locus-tag	class	description
EA714_RS00010	COG0592	DNA-directed DNA polymerase activity
EA714_RS00020	COG0187	DNA topoisomerase II activity
EA714_RS00030	COG0586	Pfam SNARE associated Golgi protein
EA714_RS00035	COG0488	(ABC) transporter
EA714_RS00060	COG0596	Alpha beta hydrolase
EA714_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
EA714_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
EA714_RS00115	COG0733	neurotransmitter:sodium symporter activity
EA714_RS00155	COG2233	PERMEase
EA714_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_RS00205	COG2814	Major facilitator Superfamily
EA714_RS00210	COG0656	L-ascorbic acid biosynthetic process
EA714_RS00215	COG0583	DNA-binding transcription factor activity
EA714_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_RS00235	COG1064	alcohol dehydrogenase
EA714_RS00240	COG2818	Glycosylase
EA714_RS00255	COG1194	a g-specific adenine glycosylase
EA714_RS00275	COG2983	Belongs to the UPF0260 family
EA714_RS00280	COG2133	pyrroloquinoline quinone binding
EA714_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
EA714_RS00290	COG2116	formate transmembrane transporter activity
EA714_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA714_RS00315	COG1335	isochorismatase
EA714_RS00320	COG0385	Bile acid
EA714_RS00325	COG0534	Mate efflux family protein
EA714_RS00330	COG1683	Conserved Protein
EA714_RS00350	COG0625	glutathione transferase activity
EA714_RS00360	COG1113	amino acid transport
EA714_RS00370	COG0523	cobalamin synthesis protein
EA714_RS00380	COG2188	Transcriptional regulator
EA714_RS00410	COG0010	Belongs to the arginase family
EA714_RS00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA714_RS00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
EA714_RS00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
EA714_RS00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
EA714_RS00555	COG0534	Mate efflux family protein
EA714_RS00560	COG0436	Aminotransferase
EA714_RS00565	COG2733	membrane
EA714_RS00580	COG2918	glutathione biosynthetic process
EA714_RS00595	COG1388	LysM domain
EA714_RS00595	COG0791	NLP P60 protein
EA714_RS00615	COG3150	esterase
EA714_RS00625	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
EA714_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_RS00650	COG2233	PERMEase
EA714_RS00655	COG2351	hydroxyisourate hydrolase activity
EA714_RS00690	COG3706	GGDEF domain
EA714_RS00705	COG1393	Belongs to the ArsC family
EA714_RS00710	COG0708	Exodeoxyribonuclease III
EA714_RS00730	COG0189	ligase activity
EA714_RS00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
EA714_RS00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
EA714_RS00775	COG4942	peptidase
EA714_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA714_RS00795	COG2119	membrane
EA714_RS00800	COG4774	siderophore transport
EA714_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_RS00805	COG0426	domain, Protein
EA714_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
EA714_RS00850	COG1902	pentaerythritol trinitrate reductase activity
EA714_RS00855	COG1519	Transferase
EA714_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA714_RS00865	COG0668	transmembrane transport
EA714_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA714_RS00880	COG1335	isochorismatase
EA714_RS00885	COG1522	sequence-specific DNA binding
EA714_RS00890	COG3328	transposase activity
EA714_RS00915	COG0784	Response regulator, receiver
EA714_RS00915	COG2205	protein histidine kinase activity
EA714_RS00915	COG2198	Histidine kinase
EA714_RS00920	COG3162	membrane
EA714_RS00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA714_RS00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_RS00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
EA714_RS00960	COG1309	transcriptional regulator
EA714_RS00980	COG0351	phosphomethylpyrimidine kinase
EA714_RS00980	COG0352	thiamine-phosphate diphosphorylase activity
EA714_RS00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA714_RS00990	COG2814	Major facilitator Superfamily
EA714_RS01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA714_RS01015	COG1113	amino acid transport
EA714_RS01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA714_RS01030	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS01040	COG1335	isochorismatase
EA714_RS01070	COG2814	Major facilitator Superfamily
EA714_RS01075	COG0583	DNA-binding transcription factor activity
EA714_RS01095	COG0667	Aldo Keto reductase
EA714_RS01130	COG1733	regulation of RNA biosynthetic process
EA714_RS01140	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA714_RS01205	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
EA714_RS01220	COG2329	Antibiotic biosynthesis monooxygenase
EA714_RS01250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
EA714_RS01280	COG0427	acetyl-CoA hydrolase
EA714_RS01305	COG0659	secondary active sulfate transmembrane transporter activity
EA714_RS01310	COG4221	oxidoreductase activity
EA714_RS01315	COG2873	o-acetylhomoserine
EA714_RS01320	COG0488	(ABC) transporter
EA714_RS01405	COG0833	amino acid
EA714_RS01450	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
EA714_RS01455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
EA714_RS01470	COG2226	methyltransferase
EA714_RS01520	COG0069	glutamate synthase activity
EA714_RS01520	COG0070	glutamate synthase
EA714_RS01520	COG0067	glutamate synthase
EA714_RS01525	COG0493	'glutamate synthase
EA714_RS01535	COG1704	LemA family
EA714_RS01540	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
EA714_RS01550	COG4969	Belongs to the N-Me-Phe pilin family
EA714_RS01555	COG3307	-O-antigen
EA714_RS01575	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA714_RS01590	COG0194	GDP metabolic process
EA714_RS01640	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
EA714_RS01660	COG5380	lipid catabolic process
EA714_RS01665	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
EA714_RS01690	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
EA714_RS01695	COG0277	FAD linked oxidase domain protein
EA714_RS01705	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
EA714_RS01710	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA714_RS01725	COG1289	transmembrane transporter activity
EA714_RS01735	COG0628	permease
EA714_RS01740	COG1192	Involved in chromosome partitioning
EA714_RS01770	COG0833	amino acid
EA714_RS01775	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EA714_RS01780	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA714_RS01790	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS01830	COG0583	DNA-binding transcription factor activity
EA714_RS01875	COG0517	IMP dehydrogenase activity
EA714_RS01880	COG1983	PspC domain protein
EA714_RS01890	COG1960	acyl-CoA dehydrogenase activity
EA714_RS01905	COG0408	coproporphyrinogen oxidase activity
EA714_RS01925	COG0513	Belongs to the DEAD box helicase family
EA714_RS01935	COG1127	ABC transporter
EA714_RS01940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
EA714_RS01950	COG2854	intermembrane phospholipid transfer
EA714_RS01960	COG0598	Magnesium transport protein CorA
EA714_RS01970	COG0494	nUDIX hydrolase
EA714_RS01975	COG1040	competence protein
EA714_RS01980	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
EA714_RS02000	COG1946	Acyl-CoA thioesterase
EA714_RS02005	COG1301	dicarboxylic acid transport
EA714_RS02020	COG1959	2 iron, 2 sulfur cluster binding
EA714_RS02025	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA714_RS02025	COG1017	nitric oxide dioxygenase activity
EA714_RS02030	COG0433	COG0433 Predicted ATPase
EA714_RS02035	COG0626	cystathionine gamma-synthase activity
EA714_RS02190	COG1960	acyl-CoA dehydrogenase activity
EA714_RS02195	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
EA714_RS02225	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
EA714_RS02230	COG0339	signal peptide processing
EA714_RS02235	COG0557	exoribonuclease II activity
EA714_RS02280	COG0179	Fumarylacetoacetate (FAA) hydrolase
EA714_RS02285	COG2169	Transcriptional regulator
EA714_RS02290	COG0697	spore germination
EA714_RS02295	COG1295	ribonuclease BN
EA714_RS02330	COG1702	phosphate starvation-inducible protein PhoH
EA714_RS02340	COG1196	nuclear chromosome segregation
EA714_RS02340	COG0739	heme binding
EA714_RS02340	COG0741	lytic transglycosylase activity
EA714_RS02370	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
EA714_RS02375	COG1183	phosphatidylcholine synthase activity
EA714_RS02420	COG1960	acyl-CoA dehydrogenase activity
EA714_RS02425	COG1309	transcriptional regulator
EA714_RS02440	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA714_RS02445	COG1960	acyl-CoA dehydrogenase activity
EA714_RS02465	COG2969	positive regulation of protein catabolic process
EA714_RS02475	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
EA714_RS02490	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
EA714_RS02495	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
EA714_RS02515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
EA714_RS02525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EA714_RS02530	COG1408	metallophosphoesterase
EA714_RS02540	COG2199	diguanylate cyclase activity
EA714_RS02600	COG1607	acyl-coa hydrolase
EA714_RS02630	COG2350	Protein conserved in bacteria
EA714_RS02640	COG0613	PHP domain protein
EA714_RS02645	COG3781	membrane
EA714_RS02655	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
EA714_RS02660	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
EA714_RS02670	COG1862	Preprotein translocase
EA714_RS02720	COG2205	protein histidine kinase activity
EA714_RS02725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
EA714_RS02745	COG0726	polysaccharide deacetylase
EA714_RS02750	COG0463	Glycosyl transferase, family 2
EA714_RS02755	COG0438	transferase activity, transferring glycosyl groups
EA714_RS02820	COG0625	glutathione transferase activity
EA714_RS02825	COG0583	DNA-binding transcription factor activity
EA714_RS02830	COG1960	acyl-CoA dehydrogenase activity
EA714_RS02835	COG1960	acyl-CoA dehydrogenase activity
EA714_RS02845	COG2205	protein histidine kinase activity
EA714_RS02850	COG0745	RESPONSE REGULATOR receiver
EA714_RS02855	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
EA714_RS02875	COG2096	Adenosyltransferase
EA714_RS02925	COG0285	dihydrofolate synthase activity
EA714_RS02945	COG0450	alkyl hydroperoxide reductase
EA714_RS02960	COG0477	Major facilitator Superfamily
EA714_RS02965	COG1272	protein, Hemolysin III
EA714_RS02995	COG0183	Belongs to the thiolase family
EA714_RS03000	COG2207	Transcriptional regulator
EA714_RS03020	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_RS03040	COG0183	Belongs to the thiolase family
EA714_RS03050	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
EA714_RS03050	COG2885	chlorophyll binding
EA714_RS03060	COG1690	Belongs to the RtcB family
EA714_RS03065	COG0833	amino acid
EA714_RS03075	COG2233	PERMEase
EA714_RS03080	COG1217	gtp-binding protein TYPA
EA714_RS03105	COG2094	Belongs to the DNA glycosylase MPG family
EA714_RS03110	COG4772	TonB-dependent receptor
EA714_RS03115	COG1902	pentaerythritol trinitrate reductase activity
EA714_RS03120	COG0679	Auxin Efflux Carrier
EA714_RS03130	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA714_RS03135	COG0354	folic acid binding
EA714_RS03145	COG3189	MarR family transcriptional regulator
EA714_RS03150	COG2824	Alkylphosphonate utilization operon protein PhnA
EA714_RS03155	COG3422	double-strand break repair
EA714_RS03195	COG0840	transmembrane signaling receptor activity
EA714_RS03215	COG5510	response to toxic substance
EA714_RS03225	COG2832	Protein of unknown function (DUF454)
EA714_RS03230	COG1376	ErfK ybiS ycfS ynhG family protein
EA714_RS03270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
EA714_RS03280	COG1289	transmembrane transporter activity
EA714_RS03285	COG2814	Major facilitator Superfamily
EA714_RS03305	COG1115	amino acid carrier protein
EA714_RS03310	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA714_RS03315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA714_RS03320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
EA714_RS03350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA714_RS03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
EA714_RS03365	COG1077	Cell shape determining protein MreB Mrl
EA714_RS03370	COG1792	Involved in formation and maintenance of cell shape
EA714_RS03375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
EA714_RS03380	COG0424	maF-like protein
EA714_RS03385	COG1530	ribonuclease E activity
EA714_RS03395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA714_RS03405	COG0560	Phosphoserine phosphatase
EA714_RS03415	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA714_RS03440	COG2207	Transcriptional regulator
EA714_RS03460	COG1113	amino acid transport
EA714_RS03465	COG2828	Protein conserved in bacteria
EA714_RS03470	COG0142	geranyltranstransferase activity
EA714_RS03475	COG2315	Protein conserved in bacteria
EA714_RS03490	COG1752	Esterase of the alpha-beta hydrolase superfamily
EA714_RS03515	COG2194	sulfuric ester hydrolase activity
EA714_RS03520	COG0745	RESPONSE REGULATOR receiver
EA714_RS03525	COG0642	Histidine kinase
EA714_RS03535	COG0004	ammonium transporteR
EA714_RS03545	COG0583	DNA-binding transcription factor activity
EA714_RS03565	COG0525	valine-tRNA ligase activity
EA714_RS03575	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS03585	COG0393	Putative heavy-metal-binding
EA714_RS03590	COG0393	Putative heavy-metal-binding
EA714_RS03595	COG1538	Outer membrane efflux protein
EA714_RS03605	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_RS03610	COG0671	phosphoesterase, PA-phosphatase related
EA714_RS03640	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
EA714_RS03655	COG1648	precorrin-2 dehydrogenase activity
EA714_RS03655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
EA714_RS03660	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
EA714_RS03665	COG1733	regulation of RNA biosynthetic process
EA714_RS03675	COG0531	amino acid
EA714_RS03690	COG0321	lipoyl(octanoyl) transferase activity
EA714_RS03695	COG2921	Belongs to the UPF0250 family
EA714_RS03735	COG2009	succinate dehydrogenase
EA714_RS03740	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
EA714_RS03745	COG1053	succinate dehydrogenase
EA714_RS03750	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
EA714_RS03775	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA714_RS03795	COG2354	Protein conserved in bacteria
EA714_RS03800	COG2321	neutral zinc metallopeptidase
EA714_RS03840	COG2843	Capsule synthesis protein
EA714_RS03855	COG0589	response to stress
EA714_RS03875	COG0505	Belongs to the CarA family
EA714_RS03900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA714_RS03905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
EA714_RS03955	COG0477	Major facilitator Superfamily
EA714_RS03960	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
EA714_RS03975	COG1597	lipid kinase activity
EA714_RS03980	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA714_RS04005	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA714_RS04010	COG0584	glycerophosphoryl diester phosphodiesterase
EA714_RS04030	COG0741	lytic transglycosylase activity
EA714_RS04055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
EA714_RS04070	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA714_RS04100	COG0778	Nitroreductase
EA714_RS04115	COG1929	Belongs to the glycerate kinase type-1 family
EA714_RS04120	COG0243	molybdopterin cofactor binding
EA714_RS04125	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
EA714_RS04130	COG3339	Conserved Protein
EA714_RS04140	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
EA714_RS04155	COG1113	amino acid transport
EA714_RS04165	COG0019	diaminopimelate decarboxylase activity
EA714_RS04175	COG1280	lysine exporter protein (LysE YggA)
EA714_RS04180	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EA714_RS04210	COG0463	Glycosyl transferase, family 2
EA714_RS04230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_RS04260	COG4591	ABC-type transport system involved in lipoprotein release permease component
EA714_RS04265	COG1136	(ABC) transporter
EA714_RS04270	COG0658	competence protein
EA714_RS04270	COG2333	competence protein COMEC
EA714_RS04280	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
EA714_RS04280	COG0616	signal peptide processing
EA714_RS04285	COG0596	Alpha beta hydrolase
EA714_RS04290	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
EA714_RS04300	COG0628	permease
EA714_RS04335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA714_RS04355	COG0823	Involved in the tonB-independent uptake of proteins
EA714_RS04375	COG0824	Thioesterase
EA714_RS04380	COG1473	amidohydrolase
EA714_RS04400	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
EA714_RS04400	COG0047	phosphoribosylformylglycinamidine synthase activity
EA714_RS04405	COG2814	Major facilitator Superfamily
EA714_RS04415	COG1024	Enoyl-CoA hydratase
EA714_RS04420	COG1056	cytidyltransferase-related domain
EA714_RS04420	COG1051	belongs to the nudix hydrolase family
EA714_RS04430	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
EA714_RS04445	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
EA714_RS04475	COG0583	DNA-binding transcription factor activity
EA714_RS04480	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
EA714_RS04485	COG4208	sulfate ABC transporter
EA714_RS04490	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
EA714_RS04500	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
EA714_RS04505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
EA714_RS04510	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
EA714_RS04530	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA714_RS04545	COG0681	Belongs to the peptidase S26 family
EA714_RS04560	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
EA714_RS04570	COG1381	Involved in DNA repair and RecF pathway recombination
EA714_RS04575	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
EA714_RS04585	COG4221	oxidoreductase activity
EA714_RS04615	COG0436	Aminotransferase
EA714_RS04635	COG0556	nucleotide-excision repair
EA714_RS04830	COG5410	chromosome segregation
EA714_RS05020	COG2070	2-Nitropropane dioxygenase
EA714_RS05050	COG1215	transferase activity, transferring glycosyl groups
EA714_RS05065	COG0415	Belongs to the DNA photolyase family
EA714_RS05075	COG1252	NADH dehydrogenase
EA714_RS05095	COG1187	pseudouridine synthase activity
EA714_RS05120	COG0477	Major facilitator Superfamily
EA714_RS05125	COG0583	DNA-binding transcription factor activity
EA714_RS05130	COG1823	symporter activity
EA714_RS05140	COG0612	Peptidase, M16
EA714_RS05165	COG0352	thiamine-phosphate diphosphorylase activity
EA714_RS05200	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA714_RS05215	COG1309	transcriptional regulator
EA714_RS05225	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
EA714_RS05230	COG0076	glutamate decarboxylase activity
EA714_RS05240	COG1522	sequence-specific DNA binding
EA714_RS05245	COG3961	Belongs to the TPP enzyme family
EA714_RS05250	COG1113	amino acid transport
EA714_RS05255	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
EA714_RS05260	COG0573	inorganic phosphate transmembrane transporter activity
EA714_RS05270	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
EA714_RS05275	COG0616	signal peptide processing
EA714_RS05310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
EA714_RS05315	COG1686	Belongs to the peptidase S11 family
EA714_RS05340	COG0583	DNA-binding transcription factor activity
EA714_RS05345	COG1067	ATP-dependent peptidase activity
EA714_RS05390	COG1966	Carbon starvation protein
EA714_RS05395	COG2879	small protein
EA714_RS05430	COG2508	Transcriptional regulator
EA714_RS05430	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
EA714_RS05450	COG1113	amino acid transport
EA714_RS05455	COG0583	DNA-binding transcription factor activity
EA714_RS05460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_RS05465	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_RS05475	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS05480	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_RS05485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA714_RS05485	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
EA714_RS05520	COG2814	Major facilitator Superfamily
EA714_RS05525	COG4948	Mandelate Racemase Muconate Lactonizing
EA714_RS05535	COG1309	transcriptional regulator
EA714_RS05555	COG1741	Belongs to the pirin family
EA714_RS05565	COG2964	Protein conserved in bacteria
EA714_RS05580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA714_RS05585	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EA714_RS05590	COG4605	iron ion homeostasis
EA714_RS05595	COG4604	ABC transporter, ATP-binding protein
EA714_RS05600	COG4607	ABC-type enterochelin transport system periplasmic component
EA714_RS05605	COG4774	siderophore transport
EA714_RS05615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
EA714_RS05620	COG1021	2,3-dihydroxybenzoate-AMP ligase
EA714_RS05625	COG3433	isochorismatase activity
EA714_RS05625	COG1535	isochorismatase
EA714_RS05640	COG1132	(ABC) transporter
EA714_RS05645	COG1132	(ABC) transporter
EA714_RS05650	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
EA714_RS05660	COG1169	isochorismate synthase
EA714_RS05675	COG3739	integral membrane protein
EA714_RS05695	COG0302	gtp cyclohydrolase
EA714_RS05705	COG1529	Aldehyde oxidase and xanthine dehydrogenase
EA714_RS05735	COG0308	aminopeptidase N
EA714_RS05740	COG0512	Glutamine amidotransferase of anthranilate synthase
EA714_RS05755	COG0174	glutamine synthetase
EA714_RS05765	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
EA714_RS05800	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
EA714_RS05805	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
EA714_RS05810	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
EA714_RS05830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
EA714_RS05835	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
EA714_RS05840	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
EA714_RS05855	COG1960	acyl-CoA dehydrogenase activity
EA714_RS05860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA714_RS05865	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA714_RS05875	COG2223	nitrite transmembrane transporter activity
EA714_RS05885	COG0024	Methionine aminopeptidase
EA714_RS05890	COG0052	Belongs to the universal ribosomal protein uS2 family
EA714_RS05905	COG2207	Transcriptional regulator
EA714_RS05930	COG2951	lytic endotransglycosylase activity
EA714_RS05935	COG0772	Belongs to the SEDS family
EA714_RS05950	COG0842	Transport permease protein
EA714_RS05955	COG1131	(ABC) transporter
EA714_RS06000	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_RS06025	COG4215	(ABC) transporter
EA714_RS06030	COG4160	amino acid transport
EA714_RS06035	COG4598	ABC transporter
EA714_RS06045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA714_RS06050	COG0826	peptidase U32
EA714_RS06055	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_RS06070	COG1720	tRNA m6t6A37 methyltransferase activity
EA714_RS06080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
EA714_RS06095	COG0642	Histidine kinase
EA714_RS06105	COG0494	nUDIX hydrolase
EA714_RS06115	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
EA714_RS06120	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
EA714_RS06125	COG3139	Protein of unknown function (DUF1315)
EA714_RS06130	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
EA714_RS06140	COG1301	dicarboxylic acid transport
EA714_RS06145	COG1960	acyl-CoA dehydrogenase activity
EA714_RS06150	COG2819	hydrolase of the alpha beta superfamily
EA714_RS06160	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
EA714_RS06170	COG2195	Cleaves the N-terminal amino acid of tripeptides
EA714_RS06175	COG1234	tRNA 3'-trailer cleavage
EA714_RS06205	COG2363	Small membrane protein
EA714_RS06225	COG0513	Belongs to the DEAD box helicase family
EA714_RS06235	COG0778	Nitroreductase
EA714_RS06265	COG1286	toxin biosynthetic process
EA714_RS06290	COG4783	chaperone-mediated protein folding
EA714_RS06295	COG1610	YqeY-like protein
EA714_RS06395	COG3111	PFAM Bacterial OB fold (BOF) protein
EA714_RS06420	COG3243	poly(R)-hydroxyalkanoic acid synthase
EA714_RS06425	COG0786	glutamate:sodium symporter activity
EA714_RS06435	COG2186	Transcriptional regulator
EA714_RS06485	COG0477	Major facilitator Superfamily
EA714_RS06515	COG2985	domain, Protein
EA714_RS06525	COG2995	paraquat-inducible protein a
EA714_RS06530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
EA714_RS06530	COG3008	intermembrane lipid transfer
EA714_RS06540	COG1794	racemase activity, acting on amino acids and derivatives
EA714_RS06570	COG1301	dicarboxylic acid transport
EA714_RS06580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA714_RS06585	COG2011	ABC-type metal ion transport system permease component
EA714_RS06590	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA714_RS06595	COG1464	Belongs to the NlpA lipoprotein family
EA714_RS06600	COG0151	Belongs to the GarS family
EA714_RS06605	COG0138	bifunctional purine biosynthesis protein purh
EA714_RS06610	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
EA714_RS06640	COG2308	Evidence 4 Homologs of previously reported genes of
EA714_RS06650	COG1305	Transglutaminase-like
EA714_RS06660	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
EA714_RS06665	COG0305	Participates in initiation and elongation during chromosome replication
EA714_RS06690	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
EA714_RS06700	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
EA714_RS06705	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
EA714_RS06730	COG0726	polysaccharide deacetylase
EA714_RS06730	COG1649	PFAM Uncharacterised BCR, COG1649
EA714_RS06735	COG1215	transferase activity, transferring glycosyl groups
EA714_RS06740	COG3658	cytochrome
EA714_RS06750	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA714_RS06770	COG0583	DNA-binding transcription factor activity
EA714_RS06790	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA714_RS06795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA714_RS06810	COG1960	acyl-CoA dehydrogenase activity
EA714_RS06815	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA714_RS06820	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_RS06845	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
EA714_RS06850	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
EA714_RS06860	COG2205	protein histidine kinase activity
EA714_RS06865	COG0745	RESPONSE REGULATOR receiver
EA714_RS06870	COG0174	glutamine synthetase
EA714_RS06890	COG0729	surface antigen
EA714_RS06920	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA714_RS06925	COG2814	Major facilitator Superfamily
EA714_RS06940	COG0583	DNA-binding transcription factor activity
EA714_RS06955	COG1187	pseudouridine synthase activity
EA714_RS06975	COG0802	atpase or kinase
EA714_RS06980	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
EA714_RS06990	COG1923	regulation of RNA biosynthetic process
EA714_RS06995	COG0697	spore germination
EA714_RS07010	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA714_RS07020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA714_RS07025	COG0519	Catalyzes the synthesis of GMP from XMP
EA714_RS07025	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA714_RS07030	COG4302	ethanolamine ammonia-lyase activity
EA714_RS07035	COG4303	Ethanolamine ammonia lyase large subunit
EA714_RS07040	COG0531	amino acid
EA714_RS07060	COG1454	alcohol dehydrogenase
EA714_RS07065	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA714_RS07075	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
EA714_RS07095	COG0308	aminopeptidase N
EA714_RS07105	COG4221	oxidoreductase activity
EA714_RS07115	COG1605	Chorismate mutase
EA714_RS07135	COG1309	transcriptional regulator
EA714_RS07145	COG0668	transmembrane transport
EA714_RS07175	COG4773	Receptor
EA714_RS07195	COG0488	(ABC) transporter
EA714_RS07200	COG0589	response to stress
EA714_RS07215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
EA714_RS07225	COG3135	benzoate transporter
EA714_RS07230	COG1522	sequence-specific DNA binding
EA714_RS07240	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
EA714_RS07245	COG0583	DNA-binding transcription factor activity
EA714_RS07255	COG0183	Belongs to the thiolase family
EA714_RS07265	COG2030	dehydratase
EA714_RS07270	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EA714_RS07285	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
EA714_RS07295	COG0824	Thioesterase
EA714_RS07300	COG1454	alcohol dehydrogenase
EA714_RS07310	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
EA714_RS07330	COG0069	glutamate synthase activity
EA714_RS07500	COG5410	chromosome segregation
EA714_RS07710	COG2814	Major facilitator Superfamily
EA714_RS07725	COG0511	ligase activity, forming carbon-carbon bonds
EA714_RS07745	COG1116	anion transmembrane transporter activity
EA714_RS07745	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA714_RS07750	COG0745	RESPONSE REGULATOR receiver
EA714_RS07760	COG2146	nitrite reductase [NAD(P)H] activity
EA714_RS07760	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_RS07765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_RS07770	COG0243	molybdopterin cofactor binding
EA714_RS07780	COG0243	molybdopterin cofactor binding
EA714_RS07785	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
EA714_RS07800	COG0521	Mo-molybdopterin cofactor biosynthetic process
EA714_RS07800	COG0315	cyclic pyranopterin monophosphate synthase activity
EA714_RS07805	COG0303	'Molybdopterin
EA714_RS07815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_RS07820	COG0697	spore germination
EA714_RS07840	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
EA714_RS07845	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA714_RS07905	COG2204	response regulator
EA714_RS07910	COG3852	Histidine kinase
EA714_RS07935	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
EA714_RS07940	COG0575	Belongs to the CDS family
EA714_RS07975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA714_RS07990	COG2137	regulation of response to DNA damage stimulus
EA714_RS08000	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
EA714_RS08005	COG1011	Hydrolase
EA714_RS08030	COG1522	sequence-specific DNA binding
EA714_RS08040	COG1113	amino acid transport
EA714_RS08055	COG0659	secondary active sulfate transmembrane transporter activity
EA714_RS08085	COG1132	(ABC) transporter
EA714_RS08135	COG0482	sulfurtransferase activity
EA714_RS08150	COG0488	(ABC) transporter
EA714_RS08155	COG3173	Aminoglycoside phosphotransferase
EA714_RS08165	COG2433	Pfam Transposase IS66
EA714_RS08210	COG5001	Diguanylate cyclase
EA714_RS08210	COG3300	MHYT domain
EA714_RS08230	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA714_RS08230	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
EA714_RS08230	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
EA714_RS08235	COG1105	Belongs to the carbohydrate kinase PfkB family
EA714_RS08240	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA714_RS08240	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
EA714_RS08270	COG0024	Methionine aminopeptidase
EA714_RS08275	COG0583	DNA-binding transcription factor activity
EA714_RS08285	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
EA714_RS08290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
EA714_RS08295	COG0517	IMP dehydrogenase activity
EA714_RS08295	COG0516	GMP reductase activity
EA714_RS08320	COG0552	protein localization to endoplasmic reticulum
EA714_RS08330	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
EA714_RS08345	COG4890	Cyd operon protein YbgT
EA714_RS08350	COG1294	oxidase, subunit
EA714_RS08365	COG1585	Membrane protein implicated in regulation of membrane protease activity
EA714_RS08375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
EA714_RS08380	COG4774	siderophore transport
EA714_RS08395	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
EA714_RS08400	COG0569	domain protein
EA714_RS08405	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
EA714_RS08435	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
EA714_RS08440	COG0542	response to heat
EA714_RS08465	COG1902	pentaerythritol trinitrate reductase activity
EA714_RS08465	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_RS08510	COG2323	membrane
EA714_RS08515	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
EA714_RS08525	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA714_RS08530	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA714_RS08535	COG0183	Belongs to the thiolase family
EA714_RS08540	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
EA714_RS08545	COG0596	Alpha beta hydrolase
EA714_RS08550	COG2271	Major facilitator Superfamily
EA714_RS08555	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA714_RS08560	COG3485	protocatechuate 3,4-dioxygenase
EA714_RS08565	COG3485	protocatechuate 3,4-dioxygenase
EA714_RS08570	COG0710	3-dehydroquinate dehydratase activity
EA714_RS08575	COG3420	alginic acid biosynthetic process
EA714_RS08580	COG3659	wide pore channel activity
EA714_RS08585	COG4993	Dehydrogenase
EA714_RS08595	COG2391	methyltransferase activity
EA714_RS08610	COG1414	Transcriptional regulator
EA714_RS08615	COG0583	DNA-binding transcription factor activity
EA714_RS08620	COG1960	acyl-CoA dehydrogenase activity
EA714_RS08645	COG2814	Major facilitator Superfamily
EA714_RS08655	COG0154	amidase activity
EA714_RS08675	COG4638	Rieske (2fe-2S)
EA714_RS08685	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS08695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_RS08705	COG3733	amine oxidase
EA714_RS08715	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS08725	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA714_RS08730	COG0183	Belongs to the thiolase family
EA714_RS08735	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA714_RS08740	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA714_RS08750	COG4829	muconolactone delta-isomerase
EA714_RS08755	COG4948	Mandelate Racemase Muconate Lactonizing
EA714_RS08760	COG0583	DNA-binding transcription factor activity
EA714_RS08770	COG2186	Transcriptional regulator
EA714_RS08790	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS08810	COG1960	acyl-CoA dehydrogenase activity
EA714_RS08815	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS08820	COG3829	transcription factor binding
EA714_RS08830	COG3162	membrane
EA714_RS08845	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS08860	COG0753	catalase activity
EA714_RS08885	COG1846	Transcriptional regulator
EA714_RS08890	COG1902	pentaerythritol trinitrate reductase activity
EA714_RS08890	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_RS08900	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
EA714_RS08930	COG1309	transcriptional regulator
EA714_RS08940	COG1335	isochorismatase
EA714_RS08950	COG0583	DNA-binding transcription factor activity
EA714_RS08960	COG0475	glutathione-regulated potassium exporter activity
EA714_RS08960	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA714_RS08970	COG1473	amidohydrolase
EA714_RS08985	COG2831	hemolysin activation secretion protein
EA714_RS08990	COG3210	domain, Protein
EA714_RS09020	COG2188	Transcriptional regulator
EA714_RS09035	COG0583	DNA-binding transcription factor activity
EA714_RS09065	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA714_RS09085	COG1566	PFAM secretion protein HlyD family protein
EA714_RS09100	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS09105	COG0129	dihydroxy-acid dehydratase activity
EA714_RS09115	COG0583	DNA-binding transcription factor activity
EA714_RS09120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
EA714_RS09130	COG2084	Dehydrogenase
EA714_RS09135	COG2207	Transcriptional regulator
EA714_RS09150	COG1064	alcohol dehydrogenase
EA714_RS09160	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
EA714_RS09165	COG1120	ATPase activity
EA714_RS09185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA714_RS09305	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
EA714_RS09360	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS09375	COG2207	Transcriptional regulator
EA714_RS09385	COG2205	protein histidine kinase activity
EA714_RS09390	COG0745	RESPONSE REGULATOR receiver
EA714_RS09395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_RS09400	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA714_RS09405	COG1538	Outer membrane efflux protein
EA714_RS09415	COG2072	flavoprotein involved in K transport
EA714_RS09435	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA714_RS09455	COG3539	Fimbrial protein
EA714_RS09485	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
EA714_RS09495	COG0753	catalase activity
EA714_RS09510	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
EA714_RS09575	COG3433	isochorismatase activity
EA714_RS09575	COG1535	isochorismatase
EA714_RS09580	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS09585	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
EA714_RS09590	COG4149	molybdate abc transporter
EA714_RS09595	COG0725	ABC transporter, periplasmic molybdate-binding protein
EA714_RS09605	COG4638	Rieske (2fe-2S)
EA714_RS09610	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA714_RS09615	COG0543	2 iron, 2 sulfur cluster binding
EA714_RS09615	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA714_RS09640	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS09655	COG2207	Transcriptional regulator
EA714_RS09665	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS09670	COG2610	gluconate transmembrane transporter activity
EA714_RS09680	COG0583	DNA-binding transcription factor activity
EA714_RS09690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA714_RS09695	COG2031	fatty acid transporter
EA714_RS09700	COG0183	Belongs to the thiolase family
EA714_RS09705	COG0583	DNA-binding transcription factor activity
EA714_RS09710	COG0583	DNA-binding transcription factor activity
EA714_RS09725	COG1027	Aspartate ammonia-lyase
EA714_RS09735	COG0477	Major facilitator Superfamily
EA714_RS09755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA714_RS09760	COG4521	taurine ABC transporter
EA714_RS09775	COG2188	Transcriptional regulator
EA714_RS09785	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
EA714_RS09790	COG1733	regulation of RNA biosynthetic process
EA714_RS09795	COG2207	Transcriptional regulator
EA714_RS09795	COG3708	Transcriptional regulator
EA714_RS09810	COG0730	response to heat
EA714_RS09820	COG3453	Protein conserved in bacteria
EA714_RS09820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA714_RS09830	COG3781	membrane
EA714_RS09835	COG1063	alcohol dehydrogenase
EA714_RS09845	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
EA714_RS09850	COG0508	dehydrogenase complex catalyzes the overall conversion of
EA714_RS09855	COG0022	dehydrogenase e1 component
EA714_RS09860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
EA714_RS09865	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
EA714_RS09880	COG3706	GGDEF domain
EA714_RS09895	COG0133	tryptophan synthase activity
EA714_RS09905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
EA714_RS09940	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
EA714_RS09965	COG2226	methyltransferase
EA714_RS10020	COG0842	Transport permease protein
EA714_RS10025	COG0842	Transport permease protein
EA714_RS10030	COG1131	(ABC) transporter
EA714_RS10045	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
EA714_RS10050	COG4773	Receptor
EA714_RS10070	COG0730	response to heat
EA714_RS10075	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
EA714_RS10095	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
EA714_RS10155	COG4264	IucA IucC family
EA714_RS10160	COG4264	IucA IucC family
EA714_RS10180	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
EA714_RS10195	COG1960	acyl-CoA dehydrogenase activity
EA714_RS10200	COG1960	acyl-CoA dehydrogenase activity
EA714_RS10205	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
EA714_RS10210	COG2207	Transcriptional regulator
EA714_RS10215	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA714_RS10220	COG0776	regulation of translation
EA714_RS10245	COG0822	iron-sulfur transferase activity
EA714_RS10250	COG0316	Belongs to the HesB IscA family
EA714_RS10280	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
EA714_RS10300	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
EA714_RS10305	COG0702	epimerase
EA714_RS10340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
EA714_RS10350	COG0339	signal peptide processing
EA714_RS10400	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
EA714_RS10405	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
EA714_RS10435	COG0776	regulation of translation
EA714_RS10500	COG0084	hydrolase, TatD family'
EA714_RS10520	COG1663	tetraacyldisaccharide 4'-kinase activity
EA714_RS10525	COG1132	(ABC) transporter
EA714_RS10535	COG0811	peptide transport
EA714_RS10540	COG1475	DNA binding
EA714_RS10545	COG1192	Involved in chromosome partitioning
EA714_RS10555	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
EA714_RS10570	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
EA714_RS10575	COG0191	fructose-bisphosphate aldolase activity
EA714_RS10595	COG0424	maF-like protein
EA714_RS10600	COG2850	peptidyl-arginine hydroxylation
EA714_RS10610	COG0640	Transcriptional regulator
EA714_RS10620	COG3619	membrane
EA714_RS10625	COG3122	Protein conserved in bacteria
EA714_RS10630	COG1132	(ABC) transporter
EA714_RS10650	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
EA714_RS10655	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
EA714_RS10665	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA714_RS10665	COG0506	proline dehydrogenase activity
EA714_RS10665	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
EA714_RS10670	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
EA714_RS10685	COG3698	Phosphodiester glycosidase
EA714_RS10695	COG2353	YceI-like domain
EA714_RS10705	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
EA714_RS10755	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
EA714_RS10755	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
EA714_RS10780	COG3539	Fimbrial protein
EA714_RS10785	COG3121	Chaperone
EA714_RS10815	COG0697	spore germination
EA714_RS10825	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA714_RS10835	COG0583	DNA-binding transcription factor activity
EA714_RS10855	COG1309	transcriptional regulator
EA714_RS10870	COG1522	sequence-specific DNA binding
EA714_RS10880	COG1126	abc transporter atp-binding protein
EA714_RS10885	COG0765	amino acid transport
EA714_RS10890	COG0765	amino acid transport
EA714_RS10920	COG1464	Belongs to the NlpA lipoprotein family
EA714_RS10930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
EA714_RS10935	COG2011	ABC-type metal ion transport system permease component
EA714_RS10940	COG0012	GTP binding
EA714_RS10965	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
EA714_RS11005	COG0386	Belongs to the glutathione peroxidase family
EA714_RS11015	COG0436	Aminotransferase
EA714_RS11055	COG3634	alkyl hydroperoxide reductase activity
EA714_RS11070	COG0583	DNA-binding transcription factor activity
EA714_RS11075	COG0798	PFAM Bile acid sodium symporter
EA714_RS11080	COG0640	Transcriptional regulator
EA714_RS11095	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
EA714_RS11105	COG0583	DNA-binding transcription factor activity
EA714_RS11115	COG1953	Uracil, thiamine, allantoin
EA714_RS11125	COG2175	clavaminate synthase activity
EA714_RS11130	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA714_RS11135	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
EA714_RS11140	COG4521	taurine ABC transporter
EA714_RS11160	COG0477	Major facilitator Superfamily
EA714_RS11185	COG1271	oxidase subunit
EA714_RS11190	COG1294	oxidase, subunit
EA714_RS11200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_RS11220	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
EA714_RS11240	COG3052	prosthetic group binding
EA714_RS11245	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
EA714_RS11255	COG2814	Major facilitator Superfamily
EA714_RS11275	COG1346	cytolysis
EA714_RS11285	COG0583	DNA-binding transcription factor activity
EA714_RS11290	COG0625	glutathione transferase activity
EA714_RS11295	COG0625	glutathione transferase activity
EA714_RS11300	COG0583	DNA-binding transcription factor activity
EA714_RS11315	COG1045	serine acetyltransferase
EA714_RS11320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
EA714_RS11325	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
EA714_RS11335	COG1280	lysine exporter protein (LysE YggA)
EA714_RS11350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA714_RS11355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA714_RS11360	COG1126	abc transporter atp-binding protein
EA714_RS11365	COG0765	amino acid transport
EA714_RS11370	COG0765	amino acid transport
EA714_RS11390	COG2205	protein histidine kinase activity
EA714_RS11390	COG0784	Response regulator, receiver
EA714_RS11410	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
EA714_RS11430	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS11475	COG0583	DNA-binding transcription factor activity
EA714_RS11495	COG0318	PFAM AMP-dependent synthetase and ligase
EA714_RS11500	COG1309	transcriptional regulator
EA714_RS11505	COG1960	acyl-CoA dehydrogenase activity
EA714_RS11510	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
EA714_RS11515	COG1024	Enoyl-CoA hydratase
EA714_RS11520	COG4770	biotin carboxylase activity
EA714_RS11530	COG0583	DNA-binding transcription factor activity
EA714_RS11545	COG1960	acyl-CoA dehydrogenase activity
EA714_RS11555	COG2814	Major facilitator Superfamily
EA714_RS11565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
EA714_RS11570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
EA714_RS11575	COG2814	Major facilitator Superfamily
EA714_RS11580	COG1960	acyl-CoA dehydrogenase activity
EA714_RS11585	COG1024	Enoyl-CoA hydratase
EA714_RS11590	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS11595	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA714_RS11600	COG0183	Belongs to the thiolase family
EA714_RS11610	COG2814	Major facilitator Superfamily
EA714_RS11620	COG1024	Enoyl-CoA hydratase
EA714_RS11635	COG1960	acyl-CoA dehydrogenase activity
EA714_RS11640	COG2814	Major facilitator Superfamily
EA714_RS11645	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
EA714_RS11650	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
EA714_RS11665	COG3842	ATPase activity
EA714_RS11670	COG1840	ABC-type Fe3 transport system, periplasmic component
EA714_RS11680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_RS11685	COG1414	Transcriptional regulator
EA714_RS11695	COG0583	DNA-binding transcription factor activity
EA714_RS11700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
EA714_RS11705	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS11715	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
EA714_RS11725	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS11730	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA714_RS11735	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_RS11740	COG2267	carboxylic ester hydrolase activity
EA714_RS11760	COG3038	cytochrome b561
EA714_RS11765	COG0753	catalase activity
EA714_RS11805	COG2050	protein possibly involved in aromatic compounds catabolism
EA714_RS11815	COG3327	negative regulation of DNA-templated transcription, initiation
EA714_RS11820	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
EA714_RS11825	COG0183	Belongs to the thiolase family
EA714_RS11830	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA714_RS11835	COG1024	Enoyl-CoA hydratase
EA714_RS11840	COG1024	Enoyl-CoA hydratase
EA714_RS11845	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
EA714_RS11850	COG2151	metal-sulfur cluster biosynthetic enzyme
EA714_RS11855	COG3396	Phenylacetate-CoA oxygenase
EA714_RS11860	COG3460	Phenylacetate-CoA oxygenase
EA714_RS11865	COG3396	Phenylacetate-CoA oxygenase
EA714_RS11870	COG2030	dehydratase
EA714_RS11870	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS11875	COG1760	l-serine dehydratase
EA714_RS11880	COG0531	amino acid
EA714_RS11885	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS11900	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_RS11910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
EA714_RS11930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA714_RS11945	COG0789	Transcriptional regulator
EA714_RS11960	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
EA714_RS11975	COG2807	transmembrane transport
EA714_RS11980	COG0590	tRNA wobble adenosine to inosine editing
EA714_RS12100	COG1116	anion transmembrane transporter activity
EA714_RS12105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
EA714_RS12115	COG0864	Transcriptional regulator
EA714_RS12135	COG2249	NAD(P)H dehydrogenase (quinone) activity
EA714_RS12140	COG0439	Biotin carboxylase
EA714_RS12155	COG1063	alcohol dehydrogenase
EA714_RS12165	COG1309	transcriptional regulator
EA714_RS12190	COG0038	chloride channel
EA714_RS12195	COG4770	biotin carboxylase activity
EA714_RS12215	COG1914	H( )-stimulated, divalent metal cation uptake system
EA714_RS12220	COG0583	DNA-binding transcription factor activity
EA714_RS12275	COG1250	3-hydroxyacyl-CoA dehydrogenase
EA714_RS12295	COG2814	Major facilitator Superfamily
EA714_RS12310	COG1560	Kdo2-lipid A biosynthetic process
EA714_RS12320	COG5006	permease, DMT superfamily
EA714_RS12325	COG1522	sequence-specific DNA binding
EA714_RS12340	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
EA714_RS12350	COG4122	O-methyltransferase activity
EA714_RS12380	COG1538	Outer membrane efflux protein
EA714_RS12385	COG1137	ATPase activity
EA714_RS12390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
EA714_RS12400	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
EA714_RS12405	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
EA714_RS12405	COG0517	IMP dehydrogenase activity
EA714_RS12445	COG2814	Major facilitator Superfamily
EA714_RS12485	COG1278	Cold shock
EA714_RS12490	COG1280	lysine exporter protein (LysE YggA)
EA714_RS12525	COG1570	exodeoxyribonuclease VII activity
EA714_RS12580	COG0583	DNA-binding transcription factor activity
EA714_RS12585	COG4638	Rieske (2fe-2S)
EA714_RS12590	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
EA714_RS12595	COG0543	2 iron, 2 sulfur cluster binding
EA714_RS12595	COG0633	Ferredoxin
EA714_RS12600	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS12605	COG3135	benzoate transporter
EA714_RS12610	COG2814	Major facilitator Superfamily
EA714_RS12625	COG1643	Atp-dependent helicase
EA714_RS12630	COG0450	alkyl hydroperoxide reductase
EA714_RS12640	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
EA714_RS12650	COG3634	alkyl hydroperoxide reductase activity
EA714_RS12670	COG0220	tRNA (guanine-N7-)-methyltransferase activity
EA714_RS12675	COG0625	glutathione transferase activity
EA714_RS12685	COG2885	chlorophyll binding
EA714_RS12720	COG0542	response to heat
EA714_RS12735	COG1765	OsmC-like protein
EA714_RS12745	COG0667	Aldo Keto reductase
EA714_RS12760	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
EA714_RS12770	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
EA714_RS12780	COG0527	aspartate kinase activity
EA714_RS12790	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
EA714_RS12800	COG3038	cytochrome b561
EA714_RS12805	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
EA714_RS12845	COG4269	membrane
EA714_RS12860	COG1902	pentaerythritol trinitrate reductase activity
EA714_RS12860	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_RS12870	COG5001	Diguanylate cyclase
EA714_RS12870	COG4251	negative regulation of phosphorylation
EA714_RS12870	COG3706	GGDEF domain
EA714_RS12870	COG2203	Gaf domain
EA714_RS12880	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA714_RS12900	COG4172	Belongs to the ABC transporter superfamily
EA714_RS12905	COG4239	(ABC) transporter, permease
EA714_RS12910	COG4174	ABC transporter (Permease)
EA714_RS12920	COG0741	lytic transglycosylase activity
EA714_RS12920	COG1388	LysM domain
EA714_RS12920	COG0741	lytic transglycosylase activity
EA714_RS12920	COG1388	LysM domain
EA714_RS12925	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
EA714_RS12965	COG0583	DNA-binding transcription factor activity
EA714_RS12970	COG1279	arginine transmembrane transporter activity
EA714_RS12990	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_RS12995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_RS13000	COG0006	proline dipeptidase activity
EA714_RS13035	COG2194	sulfuric ester hydrolase activity
EA714_RS13080	COG0739	heme binding
EA714_RS13405	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
EA714_RS13430	COG3384	dioxygenase
EA714_RS13440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
EA714_RS13445	COG2878	Part of a membrane complex involved in electron transport
EA714_RS13450	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
EA714_RS13475	COG0768	penicillin binding
EA714_RS13480	COG0742	ribosomal rna small subunit methyltransferase
EA714_RS13495	COG0830	nickel cation binding
EA714_RS13505	COG0804	urea catabolic process
EA714_RS13545	COG1253	flavin adenine dinucleotide binding
EA714_RS13555	COG2851	Citrate transporter
EA714_RS13605	COG1773	rubredoxin
EA714_RS13610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
EA714_RS13620	COG0583	DNA-binding transcription factor activity
EA714_RS13645	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
EA714_RS13650	COG4181	ATPase activity
EA714_RS13695	COG1262	PFAM Formylglycine-generating sulfatase enzyme
EA714_RS13715	COG0306	phosphate transporter
EA714_RS13725	COG3958	Transketolase
EA714_RS13730	COG3959	Transketolase, thiamine diphosphate binding domain
EA714_RS13735	COG2271	Major facilitator Superfamily
EA714_RS13740	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS13745	COG0583	DNA-binding transcription factor activity
EA714_RS13765	COG2223	nitrite transmembrane transporter activity
EA714_RS13770	COG2207	Transcriptional regulator
EA714_RS13775	COG2066	Belongs to the glutaminase family
EA714_RS13780	COG0242	peptide deformylase activity
EA714_RS13785	COG0477	Major facilitator Superfamily
EA714_RS13795	COG0028	Belongs to the TPP enzyme family
EA714_RS13810	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS13815	COG2267	carboxylic ester hydrolase activity
EA714_RS13825	COG2271	Major facilitator Superfamily
EA714_RS13830	COG0446	pyridine nucleotide-disulphide oxidoreductase
EA714_RS13840	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS13860	COG1414	Transcriptional regulator
EA714_RS13875	COG1024	Enoyl-CoA hydratase
EA714_RS13885	COG1215	transferase activity, transferring glycosyl groups
EA714_RS13890	COG1649	PFAM Uncharacterised BCR, COG1649
EA714_RS13890	COG0726	polysaccharide deacetylase
EA714_RS13900	COG4681	YaeQ
EA714_RS13910	COG0523	cobalamin synthesis protein
EA714_RS13920	COG1607	acyl-coa hydrolase
EA714_RS13930	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_RS13935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
EA714_RS13940	COG1309	transcriptional regulator
EA714_RS13965	COG2040	homocysteine
EA714_RS13970	COG0531	amino acid
EA714_RS14025	COG1595	DNA-templated transcription, initiation
EA714_RS14035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA714_RS14040	COG0477	Major facilitator Superfamily
EA714_RS14165	COG0582	viral genome integration into host DNA
EA714_RS14175	COG0405	Gamma-glutamyltransferase
EA714_RS14180	COG2814	Major facilitator Superfamily
EA714_RS14190	COG2050	protein possibly involved in aromatic compounds catabolism
EA714_RS14205	COG1090	epimerase
EA714_RS14225	COG0420	3'-5' exonuclease activity
EA714_RS14250	COG0735	belongs to the Fur family
EA714_RS14255	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
EA714_RS14280	COG0121	glutamine amidotransferase
EA714_RS14295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA714_RS14305	COG0210	DNA helicase
EA714_RS14310	COG2885	chlorophyll binding
EA714_RS14315	COG0204	Acyl-transferase
EA714_RS14330	COG2894	cell division
EA714_RS14350	COG1280	lysine exporter protein (LysE YggA)
EA714_RS14355	COG1674	ftsk spoiiie
EA714_RS14355	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
EA714_RS14360	COG0492	ferredoxin-NADP+ reductase activity
EA714_RS14365	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
EA714_RS14375	COG0456	acetyltransferase
EA714_RS14420	COG1981	membrane
EA714_RS14435	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
EA714_RS14435	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA714_RS14455	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS14465	COG0657	acetylesterase activity
EA714_RS14475	COG0473	3-isopropylmalate dehydrogenase activity
EA714_RS14480	COG0583	DNA-binding transcription factor activity
EA714_RS14500	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
EA714_RS14525	COG0564	pseudouridine synthase activity
EA714_RS14535	COG0358	DNA primase activity
EA714_RS14550	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
EA714_RS14580	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
EA714_RS14610	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
EA714_RS14620	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
EA714_RS14620	COG0351	phosphomethylpyrimidine kinase
EA714_RS14620	COG0352	thiamine-phosphate diphosphorylase activity
EA714_RS14625	COG1652	LysM domain
EA714_RS14650	COG1399	metal-binding, possibly nucleic acid-binding protein
EA714_RS14655	COG3101	peptidyl-lysine hydroxylation
EA714_RS14660	COG0009	L-threonylcarbamoyladenylate synthase
EA714_RS14665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
EA714_RS14670	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
EA714_RS14685	COG4106	trans-aconitate 2-methyltransferase activity
EA714_RS14700	COG2226	methyltransferase
EA714_RS14700	COG0596	Alpha beta hydrolase
EA714_RS14700	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA714_RS14705	COG1877	trehalose-phosphatase activity
EA714_RS14710	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
EA714_RS14715	COG2223	nitrite transmembrane transporter activity
EA714_RS14735	COG1196	nuclear chromosome segregation
EA714_RS14745	COG0730	response to heat
EA714_RS14760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
EA714_RS14770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA714_RS14830	COG0489	protein tyrosine kinase activity
EA714_RS14840	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA714_RS14840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA714_RS14870	COG2515	1-aminocyclopropane-1-carboxylate deaminase
EA714_RS14875	COG2081	HI0933 family
EA714_RS14885	COG0668	transmembrane transport
EA714_RS14905	COG0583	DNA-binding transcription factor activity
EA714_RS14925	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
EA714_RS14930	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA714_RS14960	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
EA714_RS15000	COG0745	RESPONSE REGULATOR receiver
EA714_RS15020	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
EA714_RS15030	COG2205	protein histidine kinase activity
EA714_RS15100	COG4993	Dehydrogenase
EA714_RS15120	COG0384	phenazine biosynthesis protein PhzF
EA714_RS15150	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
EA714_RS15165	COG0583	DNA-binding transcription factor activity
EA714_RS15195	COG0583	DNA-binding transcription factor activity
EA714_RS15215	COG0583	DNA-binding transcription factor activity
EA714_RS15220	COG1053	succinate dehydrogenase
EA714_RS15230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
EA714_RS15235	COG2814	Major facilitator Superfamily
EA714_RS15240	COG1960	acyl-CoA dehydrogenase activity
EA714_RS15245	COG0583	DNA-binding transcription factor activity
EA714_RS15250	COG1063	alcohol dehydrogenase
EA714_RS15280	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
EA714_RS15285	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
EA714_RS15290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA714_RS15305	COG3667	copper resistance
EA714_RS15310	COG2132	Multicopper oxidase
EA714_RS15320	COG0561	phosphatase activity
EA714_RS15325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
EA714_RS15350	COG1214	PFAM Peptidase M22, glycoprotease
EA714_RS15400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
EA714_RS15410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
EA714_RS15415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
EA714_RS15420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
EA714_RS15480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
EA714_RS15490	COG1846	Transcriptional regulator
EA714_RS15495	COG1764	response to oxidative stress
EA714_RS15535	COG0037	tRNA processing
EA714_RS15545	COG0248	Ppx GppA phosphatase
EA714_RS15575	COG0072	phenylalanine-tRNA ligase activity
EA714_RS15615	COG1238	metal cluster binding
EA714_RS15620	COG0625	glutathione transferase activity
EA714_RS15640	COG0318	PFAM AMP-dependent synthetase and ligase
EA714_RS15645	COG3028	Belongs to the UPF0307 family
EA714_RS15650	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
EA714_RS15670	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
EA714_RS15675	COG0617	tRNA 3'-terminal CCA addition
EA714_RS15680	COG1555	photosystem II stabilization
EA714_RS15685	COG3956	TIGRFAM MazG family protein
EA714_RS15695	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
EA714_RS15715	COG0784	Response regulator, receiver
EA714_RS15715	COG5002	protein histidine kinase activity
EA714_RS15715	COG2205	protein histidine kinase activity
EA714_RS15720	COG1024	Enoyl-CoA hydratase
EA714_RS15725	COG2084	Dehydrogenase
EA714_RS15730	COG3622	Belongs to the hyi family
EA714_RS15760	COG0697	spore germination
EA714_RS15770	COG2814	Major facilitator Superfamily
EA714_RS15775	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
EA714_RS15785	COG0583	DNA-binding transcription factor activity
EA714_RS15795	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
EA714_RS15810	COG0084	hydrolase, TatD family'
EA714_RS15825	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
EA714_RS15860	COG0440	acetolactate synthase activity
EA714_RS15865	COG0028	Belongs to the TPP enzyme family
EA714_RS15890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
EA714_RS15895	COG0577	efflux transmembrane transporter activity
EA714_RS15895	COG1136	(ABC) transporter
EA714_RS15900	COG1538	Outer membrane efflux protein
EA714_RS15915	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
EA714_RS15920	COG1162	GTPase activity
EA714_RS15930	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
EA714_RS15950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
EA714_RS15955	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS15995	COG2986	histidine ammonia-lyase
EA714_RS16010	COG0318	PFAM AMP-dependent synthetase and ligase
EA714_RS16020	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA714_RS16065	COG1426	Protein conserved in bacteria
EA714_RS16100	COG0793	Belongs to the peptidase S41A family
EA714_RS16115	COG2267	carboxylic ester hydrolase activity
EA714_RS16125	COG1012	belongs to the aldehyde dehydrogenase family
EA714_RS16130	COG3265	gluconokinase activity
EA714_RS16140	COG0800	Aldolase
EA714_RS16150	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
EA714_RS16155	COG0280	phosphate acetyltransferase
EA714_RS16155	COG0857	belongs to the CobB CobQ family
EA714_RS16160	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
EA714_RS16160	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
EA714_RS16180	COG0740	serine-type endopeptidase activity
EA714_RS16190	COG4774	siderophore transport
EA714_RS16200	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
EA714_RS16210	COG2813	Specifically methylates the guanine in position
EA714_RS16210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
EA714_RS16310	COG0788	formyltetrahydrofolate deformylase activity
EA714_RS16335	COG4651	solute:proton antiporter activity
EA714_RS16335	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA714_RS16355	COG0724	RNA recognition motif
EA714_RS16360	COG0210	DNA helicase
EA714_RS16385	COG1733	regulation of RNA biosynthetic process
EA714_RS16395	COG2900	Belongs to the SlyX family
EA714_RS16400	COG0488	(ABC) transporter
EA714_RS16405	COG1280	lysine exporter protein (LysE YggA)
EA714_RS16410	COG1560	Kdo2-lipid A biosynthetic process
EA714_RS16420	COG1301	dicarboxylic acid transport
EA714_RS16475	COG0473	3-isopropylmalate dehydrogenase activity
EA714_RS16540	COG0583	DNA-binding transcription factor activity
EA714_RS16550	COG0625	glutathione transferase activity
EA714_RS16555	COG2378	regulation of single-species biofilm formation
EA714_RS16560	COG0546	phosphoglycolate phosphatase activity
EA714_RS16575	COG1530	ribonuclease E activity
EA714_RS16580	COG0318	PFAM AMP-dependent synthetase and ligase
EA714_RS16595	COG0583	DNA-binding transcription factor activity
EA714_RS16600	COG4221	oxidoreductase activity
EA714_RS16605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
EA714_RS16615	COG0534	Mate efflux family protein
EA714_RS16630	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
EA714_RS16670	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
EA714_RS16675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
EA714_RS16690	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
EA714_RS16700	COG0644	oxidoreductase
EA714_RS16700	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
EA714_RS16705	COG0425	Belongs to the sulfur carrier protein TusA family
EA714_RS16710	COG4535	Mg2 and Co2 transporter CorC
EA714_RS16720	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
EA714_RS16740	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
EA714_RS16745	COG0475	glutathione-regulated potassium exporter activity
EA714_RS16745	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
EA714_RS16750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
EA714_RS16760	COG0484	heat shock protein binding
EA714_RS16765	COG0789	Transcriptional regulator
EA714_RS16770	COG0598	Magnesium transport protein CorA
EA714_RS16785	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
EA714_RS16790	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
EA714_RS16795	COG1074	ATP-dependent DNA helicase activity
EA714_RS16800	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
EA714_RS16820	COG2226	methyltransferase
EA714_RS16835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
EA714_RS16840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
EA714_RS16855	COG2111	Na H antiporter
EA714_RS16855	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
EA714_RS16860	COG1006	Multisubunit Na H antiporter MnhC subunit
EA714_RS16865	COG0651	ATP synthesis coupled electron transport
EA714_RS16870	COG1863	multisubunit Na H antiporter MnhE subunit
EA714_RS16875	COG2212	antiporter activity
EA714_RS16880	COG1320	monovalent cation:proton antiporter activity
EA714_RS16895	COG0195	Participates in both transcription termination and antitermination
EA714_RS16945	COG0237	dephospho-CoA kinase activity
EA714_RS16955	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
EA714_RS16970	COG0497	DNA recombination
EA714_RS16980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
EA714_RS17010	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
EA714_RS17010	COG2169	Transcriptional regulator
EA714_RS17015	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
EA714_RS17085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
EA714_RS17100	COG0326	Molecular chaperone. Has ATPase activity
EA714_RS17115	COG2056	Na+-H+ antiporter family
EA714_RS17120	COG0596	Alpha beta hydrolase
EA714_RS17215	COG0546	phosphoglycolate phosphatase activity
EA714_RS17220	COG1716	ATPase activity
EA714_RS17265	COG0181	hydroxymethylbilane synthase activity
EA714_RS17275	COG3275	phosphorelay sensor kinase activity
EA714_RS17295	COG1538	Outer membrane efflux protein
EA714_RS17300	COG0697	spore germination
EA714_RS17325	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
EA714_RS17330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
EA714_RS17335	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
EA714_RS17340	COG0772	Belongs to the SEDS family
EA714_RS17365	COG4974	Belongs to the 'phage' integrase family
EA714_RS17370	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA714_RS17380	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
EA714_RS17390	COG2197	response regulator
EA714_RS17405	COG0793	Belongs to the peptidase S41A family
EA714_RS17410	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
EA714_RS17415	COG0795	lipopolysaccharide-transporting ATPase activity
EA714_RS17455	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA714_RS17455	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
EA714_RS17465	COG0004	ammonium transporteR
EA714_RS17470	COG0347	Belongs to the P(II) protein family
EA714_RS17480	COG0606	chelatase, subunit chli
EA714_RS17535	COG0659	secondary active sulfate transmembrane transporter activity
EA714_RS17540	COG0589	response to stress
EA714_RS17590	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA714_RS17640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
EA714_RS17670	COG0659	secondary active sulfate transmembrane transporter activity
EA714_RS17675	COG0589	response to stress
EA714_RS17705	COG0606	chelatase, subunit chli
EA714_RS17710	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
EA714_RS17720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
EA714_RS17735	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
EA714_RS17750	COG0318	PFAM AMP-dependent synthetase and ligase
EA714_RS17760	COG0477	Major facilitator Superfamily
EA714_RS17765	COG2860	membrane
EA714_RS17775	COG1253	flavin adenine dinucleotide binding
EA714_RS17795	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
EA714_RS17830	COG0655	NAD(P)H dehydrogenase (quinone) activity
EA714_RS17840	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
EA714_RS17875	COG1309	transcriptional regulator
EA714_RS17910	COG0758	DNA mediated transformation
EA714_RS17920	COG0697	spore germination
EA714_RS17925	COG1309	transcriptional regulator
EA714_RS17940	COG0386	Belongs to the glutathione peroxidase family
EA714_RS18005	COG1121	(ABC) transporter
EA714_RS18010	COG1108	ABC-type Mn2 Zn2 transport systems permease components
EA714_RS18015	COG1280	lysine exporter protein (LysE YggA)
EA714_RS18020	COG2837	iron assimilation
EA714_RS18030	COG0281	malic enzyme
EA714_RS18075	COG0518	GMP synthase (glutamine-hydrolyzing) activity
EA714_RS18075	COG0519	Catalyzes the synthesis of GMP from XMP
EA714_RS18080	COG4399	Belongs to the UPF0754 family
EA714_RS18085	COG2259	Doxx family
EA714_RS18090	COG0586	Pfam SNARE associated Golgi protein
EA714_RS18105	COG1192	Involved in chromosome partitioning
EA714_RS18115	COG0271	Belongs to the BolA IbaG family
EA714_RS18135	COG2267	carboxylic ester hydrolase activity
EA714_RS18155	COG3321	synthase
EA714_RS18155	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
EA714_RS18155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
EA714_RS18155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
EA714_RS18160	COG1960	acyl-CoA dehydrogenase activity
EA714_RS18170	COG2197	response regulator
EA714_RS18180	COG3916	Acyl-homoserine-lactone synthase
EA714_RS18185	COG0477	Major facilitator Superfamily
EA714_RS18190	COG1024	Enoyl-CoA hydratase
EA714_RS18195	COG1024	Enoyl-CoA hydratase
EA714_RS18200	COG1960	acyl-CoA dehydrogenase activity
EA714_RS18205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
EA714_RS18225	COG1113	amino acid transport
EA714_RS18230	COG1113	amino acid transport
EA714_RS18235	COG0251	oxidation-reduction process
EA714_RS18275	COG0564	pseudouridine synthase activity
EA714_RS18340	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
EA714_RS18355	COG1802	Transcriptional regulator
EA714_RS18365	COG1448	Aminotransferase
EA714_RS18370	COG0277	FAD linked oxidase domain protein
EA714_RS18380	COG2186	Transcriptional regulator
EA714_RS18390	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
EA714_RS18395	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
EA714_RS18410	COG1210	Utp--glucose-1-phosphate uridylyltransferase
EA714_RS18420	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
EA714_RS18430	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
EA714_RS18435	COG0438	transferase activity, transferring glycosyl groups
EA714_RS18455	COG1216	Glycosyl transferase, family 2
EA714_RS18460	COG5039	Polysaccharide pyruvyl transferase
EA714_RS18470	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
EA714_RS18475	COG1596	polysaccharide export
EA714_RS18500	COG0728	peptidoglycan biosynthetic process
EA714_RS18505	COG3023	N-Acetylmuramoyl-L-alanine amidase
EA714_RS18560	COG0546	phosphoglycolate phosphatase activity
EA714_RS18565	COG1028	Short-chain dehydrogenase reductase Sdr
EA714_RS18585	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA714_RS18590	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
EA714_RS18595	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
EA714_RS18600	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
EA714_RS18605	COG1116	anion transmembrane transporter activity
EA714_RS18610	COG1309	transcriptional regulator
EA714_RS18615	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
EA714_RS18625	COG0196	riboflavin kinase activity
EA714_RS18630	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
EA714_RS18640	COG1047	Peptidyl-prolyl cis-trans
EA714_RS18680	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
EA714_RS18685	COG0657	acetylesterase activity
EA714_RS18735	COG2951	lytic endotransglycosylase activity
EA714_RS18740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
EA714_RS18760	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
EA714_RS18770	COG0671	phosphoesterase, PA-phosphatase related
EA714_RS18775	COG0861	Integral membrane protein TerC family
EA714_RS18785	COG0754	glutathionylspermidine amidase activity
EA714_RS18795	COG0402	S-adenosylhomocysteine deaminase activity
EA714_RS18810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
EA714_RS18815	COG1230	cation diffusion facilitator family transporter
EA714_RS18830	COG0706	membrane insertase activity