ44_RS16420	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IUJ44_RS16425	COG0569	domain protein
IUJ44_RS16430	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IUJ44_RS16445	COG4774	siderophore transport
IUJ44_RS16450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IUJ44_RS16460	COG1585	Membrane protein implicated in regulation of membrane protease activity
IUJ44_RS16475	COG1294	oxidase, subunit
IUJ44_RS16480	COG4890	Cyd operon protein YbgT
IUJ44_RS16490	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
IUJ44_RS16500	COG0552	protein localization to endoplasmic reticulum
IUJ44_RS16525	COG0517	IMP dehydrogenase activity
IUJ44_RS16525	COG0516	GMP reductase activity
IUJ44_RS16530	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IUJ44_RS16535	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IUJ44_RS16545	COG0583	DNA-binding transcription factor activity
IUJ44_RS16550	COG0024	Methionine aminopeptidase
IUJ44_RS16580	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IUJ44_RS16580	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IUJ44_RS16585	COG1105	Belongs to the carbohydrate kinase PfkB family
IUJ44_RS16590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ44_RS16590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IUJ44_RS16590	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
IUJ44_RS16610	COG3300	MHYT domain
IUJ44_RS16610	COG5001	Diguanylate cyclase
IUJ44_RS16625	COG2135	peptidase activity
IUJ44_RS16630	COG0659	secondary active sulfate transmembrane transporter activity
IUJ44_RS16650	COG1113	amino acid transport
IUJ44_RS16660	COG1522	sequence-specific DNA binding
IUJ44_RS16685	COG1011	Hydrolase
IUJ44_RS16690	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IUJ44_RS16700	COG2137	regulation of response to DNA damage stimulus
IUJ44_RS16715	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ44_RS16750	COG0575	Belongs to the CDS family
IUJ44_RS16755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IUJ44_RS16780	COG3852	Histidine kinase
IUJ44_RS16785	COG2204	response regulator
IUJ44_RS16840	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IUJ44_RS16845	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
IUJ44_RS16865	COG0697	spore germination
IUJ44_RS16870	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ44_RS16880	COG0303	'Molybdopterin
IUJ44_RS16885	COG0521	Mo-molybdopterin cofactor biosynthetic process
IUJ44_RS16885	COG0315	cyclic pyranopterin monophosphate synthase activity
IUJ44_RS16900	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IUJ44_RS16915	COG0243	molybdopterin cofactor binding
IUJ44_RS16920	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ44_RS16925	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
IUJ44_RS16925	COG2146	nitrite reductase [NAD(P)H] activity
IUJ44_RS16935	COG0745	RESPONSE REGULATOR receiver
IUJ44_RS16940	COG1116	anion transmembrane transporter activity
IUJ44_RS16940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IUJ44_RS16960	COG0511	ligase activity, forming carbon-carbon bonds
IUJ44_RS16975	COG2814	Major facilitator Superfamily
IUJ44_RS16995	COG0069	glutamate synthase activity
IUJ44_RS17015	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
IUJ44_RS17025	COG1454	alcohol dehydrogenase
IUJ44_RS17030	COG0824	Thioesterase
IUJ44_RS17045	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IUJ44_RS17065	COG2030	dehydratase
IUJ44_RS17075	COG0183	Belongs to the thiolase family
IUJ44_RS17085	COG0583	DNA-binding transcription factor activity
IUJ44_RS17090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IUJ44_RS17100	COG1522	sequence-specific DNA binding
IUJ44_RS17105	COG3135	benzoate transporter
IUJ44_RS17115	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IUJ44_RS17140	COG0589	response to stress
IUJ44_RS17145	COG0488	(ABC) transporter
IUJ44_RS17165	COG4773	Receptor
IUJ44_RS17195	COG0668	transmembrane transport
IUJ44_RS17205	COG1309	transcriptional regulator
IUJ44_RS17225	COG1605	Chorismate mutase
IUJ44_RS17265	COG0308	aminopeptidase N
IUJ44_RS17290	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IUJ44_RS17295	COG1454	alcohol dehydrogenase
IUJ44_RS17315	COG0531	amino acid
IUJ44_RS17320	COG4303	Ethanolamine ammonia lyase large subunit
IUJ44_RS17325	COG4302	ethanolamine ammonia-lyase activity
IUJ44_RS17330	COG0519	Catalyzes the synthesis of GMP from XMP
IUJ44_RS17330	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IUJ44_RS17335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IUJ44_RS17345	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IUJ44_RS17360	COG0697	spore germination
IUJ44_RS17365	COG1923	regulation of RNA biosynthetic process
IUJ44_RS17375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IUJ44_RS17380	COG0802	atpase or kinase
IUJ44_RS17400	COG1187	pseudouridine synthase activity
IUJ44_RS17415	COG0583	DNA-binding transcription factor activity
IUJ44_RS17430	COG2814	Major facilitator Superfamily
IUJ44_RS17435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IUJ44_RS17460	COG0729	surface antigen
IUJ44_RS17480	COG0174	glutamine synthetase
IUJ44_RS17485	COG0745	RESPONSE REGULATOR receiver
IUJ44_RS17490	COG2205	protein histidine kinase activity
IUJ44_RS17500	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
IUJ44_RS17505	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
IUJ44_RS17530	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IUJ44_RS17535	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
IUJ44_RS17570	COG0583	DNA-binding transcription factor activity
IUJ44_RS17585	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IUJ44_RS17595	COG3658	cytochrome
IUJ44_RS17600	COG1215	transferase activity, transferring glycosyl groups
IUJ44_RS17605	COG1649	PFAM Uncharacterised BCR, COG1649
IUJ44_RS17605	COG0726	polysaccharide deacetylase
IUJ44_RS17630	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
IUJ44_RS17635	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
IUJ44_RS17645	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
IUJ44_RS17670	COG0305	Participates in initiation and elongation during chromosome replication
IUJ44_RS17675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IUJ44_RS17685	COG1305	Transglutaminase-like
IUJ44_RS17695	COG2308	Evidence 4 Homologs of previously reported genes of
IUJ44_RS17725	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
IUJ44_RS17730	COG0138	bifunctional purine biosynthesis protein purh
IUJ44_RS17735	COG0151	Belongs to the GarS family
IUJ44_RS17740	COG1464	Belongs to the NlpA lipoprotein family
IUJ44_RS17745	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IUJ44_RS17750	COG2011	ABC-type metal ion transport system permease component
IUJ44_RS17755	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IUJ44_RS17765	COG1301	dicarboxylic acid transport
IUJ44_RS17795	COG1794	racemase activity, acting on amino acids and derivatives
IUJ44_RS17815	COG0745	RESPONSE REGULATOR receiver
IUJ44_RS17820	COG0642	Histidine kinase
IUJ44_RS17825	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ44_RS17835	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
IUJ44_RS17875	COG2351	hydroxyisourate hydrolase activity
IUJ44_RS17885	COG3008	intermembrane lipid transfer
IUJ44_RS17885	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IUJ44_RS17890	COG2995	paraquat-inducible protein a
IUJ44_RS17920	COG1051	belongs to the nudix hydrolase family
IUJ44_RS17925	COG0477	Major facilitator Superfamily
IUJ44_RS17980	COG2186	Transcriptional regulator
IUJ44_RS17990	COG0786	glutamate:sodium symporter activity
IUJ44_RS17995	COG3243	poly(R)-hydroxyalkanoic acid synthase
IUJ44_RS18020	COG3111	PFAM Bacterial OB fold (BOF) protein
IUJ44_RS18120	COG1610	YqeY-like protein
IUJ44_RS18125	COG4783	chaperone-mediated protein folding
IUJ44_RS18150	COG1286	toxin biosynthetic process
IUJ44_RS18180	COG0778	Nitroreductase
IUJ44_RS18190	COG0513	Belongs to the DEAD box helicase family
IUJ44_RS18215	COG2363	Small membrane protein
IUJ44_RS18245	COG1234	tRNA 3'-trailer cleavage
IUJ44_RS18250	COG2195	Cleaves the N-terminal amino acid of tripeptides
IUJ44_RS18260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IUJ44_RS18270	COG2819	hydrolase of the alpha beta superfamily
IUJ44_RS18275	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS18280	COG1301	dicarboxylic acid transport
IUJ44_RS18285	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IUJ44_RS18290	COG3139	Protein of unknown function (DUF1315)
IUJ44_RS18295	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
IUJ44_RS18300	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IUJ44_RS18310	COG0494	nUDIX hydrolase
IUJ44_RS18320	COG0642	Histidine kinase
IUJ44_RS18330	COG3111	PFAM Bacterial OB fold (BOF) protein
IUJ44_RS18335	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IUJ44_RS18345	COG1720	tRNA m6t6A37 methyltransferase activity
IUJ44_RS18360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IUJ44_RS18365	COG0826	peptidase U32
IUJ44_RS18370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
IUJ44_RS18380	COG4598	ABC transporter
IUJ44_RS18385	COG4160	amino acid transport
IUJ44_RS18390	COG4215	(ABC) transporter
IUJ44_RS18405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IUJ44_RS18510	COG3561	AntA/AntB antirepressor
IUJ44_RS18775	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IUJ44_RS18805	COG3617	BRO family, N-terminal domain
IUJ44_RS18810	COG0582	viral genome integration into host DNA
IUJ44_RS18815	COG1131	(ABC) transporter
IUJ44_RS18820	COG0842	Transport permease protein
IUJ44_RS18835	COG0772	Belongs to the SEDS family
IUJ44_RS18840	COG2951	lytic endotransglycosylase activity
IUJ44_RS18865	COG2207	Transcriptional regulator
IUJ44_RS18880	COG0052	Belongs to the universal ribosomal protein uS2 family
IUJ44_RS18885	COG0024	Methionine aminopeptidase
IUJ44_RS18895	COG2223	nitrite transmembrane transporter activity
IUJ44_RS18905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IUJ44_RS18910	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IUJ44_RS18915	COG1960	acyl-CoA dehydrogenase activity
IUJ44_RS18930	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
IUJ44_RS18935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IUJ44_RS18940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IUJ44_RS18960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IUJ44_RS18965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IUJ44_RS18970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IUJ44_RS19005	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
IUJ44_RS19015	COG0174	glutamine synthetase
IUJ44_RS19030	COG0512	Glutamine amidotransferase of anthranilate synthase
IUJ44_RS19035	COG0308	aminopeptidase N