locus-tag	class	description
FDM99_RS00030	COG1607	acyl-coa hydrolase
FDM99_RS00090	COG2199	diguanylate cyclase activity
FDM99_RS00100	COG1408	metallophosphoesterase
FDM99_RS00105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDM99_RS00115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FDM99_RS00135	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDM99_RS00140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDM99_RS00145	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
FDM99_RS00155	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FDM99_RS00160	COG0625	glutathione transferase activity
FDM99_RS00165	COG2969	positive regulation of protein catabolic process
FDM99_RS00185	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS00190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDM99_RS00205	COG1309	transcriptional regulator
FDM99_RS00210	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS00255	COG1183	phosphatidylcholine synthase activity
FDM99_RS00260	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FDM99_RS00290	COG0739	heme binding
FDM99_RS00290	COG1196	nuclear chromosome segregation
FDM99_RS00290	COG0741	lytic transglycosylase activity
FDM99_RS00300	COG1702	phosphate starvation-inducible protein PhoH
FDM99_RS00335	COG1295	ribonuclease BN
FDM99_RS00340	COG0697	spore germination
FDM99_RS00345	COG2169	Transcriptional regulator
FDM99_RS00350	COG0179	Fumarylacetoacetate (FAA) hydrolase
FDM99_RS00400	COG0339	signal peptide processing
FDM99_RS00405	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FDM99_RS00435	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FDM99_RS00440	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS00595	COG0626	cystathionine gamma-synthase activity
FDM99_RS00600	COG0433	COG0433 Predicted ATPase
FDM99_RS00605	COG1017	nitric oxide dioxygenase activity
FDM99_RS00605	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDM99_RS00610	COG1959	2 iron, 2 sulfur cluster binding
FDM99_RS00625	COG1301	dicarboxylic acid transport
FDM99_RS00630	COG1946	Acyl-CoA thioesterase
FDM99_RS00650	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FDM99_RS00655	COG1040	competence protein
FDM99_RS00660	COG0494	nUDIX hydrolase
FDM99_RS00670	COG0598	Magnesium transport protein CorA
FDM99_RS00680	COG2854	intermembrane phospholipid transfer
FDM99_RS00690	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDM99_RS00695	COG1127	ABC transporter
FDM99_RS00705	COG0513	Belongs to the DEAD box helicase family
FDM99_RS00725	COG0408	coproporphyrinogen oxidase activity
FDM99_RS00740	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS00750	COG1983	PspC domain protein
FDM99_RS00755	COG0517	IMP dehydrogenase activity
FDM99_RS00810	COG0583	DNA-binding transcription factor activity
FDM99_RS00850	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS00860	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDM99_RS00865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDM99_RS00870	COG0833	amino acid
FDM99_RS00900	COG1192	Involved in chromosome partitioning
FDM99_RS00905	COG0628	permease
FDM99_RS00915	COG1289	transmembrane transporter activity
FDM99_RS00930	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDM99_RS00935	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FDM99_RS00950	COG0277	FAD linked oxidase domain protein
FDM99_RS00955	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDM99_RS00980	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDM99_RS00985	COG5380	lipid catabolic process
FDM99_RS01005	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDM99_RS01060	COG0194	GDP metabolic process
FDM99_RS01075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDM99_RS01095	COG3307	-O-antigen
FDM99_RS01105	COG4969	Belongs to the N-Me-Phe pilin family
FDM99_RS01115	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FDM99_RS01120	COG1704	LemA family
FDM99_RS01130	COG0493	'glutamate synthase
FDM99_RS01135	COG0070	glutamate synthase
FDM99_RS01135	COG0067	glutamate synthase
FDM99_RS01135	COG0069	glutamate synthase activity
FDM99_RS01185	COG2226	methyltransferase
FDM99_RS01200	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDM99_RS01205	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FDM99_RS01250	COG0833	amino acid
FDM99_RS01315	COG0488	(ABC) transporter
FDM99_RS01320	COG2873	o-acetylhomoserine
FDM99_RS01325	COG4221	oxidoreductase activity
FDM99_RS01330	COG0659	secondary active sulfate transmembrane transporter activity
FDM99_RS01355	COG0427	acetyl-CoA hydrolase
FDM99_RS01385	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FDM99_RS01415	COG2329	Antibiotic biosynthesis monooxygenase
FDM99_RS01515	COG0667	Aldo Keto reductase
FDM99_RS01535	COG1309	transcriptional regulator
FDM99_RS01550	COG0583	DNA-binding transcription factor activity
FDM99_RS01555	COG2814	Major facilitator Superfamily
FDM99_RS01585	COG1335	isochorismatase
FDM99_RS01595	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS01600	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDM99_RS01610	COG1113	amino acid transport
FDM99_RS01620	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDM99_RS01635	COG2814	Major facilitator Superfamily
FDM99_RS01645	COG0351	phosphomethylpyrimidine kinase
FDM99_RS01645	COG0352	thiamine-phosphate diphosphorylase activity
FDM99_RS01645	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDM99_RS01665	COG1309	transcriptional regulator
FDM99_RS01670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FDM99_RS01695	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDM99_RS01700	COG3162	membrane
FDM99_RS01705	COG2205	protein histidine kinase activity
FDM99_RS01705	COG2198	Histidine kinase
FDM99_RS01705	COG0784	Response regulator, receiver
FDM99_RS01730	COG1522	sequence-specific DNA binding
FDM99_RS01735	COG1335	isochorismatase
FDM99_RS01740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDM99_RS01750	COG0668	transmembrane transport
FDM99_RS01755	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDM99_RS01760	COG1519	Transferase
FDM99_RS01765	COG1902	pentaerythritol trinitrate reductase activity
FDM99_RS01785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDM99_RS01810	COG0426	domain, Protein
FDM99_RS01810	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDM99_RS01815	COG4774	siderophore transport
FDM99_RS01820	COG2119	membrane
FDM99_RS01830	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDM99_RS01840	COG4942	peptidase
FDM99_RS01855	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FDM99_RS01865	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FDM99_RS01885	COG0189	ligase activity
FDM99_RS01905	COG0708	Exodeoxyribonuclease III
FDM99_RS01910	COG1393	Belongs to the ArsC family
FDM99_RS01925	COG3706	GGDEF domain
FDM99_RS01960	COG2351	hydroxyisourate hydrolase activity
FDM99_RS01965	COG2233	PERMEase
FDM99_RS01975	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDM99_RS01985	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FDM99_RS01995	COG3150	esterase
FDM99_RS02020	COG2918	glutathione biosynthetic process
FDM99_RS02035	COG2733	membrane
FDM99_RS02040	COG0436	Aminotransferase
FDM99_RS02045	COG0534	Mate efflux family protein
FDM99_RS02100	COG0753	catalase activity
FDM99_RS02150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FDM99_RS02155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDM99_RS02165	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FDM99_RS02170	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDM99_RS02175	COG0546	phosphoglycolate phosphatase activity
FDM99_RS02185	COG0010	Belongs to the arginase family
FDM99_RS02225	COG0523	cobalamin synthesis protein
FDM99_RS02235	COG1113	amino acid transport
FDM99_RS02245	COG0625	glutathione transferase activity
FDM99_RS02265	COG1683	Conserved Protein
FDM99_RS02275	COG0385	Bile acid
FDM99_RS02280	COG1335	isochorismatase
FDM99_RS02285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDM99_RS02305	COG2116	formate transmembrane transporter activity
FDM99_RS02310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDM99_RS02325	COG3188	usher protein
FDM99_RS02330	COG2983	Belongs to the UPF0260 family
FDM99_RS02350	COG1194	a g-specific adenine glycosylase
FDM99_RS02365	COG2818	Glycosylase
FDM99_RS02370	COG1064	alcohol dehydrogenase
FDM99_RS02375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDM99_RS02390	COG0583	DNA-binding transcription factor activity
FDM99_RS02395	COG0656	L-ascorbic acid biosynthetic process
FDM99_RS02400	COG2814	Major facilitator Superfamily
FDM99_RS02435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDM99_RS02450	COG2233	PERMEase
FDM99_RS02455	COG0583	DNA-binding transcription factor activity
FDM99_RS02480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
FDM99_RS02490	COG0733	neurotransmitter:sodium symporter activity
FDM99_RS02500	COG0625	glutathione transferase activity
FDM99_RS02535	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDM99_RS02540	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FDM99_RS02545	COG0596	Alpha beta hydrolase
FDM99_RS02570	COG0488	(ABC) transporter
FDM99_RS02575	COG0586	Pfam SNARE associated Golgi protein
FDM99_RS02585	COG0187	DNA topoisomerase II activity
FDM99_RS02595	COG0592	DNA-directed DNA polymerase activity
FDM99_RS02620	COG0706	membrane insertase activity
FDM99_RS02635	COG1230	cation diffusion facilitator family transporter
FDM99_RS02640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDM99_RS02655	COG0402	S-adenosylhomocysteine deaminase activity
FDM99_RS02665	COG0754	glutathionylspermidine amidase activity
FDM99_RS02675	COG0861	Integral membrane protein TerC family
FDM99_RS02680	COG0671	phosphoesterase, PA-phosphatase related
FDM99_RS02690	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDM99_RS02710	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FDM99_RS02715	COG2951	lytic endotransglycosylase activity
FDM99_RS02765	COG0657	acetylesterase activity
FDM99_RS02770	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDM99_RS02810	COG1047	Peptidyl-prolyl cis-trans
FDM99_RS02820	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDM99_RS02825	COG0196	riboflavin kinase activity
FDM99_RS02835	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDM99_RS02840	COG1309	transcriptional regulator
FDM99_RS02845	COG1116	anion transmembrane transporter activity
FDM99_RS02850	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDM99_RS02855	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDM99_RS02860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDM99_RS02865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDM99_RS02885	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS02890	COG0546	phosphoglycolate phosphatase activity
FDM99_RS02945	COG3023	N-Acetylmuramoyl-L-alanine amidase
FDM99_RS02950	COG0728	peptidoglycan biosynthetic process
FDM99_RS02980	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FDM99_RS02985	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FDM99_RS02990	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FDM99_RS03035	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FDM99_RS03045	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FDM99_RS03055	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FDM99_RS03075	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDM99_RS03085	COG2186	Transcriptional regulator
FDM99_RS03095	COG0277	FAD linked oxidase domain protein
FDM99_RS03100	COG1448	Aminotransferase
FDM99_RS03110	COG1802	Transcriptional regulator
FDM99_RS03125	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FDM99_RS03165	COG3328	transposase activity
FDM99_RS03180	COG0564	pseudouridine synthase activity
FDM99_RS03220	COG0251	oxidation-reduction process
FDM99_RS03225	COG1113	amino acid transport
FDM99_RS03230	COG1113	amino acid transport
FDM99_RS03250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDM99_RS03255	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS03260	COG1024	Enoyl-CoA hydratase
FDM99_RS03265	COG1024	Enoyl-CoA hydratase
FDM99_RS03275	COG2197	response regulator
FDM99_RS03300	COG0271	Belongs to the BolA IbaG family
FDM99_RS03310	COG1192	Involved in chromosome partitioning
FDM99_RS03325	COG0586	Pfam SNARE associated Golgi protein
FDM99_RS03330	COG2259	Doxx family
FDM99_RS03335	COG4399	Belongs to the UPF0754 family
FDM99_RS03340	COG0519	Catalyzes the synthesis of GMP from XMP
FDM99_RS03340	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDM99_RS03385	COG0281	malic enzyme
FDM99_RS03390	COG2837	iron assimilation
FDM99_RS03395	COG1280	lysine exporter protein (LysE YggA)
FDM99_RS03400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDM99_RS03405	COG1121	(ABC) transporter
FDM99_RS03470	COG0386	Belongs to the glutathione peroxidase family
FDM99_RS03485	COG1309	transcriptional regulator
FDM99_RS03490	COG0697	spore germination
FDM99_RS03500	COG0758	DNA mediated transformation
FDM99_RS03535	COG1309	transcriptional regulator
FDM99_RS03570	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FDM99_RS03580	COG0655	NAD(P)H dehydrogenase (quinone) activity
FDM99_RS03615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDM99_RS03625	COG0477	Major facilitator Superfamily
FDM99_RS03635	COG1253	flavin adenine dinucleotide binding
FDM99_RS03645	COG2860	membrane
FDM99_RS03650	COG0477	Major facilitator Superfamily
FDM99_RS03660	COG0318	PFAM AMP-dependent synthetase and ligase
FDM99_RS03675	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDM99_RS03690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDM99_RS03700	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDM99_RS03705	COG0606	chelatase, subunit chli
FDM99_RS03715	COG0347	Belongs to the P(II) protein family
FDM99_RS03720	COG0004	ammonium transporteR
FDM99_RS03730	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDM99_RS03730	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDM99_RS03770	COG0795	lipopolysaccharide-transporting ATPase activity
FDM99_RS03775	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FDM99_RS03780	COG0793	Belongs to the peptidase S41A family
FDM99_RS03795	COG2197	response regulator
FDM99_RS03805	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FDM99_RS03815	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDM99_RS03820	COG4974	Belongs to the 'phage' integrase family
FDM99_RS03845	COG0772	Belongs to the SEDS family
FDM99_RS03850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDM99_RS03855	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDM99_RS03860	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDM99_RS03885	COG0697	spore germination
FDM99_RS03910	COG3275	phosphorelay sensor kinase activity
FDM99_RS03920	COG0181	hydroxymethylbilane synthase activity
FDM99_RS03965	COG1716	ATPase activity
FDM99_RS03970	COG0546	phosphoglycolate phosphatase activity
FDM99_RS04070	COG2056	Na+-H+ antiporter family
FDM99_RS04085	COG0326	Molecular chaperone. Has ATPase activity
FDM99_RS04100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FDM99_RS04165	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FDM99_RS04170	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDM99_RS04170	COG2169	Transcriptional regulator
FDM99_RS04200	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDM99_RS04210	COG0497	DNA recombination
FDM99_RS04225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDM99_RS04235	COG0237	dephospho-CoA kinase activity
FDM99_RS04300	COG1320	monovalent cation:proton antiporter activity
FDM99_RS04305	COG2212	antiporter activity
FDM99_RS04310	COG1863	multisubunit Na H antiporter MnhE subunit
FDM99_RS04315	COG0651	ATP synthesis coupled electron transport
FDM99_RS04320	COG1006	Multisubunit Na H antiporter MnhC subunit
FDM99_RS04325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDM99_RS04325	COG2111	Na H antiporter
FDM99_RS04340	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDM99_RS04345	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDM99_RS04360	COG2226	methyltransferase
FDM99_RS04380	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FDM99_RS04385	COG1074	ATP-dependent DNA helicase activity
FDM99_RS04390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDM99_RS04395	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FDM99_RS04410	COG0598	Magnesium transport protein CorA
FDM99_RS04415	COG0789	Transcriptional regulator
FDM99_RS04420	COG0484	heat shock protein binding
FDM99_RS04435	COG0475	glutathione-regulated potassium exporter activity
FDM99_RS04435	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDM99_RS04440	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FDM99_RS04460	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDM99_RS04470	COG4535	Mg2 and Co2 transporter CorC
FDM99_RS04475	COG0425	Belongs to the sulfur carrier protein TusA family
FDM99_RS04485	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FDM99_RS04485	COG0644	oxidoreductase
FDM99_RS04495	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDM99_RS04510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDM99_RS04515	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FDM99_RS04525	COG0493	'glutamate synthase
FDM99_RS04525	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDM99_RS04555	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDM99_RS04570	COG0534	Mate efflux family protein
FDM99_RS04580	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FDM99_RS04585	COG4221	oxidoreductase activity
FDM99_RS04590	COG0583	DNA-binding transcription factor activity
FDM99_RS04600	COG0318	PFAM AMP-dependent synthetase and ligase
FDM99_RS04605	COG1530	ribonuclease E activity
FDM99_RS04620	COG0546	phosphoglycolate phosphatase activity
FDM99_RS04625	COG2378	regulation of single-species biofilm formation
FDM99_RS04630	COG0625	glutathione transferase activity
FDM99_RS04640	COG0583	DNA-binding transcription factor activity
FDM99_RS04705	COG0473	3-isopropylmalate dehydrogenase activity
FDM99_RS04760	COG1301	dicarboxylic acid transport
FDM99_RS04775	COG1280	lysine exporter protein (LysE YggA)
FDM99_RS04780	COG0488	(ABC) transporter
FDM99_RS04785	COG2900	Belongs to the SlyX family
FDM99_RS04795	COG1733	regulation of RNA biosynthetic process
FDM99_RS04820	COG0210	DNA helicase
FDM99_RS04825	COG0724	RNA recognition motif
FDM99_RS04845	COG4651	solute:proton antiporter activity
FDM99_RS04845	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDM99_RS05005	COG4651	solute:proton antiporter activity
FDM99_RS05005	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDM99_RS05030	COG0788	formyltetrahydrofolate deformylase activity
FDM99_RS05130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDM99_RS05130	COG2813	Specifically methylates the guanine in position
FDM99_RS05150	COG4774	siderophore transport
FDM99_RS05160	COG0740	serine-type endopeptidase activity
FDM99_RS05180	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FDM99_RS05180	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FDM99_RS05185	COG0280	phosphate acetyltransferase
FDM99_RS05185	COG0857	belongs to the CobB CobQ family
FDM99_RS05190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDM99_RS05200	COG0800	Aldolase
FDM99_RS05210	COG3265	gluconokinase activity
FDM99_RS05215	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS05225	COG2267	carboxylic ester hydrolase activity
FDM99_RS05240	COG0793	Belongs to the peptidase S41A family
FDM99_RS05275	COG1426	Protein conserved in bacteria
FDM99_RS05320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDM99_RS05330	COG0318	PFAM AMP-dependent synthetase and ligase
FDM99_RS05335	COG1216	Glycosyl transferase, family 2
FDM99_RS05345	COG2986	histidine ammonia-lyase
FDM99_RS05385	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS05390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FDM99_RS05410	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDM99_RS05420	COG1162	GTPase activity
FDM99_RS05425	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FDM99_RS05440	COG1538	Outer membrane efflux protein
FDM99_RS05445	COG1136	(ABC) transporter
FDM99_RS05445	COG0577	efflux transmembrane transporter activity
FDM99_RS05450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDM99_RS05475	COG0028	Belongs to the TPP enzyme family
FDM99_RS05480	COG0440	acetolactate synthase activity
FDM99_RS05515	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDM99_RS05530	COG0084	hydrolase, TatD family'
FDM99_RS05540	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FDM99_RS05550	COG0583	DNA-binding transcription factor activity
FDM99_RS05560	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDM99_RS05590	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDM99_RS05610	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDM99_RS05615	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS05620	COG3118	belongs to the thioredoxin family
FDM99_RS05625	COG1902	pentaerythritol trinitrate reductase activity
FDM99_RS05645	COG1294	oxidase, subunit
FDM99_RS05650	COG1271	oxidase subunit
FDM99_RS05670	COG4772	TonB-dependent receptor
FDM99_RS05680	COG2814	Major facilitator Superfamily
FDM99_RS05690	COG0697	spore germination
FDM99_RS05725	COG3622	Belongs to the hyi family
FDM99_RS05730	COG2084	Dehydrogenase
FDM99_RS05735	COG1024	Enoyl-CoA hydratase
FDM99_RS05740	COG0784	Response regulator, receiver
FDM99_RS05740	COG5002	protein histidine kinase activity
FDM99_RS05740	COG2205	protein histidine kinase activity
FDM99_RS05760	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDM99_RS05770	COG3956	TIGRFAM MazG family protein
FDM99_RS05775	COG1555	photosystem II stabilization
FDM99_RS05780	COG0617	tRNA 3'-terminal CCA addition
FDM99_RS05785	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDM99_RS05805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDM99_RS05810	COG3028	Belongs to the UPF0307 family
FDM99_RS05815	COG0318	PFAM AMP-dependent synthetase and ligase
FDM99_RS05830	COG0625	glutathione transferase activity
FDM99_RS05835	COG1238	metal cluster binding
FDM99_RS05905	COG0248	Ppx GppA phosphatase
FDM99_RS05915	COG0037	tRNA processing
FDM99_RS05955	COG1764	response to oxidative stress
FDM99_RS05960	COG1846	Transcriptional regulator
FDM99_RS05970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDM99_RS06030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDM99_RS06035	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDM99_RS06040	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FDM99_RS06050	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDM99_RS06080	COG1214	PFAM Peptidase M22, glycoprotease
FDM99_RS06105	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FDM99_RS06110	COG0561	phosphatase activity
FDM99_RS06120	COG2132	Multicopper oxidase
FDM99_RS06140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDM99_RS06145	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FDM99_RS06150	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FDM99_RS06185	COG0583	DNA-binding transcription factor activity
FDM99_RS06190	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS06195	COG2814	Major facilitator Superfamily
FDM99_RS06200	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDM99_RS06210	COG1053	succinate dehydrogenase
FDM99_RS06215	COG0583	DNA-binding transcription factor activity
FDM99_RS06235	COG0583	DNA-binding transcription factor activity
FDM99_RS06270	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDM99_RS06315	COG4993	Dehydrogenase
FDM99_RS06335	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS06405	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDM99_RS06425	COG0745	RESPONSE REGULATOR receiver
FDM99_RS06465	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FDM99_RS06495	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDM99_RS06500	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FDM99_RS06520	COG0583	DNA-binding transcription factor activity
FDM99_RS06540	COG0668	transmembrane transport
FDM99_RS06550	COG2081	HI0933 family
FDM99_RS06555	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FDM99_RS06590	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDM99_RS06590	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDM99_RS06600	COG0489	protein tyrosine kinase activity
FDM99_RS06660	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDM99_RS06670	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDM99_RS06685	COG0730	response to heat
FDM99_RS06695	COG1196	nuclear chromosome segregation
FDM99_RS06715	COG2223	nitrite transmembrane transporter activity
FDM99_RS06720	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FDM99_RS06725	COG1877	trehalose-phosphatase activity
FDM99_RS06730	COG0596	Alpha beta hydrolase
FDM99_RS06730	COG2226	methyltransferase
FDM99_RS06730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDM99_RS06745	COG4106	trans-aconitate 2-methyltransferase activity
FDM99_RS06760	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FDM99_RS06765	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FDM99_RS06775	COG3101	peptidyl-lysine hydroxylation
FDM99_RS06780	COG1399	metal-binding, possibly nucleic acid-binding protein
FDM99_RS06805	COG1652	LysM domain
FDM99_RS06810	COG0352	thiamine-phosphate diphosphorylase activity
FDM99_RS06810	COG0351	phosphomethylpyrimidine kinase
FDM99_RS06810	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDM99_RS06820	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDM99_RS06850	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDM99_RS06880	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FDM99_RS06895	COG0358	DNA primase activity
FDM99_RS06905	COG0564	pseudouridine synthase activity
FDM99_RS06930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDM99_RS06950	COG0583	DNA-binding transcription factor activity
FDM99_RS06955	COG0473	3-isopropylmalate dehydrogenase activity
FDM99_RS06965	COG0657	acetylesterase activity
FDM99_RS06975	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS06995	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDM99_RS06995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDM99_RS07010	COG1981	membrane
FDM99_RS07055	COG0456	acetyltransferase
FDM99_RS07065	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FDM99_RS07070	COG0492	ferredoxin-NADP+ reductase activity
FDM99_RS07075	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FDM99_RS07075	COG1674	ftsk spoiiie
FDM99_RS07080	COG1280	lysine exporter protein (LysE YggA)
FDM99_RS07095	COG2894	cell division
FDM99_RS07110	COG0204	Acyl-transferase
FDM99_RS07115	COG2885	chlorophyll binding
FDM99_RS07120	COG0210	DNA helicase
FDM99_RS07130	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDM99_RS07145	COG0121	glutamine amidotransferase
FDM99_RS07170	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDM99_RS07175	COG0735	belongs to the Fur family
FDM99_RS07200	COG0420	3'-5' exonuclease activity
FDM99_RS07225	COG1090	epimerase
FDM99_RS07240	COG2050	protein possibly involved in aromatic compounds catabolism
FDM99_RS07250	COG2814	Major facilitator Superfamily
FDM99_RS07255	COG0405	Gamma-glutamyltransferase
FDM99_RS07265	COG0582	viral genome integration into host DNA
FDM99_RS07345	COG0477	Major facilitator Superfamily
FDM99_RS07350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDM99_RS07400	COG0531	amino acid
FDM99_RS07405	COG2040	homocysteine
FDM99_RS07430	COG1309	transcriptional regulator
FDM99_RS07440	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDM99_RS07450	COG1607	acyl-coa hydrolase
FDM99_RS07460	COG0523	cobalamin synthesis protein
FDM99_RS07470	COG4681	YaeQ
FDM99_RS07480	COG1649	PFAM Uncharacterised BCR, COG1649
FDM99_RS07480	COG0726	polysaccharide deacetylase
FDM99_RS07485	COG1215	transferase activity, transferring glycosyl groups
FDM99_RS07495	COG1024	Enoyl-CoA hydratase
FDM99_RS07510	COG1414	Transcriptional regulator
FDM99_RS07530	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS07540	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDM99_RS07545	COG2271	Major facilitator Superfamily
FDM99_RS07555	COG2267	carboxylic ester hydrolase activity
FDM99_RS07560	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS07575	COG0028	Belongs to the TPP enzyme family
FDM99_RS07585	COG0477	Major facilitator Superfamily
FDM99_RS07590	COG0242	peptide deformylase activity
FDM99_RS07595	COG2066	Belongs to the glutaminase family
FDM99_RS07600	COG2207	Transcriptional regulator
FDM99_RS07605	COG2223	nitrite transmembrane transporter activity
FDM99_RS07625	COG0583	DNA-binding transcription factor activity
FDM99_RS07630	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS07635	COG2271	Major facilitator Superfamily
FDM99_RS07640	COG3959	Transketolase, thiamine diphosphate binding domain
FDM99_RS07645	COG3958	Transketolase
FDM99_RS07655	COG0306	phosphate transporter
FDM99_RS07675	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDM99_RS07720	COG4181	ATPase activity
FDM99_RS07725	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FDM99_RS07755	COG0583	DNA-binding transcription factor activity
FDM99_RS07760	COG2267	carboxylic ester hydrolase activity
FDM99_RS07765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDM99_RS07770	COG1773	rubredoxin
FDM99_RS07820	COG2851	Citrate transporter
FDM99_RS07830	COG1253	flavin adenine dinucleotide binding
FDM99_RS07870	COG0804	urea catabolic process
FDM99_RS07880	COG0830	nickel cation binding
FDM99_RS07895	COG0742	ribosomal rna small subunit methyltransferase
FDM99_RS07900	COG0768	penicillin binding
FDM99_RS07925	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDM99_RS07930	COG2878	Part of a membrane complex involved in electron transport
FDM99_RS07935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDM99_RS07945	COG3384	dioxygenase
FDM99_RS07965	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDM99_RS08005	COG0006	proline dipeptidase activity
FDM99_RS08010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDM99_RS08015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDM99_RS08035	COG1279	arginine transmembrane transporter activity
FDM99_RS08040	COG0583	DNA-binding transcription factor activity
FDM99_RS08090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDM99_RS08095	COG1388	LysM domain
FDM99_RS08095	COG0741	lytic transglycosylase activity
FDM99_RS08095	COG1388	LysM domain
FDM99_RS08095	COG0741	lytic transglycosylase activity
FDM99_RS08105	COG4174	ABC transporter (Permease)
FDM99_RS08110	COG4239	(ABC) transporter, permease
FDM99_RS08115	COG4172	Belongs to the ABC transporter superfamily
FDM99_RS08135	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDM99_RS08145	COG4251	negative regulation of phosphorylation
FDM99_RS08145	COG2203	Gaf domain
FDM99_RS08145	COG3706	GGDEF domain
FDM99_RS08145	COG5001	Diguanylate cyclase
FDM99_RS08155	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDM99_RS08155	COG1902	pentaerythritol trinitrate reductase activity
FDM99_RS08165	COG0583	DNA-binding transcription factor activity
FDM99_RS08170	COG2851	Citrate transporter
FDM99_RS08200	COG2423	ornithine cyclodeaminase activity
FDM99_RS08210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDM99_RS08215	COG2197	response regulator
FDM99_RS08255	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDM99_RS08265	COG1414	Transcriptional regulator
FDM99_RS08270	COG0028	Belongs to the TPP enzyme family
FDM99_RS08275	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS08280	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS08330	COG4269	membrane
FDM99_RS08355	COG3209	COG3209 Rhs family protein
FDM99_RS08425	COG1113	amino acid transport
FDM99_RS08435	COG0531	amino acid
FDM99_RS08455	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS08475	COG1113	amino acid transport
FDM99_RS08500	COG0697	spore germination
FDM99_RS08505	COG2721	sulfolactate sulfo-lyase activity
FDM99_RS08510	COG2271	Major facilitator Superfamily
FDM99_RS08525	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS08530	COG2186	Transcriptional regulator
FDM99_RS08555	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS08565	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS08570	COG1024	Enoyl-CoA hydratase
FDM99_RS08575	COG2814	Major facilitator Superfamily
FDM99_RS08590	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDM99_RS08635	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FDM99_RS08645	COG0300	oxidoreductase activity
FDM99_RS08655	COG1309	transcriptional regulator
FDM99_RS08660	COG1741	Belongs to the pirin family
FDM99_RS08675	COG2072	flavoprotein involved in K transport
FDM99_RS08685	COG2252	PERMEase
FDM99_RS08690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDM99_RS08695	COG3038	cytochrome b561
FDM99_RS08705	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FDM99_RS08715	COG0527	aspartate kinase activity
FDM99_RS08725	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDM99_RS08735	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDM99_RS08750	COG0667	Aldo Keto reductase
FDM99_RS08760	COG1765	OsmC-like protein
FDM99_RS08775	COG0542	response to heat
FDM99_RS08810	COG2885	chlorophyll binding
FDM99_RS08820	COG0625	glutathione transferase activity
FDM99_RS08825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDM99_RS08845	COG3634	alkyl hydroperoxide reductase activity
FDM99_RS08855	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FDM99_RS08865	COG0450	alkyl hydroperoxide reductase
FDM99_RS08870	COG1643	Atp-dependent helicase
FDM99_RS08885	COG2814	Major facilitator Superfamily
FDM99_RS08890	COG3135	benzoate transporter
FDM99_RS08895	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS08900	COG0543	2 iron, 2 sulfur cluster binding
FDM99_RS08900	COG0633	Ferredoxin
FDM99_RS08905	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDM99_RS08910	COG4638	Rieske (2fe-2S)
FDM99_RS08915	COG0583	DNA-binding transcription factor activity
FDM99_RS08970	COG1570	exodeoxyribonuclease VII activity
FDM99_RS09010	COG1278	Cold shock
FDM99_RS09210	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDM99_RS09210	COG0517	IMP dehydrogenase activity
FDM99_RS09215	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FDM99_RS09225	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FDM99_RS09230	COG1137	ATPase activity
FDM99_RS09235	COG1538	Outer membrane efflux protein
FDM99_RS09265	COG4122	O-methyltransferase activity
FDM99_RS09275	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FDM99_RS09335	COG0583	DNA-binding transcription factor activity
FDM99_RS09345	COG0006	proline dipeptidase activity
FDM99_RS09350	COG0477	Major facilitator Superfamily
FDM99_RS09365	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS09370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDM99_RS09375	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDM99_RS09375	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FDM99_RS09410	COG2814	Major facilitator Superfamily
FDM99_RS09415	COG4948	Mandelate Racemase Muconate Lactonizing
FDM99_RS09425	COG1309	transcriptional regulator
FDM99_RS09465	COG1309	transcriptional regulator
FDM99_RS09495	COG2610	gluconate transmembrane transporter activity
FDM99_RS09500	COG1454	alcohol dehydrogenase
FDM99_RS09510	COG1414	Transcriptional regulator
FDM99_RS09530	COG3123	guanosine phosphorylase activity
FDM99_RS09535	COG1522	sequence-specific DNA binding
FDM99_RS09540	COG5006	permease, DMT superfamily
FDM99_RS09550	COG1560	Kdo2-lipid A biosynthetic process
FDM99_RS09560	COG1309	transcriptional regulator
FDM99_RS09585	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDM99_RS09630	COG3209	COG3209 Rhs family protein
FDM99_RS09660	COG0583	DNA-binding transcription factor activity
FDM99_RS09665	COG1914	H( )-stimulated, divalent metal cation uptake system
FDM99_RS09685	COG4770	biotin carboxylase activity
FDM99_RS09690	COG0038	chloride channel
FDM99_RS09715	COG1309	transcriptional regulator
FDM99_RS09725	COG1063	alcohol dehydrogenase
FDM99_RS09740	COG0439	Biotin carboxylase
FDM99_RS09745	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDM99_RS09750	COG1733	regulation of RNA biosynthetic process
FDM99_RS09760	COG0864	Transcriptional regulator
FDM99_RS09770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDM99_RS09775	COG1116	anion transmembrane transporter activity
FDM99_RS09895	COG0590	tRNA wobble adenosine to inosine editing
FDM99_RS09900	COG2807	transmembrane transport
FDM99_RS09915	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FDM99_RS09925	COG0789	Transcriptional regulator
FDM99_RS09940	COG1760	l-serine dehydratase
FDM99_RS09945	COG2030	dehydratase
FDM99_RS09945	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS09950	COG3396	Phenylacetate-CoA oxygenase
FDM99_RS09955	COG3460	Phenylacetate-CoA oxygenase
FDM99_RS09960	COG3396	Phenylacetate-CoA oxygenase
FDM99_RS09965	COG2151	metal-sulfur cluster biosynthetic enzyme
FDM99_RS09970	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDM99_RS09975	COG1024	Enoyl-CoA hydratase
FDM99_RS09980	COG1024	Enoyl-CoA hydratase
FDM99_RS09985	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDM99_RS09990	COG0183	Belongs to the thiolase family
FDM99_RS09995	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FDM99_RS10000	COG3327	negative regulation of DNA-templated transcription, initiation
FDM99_RS10010	COG2050	protein possibly involved in aromatic compounds catabolism
FDM99_RS10040	COG3038	cytochrome b561
FDM99_RS10060	COG2267	carboxylic ester hydrolase activity
FDM99_RS10065	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDM99_RS10070	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDM99_RS10075	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS10085	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDM99_RS10095	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS10100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDM99_RS10105	COG0583	DNA-binding transcription factor activity
FDM99_RS10115	COG1414	Transcriptional regulator
FDM99_RS10120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDM99_RS10135	COG1840	ABC-type Fe3 transport system, periplasmic component
FDM99_RS10140	COG3842	ATPase activity
FDM99_RS10155	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FDM99_RS10160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDM99_RS10180	COG0583	DNA-binding transcription factor activity
FDM99_RS10190	COG4770	biotin carboxylase activity
FDM99_RS10195	COG1024	Enoyl-CoA hydratase
FDM99_RS10200	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDM99_RS10205	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS10210	COG1309	transcriptional regulator
FDM99_RS10215	COG0318	PFAM AMP-dependent synthetase and ligase
FDM99_RS10235	COG0583	DNA-binding transcription factor activity
FDM99_RS10280	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS10300	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDM99_RS10320	COG2205	protein histidine kinase activity
FDM99_RS10320	COG0784	Response regulator, receiver
FDM99_RS10340	COG0765	amino acid transport
FDM99_RS10345	COG0765	amino acid transport
FDM99_RS10350	COG1126	abc transporter atp-binding protein
FDM99_RS10355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDM99_RS10360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDM99_RS10370	COG1280	lysine exporter protein (LysE YggA)
FDM99_RS10375	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FDM99_RS10380	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDM99_RS10400	COG0583	DNA-binding transcription factor activity
FDM99_RS10405	COG0625	glutathione transferase activity
FDM99_RS10410	COG0625	glutathione transferase activity
FDM99_RS10415	COG0583	DNA-binding transcription factor activity
FDM99_RS10425	COG1346	cytolysis
FDM99_RS10445	COG2814	Major facilitator Superfamily
FDM99_RS10455	COG0583	DNA-binding transcription factor activity
FDM99_RS10465	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FDM99_RS10470	COG3052	prosthetic group binding
FDM99_RS10490	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FDM99_RS10510	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDM99_RS10520	COG1294	oxidase, subunit
FDM99_RS10525	COG1271	oxidase subunit
FDM99_RS10550	COG0477	Major facilitator Superfamily
FDM99_RS10560	COG4521	taurine ABC transporter
FDM99_RS10565	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FDM99_RS10570	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDM99_RS10575	COG2175	clavaminate synthase activity
FDM99_RS10585	COG1953	Uracil, thiamine, allantoin
FDM99_RS10595	COG0583	DNA-binding transcription factor activity
FDM99_RS10605	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FDM99_RS10620	COG0640	Transcriptional regulator
FDM99_RS10625	COG0798	PFAM Bile acid sodium symporter
FDM99_RS10630	COG0583	DNA-binding transcription factor activity
FDM99_RS10645	COG3634	alkyl hydroperoxide reductase activity
FDM99_RS10680	COG1301	dicarboxylic acid transport
FDM99_RS10685	COG0436	Aminotransferase
FDM99_RS10695	COG0386	Belongs to the glutathione peroxidase family
FDM99_RS10735	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDM99_RS10760	COG0012	GTP binding
FDM99_RS10765	COG2011	ABC-type metal ion transport system permease component
FDM99_RS10770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDM99_RS10780	COG1464	Belongs to the NlpA lipoprotein family
FDM99_RS10810	COG0765	amino acid transport
FDM99_RS10815	COG0765	amino acid transport
FDM99_RS10820	COG1126	abc transporter atp-binding protein
FDM99_RS10830	COG1522	sequence-specific DNA binding
FDM99_RS10845	COG1309	transcriptional regulator
FDM99_RS10895	COG3121	Chaperone
FDM99_RS10900	COG3539	Fimbrial protein
FDM99_RS10925	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FDM99_RS10925	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FDM99_RS10970	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDM99_RS10980	COG2353	YceI-like domain
FDM99_RS10990	COG3698	Phosphodiester glycosidase
FDM99_RS11005	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FDM99_RS11010	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDM99_RS11010	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDM99_RS11010	COG0506	proline dehydrogenase activity
FDM99_RS11020	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDM99_RS11025	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDM99_RS11045	COG1132	(ABC) transporter
FDM99_RS11050	COG3122	Protein conserved in bacteria
FDM99_RS11055	COG3619	membrane
FDM99_RS11065	COG0640	Transcriptional regulator
FDM99_RS11075	COG2850	peptidyl-arginine hydroxylation
FDM99_RS11080	COG0424	maF-like protein
FDM99_RS11100	COG0191	fructose-bisphosphate aldolase activity
FDM99_RS11120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDM99_RS11130	COG1192	Involved in chromosome partitioning
FDM99_RS11135	COG1475	DNA binding
FDM99_RS11140	COG0811	peptide transport
FDM99_RS11150	COG1132	(ABC) transporter
FDM99_RS11155	COG1663	tetraacyldisaccharide 4'-kinase activity
FDM99_RS11175	COG0084	hydrolase, TatD family'
FDM99_RS11190	COG2165	general secretion pathway protein
FDM99_RS11240	COG0776	regulation of translation
FDM99_RS11270	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FDM99_RS11275	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FDM99_RS11320	COG0339	signal peptide processing
FDM99_RS11330	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDM99_RS11365	COG0702	epimerase
FDM99_RS11370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDM99_RS11390	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FDM99_RS11420	COG0316	Belongs to the HesB IscA family
FDM99_RS11425	COG0822	iron-sulfur transferase activity
FDM99_RS11455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDM99_RS11460	COG2207	Transcriptional regulator
FDM99_RS11470	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS11475	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS11490	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDM99_RS11505	COG2814	Major facilitator Superfamily
FDM99_RS11515	COG4264	IucA IucC family
FDM99_RS11525	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDM99_RS11575	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FDM99_RS11580	COG0406	alpha-ribazole phosphatase activity
FDM99_RS11595	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDM99_RS11600	COG0730	response to heat
FDM99_RS11620	COG4773	Receptor
FDM99_RS11625	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDM99_RS11640	COG1131	(ABC) transporter
FDM99_RS11645	COG0842	Transport permease protein
FDM99_RS11650	COG0842	Transport permease protein
FDM99_RS11710	COG2226	methyltransferase
FDM99_RS11735	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDM99_RS11770	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDM99_RS11780	COG0133	tryptophan synthase activity
FDM99_RS11795	COG3706	GGDEF domain
FDM99_RS11810	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDM99_RS11815	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FDM99_RS11820	COG0022	dehydrogenase e1 component
FDM99_RS11825	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDM99_RS11830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDM99_RS11840	COG1063	alcohol dehydrogenase
FDM99_RS11845	COG3781	membrane
FDM99_RS11855	COG3453	Protein conserved in bacteria
FDM99_RS11855	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDM99_RS11865	COG0730	response to heat
FDM99_RS11880	COG3708	Transcriptional regulator
FDM99_RS11880	COG2207	Transcriptional regulator
FDM99_RS11885	COG1733	regulation of RNA biosynthetic process
FDM99_RS11890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDM99_RS11900	COG2188	Transcriptional regulator
FDM99_RS11915	COG4521	taurine ABC transporter
FDM99_RS11920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDM99_RS11940	COG0477	Major facilitator Superfamily
FDM99_RS11950	COG1027	Aspartate ammonia-lyase
FDM99_RS11965	COG0583	DNA-binding transcription factor activity
FDM99_RS11970	COG0583	DNA-binding transcription factor activity
FDM99_RS11975	COG0183	Belongs to the thiolase family
FDM99_RS11980	COG2031	fatty acid transporter
FDM99_RS11995	COG0583	DNA-binding transcription factor activity
FDM99_RS12025	COG2610	gluconate transmembrane transporter activity
FDM99_RS12030	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS12035	COG2207	Transcriptional regulator
FDM99_RS12050	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS12060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDM99_RS12075	COG0543	2 iron, 2 sulfur cluster binding
FDM99_RS12075	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDM99_RS12080	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDM99_RS12085	COG4638	Rieske (2fe-2S)
FDM99_RS12095	COG0725	ABC transporter, periplasmic molybdate-binding protein
FDM99_RS12100	COG4149	molybdate abc transporter
FDM99_RS12105	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FDM99_RS12110	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS12115	COG1535	isochorismatase
FDM99_RS12115	COG3433	isochorismatase activity
FDM99_RS12180	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDM99_RS12195	COG0753	catalase activity
FDM99_RS12205	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FDM99_RS12255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDM99_RS12275	COG1120	ATPase activity
FDM99_RS12280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDM99_RS12290	COG1064	alcohol dehydrogenase
FDM99_RS12295	COG2207	Transcriptional regulator
FDM99_RS12300	COG2084	Dehydrogenase
FDM99_RS12310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDM99_RS12315	COG0583	DNA-binding transcription factor activity
FDM99_RS12325	COG0129	dihydroxy-acid dehydratase activity
FDM99_RS12330	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS12345	COG1566	PFAM secretion protein HlyD family protein
FDM99_RS12355	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDM99_RS12380	COG2188	Transcriptional regulator
FDM99_RS12440	COG0318	PFAM AMP-dependent synthetase and ligase
FDM99_RS12450	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS12465	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS12470	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS12475	COG0583	DNA-binding transcription factor activity
FDM99_RS12480	COG1309	transcriptional regulator
FDM99_RS12520	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDM99_RS12520	COG1902	pentaerythritol trinitrate reductase activity
FDM99_RS12555	COG2186	Transcriptional regulator
FDM99_RS12565	COG0583	DNA-binding transcription factor activity
FDM99_RS12570	COG4948	Mandelate Racemase Muconate Lactonizing
FDM99_RS12575	COG4829	muconolactone delta-isomerase
FDM99_RS12595	COG0183	Belongs to the thiolase family
FDM99_RS12600	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDM99_RS12610	COG1012	belongs to the aldehyde dehydrogenase family
FDM99_RS12620	COG3733	amine oxidase
FDM99_RS12630	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDM99_RS12640	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS12650	COG4638	Rieske (2fe-2S)
FDM99_RS12670	COG0154	amidase activity
FDM99_RS12705	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS12710	COG0583	DNA-binding transcription factor activity
FDM99_RS12715	COG1414	Transcriptional regulator
FDM99_RS12730	COG2391	methyltransferase activity
FDM99_RS12740	COG4993	Dehydrogenase
FDM99_RS12745	COG3659	wide pore channel activity
FDM99_RS12750	COG3420	alginic acid biosynthetic process
FDM99_RS12755	COG0710	3-dehydroquinate dehydratase activity
FDM99_RS12760	COG3485	protocatechuate 3,4-dioxygenase
FDM99_RS12765	COG3485	protocatechuate 3,4-dioxygenase
FDM99_RS12770	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDM99_RS12775	COG2271	Major facilitator Superfamily
FDM99_RS12780	COG0596	Alpha beta hydrolase
FDM99_RS12785	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FDM99_RS12790	COG0183	Belongs to the thiolase family
FDM99_RS12795	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDM99_RS12800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDM99_RS12810	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FDM99_RS12815	COG2323	membrane
FDM99_RS12860	COG1902	pentaerythritol trinitrate reductase activity
FDM99_RS12860	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDM99_RS12885	COG0542	response to heat
FDM99_RS12890	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FDM99_RS12920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDM99_RS12925	COG0569	domain protein
FDM99_RS12930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDM99_RS12945	COG4774	siderophore transport
FDM99_RS12950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDM99_RS12960	COG1585	Membrane protein implicated in regulation of membrane protease activity
FDM99_RS12975	COG1294	oxidase, subunit
FDM99_RS12980	COG4890	Cyd operon protein YbgT
FDM99_RS12990	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDM99_RS13000	COG0552	protein localization to endoplasmic reticulum
FDM99_RS13025	COG0516	GMP reductase activity
FDM99_RS13025	COG0517	IMP dehydrogenase activity
FDM99_RS13030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDM99_RS13035	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FDM99_RS13045	COG0583	DNA-binding transcription factor activity
FDM99_RS13050	COG0024	Methionine aminopeptidase
FDM99_RS13080	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDM99_RS13080	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDM99_RS13085	COG1105	Belongs to the carbohydrate kinase PfkB family
FDM99_RS13090	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDM99_RS13090	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDM99_RS13090	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FDM99_RS13110	COG5001	Diguanylate cyclase
FDM99_RS13110	COG3300	MHYT domain
FDM99_RS13125	COG2135	peptidase activity
FDM99_RS13130	COG0659	secondary active sulfate transmembrane transporter activity
FDM99_RS13145	COG1113	amino acid transport
FDM99_RS13155	COG1522	sequence-specific DNA binding
FDM99_RS13180	COG1011	Hydrolase
FDM99_RS13185	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDM99_RS13195	COG2137	regulation of response to DNA damage stimulus
FDM99_RS13210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDM99_RS13230	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDM99_RS13245	COG0575	Belongs to the CDS family
FDM99_RS13250	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDM99_RS13275	COG3852	Histidine kinase
FDM99_RS13280	COG2204	response regulator
FDM99_RS13340	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDM99_RS13345	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FDM99_RS13365	COG0697	spore germination
FDM99_RS13370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDM99_RS13385	COG0315	cyclic pyranopterin monophosphate synthase activity
FDM99_RS13385	COG0521	Mo-molybdopterin cofactor biosynthetic process
FDM99_RS13400	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FDM99_RS13405	COG0243	molybdopterin cofactor binding
FDM99_RS13415	COG0243	molybdopterin cofactor binding
FDM99_RS13420	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDM99_RS13425	COG2146	nitrite reductase [NAD(P)H] activity
FDM99_RS13425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDM99_RS13435	COG0745	RESPONSE REGULATOR receiver
FDM99_RS13440	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDM99_RS13440	COG1116	anion transmembrane transporter activity
FDM99_RS13460	COG0511	ligase activity, forming carbon-carbon bonds
FDM99_RS13475	COG2814	Major facilitator Superfamily
FDM99_RS13535	COG0741	lytic transglycosylase activity
FDM99_RS13535	COG0739	heme binding
FDM99_RS13535	COG1196	nuclear chromosome segregation
FDM99_RS13820	COG0069	glutamate synthase activity
FDM99_RS13850	COG1454	alcohol dehydrogenase
FDM99_RS13855	COG0824	Thioesterase
FDM99_RS13865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FDM99_RS13880	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FDM99_RS13885	COG2030	dehydratase
FDM99_RS13905	COG0583	DNA-binding transcription factor activity
FDM99_RS13910	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FDM99_RS13920	COG1522	sequence-specific DNA binding
FDM99_RS13925	COG3135	benzoate transporter
FDM99_RS13960	COG0589	response to stress
FDM99_RS13965	COG0488	(ABC) transporter
FDM99_RS13985	COG4773	Receptor
FDM99_RS14015	COG0668	transmembrane transport
FDM99_RS14025	COG1309	transcriptional regulator
FDM99_RS14045	COG1605	Chorismate mutase
FDM99_RS14085	COG0308	aminopeptidase N
FDM99_RS14105	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FDM99_RS14115	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDM99_RS14120	COG1454	alcohol dehydrogenase
FDM99_RS14140	COG0531	amino acid
FDM99_RS14145	COG4303	Ethanolamine ammonia lyase large subunit
FDM99_RS14150	COG4302	ethanolamine ammonia-lyase activity
FDM99_RS14155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDM99_RS14155	COG0519	Catalyzes the synthesis of GMP from XMP
FDM99_RS14160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDM99_RS14170	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDM99_RS14185	COG0697	spore germination
FDM99_RS14190	COG1923	regulation of RNA biosynthetic process
FDM99_RS14200	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDM99_RS14205	COG0802	atpase or kinase
FDM99_RS14225	COG1187	pseudouridine synthase activity
FDM99_RS14240	COG0583	DNA-binding transcription factor activity
FDM99_RS14255	COG2814	Major facilitator Superfamily
FDM99_RS14260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDM99_RS14290	COG0729	surface antigen
FDM99_RS14310	COG0174	glutamine synthetase
FDM99_RS14315	COG0745	RESPONSE REGULATOR receiver
FDM99_RS14320	COG2205	protein histidine kinase activity
FDM99_RS14330	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FDM99_RS14335	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FDM99_RS14360	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDM99_RS14365	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDM99_RS14370	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS14400	COG0583	DNA-binding transcription factor activity
FDM99_RS14420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDM99_RS14430	COG3658	cytochrome
FDM99_RS14435	COG1215	transferase activity, transferring glycosyl groups
FDM99_RS14440	COG1649	PFAM Uncharacterised BCR, COG1649
FDM99_RS14440	COG0726	polysaccharide deacetylase
FDM99_RS14475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDM99_RS14480	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FDM99_RS14490	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FDM99_RS14515	COG0305	Participates in initiation and elongation during chromosome replication
FDM99_RS14520	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDM99_RS14530	COG1305	Transglutaminase-like
FDM99_RS14540	COG2308	Evidence 4 Homologs of previously reported genes of
FDM99_RS14570	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FDM99_RS14575	COG0138	bifunctional purine biosynthesis protein purh
FDM99_RS14580	COG0151	Belongs to the GarS family
FDM99_RS14585	COG1464	Belongs to the NlpA lipoprotein family
FDM99_RS14590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDM99_RS14595	COG2011	ABC-type metal ion transport system permease component
FDM99_RS14600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDM99_RS14610	COG1301	dicarboxylic acid transport
FDM99_RS14640	COG1794	racemase activity, acting on amino acids and derivatives
FDM99_RS14660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDM99_RS14660	COG3008	intermembrane lipid transfer
FDM99_RS14665	COG2995	paraquat-inducible protein a
FDM99_RS14695	COG0477	Major facilitator Superfamily
FDM99_RS14710	COG2186	Transcriptional regulator
FDM99_RS14720	COG0786	glutamate:sodium symporter activity
FDM99_RS14725	COG3243	poly(R)-hydroxyalkanoic acid synthase
FDM99_RS14750	COG3111	PFAM Bacterial OB fold (BOF) protein
FDM99_RS14850	COG1610	YqeY-like protein
FDM99_RS14855	COG4783	chaperone-mediated protein folding
FDM99_RS14880	COG1286	toxin biosynthetic process
FDM99_RS14910	COG0778	Nitroreductase
FDM99_RS14920	COG0513	Belongs to the DEAD box helicase family
FDM99_RS14940	COG2363	Small membrane protein
FDM99_RS14970	COG1234	tRNA 3'-trailer cleavage
FDM99_RS14975	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDM99_RS14985	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FDM99_RS14995	COG2819	hydrolase of the alpha beta superfamily
FDM99_RS15000	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS15005	COG1301	dicarboxylic acid transport
FDM99_RS15015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FDM99_RS15020	COG3139	Protein of unknown function (DUF1315)
FDM99_RS15025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FDM99_RS15030	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDM99_RS15040	COG0494	nUDIX hydrolase
FDM99_RS15050	COG0642	Histidine kinase
FDM99_RS15065	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDM99_RS15075	COG1720	tRNA m6t6A37 methyltransferase activity
FDM99_RS15090	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDM99_RS15095	COG0826	peptidase U32
FDM99_RS15100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDM99_RS15110	COG4598	ABC transporter
FDM99_RS15115	COG4160	amino acid transport
FDM99_RS15120	COG4215	(ABC) transporter
FDM99_RS15135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDM99_RS15180	COG1131	(ABC) transporter
FDM99_RS15185	COG0842	Transport permease protein
FDM99_RS15200	COG0772	Belongs to the SEDS family
FDM99_RS15205	COG2951	lytic endotransglycosylase activity
FDM99_RS15230	COG2207	Transcriptional regulator
FDM99_RS15245	COG0052	Belongs to the universal ribosomal protein uS2 family
FDM99_RS15250	COG0024	Methionine aminopeptidase
FDM99_RS15260	COG2223	nitrite transmembrane transporter activity
FDM99_RS15270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDM99_RS15275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDM99_RS15280	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS15295	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FDM99_RS15300	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FDM99_RS15305	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDM99_RS15325	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDM99_RS15330	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDM99_RS15335	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FDM99_RS15370	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FDM99_RS15380	COG0174	glutamine synthetase
FDM99_RS15395	COG0512	Glutamine amidotransferase of anthranilate synthase
FDM99_RS15400	COG0308	aminopeptidase N
FDM99_RS15430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FDM99_RS15440	COG0302	gtp cyclohydrolase
FDM99_RS15460	COG3739	integral membrane protein
FDM99_RS15485	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FDM99_RS15490	COG1132	(ABC) transporter
FDM99_RS15495	COG1132	(ABC) transporter
FDM99_RS15510	COG1535	isochorismatase
FDM99_RS15510	COG3433	isochorismatase activity
FDM99_RS15515	COG1021	2,3-dihydroxybenzoate-AMP ligase
FDM99_RS15520	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDM99_RS15530	COG4774	siderophore transport
FDM99_RS15535	COG4607	ABC-type enterochelin transport system periplasmic component
FDM99_RS15540	COG4604	ABC transporter, ATP-binding protein
FDM99_RS15545	COG4605	iron ion homeostasis
FDM99_RS15550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDM99_RS15555	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDM99_RS15570	COG2964	Protein conserved in bacteria
FDM99_RS15580	COG1741	Belongs to the pirin family
FDM99_RS15600	COG4214	carbohydrate transport
FDM99_RS15615	COG0673	inositol 2-dehydrogenase activity
FDM99_RS15630	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS15635	COG2814	Major facilitator Superfamily
FDM99_RS15645	COG2814	Major facilitator Superfamily
FDM99_RS15655	COG0583	DNA-binding transcription factor activity
FDM99_RS15660	COG3485	protocatechuate 3,4-dioxygenase
FDM99_RS15665	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDM99_RS15670	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDM99_RS15675	COG0183	Belongs to the thiolase family
FDM99_RS15710	COG2879	small protein
FDM99_RS15715	COG1966	Carbon starvation protein
FDM99_RS15735	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FDM99_RS15760	COG1067	ATP-dependent peptidase activity
FDM99_RS15765	COG0583	DNA-binding transcription factor activity
FDM99_RS15790	COG1686	Belongs to the peptidase S11 family
FDM99_RS15795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDM99_RS15830	COG0616	signal peptide processing
FDM99_RS15835	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDM99_RS15845	COG0573	inorganic phosphate transmembrane transporter activity
FDM99_RS15850	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FDM99_RS15855	COG1113	amino acid transport
FDM99_RS15860	COG3961	Belongs to the TPP enzyme family
FDM99_RS15865	COG1522	sequence-specific DNA binding
FDM99_RS15875	COG0076	glutamate decarboxylase activity
FDM99_RS15880	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDM99_RS15895	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDM99_RS15905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDM99_RS15940	COG0352	thiamine-phosphate diphosphorylase activity
FDM99_RS15965	COG0612	Peptidase, M16
FDM99_RS15975	COG1823	symporter activity
FDM99_RS15980	COG0583	DNA-binding transcription factor activity
FDM99_RS15985	COG0477	Major facilitator Superfamily
FDM99_RS16010	COG1187	pseudouridine synthase activity
FDM99_RS16025	COG1686	Belongs to the peptidase S11 family
FDM99_RS16030	COG1252	NADH dehydrogenase
FDM99_RS16040	COG0415	Belongs to the DNA photolyase family
FDM99_RS16055	COG1215	transferase activity, transferring glycosyl groups
FDM99_RS16085	COG2070	2-Nitropropane dioxygenase
FDM99_RS16140	COG0556	nucleotide-excision repair
FDM99_RS16160	COG0436	Aminotransferase
FDM99_RS16170	COG0443	Heat shock 70 kDa protein
FDM99_RS16200	COG4221	oxidoreductase activity
FDM99_RS16210	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FDM99_RS16215	COG1381	Involved in DNA repair and RecF pathway recombination
FDM99_RS16225	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDM99_RS16240	COG0681	Belongs to the peptidase S26 family
FDM99_RS16250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDM99_RS16260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDM99_RS16280	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FDM99_RS16285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDM99_RS16300	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FDM99_RS16305	COG4208	sulfate ABC transporter
FDM99_RS16310	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FDM99_RS16315	COG0583	DNA-binding transcription factor activity
FDM99_RS16320	COG4625	pathogenesis
FDM99_RS16335	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FDM99_RS16350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDM99_RS16360	COG1051	belongs to the nudix hydrolase family
FDM99_RS16360	COG1056	cytidyltransferase-related domain
FDM99_RS16365	COG1024	Enoyl-CoA hydratase
FDM99_RS16375	COG2814	Major facilitator Superfamily
FDM99_RS16380	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FDM99_RS16380	COG0047	phosphoribosylformylglycinamidine synthase activity
FDM99_RS16400	COG1473	amidohydrolase
FDM99_RS16405	COG0824	Thioesterase
FDM99_RS16425	COG0823	Involved in the tonB-independent uptake of proteins
FDM99_RS16445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDM99_RS16475	COG0628	permease
FDM99_RS16485	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDM99_RS16490	COG0596	Alpha beta hydrolase
FDM99_RS16495	COG0616	signal peptide processing
FDM99_RS16495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDM99_RS16510	COG1136	(ABC) transporter
FDM99_RS16515	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDM99_RS16545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDM99_RS16565	COG0463	Glycosyl transferase, family 2
FDM99_RS16595	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDM99_RS16600	COG1280	lysine exporter protein (LysE YggA)
FDM99_RS16610	COG0019	diaminopimelate decarboxylase activity
FDM99_RS16620	COG1113	amino acid transport
FDM99_RS16635	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FDM99_RS16645	COG3339	Conserved Protein
FDM99_RS16650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDM99_RS16655	COG0243	molybdopterin cofactor binding
FDM99_RS16660	COG1929	Belongs to the glycerate kinase type-1 family
FDM99_RS16675	COG0778	Nitroreductase
FDM99_RS16705	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDM99_RS16740	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDM99_RS16775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDM99_RS16800	COG0741	lytic transglycosylase activity
FDM99_RS16820	COG0584	glycerophosphoryl diester phosphodiesterase
FDM99_RS16855	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDM99_RS16860	COG1597	lipid kinase activity
FDM99_RS16875	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FDM99_RS16880	COG0477	Major facilitator Superfamily
FDM99_RS16930	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDM99_RS16935	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDM99_RS16960	COG0505	Belongs to the CarA family
FDM99_RS16980	COG0589	response to stress
FDM99_RS17015	COG2321	neutral zinc metallopeptidase
FDM99_RS17020	COG2354	Protein conserved in bacteria
FDM99_RS17040	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDM99_RS17065	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDM99_RS17070	COG1053	succinate dehydrogenase
FDM99_RS17075	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FDM99_RS17080	COG2009	succinate dehydrogenase
FDM99_RS17115	COG2921	Belongs to the UPF0250 family
FDM99_RS17120	COG0321	lipoyl(octanoyl) transferase activity
FDM99_RS17135	COG0531	amino acid
FDM99_RS17145	COG1733	regulation of RNA biosynthetic process
FDM99_RS17150	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FDM99_RS17155	COG1648	precorrin-2 dehydrogenase activity
FDM99_RS17155	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDM99_RS17170	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FDM99_RS17200	COG0671	phosphoesterase, PA-phosphatase related
FDM99_RS17205	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDM99_RS17215	COG1538	Outer membrane efflux protein
FDM99_RS17220	COG0393	Putative heavy-metal-binding
FDM99_RS17225	COG0393	Putative heavy-metal-binding
FDM99_RS17235	COG1028	Short-chain dehydrogenase reductase Sdr
FDM99_RS17245	COG0525	valine-tRNA ligase activity
FDM99_RS17265	COG0583	DNA-binding transcription factor activity
FDM99_RS17275	COG0004	ammonium transporteR
FDM99_RS17285	COG0642	Histidine kinase
FDM99_RS17290	COG0745	RESPONSE REGULATOR receiver
FDM99_RS17295	COG2194	sulfuric ester hydrolase activity
FDM99_RS17315	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDM99_RS17330	COG2315	Protein conserved in bacteria
FDM99_RS17335	COG0142	geranyltranstransferase activity
FDM99_RS17340	COG2828	Protein conserved in bacteria
FDM99_RS17345	COG1113	amino acid transport
FDM99_RS17395	COG2207	Transcriptional regulator
FDM99_RS17420	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDM99_RS17430	COG0560	Phosphoserine phosphatase
FDM99_RS17445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDM99_RS17455	COG1530	ribonuclease E activity
FDM99_RS17460	COG0424	maF-like protein
FDM99_RS17465	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FDM99_RS17470	COG1792	Involved in formation and maintenance of cell shape
FDM99_RS17475	COG1077	Cell shape determining protein MreB Mrl
FDM99_RS17480	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDM99_RS17490	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDM99_RS17515	COG3590	peptidase
FDM99_RS17520	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FDM99_RS17525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDM99_RS17530	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDM99_RS17535	COG1115	amino acid carrier protein
FDM99_RS17555	COG2814	Major facilitator Superfamily
FDM99_RS17560	COG1289	transmembrane transporter activity
FDM99_RS17570	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FDM99_RS17610	COG1376	ErfK ybiS ycfS ynhG family protein
FDM99_RS17615	COG2832	Protein of unknown function (DUF454)
FDM99_RS17625	COG5510	response to toxic substance
FDM99_RS17650	COG0840	transmembrane signaling receptor activity
FDM99_RS17690	COG3422	double-strand break repair
FDM99_RS17695	COG2824	Alkylphosphonate utilization operon protein PhnA
FDM99_RS17700	COG3189	MarR family transcriptional regulator
FDM99_RS17710	COG0354	folic acid binding
FDM99_RS17715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDM99_RS17725	COG0679	Auxin Efflux Carrier
FDM99_RS17730	COG1902	pentaerythritol trinitrate reductase activity
FDM99_RS17735	COG4772	TonB-dependent receptor
FDM99_RS17740	COG2094	Belongs to the DNA glycosylase MPG family
FDM99_RS17765	COG1217	gtp-binding protein TYPA
FDM99_RS17770	COG2233	PERMEase
FDM99_RS17780	COG0833	amino acid
FDM99_RS17785	COG1690	Belongs to the RtcB family
FDM99_RS17790	COG2885	chlorophyll binding
FDM99_RS17790	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FDM99_RS17800	COG0183	Belongs to the thiolase family
FDM99_RS17820	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDM99_RS17840	COG2207	Transcriptional regulator
FDM99_RS17845	COG0183	Belongs to the thiolase family
FDM99_RS17875	COG1272	protein, Hemolysin III
FDM99_RS17880	COG0477	Major facilitator Superfamily
FDM99_RS17895	COG0450	alkyl hydroperoxide reductase
FDM99_RS17915	COG0285	dihydrofolate synthase activity
FDM99_RS17960	COG4206	TonB-dependent receptor
FDM99_RS17965	COG2096	Adenosyltransferase
FDM99_RS17970	COG0584	glycerophosphoryl diester phosphodiesterase
FDM99_RS17985	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FDM99_RS17990	COG0745	RESPONSE REGULATOR receiver
FDM99_RS17995	COG2205	protein histidine kinase activity
FDM99_RS18005	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS18010	COG1960	acyl-CoA dehydrogenase activity
FDM99_RS18070	COG0438	transferase activity, transferring glycosyl groups
FDM99_RS18075	COG0463	Glycosyl transferase, family 2
FDM99_RS18080	COG0726	polysaccharide deacetylase
FDM99_RS18100	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FDM99_RS18105	COG2205	protein histidine kinase activity
FDM99_RS18140	COG1862	Preprotein translocase
FDM99_RS18150	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDM99_RS18155	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FDM99_RS18165	COG3781	membrane
FDM99_RS18170	COG0613	PHP domain protein
FDM99_RS18180	COG2350	Protein conserved in bacteria
FDM99_RS18230	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FDM99_RS18280	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
FDM99_RS18360	COG4683	PFAM Phage derived protein Gp49-like (DUF891)