locus-tag	class	description
B7L45_RS00040	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B7L45_RS00045	COG1596	polysaccharide export
B7L45_RS00070	COG0728	peptidoglycan biosynthetic process
B7L45_RS00075	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7L45_RS00125	COG0546	phosphoglycolate phosphatase activity
B7L45_RS00130	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS00150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L45_RS00155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L45_RS00160	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7L45_RS00165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L45_RS00170	COG1116	anion transmembrane transporter activity
B7L45_RS00175	COG1309	transcriptional regulator
B7L45_RS00180	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7L45_RS00190	COG0196	riboflavin kinase activity
B7L45_RS00195	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B7L45_RS00205	COG1047	Peptidyl-prolyl cis-trans
B7L45_RS00245	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7L45_RS00250	COG0657	acetylesterase activity
B7L45_RS00270	COG0583	DNA-binding transcription factor activity
B7L45_RS00300	COG2951	lytic endotransglycosylase activity
B7L45_RS00305	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B7L45_RS00325	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7L45_RS00335	COG0671	phosphoesterase, PA-phosphatase related
B7L45_RS00340	COG0861	Integral membrane protein TerC family
B7L45_RS00350	COG0754	glutathionylspermidine amidase activity
B7L45_RS00360	COG0402	S-adenosylhomocysteine deaminase activity
B7L45_RS00375	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L45_RS00380	COG1230	cation diffusion facilitator family transporter
B7L45_RS00395	COG0706	membrane insertase activity
B7L45_RS00420	COG0592	DNA-directed DNA polymerase activity
B7L45_RS00430	COG0187	DNA topoisomerase II activity
B7L45_RS00440	COG0586	Pfam SNARE associated Golgi protein
B7L45_RS00445	COG0488	(ABC) transporter
B7L45_RS00470	COG0596	Alpha beta hydrolase
B7L45_RS00475	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B7L45_RS00480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B7L45_RS00520	COG0733	neurotransmitter:sodium symporter activity
B7L45_RS00570	COG2233	PERMEase
B7L45_RS00585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L45_RS00620	COG2814	Major facilitator Superfamily
B7L45_RS00625	COG0656	L-ascorbic acid biosynthetic process
B7L45_RS00630	COG0583	DNA-binding transcription factor activity
B7L45_RS00640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L45_RS00645	COG1064	alcohol dehydrogenase
B7L45_RS00650	COG2818	Glycosylase
B7L45_RS00665	COG1194	a g-specific adenine glycosylase
B7L45_RS00685	COG2983	Belongs to the UPF0260 family
B7L45_RS00690	COG2133	pyrroloquinoline quinone binding
B7L45_RS00695	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7L45_RS00700	COG2116	formate transmembrane transporter activity
B7L45_RS00720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L45_RS00725	COG1335	isochorismatase
B7L45_RS00730	COG0385	Bile acid
B7L45_RS00735	COG0534	Mate efflux family protein
B7L45_RS00740	COG1683	Conserved Protein
B7L45_RS00760	COG0625	glutathione transferase activity
B7L45_RS00770	COG1113	amino acid transport
B7L45_RS00780	COG0523	cobalamin synthesis protein
B7L45_RS00790	COG2188	Transcriptional regulator
B7L45_RS00820	COG0010	Belongs to the arginase family
B7L45_RS00835	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7L45_RS00840	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7L45_RS00850	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B7L45_RS00855	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B7L45_RS00965	COG0534	Mate efflux family protein
B7L45_RS00970	COG0436	Aminotransferase
B7L45_RS00975	COG2733	membrane
B7L45_RS00990	COG2918	glutathione biosynthetic process
B7L45_RS01005	COG0791	NLP P60 protein
B7L45_RS01005	COG1388	LysM domain
B7L45_RS01020	COG3150	esterase
B7L45_RS01030	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS01035	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
B7L45_RS01045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L45_RS01055	COG2233	PERMEase
B7L45_RS01060	COG2351	hydroxyisourate hydrolase activity
B7L45_RS01095	COG3706	GGDEF domain
B7L45_RS01110	COG1393	Belongs to the ArsC family
B7L45_RS01115	COG0708	Exodeoxyribonuclease III
B7L45_RS01135	COG0189	ligase activity
B7L45_RS01155	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B7L45_RS01165	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B7L45_RS01180	COG4942	peptidase
B7L45_RS01190	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7L45_RS01200	COG2119	membrane
B7L45_RS01205	COG4774	siderophore transport
B7L45_RS01210	COG0426	domain, Protein
B7L45_RS01210	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L45_RS01235	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B7L45_RS01255	COG1902	pentaerythritol trinitrate reductase activity
B7L45_RS01260	COG1519	Transferase
B7L45_RS01265	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7L45_RS01270	COG0668	transmembrane transport
B7L45_RS01280	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7L45_RS01285	COG1335	isochorismatase
B7L45_RS01290	COG1522	sequence-specific DNA binding
B7L45_RS01295	COG3328	transposase activity
B7L45_RS01320	COG2198	Histidine kinase
B7L45_RS01320	COG0784	Response regulator, receiver
B7L45_RS01320	COG2205	protein histidine kinase activity
B7L45_RS01325	COG3162	membrane
B7L45_RS01330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7L45_RS01340	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L45_RS01360	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7L45_RS01365	COG1309	transcriptional regulator
B7L45_RS01385	COG0351	phosphomethylpyrimidine kinase
B7L45_RS01385	COG0352	thiamine-phosphate diphosphorylase activity
B7L45_RS01385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B7L45_RS01395	COG2814	Major facilitator Superfamily
B7L45_RS01410	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7L45_RS01420	COG1113	amino acid transport
B7L45_RS01430	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7L45_RS01435	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS01445	COG1335	isochorismatase
B7L45_RS01475	COG2814	Major facilitator Superfamily
B7L45_RS01480	COG0583	DNA-binding transcription factor activity
B7L45_RS01500	COG0667	Aldo Keto reductase
B7L45_RS01535	COG1733	regulation of RNA biosynthetic process
B7L45_RS01545	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L45_RS01610	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7L45_RS01625	COG2329	Antibiotic biosynthesis monooxygenase
B7L45_RS01655	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7L45_RS01685	COG0427	acetyl-CoA hydrolase
B7L45_RS01705	COG0659	secondary active sulfate transmembrane transporter activity
B7L45_RS01710	COG4221	oxidoreductase activity
B7L45_RS01715	COG2873	o-acetylhomoserine
B7L45_RS01720	COG0488	(ABC) transporter
B7L45_RS01800	COG0833	amino acid
B7L45_RS01845	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B7L45_RS01850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B7L45_RS01865	COG2226	methyltransferase
B7L45_RS01915	COG0070	glutamate synthase
B7L45_RS01915	COG0067	glutamate synthase
B7L45_RS01915	COG0069	glutamate synthase activity
B7L45_RS01920	COG0493	'glutamate synthase
B7L45_RS01930	COG1704	LemA family
B7L45_RS01935	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B7L45_RS01955	COG3307	-O-antigen
B7L45_RS01975	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7L45_RS01985	COG0194	GDP metabolic process
B7L45_RS02035	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B7L45_RS02055	COG5380	lipid catabolic process
B7L45_RS02060	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B7L45_RS02085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7L45_RS02090	COG0277	FAD linked oxidase domain protein
B7L45_RS02100	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B7L45_RS02105	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L45_RS02120	COG1289	transmembrane transporter activity
B7L45_RS02130	COG0628	permease
B7L45_RS02135	COG1192	Involved in chromosome partitioning
B7L45_RS02165	COG0833	amino acid
B7L45_RS02170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7L45_RS02175	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7L45_RS02185	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS02225	COG0583	DNA-binding transcription factor activity
B7L45_RS02270	COG0517	IMP dehydrogenase activity
B7L45_RS02275	COG1983	PspC domain protein
B7L45_RS02285	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS02300	COG0408	coproporphyrinogen oxidase activity
B7L45_RS02320	COG0513	Belongs to the DEAD box helicase family
B7L45_RS02325	COG1127	ABC transporter
B7L45_RS02330	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7L45_RS02340	COG2854	intermembrane phospholipid transfer
B7L45_RS02350	COG0598	Magnesium transport protein CorA
B7L45_RS02360	COG0494	nUDIX hydrolase
B7L45_RS02365	COG1040	competence protein
B7L45_RS02370	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7L45_RS02390	COG1946	Acyl-CoA thioesterase
B7L45_RS02395	COG1301	dicarboxylic acid transport
B7L45_RS02410	COG1959	2 iron, 2 sulfur cluster binding
B7L45_RS02415	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L45_RS02415	COG1017	nitric oxide dioxygenase activity
B7L45_RS02420	COG0433	COG0433 Predicted ATPase
B7L45_RS02425	COG0626	cystathionine gamma-synthase activity
B7L45_RS02580	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS02585	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B7L45_RS02615	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
B7L45_RS02620	COG0339	signal peptide processing
B7L45_RS02625	COG0557	exoribonuclease II activity
B7L45_RS02670	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7L45_RS02675	COG2169	Transcriptional regulator
B7L45_RS02680	COG0697	spore germination
B7L45_RS02685	COG1295	ribonuclease BN
B7L45_RS02720	COG1702	phosphate starvation-inducible protein PhoH
B7L45_RS02730	COG1196	nuclear chromosome segregation
B7L45_RS02730	COG0739	heme binding
B7L45_RS02730	COG0741	lytic transglycosylase activity
B7L45_RS02760	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B7L45_RS02765	COG1183	phosphatidylcholine synthase activity
B7L45_RS02810	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS02815	COG1309	transcriptional regulator
B7L45_RS02830	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7L45_RS02835	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS02855	COG2969	positive regulation of protein catabolic process
B7L45_RS02865	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B7L45_RS02875	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B7L45_RS02880	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B7L45_RS02885	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7L45_RS02905	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7L45_RS02915	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7L45_RS02920	COG1408	metallophosphoesterase
B7L45_RS02930	COG2199	diguanylate cyclase activity
B7L45_RS02990	COG1607	acyl-coa hydrolase
B7L45_RS03020	COG2350	Protein conserved in bacteria
B7L45_RS03030	COG0613	PHP domain protein
B7L45_RS03035	COG3781	membrane
B7L45_RS03045	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7L45_RS03050	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7L45_RS03060	COG1862	Preprotein translocase
B7L45_RS03090	COG2205	protein histidine kinase activity
B7L45_RS03095	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B7L45_RS03115	COG0726	polysaccharide deacetylase
B7L45_RS03120	COG0463	Glycosyl transferase, family 2
B7L45_RS03125	COG0438	transferase activity, transferring glycosyl groups
B7L45_RS03190	COG0625	glutathione transferase activity
B7L45_RS03195	COG0583	DNA-binding transcription factor activity
B7L45_RS03200	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS03205	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS03215	COG2205	protein histidine kinase activity
B7L45_RS03220	COG0745	RESPONSE REGULATOR receiver
B7L45_RS03225	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B7L45_RS03245	COG2096	Adenosyltransferase
B7L45_RS03295	COG0285	dihydrofolate synthase activity
B7L45_RS03315	COG0450	alkyl hydroperoxide reductase
B7L45_RS03330	COG0477	Major facilitator Superfamily
B7L45_RS03335	COG1272	protein, Hemolysin III
B7L45_RS03370	COG0183	Belongs to the thiolase family
B7L45_RS03375	COG2207	Transcriptional regulator
B7L45_RS03395	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L45_RS03415	COG0183	Belongs to the thiolase family
B7L45_RS03425	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B7L45_RS03425	COG2885	chlorophyll binding
B7L45_RS03435	COG1690	Belongs to the RtcB family
B7L45_RS03440	COG0833	amino acid
B7L45_RS03450	COG2233	PERMEase
B7L45_RS03455	COG1217	gtp-binding protein TYPA
B7L45_RS03480	COG2094	Belongs to the DNA glycosylase MPG family
B7L45_RS03485	COG4772	TonB-dependent receptor
B7L45_RS03495	COG4772	TonB-dependent receptor
B7L45_RS03500	COG1902	pentaerythritol trinitrate reductase activity
B7L45_RS03515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L45_RS03520	COG0354	folic acid binding
B7L45_RS03530	COG3189	MarR family transcriptional regulator
B7L45_RS03535	COG2824	Alkylphosphonate utilization operon protein PhnA
B7L45_RS03540	COG3422	double-strand break repair
B7L45_RS03580	COG0840	transmembrane signaling receptor activity
B7L45_RS03600	COG5510	response to toxic substance
B7L45_RS03610	COG2832	Protein of unknown function (DUF454)
B7L45_RS03615	COG1376	ErfK ybiS ycfS ynhG family protein
B7L45_RS03655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B7L45_RS03665	COG1289	transmembrane transporter activity
B7L45_RS03670	COG2814	Major facilitator Superfamily
B7L45_RS03685	COG1115	amino acid carrier protein
B7L45_RS03690	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7L45_RS03695	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7L45_RS03700	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
B7L45_RS03730	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7L45_RS03740	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7L45_RS03745	COG1077	Cell shape determining protein MreB Mrl
B7L45_RS03750	COG1792	Involved in formation and maintenance of cell shape
B7L45_RS03755	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B7L45_RS03760	COG0424	maF-like protein
B7L45_RS03765	COG1530	ribonuclease E activity
B7L45_RS03770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L45_RS03780	COG0560	Phosphoserine phosphatase
B7L45_RS03790	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L45_RS03815	COG2207	Transcriptional regulator
B7L45_RS03835	COG1113	amino acid transport
B7L45_RS03840	COG2828	Protein conserved in bacteria
B7L45_RS03845	COG0142	geranyltranstransferase activity
B7L45_RS03850	COG2315	Protein conserved in bacteria
B7L45_RS03865	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7L45_RS03885	COG2194	sulfuric ester hydrolase activity
B7L45_RS03890	COG0745	RESPONSE REGULATOR receiver
B7L45_RS03895	COG0642	Histidine kinase
B7L45_RS03905	COG0004	ammonium transporteR
B7L45_RS03915	COG0583	DNA-binding transcription factor activity
B7L45_RS03935	COG0525	valine-tRNA ligase activity
B7L45_RS03945	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS03955	COG0393	Putative heavy-metal-binding
B7L45_RS03960	COG0393	Putative heavy-metal-binding
B7L45_RS03965	COG1538	Outer membrane efflux protein
B7L45_RS03975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L45_RS03980	COG0671	phosphoesterase, PA-phosphatase related
B7L45_RS04010	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B7L45_RS04025	COG1648	precorrin-2 dehydrogenase activity
B7L45_RS04025	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7L45_RS04030	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B7L45_RS04035	COG1733	regulation of RNA biosynthetic process
B7L45_RS04045	COG0531	amino acid
B7L45_RS04060	COG0321	lipoyl(octanoyl) transferase activity
B7L45_RS04065	COG2921	Belongs to the UPF0250 family
B7L45_RS04105	COG2009	succinate dehydrogenase
B7L45_RS04110	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B7L45_RS04115	COG1053	succinate dehydrogenase
B7L45_RS04120	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7L45_RS04140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7L45_RS04160	COG2354	Protein conserved in bacteria
B7L45_RS04165	COG2321	neutral zinc metallopeptidase
B7L45_RS04195	COG2843	Capsule synthesis protein
B7L45_RS04210	COG0589	response to stress
B7L45_RS04230	COG0505	Belongs to the CarA family
B7L45_RS04260	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7L45_RS04265	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7L45_RS04315	COG0477	Major facilitator Superfamily
B7L45_RS04320	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7L45_RS04335	COG1597	lipid kinase activity
B7L45_RS04340	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7L45_RS04380	COG0584	glycerophosphoryl diester phosphodiesterase
B7L45_RS04400	COG0741	lytic transglycosylase activity
B7L45_RS04425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7L45_RS04440	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L45_RS04515	COG3267	Type II secretory pathway component ExeA
B7L45_RS04515	COG3409	Peptidoglycan-binding domain 1 protein
B7L45_RS04540	COG0681	Belongs to the peptidase S26 family
B7L45_RS04590	COG4383	Mu-like prophage protein gp29
B7L45_RS04595	COG2369	cell adhesion
B7L45_RS04600	COG5005	Phage virion morphogenesis
B7L45_RS04615	COG4397	Mu-like prophage major head subunit gpT
B7L45_RS04710	COG0778	Nitroreductase
B7L45_RS04725	COG1929	Belongs to the glycerate kinase type-1 family
B7L45_RS04730	COG0243	molybdopterin cofactor binding
B7L45_RS04735	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B7L45_RS04740	COG3339	Conserved Protein
B7L45_RS04750	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
B7L45_RS04765	COG1113	amino acid transport
B7L45_RS04775	COG0019	diaminopimelate decarboxylase activity
B7L45_RS04785	COG1280	lysine exporter protein (LysE YggA)
B7L45_RS04790	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B7L45_RS04820	COG0463	Glycosyl transferase, family 2
B7L45_RS04840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L45_RS04870	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7L45_RS04875	COG1136	(ABC) transporter
B7L45_RS04880	COG0658	competence protein
B7L45_RS04880	COG2333	competence protein COMEC
B7L45_RS04890	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B7L45_RS04890	COG0616	signal peptide processing
B7L45_RS04895	COG0596	Alpha beta hydrolase
B7L45_RS04900	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B7L45_RS04910	COG0628	permease
B7L45_RS04960	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7L45_RS04980	COG0823	Involved in the tonB-independent uptake of proteins
B7L45_RS05000	COG0824	Thioesterase
B7L45_RS05005	COG1473	amidohydrolase
B7L45_RS05025	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7L45_RS05025	COG0047	phosphoribosylformylglycinamidine synthase activity
B7L45_RS05030	COG2814	Major facilitator Superfamily
B7L45_RS05040	COG1024	Enoyl-CoA hydratase
B7L45_RS05045	COG1051	belongs to the nudix hydrolase family
B7L45_RS05045	COG1056	cytidyltransferase-related domain
B7L45_RS05055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B7L45_RS05070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B7L45_RS05085	COG4625	pathogenesis
B7L45_RS05090	COG0583	DNA-binding transcription factor activity
B7L45_RS05095	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B7L45_RS05100	COG4208	sulfate ABC transporter
B7L45_RS05105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B7L45_RS05115	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B7L45_RS05120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7L45_RS05125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7L45_RS05145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7L45_RS05160	COG0681	Belongs to the peptidase S26 family
B7L45_RS05175	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B7L45_RS05185	COG1381	Involved in DNA repair and RecF pathway recombination
B7L45_RS05190	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B7L45_RS05200	COG4221	oxidoreductase activity
B7L45_RS05225	COG0436	Aminotransferase
B7L45_RS05245	COG0556	nucleotide-excision repair
B7L45_RS05300	COG2070	2-Nitropropane dioxygenase
B7L45_RS05330	COG1215	transferase activity, transferring glycosyl groups
B7L45_RS05345	COG0415	Belongs to the DNA photolyase family
B7L45_RS05355	COG1252	NADH dehydrogenase
B7L45_RS05360	COG1686	Belongs to the peptidase S11 family
B7L45_RS05375	COG1187	pseudouridine synthase activity
B7L45_RS05395	COG0477	Major facilitator Superfamily
B7L45_RS05400	COG0583	DNA-binding transcription factor activity
B7L45_RS05405	COG1823	symporter activity
B7L45_RS05415	COG0612	Peptidase, M16
B7L45_RS05440	COG0352	thiamine-phosphate diphosphorylase activity
B7L45_RS05475	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L45_RS05490	COG1309	transcriptional regulator
B7L45_RS05500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7L45_RS05505	COG0076	glutamate decarboxylase activity
B7L45_RS05515	COG1522	sequence-specific DNA binding
B7L45_RS05520	COG3961	Belongs to the TPP enzyme family
B7L45_RS05525	COG1113	amino acid transport
B7L45_RS05530	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7L45_RS05535	COG0573	inorganic phosphate transmembrane transporter activity
B7L45_RS05545	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7L45_RS05550	COG0616	signal peptide processing
B7L45_RS05585	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B7L45_RS05590	COG1686	Belongs to the peptidase S11 family
B7L45_RS05615	COG0583	DNA-binding transcription factor activity
B7L45_RS05620	COG1067	ATP-dependent peptidase activity
B7L45_RS05665	COG1966	Carbon starvation protein
B7L45_RS05670	COG2879	small protein
B7L45_RS05710	COG2508	Transcriptional regulator
B7L45_RS05710	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B7L45_RS05730	COG1113	amino acid transport
B7L45_RS05735	COG0583	DNA-binding transcription factor activity
B7L45_RS05740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L45_RS05745	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L45_RS05755	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS05760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L45_RS05765	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B7L45_RS05765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7L45_RS05800	COG2814	Major facilitator Superfamily
B7L45_RS05805	COG4948	Mandelate Racemase Muconate Lactonizing
B7L45_RS05815	COG1309	transcriptional regulator
B7L45_RS05835	COG1741	Belongs to the pirin family
B7L45_RS05845	COG2964	Protein conserved in bacteria
B7L45_RS05860	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L45_RS05865	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7L45_RS05870	COG4605	iron ion homeostasis
B7L45_RS05875	COG4604	ABC transporter, ATP-binding protein
B7L45_RS05880	COG4607	ABC-type enterochelin transport system periplasmic component
B7L45_RS05885	COG4774	siderophore transport
B7L45_RS05895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L45_RS05900	COG1021	2,3-dihydroxybenzoate-AMP ligase
B7L45_RS05905	COG3433	isochorismatase activity
B7L45_RS05905	COG1535	isochorismatase
B7L45_RS05915	COG1132	(ABC) transporter
B7L45_RS05920	COG1132	(ABC) transporter
B7L45_RS05925	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B7L45_RS05935	COG1169	isochorismate synthase
B7L45_RS05950	COG3739	integral membrane protein
B7L45_RS05975	COG0302	gtp cyclohydrolase
B7L45_RS05985	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7L45_RS06015	COG0308	aminopeptidase N
B7L45_RS06020	COG0512	Glutamine amidotransferase of anthranilate synthase
B7L45_RS06160	COG5410	chromosome segregation
B7L45_RS06300	COG0739	heme binding
B7L45_RS06510	COG5410	chromosome segregation
B7L45_RS06620	COG1598	PFAM Uncharacterised protein family UPF0150
B7L45_RS06675	COG0582	viral genome integration into host DNA
B7L45_RS06690	COG0174	glutamine synthetase
B7L45_RS06700	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B7L45_RS06735	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7L45_RS06740	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7L45_RS06745	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7L45_RS06765	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7L45_RS06770	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B7L45_RS06775	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B7L45_RS06790	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS06795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7L45_RS06800	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7L45_RS06810	COG2223	nitrite transmembrane transporter activity
B7L45_RS06820	COG0024	Methionine aminopeptidase
B7L45_RS06825	COG0052	Belongs to the universal ribosomal protein uS2 family
B7L45_RS06840	COG2207	Transcriptional regulator
B7L45_RS06865	COG2951	lytic endotransglycosylase activity
B7L45_RS06870	COG0772	Belongs to the SEDS family
B7L45_RS06885	COG0842	Transport permease protein
B7L45_RS06890	COG1131	(ABC) transporter
B7L45_RS06935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L45_RS06950	COG4215	(ABC) transporter
B7L45_RS06955	COG4160	amino acid transport
B7L45_RS06960	COG4598	ABC transporter
B7L45_RS06970	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7L45_RS06975	COG0826	peptidase U32
B7L45_RS06980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L45_RS06995	COG1720	tRNA m6t6A37 methyltransferase activity
B7L45_RS07005	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B7L45_RS07020	COG0642	Histidine kinase
B7L45_RS07030	COG0494	nUDIX hydrolase
B7L45_RS07040	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7L45_RS07045	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B7L45_RS07050	COG3139	Protein of unknown function (DUF1315)
B7L45_RS07055	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7L45_RS07065	COG1301	dicarboxylic acid transport
B7L45_RS07070	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS07075	COG2819	hydrolase of the alpha beta superfamily
B7L45_RS07085	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B7L45_RS07095	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7L45_RS07100	COG1234	tRNA 3'-trailer cleavage
B7L45_RS07130	COG2363	Small membrane protein
B7L45_RS07150	COG0513	Belongs to the DEAD box helicase family
B7L45_RS07160	COG0778	Nitroreductase
B7L45_RS07190	COG1286	toxin biosynthetic process
B7L45_RS07215	COG4783	chaperone-mediated protein folding
B7L45_RS07220	COG1610	YqeY-like protein
B7L45_RS07320	COG3111	PFAM Bacterial OB fold (BOF) protein
B7L45_RS07345	COG3243	poly(R)-hydroxyalkanoic acid synthase
B7L45_RS07350	COG0786	glutamate:sodium symporter activity
B7L45_RS07360	COG2186	Transcriptional regulator
B7L45_RS07410	COG0477	Major facilitator Superfamily
B7L45_RS07440	COG2985	domain, Protein
B7L45_RS07450	COG2995	paraquat-inducible protein a
B7L45_RS07455	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7L45_RS07455	COG3008	intermembrane lipid transfer
B7L45_RS07465	COG1794	racemase activity, acting on amino acids and derivatives
B7L45_RS07540	COG0482	sulfurtransferase activity
B7L45_RS07555	COG0488	(ABC) transporter
B7L45_RS07560	COG3173	Aminoglycoside phosphotransferase
B7L45_RS07570	COG2433	Pfam Transposase IS66
B7L45_RS07590	COG1301	dicarboxylic acid transport
B7L45_RS07600	COG1301	dicarboxylic acid transport
B7L45_RS07610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L45_RS07615	COG2011	ABC-type metal ion transport system permease component
B7L45_RS07620	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7L45_RS07625	COG1464	Belongs to the NlpA lipoprotein family
B7L45_RS07630	COG0151	Belongs to the GarS family
B7L45_RS07635	COG0138	bifunctional purine biosynthesis protein purh
B7L45_RS07640	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B7L45_RS07670	COG2308	Evidence 4 Homologs of previously reported genes of
B7L45_RS07680	COG1305	Transglutaminase-like
B7L45_RS07690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7L45_RS07695	COG0305	Participates in initiation and elongation during chromosome replication
B7L45_RS07720	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7L45_RS07730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7L45_RS07735	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B7L45_RS07760	COG1649	PFAM Uncharacterised BCR, COG1649
B7L45_RS07760	COG0726	polysaccharide deacetylase
B7L45_RS07765	COG1215	transferase activity, transferring glycosyl groups
B7L45_RS07780	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7L45_RS07800	COG0583	DNA-binding transcription factor activity
B7L45_RS07820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L45_RS07825	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L45_RS07840	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS07845	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7L45_RS07850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L45_RS07875	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B7L45_RS07880	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B7L45_RS07890	COG2205	protein histidine kinase activity
B7L45_RS07895	COG0745	RESPONSE REGULATOR receiver
B7L45_RS07900	COG0174	glutamine synthetase
B7L45_RS07920	COG0729	surface antigen
B7L45_RS07950	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7L45_RS07955	COG2814	Major facilitator Superfamily
B7L45_RS07970	COG0583	DNA-binding transcription factor activity
B7L45_RS07985	COG1187	pseudouridine synthase activity
B7L45_RS08005	COG0802	atpase or kinase
B7L45_RS08010	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B7L45_RS08020	COG1923	regulation of RNA biosynthetic process
B7L45_RS08025	COG0697	spore germination
B7L45_RS08040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7L45_RS08050	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7L45_RS08055	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7L45_RS08055	COG0519	Catalyzes the synthesis of GMP from XMP
B7L45_RS08060	COG4302	ethanolamine ammonia-lyase activity
B7L45_RS08065	COG4303	Ethanolamine ammonia lyase large subunit
B7L45_RS08070	COG0531	amino acid
B7L45_RS08090	COG1454	alcohol dehydrogenase
B7L45_RS08095	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7L45_RS08105	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B7L45_RS08125	COG0308	aminopeptidase N
B7L45_RS08135	COG4221	oxidoreductase activity
B7L45_RS08145	COG1605	Chorismate mutase
B7L45_RS08165	COG1309	transcriptional regulator
B7L45_RS08175	COG0668	transmembrane transport
B7L45_RS08210	COG4773	Receptor
B7L45_RS08225	COG0488	(ABC) transporter
B7L45_RS08230	COG0589	response to stress
B7L45_RS08245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7L45_RS08255	COG3135	benzoate transporter
B7L45_RS08260	COG1522	sequence-specific DNA binding
B7L45_RS08270	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7L45_RS08275	COG0583	DNA-binding transcription factor activity
B7L45_RS08285	COG0183	Belongs to the thiolase family
B7L45_RS08295	COG2030	dehydratase
B7L45_RS08300	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7L45_RS08315	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7L45_RS08325	COG0824	Thioesterase
B7L45_RS08330	COG1454	alcohol dehydrogenase
B7L45_RS08340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7L45_RS08360	COG0069	glutamate synthase activity
B7L45_RS08380	COG2814	Major facilitator Superfamily
B7L45_RS08395	COG0511	ligase activity, forming carbon-carbon bonds
B7L45_RS08410	COG1116	anion transmembrane transporter activity
B7L45_RS08410	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L45_RS08415	COG0745	RESPONSE REGULATOR receiver
B7L45_RS08425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L45_RS08425	COG2146	nitrite reductase [NAD(P)H] activity
B7L45_RS08430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L45_RS08435	COG0243	molybdopterin cofactor binding
B7L45_RS08445	COG0243	molybdopterin cofactor binding
B7L45_RS08450	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7L45_RS08465	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7L45_RS08465	COG0315	cyclic pyranopterin monophosphate synthase activity
B7L45_RS08470	COG0303	'Molybdopterin
B7L45_RS08480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L45_RS08485	COG0697	spore germination
B7L45_RS08505	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B7L45_RS08510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7L45_RS08570	COG2204	response regulator
B7L45_RS08575	COG3852	Histidine kinase
B7L45_RS08595	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7L45_RS08600	COG0575	Belongs to the CDS family
B7L45_RS08635	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7L45_RS08650	COG2137	regulation of response to DNA damage stimulus
B7L45_RS08660	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B7L45_RS08665	COG1011	Hydrolase
B7L45_RS08690	COG1522	sequence-specific DNA binding
B7L45_RS08700	COG1113	amino acid transport
B7L45_RS08715	COG0659	secondary active sulfate transmembrane transporter activity
B7L45_RS08720	COG2135	peptidase activity
B7L45_RS08735	COG3300	MHYT domain
B7L45_RS08735	COG5001	Diguanylate cyclase
B7L45_RS08755	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7L45_RS08755	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7L45_RS08755	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B7L45_RS08760	COG1105	Belongs to the carbohydrate kinase PfkB family
B7L45_RS08765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7L45_RS08765	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7L45_RS08795	COG0024	Methionine aminopeptidase
B7L45_RS08800	COG0583	DNA-binding transcription factor activity
B7L45_RS08810	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B7L45_RS08815	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7L45_RS08820	COG0516	GMP reductase activity
B7L45_RS08820	COG0517	IMP dehydrogenase activity
B7L45_RS08850	COG0552	protein localization to endoplasmic reticulum
B7L45_RS08860	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
B7L45_RS08875	COG4890	Cyd operon protein YbgT
B7L45_RS08880	COG1294	oxidase, subunit
B7L45_RS08900	COG1585	Membrane protein implicated in regulation of membrane protease activity
B7L45_RS08910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7L45_RS08915	COG4774	siderophore transport
B7L45_RS08930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7L45_RS08935	COG0569	domain protein
B7L45_RS08940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7L45_RS08970	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B7L45_RS08975	COG0542	response to heat
B7L45_RS09000	COG1902	pentaerythritol trinitrate reductase activity
B7L45_RS09000	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L45_RS09045	COG2323	membrane
B7L45_RS09050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B7L45_RS09060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7L45_RS09065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L45_RS09070	COG0183	Belongs to the thiolase family
B7L45_RS09075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7L45_RS09080	COG0596	Alpha beta hydrolase
B7L45_RS09085	COG2271	Major facilitator Superfamily
B7L45_RS09090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7L45_RS09095	COG3485	protocatechuate 3,4-dioxygenase
B7L45_RS09100	COG3485	protocatechuate 3,4-dioxygenase
B7L45_RS09105	COG0710	3-dehydroquinate dehydratase activity
B7L45_RS09110	COG3420	alginic acid biosynthetic process
B7L45_RS09115	COG3659	wide pore channel activity
B7L45_RS09120	COG4993	Dehydrogenase
B7L45_RS09130	COG2391	methyltransferase activity
B7L45_RS09145	COG1414	Transcriptional regulator
B7L45_RS09150	COG0583	DNA-binding transcription factor activity
B7L45_RS09155	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS09180	COG2814	Major facilitator Superfamily
B7L45_RS09190	COG0154	amidase activity
B7L45_RS09210	COG4638	Rieske (2fe-2S)
B7L45_RS09220	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS09230	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L45_RS09240	COG3733	amine oxidase
B7L45_RS09250	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS09260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7L45_RS09265	COG0183	Belongs to the thiolase family
B7L45_RS09270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L45_RS09275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7L45_RS09285	COG4829	muconolactone delta-isomerase
B7L45_RS09290	COG4948	Mandelate Racemase Muconate Lactonizing
B7L45_RS09295	COG0583	DNA-binding transcription factor activity
B7L45_RS09305	COG2186	Transcriptional regulator
B7L45_RS09325	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS09345	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS09350	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS09355	COG3829	transcription factor binding
B7L45_RS09365	COG3162	membrane
B7L45_RS09380	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS09395	COG0753	catalase activity
B7L45_RS09420	COG1846	Transcriptional regulator
B7L45_RS09425	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L45_RS09425	COG1902	pentaerythritol trinitrate reductase activity
B7L45_RS09435	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7L45_RS09465	COG1309	transcriptional regulator
B7L45_RS09475	COG1335	isochorismatase
B7L45_RS09480	COG0583	DNA-binding transcription factor activity
B7L45_RS09490	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7L45_RS09490	COG0475	glutathione-regulated potassium exporter activity
B7L45_RS09500	COG1473	amidohydrolase
B7L45_RS09515	COG2831	hemolysin activation secretion protein
B7L45_RS09520	COG3210	domain, Protein
B7L45_RS09545	COG2188	Transcriptional regulator
B7L45_RS09560	COG0583	DNA-binding transcription factor activity
B7L45_RS09590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B7L45_RS09610	COG1566	PFAM secretion protein HlyD family protein
B7L45_RS09625	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS09630	COG0129	dihydroxy-acid dehydratase activity
B7L45_RS09640	COG0583	DNA-binding transcription factor activity
B7L45_RS09645	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7L45_RS09655	COG2084	Dehydrogenase
B7L45_RS09660	COG2207	Transcriptional regulator
B7L45_RS09675	COG1064	alcohol dehydrogenase
B7L45_RS09685	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7L45_RS09690	COG1120	ATPase activity
B7L45_RS09710	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7L45_RS09830	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B7L45_RS09880	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS09895	COG2207	Transcriptional regulator
B7L45_RS09905	COG2205	protein histidine kinase activity
B7L45_RS09910	COG0745	RESPONSE REGULATOR receiver
B7L45_RS09915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L45_RS09920	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7L45_RS09925	COG1538	Outer membrane efflux protein
B7L45_RS09935	COG2072	flavoprotein involved in K transport
B7L45_RS09955	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7L45_RS09975	COG3539	Fimbrial protein
B7L45_RS10005	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B7L45_RS10015	COG0753	catalase activity
B7L45_RS10030	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7L45_RS10090	COG3433	isochorismatase activity
B7L45_RS10090	COG1535	isochorismatase
B7L45_RS10095	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS10100	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B7L45_RS10105	COG4149	molybdate abc transporter
B7L45_RS10110	COG0725	ABC transporter, periplasmic molybdate-binding protein
B7L45_RS10120	COG4638	Rieske (2fe-2S)
B7L45_RS10125	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B7L45_RS10130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L45_RS10130	COG0543	2 iron, 2 sulfur cluster binding
B7L45_RS10155	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS10170	COG2207	Transcriptional regulator
B7L45_RS10180	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS10185	COG2610	gluconate transmembrane transporter activity
B7L45_RS10195	COG0583	DNA-binding transcription factor activity
B7L45_RS10205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L45_RS10210	COG2031	fatty acid transporter
B7L45_RS10215	COG0183	Belongs to the thiolase family
B7L45_RS10220	COG0583	DNA-binding transcription factor activity
B7L45_RS10225	COG0583	DNA-binding transcription factor activity
B7L45_RS10240	COG1027	Aspartate ammonia-lyase
B7L45_RS10250	COG0477	Major facilitator Superfamily
B7L45_RS10270	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L45_RS10275	COG4521	taurine ABC transporter
B7L45_RS10290	COG2188	Transcriptional regulator
B7L45_RS10300	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B7L45_RS10305	COG1733	regulation of RNA biosynthetic process
B7L45_RS10310	COG3708	Transcriptional regulator
B7L45_RS10310	COG2207	Transcriptional regulator
B7L45_RS10325	COG0730	response to heat
B7L45_RS10335	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L45_RS10335	COG3453	Protein conserved in bacteria
B7L45_RS10345	COG3781	membrane
B7L45_RS10350	COG1063	alcohol dehydrogenase
B7L45_RS10360	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7L45_RS10365	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7L45_RS10370	COG0022	dehydrogenase e1 component
B7L45_RS10375	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7L45_RS10380	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7L45_RS10395	COG3706	GGDEF domain
B7L45_RS10410	COG0133	tryptophan synthase activity
B7L45_RS10420	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7L45_RS10455	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B7L45_RS10480	COG2226	methyltransferase
B7L45_RS10535	COG0842	Transport permease protein
B7L45_RS10540	COG0842	Transport permease protein
B7L45_RS10545	COG1131	(ABC) transporter
B7L45_RS10560	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7L45_RS10565	COG4773	Receptor
B7L45_RS10585	COG0730	response to heat
B7L45_RS10590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7L45_RS10610	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B7L45_RS10665	COG4264	IucA IucC family
B7L45_RS10670	COG4264	IucA IucC family
B7L45_RS10690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7L45_RS10705	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS10710	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS10715	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7L45_RS10720	COG2207	Transcriptional regulator
B7L45_RS10725	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7L45_RS10730	COG0776	regulation of translation
B7L45_RS10755	COG0822	iron-sulfur transferase activity
B7L45_RS10760	COG0316	Belongs to the HesB IscA family
B7L45_RS10790	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B7L45_RS10810	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B7L45_RS10815	COG0702	epimerase
B7L45_RS10850	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7L45_RS10860	COG0339	signal peptide processing
B7L45_RS10905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B7L45_RS10910	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B7L45_RS10940	COG0776	regulation of translation
B7L45_RS11005	COG0084	hydrolase, TatD family'
B7L45_RS11025	COG1663	tetraacyldisaccharide 4'-kinase activity
B7L45_RS11030	COG1132	(ABC) transporter
B7L45_RS11040	COG0811	peptide transport
B7L45_RS11045	COG1475	DNA binding
B7L45_RS11050	COG1192	Involved in chromosome partitioning
B7L45_RS11060	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7L45_RS11075	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7L45_RS11080	COG0191	fructose-bisphosphate aldolase activity
B7L45_RS11100	COG0424	maF-like protein
B7L45_RS11105	COG2850	peptidyl-arginine hydroxylation
B7L45_RS11115	COG0640	Transcriptional regulator
B7L45_RS11125	COG3619	membrane
B7L45_RS11130	COG3122	Protein conserved in bacteria
B7L45_RS11135	COG1132	(ABC) transporter
B7L45_RS11155	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B7L45_RS11160	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7L45_RS11170	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7L45_RS11170	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7L45_RS11170	COG0506	proline dehydrogenase activity
B7L45_RS11175	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B7L45_RS11190	COG3698	Phosphodiester glycosidase
B7L45_RS11200	COG2353	YceI-like domain
B7L45_RS11210	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7L45_RS11255	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B7L45_RS11255	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B7L45_RS11280	COG3539	Fimbrial protein
B7L45_RS11285	COG3121	Chaperone
B7L45_RS11315	COG0697	spore germination
B7L45_RS11325	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B7L45_RS11335	COG0583	DNA-binding transcription factor activity
B7L45_RS11355	COG1309	transcriptional regulator
B7L45_RS11375	COG1522	sequence-specific DNA binding
B7L45_RS11385	COG1126	abc transporter atp-binding protein
B7L45_RS11390	COG0765	amino acid transport
B7L45_RS11395	COG0765	amino acid transport
B7L45_RS11425	COG1464	Belongs to the NlpA lipoprotein family
B7L45_RS11435	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7L45_RS11440	COG2011	ABC-type metal ion transport system permease component
B7L45_RS11445	COG0012	GTP binding
B7L45_RS11470	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7L45_RS11510	COG0386	Belongs to the glutathione peroxidase family
B7L45_RS11520	COG0436	Aminotransferase
B7L45_RS11560	COG3634	alkyl hydroperoxide reductase activity
B7L45_RS11575	COG0583	DNA-binding transcription factor activity
B7L45_RS11580	COG0798	PFAM Bile acid sodium symporter
B7L45_RS11585	COG0640	Transcriptional regulator
B7L45_RS11600	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B7L45_RS11610	COG0583	DNA-binding transcription factor activity
B7L45_RS11620	COG1953	Uracil, thiamine, allantoin
B7L45_RS11630	COG2175	clavaminate synthase activity
B7L45_RS11635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L45_RS11640	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B7L45_RS11645	COG4521	taurine ABC transporter
B7L45_RS11655	COG0477	Major facilitator Superfamily
B7L45_RS11680	COG1271	oxidase subunit
B7L45_RS11685	COG1294	oxidase, subunit
B7L45_RS11690	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L45_RS11710	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B7L45_RS11730	COG3052	prosthetic group binding
B7L45_RS11735	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
B7L45_RS11745	COG2814	Major facilitator Superfamily
B7L45_RS11765	COG1346	cytolysis
B7L45_RS11775	COG0583	DNA-binding transcription factor activity
B7L45_RS11780	COG0625	glutathione transferase activity
B7L45_RS11785	COG0625	glutathione transferase activity
B7L45_RS11790	COG0583	DNA-binding transcription factor activity
B7L45_RS11805	COG1045	serine acetyltransferase
B7L45_RS11810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7L45_RS11815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7L45_RS11820	COG1280	lysine exporter protein (LysE YggA)
B7L45_RS11830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7L45_RS11835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7L45_RS11840	COG1126	abc transporter atp-binding protein
B7L45_RS11845	COG0765	amino acid transport
B7L45_RS11850	COG0765	amino acid transport
B7L45_RS11865	COG0784	Response regulator, receiver
B7L45_RS11865	COG2205	protein histidine kinase activity
B7L45_RS11885	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B7L45_RS11905	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS11950	COG0583	DNA-binding transcription factor activity
B7L45_RS11970	COG0318	PFAM AMP-dependent synthetase and ligase
B7L45_RS11975	COG1309	transcriptional regulator
B7L45_RS11980	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS11985	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7L45_RS11990	COG1024	Enoyl-CoA hydratase
B7L45_RS11995	COG4770	biotin carboxylase activity
B7L45_RS12005	COG0583	DNA-binding transcription factor activity
B7L45_RS12020	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS12030	COG2814	Major facilitator Superfamily
B7L45_RS12040	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L45_RS12045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7L45_RS12050	COG2814	Major facilitator Superfamily
B7L45_RS12055	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS12060	COG1024	Enoyl-CoA hydratase
B7L45_RS12065	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS12070	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7L45_RS12075	COG0183	Belongs to the thiolase family
B7L45_RS12085	COG2814	Major facilitator Superfamily
B7L45_RS12095	COG1024	Enoyl-CoA hydratase
B7L45_RS12110	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS12115	COG2814	Major facilitator Superfamily
B7L45_RS12120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7L45_RS12125	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B7L45_RS12140	COG3842	ATPase activity
B7L45_RS12145	COG1840	ABC-type Fe3 transport system, periplasmic component
B7L45_RS12155	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L45_RS12160	COG1414	Transcriptional regulator
B7L45_RS12170	COG0583	DNA-binding transcription factor activity
B7L45_RS12175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7L45_RS12180	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS12190	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B7L45_RS12195	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS12200	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7L45_RS12225	COG3038	cytochrome b561
B7L45_RS12230	COG0753	catalase activity
B7L45_RS12270	COG2050	protein possibly involved in aromatic compounds catabolism
B7L45_RS12280	COG3327	negative regulation of DNA-templated transcription, initiation
B7L45_RS12285	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
B7L45_RS12290	COG0183	Belongs to the thiolase family
B7L45_RS12295	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7L45_RS12300	COG1024	Enoyl-CoA hydratase
B7L45_RS12305	COG1024	Enoyl-CoA hydratase
B7L45_RS12310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L45_RS12315	COG2151	metal-sulfur cluster biosynthetic enzyme
B7L45_RS12320	COG3396	Phenylacetate-CoA oxygenase
B7L45_RS12325	COG3460	Phenylacetate-CoA oxygenase
B7L45_RS12330	COG3396	Phenylacetate-CoA oxygenase
B7L45_RS12335	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS12335	COG2030	dehydratase
B7L45_RS12340	COG1760	l-serine dehydratase
B7L45_RS12345	COG0531	amino acid
B7L45_RS12350	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS12365	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L45_RS12375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7L45_RS12395	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L45_RS12410	COG0789	Transcriptional regulator
B7L45_RS12435	COG1116	anion transmembrane transporter activity
B7L45_RS12440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7L45_RS12450	COG0864	Transcriptional regulator
B7L45_RS12465	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L45_RS12470	COG0439	Biotin carboxylase
B7L45_RS12485	COG1063	alcohol dehydrogenase
B7L45_RS12495	COG1309	transcriptional regulator
B7L45_RS12525	COG0038	chloride channel
B7L45_RS12530	COG4770	biotin carboxylase activity
B7L45_RS12550	COG1914	H( )-stimulated, divalent metal cation uptake system
B7L45_RS12555	COG0583	DNA-binding transcription factor activity
B7L45_RS12610	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7L45_RS12630	COG2814	Major facilitator Superfamily
B7L45_RS12645	COG1560	Kdo2-lipid A biosynthetic process
B7L45_RS12655	COG5006	permease, DMT superfamily
B7L45_RS12660	COG1522	sequence-specific DNA binding
B7L45_RS12675	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B7L45_RS12685	COG4122	O-methyltransferase activity
B7L45_RS12715	COG1538	Outer membrane efflux protein
B7L45_RS12720	COG1137	ATPase activity
B7L45_RS12725	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B7L45_RS12735	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B7L45_RS12740	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B7L45_RS12740	COG0517	IMP dehydrogenase activity
B7L45_RS12780	COG2814	Major facilitator Superfamily
B7L45_RS12815	COG1278	Cold shock
B7L45_RS12820	COG1280	lysine exporter protein (LysE YggA)
B7L45_RS12855	COG1570	exodeoxyribonuclease VII activity
B7L45_RS12910	COG0583	DNA-binding transcription factor activity
B7L45_RS12915	COG4638	Rieske (2fe-2S)
B7L45_RS12920	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B7L45_RS12925	COG0543	2 iron, 2 sulfur cluster binding
B7L45_RS12925	COG0633	Ferredoxin
B7L45_RS12930	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS12935	COG3135	benzoate transporter
B7L45_RS12940	COG2814	Major facilitator Superfamily
B7L45_RS12955	COG1643	Atp-dependent helicase
B7L45_RS12960	COG0450	alkyl hydroperoxide reductase
B7L45_RS12970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7L45_RS12980	COG3634	alkyl hydroperoxide reductase activity
B7L45_RS13000	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B7L45_RS13005	COG0625	glutathione transferase activity
B7L45_RS13015	COG2885	chlorophyll binding
B7L45_RS13050	COG0542	response to heat
B7L45_RS13065	COG1765	OsmC-like protein
B7L45_RS13080	COG0667	Aldo Keto reductase
B7L45_RS13095	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B7L45_RS13105	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7L45_RS13115	COG0527	aspartate kinase activity
B7L45_RS13125	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7L45_RS13135	COG3038	cytochrome b561
B7L45_RS13140	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7L45_RS13145	COG2252	PERMEase
B7L45_RS13155	COG2072	flavoprotein involved in K transport
B7L45_RS13170	COG1741	Belongs to the pirin family
B7L45_RS13175	COG1309	transcriptional regulator
B7L45_RS13185	COG0300	oxidoreductase activity
B7L45_RS13190	COG2072	flavoprotein involved in K transport
B7L45_RS13205	COG3209	COG3209 Rhs family protein
B7L45_RS13235	COG4269	membrane
B7L45_RS13250	COG1902	pentaerythritol trinitrate reductase activity
B7L45_RS13250	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L45_RS13260	COG2203	Gaf domain
B7L45_RS13260	COG3706	GGDEF domain
B7L45_RS13260	COG4251	negative regulation of phosphorylation
B7L45_RS13260	COG5001	Diguanylate cyclase
B7L45_RS13270	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L45_RS13290	COG4172	Belongs to the ABC transporter superfamily
B7L45_RS13295	COG4239	(ABC) transporter, permease
B7L45_RS13300	COG4174	ABC transporter (Permease)
B7L45_RS13310	COG1388	LysM domain
B7L45_RS13310	COG0741	lytic transglycosylase activity
B7L45_RS13310	COG1388	LysM domain
B7L45_RS13310	COG0741	lytic transglycosylase activity
B7L45_RS13315	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L45_RS13355	COG0583	DNA-binding transcription factor activity
B7L45_RS13360	COG1279	arginine transmembrane transporter activity
B7L45_RS13380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L45_RS13385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L45_RS13390	COG0006	proline dipeptidase activity
B7L45_RS13425	COG2194	sulfuric ester hydrolase activity
B7L45_RS13470	COG0739	heme binding
B7L45_RS13795	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B7L45_RS13820	COG3384	dioxygenase
B7L45_RS13830	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7L45_RS13835	COG2878	Part of a membrane complex involved in electron transport
B7L45_RS13840	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7L45_RS13860	COG0768	penicillin binding
B7L45_RS13865	COG0742	ribosomal rna small subunit methyltransferase
B7L45_RS13880	COG0830	nickel cation binding
B7L45_RS13890	COG0804	urea catabolic process
B7L45_RS13895	COG0804	urea catabolic process
B7L45_RS13935	COG1253	flavin adenine dinucleotide binding
B7L45_RS13945	COG2851	Citrate transporter
B7L45_RS13990	COG1773	rubredoxin
B7L45_RS13995	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L45_RS14005	COG0583	DNA-binding transcription factor activity
B7L45_RS14030	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B7L45_RS14035	COG4181	ATPase activity
B7L45_RS14080	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B7L45_RS14095	COG0306	phosphate transporter
B7L45_RS14105	COG3958	Transketolase
B7L45_RS14110	COG3959	Transketolase, thiamine diphosphate binding domain
B7L45_RS14115	COG2271	Major facilitator Superfamily
B7L45_RS14120	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS14125	COG0583	DNA-binding transcription factor activity
B7L45_RS14145	COG2223	nitrite transmembrane transporter activity
B7L45_RS14150	COG2207	Transcriptional regulator
B7L45_RS14155	COG2066	Belongs to the glutaminase family
B7L45_RS14160	COG0242	peptide deformylase activity
B7L45_RS14165	COG0477	Major facilitator Superfamily
B7L45_RS14175	COG0028	Belongs to the TPP enzyme family
B7L45_RS14190	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS14195	COG2267	carboxylic ester hydrolase activity
B7L45_RS14205	COG2271	Major facilitator Superfamily
B7L45_RS14210	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L45_RS14220	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS14240	COG1414	Transcriptional regulator
B7L45_RS14255	COG1024	Enoyl-CoA hydratase
B7L45_RS14265	COG1215	transferase activity, transferring glycosyl groups
B7L45_RS14270	COG0726	polysaccharide deacetylase
B7L45_RS14270	COG1649	PFAM Uncharacterised BCR, COG1649
B7L45_RS14280	COG4681	YaeQ
B7L45_RS14290	COG0523	cobalamin synthesis protein
B7L45_RS14300	COG1607	acyl-coa hydrolase
B7L45_RS14310	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L45_RS14315	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L45_RS14320	COG1309	transcriptional regulator
B7L45_RS14345	COG2040	homocysteine
B7L45_RS14350	COG0531	amino acid
B7L45_RS14405	COG1595	DNA-templated transcription, initiation
B7L45_RS14415	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L45_RS14420	COG0477	Major facilitator Superfamily
B7L45_RS14560	COG0592	DNA-directed DNA polymerase activity
B7L45_RS14600	COG2026	Addiction module toxin, RelE StbE family
B7L45_RS14800	COG1484	DNA-dependent DNA replication
B7L45_RS14910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L45_RS14940	COG0405	Gamma-glutamyltransferase
B7L45_RS14945	COG2814	Major facilitator Superfamily
B7L45_RS14955	COG2050	protein possibly involved in aromatic compounds catabolism
B7L45_RS14970	COG1090	epimerase
B7L45_RS14990	COG0420	3'-5' exonuclease activity
B7L45_RS15015	COG0735	belongs to the Fur family
B7L45_RS15020	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7L45_RS15045	COG0121	glutamine amidotransferase
B7L45_RS15060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7L45_RS15070	COG0210	DNA helicase
B7L45_RS15075	COG2885	chlorophyll binding
B7L45_RS15080	COG0204	Acyl-transferase
B7L45_RS15095	COG2894	cell division
B7L45_RS15115	COG1280	lysine exporter protein (LysE YggA)
B7L45_RS15120	COG1674	ftsk spoiiie
B7L45_RS15120	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B7L45_RS15125	COG0492	ferredoxin-NADP+ reductase activity
B7L45_RS15130	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B7L45_RS15140	COG0456	acetyltransferase
B7L45_RS15185	COG1981	membrane
B7L45_RS15200	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B7L45_RS15200	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7L45_RS15220	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS15230	COG0657	acetylesterase activity
B7L45_RS15240	COG0473	3-isopropylmalate dehydrogenase activity
B7L45_RS15245	COG0583	DNA-binding transcription factor activity
B7L45_RS15265	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7L45_RS15290	COG0564	pseudouridine synthase activity
B7L45_RS15300	COG0358	DNA primase activity
B7L45_RS15315	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B7L45_RS15345	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7L45_RS15375	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7L45_RS15385	COG0352	thiamine-phosphate diphosphorylase activity
B7L45_RS15385	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B7L45_RS15385	COG0351	phosphomethylpyrimidine kinase
B7L45_RS15390	COG1652	LysM domain
B7L45_RS15415	COG1399	metal-binding, possibly nucleic acid-binding protein
B7L45_RS15420	COG3101	peptidyl-lysine hydroxylation
B7L45_RS15425	COG0009	L-threonylcarbamoyladenylate synthase
B7L45_RS15430	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B7L45_RS15435	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B7L45_RS15450	COG4106	trans-aconitate 2-methyltransferase activity
B7L45_RS15465	COG0596	Alpha beta hydrolase
B7L45_RS15465	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7L45_RS15465	COG2226	methyltransferase
B7L45_RS15470	COG1877	trehalose-phosphatase activity
B7L45_RS15475	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
B7L45_RS15480	COG2223	nitrite transmembrane transporter activity
B7L45_RS15500	COG1196	nuclear chromosome segregation
B7L45_RS15510	COG0730	response to heat
B7L45_RS15525	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B7L45_RS15535	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7L45_RS15590	COG0489	protein tyrosine kinase activity
B7L45_RS15600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7L45_RS15600	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7L45_RS15630	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B7L45_RS15635	COG2081	HI0933 family
B7L45_RS15640	COG0668	transmembrane transport
B7L45_RS15660	COG0583	DNA-binding transcription factor activity
B7L45_RS15680	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7L45_RS15685	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7L45_RS15715	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B7L45_RS15755	COG0745	RESPONSE REGULATOR receiver
B7L45_RS15775	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7L45_RS15785	COG2205	protein histidine kinase activity
B7L45_RS15855	COG4993	Dehydrogenase
B7L45_RS15875	COG0384	phenazine biosynthesis protein PhzF
B7L45_RS15905	COG1061	Type III restriction enzyme res subunit
B7L45_RS15915	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7L45_RS15920	COG1192	Involved in chromosome partitioning
B7L45_RS15930	COG1061	Type III restriction enzyme res subunit
B7L45_RS15955	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L45_RS15970	COG0583	DNA-binding transcription factor activity
B7L45_RS16000	COG0583	DNA-binding transcription factor activity
B7L45_RS16020	COG0583	DNA-binding transcription factor activity
B7L45_RS16025	COG1053	succinate dehydrogenase
B7L45_RS16035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7L45_RS16040	COG2814	Major facilitator Superfamily
B7L45_RS16045	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS16050	COG0583	DNA-binding transcription factor activity
B7L45_RS16055	COG1063	alcohol dehydrogenase
B7L45_RS16085	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B7L45_RS16090	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B7L45_RS16095	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7L45_RS16110	COG3667	copper resistance
B7L45_RS16115	COG2132	Multicopper oxidase
B7L45_RS16125	COG0561	phosphatase activity
B7L45_RS16130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7L45_RS16155	COG1214	PFAM Peptidase M22, glycoprotease
B7L45_RS16205	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7L45_RS16215	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B7L45_RS16220	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B7L45_RS16225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7L45_RS16285	COG1061	Type III restriction enzyme res subunit
B7L45_RS16295	COG1192	Involved in chromosome partitioning
B7L45_RS16300	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7L45_RS16310	COG1061	Type III restriction enzyme res subunit
B7L45_RS16335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7L45_RS16345	COG1846	Transcriptional regulator
B7L45_RS16350	COG1764	response to oxidative stress
B7L45_RS16390	COG0037	tRNA processing
B7L45_RS16400	COG0248	Ppx GppA phosphatase
B7L45_RS16425	COG0072	phenylalanine-tRNA ligase activity
B7L45_RS16470	COG1238	metal cluster binding
B7L45_RS16475	COG0625	glutathione transferase activity
B7L45_RS16495	COG0318	PFAM AMP-dependent synthetase and ligase
B7L45_RS16500	COG3028	Belongs to the UPF0307 family
B7L45_RS16505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7L45_RS16525	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B7L45_RS16530	COG0617	tRNA 3'-terminal CCA addition
B7L45_RS16535	COG1555	photosystem II stabilization
B7L45_RS16540	COG3956	TIGRFAM MazG family protein
B7L45_RS16550	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7L45_RS16570	COG5002	protein histidine kinase activity
B7L45_RS16570	COG0784	Response regulator, receiver
B7L45_RS16570	COG2205	protein histidine kinase activity
B7L45_RS16575	COG1024	Enoyl-CoA hydratase
B7L45_RS16580	COG2084	Dehydrogenase
B7L45_RS16585	COG3622	Belongs to the hyi family
B7L45_RS16615	COG0697	spore germination
B7L45_RS16625	COG2814	Major facilitator Superfamily
B7L45_RS16630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7L45_RS16640	COG0583	DNA-binding transcription factor activity
B7L45_RS16645	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B7L45_RS16660	COG0084	hydrolase, TatD family'
B7L45_RS16675	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B7L45_RS16710	COG0440	acetolactate synthase activity
B7L45_RS16715	COG0028	Belongs to the TPP enzyme family
B7L45_RS16745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L45_RS16750	COG0577	efflux transmembrane transporter activity
B7L45_RS16750	COG1136	(ABC) transporter
B7L45_RS16755	COG1538	Outer membrane efflux protein
B7L45_RS16770	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B7L45_RS16775	COG1162	GTPase activity
B7L45_RS16785	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7L45_RS16805	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7L45_RS16810	COG1028	Short-chain dehydrogenase reductase Sdr
B7L45_RS16850	COG2986	histidine ammonia-lyase
B7L45_RS16865	COG0318	PFAM AMP-dependent synthetase and ligase
B7L45_RS16875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7L45_RS16920	COG1426	Protein conserved in bacteria
B7L45_RS16955	COG0793	Belongs to the peptidase S41A family
B7L45_RS16970	COG2267	carboxylic ester hydrolase activity
B7L45_RS16980	COG1012	belongs to the aldehyde dehydrogenase family
B7L45_RS16985	COG3265	gluconokinase activity
B7L45_RS16995	COG0800	Aldolase
B7L45_RS17005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7L45_RS17010	COG0280	phosphate acetyltransferase
B7L45_RS17010	COG0857	belongs to the CobB CobQ family
B7L45_RS17015	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7L45_RS17015	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B7L45_RS17035	COG0740	serine-type endopeptidase activity
B7L45_RS17045	COG4774	siderophore transport
B7L45_RS17055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7L45_RS17065	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7L45_RS17065	COG2813	Specifically methylates the guanine in position
B7L45_RS17165	COG0788	formyltetrahydrofolate deformylase activity
B7L45_RS17190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7L45_RS17190	COG4651	solute:proton antiporter activity
B7L45_RS17210	COG0724	RNA recognition motif
B7L45_RS17215	COG0210	DNA helicase
B7L45_RS17240	COG1733	regulation of RNA biosynthetic process
B7L45_RS17250	COG2900	Belongs to the SlyX family
B7L45_RS17255	COG0488	(ABC) transporter
B7L45_RS17260	COG1280	lysine exporter protein (LysE YggA)
B7L45_RS17265	COG1560	Kdo2-lipid A biosynthetic process
B7L45_RS17275	COG1301	dicarboxylic acid transport
B7L45_RS17330	COG0473	3-isopropylmalate dehydrogenase activity
B7L45_RS17395	COG0583	DNA-binding transcription factor activity
B7L45_RS17405	COG0625	glutathione transferase activity
B7L45_RS17410	COG2378	regulation of single-species biofilm formation
B7L45_RS17415	COG0546	phosphoglycolate phosphatase activity
B7L45_RS17430	COG1530	ribonuclease E activity
B7L45_RS17435	COG0318	PFAM AMP-dependent synthetase and ligase
B7L45_RS17450	COG0583	DNA-binding transcription factor activity
B7L45_RS17455	COG4221	oxidoreductase activity
B7L45_RS17460	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7L45_RS17470	COG0534	Mate efflux family protein
B7L45_RS17485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B7L45_RS17520	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B7L45_RS17525	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L45_RS17540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7L45_RS17550	COG0644	oxidoreductase
B7L45_RS17550	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B7L45_RS17555	COG0425	Belongs to the sulfur carrier protein TusA family
B7L45_RS17560	COG4535	Mg2 and Co2 transporter CorC
B7L45_RS17570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7L45_RS17595	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7L45_RS17600	COG0475	glutathione-regulated potassium exporter activity
B7L45_RS17600	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7L45_RS17605	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B7L45_RS17615	COG0484	heat shock protein binding
B7L45_RS17620	COG0789	Transcriptional regulator
B7L45_RS17625	COG0598	Magnesium transport protein CorA
B7L45_RS17640	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7L45_RS17645	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7L45_RS17650	COG1074	ATP-dependent DNA helicase activity
B7L45_RS17655	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B7L45_RS17675	COG2226	methyltransferase
B7L45_RS17690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L45_RS17695	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B7L45_RS17710	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7L45_RS17710	COG2111	Na H antiporter
B7L45_RS17715	COG1006	Multisubunit Na H antiporter MnhC subunit
B7L45_RS17720	COG0651	ATP synthesis coupled electron transport
B7L45_RS17725	COG1863	multisubunit Na H antiporter MnhE subunit
B7L45_RS17730	COG2212	antiporter activity
B7L45_RS17735	COG1320	monovalent cation:proton antiporter activity
B7L45_RS17750	COG0195	Participates in both transcription termination and antitermination
B7L45_RS17800	COG0237	dephospho-CoA kinase activity
B7L45_RS17810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7L45_RS17825	COG0497	DNA recombination
B7L45_RS17835	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B7L45_RS17865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7L45_RS17865	COG2169	Transcriptional regulator
B7L45_RS17870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7L45_RS17935	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7L45_RS17950	COG0326	Molecular chaperone. Has ATPase activity
B7L45_RS17965	COG2056	Na+-H+ antiporter family
B7L45_RS17970	COG0596	Alpha beta hydrolase
B7L45_RS18065	COG0546	phosphoglycolate phosphatase activity
B7L45_RS18070	COG1716	ATPase activity
B7L45_RS18115	COG0181	hydroxymethylbilane synthase activity
B7L45_RS18125	COG3275	phosphorelay sensor kinase activity
B7L45_RS18145	COG1538	Outer membrane efflux protein
B7L45_RS18150	COG0697	spore germination
B7L45_RS18175	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7L45_RS18180	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7L45_RS18185	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7L45_RS18190	COG0772	Belongs to the SEDS family
B7L45_RS18215	COG4974	Belongs to the 'phage' integrase family
B7L45_RS18220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L45_RS18230	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7L45_RS18240	COG2197	response regulator
B7L45_RS18255	COG0793	Belongs to the peptidase S41A family
B7L45_RS18260	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B7L45_RS18265	COG0795	lipopolysaccharide-transporting ATPase activity
B7L45_RS18305	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7L45_RS18305	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7L45_RS18315	COG0004	ammonium transporteR
B7L45_RS18320	COG0347	Belongs to the P(II) protein family
B7L45_RS18330	COG0606	chelatase, subunit chli
B7L45_RS18340	COG0659	secondary active sulfate transmembrane transporter activity
B7L45_RS18345	COG0589	response to stress
B7L45_RS18375	COG0606	chelatase, subunit chli
B7L45_RS18380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L45_RS18390	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L45_RS18405	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B7L45_RS18420	COG0318	PFAM AMP-dependent synthetase and ligase
B7L45_RS18430	COG0477	Major facilitator Superfamily
B7L45_RS18435	COG2860	membrane
B7L45_RS18445	COG1253	flavin adenine dinucleotide binding
B7L45_RS18465	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7L45_RS18500	COG0655	NAD(P)H dehydrogenase (quinone) activity
B7L45_RS18510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7L45_RS18545	COG1309	transcriptional regulator
B7L45_RS18580	COG0758	DNA mediated transformation
B7L45_RS18590	COG0697	spore germination
B7L45_RS18595	COG1309	transcriptional regulator
B7L45_RS18610	COG0386	Belongs to the glutathione peroxidase family
B7L45_RS18675	COG1121	(ABC) transporter
B7L45_RS18680	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7L45_RS18685	COG1280	lysine exporter protein (LysE YggA)
B7L45_RS18690	COG2837	iron assimilation
B7L45_RS18695	COG0281	malic enzyme
B7L45_RS18740	COG0519	Catalyzes the synthesis of GMP from XMP
B7L45_RS18740	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7L45_RS18745	COG4399	Belongs to the UPF0754 family
B7L45_RS18750	COG2259	Doxx family
B7L45_RS18755	COG0586	Pfam SNARE associated Golgi protein
B7L45_RS18770	COG1192	Involved in chromosome partitioning
B7L45_RS18780	COG0271	Belongs to the BolA IbaG family
B7L45_RS18820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7L45_RS18820	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B7L45_RS18820	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B7L45_RS18820	COG3321	synthase
B7L45_RS18825	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS18840	COG2197	response regulator
B7L45_RS18850	COG3916	Acyl-homoserine-lactone synthase
B7L45_RS18855	COG0477	Major facilitator Superfamily
B7L45_RS18860	COG1024	Enoyl-CoA hydratase
B7L45_RS18865	COG1024	Enoyl-CoA hydratase
B7L45_RS18870	COG1960	acyl-CoA dehydrogenase activity
B7L45_RS18875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7L45_RS18895	COG1113	amino acid transport
B7L45_RS18900	COG1113	amino acid transport
B7L45_RS18905	COG0251	oxidation-reduction process
B7L45_RS18945	COG0564	pseudouridine synthase activity
B7L45_RS19020	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7L45_RS19035	COG1802	Transcriptional regulator
B7L45_RS19040	COG1448	Aminotransferase
B7L45_RS19045	COG0277	FAD linked oxidase domain protein
B7L45_RS19055	COG2186	Transcriptional regulator
B7L45_RS19065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7L45_RS19070	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7L45_RS19085	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7L45_RS19090	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7L45_RS19095	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan