locus-tag	class	description
EA674_RS00010	COG0592	DNA-directed DNA polymerase activity
EA674_RS00020	COG0187	DNA topoisomerase II activity
EA674_RS00030	COG0586	Pfam SNARE associated Golgi protein
EA674_RS00035	COG0488	(ABC) transporter
EA674_RS00060	COG0596	Alpha beta hydrolase
EA674_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EA674_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EA674_RS00115	COG0733	neurotransmitter:sodium symporter activity
EA674_RS00155	COG2233	PERMEase
EA674_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA674_RS00205	COG2814	Major facilitator Superfamily
EA674_RS00210	COG0656	L-ascorbic acid biosynthetic process
EA674_RS00215	COG0583	DNA-binding transcription factor activity
EA674_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA674_RS00235	COG1064	alcohol dehydrogenase
EA674_RS00240	COG2818	Glycosylase
EA674_RS00255	COG1194	a g-specific adenine glycosylase
EA674_RS00275	COG2983	Belongs to the UPF0260 family
EA674_RS00280	COG2133	pyrroloquinoline quinone binding
EA674_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EA674_RS00290	COG2116	formate transmembrane transporter activity
EA674_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA674_RS00315	COG1335	isochorismatase
EA674_RS00320	COG0385	Bile acid
EA674_RS00325	COG0534	Mate efflux family protein
EA674_RS00330	COG1683	Conserved Protein
EA674_RS00350	COG0625	glutathione transferase activity
EA674_RS00360	COG1113	amino acid transport
EA674_RS00370	COG0523	cobalamin synthesis protein
EA674_RS00380	COG2188	Transcriptional regulator
EA674_RS00410	COG0010	Belongs to the arginase family
EA674_RS00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA674_RS00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EA674_RS00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EA674_RS00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EA674_RS00555	COG0534	Mate efflux family protein
EA674_RS00560	COG0436	Aminotransferase
EA674_RS00565	COG2733	membrane
EA674_RS00580	COG2918	glutathione biosynthetic process
EA674_RS00595	COG0791	NLP P60 protein
EA674_RS00595	COG1388	LysM domain
EA674_RS00615	COG3150	esterase
EA674_RS00625	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EA674_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA674_RS00650	COG2233	PERMEase
EA674_RS00655	COG2351	hydroxyisourate hydrolase activity
EA674_RS00690	COG3706	GGDEF domain
EA674_RS00705	COG1393	Belongs to the ArsC family
EA674_RS00710	COG0708	Exodeoxyribonuclease III
EA674_RS00730	COG0189	ligase activity
EA674_RS00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EA674_RS00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EA674_RS00775	COG4942	peptidase
EA674_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA674_RS00795	COG2119	membrane
EA674_RS00800	COG4774	siderophore transport
EA674_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA674_RS00805	COG0426	domain, Protein
EA674_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EA674_RS00850	COG1902	pentaerythritol trinitrate reductase activity
EA674_RS00855	COG1519	Transferase
EA674_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA674_RS00865	COG0668	transmembrane transport
EA674_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA674_RS00880	COG1335	isochorismatase
EA674_RS00885	COG1522	sequence-specific DNA binding
EA674_RS00890	COG3328	transposase activity
EA674_RS00915	COG2205	protein histidine kinase activity
EA674_RS00915	COG0784	Response regulator, receiver
EA674_RS00915	COG2198	Histidine kinase
EA674_RS00920	COG3162	membrane
EA674_RS00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA674_RS00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA674_RS00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EA674_RS00960	COG1309	transcriptional regulator
EA674_RS00980	COG0352	thiamine-phosphate diphosphorylase activity
EA674_RS00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA674_RS00980	COG0351	phosphomethylpyrimidine kinase
EA674_RS00990	COG2814	Major facilitator Superfamily
EA674_RS01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA674_RS01015	COG1113	amino acid transport
EA674_RS01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA674_RS01030	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS01040	COG1335	isochorismatase
EA674_RS01070	COG2814	Major facilitator Superfamily
EA674_RS01075	COG0583	DNA-binding transcription factor activity
EA674_RS01095	COG0667	Aldo Keto reductase
EA674_RS01130	COG1733	regulation of RNA biosynthetic process
EA674_RS01140	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA674_RS01205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EA674_RS01220	COG2329	Antibiotic biosynthesis monooxygenase
EA674_RS01250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EA674_RS01280	COG0427	acetyl-CoA hydrolase
EA674_RS01305	COG0659	secondary active sulfate transmembrane transporter activity
EA674_RS01310	COG4221	oxidoreductase activity
EA674_RS01315	COG2873	o-acetylhomoserine
EA674_RS01320	COG0488	(ABC) transporter
EA674_RS01405	COG0833	amino acid
EA674_RS01450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EA674_RS01455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EA674_RS01470	COG2226	methyltransferase
EA674_RS01520	COG0070	glutamate synthase
EA674_RS01520	COG0067	glutamate synthase
EA674_RS01520	COG0069	glutamate synthase activity
EA674_RS01525	COG0493	'glutamate synthase
EA674_RS01535	COG1704	LemA family
EA674_RS01540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EA674_RS01550	COG4969	Belongs to the N-Me-Phe pilin family
EA674_RS01555	COG3307	-O-antigen
EA674_RS01575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA674_RS01590	COG0194	GDP metabolic process
EA674_RS01640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EA674_RS01660	COG5380	lipid catabolic process
EA674_RS01665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EA674_RS01690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EA674_RS01695	COG0277	FAD linked oxidase domain protein
EA674_RS01705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EA674_RS01710	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA674_RS01725	COG1289	transmembrane transporter activity
EA674_RS01735	COG0628	permease
EA674_RS01740	COG1192	Involved in chromosome partitioning
EA674_RS01770	COG0833	amino acid
EA674_RS01775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EA674_RS01780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA674_RS01790	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS01830	COG0583	DNA-binding transcription factor activity
EA674_RS01875	COG0517	IMP dehydrogenase activity
EA674_RS01880	COG1983	PspC domain protein
EA674_RS01890	COG1960	acyl-CoA dehydrogenase activity
EA674_RS01905	COG0408	coproporphyrinogen oxidase activity
EA674_RS01925	COG0513	Belongs to the DEAD box helicase family
EA674_RS01935	COG1127	ABC transporter
EA674_RS01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EA674_RS01950	COG2854	intermembrane phospholipid transfer
EA674_RS01960	COG0598	Magnesium transport protein CorA
EA674_RS01970	COG0494	nUDIX hydrolase
EA674_RS01975	COG1040	competence protein
EA674_RS01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EA674_RS02000	COG1946	Acyl-CoA thioesterase
EA674_RS02005	COG1301	dicarboxylic acid transport
EA674_RS02020	COG1959	2 iron, 2 sulfur cluster binding
EA674_RS02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA674_RS02025	COG1017	nitric oxide dioxygenase activity
EA674_RS02030	COG0433	COG0433 Predicted ATPase
EA674_RS02035	COG0626	cystathionine gamma-synthase activity
EA674_RS02190	COG1960	acyl-CoA dehydrogenase activity
EA674_RS02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EA674_RS02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EA674_RS02230	COG0339	signal peptide processing
EA674_RS02235	COG0557	exoribonuclease II activity
EA674_RS02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
EA674_RS02285	COG2169	Transcriptional regulator
EA674_RS02290	COG0697	spore germination
EA674_RS02295	COG1295	ribonuclease BN
EA674_RS02330	COG1702	phosphate starvation-inducible protein PhoH
EA674_RS02340	COG0739	heme binding
EA674_RS02340	COG0741	lytic transglycosylase activity
EA674_RS02340	COG1196	nuclear chromosome segregation
EA674_RS02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EA674_RS02375	COG1183	phosphatidylcholine synthase activity
EA674_RS02420	COG1960	acyl-CoA dehydrogenase activity
EA674_RS02425	COG1309	transcriptional regulator
EA674_RS02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA674_RS02445	COG1960	acyl-CoA dehydrogenase activity
EA674_RS02465	COG2969	positive regulation of protein catabolic process
EA674_RS02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EA674_RS02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EA674_RS02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EA674_RS02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EA674_RS02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EA674_RS02530	COG1408	metallophosphoesterase
EA674_RS02540	COG2199	diguanylate cyclase activity
EA674_RS02600	COG1607	acyl-coa hydrolase
EA674_RS02630	COG2350	Protein conserved in bacteria
EA674_RS02640	COG0613	PHP domain protein
EA674_RS02645	COG3781	membrane
EA674_RS02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EA674_RS02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EA674_RS02670	COG1862	Preprotein translocase
EA674_RS02720	COG2205	protein histidine kinase activity
EA674_RS02725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EA674_RS02745	COG0726	polysaccharide deacetylase
EA674_RS02750	COG0463	Glycosyl transferase, family 2
EA674_RS02755	COG0438	transferase activity, transferring glycosyl groups
EA674_RS02820	COG0625	glutathione transferase activity
EA674_RS02825	COG0583	DNA-binding transcription factor activity
EA674_RS02830	COG1960	acyl-CoA dehydrogenase activity
EA674_RS02835	COG1960	acyl-CoA dehydrogenase activity
EA674_RS02845	COG2205	protein histidine kinase activity
EA674_RS02850	COG0745	RESPONSE REGULATOR receiver
EA674_RS02855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EA674_RS02875	COG2096	Adenosyltransferase
EA674_RS02925	COG0285	dihydrofolate synthase activity
EA674_RS02945	COG0450	alkyl hydroperoxide reductase
EA674_RS02960	COG0477	Major facilitator Superfamily
EA674_RS02965	COG1272	protein, Hemolysin III
EA674_RS02995	COG0183	Belongs to the thiolase family
EA674_RS03000	COG2207	Transcriptional regulator
EA674_RS03020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA674_RS03040	COG0183	Belongs to the thiolase family
EA674_RS03050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EA674_RS03050	COG2885	chlorophyll binding
EA674_RS03060	COG1690	Belongs to the RtcB family
EA674_RS03065	COG0833	amino acid
EA674_RS03075	COG2233	PERMEase
EA674_RS03080	COG1217	gtp-binding protein TYPA
EA674_RS03105	COG2094	Belongs to the DNA glycosylase MPG family
EA674_RS03110	COG4772	TonB-dependent receptor
EA674_RS03115	COG1902	pentaerythritol trinitrate reductase activity
EA674_RS03120	COG0679	Auxin Efflux Carrier
EA674_RS03130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA674_RS03135	COG0354	folic acid binding
EA674_RS03145	COG3189	MarR family transcriptional regulator
EA674_RS03150	COG2824	Alkylphosphonate utilization operon protein PhnA
EA674_RS03155	COG3422	double-strand break repair
EA674_RS03195	COG0840	transmembrane signaling receptor activity
EA674_RS03215	COG5510	response to toxic substance
EA674_RS03225	COG2832	Protein of unknown function (DUF454)
EA674_RS03230	COG1376	ErfK ybiS ycfS ynhG family protein
EA674_RS03270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EA674_RS03280	COG1289	transmembrane transporter activity
EA674_RS03285	COG2814	Major facilitator Superfamily
EA674_RS03305	COG1115	amino acid carrier protein
EA674_RS03310	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA674_RS03315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA674_RS03320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EA674_RS03350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA674_RS03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA674_RS03365	COG1077	Cell shape determining protein MreB Mrl
EA674_RS03370	COG1792	Involved in formation and maintenance of cell shape
EA674_RS03375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EA674_RS03380	COG0424	maF-like protein
EA674_RS03385	COG1530	ribonuclease E activity
EA674_RS03395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA674_RS03405	COG0560	Phosphoserine phosphatase
EA674_RS03415	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA674_RS03440	COG2207	Transcriptional regulator
EA674_RS03460	COG1113	amino acid transport
EA674_RS03465	COG2828	Protein conserved in bacteria
EA674_RS03470	COG0142	geranyltranstransferase activity
EA674_RS03475	COG2315	Protein conserved in bacteria
EA674_RS03490	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA674_RS03515	COG2194	sulfuric ester hydrolase activity
EA674_RS03520	COG0745	RESPONSE REGULATOR receiver
EA674_RS03525	COG0642	Histidine kinase
EA674_RS03535	COG0004	ammonium transporteR
EA674_RS03545	COG0583	DNA-binding transcription factor activity
EA674_RS03565	COG0525	valine-tRNA ligase activity
EA674_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS03585	COG0393	Putative heavy-metal-binding
EA674_RS03590	COG0393	Putative heavy-metal-binding
EA674_RS03595	COG1538	Outer membrane efflux protein
EA674_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA674_RS03610	COG0671	phosphoesterase, PA-phosphatase related
EA674_RS03640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EA674_RS03655	COG1648	precorrin-2 dehydrogenase activity
EA674_RS03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EA674_RS03660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EA674_RS03665	COG1733	regulation of RNA biosynthetic process
EA674_RS03675	COG0531	amino acid
EA674_RS03690	COG0321	lipoyl(octanoyl) transferase activity
EA674_RS03695	COG2921	Belongs to the UPF0250 family
EA674_RS03735	COG2009	succinate dehydrogenase
EA674_RS03740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EA674_RS03745	COG1053	succinate dehydrogenase
EA674_RS03750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EA674_RS03775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA674_RS03795	COG2354	Protein conserved in bacteria
EA674_RS03800	COG2321	neutral zinc metallopeptidase
EA674_RS03850	COG2843	Capsule synthesis protein
EA674_RS03865	COG0589	response to stress
EA674_RS03885	COG0505	Belongs to the CarA family
EA674_RS03910	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA674_RS03915	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EA674_RS03965	COG0477	Major facilitator Superfamily
EA674_RS03970	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EA674_RS03985	COG1597	lipid kinase activity
EA674_RS03990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA674_RS04015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA674_RS04020	COG0584	glycerophosphoryl diester phosphodiesterase
EA674_RS04040	COG0741	lytic transglycosylase activity
EA674_RS04065	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EA674_RS04080	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA674_RS04110	COG0778	Nitroreductase
EA674_RS04125	COG1929	Belongs to the glycerate kinase type-1 family
EA674_RS04130	COG0243	molybdopterin cofactor binding
EA674_RS04135	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EA674_RS04140	COG3339	Conserved Protein
EA674_RS04150	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EA674_RS04165	COG1113	amino acid transport
EA674_RS04175	COG0019	diaminopimelate decarboxylase activity
EA674_RS04185	COG1280	lysine exporter protein (LysE YggA)
EA674_RS04190	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EA674_RS04220	COG0463	Glycosyl transferase, family 2
EA674_RS04240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA674_RS04270	COG4591	ABC-type transport system involved in lipoprotein release permease component
EA674_RS04275	COG1136	(ABC) transporter
EA674_RS04280	COG0658	competence protein
EA674_RS04280	COG2333	competence protein COMEC
EA674_RS04290	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EA674_RS04290	COG0616	signal peptide processing
EA674_RS04295	COG0596	Alpha beta hydrolase
EA674_RS04300	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EA674_RS04310	COG0628	permease
EA674_RS04345	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA674_RS04365	COG0823	Involved in the tonB-independent uptake of proteins
EA674_RS04385	COG0824	Thioesterase
EA674_RS04390	COG1473	amidohydrolase
EA674_RS04410	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EA674_RS04410	COG0047	phosphoribosylformylglycinamidine synthase activity
EA674_RS04415	COG2814	Major facilitator Superfamily
EA674_RS04425	COG1024	Enoyl-CoA hydratase
EA674_RS04430	COG1051	belongs to the nudix hydrolase family
EA674_RS04430	COG1056	cytidyltransferase-related domain
EA674_RS04440	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EA674_RS04455	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EA674_RS04470	COG4625	pathogenesis
EA674_RS04475	COG0583	DNA-binding transcription factor activity
EA674_RS04480	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EA674_RS04485	COG4208	sulfate ABC transporter
EA674_RS04490	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EA674_RS04500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EA674_RS04505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EA674_RS04510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EA674_RS04530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA674_RS04545	COG0681	Belongs to the peptidase S26 family
EA674_RS04560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EA674_RS04570	COG1381	Involved in DNA repair and RecF pathway recombination
EA674_RS04575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EA674_RS04585	COG4221	oxidoreductase activity
EA674_RS04615	COG0436	Aminotransferase
EA674_RS04635	COG0556	nucleotide-excision repair
EA674_RS04830	COG5410	chromosome segregation
EA674_RS05025	COG2070	2-Nitropropane dioxygenase
EA674_RS05055	COG1215	transferase activity, transferring glycosyl groups
EA674_RS05070	COG0415	Belongs to the DNA photolyase family
EA674_RS05080	COG1252	NADH dehydrogenase
EA674_RS05100	COG1187	pseudouridine synthase activity
EA674_RS05125	COG0477	Major facilitator Superfamily
EA674_RS05130	COG0583	DNA-binding transcription factor activity
EA674_RS05135	COG1823	symporter activity
EA674_RS05145	COG0612	Peptidase, M16
EA674_RS05170	COG0352	thiamine-phosphate diphosphorylase activity
EA674_RS05205	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA674_RS05220	COG1309	transcriptional regulator
EA674_RS05230	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA674_RS05235	COG0076	glutamate decarboxylase activity
EA674_RS05245	COG1522	sequence-specific DNA binding
EA674_RS05250	COG3961	Belongs to the TPP enzyme family
EA674_RS05255	COG1113	amino acid transport
EA674_RS05260	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EA674_RS05265	COG0573	inorganic phosphate transmembrane transporter activity
EA674_RS05275	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EA674_RS05280	COG0616	signal peptide processing
EA674_RS05315	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EA674_RS05320	COG1686	Belongs to the peptidase S11 family
EA674_RS05345	COG0583	DNA-binding transcription factor activity
EA674_RS05350	COG1067	ATP-dependent peptidase activity
EA674_RS05395	COG1966	Carbon starvation protein
EA674_RS05400	COG2879	small protein
EA674_RS05435	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EA674_RS05435	COG2508	Transcriptional regulator
EA674_RS05455	COG1113	amino acid transport
EA674_RS05460	COG0583	DNA-binding transcription factor activity
EA674_RS05465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA674_RS05470	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA674_RS05480	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS05485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA674_RS05490	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA674_RS05490	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EA674_RS05525	COG2814	Major facilitator Superfamily
EA674_RS05530	COG4948	Mandelate Racemase Muconate Lactonizing
EA674_RS05540	COG1309	transcriptional regulator
EA674_RS05560	COG1741	Belongs to the pirin family
EA674_RS05570	COG2964	Protein conserved in bacteria
EA674_RS05585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA674_RS05590	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EA674_RS05595	COG4605	iron ion homeostasis
EA674_RS05600	COG4604	ABC transporter, ATP-binding protein
EA674_RS05605	COG4607	ABC-type enterochelin transport system periplasmic component
EA674_RS05615	COG4774	siderophore transport
EA674_RS05625	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA674_RS05630	COG1021	2,3-dihydroxybenzoate-AMP ligase
EA674_RS05635	COG1535	isochorismatase
EA674_RS05635	COG3433	isochorismatase activity
EA674_RS05650	COG1132	(ABC) transporter
EA674_RS05655	COG1132	(ABC) transporter
EA674_RS05660	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EA674_RS05670	COG1169	isochorismate synthase
EA674_RS05685	COG3739	integral membrane protein
EA674_RS05705	COG0302	gtp cyclohydrolase
EA674_RS05715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EA674_RS05745	COG0308	aminopeptidase N
EA674_RS05750	COG0512	Glutamine amidotransferase of anthranilate synthase
EA674_RS05880	COG5410	chromosome segregation
EA674_RS06070	COG0582	viral genome integration into host DNA
EA674_RS06085	COG0174	glutamine synthetase
EA674_RS06095	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EA674_RS06130	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EA674_RS06135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EA674_RS06140	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA674_RS06160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA674_RS06165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EA674_RS06170	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EA674_RS06185	COG1960	acyl-CoA dehydrogenase activity
EA674_RS06190	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA674_RS06195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA674_RS06205	COG2223	nitrite transmembrane transporter activity
EA674_RS06215	COG0024	Methionine aminopeptidase
EA674_RS06220	COG0052	Belongs to the universal ribosomal protein uS2 family
EA674_RS06235	COG2207	Transcriptional regulator
EA674_RS06260	COG2951	lytic endotransglycosylase activity
EA674_RS06265	COG0772	Belongs to the SEDS family
EA674_RS06280	COG0842	Transport permease protein
EA674_RS06285	COG1131	(ABC) transporter
EA674_RS06330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA674_RS06355	COG4215	(ABC) transporter
EA674_RS06360	COG4160	amino acid transport
EA674_RS06365	COG4598	ABC transporter
EA674_RS06375	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA674_RS06380	COG0826	peptidase U32
EA674_RS06385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA674_RS06400	COG1720	tRNA m6t6A37 methyltransferase activity
EA674_RS06410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EA674_RS06425	COG0642	Histidine kinase
EA674_RS06435	COG0494	nUDIX hydrolase
EA674_RS06445	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EA674_RS06450	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EA674_RS06455	COG3139	Protein of unknown function (DUF1315)
EA674_RS06460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EA674_RS06470	COG1301	dicarboxylic acid transport
EA674_RS06475	COG1960	acyl-CoA dehydrogenase activity
EA674_RS06480	COG2819	hydrolase of the alpha beta superfamily
EA674_RS06490	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EA674_RS06500	COG2195	Cleaves the N-terminal amino acid of tripeptides
EA674_RS06505	COG1234	tRNA 3'-trailer cleavage
EA674_RS06535	COG2363	Small membrane protein
EA674_RS06555	COG0513	Belongs to the DEAD box helicase family
EA674_RS06565	COG0778	Nitroreductase
EA674_RS06595	COG1286	toxin biosynthetic process
EA674_RS06620	COG4783	chaperone-mediated protein folding
EA674_RS06625	COG1610	YqeY-like protein
EA674_RS06725	COG3111	PFAM Bacterial OB fold (BOF) protein
EA674_RS06750	COG3243	poly(R)-hydroxyalkanoic acid synthase
EA674_RS06755	COG0786	glutamate:sodium symporter activity
EA674_RS06765	COG2186	Transcriptional regulator
EA674_RS06815	COG0477	Major facilitator Superfamily
EA674_RS06845	COG2985	domain, Protein
EA674_RS06855	COG2995	paraquat-inducible protein a
EA674_RS06860	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EA674_RS06860	COG3008	intermembrane lipid transfer
EA674_RS06870	COG1794	racemase activity, acting on amino acids and derivatives
EA674_RS06900	COG1301	dicarboxylic acid transport
EA674_RS06910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA674_RS06915	COG2011	ABC-type metal ion transport system permease component
EA674_RS06920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA674_RS06925	COG1464	Belongs to the NlpA lipoprotein family
EA674_RS06930	COG0151	Belongs to the GarS family
EA674_RS06935	COG0138	bifunctional purine biosynthesis protein purh
EA674_RS06940	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EA674_RS06970	COG2308	Evidence 4 Homologs of previously reported genes of
EA674_RS06980	COG1305	Transglutaminase-like
EA674_RS06990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EA674_RS06995	COG0305	Participates in initiation and elongation during chromosome replication
EA674_RS07020	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EA674_RS07030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EA674_RS07035	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EA674_RS07060	COG1649	PFAM Uncharacterised BCR, COG1649
EA674_RS07060	COG0726	polysaccharide deacetylase
EA674_RS07065	COG1215	transferase activity, transferring glycosyl groups
EA674_RS07070	COG3658	cytochrome
EA674_RS07080	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA674_RS07100	COG0583	DNA-binding transcription factor activity
EA674_RS07120	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA674_RS07125	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA674_RS07140	COG1960	acyl-CoA dehydrogenase activity
EA674_RS07145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA674_RS07150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA674_RS07175	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EA674_RS07180	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EA674_RS07190	COG2205	protein histidine kinase activity
EA674_RS07195	COG0745	RESPONSE REGULATOR receiver
EA674_RS07200	COG0174	glutamine synthetase
EA674_RS07220	COG0729	surface antigen
EA674_RS07250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA674_RS07255	COG2814	Major facilitator Superfamily
EA674_RS07270	COG0583	DNA-binding transcription factor activity
EA674_RS07285	COG1187	pseudouridine synthase activity
EA674_RS07305	COG0802	atpase or kinase
EA674_RS07310	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EA674_RS07320	COG1923	regulation of RNA biosynthetic process
EA674_RS07325	COG0697	spore germination
EA674_RS07340	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA674_RS07350	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA674_RS07355	COG0519	Catalyzes the synthesis of GMP from XMP
EA674_RS07355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA674_RS07360	COG4302	ethanolamine ammonia-lyase activity
EA674_RS07365	COG4303	Ethanolamine ammonia lyase large subunit
EA674_RS07370	COG0531	amino acid
EA674_RS07390	COG1454	alcohol dehydrogenase
EA674_RS07395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA674_RS07405	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EA674_RS07425	COG0308	aminopeptidase N
EA674_RS07435	COG4221	oxidoreductase activity
EA674_RS07445	COG1605	Chorismate mutase
EA674_RS07465	COG1309	transcriptional regulator
EA674_RS07475	COG0668	transmembrane transport
EA674_RS07505	COG4773	Receptor
EA674_RS07525	COG0488	(ABC) transporter
EA674_RS07530	COG0589	response to stress
EA674_RS07545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EA674_RS07555	COG3135	benzoate transporter
EA674_RS07560	COG1522	sequence-specific DNA binding
EA674_RS07570	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EA674_RS07575	COG0583	DNA-binding transcription factor activity
EA674_RS07585	COG0183	Belongs to the thiolase family
EA674_RS07595	COG2030	dehydratase
EA674_RS07600	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EA674_RS07615	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EA674_RS07625	COG0824	Thioesterase
EA674_RS07630	COG1454	alcohol dehydrogenase
EA674_RS07640	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EA674_RS07660	COG0069	glutamate synthase activity
EA674_RS07830	COG5410	chromosome segregation
EA674_RS08030	COG2814	Major facilitator Superfamily
EA674_RS08045	COG0511	ligase activity, forming carbon-carbon bonds
EA674_RS08065	COG1116	anion transmembrane transporter activity
EA674_RS08065	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA674_RS08070	COG0745	RESPONSE REGULATOR receiver
EA674_RS08080	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA674_RS08080	COG2146	nitrite reductase [NAD(P)H] activity
EA674_RS08085	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA674_RS08090	COG0243	molybdopterin cofactor binding
EA674_RS08100	COG0243	molybdopterin cofactor binding
EA674_RS08105	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EA674_RS08120	COG0521	Mo-molybdopterin cofactor biosynthetic process
EA674_RS08120	COG0315	cyclic pyranopterin monophosphate synthase activity
EA674_RS08125	COG0303	'Molybdopterin
EA674_RS08135	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA674_RS08140	COG0697	spore germination
EA674_RS08160	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EA674_RS08165	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA674_RS08225	COG2204	response regulator
EA674_RS08230	COG3852	Histidine kinase
EA674_RS08255	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EA674_RS08260	COG0575	Belongs to the CDS family
EA674_RS08295	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA674_RS08310	COG2137	regulation of response to DNA damage stimulus
EA674_RS08320	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EA674_RS08325	COG1011	Hydrolase
EA674_RS08350	COG1522	sequence-specific DNA binding
EA674_RS08360	COG1113	amino acid transport
EA674_RS08375	COG0659	secondary active sulfate transmembrane transporter activity
EA674_RS08410	COG1132	(ABC) transporter
EA674_RS08460	COG0482	sulfurtransferase activity
EA674_RS08475	COG0488	(ABC) transporter
EA674_RS08480	COG3173	Aminoglycoside phosphotransferase
EA674_RS08490	COG2433	Pfam Transposase IS66
EA674_RS08535	COG5001	Diguanylate cyclase
EA674_RS08535	COG3300	MHYT domain
EA674_RS08555	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA674_RS08555	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EA674_RS08555	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA674_RS08560	COG1105	Belongs to the carbohydrate kinase PfkB family
EA674_RS08565	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EA674_RS08565	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA674_RS08595	COG0024	Methionine aminopeptidase
EA674_RS08600	COG0583	DNA-binding transcription factor activity
EA674_RS08610	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EA674_RS08615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA674_RS08620	COG0517	IMP dehydrogenase activity
EA674_RS08620	COG0516	GMP reductase activity
EA674_RS08645	COG0552	protein localization to endoplasmic reticulum
EA674_RS08655	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EA674_RS08670	COG4890	Cyd operon protein YbgT
EA674_RS08675	COG1294	oxidase, subunit
EA674_RS08695	COG1585	Membrane protein implicated in regulation of membrane protease activity
EA674_RS08705	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EA674_RS08710	COG4774	siderophore transport
EA674_RS08725	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EA674_RS08730	COG0569	domain protein
EA674_RS08735	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA674_RS08765	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EA674_RS08770	COG0542	response to heat
EA674_RS08795	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA674_RS08795	COG1902	pentaerythritol trinitrate reductase activity
EA674_RS08840	COG2323	membrane
EA674_RS08845	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EA674_RS08855	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA674_RS08860	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA674_RS08865	COG0183	Belongs to the thiolase family
EA674_RS08870	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EA674_RS08875	COG0596	Alpha beta hydrolase
EA674_RS08880	COG2271	Major facilitator Superfamily
EA674_RS08885	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA674_RS08890	COG3485	protocatechuate 3,4-dioxygenase
EA674_RS08895	COG3485	protocatechuate 3,4-dioxygenase
EA674_RS08900	COG0710	3-dehydroquinate dehydratase activity
EA674_RS08905	COG3420	alginic acid biosynthetic process
EA674_RS08910	COG3659	wide pore channel activity
EA674_RS08915	COG4993	Dehydrogenase
EA674_RS08925	COG2391	methyltransferase activity
EA674_RS08940	COG1414	Transcriptional regulator
EA674_RS08945	COG0583	DNA-binding transcription factor activity
EA674_RS08950	COG1960	acyl-CoA dehydrogenase activity
EA674_RS08975	COG2814	Major facilitator Superfamily
EA674_RS08985	COG0154	amidase activity
EA674_RS09005	COG4638	Rieske (2fe-2S)
EA674_RS09015	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS09025	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA674_RS09035	COG3733	amine oxidase
EA674_RS09045	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS09055	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA674_RS09060	COG0183	Belongs to the thiolase family
EA674_RS09065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA674_RS09070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA674_RS09080	COG4829	muconolactone delta-isomerase
EA674_RS09085	COG4948	Mandelate Racemase Muconate Lactonizing
EA674_RS09090	COG0583	DNA-binding transcription factor activity
EA674_RS09100	COG2186	Transcriptional regulator
EA674_RS09120	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS09140	COG1960	acyl-CoA dehydrogenase activity
EA674_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS09150	COG3829	transcription factor binding
EA674_RS09160	COG3162	membrane
EA674_RS09175	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS09190	COG0753	catalase activity
EA674_RS09215	COG1846	Transcriptional regulator
EA674_RS09220	COG1902	pentaerythritol trinitrate reductase activity
EA674_RS09220	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA674_RS09230	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EA674_RS09260	COG1309	transcriptional regulator
EA674_RS09270	COG1335	isochorismatase
EA674_RS09280	COG0583	DNA-binding transcription factor activity
EA674_RS09290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA674_RS09290	COG0475	glutathione-regulated potassium exporter activity
EA674_RS09300	COG1473	amidohydrolase
EA674_RS09320	COG2831	hemolysin activation secretion protein
EA674_RS09325	COG3210	domain, Protein
EA674_RS09355	COG2188	Transcriptional regulator
EA674_RS09370	COG0583	DNA-binding transcription factor activity
EA674_RS09400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA674_RS09420	COG1566	PFAM secretion protein HlyD family protein
EA674_RS09435	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS09440	COG0129	dihydroxy-acid dehydratase activity
EA674_RS09450	COG0583	DNA-binding transcription factor activity
EA674_RS09455	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EA674_RS09465	COG2084	Dehydrogenase
EA674_RS09470	COG2207	Transcriptional regulator
EA674_RS09485	COG1064	alcohol dehydrogenase
EA674_RS09495	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EA674_RS09500	COG1120	ATPase activity
EA674_RS09520	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA674_RS09640	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EA674_RS09695	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS09710	COG2207	Transcriptional regulator
EA674_RS09725	COG0745	RESPONSE REGULATOR receiver
EA674_RS09730	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA674_RS09735	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA674_RS09740	COG1538	Outer membrane efflux protein
EA674_RS09750	COG2072	flavoprotein involved in K transport
EA674_RS09770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA674_RS09790	COG3539	Fimbrial protein
EA674_RS09820	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EA674_RS09830	COG0753	catalase activity
EA674_RS09845	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EA674_RS09910	COG3433	isochorismatase activity
EA674_RS09910	COG1535	isochorismatase
EA674_RS09915	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS09920	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EA674_RS09925	COG4149	molybdate abc transporter
EA674_RS09930	COG0725	ABC transporter, periplasmic molybdate-binding protein
EA674_RS09940	COG4638	Rieske (2fe-2S)
EA674_RS09945	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA674_RS09950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA674_RS09950	COG0543	2 iron, 2 sulfur cluster binding
EA674_RS09975	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS09990	COG2207	Transcriptional regulator
EA674_RS10000	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS10005	COG2610	gluconate transmembrane transporter activity
EA674_RS10015	COG0583	DNA-binding transcription factor activity
EA674_RS10025	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA674_RS10030	COG2031	fatty acid transporter
EA674_RS10035	COG0183	Belongs to the thiolase family
EA674_RS10040	COG0583	DNA-binding transcription factor activity
EA674_RS10045	COG0583	DNA-binding transcription factor activity
EA674_RS10060	COG1027	Aspartate ammonia-lyase
EA674_RS10070	COG0477	Major facilitator Superfamily
EA674_RS10090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA674_RS10095	COG4521	taurine ABC transporter
EA674_RS10110	COG2188	Transcriptional regulator
EA674_RS10120	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EA674_RS10125	COG1733	regulation of RNA biosynthetic process
EA674_RS10130	COG2207	Transcriptional regulator
EA674_RS10130	COG3708	Transcriptional regulator
EA674_RS10145	COG0730	response to heat
EA674_RS10155	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA674_RS10155	COG3453	Protein conserved in bacteria
EA674_RS10165	COG3781	membrane
EA674_RS10170	COG1063	alcohol dehydrogenase
EA674_RS10180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA674_RS10185	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA674_RS10190	COG0022	dehydrogenase e1 component
EA674_RS10195	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EA674_RS10200	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA674_RS10215	COG3706	GGDEF domain
EA674_RS10230	COG0133	tryptophan synthase activity
EA674_RS10240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA674_RS10275	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EA674_RS10300	COG2226	methyltransferase
EA674_RS10355	COG0842	Transport permease protein
EA674_RS10360	COG0842	Transport permease protein
EA674_RS10365	COG1131	(ABC) transporter
EA674_RS10380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA674_RS10385	COG4773	Receptor
EA674_RS10405	COG0730	response to heat
EA674_RS10410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EA674_RS10430	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EA674_RS10490	COG4264	IucA IucC family
EA674_RS10495	COG4264	IucA IucC family
EA674_RS10515	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EA674_RS10530	COG1960	acyl-CoA dehydrogenase activity
EA674_RS10535	COG1960	acyl-CoA dehydrogenase activity
EA674_RS10540	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA674_RS10545	COG2207	Transcriptional regulator
EA674_RS10550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA674_RS10555	COG0776	regulation of translation
EA674_RS10580	COG0822	iron-sulfur transferase activity
EA674_RS10585	COG0316	Belongs to the HesB IscA family
EA674_RS10615	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EA674_RS10635	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA674_RS10640	COG0702	epimerase
EA674_RS10675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EA674_RS10685	COG0339	signal peptide processing
EA674_RS10735	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EA674_RS10740	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EA674_RS10770	COG0776	regulation of translation
EA674_RS10835	COG0084	hydrolase, TatD family'
EA674_RS10855	COG1663	tetraacyldisaccharide 4'-kinase activity
EA674_RS10860	COG1132	(ABC) transporter
EA674_RS10870	COG0811	peptide transport
EA674_RS10875	COG1475	DNA binding
EA674_RS10880	COG1192	Involved in chromosome partitioning
EA674_RS10890	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EA674_RS10905	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA674_RS10910	COG0191	fructose-bisphosphate aldolase activity
EA674_RS10930	COG0424	maF-like protein
EA674_RS10935	COG2850	peptidyl-arginine hydroxylation
EA674_RS10945	COG0640	Transcriptional regulator
EA674_RS10955	COG3619	membrane
EA674_RS10960	COG3122	Protein conserved in bacteria
EA674_RS10965	COG1132	(ABC) transporter
EA674_RS10985	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EA674_RS10990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA674_RS11000	COG0506	proline dehydrogenase activity
EA674_RS11000	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA674_RS11000	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA674_RS11005	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EA674_RS11020	COG3698	Phosphodiester glycosidase
EA674_RS11030	COG2353	YceI-like domain
EA674_RS11040	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EA674_RS11090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EA674_RS11090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EA674_RS11115	COG3539	Fimbrial protein
EA674_RS11120	COG3121	Chaperone
EA674_RS11150	COG0697	spore germination
EA674_RS11160	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA674_RS11170	COG0583	DNA-binding transcription factor activity
EA674_RS11190	COG1309	transcriptional regulator
EA674_RS11205	COG1522	sequence-specific DNA binding
EA674_RS11215	COG1126	abc transporter atp-binding protein
EA674_RS11220	COG0765	amino acid transport
EA674_RS11225	COG0765	amino acid transport
EA674_RS11255	COG1464	Belongs to the NlpA lipoprotein family
EA674_RS11265	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA674_RS11270	COG2011	ABC-type metal ion transport system permease component
EA674_RS11275	COG0012	GTP binding
EA674_RS11300	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA674_RS11340	COG0386	Belongs to the glutathione peroxidase family
EA674_RS11350	COG0436	Aminotransferase
EA674_RS11390	COG3634	alkyl hydroperoxide reductase activity
EA674_RS11405	COG0583	DNA-binding transcription factor activity
EA674_RS11410	COG0798	PFAM Bile acid sodium symporter
EA674_RS11415	COG0640	Transcriptional regulator
EA674_RS11430	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EA674_RS11440	COG0583	DNA-binding transcription factor activity
EA674_RS11450	COG1953	Uracil, thiamine, allantoin
EA674_RS11460	COG2175	clavaminate synthase activity
EA674_RS11465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA674_RS11470	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EA674_RS11475	COG4521	taurine ABC transporter
EA674_RS11485	COG0477	Major facilitator Superfamily
EA674_RS11510	COG1271	oxidase subunit
EA674_RS11515	COG1294	oxidase, subunit
EA674_RS11525	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA674_RS11545	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EA674_RS11565	COG3052	prosthetic group binding
EA674_RS11570	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EA674_RS11580	COG2814	Major facilitator Superfamily
EA674_RS11600	COG1346	cytolysis
EA674_RS11610	COG0583	DNA-binding transcription factor activity
EA674_RS11615	COG0625	glutathione transferase activity
EA674_RS11620	COG0625	glutathione transferase activity
EA674_RS11625	COG0583	DNA-binding transcription factor activity
EA674_RS11640	COG1045	serine acetyltransferase
EA674_RS11645	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA674_RS11650	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EA674_RS11660	COG1280	lysine exporter protein (LysE YggA)
EA674_RS11675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA674_RS11680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA674_RS11685	COG1126	abc transporter atp-binding protein
EA674_RS11690	COG0765	amino acid transport
EA674_RS11695	COG0765	amino acid transport
EA674_RS11715	COG0784	Response regulator, receiver
EA674_RS11715	COG2205	protein histidine kinase activity
EA674_RS11735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EA674_RS11755	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS11800	COG0583	DNA-binding transcription factor activity
EA674_RS11820	COG0318	PFAM AMP-dependent synthetase and ligase
EA674_RS11825	COG1309	transcriptional regulator
EA674_RS11830	COG1960	acyl-CoA dehydrogenase activity
EA674_RS11835	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA674_RS11840	COG1024	Enoyl-CoA hydratase
EA674_RS11845	COG4770	biotin carboxylase activity
EA674_RS11855	COG0583	DNA-binding transcription factor activity
EA674_RS11870	COG1960	acyl-CoA dehydrogenase activity
EA674_RS11880	COG2814	Major facilitator Superfamily
EA674_RS11890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA674_RS11895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA674_RS11900	COG2814	Major facilitator Superfamily
EA674_RS11905	COG1960	acyl-CoA dehydrogenase activity
EA674_RS11910	COG1024	Enoyl-CoA hydratase
EA674_RS11915	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS11920	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA674_RS11925	COG0183	Belongs to the thiolase family
EA674_RS11935	COG2814	Major facilitator Superfamily
EA674_RS11945	COG1024	Enoyl-CoA hydratase
EA674_RS11960	COG1960	acyl-CoA dehydrogenase activity
EA674_RS11965	COG2814	Major facilitator Superfamily
EA674_RS11970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EA674_RS11975	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EA674_RS11990	COG3842	ATPase activity
EA674_RS11995	COG1840	ABC-type Fe3 transport system, periplasmic component
EA674_RS12005	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA674_RS12010	COG1414	Transcriptional regulator
EA674_RS12020	COG0583	DNA-binding transcription factor activity
EA674_RS12025	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA674_RS12030	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS12040	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA674_RS12050	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS12055	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA674_RS12060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA674_RS12065	COG2267	carboxylic ester hydrolase activity
EA674_RS12085	COG3038	cytochrome b561
EA674_RS12090	COG0753	catalase activity
EA674_RS12130	COG2050	protein possibly involved in aromatic compounds catabolism
EA674_RS12140	COG3327	negative regulation of DNA-templated transcription, initiation
EA674_RS12145	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EA674_RS12150	COG0183	Belongs to the thiolase family
EA674_RS12155	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA674_RS12160	COG1024	Enoyl-CoA hydratase
EA674_RS12165	COG1024	Enoyl-CoA hydratase
EA674_RS12170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA674_RS12175	COG2151	metal-sulfur cluster biosynthetic enzyme
EA674_RS12180	COG3396	Phenylacetate-CoA oxygenase
EA674_RS12185	COG3460	Phenylacetate-CoA oxygenase
EA674_RS12190	COG3396	Phenylacetate-CoA oxygenase
EA674_RS12195	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS12195	COG2030	dehydratase
EA674_RS12200	COG1760	l-serine dehydratase
EA674_RS12205	COG0531	amino acid
EA674_RS12210	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS12225	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA674_RS12235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA674_RS12255	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA674_RS12270	COG0789	Transcriptional regulator
EA674_RS12285	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EA674_RS12300	COG2807	transmembrane transport
EA674_RS12305	COG0590	tRNA wobble adenosine to inosine editing
EA674_RS12425	COG1116	anion transmembrane transporter activity
EA674_RS12430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA674_RS12440	COG0864	Transcriptional regulator
EA674_RS12460	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA674_RS12465	COG0439	Biotin carboxylase
EA674_RS12480	COG1063	alcohol dehydrogenase
EA674_RS12490	COG1309	transcriptional regulator
EA674_RS12515	COG0038	chloride channel
EA674_RS12520	COG4770	biotin carboxylase activity
EA674_RS12540	COG1914	H( )-stimulated, divalent metal cation uptake system
EA674_RS12545	COG0583	DNA-binding transcription factor activity
EA674_RS12600	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA674_RS12620	COG2814	Major facilitator Superfamily
EA674_RS12635	COG1560	Kdo2-lipid A biosynthetic process
EA674_RS12645	COG5006	permease, DMT superfamily
EA674_RS12650	COG1522	sequence-specific DNA binding
EA674_RS12665	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EA674_RS12675	COG4122	O-methyltransferase activity
EA674_RS12705	COG1538	Outer membrane efflux protein
EA674_RS12710	COG1137	ATPase activity
EA674_RS12715	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EA674_RS12725	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EA674_RS12730	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EA674_RS12730	COG0517	IMP dehydrogenase activity
EA674_RS12770	COG2814	Major facilitator Superfamily
EA674_RS12810	COG1278	Cold shock
EA674_RS12815	COG1280	lysine exporter protein (LysE YggA)
EA674_RS12845	COG1570	exodeoxyribonuclease VII activity
EA674_RS12900	COG0583	DNA-binding transcription factor activity
EA674_RS12905	COG4638	Rieske (2fe-2S)
EA674_RS12910	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA674_RS12915	COG0633	Ferredoxin
EA674_RS12915	COG0543	2 iron, 2 sulfur cluster binding
EA674_RS12920	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS12925	COG3135	benzoate transporter
EA674_RS12930	COG2814	Major facilitator Superfamily
EA674_RS12945	COG1643	Atp-dependent helicase
EA674_RS12950	COG0450	alkyl hydroperoxide reductase
EA674_RS12960	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EA674_RS12970	COG3634	alkyl hydroperoxide reductase activity
EA674_RS12990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EA674_RS12995	COG0625	glutathione transferase activity
EA674_RS13005	COG2885	chlorophyll binding
EA674_RS13040	COG0542	response to heat
EA674_RS13055	COG1765	OsmC-like protein
EA674_RS13065	COG0667	Aldo Keto reductase
EA674_RS13080	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EA674_RS13090	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EA674_RS13100	COG0527	aspartate kinase activity
EA674_RS13110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EA674_RS13120	COG3038	cytochrome b561
EA674_RS13125	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EA674_RS13130	COG2252	PERMEase
EA674_RS13140	COG2072	flavoprotein involved in K transport
EA674_RS13165	COG1309	transcriptional regulator
EA674_RS13175	COG0300	oxidoreductase activity
EA674_RS13240	COG4269	membrane
EA674_RS13255	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA674_RS13255	COG1902	pentaerythritol trinitrate reductase activity
EA674_RS13265	COG5001	Diguanylate cyclase
EA674_RS13265	COG2203	Gaf domain
EA674_RS13265	COG3706	GGDEF domain
EA674_RS13265	COG4251	negative regulation of phosphorylation
EA674_RS13275	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA674_RS13295	COG4172	Belongs to the ABC transporter superfamily
EA674_RS13300	COG4239	(ABC) transporter, permease
EA674_RS13305	COG4174	ABC transporter (Permease)
EA674_RS13315	COG1388	LysM domain
EA674_RS13315	COG0741	lytic transglycosylase activity
EA674_RS13315	COG1388	LysM domain
EA674_RS13315	COG0741	lytic transglycosylase activity
EA674_RS13320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA674_RS13360	COG0583	DNA-binding transcription factor activity
EA674_RS13365	COG1279	arginine transmembrane transporter activity
EA674_RS13385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA674_RS13390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA674_RS13395	COG0006	proline dipeptidase activity
EA674_RS13430	COG2194	sulfuric ester hydrolase activity
EA674_RS13475	COG0739	heme binding
EA674_RS13800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EA674_RS13825	COG3384	dioxygenase
EA674_RS13835	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EA674_RS13840	COG2878	Part of a membrane complex involved in electron transport
EA674_RS13845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EA674_RS13870	COG0768	penicillin binding
EA674_RS13875	COG0742	ribosomal rna small subunit methyltransferase
EA674_RS13890	COG0830	nickel cation binding
EA674_RS13900	COG0804	urea catabolic process
EA674_RS13940	COG1253	flavin adenine dinucleotide binding
EA674_RS13950	COG2851	Citrate transporter
EA674_RS14000	COG1773	rubredoxin
EA674_RS14005	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA674_RS14015	COG0583	DNA-binding transcription factor activity
EA674_RS14040	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EA674_RS14045	COG4181	ATPase activity
EA674_RS14090	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EA674_RS14110	COG0306	phosphate transporter
EA674_RS14120	COG3958	Transketolase
EA674_RS14125	COG3959	Transketolase, thiamine diphosphate binding domain
EA674_RS14130	COG2271	Major facilitator Superfamily
EA674_RS14135	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS14140	COG0583	DNA-binding transcription factor activity
EA674_RS14160	COG2223	nitrite transmembrane transporter activity
EA674_RS14165	COG2207	Transcriptional regulator
EA674_RS14170	COG2066	Belongs to the glutaminase family
EA674_RS14175	COG0242	peptide deformylase activity
EA674_RS14180	COG0477	Major facilitator Superfamily
EA674_RS14190	COG0028	Belongs to the TPP enzyme family
EA674_RS14205	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS14210	COG2267	carboxylic ester hydrolase activity
EA674_RS14220	COG2271	Major facilitator Superfamily
EA674_RS14225	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA674_RS14235	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS14255	COG1414	Transcriptional regulator
EA674_RS14270	COG1024	Enoyl-CoA hydratase
EA674_RS14280	COG1215	transferase activity, transferring glycosyl groups
EA674_RS14285	COG1649	PFAM Uncharacterised BCR, COG1649
EA674_RS14285	COG0726	polysaccharide deacetylase
EA674_RS14295	COG4681	YaeQ
EA674_RS14305	COG0523	cobalamin synthesis protein
EA674_RS14315	COG1607	acyl-coa hydrolase
EA674_RS14325	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA674_RS14330	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA674_RS14335	COG1309	transcriptional regulator
EA674_RS14360	COG2040	homocysteine
EA674_RS14365	COG0531	amino acid
EA674_RS14420	COG1595	DNA-templated transcription, initiation
EA674_RS14430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA674_RS14435	COG0477	Major facilitator Superfamily
EA674_RS14560	COG0582	viral genome integration into host DNA
EA674_RS14570	COG0405	Gamma-glutamyltransferase
EA674_RS14575	COG2814	Major facilitator Superfamily
EA674_RS14585	COG2050	protein possibly involved in aromatic compounds catabolism
EA674_RS14600	COG1090	epimerase
EA674_RS14620	COG0420	3'-5' exonuclease activity
EA674_RS14645	COG0735	belongs to the Fur family
EA674_RS14650	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EA674_RS14675	COG0121	glutamine amidotransferase
EA674_RS14690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA674_RS14700	COG0210	DNA helicase
EA674_RS14705	COG2885	chlorophyll binding
EA674_RS14710	COG0204	Acyl-transferase
EA674_RS14725	COG2894	cell division
EA674_RS14745	COG1280	lysine exporter protein (LysE YggA)
EA674_RS14750	COG1674	ftsk spoiiie
EA674_RS14750	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EA674_RS14755	COG0492	ferredoxin-NADP+ reductase activity
EA674_RS14760	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EA674_RS14770	COG0456	acetyltransferase
EA674_RS14815	COG1981	membrane
EA674_RS14830	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA674_RS14830	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EA674_RS14850	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS14860	COG0657	acetylesterase activity
EA674_RS14870	COG0473	3-isopropylmalate dehydrogenase activity
EA674_RS14875	COG0583	DNA-binding transcription factor activity
EA674_RS14895	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA674_RS14920	COG0564	pseudouridine synthase activity
EA674_RS14930	COG0358	DNA primase activity
EA674_RS14945	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EA674_RS14975	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA674_RS15005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EA674_RS15015	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA674_RS15015	COG0352	thiamine-phosphate diphosphorylase activity
EA674_RS15015	COG0351	phosphomethylpyrimidine kinase
EA674_RS15020	COG1652	LysM domain
EA674_RS15045	COG1399	metal-binding, possibly nucleic acid-binding protein
EA674_RS15050	COG3101	peptidyl-lysine hydroxylation
EA674_RS15055	COG0009	L-threonylcarbamoyladenylate synthase
EA674_RS15060	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EA674_RS15065	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EA674_RS15080	COG4106	trans-aconitate 2-methyltransferase activity
EA674_RS15095	COG2226	methyltransferase
EA674_RS15095	COG0596	Alpha beta hydrolase
EA674_RS15095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA674_RS15100	COG1877	trehalose-phosphatase activity
EA674_RS15105	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EA674_RS15110	COG2223	nitrite transmembrane transporter activity
EA674_RS15130	COG1196	nuclear chromosome segregation
EA674_RS15140	COG0730	response to heat
EA674_RS15155	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EA674_RS15165	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA674_RS15225	COG0489	protein tyrosine kinase activity
EA674_RS15235	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA674_RS15235	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA674_RS15265	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EA674_RS15270	COG2081	HI0933 family
EA674_RS15280	COG0668	transmembrane transport
EA674_RS15300	COG0583	DNA-binding transcription factor activity
EA674_RS15320	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EA674_RS15325	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA674_RS15355	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EA674_RS15395	COG0745	RESPONSE REGULATOR receiver
EA674_RS15415	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EA674_RS15425	COG2205	protein histidine kinase activity
EA674_RS15495	COG4993	Dehydrogenase
EA674_RS15515	COG0384	phenazine biosynthesis protein PhzF
EA674_RS15545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA674_RS15560	COG0583	DNA-binding transcription factor activity
EA674_RS15590	COG0583	DNA-binding transcription factor activity
EA674_RS15610	COG0583	DNA-binding transcription factor activity
EA674_RS15615	COG1053	succinate dehydrogenase
EA674_RS15625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EA674_RS15630	COG2814	Major facilitator Superfamily
EA674_RS15635	COG1960	acyl-CoA dehydrogenase activity
EA674_RS15640	COG0583	DNA-binding transcription factor activity
EA674_RS15645	COG1063	alcohol dehydrogenase
EA674_RS15675	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EA674_RS15680	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EA674_RS15685	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA674_RS15700	COG3667	copper resistance
EA674_RS15705	COG2132	Multicopper oxidase
EA674_RS15715	COG0561	phosphatase activity
EA674_RS15720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EA674_RS15745	COG1214	PFAM Peptidase M22, glycoprotease
EA674_RS15795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EA674_RS15805	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EA674_RS15810	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EA674_RS15815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EA674_RS15875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA674_RS15885	COG1846	Transcriptional regulator
EA674_RS15890	COG1764	response to oxidative stress
EA674_RS15930	COG0037	tRNA processing
EA674_RS15940	COG0248	Ppx GppA phosphatase
EA674_RS15970	COG0072	phenylalanine-tRNA ligase activity
EA674_RS16010	COG1238	metal cluster binding
EA674_RS16015	COG0625	glutathione transferase activity
EA674_RS16035	COG0318	PFAM AMP-dependent synthetase and ligase
EA674_RS16040	COG3028	Belongs to the UPF0307 family
EA674_RS16045	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA674_RS16065	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EA674_RS16070	COG0617	tRNA 3'-terminal CCA addition
EA674_RS16075	COG1555	photosystem II stabilization
EA674_RS16080	COG3956	TIGRFAM MazG family protein
EA674_RS16090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA674_RS16110	COG5002	protein histidine kinase activity
EA674_RS16110	COG2205	protein histidine kinase activity
EA674_RS16110	COG0784	Response regulator, receiver
EA674_RS16115	COG1024	Enoyl-CoA hydratase
EA674_RS16120	COG2084	Dehydrogenase
EA674_RS16125	COG3622	Belongs to the hyi family
EA674_RS16155	COG0697	spore germination
EA674_RS16165	COG2814	Major facilitator Superfamily
EA674_RS16170	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA674_RS16180	COG0583	DNA-binding transcription factor activity
EA674_RS16190	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EA674_RS16205	COG0084	hydrolase, TatD family'
EA674_RS16220	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EA674_RS16255	COG0440	acetolactate synthase activity
EA674_RS16260	COG0028	Belongs to the TPP enzyme family
EA674_RS16285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA674_RS16290	COG1136	(ABC) transporter
EA674_RS16290	COG0577	efflux transmembrane transporter activity
EA674_RS16295	COG1538	Outer membrane efflux protein
EA674_RS16310	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EA674_RS16315	COG1162	GTPase activity
EA674_RS16325	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EA674_RS16345	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EA674_RS16350	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS16390	COG2986	histidine ammonia-lyase
EA674_RS16405	COG0318	PFAM AMP-dependent synthetase and ligase
EA674_RS16415	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA674_RS16460	COG1426	Protein conserved in bacteria
EA674_RS16495	COG0793	Belongs to the peptidase S41A family
EA674_RS16510	COG2267	carboxylic ester hydrolase activity
EA674_RS16520	COG1012	belongs to the aldehyde dehydrogenase family
EA674_RS16525	COG3265	gluconokinase activity
EA674_RS16535	COG0800	Aldolase
EA674_RS16545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EA674_RS16550	COG0857	belongs to the CobB CobQ family
EA674_RS16550	COG0280	phosphate acetyltransferase
EA674_RS16555	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EA674_RS16555	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EA674_RS16575	COG0740	serine-type endopeptidase activity
EA674_RS16585	COG4774	siderophore transport
EA674_RS16595	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EA674_RS16605	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA674_RS16605	COG2813	Specifically methylates the guanine in position
EA674_RS16705	COG0788	formyltetrahydrofolate deformylase activity
EA674_RS16730	COG4651	solute:proton antiporter activity
EA674_RS16730	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA674_RS16750	COG0724	RNA recognition motif
EA674_RS16755	COG0210	DNA helicase
EA674_RS16780	COG1733	regulation of RNA biosynthetic process
EA674_RS16790	COG2900	Belongs to the SlyX family
EA674_RS16795	COG0488	(ABC) transporter
EA674_RS16800	COG1280	lysine exporter protein (LysE YggA)
EA674_RS16805	COG1560	Kdo2-lipid A biosynthetic process
EA674_RS16815	COG1301	dicarboxylic acid transport
EA674_RS16870	COG0473	3-isopropylmalate dehydrogenase activity
EA674_RS16935	COG0583	DNA-binding transcription factor activity
EA674_RS16945	COG0625	glutathione transferase activity
EA674_RS16950	COG2378	regulation of single-species biofilm formation
EA674_RS16955	COG0546	phosphoglycolate phosphatase activity
EA674_RS16970	COG1530	ribonuclease E activity
EA674_RS16975	COG0318	PFAM AMP-dependent synthetase and ligase
EA674_RS16990	COG0583	DNA-binding transcription factor activity
EA674_RS16995	COG4221	oxidoreductase activity
EA674_RS17000	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EA674_RS17010	COG0534	Mate efflux family protein
EA674_RS17025	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EA674_RS17065	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EA674_RS17070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA674_RS17085	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA674_RS17095	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EA674_RS17095	COG0644	oxidoreductase
EA674_RS17100	COG0425	Belongs to the sulfur carrier protein TusA family
EA674_RS17105	COG4535	Mg2 and Co2 transporter CorC
EA674_RS17115	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA674_RS17135	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EA674_RS17140	COG0475	glutathione-regulated potassium exporter activity
EA674_RS17140	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA674_RS17145	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EA674_RS17155	COG0484	heat shock protein binding
EA674_RS17160	COG0789	Transcriptional regulator
EA674_RS17165	COG0598	Magnesium transport protein CorA
EA674_RS17180	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EA674_RS17185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA674_RS17190	COG1074	ATP-dependent DNA helicase activity
EA674_RS17195	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EA674_RS17215	COG2226	methyltransferase
EA674_RS17230	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA674_RS17235	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EA674_RS17250	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA674_RS17250	COG2111	Na H antiporter
EA674_RS17255	COG1006	Multisubunit Na H antiporter MnhC subunit
EA674_RS17260	COG0651	ATP synthesis coupled electron transport
EA674_RS17265	COG1863	multisubunit Na H antiporter MnhE subunit
EA674_RS17270	COG2212	antiporter activity
EA674_RS17275	COG1320	monovalent cation:proton antiporter activity
EA674_RS17290	COG0195	Participates in both transcription termination and antitermination
EA674_RS17340	COG0237	dephospho-CoA kinase activity
EA674_RS17350	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA674_RS17365	COG0497	DNA recombination
EA674_RS17375	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EA674_RS17405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA674_RS17405	COG2169	Transcriptional regulator
EA674_RS17410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EA674_RS17480	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EA674_RS17495	COG0326	Molecular chaperone. Has ATPase activity
EA674_RS17510	COG2056	Na+-H+ antiporter family
EA674_RS17515	COG0596	Alpha beta hydrolase
EA674_RS17610	COG0546	phosphoglycolate phosphatase activity
EA674_RS17615	COG1716	ATPase activity
EA674_RS17660	COG0181	hydroxymethylbilane synthase activity
EA674_RS17670	COG3275	phosphorelay sensor kinase activity
EA674_RS17690	COG1538	Outer membrane efflux protein
EA674_RS17695	COG0697	spore germination
EA674_RS17720	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA674_RS17725	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EA674_RS17730	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA674_RS17735	COG0772	Belongs to the SEDS family
EA674_RS17760	COG4974	Belongs to the 'phage' integrase family
EA674_RS17765	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA674_RS17775	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EA674_RS17785	COG2197	response regulator
EA674_RS17800	COG0793	Belongs to the peptidase S41A family
EA674_RS17805	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EA674_RS17810	COG0795	lipopolysaccharide-transporting ATPase activity
EA674_RS17850	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA674_RS17850	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA674_RS17860	COG0004	ammonium transporteR
EA674_RS17865	COG0347	Belongs to the P(II) protein family
EA674_RS17875	COG0606	chelatase, subunit chli
EA674_RS17930	COG0659	secondary active sulfate transmembrane transporter activity
EA674_RS17935	COG0589	response to stress
EA674_RS17985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA674_RS18035	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EA674_RS18065	COG0659	secondary active sulfate transmembrane transporter activity
EA674_RS18070	COG0589	response to stress
EA674_RS18100	COG0606	chelatase, subunit chli
EA674_RS18105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA674_RS18115	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA674_RS18130	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EA674_RS18145	COG0318	PFAM AMP-dependent synthetase and ligase
EA674_RS18155	COG0477	Major facilitator Superfamily
EA674_RS18160	COG2860	membrane
EA674_RS18170	COG1253	flavin adenine dinucleotide binding
EA674_RS18190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EA674_RS18225	COG0655	NAD(P)H dehydrogenase (quinone) activity
EA674_RS18235	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EA674_RS18270	COG1309	transcriptional regulator
EA674_RS18305	COG0758	DNA mediated transformation
EA674_RS18315	COG0697	spore germination
EA674_RS18320	COG1309	transcriptional regulator
EA674_RS18335	COG0386	Belongs to the glutathione peroxidase family
EA674_RS18400	COG1121	(ABC) transporter
EA674_RS18405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EA674_RS18410	COG1280	lysine exporter protein (LysE YggA)
EA674_RS18415	COG2837	iron assimilation
EA674_RS18425	COG0281	malic enzyme
EA674_RS18470	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA674_RS18470	COG0519	Catalyzes the synthesis of GMP from XMP
EA674_RS18475	COG4399	Belongs to the UPF0754 family
EA674_RS18480	COG2259	Doxx family
EA674_RS18485	COG0586	Pfam SNARE associated Golgi protein
EA674_RS18500	COG1192	Involved in chromosome partitioning
EA674_RS18510	COG0271	Belongs to the BolA IbaG family
EA674_RS18530	COG2267	carboxylic ester hydrolase activity
EA674_RS18550	COG0318	PFAM AMP-dependent synthetase and ligase
EA674_RS18550	COG0300	oxidoreductase activity
EA674_RS18550	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA674_RS18550	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS18550	COG3321	synthase
EA674_RS18555	COG1960	acyl-CoA dehydrogenase activity
EA674_RS18565	COG2197	response regulator
EA674_RS18575	COG3916	Acyl-homoserine-lactone synthase
EA674_RS18580	COG0477	Major facilitator Superfamily
EA674_RS18585	COG1024	Enoyl-CoA hydratase
EA674_RS18590	COG1024	Enoyl-CoA hydratase
EA674_RS18595	COG1960	acyl-CoA dehydrogenase activity
EA674_RS18600	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA674_RS18620	COG1113	amino acid transport
EA674_RS18625	COG1113	amino acid transport
EA674_RS18630	COG0251	oxidation-reduction process
EA674_RS18670	COG0564	pseudouridine synthase activity
EA674_RS18735	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EA674_RS18750	COG1802	Transcriptional regulator
EA674_RS18760	COG1448	Aminotransferase
EA674_RS18765	COG0277	FAD linked oxidase domain protein
EA674_RS18775	COG2186	Transcriptional regulator
EA674_RS18785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA674_RS18790	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA674_RS18805	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EA674_RS18815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EA674_RS18825	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EA674_RS18830	COG0438	transferase activity, transferring glycosyl groups
EA674_RS18850	COG1216	Glycosyl transferase, family 2
EA674_RS18855	COG5039	Polysaccharide pyruvyl transferase
EA674_RS18865	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EA674_RS18870	COG1596	polysaccharide export
EA674_RS18895	COG0728	peptidoglycan biosynthetic process
EA674_RS18900	COG3023	N-Acetylmuramoyl-L-alanine amidase
EA674_RS18955	COG0546	phosphoglycolate phosphatase activity
EA674_RS18960	COG1028	Short-chain dehydrogenase reductase Sdr
EA674_RS18980	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA674_RS18985	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA674_RS18990	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA674_RS18995	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA674_RS19000	COG1116	anion transmembrane transporter activity
EA674_RS19005	COG1309	transcriptional regulator
EA674_RS19010	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EA674_RS19020	COG0196	riboflavin kinase activity
EA674_RS19025	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EA674_RS19035	COG1047	Peptidyl-prolyl cis-trans
EA674_RS19075	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EA674_RS19080	COG0657	acetylesterase activity
EA674_RS19130	COG2951	lytic endotransglycosylase activity
EA674_RS19135	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EA674_RS19155	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EA674_RS19165	COG0671	phosphoesterase, PA-phosphatase related
EA674_RS19170	COG0861	Integral membrane protein TerC family
EA674_RS19180	COG0754	glutathionylspermidine amidase activity
EA674_RS19190	COG0402	S-adenosylhomocysteine deaminase activity
EA674_RS19205	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA674_RS19210	COG1230	cation diffusion facilitator family transporter
EA674_RS19225	COG0706	membrane insertase activity
EA674_RS19295	COG1525	nuclease
EA674_RS19360	COG1475	DNA binding
EA674_RS19380	COG3853	Toxic anion resistance protein (TelA)
EA674_RS19570	COG0741	lytic transglycosylase activity
EA674_RS19605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process