locus-tag	class	description
KQ254_RS00020	COG0440	acetolactate synthase activity
KQ254_RS00025	COG0028	Belongs to the TPP enzyme family
KQ254_RS00050	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_RS00055	COG0577	efflux transmembrane transporter activity
KQ254_RS00055	COG1136	(ABC) transporter
KQ254_RS00060	COG1538	Outer membrane efflux protein
KQ254_RS00075	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KQ254_RS00080	COG1162	GTPase activity
KQ254_RS00090	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KQ254_RS00130	COG1426	Protein conserved in bacteria
KQ254_RS00165	COG0793	Belongs to the peptidase S41A family
KQ254_RS00180	COG2267	carboxylic ester hydrolase activity
KQ254_RS00190	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS00195	COG3265	gluconokinase activity
KQ254_RS00205	COG0800	Aldolase
KQ254_RS00215	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KQ254_RS00220	COG0857	belongs to the CobB CobQ family
KQ254_RS00220	COG0280	phosphate acetyltransferase
KQ254_RS00225	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KQ254_RS00225	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KQ254_RS00245	COG0740	serine-type endopeptidase activity
KQ254_RS00255	COG4774	siderophore transport
KQ254_RS00265	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQ254_RS00275	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ254_RS00275	COG2813	Specifically methylates the guanine in position
KQ254_RS00375	COG0788	formyltetrahydrofolate deformylase activity
KQ254_RS00400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ254_RS00400	COG4651	solute:proton antiporter activity
KQ254_RS00420	COG0724	RNA recognition motif
KQ254_RS00425	COG0210	DNA helicase
KQ254_RS00450	COG1733	regulation of RNA biosynthetic process
KQ254_RS00460	COG2900	Belongs to the SlyX family
KQ254_RS00465	COG0488	(ABC) transporter
KQ254_RS00470	COG1280	lysine exporter protein (LysE YggA)
KQ254_RS00475	COG1560	Kdo2-lipid A biosynthetic process
KQ254_RS00485	COG1301	dicarboxylic acid transport
KQ254_RS00540	COG0473	3-isopropylmalate dehydrogenase activity
KQ254_RS00595	COG0583	DNA-binding transcription factor activity
KQ254_RS00605	COG0625	glutathione transferase activity
KQ254_RS00610	COG2378	regulation of single-species biofilm formation
KQ254_RS00615	COG0546	phosphoglycolate phosphatase activity
KQ254_RS00625	COG1530	ribonuclease E activity
KQ254_RS00630	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_RS00645	COG0583	DNA-binding transcription factor activity
KQ254_RS00650	COG4221	oxidoreductase activity
KQ254_RS00655	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KQ254_RS00665	COG0534	Mate efflux family protein
KQ254_RS00680	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KQ254_RS00710	COG0493	'glutamate synthase
KQ254_RS00710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ254_RS00720	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KQ254_RS00725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ254_RS00740	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ254_RS00750	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KQ254_RS00750	COG0644	oxidoreductase
KQ254_RS00755	COG0425	Belongs to the sulfur carrier protein TusA family
KQ254_RS00760	COG4535	Mg2 and Co2 transporter CorC
KQ254_RS00770	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ254_RS00790	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KQ254_RS00795	COG0475	glutathione-regulated potassium exporter activity
KQ254_RS00795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ254_RS00810	COG0484	heat shock protein binding
KQ254_RS00815	COG0789	Transcriptional regulator
KQ254_RS00820	COG0598	Magnesium transport protein CorA
KQ254_RS00835	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ254_RS00840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQ254_RS00845	COG1074	ATP-dependent DNA helicase activity
KQ254_RS00850	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KQ254_RS00870	COG2226	methyltransferase
KQ254_RS00885	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_RS00890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KQ254_RS00905	COG2111	Na H antiporter
KQ254_RS00905	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQ254_RS00910	COG1006	Multisubunit Na H antiporter MnhC subunit
KQ254_RS00915	COG0651	ATP synthesis coupled electron transport
KQ254_RS00920	COG1863	multisubunit Na H antiporter MnhE subunit
KQ254_RS00925	COG2212	antiporter activity
KQ254_RS00930	COG1320	monovalent cation:proton antiporter activity
KQ254_RS00945	COG0195	Participates in both transcription termination and antitermination
KQ254_RS00995	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KQ254_RS01000	COG0237	dephospho-CoA kinase activity
KQ254_RS01010	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ254_RS01025	COG0497	DNA recombination
KQ254_RS01035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KQ254_RS01065	COG2169	Transcriptional regulator
KQ254_RS01065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ254_RS01070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KQ254_RS01125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KQ254_RS01140	COG0326	Molecular chaperone. Has ATPase activity
KQ254_RS01155	COG2056	Na+-H+ antiporter family
KQ254_RS01255	COG0546	phosphoglycolate phosphatase activity
KQ254_RS01260	COG1716	ATPase activity
KQ254_RS01305	COG0181	hydroxymethylbilane synthase activity
KQ254_RS01315	COG3275	phosphorelay sensor kinase activity
KQ254_RS01335	COG1538	Outer membrane efflux protein
KQ254_RS01345	COG0697	spore germination
KQ254_RS01370	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KQ254_RS01375	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KQ254_RS01380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ254_RS01385	COG0772	Belongs to the SEDS family
KQ254_RS01410	COG4974	Belongs to the 'phage' integrase family
KQ254_RS01415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ254_RS01425	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KQ254_RS01435	COG2197	response regulator
KQ254_RS01450	COG0793	Belongs to the peptidase S41A family
KQ254_RS01455	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KQ254_RS01460	COG0795	lipopolysaccharide-transporting ATPase activity
KQ254_RS01500	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ254_RS01500	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ254_RS01510	COG0004	ammonium transporteR
KQ254_RS01515	COG0347	Belongs to the P(II) protein family
KQ254_RS01590	COG0235	Class ii aldolase
KQ254_RS01595	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ254_RS01615	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KQ254_RS01630	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_RS01640	COG0477	Major facilitator Superfamily
KQ254_RS01645	COG2860	membrane
KQ254_RS01655	COG1253	flavin adenine dinucleotide binding
KQ254_RS01665	COG2814	Major facilitator Superfamily
KQ254_RS01675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ254_RS01715	COG0655	NAD(P)H dehydrogenase (quinone) activity
KQ254_RS01725	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KQ254_RS01795	COG0758	DNA mediated transformation
KQ254_RS01805	COG0697	spore germination
KQ254_RS01810	COG1309	transcriptional regulator
KQ254_RS01825	COG0386	Belongs to the glutathione peroxidase family
KQ254_RS01895	COG1121	(ABC) transporter
KQ254_RS01900	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KQ254_RS01905	COG1280	lysine exporter protein (LysE YggA)
KQ254_RS01910	COG2837	iron assimilation
KQ254_RS01920	COG0281	malic enzyme
KQ254_RS01965	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ254_RS01965	COG0519	Catalyzes the synthesis of GMP from XMP
KQ254_RS01970	COG4399	Belongs to the UPF0754 family
KQ254_RS01975	COG2259	Doxx family
KQ254_RS01980	COG0586	Pfam SNARE associated Golgi protein
KQ254_RS01995	COG1192	Involved in chromosome partitioning
KQ254_RS02005	COG0271	Belongs to the BolA IbaG family
KQ254_RS02045	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KQ254_RS02045	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KQ254_RS02045	COG3321	synthase
KQ254_RS02045	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KQ254_RS02050	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS02060	COG2197	response regulator
KQ254_RS02070	COG3916	Acyl-homoserine-lactone synthase
KQ254_RS02075	COG0477	Major facilitator Superfamily
KQ254_RS02080	COG1024	Enoyl-CoA hydratase
KQ254_RS02085	COG1024	Enoyl-CoA hydratase
KQ254_RS02090	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS02095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ254_RS02115	COG1113	amino acid transport
KQ254_RS02120	COG1113	amino acid transport
KQ254_RS02125	COG0251	oxidation-reduction process
KQ254_RS02165	COG0564	pseudouridine synthase activity
KQ254_RS02210	COG1051	belongs to the nudix hydrolase family
KQ254_RS02230	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KQ254_RS02245	COG1802	Transcriptional regulator
KQ254_RS02255	COG1448	Aminotransferase
KQ254_RS02260	COG0277	FAD linked oxidase domain protein
KQ254_RS02270	COG2186	Transcriptional regulator
KQ254_RS02280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ254_RS02285	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ254_RS02300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KQ254_RS02305	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KQ254_RS02310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KQ254_RS02365	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KQ254_RS02370	COG1596	polysaccharide export
KQ254_RS02395	COG0728	peptidoglycan biosynthetic process
KQ254_RS02400	COG3023	N-Acetylmuramoyl-L-alanine amidase
KQ254_RS02455	COG0546	phosphoglycolate phosphatase activity
KQ254_RS02460	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS02480	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ254_RS02485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ254_RS02490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ254_RS02495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ254_RS02500	COG1116	anion transmembrane transporter activity
KQ254_RS02505	COG1309	transcriptional regulator
KQ254_RS02510	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KQ254_RS02520	COG0196	riboflavin kinase activity
KQ254_RS02525	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KQ254_RS02535	COG1047	Peptidyl-prolyl cis-trans
KQ254_RS02575	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KQ254_RS02580	COG0657	acetylesterase activity
KQ254_RS02600	COG0583	DNA-binding transcription factor activity
KQ254_RS02630	COG2951	lytic endotransglycosylase activity
KQ254_RS02635	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KQ254_RS02650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KQ254_RS02660	COG3328	transposase activity
KQ254_RS02670	COG0671	phosphoesterase, PA-phosphatase related
KQ254_RS02675	COG0861	Integral membrane protein TerC family
KQ254_RS02685	COG0754	glutathionylspermidine amidase activity
KQ254_RS02695	COG0402	S-adenosylhomocysteine deaminase activity
KQ254_RS02710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ254_RS02715	COG1230	cation diffusion facilitator family transporter
KQ254_RS02730	COG0706	membrane insertase activity
KQ254_RS02755	COG0592	DNA-directed DNA polymerase activity
KQ254_RS02765	COG0187	DNA topoisomerase II activity
KQ254_RS02785	COG0586	Pfam SNARE associated Golgi protein
KQ254_RS02790	COG0488	(ABC) transporter
KQ254_RS02815	COG0596	Alpha beta hydrolase
KQ254_RS02820	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KQ254_RS02825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KQ254_RS02865	COG0733	neurotransmitter:sodium symporter activity
KQ254_RS02900	COG0583	DNA-binding transcription factor activity
KQ254_RS02905	COG2233	PERMEase
KQ254_RS02920	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_RS02955	COG2814	Major facilitator Superfamily
KQ254_RS02960	COG0656	L-ascorbic acid biosynthetic process
KQ254_RS02965	COG0583	DNA-binding transcription factor activity
KQ254_RS02980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ254_RS02985	COG1064	alcohol dehydrogenase
KQ254_RS02990	COG2818	Glycosylase
KQ254_RS03005	COG1194	a g-specific adenine glycosylase
KQ254_RS03025	COG2983	Belongs to the UPF0260 family
KQ254_RS03030	COG2133	pyrroloquinoline quinone binding
KQ254_RS03035	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KQ254_RS03040	COG2116	formate transmembrane transporter activity
KQ254_RS03060	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ254_RS03065	COG1335	isochorismatase
KQ254_RS03070	COG0385	Bile acid
KQ254_RS03075	COG0534	Mate efflux family protein
KQ254_RS03080	COG1683	Conserved Protein
KQ254_RS03100	COG0625	glutathione transferase activity
KQ254_RS03110	COG1113	amino acid transport
KQ254_RS03120	COG0523	cobalamin synthesis protein
KQ254_RS03130	COG2188	Transcriptional regulator
KQ254_RS03160	COG0010	Belongs to the arginase family
KQ254_RS03175	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ254_RS03265	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQ254_RS03275	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KQ254_RS03280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KQ254_RS03365	COG0534	Mate efflux family protein
KQ254_RS03370	COG0436	Aminotransferase
KQ254_RS03375	COG2733	membrane
KQ254_RS03390	COG2918	glutathione biosynthetic process
KQ254_RS03425	COG3150	esterase
KQ254_RS03435	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS03440	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KQ254_RS03450	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_RS03460	COG2233	PERMEase
KQ254_RS03465	COG2351	hydroxyisourate hydrolase activity
KQ254_RS03500	COG3706	GGDEF domain
KQ254_RS03515	COG1393	Belongs to the ArsC family
KQ254_RS03520	COG0708	Exodeoxyribonuclease III
KQ254_RS03540	COG0189	ligase activity
KQ254_RS03560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KQ254_RS03570	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KQ254_RS03585	COG4942	peptidase
KQ254_RS03595	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ254_RS03605	COG2119	membrane
KQ254_RS03610	COG4774	siderophore transport
KQ254_RS03615	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_RS03615	COG0426	domain, Protein
KQ254_RS03640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KQ254_RS03660	COG1902	pentaerythritol trinitrate reductase activity
KQ254_RS03665	COG1519	Transferase
KQ254_RS03670	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ254_RS03675	COG0668	transmembrane transport
KQ254_RS03685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ254_RS03690	COG1335	isochorismatase
KQ254_RS03695	COG1522	sequence-specific DNA binding
KQ254_RS03720	COG0784	Response regulator, receiver
KQ254_RS03720	COG2205	protein histidine kinase activity
KQ254_RS03720	COG2198	Histidine kinase
KQ254_RS03725	COG3162	membrane
KQ254_RS03730	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQ254_RS03740	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ254_RS03760	COG1309	transcriptional regulator
KQ254_RS03780	COG0352	thiamine-phosphate diphosphorylase activity
KQ254_RS03780	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KQ254_RS03780	COG0351	phosphomethylpyrimidine kinase
KQ254_RS03790	COG2814	Major facilitator Superfamily
KQ254_RS03805	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KQ254_RS03815	COG1113	amino acid transport
KQ254_RS03825	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ254_RS03830	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS03840	COG1335	isochorismatase
KQ254_RS03870	COG2814	Major facilitator Superfamily
KQ254_RS03875	COG0583	DNA-binding transcription factor activity
KQ254_RS03895	COG0667	Aldo Keto reductase
KQ254_RS03935	COG1733	regulation of RNA biosynthetic process
KQ254_RS03940	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_RS04010	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KQ254_RS04025	COG2329	Antibiotic biosynthesis monooxygenase
KQ254_RS04060	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KQ254_RS04090	COG0427	acetyl-CoA hydrolase
KQ254_RS04115	COG0659	secondary active sulfate transmembrane transporter activity
KQ254_RS04120	COG4221	oxidoreductase activity
KQ254_RS04125	COG2873	o-acetylhomoserine
KQ254_RS04130	COG0488	(ABC) transporter
KQ254_RS04195	COG0833	amino acid
KQ254_RS04240	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KQ254_RS04245	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KQ254_RS04260	COG2226	methyltransferase
KQ254_RS04310	COG0067	glutamate synthase
KQ254_RS04310	COG0069	glutamate synthase activity
KQ254_RS04310	COG0070	glutamate synthase
KQ254_RS04315	COG0493	'glutamate synthase
KQ254_RS04325	COG1704	LemA family
KQ254_RS04330	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KQ254_RS04350	COG3307	-O-antigen
KQ254_RS04370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQ254_RS04385	COG0194	GDP metabolic process
KQ254_RS04400	COG4969	Belongs to the N-Me-Phe pilin family
KQ254_RS04440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KQ254_RS04460	COG5380	lipid catabolic process
KQ254_RS04465	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KQ254_RS04490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KQ254_RS04495	COG0277	FAD linked oxidase domain protein
KQ254_RS04505	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KQ254_RS04510	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_RS04525	COG1289	transmembrane transporter activity
KQ254_RS04535	COG0628	permease
KQ254_RS04570	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS04595	COG3621	Patatin-like phospholipase
KQ254_RS04640	COG2226	methyltransferase
KQ254_RS04650	COG0833	amino acid
KQ254_RS04655	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ254_RS04660	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ254_RS04670	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS04710	COG0583	DNA-binding transcription factor activity
KQ254_RS04760	COG0517	IMP dehydrogenase activity
KQ254_RS04765	COG1983	PspC domain protein
KQ254_RS04775	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS04790	COG0408	coproporphyrinogen oxidase activity
KQ254_RS04810	COG0513	Belongs to the DEAD box helicase family
KQ254_RS04820	COG1127	ABC transporter
KQ254_RS04825	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KQ254_RS04835	COG2854	intermembrane phospholipid transfer
KQ254_RS04845	COG0598	Magnesium transport protein CorA
KQ254_RS04855	COG0494	nUDIX hydrolase
KQ254_RS04860	COG1040	competence protein
KQ254_RS04865	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KQ254_RS04885	COG1946	Acyl-CoA thioesterase
KQ254_RS04890	COG1301	dicarboxylic acid transport
KQ254_RS04905	COG1959	2 iron, 2 sulfur cluster binding
KQ254_RS04910	COG1017	nitric oxide dioxygenase activity
KQ254_RS04910	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_RS04920	COG0433	COG0433 Predicted ATPase
KQ254_RS04925	COG0626	cystathionine gamma-synthase activity
KQ254_RS05080	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS05085	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KQ254_RS05115	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KQ254_RS05135	COG0557	exoribonuclease II activity
KQ254_RS05180	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQ254_RS05185	COG2169	Transcriptional regulator
KQ254_RS05195	COG1295	ribonuclease BN
KQ254_RS05230	COG1702	phosphate starvation-inducible protein PhoH
KQ254_RS05240	COG1196	nuclear chromosome segregation
KQ254_RS05240	COG0741	lytic transglycosylase activity
KQ254_RS05240	COG0739	heme binding
KQ254_RS05270	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KQ254_RS05275	COG1183	phosphatidylcholine synthase activity
KQ254_RS05320	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS05325	COG1309	transcriptional regulator
KQ254_RS05340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ254_RS05345	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS05365	COG2969	positive regulation of protein catabolic process
KQ254_RS05375	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KQ254_RS05390	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KQ254_RS05395	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KQ254_RS05415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KQ254_RS05425	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ254_RS05430	COG1408	metallophosphoesterase
KQ254_RS05440	COG2199	diguanylate cyclase activity
KQ254_RS05500	COG1607	acyl-coa hydrolase
KQ254_RS05530	COG2350	Protein conserved in bacteria
KQ254_RS05540	COG0613	PHP domain protein
KQ254_RS05545	COG3781	membrane
KQ254_RS05555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KQ254_RS05560	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KQ254_RS05570	COG1862	Preprotein translocase
KQ254_RS05600	COG0582	viral genome integration into host DNA
KQ254_RS05620	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS05630	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KQ254_RS05650	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KQ254_RS05660	COG2205	protein histidine kinase activity
KQ254_RS05665	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KQ254_RS05685	COG0726	polysaccharide deacetylase
KQ254_RS05690	COG0463	Glycosyl transferase, family 2
KQ254_RS05695	COG0438	transferase activity, transferring glycosyl groups
KQ254_RS05760	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS05765	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS05775	COG2205	protein histidine kinase activity
KQ254_RS05780	COG0745	RESPONSE REGULATOR receiver
KQ254_RS05785	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KQ254_RS05800	COG0584	glycerophosphoryl diester phosphodiesterase
KQ254_RS05805	COG2096	Adenosyltransferase
KQ254_RS05810	COG4206	TonB-dependent receptor
KQ254_RS05855	COG0285	dihydrofolate synthase activity
KQ254_RS05875	COG0450	alkyl hydroperoxide reductase
KQ254_RS05895	COG0477	Major facilitator Superfamily
KQ254_RS05900	COG1272	protein, Hemolysin III
KQ254_RS05935	COG0183	Belongs to the thiolase family
KQ254_RS05940	COG2207	Transcriptional regulator
KQ254_RS05960	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ254_RS05980	COG0183	Belongs to the thiolase family
KQ254_RS05990	COG2885	chlorophyll binding
KQ254_RS05990	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KQ254_RS06095	COG0833	amino acid
KQ254_RS06105	COG2233	PERMEase
KQ254_RS06110	COG1217	gtp-binding protein TYPA
KQ254_RS06135	COG2094	Belongs to the DNA glycosylase MPG family
KQ254_RS06140	COG4772	TonB-dependent receptor
KQ254_RS06145	COG1902	pentaerythritol trinitrate reductase activity
KQ254_RS06160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ254_RS06165	COG0354	folic acid binding
KQ254_RS06180	COG3189	MarR family transcriptional regulator
KQ254_RS06185	COG2824	Alkylphosphonate utilization operon protein PhnA
KQ254_RS06190	COG3422	double-strand break repair
KQ254_RS06230	COG0840	transmembrane signaling receptor activity
KQ254_RS06250	COG5510	response to toxic substance
KQ254_RS06260	COG2832	Protein of unknown function (DUF454)
KQ254_RS06265	COG1376	ErfK ybiS ycfS ynhG family protein
KQ254_RS06305	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KQ254_RS06315	COG1289	transmembrane transporter activity
KQ254_RS06320	COG2814	Major facilitator Superfamily
KQ254_RS06340	COG1115	amino acid carrier protein
KQ254_RS06345	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ254_RS06350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQ254_RS06355	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KQ254_RS06360	COG3590	peptidase
KQ254_RS06385	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS06400	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ254_RS06410	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ254_RS06415	COG1077	Cell shape determining protein MreB Mrl
KQ254_RS06420	COG1792	Involved in formation and maintenance of cell shape
KQ254_RS06425	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KQ254_RS06430	COG0424	maF-like protein
KQ254_RS06435	COG1530	ribonuclease E activity
KQ254_RS06445	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ254_RS06455	COG0560	Phosphoserine phosphatase
KQ254_RS06465	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_RS06490	COG2207	Transcriptional regulator
KQ254_RS06540	COG1113	amino acid transport
KQ254_RS06545	COG2828	Protein conserved in bacteria
KQ254_RS06550	COG0142	geranyltranstransferase activity
KQ254_RS06555	COG2315	Protein conserved in bacteria
KQ254_RS06570	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ254_RS06590	COG2194	sulfuric ester hydrolase activity
KQ254_RS06595	COG0745	RESPONSE REGULATOR receiver
KQ254_RS06600	COG0642	Histidine kinase
KQ254_RS06610	COG0004	ammonium transporteR
KQ254_RS06615	COG0583	DNA-binding transcription factor activity
KQ254_RS06635	COG0525	valine-tRNA ligase activity
KQ254_RS06645	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS06655	COG0393	Putative heavy-metal-binding
KQ254_RS06660	COG0393	Putative heavy-metal-binding
KQ254_RS06665	COG1538	Outer membrane efflux protein
KQ254_RS06675	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_RS06680	COG0671	phosphoesterase, PA-phosphatase related
KQ254_RS06710	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KQ254_RS06725	COG1648	precorrin-2 dehydrogenase activity
KQ254_RS06725	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KQ254_RS06730	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KQ254_RS06735	COG1733	regulation of RNA biosynthetic process
KQ254_RS06745	COG0531	amino acid
KQ254_RS06760	COG0321	lipoyl(octanoyl) transferase activity
KQ254_RS06765	COG2921	Belongs to the UPF0250 family
KQ254_RS06800	COG2009	succinate dehydrogenase
KQ254_RS06805	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KQ254_RS06810	COG1053	succinate dehydrogenase
KQ254_RS06815	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KQ254_RS06840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ254_RS06860	COG2354	Protein conserved in bacteria
KQ254_RS06865	COG2321	neutral zinc metallopeptidase
KQ254_RS06885	COG2843	Capsule synthesis protein
KQ254_RS06900	COG0589	response to stress
KQ254_RS06910	COG0251	oxidation-reduction process
KQ254_RS06930	COG0505	Belongs to the CarA family
KQ254_RS06955	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ254_RS06960	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KQ254_RS07010	COG0477	Major facilitator Superfamily
KQ254_RS07015	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KQ254_RS07030	COG1597	lipid kinase activity
KQ254_RS07035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KQ254_RS07055	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ254_RS07060	COG0584	glycerophosphoryl diester phosphodiesterase
KQ254_RS07080	COG0741	lytic transglycosylase activity
KQ254_RS07100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KQ254_RS07115	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ254_RS07140	COG3811	Belongs to the UPF0386 family
KQ254_RS07160	COG0778	Nitroreductase
KQ254_RS07175	COG1929	Belongs to the glycerate kinase type-1 family
KQ254_RS07180	COG0243	molybdopterin cofactor binding
KQ254_RS07185	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KQ254_RS07190	COG3339	Conserved Protein
KQ254_RS07200	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KQ254_RS07215	COG1113	amino acid transport
KQ254_RS07225	COG0019	diaminopimelate decarboxylase activity
KQ254_RS07235	COG1280	lysine exporter protein (LysE YggA)
KQ254_RS07240	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KQ254_RS07270	COG0463	Glycosyl transferase, family 2
KQ254_RS07290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_RS07320	COG4591	ABC-type transport system involved in lipoprotein release permease component
KQ254_RS07325	COG1136	(ABC) transporter
KQ254_RS07330	COG0658	competence protein
KQ254_RS07330	COG2333	competence protein COMEC
KQ254_RS07340	COG0616	signal peptide processing
KQ254_RS07340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KQ254_RS07345	COG0596	Alpha beta hydrolase
KQ254_RS07350	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KQ254_RS07360	COG0628	permease
KQ254_RS07380	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS07405	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ254_RS07425	COG0823	Involved in the tonB-independent uptake of proteins
KQ254_RS07445	COG0824	Thioesterase
KQ254_RS07450	COG1473	amidohydrolase
KQ254_RS07470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KQ254_RS07470	COG0047	phosphoribosylformylglycinamidine synthase activity
KQ254_RS07475	COG2814	Major facilitator Superfamily
KQ254_RS07490	COG1024	Enoyl-CoA hydratase
KQ254_RS07495	COG1051	belongs to the nudix hydrolase family
KQ254_RS07495	COG1056	cytidyltransferase-related domain
KQ254_RS07505	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KQ254_RS07520	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KQ254_RS07535	COG4625	pathogenesis
KQ254_RS07540	COG0583	DNA-binding transcription factor activity
KQ254_RS07545	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KQ254_RS07550	COG4208	sulfate ABC transporter
KQ254_RS07555	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KQ254_RS07565	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KQ254_RS07570	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KQ254_RS07575	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KQ254_RS07595	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ254_RS07610	COG0681	Belongs to the peptidase S26 family
KQ254_RS07625	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KQ254_RS07635	COG1381	Involved in DNA repair and RecF pathway recombination
KQ254_RS07640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KQ254_RS07650	COG4221	oxidoreductase activity
KQ254_RS07680	COG0436	Aminotransferase
KQ254_RS07700	COG0556	nucleotide-excision repair
KQ254_RS07755	COG2070	2-Nitropropane dioxygenase
KQ254_RS07785	COG1215	transferase activity, transferring glycosyl groups
KQ254_RS07800	COG0415	Belongs to the DNA photolyase family
KQ254_RS07810	COG1252	NADH dehydrogenase
KQ254_RS07830	COG1187	pseudouridine synthase activity
KQ254_RS07855	COG0477	Major facilitator Superfamily
KQ254_RS07860	COG0583	DNA-binding transcription factor activity
KQ254_RS07865	COG1823	symporter activity
KQ254_RS07875	COG0612	Peptidase, M16
KQ254_RS07900	COG0352	thiamine-phosphate diphosphorylase activity
KQ254_RS07935	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_RS07945	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_RS07960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ254_RS07965	COG0076	glutamate decarboxylase activity
KQ254_RS07975	COG1522	sequence-specific DNA binding
KQ254_RS07980	COG3961	Belongs to the TPP enzyme family
KQ254_RS07985	COG1113	amino acid transport
KQ254_RS07990	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KQ254_RS07995	COG0573	inorganic phosphate transmembrane transporter activity
KQ254_RS08005	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQ254_RS08010	COG0616	signal peptide processing
KQ254_RS08045	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KQ254_RS08050	COG1686	Belongs to the peptidase S11 family
KQ254_RS08075	COG0583	DNA-binding transcription factor activity
KQ254_RS08080	COG1067	ATP-dependent peptidase activity
KQ254_RS08105	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KQ254_RS08125	COG1966	Carbon starvation protein
KQ254_RS08130	COG2879	small protein
KQ254_RS08140	COG0582	viral genome integration into host DNA
KQ254_RS08230	COG1741	Belongs to the pirin family
KQ254_RS08240	COG2964	Protein conserved in bacteria
KQ254_RS08255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ254_RS08260	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ254_RS08265	COG4605	iron ion homeostasis
KQ254_RS08270	COG4604	ABC transporter, ATP-binding protein
KQ254_RS08275	COG4607	ABC-type enterochelin transport system periplasmic component
KQ254_RS08280	COG4774	siderophore transport
KQ254_RS08290	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ254_RS08300	COG1535	isochorismatase
KQ254_RS08300	COG3433	isochorismatase activity
KQ254_RS08315	COG1132	(ABC) transporter
KQ254_RS08320	COG1132	(ABC) transporter
KQ254_RS08325	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KQ254_RS08330	COG2977	Belongs to the P-Pant transferase superfamily
KQ254_RS08350	COG3739	integral membrane protein
KQ254_RS08385	COG0302	gtp cyclohydrolase
KQ254_RS08395	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KQ254_RS08425	COG0308	aminopeptidase N
KQ254_RS08430	COG0512	Glutamine amidotransferase of anthranilate synthase
KQ254_RS08445	COG1876	peptidase activity
KQ254_RS08465	COG0174	glutamine synthetase
KQ254_RS08475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KQ254_RS08510	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KQ254_RS08515	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KQ254_RS08520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ254_RS08540	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ254_RS08545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KQ254_RS08550	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KQ254_RS08565	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS08570	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQ254_RS08575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ254_RS08585	COG2223	nitrite transmembrane transporter activity
KQ254_RS08595	COG0024	Methionine aminopeptidase
KQ254_RS08600	COG0052	Belongs to the universal ribosomal protein uS2 family
KQ254_RS08615	COG2207	Transcriptional regulator
KQ254_RS08640	COG2951	lytic endotransglycosylase activity
KQ254_RS08645	COG0772	Belongs to the SEDS family
KQ254_RS08660	COG0842	Transport permease protein
KQ254_RS08665	COG1131	(ABC) transporter
KQ254_RS08670	COG0582	viral genome integration into host DNA
KQ254_RS08985	COG3561	AntA/AntB antirepressor
KQ254_RS09075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_RS09090	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ254_RS09095	COG0826	peptidase U32
KQ254_RS09100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ254_RS09115	COG1720	tRNA m6t6A37 methyltransferase activity
KQ254_RS09125	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KQ254_RS09140	COG0642	Histidine kinase
KQ254_RS09150	COG0494	nUDIX hydrolase
KQ254_RS09160	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQ254_RS09165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KQ254_RS09170	COG3139	Protein of unknown function (DUF1315)
KQ254_RS09180	COG1301	dicarboxylic acid transport
KQ254_RS09185	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS09200	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KQ254_RS09210	COG2195	Cleaves the N-terminal amino acid of tripeptides
KQ254_RS09215	COG1234	tRNA 3'-trailer cleavage
KQ254_RS09245	COG2363	Small membrane protein
KQ254_RS09270	COG0513	Belongs to the DEAD box helicase family
KQ254_RS09280	COG0778	Nitroreductase
KQ254_RS09310	COG1286	toxin biosynthetic process
KQ254_RS09335	COG4783	chaperone-mediated protein folding
KQ254_RS09340	COG1610	YqeY-like protein
KQ254_RS09370	COG0515	serine threonine protein kinase
KQ254_RS09370	COG2815	serine threonine protein kinase
KQ254_RS09440	COG3111	PFAM Bacterial OB fold (BOF) protein
KQ254_RS09465	COG3243	poly(R)-hydroxyalkanoic acid synthase
KQ254_RS09470	COG0786	glutamate:sodium symporter activity
KQ254_RS09480	COG2186	Transcriptional regulator
KQ254_RS09495	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS09540	COG0477	Major facilitator Superfamily
KQ254_RS09565	COG2995	paraquat-inducible protein a
KQ254_RS09570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KQ254_RS09570	COG3008	intermembrane lipid transfer
KQ254_RS09585	COG3118	belongs to the thioredoxin family
KQ254_RS09585	COG0492	ferredoxin-NADP+ reductase activity
KQ254_RS09590	COG1794	racemase activity, acting on amino acids and derivatives
KQ254_RS09620	COG3739	integral membrane protein
KQ254_RS09665	COG1301	dicarboxylic acid transport
KQ254_RS09675	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ254_RS09680	COG2011	ABC-type metal ion transport system permease component
KQ254_RS09685	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ254_RS09690	COG1464	Belongs to the NlpA lipoprotein family
KQ254_RS09695	COG0151	Belongs to the GarS family
KQ254_RS09700	COG0138	bifunctional purine biosynthesis protein purh
KQ254_RS09705	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KQ254_RS09735	COG2308	Evidence 4 Homologs of previously reported genes of
KQ254_RS09745	COG1305	Transglutaminase-like
KQ254_RS09755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KQ254_RS09760	COG0305	Participates in initiation and elongation during chromosome replication
KQ254_RS09785	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KQ254_RS09795	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
KQ254_RS09800	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KQ254_RS09825	COG1649	PFAM Uncharacterised BCR, COG1649
KQ254_RS09825	COG0726	polysaccharide deacetylase
KQ254_RS09830	COG1215	transferase activity, transferring glycosyl groups
KQ254_RS09835	COG3658	cytochrome
KQ254_RS09845	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ254_RS09865	COG0583	DNA-binding transcription factor activity
KQ254_RS09885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ254_RS09890	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ254_RS09905	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS09910	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ254_RS09915	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_RS09940	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KQ254_RS09945	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KQ254_RS09955	COG2205	protein histidine kinase activity
KQ254_RS09960	COG0745	RESPONSE REGULATOR receiver
KQ254_RS09965	COG0174	glutamine synthetase
KQ254_RS09985	COG0729	surface antigen
KQ254_RS10020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ254_RS10025	COG2814	Major facilitator Superfamily
KQ254_RS10040	COG0583	DNA-binding transcription factor activity
KQ254_RS10055	COG1187	pseudouridine synthase activity
KQ254_RS10075	COG0802	atpase or kinase
KQ254_RS10080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KQ254_RS10090	COG1923	regulation of RNA biosynthetic process
KQ254_RS10095	COG0697	spore germination
KQ254_RS10115	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ254_RS10125	COG0519	Catalyzes the synthesis of GMP from XMP
KQ254_RS10125	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ254_RS10130	COG4302	ethanolamine ammonia-lyase activity
KQ254_RS10135	COG4303	Ethanolamine ammonia lyase large subunit
KQ254_RS10140	COG0531	amino acid
KQ254_RS10160	COG1454	alcohol dehydrogenase
KQ254_RS10165	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQ254_RS10175	COG2207	Transcriptional regulator
KQ254_RS10175	COG3708	Transcriptional regulator
KQ254_RS10195	COG0308	aminopeptidase N
KQ254_RS10240	COG1605	Chorismate mutase
KQ254_RS10255	COG1309	transcriptional regulator
KQ254_RS10265	COG0668	transmembrane transport
KQ254_RS10295	COG4773	Receptor
KQ254_RS10315	COG0488	(ABC) transporter
KQ254_RS10320	COG0589	response to stress
KQ254_RS10345	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KQ254_RS10355	COG3135	benzoate transporter
KQ254_RS10360	COG1522	sequence-specific DNA binding
KQ254_RS10370	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KQ254_RS10375	COG0583	DNA-binding transcription factor activity
KQ254_RS10385	COG0183	Belongs to the thiolase family
KQ254_RS10395	COG2030	dehydratase
KQ254_RS10400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ254_RS10415	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KQ254_RS10425	COG0824	Thioesterase
KQ254_RS10430	COG1454	alcohol dehydrogenase
KQ254_RS10440	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KQ254_RS10460	COG0069	glutamate synthase activity
KQ254_RS10480	COG2814	Major facilitator Superfamily
KQ254_RS10495	COG0511	ligase activity, forming carbon-carbon bonds
KQ254_RS10515	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ254_RS10515	COG1116	anion transmembrane transporter activity
KQ254_RS10520	COG0745	RESPONSE REGULATOR receiver
KQ254_RS10530	COG2146	nitrite reductase [NAD(P)H] activity
KQ254_RS10530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ254_RS10535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ254_RS10540	COG0243	molybdopterin cofactor binding
KQ254_RS10550	COG0243	molybdopterin cofactor binding
KQ254_RS10555	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KQ254_RS10570	COG0315	cyclic pyranopterin monophosphate synthase activity
KQ254_RS10570	COG0521	Mo-molybdopterin cofactor biosynthetic process
KQ254_RS10575	COG0303	'Molybdopterin
KQ254_RS10585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ254_RS10590	COG0697	spore germination
KQ254_RS10610	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KQ254_RS10615	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ254_RS10670	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS10680	COG2204	response regulator
KQ254_RS10685	COG3852	Histidine kinase
KQ254_RS10705	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KQ254_RS10710	COG0575	Belongs to the CDS family
KQ254_RS10725	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQ254_RS10745	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KQ254_RS10760	COG2137	regulation of response to DNA damage stimulus
KQ254_RS10770	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KQ254_RS10775	COG1011	Hydrolase
KQ254_RS10800	COG1522	sequence-specific DNA binding
KQ254_RS10810	COG1113	amino acid transport
KQ254_RS10835	COG0659	secondary active sulfate transmembrane transporter activity
KQ254_RS10840	COG2135	peptidase activity
KQ254_RS10855	COG3300	MHYT domain
KQ254_RS10855	COG5001	Diguanylate cyclase
KQ254_RS10875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ254_RS10875	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ254_RS10875	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KQ254_RS10880	COG1105	Belongs to the carbohydrate kinase PfkB family
KQ254_RS10885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KQ254_RS10885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ254_RS10915	COG0024	Methionine aminopeptidase
KQ254_RS10920	COG0583	DNA-binding transcription factor activity
KQ254_RS10930	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KQ254_RS10935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ254_RS10940	COG0516	GMP reductase activity
KQ254_RS10940	COG0517	IMP dehydrogenase activity
KQ254_RS10965	COG0552	protein localization to endoplasmic reticulum
KQ254_RS10975	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KQ254_RS10990	COG4890	Cyd operon protein YbgT
KQ254_RS10995	COG1294	oxidase, subunit
KQ254_RS11015	COG1585	Membrane protein implicated in regulation of membrane protease activity
KQ254_RS11025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQ254_RS11030	COG4774	siderophore transport
KQ254_RS11045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KQ254_RS11050	COG0569	domain protein
KQ254_RS11055	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQ254_RS11085	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KQ254_RS11090	COG0542	response to heat
KQ254_RS11115	COG1902	pentaerythritol trinitrate reductase activity
KQ254_RS11115	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ254_RS11160	COG2323	membrane
KQ254_RS11165	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KQ254_RS11175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ254_RS11180	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ254_RS11185	COG0183	Belongs to the thiolase family
KQ254_RS11190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KQ254_RS11195	COG0596	Alpha beta hydrolase
KQ254_RS11200	COG2271	Major facilitator Superfamily
KQ254_RS11205	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQ254_RS11210	COG3485	protocatechuate 3,4-dioxygenase
KQ254_RS11215	COG3485	protocatechuate 3,4-dioxygenase
KQ254_RS11220	COG0710	3-dehydroquinate dehydratase activity
KQ254_RS11225	COG3420	alginic acid biosynthetic process
KQ254_RS11235	COG4993	Dehydrogenase
KQ254_RS11245	COG2391	methyltransferase activity
KQ254_RS11260	COG1414	Transcriptional regulator
KQ254_RS11265	COG0583	DNA-binding transcription factor activity
KQ254_RS11270	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS11295	COG2814	Major facilitator Superfamily
KQ254_RS11305	COG0154	amidase activity
KQ254_RS11325	COG4638	Rieske (2fe-2S)
KQ254_RS11335	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS11345	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_RS11355	COG3733	amine oxidase
KQ254_RS11365	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS11370	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ254_RS11375	COG0183	Belongs to the thiolase family
KQ254_RS11380	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ254_RS11385	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ254_RS11395	COG4829	muconolactone delta-isomerase
KQ254_RS11400	COG4948	Mandelate Racemase Muconate Lactonizing
KQ254_RS11405	COG0583	DNA-binding transcription factor activity
KQ254_RS11415	COG2186	Transcriptional regulator
KQ254_RS11435	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS11450	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ254_RS11450	COG1902	pentaerythritol trinitrate reductase activity
KQ254_RS11465	COG0789	Transcriptional regulator
KQ254_RS11490	COG1309	transcriptional regulator
KQ254_RS11495	COG0583	DNA-binding transcription factor activity
KQ254_RS11500	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS11505	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS11510	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS11520	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS11530	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_RS11605	COG2188	Transcriptional regulator
KQ254_RS11620	COG0583	DNA-binding transcription factor activity
KQ254_RS11660	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS11665	COG0129	dihydroxy-acid dehydratase activity
KQ254_RS11675	COG0583	DNA-binding transcription factor activity
KQ254_RS11680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KQ254_RS11690	COG2084	Dehydrogenase
KQ254_RS11695	COG2207	Transcriptional regulator
KQ254_RS11710	COG1064	alcohol dehydrogenase
KQ254_RS11720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ254_RS11725	COG1120	ATPase activity
KQ254_RS11745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ254_RS11795	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KQ254_RS11865	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS11885	COG1073	alpha beta
KQ254_RS11895	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS11905	COG2207	Transcriptional regulator
KQ254_RS11915	COG2205	protein histidine kinase activity
KQ254_RS11920	COG0745	RESPONSE REGULATOR receiver
KQ254_RS11925	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ254_RS11930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KQ254_RS11945	COG3539	Fimbrial protein
KQ254_RS11970	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KQ254_RS11980	COG0753	catalase activity
KQ254_RS11995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ254_RS12055	COG3433	isochorismatase activity
KQ254_RS12055	COG1535	isochorismatase
KQ254_RS12060	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS12065	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KQ254_RS12070	COG4149	molybdate abc transporter
KQ254_RS12075	COG0725	ABC transporter, periplasmic molybdate-binding protein
KQ254_RS12085	COG4638	Rieske (2fe-2S)
KQ254_RS12090	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KQ254_RS12095	COG0543	2 iron, 2 sulfur cluster binding
KQ254_RS12095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_RS12110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_RS12120	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS12135	COG2207	Transcriptional regulator
KQ254_RS12140	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS12145	COG2610	gluconate transmembrane transporter activity
KQ254_RS12155	COG0583	DNA-binding transcription factor activity
KQ254_RS12170	COG2031	fatty acid transporter
KQ254_RS12175	COG0183	Belongs to the thiolase family
KQ254_RS12180	COG0583	DNA-binding transcription factor activity
KQ254_RS12185	COG0583	DNA-binding transcription factor activity
KQ254_RS12200	COG1027	Aspartate ammonia-lyase
KQ254_RS12210	COG0477	Major facilitator Superfamily
KQ254_RS12230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ254_RS12235	COG4521	taurine ABC transporter
KQ254_RS12245	COG2081	HI0933 family
KQ254_RS12250	COG2188	Transcriptional regulator
KQ254_RS12260	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KQ254_RS12265	COG1733	regulation of RNA biosynthetic process
KQ254_RS12270	COG3708	Transcriptional regulator
KQ254_RS12270	COG2207	Transcriptional regulator
KQ254_RS12285	COG0730	response to heat
KQ254_RS12300	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ254_RS12300	COG3453	Protein conserved in bacteria
KQ254_RS12310	COG3781	membrane
KQ254_RS12315	COG1063	alcohol dehydrogenase
KQ254_RS12325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ254_RS12330	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ254_RS12335	COG0022	dehydrogenase e1 component
KQ254_RS12340	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KQ254_RS12345	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQ254_RS12360	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS12370	COG3706	GGDEF domain
KQ254_RS12385	COG0133	tryptophan synthase activity
KQ254_RS12395	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ254_RS12430	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KQ254_RS12455	COG2226	methyltransferase
KQ254_RS12510	COG0842	Transport permease protein
KQ254_RS12515	COG0842	Transport permease protein
KQ254_RS12520	COG1131	(ABC) transporter
KQ254_RS12535	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KQ254_RS12540	COG4773	Receptor
KQ254_RS12560	COG0730	response to heat
KQ254_RS12565	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KQ254_RS12600	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQ254_RS12630	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ254_RS12640	COG4264	IucA IucC family
KQ254_RS12645	COG4264	IucA IucC family
KQ254_RS12665	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KQ254_RS12680	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS12685	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS12690	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KQ254_RS12695	COG2207	Transcriptional regulator
KQ254_RS12700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KQ254_RS12705	COG0776	regulation of translation
KQ254_RS12730	COG0822	iron-sulfur transferase activity
KQ254_RS12735	COG0316	Belongs to the HesB IscA family
KQ254_RS12765	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KQ254_RS12785	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ254_RS12790	COG0702	epimerase
KQ254_RS12825	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ254_RS12835	COG0339	signal peptide processing
KQ254_RS12855	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
KQ254_RS12880	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KQ254_RS12885	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KQ254_RS12915	COG0776	regulation of translation
KQ254_RS12980	COG0084	hydrolase, TatD family'
KQ254_RS13000	COG1663	tetraacyldisaccharide 4'-kinase activity
KQ254_RS13005	COG1132	(ABC) transporter
KQ254_RS13015	COG0811	peptide transport
KQ254_RS13020	COG1475	DNA binding
KQ254_RS13025	COG1192	Involved in chromosome partitioning
KQ254_RS13035	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KQ254_RS13050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KQ254_RS13055	COG0191	fructose-bisphosphate aldolase activity
KQ254_RS13075	COG0424	maF-like protein
KQ254_RS13080	COG2850	peptidyl-arginine hydroxylation
KQ254_RS13100	COG0640	Transcriptional regulator
KQ254_RS13110	COG3619	membrane
KQ254_RS13115	COG3122	Protein conserved in bacteria
KQ254_RS13120	COG1132	(ABC) transporter
KQ254_RS13140	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KQ254_RS13145	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQ254_RS13155	COG0506	proline dehydrogenase activity
KQ254_RS13155	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KQ254_RS13155	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KQ254_RS13160	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KQ254_RS13175	COG3698	Phosphodiester glycosidase
KQ254_RS13185	COG2353	YceI-like domain
KQ254_RS13195	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KQ254_RS13240	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KQ254_RS13240	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KQ254_RS13265	COG3539	Fimbrial protein
KQ254_RS13270	COG3121	Chaperone
KQ254_RS13295	COG0697	spore germination
KQ254_RS13305	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KQ254_RS13315	COG0583	DNA-binding transcription factor activity
KQ254_RS13360	COG1522	sequence-specific DNA binding
KQ254_RS13370	COG1126	abc transporter atp-binding protein
KQ254_RS13375	COG0765	amino acid transport
KQ254_RS13380	COG0765	amino acid transport
KQ254_RS13410	COG1464	Belongs to the NlpA lipoprotein family
KQ254_RS13420	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ254_RS13425	COG2011	ABC-type metal ion transport system permease component
KQ254_RS13430	COG0012	GTP binding
KQ254_RS13455	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KQ254_RS13495	COG0386	Belongs to the glutathione peroxidase family
KQ254_RS13505	COG0436	Aminotransferase
KQ254_RS13545	COG3634	alkyl hydroperoxide reductase activity
KQ254_RS13560	COG0583	DNA-binding transcription factor activity
KQ254_RS13565	COG0798	PFAM Bile acid sodium symporter
KQ254_RS13570	COG0640	Transcriptional regulator
KQ254_RS13585	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KQ254_RS13595	COG0583	DNA-binding transcription factor activity
KQ254_RS13605	COG1953	Uracil, thiamine, allantoin
KQ254_RS13615	COG2175	clavaminate synthase activity
KQ254_RS13620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ254_RS13625	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KQ254_RS13630	COG4521	taurine ABC transporter
KQ254_RS13640	COG0477	Major facilitator Superfamily
KQ254_RS13665	COG1271	oxidase subunit
KQ254_RS13670	COG1294	oxidase, subunit
KQ254_RS13680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ254_RS13700	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KQ254_RS13720	COG3052	prosthetic group binding
KQ254_RS13725	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KQ254_RS13735	COG0583	DNA-binding transcription factor activity
KQ254_RS13745	COG2814	Major facilitator Superfamily
KQ254_RS13765	COG1346	cytolysis
KQ254_RS13775	COG0583	DNA-binding transcription factor activity
KQ254_RS13780	COG0625	glutathione transferase activity
KQ254_RS13785	COG0625	glutathione transferase activity
KQ254_RS13790	COG0583	DNA-binding transcription factor activity
KQ254_RS13795	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS13805	COG1045	serine acetyltransferase
KQ254_RS13810	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ254_RS13815	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQ254_RS13825	COG1280	lysine exporter protein (LysE YggA)
KQ254_RS13840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ254_RS13845	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ254_RS13855	COG0765	amino acid transport
KQ254_RS13860	COG0765	amino acid transport
KQ254_RS13880	COG2205	protein histidine kinase activity
KQ254_RS13880	COG0784	Response regulator, receiver
KQ254_RS13900	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ254_RS13925	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS13975	COG0583	DNA-binding transcription factor activity
KQ254_RS13995	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_RS14000	COG1309	transcriptional regulator
KQ254_RS14005	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS14010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ254_RS14015	COG1024	Enoyl-CoA hydratase
KQ254_RS14020	COG4770	biotin carboxylase activity
KQ254_RS14030	COG0583	DNA-binding transcription factor activity
KQ254_RS14045	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS14055	COG2814	Major facilitator Superfamily
KQ254_RS14065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ254_RS14070	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ254_RS14075	COG2814	Major facilitator Superfamily
KQ254_RS14080	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS14085	COG1024	Enoyl-CoA hydratase
KQ254_RS14090	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS14095	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ254_RS14100	COG0183	Belongs to the thiolase family
KQ254_RS14110	COG2814	Major facilitator Superfamily
KQ254_RS14120	COG1024	Enoyl-CoA hydratase
KQ254_RS14135	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS14140	COG2814	Major facilitator Superfamily
KQ254_RS14145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQ254_RS14150	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KQ254_RS14165	COG3842	ATPase activity
KQ254_RS14170	COG1840	ABC-type Fe3 transport system, periplasmic component
KQ254_RS14180	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_RS14185	COG1414	Transcriptional regulator
KQ254_RS14195	COG0583	DNA-binding transcription factor activity
KQ254_RS14200	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQ254_RS14205	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS14215	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KQ254_RS14225	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS14230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ254_RS14235	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_RS14240	COG2267	carboxylic ester hydrolase activity
KQ254_RS14260	COG3038	cytochrome b561
KQ254_RS14265	COG0753	catalase activity
KQ254_RS14300	COG2050	protein possibly involved in aromatic compounds catabolism
KQ254_RS14310	COG3327	negative regulation of DNA-templated transcription, initiation
KQ254_RS14315	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KQ254_RS14320	COG0183	Belongs to the thiolase family
KQ254_RS14325	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ254_RS14330	COG1024	Enoyl-CoA hydratase
KQ254_RS14335	COG1024	Enoyl-CoA hydratase
KQ254_RS14340	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_RS14345	COG2151	metal-sulfur cluster biosynthetic enzyme
KQ254_RS14350	COG3396	Phenylacetate-CoA oxygenase
KQ254_RS14355	COG3460	Phenylacetate-CoA oxygenase
KQ254_RS14360	COG3396	Phenylacetate-CoA oxygenase
KQ254_RS14365	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS14365	COG2030	dehydratase
KQ254_RS14370	COG1760	l-serine dehydratase
KQ254_RS14375	COG0531	amino acid
KQ254_RS14380	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS14405	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ254_RS14425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ254_RS14435	COG0789	Transcriptional regulator
KQ254_RS14445	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KQ254_RS14460	COG2807	transmembrane transport
KQ254_RS14465	COG0590	tRNA wobble adenosine to inosine editing
KQ254_RS14595	COG1116	anion transmembrane transporter activity
KQ254_RS14610	COG0864	Transcriptional regulator
KQ254_RS14620	COG1733	regulation of RNA biosynthetic process
KQ254_RS14625	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ254_RS14630	COG0439	Biotin carboxylase
KQ254_RS14645	COG1063	alcohol dehydrogenase
KQ254_RS14655	COG1309	transcriptional regulator
KQ254_RS14670	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS14680	COG4770	biotin carboxylase activity
KQ254_RS14700	COG1914	H( )-stimulated, divalent metal cation uptake system
KQ254_RS14705	COG0583	DNA-binding transcription factor activity
KQ254_RS14745	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ254_RS14765	COG2814	Major facilitator Superfamily
KQ254_RS14780	COG1560	Kdo2-lipid A biosynthetic process
KQ254_RS14790	COG5006	permease, DMT superfamily
KQ254_RS14795	COG1522	sequence-specific DNA binding
KQ254_RS14810	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KQ254_RS14820	COG4122	O-methyltransferase activity
KQ254_RS14850	COG1538	Outer membrane efflux protein
KQ254_RS14855	COG1137	ATPase activity
KQ254_RS14860	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KQ254_RS14870	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KQ254_RS14875	COG0517	IMP dehydrogenase activity
KQ254_RS14875	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KQ254_RS14915	COG2814	Major facilitator Superfamily
KQ254_RS14950	COG1278	Cold shock
KQ254_RS14955	COG1280	lysine exporter protein (LysE YggA)
KQ254_RS14985	COG1570	exodeoxyribonuclease VII activity
KQ254_RS15035	COG0583	DNA-binding transcription factor activity
KQ254_RS15045	COG4638	Rieske (2fe-2S)
KQ254_RS15055	COG0633	Ferredoxin
KQ254_RS15055	COG0543	2 iron, 2 sulfur cluster binding
KQ254_RS15060	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS15065	COG3135	benzoate transporter
KQ254_RS15070	COG2814	Major facilitator Superfamily
KQ254_RS15085	COG1643	Atp-dependent helicase
KQ254_RS15090	COG0450	alkyl hydroperoxide reductase
KQ254_RS15100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KQ254_RS15110	COG3634	alkyl hydroperoxide reductase activity
KQ254_RS15130	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KQ254_RS15135	COG0625	glutathione transferase activity
KQ254_RS15150	COG2885	chlorophyll binding
KQ254_RS15185	COG0542	response to heat
KQ254_RS15200	COG1765	OsmC-like protein
KQ254_RS15215	COG0667	Aldo Keto reductase
KQ254_RS15230	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KQ254_RS15245	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KQ254_RS15255	COG0527	aspartate kinase activity
KQ254_RS15265	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KQ254_RS15275	COG3038	cytochrome b561
KQ254_RS15280	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KQ254_RS15285	COG2252	PERMEase
KQ254_RS15295	COG2072	flavoprotein involved in K transport
KQ254_RS15310	COG1741	Belongs to the pirin family
KQ254_RS15315	COG1309	transcriptional regulator
KQ254_RS15325	COG0300	oxidoreductase activity
KQ254_RS15330	COG2072	flavoprotein involved in K transport
KQ254_RS15335	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KQ254_RS15380	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ254_RS15395	COG2814	Major facilitator Superfamily
KQ254_RS15400	COG1024	Enoyl-CoA hydratase
KQ254_RS15405	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS15415	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS15435	COG1113	amino acid transport
KQ254_RS15485	COG1902	pentaerythritol trinitrate reductase activity
KQ254_RS15485	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ254_RS15495	COG4251	negative regulation of phosphorylation
KQ254_RS15495	COG3706	GGDEF domain
KQ254_RS15495	COG2203	Gaf domain
KQ254_RS15495	COG5001	Diguanylate cyclase
KQ254_RS15505	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ254_RS15525	COG4172	Belongs to the ABC transporter superfamily
KQ254_RS15530	COG4239	(ABC) transporter, permease
KQ254_RS15535	COG4174	ABC transporter (Permease)
KQ254_RS15545	COG1388	LysM domain
KQ254_RS15545	COG1388	LysM domain
KQ254_RS15545	COG0741	lytic transglycosylase activity
KQ254_RS15545	COG0741	lytic transglycosylase activity
KQ254_RS15550	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ254_RS15595	COG1279	arginine transmembrane transporter activity
KQ254_RS15615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_RS15620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ254_RS15625	COG0006	proline dipeptidase activity
KQ254_RS15710	COG1196	nuclear chromosome segregation
KQ254_RS15710	COG0741	lytic transglycosylase activity
KQ254_RS15710	COG0739	heme binding
KQ254_RS15780	COG0305	Participates in initiation and elongation during chromosome replication
KQ254_RS15795	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ254_RS15850	COG2194	sulfuric ester hydrolase activity
KQ254_RS15915	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS16195	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KQ254_RS16225	COG3384	dioxygenase
KQ254_RS16235	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ254_RS16240	COG2878	Part of a membrane complex involved in electron transport
KQ254_RS16245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KQ254_RS16270	COG0768	penicillin binding
KQ254_RS16275	COG0742	ribosomal rna small subunit methyltransferase
KQ254_RS16290	COG0830	nickel cation binding
KQ254_RS16300	COG0804	urea catabolic process
KQ254_RS16340	COG1253	flavin adenine dinucleotide binding
KQ254_RS16345	COG2851	Citrate transporter
KQ254_RS16395	COG1773	rubredoxin
KQ254_RS16400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ254_RS16410	COG0583	DNA-binding transcription factor activity
KQ254_RS16440	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KQ254_RS16445	COG4181	ATPase activity
KQ254_RS16490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KQ254_RS16510	COG0306	phosphate transporter
KQ254_RS16520	COG3958	Transketolase
KQ254_RS16525	COG3959	Transketolase, thiamine diphosphate binding domain
KQ254_RS16530	COG2271	Major facilitator Superfamily
KQ254_RS16535	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS16540	COG0583	DNA-binding transcription factor activity
KQ254_RS16560	COG2223	nitrite transmembrane transporter activity
KQ254_RS16565	COG2207	Transcriptional regulator
KQ254_RS16570	COG2066	Belongs to the glutaminase family
KQ254_RS16575	COG0242	peptide deformylase activity
KQ254_RS16580	COG0477	Major facilitator Superfamily
KQ254_RS16590	COG0028	Belongs to the TPP enzyme family
KQ254_RS16605	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS16610	COG2267	carboxylic ester hydrolase activity
KQ254_RS16620	COG2271	Major facilitator Superfamily
KQ254_RS16625	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ254_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
KQ254_RS16655	COG1414	Transcriptional regulator
KQ254_RS16670	COG1024	Enoyl-CoA hydratase
KQ254_RS16680	COG1215	transferase activity, transferring glycosyl groups
KQ254_RS16685	COG1649	PFAM Uncharacterised BCR, COG1649
KQ254_RS16685	COG0726	polysaccharide deacetylase
KQ254_RS16695	COG4681	YaeQ
KQ254_RS16705	COG0523	cobalamin synthesis protein
KQ254_RS16715	COG1607	acyl-coa hydrolase
KQ254_RS16725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ254_RS16730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ254_RS16735	COG1309	transcriptional regulator
KQ254_RS16760	COG2040	homocysteine
KQ254_RS16765	COG0531	amino acid
KQ254_RS16820	COG1595	DNA-templated transcription, initiation
KQ254_RS16830	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ254_RS16835	COG0477	Major facilitator Superfamily
KQ254_RS16860	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KQ254_RS16870	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KQ254_RS16890	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ254_RS16975	COG0592	DNA-directed DNA polymerase activity
KQ254_RS17015	COG2026	Addiction module toxin, RelE StbE family
KQ254_RS17210	COG1484	DNA-dependent DNA replication
KQ254_RS17305	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ254_RS17375	COG0405	Gamma-glutamyltransferase
KQ254_RS17380	COG2814	Major facilitator Superfamily
KQ254_RS17390	COG2050	protein possibly involved in aromatic compounds catabolism
KQ254_RS17405	COG1090	epimerase
KQ254_RS17425	COG0420	3'-5' exonuclease activity
KQ254_RS17450	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS17460	COG0735	belongs to the Fur family
KQ254_RS17465	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQ254_RS17485	COG0121	glutamine amidotransferase
KQ254_RS17500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ254_RS17510	COG0210	DNA helicase
KQ254_RS17515	COG2885	chlorophyll binding
KQ254_RS17520	COG0204	Acyl-transferase
KQ254_RS17535	COG2894	cell division
KQ254_RS17550	COG1280	lysine exporter protein (LysE YggA)
KQ254_RS17555	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KQ254_RS17555	COG1674	ftsk spoiiie
KQ254_RS17560	COG0492	ferredoxin-NADP+ reductase activity
KQ254_RS17565	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KQ254_RS17575	COG0456	acetyltransferase
KQ254_RS17620	COG1981	membrane
KQ254_RS17635	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ254_RS17635	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KQ254_RS17655	COG1012	belongs to the aldehyde dehydrogenase family
KQ254_RS17665	COG0657	acetylesterase activity
KQ254_RS17675	COG0473	3-isopropylmalate dehydrogenase activity
KQ254_RS17680	COG0583	DNA-binding transcription factor activity
KQ254_RS17700	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ254_RS17710	COG0582	viral genome integration into host DNA
KQ254_RS18030	COG0564	pseudouridine synthase activity
KQ254_RS18040	COG0358	DNA primase activity
KQ254_RS18060	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KQ254_RS18090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ254_RS18120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KQ254_RS18130	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KQ254_RS18130	COG0352	thiamine-phosphate diphosphorylase activity
KQ254_RS18130	COG0351	phosphomethylpyrimidine kinase
KQ254_RS18135	COG1652	LysM domain
KQ254_RS18160	COG1399	metal-binding, possibly nucleic acid-binding protein
KQ254_RS18165	COG3101	peptidyl-lysine hydroxylation
KQ254_RS18170	COG0009	L-threonylcarbamoyladenylate synthase
KQ254_RS18175	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KQ254_RS18180	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KQ254_RS18195	COG4106	trans-aconitate 2-methyltransferase activity
KQ254_RS18210	COG2226	methyltransferase
KQ254_RS18210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ254_RS18210	COG0596	Alpha beta hydrolase
KQ254_RS18215	COG1877	trehalose-phosphatase activity
KQ254_RS18220	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KQ254_RS18225	COG2223	nitrite transmembrane transporter activity
KQ254_RS18245	COG1196	nuclear chromosome segregation
KQ254_RS18255	COG0730	response to heat
KQ254_RS18270	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KQ254_RS18280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ254_RS18330	COG0489	protein tyrosine kinase activity
KQ254_RS18340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ254_RS18340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ254_RS18370	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KQ254_RS18375	COG2081	HI0933 family
KQ254_RS18385	COG0668	transmembrane transport
KQ254_RS18405	COG0583	DNA-binding transcription factor activity
KQ254_RS18425	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQ254_RS18430	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQ254_RS18460	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KQ254_RS18485	COG3706	GGDEF domain
KQ254_RS18500	COG0745	RESPONSE REGULATOR receiver
KQ254_RS18520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KQ254_RS18535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ254_RS18550	COG0583	DNA-binding transcription factor activity
KQ254_RS18560	COG0583	DNA-binding transcription factor activity
KQ254_RS18575	COG0583	DNA-binding transcription factor activity
KQ254_RS18580	COG1053	succinate dehydrogenase
KQ254_RS18595	COG1309	transcriptional regulator
KQ254_RS18600	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQ254_RS18605	COG2814	Major facilitator Superfamily
KQ254_RS18610	COG1960	acyl-CoA dehydrogenase activity
KQ254_RS18615	COG0583	DNA-binding transcription factor activity
KQ254_RS18650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KQ254_RS18655	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KQ254_RS18660	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ254_RS18675	COG3667	copper resistance
KQ254_RS18680	COG2132	Multicopper oxidase
KQ254_RS18690	COG0561	phosphatase activity
KQ254_RS18695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KQ254_RS18705	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
KQ254_RS18720	COG1214	PFAM Peptidase M22, glycoprotease
KQ254_RS18740	COG3328	transposase activity
KQ254_RS18755	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KQ254_RS18765	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KQ254_RS18770	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KQ254_RS18775	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KQ254_RS18835	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ254_RS18845	COG1846	Transcriptional regulator
KQ254_RS18850	COG1764	response to oxidative stress
KQ254_RS18890	COG0037	tRNA processing
KQ254_RS18900	COG0248	Ppx GppA phosphatase
KQ254_RS18930	COG0072	phenylalanine-tRNA ligase activity
KQ254_RS18975	COG1238	metal cluster binding
KQ254_RS18980	COG0625	glutathione transferase activity
KQ254_RS18995	COG0318	PFAM AMP-dependent synthetase and ligase
KQ254_RS19000	COG3028	Belongs to the UPF0307 family
KQ254_RS19005	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ254_RS19025	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KQ254_RS19030	COG0617	tRNA 3'-terminal CCA addition
KQ254_RS19035	COG1555	photosystem II stabilization
KQ254_RS19040	COG3956	TIGRFAM MazG family protein
KQ254_RS19050	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQ254_RS19070	COG2205	protein histidine kinase activity
KQ254_RS19070	COG5002	protein histidine kinase activity
KQ254_RS19070	COG0784	Response regulator, receiver
KQ254_RS19075	COG1024	Enoyl-CoA hydratase
KQ254_RS19080	COG2084	Dehydrogenase
KQ254_RS19085	COG3622	Belongs to the hyi family
KQ254_RS19115	COG0697	spore germination
KQ254_RS19125	COG2814	Major facilitator Superfamily
KQ254_RS19130	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ254_RS19140	COG0583	DNA-binding transcription factor activity
KQ254_RS19150	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KQ254_RS19160	COG0084	hydrolase, TatD family'
KQ254_RS19175	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KQ254_RS19195	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ254_RS19200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ254_RS19235	COG2184	nucleotidyltransferase activity
KQ254_RS19255	COG1785	Belongs to the alkaline phosphatase family
KQ254_RS19315	COG2948	multi-organism process
KQ254_RS19330	COG0582	viral genome integration into host DNA
KQ254_RS19360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ254_RS19420	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS19430	COG2826	transposase and inactivated derivatives, IS30 family
KQ254_RS19500	COG0582	viral genome integration into host DNA
KQ254_RS19675	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system