locus-tag	class	description
KQ257_RS00025	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
KQ257_RS00035	COG2353	YceI-like domain
KQ257_RS00045	COG3698	Phosphodiester glycosidase
KQ257_RS00060	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
KQ257_RS00065	COG0506	proline dehydrogenase activity
KQ257_RS00065	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KQ257_RS00065	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
KQ257_RS00075	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQ257_RS00080	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KQ257_RS00100	COG1132	(ABC) transporter
KQ257_RS00105	COG3122	Protein conserved in bacteria
KQ257_RS00110	COG3619	membrane
KQ257_RS00120	COG0640	Transcriptional regulator
KQ257_RS00130	COG2850	peptidyl-arginine hydroxylation
KQ257_RS00135	COG0424	maF-like protein
KQ257_RS00155	COG0191	fructose-bisphosphate aldolase activity
KQ257_RS00160	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KQ257_RS00175	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
KQ257_RS00185	COG1192	Involved in chromosome partitioning
KQ257_RS00190	COG1475	DNA binding
KQ257_RS00195	COG0811	peptide transport
KQ257_RS00205	COG1132	(ABC) transporter
KQ257_RS00210	COG1663	tetraacyldisaccharide 4'-kinase activity
KQ257_RS00230	COG0084	hydrolase, TatD family'
KQ257_RS00295	COG0776	regulation of translation
KQ257_RS00325	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
KQ257_RS00330	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
KQ257_RS00375	COG0339	signal peptide processing
KQ257_RS00385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KQ257_RS00420	COG0702	epimerase
KQ257_RS00425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ257_RS00445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
KQ257_RS00475	COG0316	Belongs to the HesB IscA family
KQ257_RS00480	COG0822	iron-sulfur transferase activity
KQ257_RS00505	COG0776	regulation of translation
KQ257_RS00510	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
KQ257_RS00515	COG2207	Transcriptional regulator
KQ257_RS00520	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KQ257_RS00525	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS00530	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS00545	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KQ257_RS00565	COG4264	IucA IucC family
KQ257_RS00570	COG4264	IucA IucC family
KQ257_RS00580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ257_RS00610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQ257_RS00625	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
KQ257_RS00645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KQ257_RS00650	COG0730	response to heat
KQ257_RS00670	COG4773	Receptor
KQ257_RS00675	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KQ257_RS00690	COG1131	(ABC) transporter
KQ257_RS00695	COG0842	Transport permease protein
KQ257_RS00700	COG0842	Transport permease protein
KQ257_RS00755	COG2226	methyltransferase
KQ257_RS00780	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
KQ257_RS00815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ257_RS00825	COG0133	tryptophan synthase activity
KQ257_RS00840	COG3706	GGDEF domain
KQ257_RS00855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQ257_RS00860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
KQ257_RS00865	COG0022	dehydrogenase e1 component
KQ257_RS00870	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ257_RS00875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ257_RS00885	COG1063	alcohol dehydrogenase
KQ257_RS00890	COG3781	membrane
KQ257_RS00900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ257_RS00900	COG3453	Protein conserved in bacteria
KQ257_RS00915	COG0730	response to heat
KQ257_RS00930	COG3708	Transcriptional regulator
KQ257_RS00930	COG2207	Transcriptional regulator
KQ257_RS00935	COG1733	regulation of RNA biosynthetic process
KQ257_RS00940	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
KQ257_RS00950	COG2188	Transcriptional regulator
KQ257_RS00965	COG4521	taurine ABC transporter
KQ257_RS00970	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ257_RS00990	COG0477	Major facilitator Superfamily
KQ257_RS01000	COG1027	Aspartate ammonia-lyase
KQ257_RS01015	COG0583	DNA-binding transcription factor activity
KQ257_RS01020	COG0583	DNA-binding transcription factor activity
KQ257_RS01025	COG0183	Belongs to the thiolase family
KQ257_RS01030	COG2031	fatty acid transporter
KQ257_RS01045	COG0583	DNA-binding transcription factor activity
KQ257_RS01065	COG1309	transcriptional regulator
KQ257_RS01075	COG2610	gluconate transmembrane transporter activity
KQ257_RS01080	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS01085	COG2207	Transcriptional regulator
KQ257_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS01110	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ257_RS01125	COG0543	2 iron, 2 sulfur cluster binding
KQ257_RS01125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ257_RS01130	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
KQ257_RS01135	COG4638	Rieske (2fe-2S)
KQ257_RS01145	COG0725	ABC transporter, periplasmic molybdate-binding protein
KQ257_RS01150	COG4149	molybdate abc transporter
KQ257_RS01155	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
KQ257_RS01160	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS01165	COG3433	isochorismatase activity
KQ257_RS01165	COG1535	isochorismatase
KQ257_RS01225	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ257_RS01240	COG0753	catalase activity
KQ257_RS01250	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
KQ257_RS01285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
KQ257_RS01290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ257_RS01295	COG0745	RESPONSE REGULATOR receiver
KQ257_RS01300	COG2205	protein histidine kinase activity
KQ257_RS01310	COG2207	Transcriptional regulator
KQ257_RS01325	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS01370	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
KQ257_RS01455	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ257_RS01475	COG1120	ATPase activity
KQ257_RS01480	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ257_RS01485	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
KQ257_RS01490	COG1064	alcohol dehydrogenase
KQ257_RS01495	COG2207	Transcriptional regulator
KQ257_RS01500	COG2084	Dehydrogenase
KQ257_RS01510	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KQ257_RS01515	COG0583	DNA-binding transcription factor activity
KQ257_RS01525	COG0129	dihydroxy-acid dehydratase activity
KQ257_RS01545	COG1566	PFAM secretion protein HlyD family protein
KQ257_RS01555	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
KQ257_RS01585	COG0583	DNA-binding transcription factor activity
KQ257_RS01600	COG2188	Transcriptional regulator
KQ257_RS01660	COG1473	amidohydrolase
KQ257_RS01670	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ257_RS01670	COG0475	glutathione-regulated potassium exporter activity
KQ257_RS01680	COG0583	DNA-binding transcription factor activity
KQ257_RS01685	COG1335	isochorismatase
KQ257_RS01695	COG1309	transcriptional regulator
KQ257_RS01720	COG0789	Transcriptional regulator
KQ257_RS01735	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ257_RS01735	COG1902	pentaerythritol trinitrate reductase activity
KQ257_RS01750	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS01770	COG2186	Transcriptional regulator
KQ257_RS01780	COG0583	DNA-binding transcription factor activity
KQ257_RS01785	COG4948	Mandelate Racemase Muconate Lactonizing
KQ257_RS01790	COG4829	muconolactone delta-isomerase
KQ257_RS01800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ257_RS01805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ257_RS01810	COG0183	Belongs to the thiolase family
KQ257_RS01815	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ257_RS01825	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS01835	COG3733	amine oxidase
KQ257_RS01845	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ257_RS01855	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS01865	COG4638	Rieske (2fe-2S)
KQ257_RS01885	COG0154	amidase activity
KQ257_RS01895	COG2814	Major facilitator Superfamily
KQ257_RS01920	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS01925	COG0583	DNA-binding transcription factor activity
KQ257_RS01930	COG1414	Transcriptional regulator
KQ257_RS01945	COG2391	methyltransferase activity
KQ257_RS01955	COG4993	Dehydrogenase
KQ257_RS01960	COG3659	wide pore channel activity
KQ257_RS01965	COG3420	alginic acid biosynthetic process
KQ257_RS01970	COG0710	3-dehydroquinate dehydratase activity
KQ257_RS01975	COG3485	protocatechuate 3,4-dioxygenase
KQ257_RS01980	COG3485	protocatechuate 3,4-dioxygenase
KQ257_RS01985	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQ257_RS01990	COG2271	Major facilitator Superfamily
KQ257_RS01995	COG0596	Alpha beta hydrolase
KQ257_RS02000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KQ257_RS02005	COG0183	Belongs to the thiolase family
KQ257_RS02010	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ257_RS02015	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ257_RS02025	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
KQ257_RS02030	COG2323	membrane
KQ257_RS02075	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ257_RS02075	COG1902	pentaerythritol trinitrate reductase activity
KQ257_RS02100	COG0542	response to heat
KQ257_RS02105	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
KQ257_RS02135	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQ257_RS02140	COG0569	domain protein
KQ257_RS02145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KQ257_RS02160	COG4774	siderophore transport
KQ257_RS02165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KQ257_RS02175	COG1585	Membrane protein implicated in regulation of membrane protease activity
KQ257_RS02190	COG1294	oxidase, subunit
KQ257_RS02195	COG4890	Cyd operon protein YbgT
KQ257_RS02210	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
KQ257_RS02220	COG0552	protein localization to endoplasmic reticulum
KQ257_RS02245	COG0516	GMP reductase activity
KQ257_RS02245	COG0517	IMP dehydrogenase activity
KQ257_RS02250	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ257_RS02255	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
KQ257_RS02265	COG0583	DNA-binding transcription factor activity
KQ257_RS02270	COG0024	Methionine aminopeptidase
KQ257_RS02300	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KQ257_RS02300	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ257_RS02305	COG1105	Belongs to the carbohydrate kinase PfkB family
KQ257_RS02310	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
KQ257_RS02310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ257_RS02310	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
KQ257_RS02325	COG5001	Diguanylate cyclase
KQ257_RS02325	COG3300	MHYT domain
KQ257_RS02345	COG3328	transposase activity
KQ257_RS02355	COG0659	secondary active sulfate transmembrane transporter activity
KQ257_RS02375	COG1113	amino acid transport
KQ257_RS02385	COG1522	sequence-specific DNA binding
KQ257_RS02410	COG1011	Hydrolase
KQ257_RS02415	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
KQ257_RS02425	COG2137	regulation of response to DNA damage stimulus
KQ257_RS02440	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
KQ257_RS02460	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQ257_RS02475	COG0575	Belongs to the CDS family
KQ257_RS02480	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
KQ257_RS02500	COG3852	Histidine kinase
KQ257_RS02505	COG2204	response regulator
KQ257_RS02560	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ257_RS02565	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
KQ257_RS02585	COG0697	spore germination
KQ257_RS02590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ257_RS02600	COG0303	'Molybdopterin
KQ257_RS02605	COG0315	cyclic pyranopterin monophosphate synthase activity
KQ257_RS02605	COG0521	Mo-molybdopterin cofactor biosynthetic process
KQ257_RS02620	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
KQ257_RS02625	COG0243	molybdopterin cofactor binding
KQ257_RS02635	COG0243	molybdopterin cofactor binding
KQ257_RS02640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ257_RS02645	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ257_RS02645	COG2146	nitrite reductase [NAD(P)H] activity
KQ257_RS02655	COG0745	RESPONSE REGULATOR receiver
KQ257_RS02660	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ257_RS02660	COG1116	anion transmembrane transporter activity
KQ257_RS02680	COG0511	ligase activity, forming carbon-carbon bonds
KQ257_RS02695	COG2814	Major facilitator Superfamily
KQ257_RS02715	COG1278	Cold shock
KQ257_RS02740	COG3179	chitinase
KQ257_RS02775	COG3293	Transposase
KQ257_RS02785	COG0739	heme binding
KQ257_RS02810	COG1598	PFAM Uncharacterised protein family UPF0150
KQ257_RS02915	COG3293	Transposase
KQ257_RS02970	COG3328	transposase activity
KQ257_RS03140	COG0069	glutamate synthase activity
KQ257_RS03160	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KQ257_RS03170	COG1454	alcohol dehydrogenase
KQ257_RS03175	COG0824	Thioesterase
KQ257_RS03190	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KQ257_RS03205	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ257_RS03210	COG2030	dehydratase
KQ257_RS03220	COG0183	Belongs to the thiolase family
KQ257_RS03230	COG0583	DNA-binding transcription factor activity
KQ257_RS03235	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KQ257_RS03245	COG1522	sequence-specific DNA binding
KQ257_RS03285	COG0589	response to stress
KQ257_RS03290	COG0488	(ABC) transporter
KQ257_RS03310	COG4773	Receptor
KQ257_RS03340	COG0668	transmembrane transport
KQ257_RS03350	COG1309	transcriptional regulator
KQ257_RS03365	COG1605	Chorismate mutase
KQ257_RS03405	COG0308	aminopeptidase N
KQ257_RS03425	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
KQ257_RS03435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQ257_RS03440	COG1454	alcohol dehydrogenase
KQ257_RS03460	COG0531	amino acid
KQ257_RS03465	COG4303	Ethanolamine ammonia lyase large subunit
KQ257_RS03470	COG4302	ethanolamine ammonia-lyase activity
KQ257_RS03475	COG0519	Catalyzes the synthesis of GMP from XMP
KQ257_RS03475	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ257_RS03480	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ257_RS03505	COG0697	spore germination
KQ257_RS03510	COG1923	regulation of RNA biosynthetic process
KQ257_RS03520	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
KQ257_RS03525	COG0802	atpase or kinase
KQ257_RS03545	COG1187	pseudouridine synthase activity
KQ257_RS03560	COG0583	DNA-binding transcription factor activity
KQ257_RS03580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ257_RS03605	COG0729	surface antigen
KQ257_RS03625	COG0174	glutamine synthetase
KQ257_RS03630	COG0745	RESPONSE REGULATOR receiver
KQ257_RS03635	COG2205	protein histidine kinase activity
KQ257_RS03645	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
KQ257_RS03650	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
KQ257_RS03675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ257_RS03680	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ257_RS03685	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS03700	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ257_RS03705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ257_RS03725	COG0583	DNA-binding transcription factor activity
KQ257_RS03740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ257_RS03750	COG3658	cytochrome
KQ257_RS03755	COG1215	transferase activity, transferring glycosyl groups
KQ257_RS03760	COG1649	PFAM Uncharacterised BCR, COG1649
KQ257_RS03760	COG0726	polysaccharide deacetylase
KQ257_RS03785	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
KQ257_RS03800	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
KQ257_RS03825	COG0305	Participates in initiation and elongation during chromosome replication
KQ257_RS03830	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KQ257_RS03840	COG1305	Transglutaminase-like
KQ257_RS03850	COG2308	Evidence 4 Homologs of previously reported genes of
KQ257_RS03880	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
KQ257_RS03885	COG0138	bifunctional purine biosynthesis protein purh
KQ257_RS03890	COG0151	Belongs to the GarS family
KQ257_RS03895	COG1464	Belongs to the NlpA lipoprotein family
KQ257_RS03900	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ257_RS03905	COG2011	ABC-type metal ion transport system permease component
KQ257_RS03910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ257_RS03920	COG1301	dicarboxylic acid transport
KQ257_RS03950	COG1794	racemase activity, acting on amino acids and derivatives
KQ257_RS03960	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
KQ257_RS03960	COG3008	intermembrane lipid transfer
KQ257_RS03965	COG2995	paraquat-inducible protein a
KQ257_RS03995	COG1051	belongs to the nudix hydrolase family
KQ257_RS04000	COG0477	Major facilitator Superfamily
KQ257_RS04050	COG2186	Transcriptional regulator
KQ257_RS04060	COG0786	glutamate:sodium symporter activity
KQ257_RS04065	COG3243	poly(R)-hydroxyalkanoic acid synthase
KQ257_RS04090	COG3111	PFAM Bacterial OB fold (BOF) protein
KQ257_RS04160	COG0515	serine threonine protein kinase
KQ257_RS04160	COG2815	serine threonine protein kinase
KQ257_RS04190	COG1610	YqeY-like protein
KQ257_RS04195	COG4783	chaperone-mediated protein folding
KQ257_RS04220	COG1286	toxin biosynthetic process
KQ257_RS04250	COG0778	Nitroreductase
KQ257_RS04260	COG0513	Belongs to the DEAD box helicase family
KQ257_RS04285	COG2363	Small membrane protein
KQ257_RS04315	COG1234	tRNA 3'-trailer cleavage
KQ257_RS04320	COG2195	Cleaves the N-terminal amino acid of tripeptides
KQ257_RS04330	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
KQ257_RS04340	COG2819	hydrolase of the alpha beta superfamily
KQ257_RS04345	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS04350	COG1301	dicarboxylic acid transport
KQ257_RS04355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KQ257_RS04360	COG3139	Protein of unknown function (DUF1315)
KQ257_RS04365	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
KQ257_RS04370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KQ257_RS04380	COG0494	nUDIX hydrolase
KQ257_RS04390	COG0642	Histidine kinase
KQ257_RS04405	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KQ257_RS04415	COG1720	tRNA m6t6A37 methyltransferase activity
KQ257_RS04430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ257_RS04435	COG0826	peptidase U32
KQ257_RS04440	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ257_RS04450	COG4598	ABC transporter
KQ257_RS04455	COG4160	amino acid transport
KQ257_RS04460	COG4215	(ABC) transporter
KQ257_RS04475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ257_RS04565	COG3561	AntA/AntB antirepressor
KQ257_RS04665	COG0653	protein targeting
KQ257_RS04675	COG3728	DNA packaging
KQ257_RS04860	COG0582	viral genome integration into host DNA
KQ257_RS04865	COG1131	(ABC) transporter
KQ257_RS04870	COG0842	Transport permease protein
KQ257_RS04885	COG0772	Belongs to the SEDS family
KQ257_RS04890	COG2951	lytic endotransglycosylase activity
KQ257_RS04915	COG2207	Transcriptional regulator
KQ257_RS04930	COG0052	Belongs to the universal ribosomal protein uS2 family
KQ257_RS04935	COG0024	Methionine aminopeptidase
KQ257_RS04945	COG2223	nitrite transmembrane transporter activity
KQ257_RS04955	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ257_RS04960	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
KQ257_RS04965	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS04980	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
KQ257_RS04985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KQ257_RS04990	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ257_RS05000	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS05020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ257_RS05025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KQ257_RS05030	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
KQ257_RS05065	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
KQ257_RS05075	COG0174	glutamine synthetase
KQ257_RS05090	COG0512	Glutamine amidotransferase of anthranilate synthase
KQ257_RS05095	COG0308	aminopeptidase N
KQ257_RS05125	COG1529	Aldehyde oxidase and xanthine dehydrogenase
KQ257_RS05135	COG0302	gtp cyclohydrolase
KQ257_RS05160	COG3739	integral membrane protein
KQ257_RS05175	COG1169	isochorismate synthase
KQ257_RS05185	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
KQ257_RS05190	COG1132	(ABC) transporter
KQ257_RS05195	COG1132	(ABC) transporter
KQ257_RS05210	COG1535	isochorismatase
KQ257_RS05210	COG3433	isochorismatase activity
KQ257_RS05215	COG1021	2,3-dihydroxybenzoate-AMP ligase
KQ257_RS05220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ257_RS05230	COG4774	siderophore transport
KQ257_RS05235	COG4607	ABC-type enterochelin transport system periplasmic component
KQ257_RS05240	COG4604	ABC transporter, ATP-binding protein
KQ257_RS05245	COG4605	iron ion homeostasis
KQ257_RS05250	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
KQ257_RS05255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ257_RS05270	COG2964	Protein conserved in bacteria
KQ257_RS05280	COG1741	Belongs to the pirin family
KQ257_RS05310	COG3328	transposase activity
KQ257_RS05330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
KQ257_RS05340	COG0596	Alpha beta hydrolase
KQ257_RS05355	COG0583	DNA-binding transcription factor activity
KQ257_RS05360	COG1335	isochorismatase
KQ257_RS05390	COG3328	transposase activity
KQ257_RS05405	COG2879	small protein
KQ257_RS05410	COG1966	Carbon starvation protein
KQ257_RS05430	COG4943	cyclic-guanylate-specific phosphodiesterase activity
KQ257_RS05455	COG1067	ATP-dependent peptidase activity
KQ257_RS05460	COG0583	DNA-binding transcription factor activity
KQ257_RS05485	COG1686	Belongs to the peptidase S11 family
KQ257_RS05490	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
KQ257_RS05525	COG0616	signal peptide processing
KQ257_RS05530	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
KQ257_RS05540	COG0573	inorganic phosphate transmembrane transporter activity
KQ257_RS05545	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
KQ257_RS05550	COG1113	amino acid transport
KQ257_RS05555	COG3961	Belongs to the TPP enzyme family
KQ257_RS05560	COG1522	sequence-specific DNA binding
KQ257_RS05570	COG0076	glutamate decarboxylase activity
KQ257_RS05575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ257_RS05590	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ257_RS05600	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ257_RS05635	COG0352	thiamine-phosphate diphosphorylase activity
KQ257_RS05660	COG0612	Peptidase, M16
KQ257_RS05670	COG1823	symporter activity
KQ257_RS05675	COG0583	DNA-binding transcription factor activity
KQ257_RS05680	COG0477	Major facilitator Superfamily
KQ257_RS05705	COG1187	pseudouridine synthase activity
KQ257_RS05720	COG1686	Belongs to the peptidase S11 family
KQ257_RS05725	COG1252	NADH dehydrogenase
KQ257_RS05735	COG0415	Belongs to the DNA photolyase family
KQ257_RS05750	COG1215	transferase activity, transferring glycosyl groups
KQ257_RS05780	COG2070	2-Nitropropane dioxygenase
KQ257_RS05835	COG0556	nucleotide-excision repair
KQ257_RS05855	COG0436	Aminotransferase
KQ257_RS05885	COG4221	oxidoreductase activity
KQ257_RS05895	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
KQ257_RS05900	COG1381	Involved in DNA repair and RecF pathway recombination
KQ257_RS05910	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
KQ257_RS05925	COG0681	Belongs to the peptidase S26 family
KQ257_RS05940	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
KQ257_RS05960	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
KQ257_RS05965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KQ257_RS05970	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
KQ257_RS05980	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
KQ257_RS05985	COG4208	sulfate ABC transporter
KQ257_RS05990	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
KQ257_RS05995	COG0583	DNA-binding transcription factor activity
KQ257_RS06000	COG4625	pathogenesis
KQ257_RS06015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
KQ257_RS06030	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
KQ257_RS06040	COG1051	belongs to the nudix hydrolase family
KQ257_RS06040	COG1056	cytidyltransferase-related domain
KQ257_RS06045	COG1024	Enoyl-CoA hydratase
KQ257_RS06060	COG2814	Major facilitator Superfamily
KQ257_RS06065	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KQ257_RS06065	COG0047	phosphoribosylformylglycinamidine synthase activity
KQ257_RS06085	COG1473	amidohydrolase
KQ257_RS06090	COG0824	Thioesterase
KQ257_RS06110	COG0823	Involved in the tonB-independent uptake of proteins
KQ257_RS06130	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ257_RS06165	COG0628	permease
KQ257_RS06175	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
KQ257_RS06180	COG0596	Alpha beta hydrolase
KQ257_RS06185	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
KQ257_RS06185	COG0616	signal peptide processing
KQ257_RS06195	COG2333	competence protein COMEC
KQ257_RS06195	COG0658	competence protein
KQ257_RS06200	COG1136	(ABC) transporter
KQ257_RS06205	COG4591	ABC-type transport system involved in lipoprotein release permease component
KQ257_RS06240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ257_RS06260	COG0463	Glycosyl transferase, family 2
KQ257_RS06290	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KQ257_RS06295	COG1280	lysine exporter protein (LysE YggA)
KQ257_RS06305	COG0019	diaminopimelate decarboxylase activity
KQ257_RS06315	COG1113	amino acid transport
KQ257_RS06330	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
KQ257_RS06340	COG3339	Conserved Protein
KQ257_RS06345	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
KQ257_RS06350	COG0243	molybdopterin cofactor binding
KQ257_RS06355	COG1929	Belongs to the glycerate kinase type-1 family
KQ257_RS06370	COG0778	Nitroreductase
KQ257_RS06390	COG3811	Belongs to the UPF0386 family
KQ257_RS06405	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS06425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KQ257_RS06445	COG0741	lytic transglycosylase activity
KQ257_RS06465	COG0584	glycerophosphoryl diester phosphodiesterase
KQ257_RS06470	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ257_RS06495	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KQ257_RS06500	COG1597	lipid kinase activity
KQ257_RS06515	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
KQ257_RS06520	COG0477	Major facilitator Superfamily
KQ257_RS06570	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
KQ257_RS06575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KQ257_RS06600	COG0505	Belongs to the CarA family
KQ257_RS06620	COG0251	oxidation-reduction process
KQ257_RS06630	COG0589	response to stress
KQ257_RS06645	COG2843	Capsule synthesis protein
KQ257_RS06665	COG2321	neutral zinc metallopeptidase
KQ257_RS06670	COG2354	Protein conserved in bacteria
KQ257_RS06690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
KQ257_RS06715	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KQ257_RS06720	COG1053	succinate dehydrogenase
KQ257_RS06725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
KQ257_RS06730	COG2009	succinate dehydrogenase
KQ257_RS06765	COG2921	Belongs to the UPF0250 family
KQ257_RS06770	COG0321	lipoyl(octanoyl) transferase activity
KQ257_RS06785	COG0531	amino acid
KQ257_RS06800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KQ257_RS06805	COG1648	precorrin-2 dehydrogenase activity
KQ257_RS06805	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
KQ257_RS06820	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
KQ257_RS06850	COG0671	phosphoesterase, PA-phosphatase related
KQ257_RS06855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ257_RS06865	COG1538	Outer membrane efflux protein
KQ257_RS06870	COG0393	Putative heavy-metal-binding
KQ257_RS06875	COG0393	Putative heavy-metal-binding
KQ257_RS06885	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS06895	COG0525	valine-tRNA ligase activity
KQ257_RS06915	COG0583	DNA-binding transcription factor activity
KQ257_RS06920	COG0004	ammonium transporteR
KQ257_RS06930	COG0642	Histidine kinase
KQ257_RS06935	COG0745	RESPONSE REGULATOR receiver
KQ257_RS06940	COG2194	sulfuric ester hydrolase activity
KQ257_RS06960	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ257_RS06975	COG2315	Protein conserved in bacteria
KQ257_RS06980	COG0142	geranyltranstransferase activity
KQ257_RS06985	COG2828	Protein conserved in bacteria
KQ257_RS06990	COG1113	amino acid transport
KQ257_RS07010	COG2207	Transcriptional regulator
KQ257_RS07035	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ257_RS07045	COG0560	Phosphoserine phosphatase
KQ257_RS07055	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
KQ257_RS07065	COG1530	ribonuclease E activity
KQ257_RS07070	COG0424	maF-like protein
KQ257_RS07075	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
KQ257_RS07080	COG1792	Involved in formation and maintenance of cell shape
KQ257_RS07085	COG1077	Cell shape determining protein MreB Mrl
KQ257_RS07090	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ257_RS07100	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
KQ257_RS07125	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
KQ257_RS07130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KQ257_RS07135	COG1752	Esterase of the alpha-beta hydrolase superfamily
KQ257_RS07140	COG1115	amino acid carrier protein
KQ257_RS07160	COG2814	Major facilitator Superfamily
KQ257_RS07165	COG1289	transmembrane transporter activity
KQ257_RS07175	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
KQ257_RS07215	COG1376	ErfK ybiS ycfS ynhG family protein
KQ257_RS07220	COG2832	Protein of unknown function (DUF454)
KQ257_RS07230	COG5510	response to toxic substance
KQ257_RS07245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KQ257_RS07260	COG0840	transmembrane signaling receptor activity
KQ257_RS07300	COG3422	double-strand break repair
KQ257_RS07305	COG2824	Alkylphosphonate utilization operon protein PhnA
KQ257_RS07310	COG3189	MarR family transcriptional regulator
KQ257_RS07320	COG0354	folic acid binding
KQ257_RS07325	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ257_RS07335	COG0679	Auxin Efflux Carrier
KQ257_RS07340	COG1902	pentaerythritol trinitrate reductase activity
KQ257_RS07345	COG4772	TonB-dependent receptor
KQ257_RS07350	COG2094	Belongs to the DNA glycosylase MPG family
KQ257_RS07375	COG1217	gtp-binding protein TYPA
KQ257_RS07380	COG2233	PERMEase
KQ257_RS07390	COG0833	amino acid
KQ257_RS07395	COG1690	Belongs to the RtcB family
KQ257_RS07405	COG2885	chlorophyll binding
KQ257_RS07405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
KQ257_RS07415	COG0183	Belongs to the thiolase family
KQ257_RS07435	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ257_RS07455	COG2207	Transcriptional regulator
KQ257_RS07460	COG0183	Belongs to the thiolase family
KQ257_RS07490	COG1272	protein, Hemolysin III
KQ257_RS07495	COG0477	Major facilitator Superfamily
KQ257_RS07510	COG0450	alkyl hydroperoxide reductase
KQ257_RS07530	COG0285	dihydrofolate synthase activity
KQ257_RS07580	COG2096	Adenosyltransferase
KQ257_RS07600	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
KQ257_RS07605	COG0745	RESPONSE REGULATOR receiver
KQ257_RS07610	COG2205	protein histidine kinase activity
KQ257_RS07620	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS07625	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS07670	COG0438	transferase activity, transferring glycosyl groups
KQ257_RS07675	COG1215	transferase activity, transferring glycosyl groups
KQ257_RS07680	COG0438	transferase activity, transferring glycosyl groups
KQ257_RS07700	COG0438	transferase activity, transferring glycosyl groups
KQ257_RS07705	COG0726	polysaccharide deacetylase
KQ257_RS07720	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
KQ257_RS07725	COG2205	protein histidine kinase activity
KQ257_RS07755	COG1862	Preprotein translocase
KQ257_RS07765	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
KQ257_RS07770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KQ257_RS07780	COG3781	membrane
KQ257_RS07785	COG0613	PHP domain protein
KQ257_RS07795	COG2350	Protein conserved in bacteria
KQ257_RS07825	COG1607	acyl-coa hydrolase
KQ257_RS07890	COG3293	Transposase
KQ257_RS07905	COG1408	metallophosphoesterase
KQ257_RS07910	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
KQ257_RS07920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KQ257_RS07940	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
KQ257_RS07945	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
KQ257_RS07950	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
KQ257_RS07960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
KQ257_RS07970	COG2969	positive regulation of protein catabolic process
KQ257_RS07990	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS07995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ257_RS08010	COG1309	transcriptional regulator
KQ257_RS08015	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS08060	COG1183	phosphatidylcholine synthase activity
KQ257_RS08065	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
KQ257_RS08095	COG0739	heme binding
KQ257_RS08095	COG0741	lytic transglycosylase activity
KQ257_RS08095	COG1196	nuclear chromosome segregation
KQ257_RS08105	COG1702	phosphate starvation-inducible protein PhoH
KQ257_RS08140	COG1295	ribonuclease BN
KQ257_RS08145	COG0697	spore germination
KQ257_RS08150	COG2169	Transcriptional regulator
KQ257_RS08155	COG0179	Fumarylacetoacetate (FAA) hydrolase
KQ257_RS08200	COG0557	exoribonuclease II activity
KQ257_RS08205	COG0339	signal peptide processing
KQ257_RS08210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
KQ257_RS08240	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
KQ257_RS08245	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS08400	COG0626	cystathionine gamma-synthase activity
KQ257_RS08405	COG0433	COG0433 Predicted ATPase
KQ257_RS08410	COG1017	nitric oxide dioxygenase activity
KQ257_RS08410	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ257_RS08415	COG1959	2 iron, 2 sulfur cluster binding
KQ257_RS08430	COG1301	dicarboxylic acid transport
KQ257_RS08435	COG1946	Acyl-CoA thioesterase
KQ257_RS08455	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
KQ257_RS08460	COG1040	competence protein
KQ257_RS08465	COG0494	nUDIX hydrolase
KQ257_RS08475	COG0598	Magnesium transport protein CorA
KQ257_RS08485	COG2854	intermembrane phospholipid transfer
KQ257_RS08495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
KQ257_RS08500	COG1127	ABC transporter
KQ257_RS08510	COG0513	Belongs to the DEAD box helicase family
KQ257_RS08530	COG0408	coproporphyrinogen oxidase activity
KQ257_RS08545	COG3293	Transposase
KQ257_RS08555	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS08565	COG1983	PspC domain protein
KQ257_RS08570	COG0517	IMP dehydrogenase activity
KQ257_RS08620	COG0583	DNA-binding transcription factor activity
KQ257_RS08660	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS08670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
KQ257_RS08675	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ257_RS08680	COG0833	amino acid
KQ257_RS08710	COG1192	Involved in chromosome partitioning
KQ257_RS08715	COG0628	permease
KQ257_RS08725	COG1289	transmembrane transporter activity
KQ257_RS08740	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ257_RS08745	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
KQ257_RS08755	COG0277	FAD linked oxidase domain protein
KQ257_RS08760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KQ257_RS08785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
KQ257_RS08790	COG5380	lipid catabolic process
KQ257_RS08810	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
KQ257_RS08860	COG0194	GDP metabolic process
KQ257_RS08875	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQ257_RS08895	COG3307	-O-antigen
KQ257_RS08925	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
KQ257_RS08930	COG1704	LemA family
KQ257_RS08940	COG0493	'glutamate synthase
KQ257_RS08945	COG0069	glutamate synthase activity
KQ257_RS08945	COG0070	glutamate synthase
KQ257_RS08945	COG0067	glutamate synthase
KQ257_RS08995	COG2226	methyltransferase
KQ257_RS09010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KQ257_RS09015	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
KQ257_RS09060	COG0833	amino acid
KQ257_RS09145	COG0488	(ABC) transporter
KQ257_RS09150	COG2873	o-acetylhomoserine
KQ257_RS09155	COG4221	oxidoreductase activity
KQ257_RS09160	COG0659	secondary active sulfate transmembrane transporter activity
KQ257_RS09185	COG0427	acetyl-CoA hydrolase
KQ257_RS09215	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
KQ257_RS09235	COG1132	(ABC) transporter
KQ257_RS09250	COG2329	Antibiotic biosynthesis monooxygenase
KQ257_RS09265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
KQ257_RS09340	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ257_RS09345	COG1733	regulation of RNA biosynthetic process
KQ257_RS09385	COG0667	Aldo Keto reductase
KQ257_RS09405	COG0583	DNA-binding transcription factor activity
KQ257_RS09410	COG2814	Major facilitator Superfamily
KQ257_RS09440	COG1335	isochorismatase
KQ257_RS09450	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS09455	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KQ257_RS09465	COG1113	amino acid transport
KQ257_RS09475	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KQ257_RS09490	COG2814	Major facilitator Superfamily
KQ257_RS09500	COG0351	phosphomethylpyrimidine kinase
KQ257_RS09500	COG0352	thiamine-phosphate diphosphorylase activity
KQ257_RS09500	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KQ257_RS09520	COG1309	transcriptional regulator
KQ257_RS09525	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
KQ257_RS09540	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ257_RS09550	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KQ257_RS09555	COG3162	membrane
KQ257_RS09560	COG2198	Histidine kinase
KQ257_RS09560	COG0784	Response regulator, receiver
KQ257_RS09560	COG2205	protein histidine kinase activity
KQ257_RS09585	COG1522	sequence-specific DNA binding
KQ257_RS09590	COG1335	isochorismatase
KQ257_RS09595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ257_RS09605	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS09615	COG0668	transmembrane transport
KQ257_RS09620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KQ257_RS09625	COG1519	Transferase
KQ257_RS09630	COG1902	pentaerythritol trinitrate reductase activity
KQ257_RS09650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
KQ257_RS09675	COG0426	domain, Protein
KQ257_RS09675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ257_RS09680	COG4774	siderophore transport
KQ257_RS09685	COG2119	membrane
KQ257_RS09695	COG0508	dehydrogenase complex catalyzes the overall conversion of
KQ257_RS09705	COG4942	peptidase
KQ257_RS09720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KQ257_RS09730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
KQ257_RS09750	COG0189	ligase activity
KQ257_RS09770	COG0708	Exodeoxyribonuclease III
KQ257_RS09775	COG1393	Belongs to the ArsC family
KQ257_RS09790	COG3706	GGDEF domain
KQ257_RS09825	COG2351	hydroxyisourate hydrolase activity
KQ257_RS09830	COG2233	PERMEase
KQ257_RS09840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ257_RS09850	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
KQ257_RS09855	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS09865	COG3150	esterase
KQ257_RS09900	COG2918	glutathione biosynthetic process
KQ257_RS09915	COG2733	membrane
KQ257_RS09920	COG0436	Aminotransferase
KQ257_RS09925	COG0534	Mate efflux family protein
KQ257_RS09985	COG0753	catalase activity
KQ257_RS10030	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
KQ257_RS10035	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
KQ257_RS10045	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KQ257_RS10050	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ257_RS10065	COG0010	Belongs to the arginase family
KQ257_RS10095	COG2188	Transcriptional regulator
KQ257_RS10105	COG3293	Transposase
KQ257_RS10110	COG0523	cobalamin synthesis protein
KQ257_RS10120	COG1113	amino acid transport
KQ257_RS10130	COG0625	glutathione transferase activity
KQ257_RS10150	COG1683	Conserved Protein
KQ257_RS10155	COG0534	Mate efflux family protein
KQ257_RS10160	COG0385	Bile acid
KQ257_RS10165	COG1335	isochorismatase
KQ257_RS10170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ257_RS10190	COG2116	formate transmembrane transporter activity
KQ257_RS10195	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
KQ257_RS10200	COG2133	pyrroloquinoline quinone binding
KQ257_RS10205	COG2983	Belongs to the UPF0260 family
KQ257_RS10215	COG0400	carboxylic ester hydrolase activity
KQ257_RS10225	COG1194	a g-specific adenine glycosylase
KQ257_RS10240	COG2818	Glycosylase
KQ257_RS10245	COG1064	alcohol dehydrogenase
KQ257_RS10250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ257_RS10265	COG0583	DNA-binding transcription factor activity
KQ257_RS10270	COG0656	L-ascorbic acid biosynthetic process
KQ257_RS10275	COG2814	Major facilitator Superfamily
KQ257_RS10310	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
KQ257_RS10325	COG2233	PERMEase
KQ257_RS10330	COG0583	DNA-binding transcription factor activity
KQ257_RS10355	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
KQ257_RS10365	COG0733	neurotransmitter:sodium symporter activity
KQ257_RS10405	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KQ257_RS10410	COG0657	acetylesterase activity
KQ257_RS10430	COG0583	DNA-binding transcription factor activity
KQ257_RS10460	COG2951	lytic endotransglycosylase activity
KQ257_RS10465	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KQ257_RS10480	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
KQ257_RS10490	COG0671	phosphoesterase, PA-phosphatase related
KQ257_RS10495	COG0861	Integral membrane protein TerC family
KQ257_RS10505	COG0754	glutathionylspermidine amidase activity
KQ257_RS10515	COG0402	S-adenosylhomocysteine deaminase activity
KQ257_RS10530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ257_RS10535	COG1230	cation diffusion facilitator family transporter
KQ257_RS10595	COG0582	viral genome integration into host DNA
KQ257_RS10605	COG0706	membrane insertase activity
KQ257_RS10630	COG0592	DNA-directed DNA polymerase activity
KQ257_RS10640	COG0187	DNA topoisomerase II activity
KQ257_RS10650	COG0586	Pfam SNARE associated Golgi protein
KQ257_RS10655	COG0488	(ABC) transporter
KQ257_RS10680	COG0596	Alpha beta hydrolase
KQ257_RS10685	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
KQ257_RS10690	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
KQ257_RS10730	COG1047	Peptidyl-prolyl cis-trans
KQ257_RS10740	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
KQ257_RS10745	COG0196	riboflavin kinase activity
KQ257_RS10755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
KQ257_RS10760	COG1309	transcriptional regulator
KQ257_RS10765	COG1116	anion transmembrane transporter activity
KQ257_RS10770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ257_RS10775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ257_RS10780	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ257_RS10785	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
KQ257_RS10805	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS10810	COG0546	phosphoglycolate phosphatase activity
KQ257_RS10865	COG3023	N-Acetylmuramoyl-L-alanine amidase
KQ257_RS10870	COG0728	peptidoglycan biosynthetic process
KQ257_RS10900	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
KQ257_RS10930	COG0438	transferase activity, transferring glycosyl groups
KQ257_RS10950	COG1216	Glycosyl transferase, family 2
KQ257_RS10955	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KQ257_RS10960	COG1210	Utp--glucose-1-phosphate uridylyltransferase
KQ257_RS10975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KQ257_RS10985	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ257_RS10995	COG2186	Transcriptional regulator
KQ257_RS11005	COG0277	FAD linked oxidase domain protein
KQ257_RS11010	COG1448	Aminotransferase
KQ257_RS11020	COG1802	Transcriptional regulator
KQ257_RS11035	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KQ257_RS11055	COG1051	belongs to the nudix hydrolase family
KQ257_RS11090	COG0564	pseudouridine synthase activity
KQ257_RS11130	COG0251	oxidation-reduction process
KQ257_RS11135	COG1113	amino acid transport
KQ257_RS11140	COG1113	amino acid transport
KQ257_RS11160	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
KQ257_RS11165	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS11170	COG1024	Enoyl-CoA hydratase
KQ257_RS11175	COG1024	Enoyl-CoA hydratase
KQ257_RS11180	COG0477	Major facilitator Superfamily
KQ257_RS11185	COG3916	Acyl-homoserine-lactone synthase
KQ257_RS11195	COG2197	response regulator
KQ257_RS11205	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS11210	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
KQ257_RS11210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
KQ257_RS11210	COG3321	synthase
KQ257_RS11210	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
KQ257_RS11250	COG0271	Belongs to the BolA IbaG family
KQ257_RS11260	COG1192	Involved in chromosome partitioning
KQ257_RS11275	COG0586	Pfam SNARE associated Golgi protein
KQ257_RS11280	COG2259	Doxx family
KQ257_RS11285	COG4399	Belongs to the UPF0754 family
KQ257_RS11290	COG0518	GMP synthase (glutamine-hydrolyzing) activity
KQ257_RS11290	COG0519	Catalyzes the synthesis of GMP from XMP
KQ257_RS11335	COG0281	malic enzyme
KQ257_RS11345	COG2837	iron assimilation
KQ257_RS11350	COG1280	lysine exporter protein (LysE YggA)
KQ257_RS11355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
KQ257_RS11360	COG1121	(ABC) transporter
KQ257_RS11430	COG0386	Belongs to the glutathione peroxidase family
KQ257_RS11445	COG1309	transcriptional regulator
KQ257_RS11450	COG0697	spore germination
KQ257_RS11460	COG0758	DNA mediated transformation
KQ257_RS11530	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
KQ257_RS11540	COG0655	NAD(P)H dehydrogenase (quinone) activity
KQ257_RS11580	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ257_RS11590	COG2814	Major facilitator Superfamily
KQ257_RS11600	COG1253	flavin adenine dinucleotide binding
KQ257_RS11610	COG2860	membrane
KQ257_RS11615	COG0477	Major facilitator Superfamily
KQ257_RS11625	COG0318	PFAM AMP-dependent synthetase and ligase
KQ257_RS11640	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KQ257_RS11660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ257_RS11670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ257_RS11705	COG3328	transposase activity
KQ257_RS11720	COG0589	response to stress
KQ257_RS11725	COG0659	secondary active sulfate transmembrane transporter activity
KQ257_RS11745	COG0347	Belongs to the P(II) protein family
KQ257_RS11750	COG0004	ammonium transporteR
KQ257_RS11760	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ257_RS11760	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
KQ257_RS11800	COG0795	lipopolysaccharide-transporting ATPase activity
KQ257_RS11805	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
KQ257_RS11810	COG0793	Belongs to the peptidase S41A family
KQ257_RS11825	COG2197	response regulator
KQ257_RS11835	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
KQ257_RS11845	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ257_RS11850	COG4974	Belongs to the 'phage' integrase family
KQ257_RS11875	COG0772	Belongs to the SEDS family
KQ257_RS11880	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
KQ257_RS11885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
KQ257_RS11890	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
KQ257_RS11915	COG0697	spore germination
KQ257_RS11920	COG1538	Outer membrane efflux protein
KQ257_RS11940	COG3275	phosphorelay sensor kinase activity
KQ257_RS11950	COG0181	hydroxymethylbilane synthase activity
KQ257_RS11995	COG1716	ATPase activity
KQ257_RS12000	COG0546	phosphoglycolate phosphatase activity
KQ257_RS12100	COG2056	Na+-H+ antiporter family
KQ257_RS12115	COG0326	Molecular chaperone. Has ATPase activity
KQ257_RS12130	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
KQ257_RS12175	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS12205	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KQ257_RS12210	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ257_RS12210	COG2169	Transcriptional regulator
KQ257_RS12240	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
KQ257_RS12250	COG0497	DNA recombination
KQ257_RS12265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KQ257_RS12275	COG0237	dephospho-CoA kinase activity
KQ257_RS12280	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KQ257_RS12330	COG0195	Participates in both transcription termination and antitermination
KQ257_RS12345	COG1320	monovalent cation:proton antiporter activity
KQ257_RS12350	COG2212	antiporter activity
KQ257_RS12355	COG1863	multisubunit Na H antiporter MnhE subunit
KQ257_RS12360	COG0651	ATP synthesis coupled electron transport
KQ257_RS12365	COG1006	Multisubunit Na H antiporter MnhC subunit
KQ257_RS12370	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQ257_RS12370	COG2111	Na H antiporter
KQ257_RS12385	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
KQ257_RS12405	COG2226	methyltransferase
KQ257_RS12425	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
KQ257_RS12430	COG1074	ATP-dependent DNA helicase activity
KQ257_RS12435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KQ257_RS12440	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
KQ257_RS12455	COG0598	Magnesium transport protein CorA
KQ257_RS12460	COG0789	Transcriptional regulator
KQ257_RS12465	COG0484	heat shock protein binding
KQ257_RS12480	COG0475	glutathione-regulated potassium exporter activity
KQ257_RS12480	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ257_RS12485	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KQ257_RS12505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ257_RS12515	COG4535	Mg2 and Co2 transporter CorC
KQ257_RS12520	COG0425	Belongs to the sulfur carrier protein TusA family
KQ257_RS12530	COG0644	oxidoreductase
KQ257_RS12530	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
KQ257_RS12540	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
KQ257_RS12555	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
KQ257_RS12560	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
KQ257_RS12570	COG0493	'glutamate synthase
KQ257_RS12570	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ257_RS12600	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
KQ257_RS12615	COG0534	Mate efflux family protein
KQ257_RS12625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
KQ257_RS12630	COG4221	oxidoreductase activity
KQ257_RS12635	COG0583	DNA-binding transcription factor activity
KQ257_RS12650	COG0318	PFAM AMP-dependent synthetase and ligase
KQ257_RS12655	COG1530	ribonuclease E activity
KQ257_RS12665	COG0546	phosphoglycolate phosphatase activity
KQ257_RS12670	COG2378	regulation of single-species biofilm formation
KQ257_RS12675	COG0625	glutathione transferase activity
KQ257_RS12685	COG0583	DNA-binding transcription factor activity
KQ257_RS12740	COG0473	3-isopropylmalate dehydrogenase activity
KQ257_RS12795	COG1301	dicarboxylic acid transport
KQ257_RS12805	COG1560	Kdo2-lipid A biosynthetic process
KQ257_RS12810	COG1280	lysine exporter protein (LysE YggA)
KQ257_RS12815	COG0488	(ABC) transporter
KQ257_RS12820	COG2900	Belongs to the SlyX family
KQ257_RS12830	COG1733	regulation of RNA biosynthetic process
KQ257_RS12855	COG0210	DNA helicase
KQ257_RS12860	COG0724	RNA recognition motif
KQ257_RS12880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KQ257_RS12880	COG4651	solute:proton antiporter activity
KQ257_RS12905	COG0788	formyltetrahydrofolate deformylase activity
KQ257_RS13005	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ257_RS13005	COG2813	Specifically methylates the guanine in position
KQ257_RS13015	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQ257_RS13025	COG4774	siderophore transport
KQ257_RS13035	COG0740	serine-type endopeptidase activity
KQ257_RS13055	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
KQ257_RS13055	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KQ257_RS13060	COG0857	belongs to the CobB CobQ family
KQ257_RS13060	COG0280	phosphate acetyltransferase
KQ257_RS13065	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KQ257_RS13075	COG0800	Aldolase
KQ257_RS13085	COG3265	gluconokinase activity
KQ257_RS13090	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS13100	COG2267	carboxylic ester hydrolase activity
KQ257_RS13115	COG0793	Belongs to the peptidase S41A family
KQ257_RS13150	COG1426	Protein conserved in bacteria
KQ257_RS13190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KQ257_RS13200	COG1162	GTPase activity
KQ257_RS13205	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
KQ257_RS13220	COG1538	Outer membrane efflux protein
KQ257_RS13225	COG0577	efflux transmembrane transporter activity
KQ257_RS13225	COG1136	(ABC) transporter
KQ257_RS13255	COG0028	Belongs to the TPP enzyme family
KQ257_RS13260	COG0440	acetolactate synthase activity
KQ257_RS13290	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
KQ257_RS13305	COG0084	hydrolase, TatD family'
KQ257_RS13315	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
KQ257_RS13325	COG0583	DNA-binding transcription factor activity
KQ257_RS13335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ257_RS13340	COG2814	Major facilitator Superfamily
KQ257_RS13350	COG0697	spore germination
KQ257_RS13380	COG3622	Belongs to the hyi family
KQ257_RS13385	COG2084	Dehydrogenase
KQ257_RS13390	COG1024	Enoyl-CoA hydratase
KQ257_RS13395	COG0784	Response regulator, receiver
KQ257_RS13395	COG2205	protein histidine kinase activity
KQ257_RS13395	COG5002	protein histidine kinase activity
KQ257_RS13415	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KQ257_RS13420	COG4221	oxidoreductase activity
KQ257_RS13425	COG3956	TIGRFAM MazG family protein
KQ257_RS13430	COG1555	photosystem II stabilization
KQ257_RS13435	COG0617	tRNA 3'-terminal CCA addition
KQ257_RS13440	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
KQ257_RS13460	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
KQ257_RS13465	COG3028	Belongs to the UPF0307 family
KQ257_RS13475	COG0582	viral genome integration into host DNA
KQ257_RS13545	COG0625	glutathione transferase activity
KQ257_RS13550	COG1238	metal cluster binding
KQ257_RS13590	COG3328	transposase activity
KQ257_RS13605	COG0072	phenylalanine-tRNA ligase activity
KQ257_RS13635	COG0248	Ppx GppA phosphatase
KQ257_RS13645	COG0037	tRNA processing
KQ257_RS13685	COG1764	response to oxidative stress
KQ257_RS13690	COG1846	Transcriptional regulator
KQ257_RS13700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ257_RS13760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KQ257_RS13765	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
KQ257_RS13770	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
KQ257_RS13780	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
KQ257_RS13820	COG1214	PFAM Peptidase M22, glycoprotease
KQ257_RS13845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KQ257_RS13850	COG0561	phosphatase activity
KQ257_RS13860	COG2132	Multicopper oxidase
KQ257_RS13880	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
KQ257_RS13885	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
KQ257_RS13890	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
KQ257_RS13920	COG1063	alcohol dehydrogenase
KQ257_RS13925	COG0583	DNA-binding transcription factor activity
KQ257_RS13930	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS13935	COG2814	Major facilitator Superfamily
KQ257_RS13940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQ257_RS13950	COG1053	succinate dehydrogenase
KQ257_RS13955	COG0583	DNA-binding transcription factor activity
KQ257_RS13970	COG0583	DNA-binding transcription factor activity
KQ257_RS14005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ257_RS14015	COG0419	ATPase involved in DNA repair
KQ257_RS14035	COG3328	transposase activity
KQ257_RS14045	COG0384	phenazine biosynthesis protein PhzF
KQ257_RS14060	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KQ257_RS14080	COG0745	RESPONSE REGULATOR receiver
KQ257_RS14120	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
KQ257_RS14150	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
KQ257_RS14155	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
KQ257_RS14175	COG0583	DNA-binding transcription factor activity
KQ257_RS14195	COG0668	transmembrane transport
KQ257_RS14205	COG2081	HI0933 family
KQ257_RS14210	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KQ257_RS14240	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ257_RS14240	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
KQ257_RS14250	COG0489	protein tyrosine kinase activity
KQ257_RS14300	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
KQ257_RS14310	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
KQ257_RS14325	COG0730	response to heat
KQ257_RS14340	COG1196	nuclear chromosome segregation
KQ257_RS14360	COG2223	nitrite transmembrane transporter activity
KQ257_RS14365	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
KQ257_RS14370	COG1877	trehalose-phosphatase activity
KQ257_RS14375	COG2226	methyltransferase
KQ257_RS14375	COG0596	Alpha beta hydrolase
KQ257_RS14375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
KQ257_RS14390	COG4106	trans-aconitate 2-methyltransferase activity
KQ257_RS14405	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
KQ257_RS14410	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
KQ257_RS14415	COG0009	L-threonylcarbamoyladenylate synthase
KQ257_RS14420	COG3101	peptidyl-lysine hydroxylation
KQ257_RS14425	COG1399	metal-binding, possibly nucleic acid-binding protein
KQ257_RS14450	COG1652	LysM domain
KQ257_RS14455	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KQ257_RS14455	COG0352	thiamine-phosphate diphosphorylase activity
KQ257_RS14455	COG0351	phosphomethylpyrimidine kinase
KQ257_RS14465	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
KQ257_RS14495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
KQ257_RS14525	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
KQ257_RS14540	COG0358	DNA primase activity
KQ257_RS14550	COG0564	pseudouridine synthase activity
KQ257_RS14575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
KQ257_RS14595	COG0583	DNA-binding transcription factor activity
KQ257_RS14600	COG0473	3-isopropylmalate dehydrogenase activity
KQ257_RS14610	COG0657	acetylesterase activity
KQ257_RS14620	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS14640	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
KQ257_RS14640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
KQ257_RS14655	COG1981	membrane
KQ257_RS14700	COG0456	acetyltransferase
KQ257_RS14710	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
KQ257_RS14715	COG0492	ferredoxin-NADP+ reductase activity
KQ257_RS14720	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
KQ257_RS14720	COG1674	ftsk spoiiie
KQ257_RS14725	COG1280	lysine exporter protein (LysE YggA)
KQ257_RS14745	COG2894	cell division
KQ257_RS14760	COG0204	Acyl-transferase
KQ257_RS14765	COG2885	chlorophyll binding
KQ257_RS14770	COG0210	DNA helicase
KQ257_RS14780	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
KQ257_RS14795	COG0121	glutamine amidotransferase
KQ257_RS14815	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
KQ257_RS14820	COG0735	belongs to the Fur family
KQ257_RS14845	COG0420	3'-5' exonuclease activity
KQ257_RS14865	COG1090	epimerase
KQ257_RS14880	COG2050	protein possibly involved in aromatic compounds catabolism
KQ257_RS14890	COG2814	Major facilitator Superfamily
KQ257_RS14895	COG0405	Gamma-glutamyltransferase
KQ257_RS14905	COG0582	viral genome integration into host DNA
KQ257_RS14970	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KQ257_RS15000	COG0477	Major facilitator Superfamily
KQ257_RS15005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ257_RS15015	COG1595	DNA-templated transcription, initiation
KQ257_RS15070	COG0531	amino acid
KQ257_RS15075	COG2040	homocysteine
KQ257_RS15100	COG1309	transcriptional regulator
KQ257_RS15105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ257_RS15110	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
KQ257_RS15120	COG1607	acyl-coa hydrolase
KQ257_RS15130	COG0523	cobalamin synthesis protein
KQ257_RS15140	COG4681	YaeQ
KQ257_RS15150	COG1649	PFAM Uncharacterised BCR, COG1649
KQ257_RS15150	COG0726	polysaccharide deacetylase
KQ257_RS15155	COG1215	transferase activity, transferring glycosyl groups
KQ257_RS15180	COG1414	Transcriptional regulator
KQ257_RS15215	COG2271	Major facilitator Superfamily
KQ257_RS15225	COG2267	carboxylic ester hydrolase activity
KQ257_RS15230	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS15245	COG0028	Belongs to the TPP enzyme family
KQ257_RS15255	COG0477	Major facilitator Superfamily
KQ257_RS15260	COG0242	peptide deformylase activity
KQ257_RS15265	COG2066	Belongs to the glutaminase family
KQ257_RS15270	COG2207	Transcriptional regulator
KQ257_RS15275	COG2223	nitrite transmembrane transporter activity
KQ257_RS15290	COG0583	DNA-binding transcription factor activity
KQ257_RS15295	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS15300	COG2271	Major facilitator Superfamily
KQ257_RS15305	COG3959	Transketolase, thiamine diphosphate binding domain
KQ257_RS15310	COG3958	Transketolase
KQ257_RS15320	COG0306	phosphate transporter
KQ257_RS15340	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KQ257_RS15385	COG4181	ATPase activity
KQ257_RS15390	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
KQ257_RS15415	COG0583	DNA-binding transcription factor activity
KQ257_RS15425	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
KQ257_RS15430	COG1773	rubredoxin
KQ257_RS15485	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS15490	COG1253	flavin adenine dinucleotide binding
KQ257_RS15530	COG0804	urea catabolic process
KQ257_RS15540	COG0830	nickel cation binding
KQ257_RS15555	COG0742	ribosomal rna small subunit methyltransferase
KQ257_RS15560	COG0768	penicillin binding
KQ257_RS15585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
KQ257_RS15590	COG2878	Part of a membrane complex involved in electron transport
KQ257_RS15595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KQ257_RS15605	COG3384	dioxygenase
KQ257_RS15620	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS15630	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS15645	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KQ257_RS15685	COG0006	proline dipeptidase activity
KQ257_RS15690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ257_RS15695	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ257_RS15715	COG1279	arginine transmembrane transporter activity
KQ257_RS15720	COG0583	DNA-binding transcription factor activity
KQ257_RS15760	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ257_RS15765	COG0741	lytic transglycosylase activity
KQ257_RS15765	COG0741	lytic transglycosylase activity
KQ257_RS15765	COG1388	LysM domain
KQ257_RS15765	COG1388	LysM domain
KQ257_RS15770	COG4166	transmembrane transport
KQ257_RS15775	COG4174	ABC transporter (Permease)
KQ257_RS15780	COG4239	(ABC) transporter, permease
KQ257_RS15785	COG4172	Belongs to the ABC transporter superfamily
KQ257_RS15805	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KQ257_RS15815	COG2203	Gaf domain
KQ257_RS15815	COG3706	GGDEF domain
KQ257_RS15815	COG4251	negative regulation of phosphorylation
KQ257_RS15815	COG5001	Diguanylate cyclase
KQ257_RS15825	COG0446	pyridine nucleotide-disulphide oxidoreductase
KQ257_RS15825	COG1902	pentaerythritol trinitrate reductase activity
KQ257_RS15835	COG0582	viral genome integration into host DNA
KQ257_RS15850	COG3328	transposase activity
KQ257_RS15920	COG0789	Transcriptional regulator
KQ257_RS15980	COG2184	nucleotidyltransferase activity
KQ257_RS15990	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KQ257_RS16015	COG1309	transcriptional regulator
KQ257_RS16030	COG4269	membrane
KQ257_RS16055	COG3209	COG3209 Rhs family protein
KQ257_RS16085	COG1113	amino acid transport
KQ257_RS16095	COG0531	amino acid
KQ257_RS16115	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS16135	COG1113	amino acid transport
KQ257_RS16150	COG0697	spore germination
KQ257_RS16155	COG2721	sulfolactate sulfo-lyase activity
KQ257_RS16160	COG2271	Major facilitator Superfamily
KQ257_RS16165	COG4948	Mandelate Racemase Muconate Lactonizing
KQ257_RS16175	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS16180	COG2186	Transcriptional regulator
KQ257_RS16205	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS16215	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS16220	COG1024	Enoyl-CoA hydratase
KQ257_RS16225	COG2814	Major facilitator Superfamily
KQ257_RS16240	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ257_RS16255	COG1262	PFAM Formylglycine-generating sulfatase enzyme
KQ257_RS16300	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
KQ257_RS16315	COG0583	DNA-binding transcription factor activity
KQ257_RS16320	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
KQ257_RS16325	COG2072	flavoprotein involved in K transport
KQ257_RS16330	COG0300	oxidoreductase activity
KQ257_RS16340	COG1309	transcriptional regulator
KQ257_RS16345	COG1741	Belongs to the pirin family
KQ257_RS16360	COG2072	flavoprotein involved in K transport
KQ257_RS16370	COG2252	PERMEase
KQ257_RS16375	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KQ257_RS16380	COG3038	cytochrome b561
KQ257_RS16390	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KQ257_RS16400	COG0527	aspartate kinase activity
KQ257_RS16455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ257_RS16460	COG4197	protein conserved in bacteria, prophage-related
KQ257_RS16550	COG5410	chromosome segregation
KQ257_RS16555	COG3567	Phage-associated protein, HI1409 family
KQ257_RS16570	COG3566	protein conserved in bacteria
KQ257_RS16690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ257_RS16695	COG0582	viral genome integration into host DNA
KQ257_RS16705	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
KQ257_RS16715	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
KQ257_RS16730	COG0667	Aldo Keto reductase
KQ257_RS16745	COG1765	OsmC-like protein
KQ257_RS16750	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
KQ257_RS16760	COG0542	response to heat
KQ257_RS16795	COG2885	chlorophyll binding
KQ257_RS16805	COG0625	glutathione transferase activity
KQ257_RS16810	COG0220	tRNA (guanine-N7-)-methyltransferase activity
KQ257_RS16830	COG3634	alkyl hydroperoxide reductase activity
KQ257_RS16840	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
KQ257_RS16850	COG0450	alkyl hydroperoxide reductase
KQ257_RS16855	COG1643	Atp-dependent helicase
KQ257_RS16870	COG2814	Major facilitator Superfamily
KQ257_RS16875	COG3135	benzoate transporter
KQ257_RS16880	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS16885	COG0543	2 iron, 2 sulfur cluster binding
KQ257_RS16885	COG0633	Ferredoxin
KQ257_RS16895	COG4638	Rieske (2fe-2S)
KQ257_RS16905	COG0583	DNA-binding transcription factor activity
KQ257_RS16955	COG1570	exodeoxyribonuclease VII activity
KQ257_RS16985	COG1280	lysine exporter protein (LysE YggA)
KQ257_RS16990	COG1278	Cold shock
KQ257_RS17020	COG2814	Major facilitator Superfamily
KQ257_RS17145	COG3728	DNA packaging
KQ257_RS17145	COG5484	DNA packaging
KQ257_RS17295	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
KQ257_RS17295	COG0517	IMP dehydrogenase activity
KQ257_RS17300	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
KQ257_RS17310	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
KQ257_RS17315	COG1137	ATPase activity
KQ257_RS17320	COG1538	Outer membrane efflux protein
KQ257_RS17350	COG4122	O-methyltransferase activity
KQ257_RS17360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
KQ257_RS17375	COG1522	sequence-specific DNA binding
KQ257_RS17380	COG5006	permease, DMT superfamily
KQ257_RS17390	COG1560	Kdo2-lipid A biosynthetic process
KQ257_RS17405	COG2814	Major facilitator Superfamily
KQ257_RS17415	COG2515	1-aminocyclopropane-1-carboxylate deaminase
KQ257_RS17420	COG1116	anion transmembrane transporter activity
KQ257_RS17425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ257_RS17430	COG4521	taurine ABC transporter
KQ257_RS17450	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ257_RS17490	COG3209	COG3209 Rhs family protein
KQ257_RS17525	COG0583	DNA-binding transcription factor activity
KQ257_RS17530	COG1914	H( )-stimulated, divalent metal cation uptake system
KQ257_RS17550	COG4770	biotin carboxylase activity
KQ257_RS17555	COG0038	chloride channel
KQ257_RS17575	COG1063	alcohol dehydrogenase
KQ257_RS17590	COG0439	Biotin carboxylase
KQ257_RS17595	COG2249	NAD(P)H dehydrogenase (quinone) activity
KQ257_RS17600	COG1733	regulation of RNA biosynthetic process
KQ257_RS17615	COG0864	Transcriptional regulator
KQ257_RS17625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ257_RS17630	COG1116	anion transmembrane transporter activity
KQ257_RS17750	COG0590	tRNA wobble adenosine to inosine editing
KQ257_RS17755	COG2807	transmembrane transport
KQ257_RS17770	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
KQ257_RS17780	COG0789	Transcriptional regulator
KQ257_RS17790	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KQ257_RS17810	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
KQ257_RS17835	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS17840	COG0531	amino acid
KQ257_RS17845	COG1760	l-serine dehydratase
KQ257_RS17850	COG2030	dehydratase
KQ257_RS17850	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS17855	COG3396	Phenylacetate-CoA oxygenase
KQ257_RS17860	COG3460	Phenylacetate-CoA oxygenase
KQ257_RS17865	COG3396	Phenylacetate-CoA oxygenase
KQ257_RS17870	COG2151	metal-sulfur cluster biosynthetic enzyme
KQ257_RS17875	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
KQ257_RS17880	COG1024	Enoyl-CoA hydratase
KQ257_RS17885	COG1024	Enoyl-CoA hydratase
KQ257_RS17890	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ257_RS17895	COG0183	Belongs to the thiolase family
KQ257_RS17900	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
KQ257_RS17905	COG3327	negative regulation of DNA-templated transcription, initiation
KQ257_RS17915	COG2050	protein possibly involved in aromatic compounds catabolism
KQ257_RS17925	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS17960	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS17985	COG1804	L-carnitine dehydratase bile acid-inducible protein F
KQ257_RS17990	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
KQ257_RS17995	COG2271	Major facilitator Superfamily
KQ257_RS18000	COG0753	catalase activity
KQ257_RS18005	COG3038	cytochrome b561
KQ257_RS18025	COG2267	carboxylic ester hydrolase activity
KQ257_RS18030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
KQ257_RS18035	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
KQ257_RS18040	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS18050	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KQ257_RS18060	COG1012	belongs to the aldehyde dehydrogenase family
KQ257_RS18065	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
KQ257_RS18070	COG0583	DNA-binding transcription factor activity
KQ257_RS18080	COG1414	Transcriptional regulator
KQ257_RS18085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
KQ257_RS18100	COG1840	ABC-type Fe3 transport system, periplasmic component
KQ257_RS18105	COG3842	ATPase activity
KQ257_RS18120	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
KQ257_RS18125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KQ257_RS18130	COG2814	Major facilitator Superfamily
KQ257_RS18135	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS18150	COG1024	Enoyl-CoA hydratase
KQ257_RS18160	COG2814	Major facilitator Superfamily
KQ257_RS18170	COG0183	Belongs to the thiolase family
KQ257_RS18175	COG1250	3-hydroxyacyl-CoA dehydrogenase
KQ257_RS18180	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS18185	COG1024	Enoyl-CoA hydratase
KQ257_RS18190	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS18195	COG2814	Major facilitator Superfamily
KQ257_RS18200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
KQ257_RS18205	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
KQ257_RS18215	COG2814	Major facilitator Superfamily
KQ257_RS18225	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS18240	COG0583	DNA-binding transcription factor activity
KQ257_RS18250	COG4770	biotin carboxylase activity
KQ257_RS18255	COG1024	Enoyl-CoA hydratase
KQ257_RS18260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KQ257_RS18265	COG1960	acyl-CoA dehydrogenase activity
KQ257_RS18270	COG1309	transcriptional regulator
KQ257_RS18275	COG0318	PFAM AMP-dependent synthetase and ligase
KQ257_RS18295	COG3328	transposase activity
KQ257_RS18305	COG0583	DNA-binding transcription factor activity
KQ257_RS18355	COG1028	Short-chain dehydrogenase reductase Sdr
KQ257_RS18375	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
KQ257_RS18395	COG0784	Response regulator, receiver
KQ257_RS18395	COG2205	protein histidine kinase activity
KQ257_RS18415	COG0765	amino acid transport
KQ257_RS18420	COG0765	amino acid transport
KQ257_RS18425	COG1126	abc transporter atp-binding protein
KQ257_RS18430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ257_RS18435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KQ257_RS18450	COG1280	lysine exporter protein (LysE YggA)
KQ257_RS18455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
KQ257_RS18460	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
KQ257_RS18465	COG1045	serine acetyltransferase
KQ257_RS18480	COG0583	DNA-binding transcription factor activity
KQ257_RS18485	COG0625	glutathione transferase activity
KQ257_RS18490	COG0625	glutathione transferase activity
KQ257_RS18495	COG0583	DNA-binding transcription factor activity
KQ257_RS18505	COG1346	cytolysis
KQ257_RS18525	COG2814	Major facilitator Superfamily
KQ257_RS18535	COG0583	DNA-binding transcription factor activity
KQ257_RS18545	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
KQ257_RS18550	COG3052	prosthetic group binding
KQ257_RS18570	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
KQ257_RS18590	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
KQ257_RS18600	COG1294	oxidase, subunit
KQ257_RS18605	COG1271	oxidase subunit
KQ257_RS18625	COG0477	Major facilitator Superfamily
KQ257_RS18635	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS18640	COG4521	taurine ABC transporter
KQ257_RS18645	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
KQ257_RS18650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KQ257_RS18655	COG2175	clavaminate synthase activity
KQ257_RS18665	COG1953	Uracil, thiamine, allantoin
KQ257_RS18675	COG0583	DNA-binding transcription factor activity
KQ257_RS18685	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
KQ257_RS18700	COG0640	Transcriptional regulator
KQ257_RS18705	COG0798	PFAM Bile acid sodium symporter
KQ257_RS18710	COG0583	DNA-binding transcription factor activity
KQ257_RS18725	COG3634	alkyl hydroperoxide reductase activity
KQ257_RS18765	COG0436	Aminotransferase
KQ257_RS18775	COG0386	Belongs to the glutathione peroxidase family
KQ257_RS18785	COG3328	transposase activity
KQ257_RS18825	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KQ257_RS18850	COG0012	GTP binding
KQ257_RS18855	COG2011	ABC-type metal ion transport system permease component
KQ257_RS18860	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KQ257_RS18870	COG1464	Belongs to the NlpA lipoprotein family
KQ257_RS18900	COG0765	amino acid transport
KQ257_RS18905	COG0765	amino acid transport
KQ257_RS18910	COG1126	abc transporter atp-binding protein
KQ257_RS18920	COG1522	sequence-specific DNA binding
KQ257_RS18935	COG1309	transcriptional regulator
KQ257_RS18955	COG0583	DNA-binding transcription factor activity
KQ257_RS18965	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
KQ257_RS18975	COG0697	spore germination
KQ257_RS19000	COG3121	Chaperone
KQ257_RS19005	COG3539	Fimbrial protein
KQ257_RS19030	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
KQ257_RS19030	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
KQ257_RS19110	COG1525	nuclease
KQ257_RS19160	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
KQ257_RS19185	COG0583	DNA-binding transcription factor activity
KQ257_RS19250	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
KQ257_RS19260	COG4372	Transposase
KQ257_RS19305	COG1475	DNA binding
KQ257_RS19320	COG3853	Toxic anion resistance protein (TelA)
KQ257_RS19410	COG0484	heat shock protein binding
KQ257_RS19495	COG0741	lytic transglycosylase activity
KQ257_RS19530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
KQ257_RS19610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KQ257_RS19620	COG2826	transposase and inactivated derivatives, IS30 family
KQ257_RS19775	COG2826	transposase and inactivated derivatives, IS30 family