locus-tag	class	description
B7L41_RS00020	COG0741	lytic transglycosylase activity
B7L41_RS00055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L41_RS00135	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7L41_RS00205	COG1525	nuclease
B7L41_RS00250	COG1484	DNA-dependent DNA replication
B7L41_RS00255	COG2390	Transcriptional regulator
B7L41_RS00255	COG4584	PFAM Integrase catalytic
B7L41_RS00285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L41_RS00315	COG1475	DNA binding
B7L41_RS00440	COG0484	heat shock protein binding
B7L41_RS00510	COG2826	transposase and inactivated derivatives, IS30 family
B7L41_RS00520	COG2826	transposase and inactivated derivatives, IS30 family
B7L41_RS00590	COG0589	response to stress
B7L41_RS00595	COG0659	secondary active sulfate transmembrane transporter activity
B7L41_RS00610	COG1061	Type III restriction enzyme res subunit
B7L41_RS00645	COG0427	acetyl-CoA hydrolase
B7L41_RS00675	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7L41_RS00715	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7L41_RS00770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
B7L41_RS00780	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L41_RS00785	COG1733	regulation of RNA biosynthetic process
B7L41_RS00800	COG1733	regulation of RNA biosynthetic process
B7L41_RS00825	COG0667	Aldo Keto reductase
B7L41_RS00845	COG0583	DNA-binding transcription factor activity
B7L41_RS00850	COG2814	Major facilitator Superfamily
B7L41_RS00880	COG1335	isochorismatase
B7L41_RS00890	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS00895	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7L41_RS00905	COG1113	amino acid transport
B7L41_RS00915	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7L41_RS00930	COG2814	Major facilitator Superfamily
B7L41_RS00940	COG0351	phosphomethylpyrimidine kinase
B7L41_RS00940	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B7L41_RS00940	COG0352	thiamine-phosphate diphosphorylase activity
B7L41_RS00960	COG1309	transcriptional regulator
B7L41_RS00965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7L41_RS00970	COG3706	GGDEF domain
B7L41_RS00990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L41_RS01000	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7L41_RS01005	COG3162	membrane
B7L41_RS01010	COG2205	protein histidine kinase activity
B7L41_RS01010	COG2198	Histidine kinase
B7L41_RS01010	COG0784	Response regulator, receiver
B7L41_RS01035	COG1522	sequence-specific DNA binding
B7L41_RS01040	COG1335	isochorismatase
B7L41_RS01045	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7L41_RS01055	COG0668	transmembrane transport
B7L41_RS01060	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7L41_RS01065	COG1519	Transferase
B7L41_RS01070	COG1902	pentaerythritol trinitrate reductase activity
B7L41_RS01090	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B7L41_RS01115	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L41_RS01115	COG0426	domain, Protein
B7L41_RS01120	COG4774	siderophore transport
B7L41_RS01125	COG2119	membrane
B7L41_RS01135	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7L41_RS01145	COG4942	peptidase
B7L41_RS01160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B7L41_RS01170	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B7L41_RS01190	COG0189	ligase activity
B7L41_RS01210	COG0708	Exodeoxyribonuclease III
B7L41_RS01215	COG1393	Belongs to the ArsC family
B7L41_RS01230	COG3706	GGDEF domain
B7L41_RS01265	COG2351	hydroxyisourate hydrolase activity
B7L41_RS01270	COG2233	PERMEase
B7L41_RS01280	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L41_RS01290	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
B7L41_RS01300	COG3150	esterase
B7L41_RS01360	COG2918	glutathione biosynthetic process
B7L41_RS01375	COG2733	membrane
B7L41_RS01380	COG0436	Aminotransferase
B7L41_RS01385	COG0534	Mate efflux family protein
B7L41_RS01475	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B7L41_RS01480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B7L41_RS01490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7L41_RS01520	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7L41_RS01535	COG0010	Belongs to the arginase family
B7L41_RS01565	COG2188	Transcriptional regulator
B7L41_RS01575	COG0523	cobalamin synthesis protein
B7L41_RS01585	COG1113	amino acid transport
B7L41_RS01595	COG0625	glutathione transferase activity
B7L41_RS01615	COG1683	Conserved Protein
B7L41_RS01620	COG0534	Mate efflux family protein
B7L41_RS01625	COG0385	Bile acid
B7L41_RS01630	COG1335	isochorismatase
B7L41_RS01635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L41_RS01655	COG2116	formate transmembrane transporter activity
B7L41_RS01660	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7L41_RS01665	COG2133	pyrroloquinoline quinone binding
B7L41_RS01670	COG2983	Belongs to the UPF0260 family
B7L41_RS01690	COG1194	a g-specific adenine glycosylase
B7L41_RS01705	COG2818	Glycosylase
B7L41_RS01710	COG1064	alcohol dehydrogenase
B7L41_RS01715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L41_RS01730	COG0583	DNA-binding transcription factor activity
B7L41_RS01735	COG0656	L-ascorbic acid biosynthetic process
B7L41_RS01740	COG2814	Major facilitator Superfamily
B7L41_RS01775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L41_RS01790	COG2233	PERMEase
B7L41_RS01795	COG0583	DNA-binding transcription factor activity
B7L41_RS01820	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
B7L41_RS01830	COG0733	neurotransmitter:sodium symporter activity
B7L41_RS01870	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B7L41_RS01875	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B7L41_RS01880	COG0596	Alpha beta hydrolase
B7L41_RS01925	COG0488	(ABC) transporter
B7L41_RS01930	COG0586	Pfam SNARE associated Golgi protein
B7L41_RS01940	COG0187	DNA topoisomerase II activity
B7L41_RS01950	COG0592	DNA-directed DNA polymerase activity
B7L41_RS01975	COG0706	membrane insertase activity
B7L41_RS01990	COG1230	cation diffusion facilitator family transporter
B7L41_RS01995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L41_RS02010	COG0402	S-adenosylhomocysteine deaminase activity
B7L41_RS02020	COG0754	glutathionylspermidine amidase activity
B7L41_RS02030	COG0861	Integral membrane protein TerC family
B7L41_RS02035	COG0671	phosphoesterase, PA-phosphatase related
B7L41_RS02045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7L41_RS02065	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B7L41_RS02070	COG2951	lytic endotransglycosylase activity
B7L41_RS02100	COG0583	DNA-binding transcription factor activity
B7L41_RS02120	COG0657	acetylesterase activity
B7L41_RS02125	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7L41_RS02165	COG1047	Peptidyl-prolyl cis-trans
B7L41_RS02175	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B7L41_RS02180	COG0196	riboflavin kinase activity
B7L41_RS02190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7L41_RS02195	COG1309	transcriptional regulator
B7L41_RS02200	COG1116	anion transmembrane transporter activity
B7L41_RS02205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L41_RS02210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7L41_RS02215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L41_RS02220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L41_RS02240	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS02245	COG0546	phosphoglycolate phosphatase activity
B7L41_RS02295	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7L41_RS02300	COG0728	peptidoglycan biosynthetic process
B7L41_RS02330	COG1596	polysaccharide export
B7L41_RS02335	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B7L41_RS02340	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
B7L41_RS02345	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B7L41_RS02375	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B7L41_RS02380	COG0110	maltose O-acetyltransferase activity
B7L41_RS02390	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7L41_RS02405	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7L41_RS02410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7L41_RS02420	COG2186	Transcriptional regulator
B7L41_RS02430	COG0277	FAD linked oxidase domain protein
B7L41_RS02435	COG1448	Aminotransferase
B7L41_RS02440	COG1802	Transcriptional regulator
B7L41_RS02455	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7L41_RS02490	COG3328	transposase activity
B7L41_RS02510	COG1061	Type III restriction enzyme res subunit
B7L41_RS02535	COG0564	pseudouridine synthase activity
B7L41_RS02575	COG0251	oxidation-reduction process
B7L41_RS02580	COG1113	amino acid transport
B7L41_RS02585	COG1113	amino acid transport
B7L41_RS02605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7L41_RS02610	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS02615	COG1024	Enoyl-CoA hydratase
B7L41_RS02620	COG1024	Enoyl-CoA hydratase
B7L41_RS02625	COG0477	Major facilitator Superfamily
B7L41_RS02630	COG3916	Acyl-homoserine-lactone synthase
B7L41_RS02640	COG2197	response regulator
B7L41_RS02650	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS02655	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7L41_RS02655	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B7L41_RS02655	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B7L41_RS02655	COG3321	synthase
B7L41_RS02675	COG2267	carboxylic ester hydrolase activity
B7L41_RS02695	COG0271	Belongs to the BolA IbaG family
B7L41_RS02705	COG1192	Involved in chromosome partitioning
B7L41_RS02720	COG0586	Pfam SNARE associated Golgi protein
B7L41_RS02725	COG2259	Doxx family
B7L41_RS02730	COG4399	Belongs to the UPF0754 family
B7L41_RS02735	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7L41_RS02735	COG0519	Catalyzes the synthesis of GMP from XMP
B7L41_RS02780	COG0281	malic enzyme
B7L41_RS02785	COG2837	iron assimilation
B7L41_RS02790	COG1280	lysine exporter protein (LysE YggA)
B7L41_RS02795	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7L41_RS02800	COG1121	(ABC) transporter
B7L41_RS02865	COG0386	Belongs to the glutathione peroxidase family
B7L41_RS02880	COG1309	transcriptional regulator
B7L41_RS02885	COG0697	spore germination
B7L41_RS02895	COG0758	DNA mediated transformation
B7L41_RS02965	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7L41_RS02975	COG0655	NAD(P)H dehydrogenase (quinone) activity
B7L41_RS03010	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7L41_RS03020	COG2814	Major facilitator Superfamily
B7L41_RS03030	COG1253	flavin adenine dinucleotide binding
B7L41_RS03035	COG3012	SEC-C Motif Domain Protein
B7L41_RS03045	COG0477	Major facilitator Superfamily
B7L41_RS03055	COG0318	PFAM AMP-dependent synthetase and ligase
B7L41_RS03070	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B7L41_RS03085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L41_RS03095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L41_RS03100	COG0606	chelatase, subunit chli
B7L41_RS03130	COG2072	flavoprotein involved in K transport
B7L41_RS03135	COG0492	ferredoxin-NADP+ reductase activity
B7L41_RS03140	COG0431	NADPH-dependent FMN reductase
B7L41_RS03145	COG0798	PFAM Bile acid sodium symporter
B7L41_RS03155	COG0640	Transcriptional regulator
B7L41_RS03165	COG0589	response to stress
B7L41_RS03170	COG0789	Transcriptional regulator
B7L41_RS03200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B7L41_RS03265	COG0789	Transcriptional regulator
B7L41_RS03295	COG0659	secondary active sulfate transmembrane transporter activity
B7L41_RS03305	COG0606	chelatase, subunit chli
B7L41_RS03315	COG0347	Belongs to the P(II) protein family
B7L41_RS03320	COG0004	ammonium transporteR
B7L41_RS03330	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7L41_RS03330	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7L41_RS03370	COG0795	lipopolysaccharide-transporting ATPase activity
B7L41_RS03375	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B7L41_RS03380	COG0793	Belongs to the peptidase S41A family
B7L41_RS03395	COG2197	response regulator
B7L41_RS03405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7L41_RS03415	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L41_RS03420	COG4974	Belongs to the 'phage' integrase family
B7L41_RS03445	COG0772	Belongs to the SEDS family
B7L41_RS03450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7L41_RS03455	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7L41_RS03460	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7L41_RS03485	COG0697	spore germination
B7L41_RS03490	COG1538	Outer membrane efflux protein
B7L41_RS03510	COG3275	phosphorelay sensor kinase activity
B7L41_RS03520	COG0181	hydroxymethylbilane synthase activity
B7L41_RS03565	COG1716	ATPase activity
B7L41_RS03570	COG0546	phosphoglycolate phosphatase activity
B7L41_RS03670	COG2056	Na+-H+ antiporter family
B7L41_RS03685	COG0326	Molecular chaperone. Has ATPase activity
B7L41_RS03700	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7L41_RS03760	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7L41_RS03765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7L41_RS03765	COG2169	Transcriptional regulator
B7L41_RS03795	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B7L41_RS03805	COG0497	DNA recombination
B7L41_RS03820	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7L41_RS03830	COG0237	dephospho-CoA kinase activity
B7L41_RS03880	COG0195	Participates in both transcription termination and antitermination
B7L41_RS03895	COG1320	monovalent cation:proton antiporter activity
B7L41_RS03900	COG2212	antiporter activity
B7L41_RS03905	COG1863	multisubunit Na H antiporter MnhE subunit
B7L41_RS03910	COG0651	ATP synthesis coupled electron transport
B7L41_RS03915	COG1006	Multisubunit Na H antiporter MnhC subunit
B7L41_RS03920	COG2111	Na H antiporter
B7L41_RS03920	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7L41_RS03935	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B7L41_RS03940	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L41_RS03955	COG2226	methyltransferase
B7L41_RS03975	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B7L41_RS03980	COG1074	ATP-dependent DNA helicase activity
B7L41_RS03985	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7L41_RS03990	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7L41_RS04005	COG0598	Magnesium transport protein CorA
B7L41_RS04010	COG0789	Transcriptional regulator
B7L41_RS04015	COG0484	heat shock protein binding
B7L41_RS04030	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7L41_RS04030	COG0475	glutathione-regulated potassium exporter activity
B7L41_RS04035	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7L41_RS04055	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7L41_RS04065	COG4535	Mg2 and Co2 transporter CorC
B7L41_RS04070	COG0425	Belongs to the sulfur carrier protein TusA family
B7L41_RS04080	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B7L41_RS04080	COG0644	oxidoreductase
B7L41_RS04090	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7L41_RS04105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L41_RS04110	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B7L41_RS04120	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7L41_RS04120	COG0493	'glutamate synthase
B7L41_RS04145	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B7L41_RS04160	COG0534	Mate efflux family protein
B7L41_RS04170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7L41_RS04175	COG4221	oxidoreductase activity
B7L41_RS04180	COG0583	DNA-binding transcription factor activity
B7L41_RS04195	COG0318	PFAM AMP-dependent synthetase and ligase
B7L41_RS04200	COG1530	ribonuclease E activity
B7L41_RS04215	COG0546	phosphoglycolate phosphatase activity
B7L41_RS04220	COG2378	regulation of single-species biofilm formation
B7L41_RS04225	COG0625	glutathione transferase activity
B7L41_RS04235	COG0583	DNA-binding transcription factor activity
B7L41_RS04290	COG0473	3-isopropylmalate dehydrogenase activity
B7L41_RS04345	COG1301	dicarboxylic acid transport
B7L41_RS04355	COG1560	Kdo2-lipid A biosynthetic process
B7L41_RS04360	COG1280	lysine exporter protein (LysE YggA)
B7L41_RS04365	COG0488	(ABC) transporter
B7L41_RS04370	COG2900	Belongs to the SlyX family
B7L41_RS04380	COG1733	regulation of RNA biosynthetic process
B7L41_RS04405	COG0210	DNA helicase
B7L41_RS04410	COG0724	RNA recognition motif
B7L41_RS04430	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7L41_RS04430	COG4651	solute:proton antiporter activity
B7L41_RS04455	COG0788	formyltetrahydrofolate deformylase activity
B7L41_RS04555	COG2813	Specifically methylates the guanine in position
B7L41_RS04555	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7L41_RS04565	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7L41_RS04575	COG4774	siderophore transport
B7L41_RS04585	COG0740	serine-type endopeptidase activity
B7L41_RS04605	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7L41_RS04605	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B7L41_RS04610	COG0857	belongs to the CobB CobQ family
B7L41_RS04610	COG0280	phosphate acetyltransferase
B7L41_RS04615	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7L41_RS04625	COG0800	Aldolase
B7L41_RS04635	COG3265	gluconokinase activity
B7L41_RS04640	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS04650	COG2267	carboxylic ester hydrolase activity
B7L41_RS04665	COG0793	Belongs to the peptidase S41A family
B7L41_RS04700	COG1426	Protein conserved in bacteria
B7L41_RS04740	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7L41_RS04750	COG1162	GTPase activity
B7L41_RS04755	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B7L41_RS04770	COG1538	Outer membrane efflux protein
B7L41_RS04775	COG0577	efflux transmembrane transporter activity
B7L41_RS04775	COG1136	(ABC) transporter
B7L41_RS04780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L41_RS04810	COG0028	Belongs to the TPP enzyme family
B7L41_RS04815	COG0440	acetolactate synthase activity
B7L41_RS04865	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B7L41_RS04880	COG0084	hydrolase, TatD family'
B7L41_RS04890	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B7L41_RS04895	COG0583	DNA-binding transcription factor activity
B7L41_RS04905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7L41_RS04995	COG2205	protein histidine kinase activity
B7L41_RS05010	COG2132	Multicopper oxidase
B7L41_RS05030	COG2814	Major facilitator Superfamily
B7L41_RS05040	COG0697	spore germination
B7L41_RS05070	COG3622	Belongs to the hyi family
B7L41_RS05075	COG2084	Dehydrogenase
B7L41_RS05080	COG1024	Enoyl-CoA hydratase
B7L41_RS05085	COG5002	protein histidine kinase activity
B7L41_RS05085	COG0784	Response regulator, receiver
B7L41_RS05085	COG2205	protein histidine kinase activity
B7L41_RS05105	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7L41_RS05115	COG3956	TIGRFAM MazG family protein
B7L41_RS05120	COG1555	photosystem II stabilization
B7L41_RS05125	COG0617	tRNA 3'-terminal CCA addition
B7L41_RS05130	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B7L41_RS05150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7L41_RS05155	COG3028	Belongs to the UPF0307 family
B7L41_RS05160	COG0318	PFAM AMP-dependent synthetase and ligase
B7L41_RS05180	COG0625	glutathione transferase activity
B7L41_RS05185	COG1238	metal cluster binding
B7L41_RS05225	COG0072	phenylalanine-tRNA ligase activity
B7L41_RS05250	COG0248	Ppx GppA phosphatase
B7L41_RS05260	COG0037	tRNA processing
B7L41_RS05300	COG1764	response to oxidative stress
B7L41_RS05305	COG1846	Transcriptional regulator
B7L41_RS05315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7L41_RS05375	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7L41_RS05380	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B7L41_RS05385	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B7L41_RS05395	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7L41_RS05445	COG1214	PFAM Peptidase M22, glycoprotease
B7L41_RS05460	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B7L41_RS05470	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7L41_RS05475	COG0561	phosphatase activity
B7L41_RS05485	COG2132	Multicopper oxidase
B7L41_RS05490	COG3667	copper resistance
B7L41_RS05505	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7L41_RS05510	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B7L41_RS05515	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B7L41_RS05545	COG1063	alcohol dehydrogenase
B7L41_RS05550	COG0583	DNA-binding transcription factor activity
B7L41_RS05555	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS05560	COG2814	Major facilitator Superfamily
B7L41_RS05565	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7L41_RS05575	COG1053	succinate dehydrogenase
B7L41_RS05580	COG0583	DNA-binding transcription factor activity
B7L41_RS05600	COG0583	DNA-binding transcription factor activity
B7L41_RS05630	COG0583	DNA-binding transcription factor activity
B7L41_RS05645	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L41_RS05655	COG1309	transcriptional regulator
B7L41_RS05685	COG0384	phenazine biosynthesis protein PhzF
B7L41_RS05695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7L41_RS05715	COG0745	RESPONSE REGULATOR receiver
B7L41_RS05755	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B7L41_RS05785	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7L41_RS05790	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7L41_RS05815	COG0583	DNA-binding transcription factor activity
B7L41_RS05835	COG0668	transmembrane transport
B7L41_RS05840	COG2081	HI0933 family
B7L41_RS05845	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B7L41_RS05875	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7L41_RS05875	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7L41_RS05885	COG0489	protein tyrosine kinase activity
B7L41_RS05945	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7L41_RS05955	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B7L41_RS05970	COG0730	response to heat
B7L41_RS05980	COG1196	nuclear chromosome segregation
B7L41_RS06000	COG2223	nitrite transmembrane transporter activity
B7L41_RS06005	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
B7L41_RS06010	COG1877	trehalose-phosphatase activity
B7L41_RS06015	COG0596	Alpha beta hydrolase
B7L41_RS06015	COG2226	methyltransferase
B7L41_RS06015	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7L41_RS06030	COG4106	trans-aconitate 2-methyltransferase activity
B7L41_RS06045	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B7L41_RS06050	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B7L41_RS06055	COG0009	L-threonylcarbamoyladenylate synthase
B7L41_RS06060	COG3101	peptidyl-lysine hydroxylation
B7L41_RS06065	COG1399	metal-binding, possibly nucleic acid-binding protein
B7L41_RS06090	COG1652	LysM domain
B7L41_RS06095	COG0351	phosphomethylpyrimidine kinase
B7L41_RS06095	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B7L41_RS06095	COG0352	thiamine-phosphate diphosphorylase activity
B7L41_RS06105	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7L41_RS06135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7L41_RS06165	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B7L41_RS06180	COG0358	DNA primase activity
B7L41_RS06190	COG0564	pseudouridine synthase activity
B7L41_RS06215	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7L41_RS06235	COG0583	DNA-binding transcription factor activity
B7L41_RS06240	COG0473	3-isopropylmalate dehydrogenase activity
B7L41_RS06250	COG0657	acetylesterase activity
B7L41_RS06260	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS06280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7L41_RS06280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B7L41_RS06295	COG1981	membrane
B7L41_RS06340	COG0456	acetyltransferase
B7L41_RS06350	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B7L41_RS06355	COG0492	ferredoxin-NADP+ reductase activity
B7L41_RS06360	COG1674	ftsk spoiiie
B7L41_RS06360	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B7L41_RS06365	COG1280	lysine exporter protein (LysE YggA)
B7L41_RS06380	COG2894	cell division
B7L41_RS06395	COG0204	Acyl-transferase
B7L41_RS06400	COG2885	chlorophyll binding
B7L41_RS06405	COG0210	DNA helicase
B7L41_RS06415	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7L41_RS06430	COG0121	glutamine amidotransferase
B7L41_RS06455	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7L41_RS06460	COG0735	belongs to the Fur family
B7L41_RS06485	COG0420	3'-5' exonuclease activity
B7L41_RS06505	COG1090	epimerase
B7L41_RS06520	COG2050	protein possibly involved in aromatic compounds catabolism
B7L41_RS06530	COG2814	Major facilitator Superfamily
B7L41_RS06535	COG0405	Gamma-glutamyltransferase
B7L41_RS06545	COG0582	viral genome integration into host DNA
B7L41_RS06635	COG0084	hydrolase, TatD family'
B7L41_RS06660	COG0477	Major facilitator Superfamily
B7L41_RS06665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L41_RS06675	COG1595	DNA-templated transcription, initiation
B7L41_RS06730	COG0531	amino acid
B7L41_RS06735	COG2040	homocysteine
B7L41_RS06760	COG1309	transcriptional regulator
B7L41_RS06765	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L41_RS06770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L41_RS06780	COG1607	acyl-coa hydrolase
B7L41_RS06790	COG0523	cobalamin synthesis protein
B7L41_RS06800	COG4681	YaeQ
B7L41_RS06810	COG0726	polysaccharide deacetylase
B7L41_RS06810	COG1649	PFAM Uncharacterised BCR, COG1649
B7L41_RS06815	COG1215	transferase activity, transferring glycosyl groups
B7L41_RS06825	COG1024	Enoyl-CoA hydratase
B7L41_RS06840	COG1414	Transcriptional regulator
B7L41_RS06860	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS06870	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L41_RS06875	COG2271	Major facilitator Superfamily
B7L41_RS06885	COG2267	carboxylic ester hydrolase activity
B7L41_RS06890	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS06905	COG0028	Belongs to the TPP enzyme family
B7L41_RS06915	COG0477	Major facilitator Superfamily
B7L41_RS06920	COG0242	peptide deformylase activity
B7L41_RS06925	COG2066	Belongs to the glutaminase family
B7L41_RS06930	COG2207	Transcriptional regulator
B7L41_RS06935	COG2223	nitrite transmembrane transporter activity
B7L41_RS06955	COG0583	DNA-binding transcription factor activity
B7L41_RS06960	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS06965	COG2271	Major facilitator Superfamily
B7L41_RS06970	COG3959	Transketolase, thiamine diphosphate binding domain
B7L41_RS06975	COG3958	Transketolase
B7L41_RS06985	COG0306	phosphate transporter
B7L41_RS07000	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B7L41_RS07055	COG4181	ATPase activity
B7L41_RS07060	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B7L41_RS07085	COG0583	DNA-binding transcription factor activity
B7L41_RS07095	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L41_RS07100	COG1773	rubredoxin
B7L41_RS07145	COG2851	Citrate transporter
B7L41_RS07155	COG1253	flavin adenine dinucleotide binding
B7L41_RS07195	COG0804	urea catabolic process
B7L41_RS07205	COG0830	nickel cation binding
B7L41_RS07220	COG0742	ribosomal rna small subunit methyltransferase
B7L41_RS07225	COG0768	penicillin binding
B7L41_RS07245	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7L41_RS07250	COG2878	Part of a membrane complex involved in electron transport
B7L41_RS07255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7L41_RS07265	COG3384	dioxygenase
B7L41_RS07280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B7L41_RS07315	COG0006	proline dipeptidase activity
B7L41_RS07320	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L41_RS07325	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L41_RS07345	COG1279	arginine transmembrane transporter activity
B7L41_RS07350	COG0583	DNA-binding transcription factor activity
B7L41_RS07390	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L41_RS07395	COG0741	lytic transglycosylase activity
B7L41_RS07395	COG1388	LysM domain
B7L41_RS07395	COG1388	LysM domain
B7L41_RS07395	COG0741	lytic transglycosylase activity
B7L41_RS07405	COG4174	ABC transporter (Permease)
B7L41_RS07410	COG4239	(ABC) transporter, permease
B7L41_RS07415	COG4172	Belongs to the ABC transporter superfamily
B7L41_RS07470	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L41_RS07480	COG5001	Diguanylate cyclase
B7L41_RS07480	COG2203	Gaf domain
B7L41_RS07480	COG3706	GGDEF domain
B7L41_RS07480	COG4251	negative regulation of phosphorylation
B7L41_RS07490	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L41_RS07490	COG1902	pentaerythritol trinitrate reductase activity
B7L41_RS07530	COG3209	COG3209 Rhs family protein
B7L41_RS07570	COG1113	amino acid transport
B7L41_RS07580	COG0531	amino acid
B7L41_RS07600	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS07620	COG1113	amino acid transport
B7L41_RS07650	COG0697	spore germination
B7L41_RS07655	COG2721	sulfolactate sulfo-lyase activity
B7L41_RS07660	COG2271	Major facilitator Superfamily
B7L41_RS07665	COG4948	Mandelate Racemase Muconate Lactonizing
B7L41_RS07675	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS07680	COG2186	Transcriptional regulator
B7L41_RS07705	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS07715	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS07720	COG1024	Enoyl-CoA hydratase
B7L41_RS07725	COG2814	Major facilitator Superfamily
B7L41_RS07740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L41_RS07785	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
B7L41_RS07790	COG2072	flavoprotein involved in K transport
B7L41_RS07795	COG0300	oxidoreductase activity
B7L41_RS07805	COG1309	transcriptional regulator
B7L41_RS07810	COG1741	Belongs to the pirin family
B7L41_RS07825	COG2072	flavoprotein involved in K transport
B7L41_RS07835	COG2252	PERMEase
B7L41_RS07840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7L41_RS07845	COG3038	cytochrome b561
B7L41_RS07855	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7L41_RS07865	COG0527	aspartate kinase activity
B7L41_RS07875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7L41_RS07885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B7L41_RS07900	COG0667	Aldo Keto reductase
B7L41_RS07910	COG1765	OsmC-like protein
B7L41_RS07925	COG0542	response to heat
B7L41_RS07960	COG2885	chlorophyll binding
B7L41_RS07970	COG0625	glutathione transferase activity
B7L41_RS07975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B7L41_RS07995	COG3634	alkyl hydroperoxide reductase activity
B7L41_RS08005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7L41_RS08015	COG0450	alkyl hydroperoxide reductase
B7L41_RS08020	COG1643	Atp-dependent helicase
B7L41_RS08035	COG2814	Major facilitator Superfamily
B7L41_RS08040	COG3135	benzoate transporter
B7L41_RS08045	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS08050	COG0543	2 iron, 2 sulfur cluster binding
B7L41_RS08050	COG0633	Ferredoxin
B7L41_RS08055	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B7L41_RS08060	COG4638	Rieske (2fe-2S)
B7L41_RS08065	COG0583	DNA-binding transcription factor activity
B7L41_RS08120	COG1570	exodeoxyribonuclease VII activity
B7L41_RS08155	COG1280	lysine exporter protein (LysE YggA)
B7L41_RS08160	COG1278	Cold shock
B7L41_RS08195	COG2814	Major facilitator Superfamily
B7L41_RS08275	COG5410	chromosome segregation
B7L41_RS08280	COG3567	Phage-associated protein, HI1409 family
B7L41_RS08300	COG3566	protein conserved in bacteria
B7L41_RS08320	COG5434	Belongs to the glycosyl hydrolase 28 family
B7L41_RS08380	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B7L41_RS08390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B7L41_RS08395	COG1137	ATPase activity
B7L41_RS08400	COG1538	Outer membrane efflux protein
B7L41_RS08430	COG4122	O-methyltransferase activity
B7L41_RS08440	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B7L41_RS08455	COG1522	sequence-specific DNA binding
B7L41_RS08460	COG5006	permease, DMT superfamily
B7L41_RS08470	COG1560	Kdo2-lipid A biosynthetic process
B7L41_RS08495	COG2814	Major facilitator Superfamily
B7L41_RS08515	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7L41_RS08570	COG3209	COG3209 Rhs family protein
B7L41_RS08590	COG0583	DNA-binding transcription factor activity
B7L41_RS08595	COG1914	H( )-stimulated, divalent metal cation uptake system
B7L41_RS08615	COG4770	biotin carboxylase activity
B7L41_RS08620	COG0038	chloride channel
B7L41_RS08650	COG1309	transcriptional regulator
B7L41_RS08660	COG1063	alcohol dehydrogenase
B7L41_RS08675	COG0439	Biotin carboxylase
B7L41_RS08680	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L41_RS08685	COG1733	regulation of RNA biosynthetic process
B7L41_RS08695	COG0864	Transcriptional regulator
B7L41_RS08705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7L41_RS08710	COG1116	anion transmembrane transporter activity
B7L41_RS08830	COG0590	tRNA wobble adenosine to inosine editing
B7L41_RS08835	COG2807	transmembrane transport
B7L41_RS08855	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B7L41_RS08865	COG0789	Transcriptional regulator
B7L41_RS08880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L41_RS08900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7L41_RS08935	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS08940	COG0531	amino acid
B7L41_RS08945	COG1760	l-serine dehydratase
B7L41_RS08950	COG2030	dehydratase
B7L41_RS08950	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS08955	COG3396	Phenylacetate-CoA oxygenase
B7L41_RS08960	COG3460	Phenylacetate-CoA oxygenase
B7L41_RS08965	COG3396	Phenylacetate-CoA oxygenase
B7L41_RS08970	COG2151	metal-sulfur cluster biosynthetic enzyme
B7L41_RS08975	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L41_RS08980	COG1024	Enoyl-CoA hydratase
B7L41_RS08985	COG1024	Enoyl-CoA hydratase
B7L41_RS08990	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7L41_RS08995	COG0183	Belongs to the thiolase family
B7L41_RS09000	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
B7L41_RS09005	COG3327	negative regulation of DNA-templated transcription, initiation
B7L41_RS09015	COG2050	protein possibly involved in aromatic compounds catabolism
B7L41_RS09020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
B7L41_RS09025	COG0210	DNA helicase
B7L41_RS09065	COG1278	Cold shock
B7L41_RS09090	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7L41_RS09095	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7L41_RS09100	COG2271	Major facilitator Superfamily
B7L41_RS09105	COG0753	catalase activity
B7L41_RS09110	COG3038	cytochrome b561
B7L41_RS09130	COG2267	carboxylic ester hydrolase activity
B7L41_RS09135	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L41_RS09140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7L41_RS09145	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS09150	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B7L41_RS09160	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS09165	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7L41_RS09170	COG0583	DNA-binding transcription factor activity
B7L41_RS09180	COG1414	Transcriptional regulator
B7L41_RS09185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L41_RS09195	COG1840	ABC-type Fe3 transport system, periplasmic component
B7L41_RS09200	COG3842	ATPase activity
B7L41_RS09215	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B7L41_RS09220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7L41_RS09225	COG2814	Major facilitator Superfamily
B7L41_RS09230	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS09235	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7L41_RS09245	COG1024	Enoyl-CoA hydratase
B7L41_RS09255	COG2814	Major facilitator Superfamily
B7L41_RS09265	COG0183	Belongs to the thiolase family
B7L41_RS09270	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7L41_RS09275	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS09280	COG1024	Enoyl-CoA hydratase
B7L41_RS09285	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS09290	COG2814	Major facilitator Superfamily
B7L41_RS09295	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7L41_RS09300	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L41_RS09310	COG2814	Major facilitator Superfamily
B7L41_RS09320	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS09335	COG0583	DNA-binding transcription factor activity
B7L41_RS09345	COG4770	biotin carboxylase activity
B7L41_RS09350	COG1024	Enoyl-CoA hydratase
B7L41_RS09355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7L41_RS09360	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS09365	COG1309	transcriptional regulator
B7L41_RS09370	COG0318	PFAM AMP-dependent synthetase and ligase
B7L41_RS09390	COG0583	DNA-binding transcription factor activity
B7L41_RS09440	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS09495	COG0765	amino acid transport
B7L41_RS09500	COG0765	amino acid transport
B7L41_RS09505	COG1126	abc transporter atp-binding protein
B7L41_RS09515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7L41_RS09525	COG1280	lysine exporter protein (LysE YggA)
B7L41_RS09530	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7L41_RS09535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7L41_RS09540	COG1045	serine acetyltransferase
B7L41_RS09555	COG0583	DNA-binding transcription factor activity
B7L41_RS09560	COG0625	glutathione transferase activity
B7L41_RS09565	COG0625	glutathione transferase activity
B7L41_RS09570	COG0583	DNA-binding transcription factor activity
B7L41_RS09580	COG1346	cytolysis
B7L41_RS09585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L41_RS09600	COG2814	Major facilitator Superfamily
B7L41_RS09610	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
B7L41_RS09615	COG3052	prosthetic group binding
B7L41_RS09635	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B7L41_RS09655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L41_RS09660	COG1294	oxidase, subunit
B7L41_RS09665	COG1271	oxidase subunit
B7L41_RS09690	COG0477	Major facilitator Superfamily
B7L41_RS09700	COG4521	taurine ABC transporter
B7L41_RS09705	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B7L41_RS09710	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L41_RS09715	COG2175	clavaminate synthase activity
B7L41_RS09725	COG1953	Uracil, thiamine, allantoin
B7L41_RS09735	COG0583	DNA-binding transcription factor activity
B7L41_RS09745	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B7L41_RS09760	COG0640	Transcriptional regulator
B7L41_RS09765	COG0798	PFAM Bile acid sodium symporter
B7L41_RS09770	COG0583	DNA-binding transcription factor activity
B7L41_RS09785	COG3634	alkyl hydroperoxide reductase activity
B7L41_RS09820	COG1301	dicarboxylic acid transport
B7L41_RS09830	COG0436	Aminotransferase
B7L41_RS09840	COG0386	Belongs to the glutathione peroxidase family
B7L41_RS09880	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7L41_RS09905	COG0012	GTP binding
B7L41_RS09910	COG2011	ABC-type metal ion transport system permease component
B7L41_RS09915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7L41_RS09925	COG1464	Belongs to the NlpA lipoprotein family
B7L41_RS09955	COG0765	amino acid transport
B7L41_RS09960	COG0765	amino acid transport
B7L41_RS09965	COG1126	abc transporter atp-binding protein
B7L41_RS09975	COG1522	sequence-specific DNA binding
B7L41_RS09990	COG1309	transcriptional regulator
B7L41_RS10010	COG0583	DNA-binding transcription factor activity
B7L41_RS10020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B7L41_RS10030	COG0697	spore germination
B7L41_RS10060	COG3121	Chaperone
B7L41_RS10065	COG3539	Fimbrial protein
B7L41_RS10090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B7L41_RS10090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B7L41_RS10135	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7L41_RS10145	COG2353	YceI-like domain
B7L41_RS10155	COG3698	Phosphodiester glycosidase
B7L41_RS10170	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B7L41_RS10175	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7L41_RS10175	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7L41_RS10175	COG0506	proline dehydrogenase activity
B7L41_RS10185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7L41_RS10190	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B7L41_RS10210	COG1132	(ABC) transporter
B7L41_RS10215	COG3122	Protein conserved in bacteria
B7L41_RS10220	COG3619	membrane
B7L41_RS10235	COG0640	Transcriptional regulator
B7L41_RS10245	COG2850	peptidyl-arginine hydroxylation
B7L41_RS10250	COG0424	maF-like protein
B7L41_RS10270	COG0191	fructose-bisphosphate aldolase activity
B7L41_RS10275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7L41_RS10290	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7L41_RS10300	COG1192	Involved in chromosome partitioning
B7L41_RS10305	COG1475	DNA binding
B7L41_RS10310	COG0811	peptide transport
B7L41_RS10320	COG1132	(ABC) transporter
B7L41_RS10325	COG1663	tetraacyldisaccharide 4'-kinase activity
B7L41_RS10345	COG0084	hydrolase, TatD family'
B7L41_RS10410	COG0776	regulation of translation
B7L41_RS10440	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B7L41_RS10445	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B7L41_RS10470	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
B7L41_RS10490	COG0339	signal peptide processing
B7L41_RS10500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7L41_RS10535	COG0702	epimerase
B7L41_RS10540	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B7L41_RS10560	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B7L41_RS10590	COG0316	Belongs to the HesB IscA family
B7L41_RS10595	COG0822	iron-sulfur transferase activity
B7L41_RS10620	COG0776	regulation of translation
B7L41_RS10625	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7L41_RS10630	COG2207	Transcriptional regulator
B7L41_RS10635	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7L41_RS10640	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS10645	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS10660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7L41_RS10675	COG2814	Major facilitator Superfamily
B7L41_RS10680	COG4264	IucA IucC family
B7L41_RS10685	COG4264	IucA IucC family
B7L41_RS10695	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B7L41_RS10725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7L41_RS10740	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B7L41_RS10745	COG0406	alpha-ribazole phosphatase activity
B7L41_RS10760	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7L41_RS10765	COG0730	response to heat
B7L41_RS10785	COG4773	Receptor
B7L41_RS10790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7L41_RS10845	COG2226	methyltransferase
B7L41_RS10870	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B7L41_RS10900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7L41_RS10910	COG0133	tryptophan synthase activity
B7L41_RS10925	COG3706	GGDEF domain
B7L41_RS10940	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7L41_RS10945	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7L41_RS10950	COG0022	dehydrogenase e1 component
B7L41_RS10955	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7L41_RS10960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7L41_RS10970	COG1063	alcohol dehydrogenase
B7L41_RS10975	COG3781	membrane
B7L41_RS10985	COG3453	Protein conserved in bacteria
B7L41_RS10985	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L41_RS10995	COG0730	response to heat
B7L41_RS11010	COG2207	Transcriptional regulator
B7L41_RS11010	COG3708	Transcriptional regulator
B7L41_RS11015	COG1733	regulation of RNA biosynthetic process
B7L41_RS11020	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B7L41_RS11030	COG2188	Transcriptional regulator
B7L41_RS11045	COG4521	taurine ABC transporter
B7L41_RS11050	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L41_RS11070	COG0477	Major facilitator Superfamily
B7L41_RS11080	COG1027	Aspartate ammonia-lyase
B7L41_RS11095	COG0583	DNA-binding transcription factor activity
B7L41_RS11100	COG0583	DNA-binding transcription factor activity
B7L41_RS11105	COG0183	Belongs to the thiolase family
B7L41_RS11110	COG2031	fatty acid transporter
B7L41_RS11125	COG0583	DNA-binding transcription factor activity
B7L41_RS11135	COG2610	gluconate transmembrane transporter activity
B7L41_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS11145	COG2207	Transcriptional regulator
B7L41_RS11160	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS11170	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L41_RS11185	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L41_RS11185	COG0543	2 iron, 2 sulfur cluster binding
B7L41_RS11190	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B7L41_RS11195	COG4638	Rieske (2fe-2S)
B7L41_RS11205	COG0725	ABC transporter, periplasmic molybdate-binding protein
B7L41_RS11210	COG4149	molybdate abc transporter
B7L41_RS11215	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B7L41_RS11220	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS11225	COG3433	isochorismatase activity
B7L41_RS11225	COG1535	isochorismatase
B7L41_RS11285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7L41_RS11300	COG0753	catalase activity
B7L41_RS11310	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B7L41_RS11425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7L41_RS11435	COG2072	flavoprotein involved in K transport
B7L41_RS11445	COG1538	Outer membrane efflux protein
B7L41_RS11450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7L41_RS11455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L41_RS11460	COG0745	RESPONSE REGULATOR receiver
B7L41_RS11465	COG2205	protein histidine kinase activity
B7L41_RS11475	COG2207	Transcriptional regulator
B7L41_RS11490	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS11500	COG1073	alpha beta
B7L41_RS11535	COG0556	nucleotide-excision repair
B7L41_RS11550	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B7L41_RS11610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7L41_RS11620	COG2084	Dehydrogenase
B7L41_RS11630	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7L41_RS11635	COG0583	DNA-binding transcription factor activity
B7L41_RS11645	COG0129	dihydroxy-acid dehydratase activity
B7L41_RS11650	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS11665	COG1566	PFAM secretion protein HlyD family protein
B7L41_RS11680	COG0583	DNA-binding transcription factor activity
B7L41_RS11695	COG2188	Transcriptional regulator
B7L41_RS11770	COG1473	amidohydrolase
B7L41_RS11780	COG0475	glutathione-regulated potassium exporter activity
B7L41_RS11780	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7L41_RS11795	COG0583	DNA-binding transcription factor activity
B7L41_RS11800	COG1335	isochorismatase
B7L41_RS11820	COG1902	pentaerythritol trinitrate reductase activity
B7L41_RS11830	COG4689	acetoacetate decarboxylase
B7L41_RS11835	COG4221	oxidoreductase activity
B7L41_RS11855	COG1309	transcriptional regulator
B7L41_RS11895	COG1902	pentaerythritol trinitrate reductase activity
B7L41_RS11895	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L41_RS11910	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS11930	COG2186	Transcriptional regulator
B7L41_RS11940	COG0583	DNA-binding transcription factor activity
B7L41_RS11945	COG4948	Mandelate Racemase Muconate Lactonizing
B7L41_RS11950	COG4829	muconolactone delta-isomerase
B7L41_RS11960	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7L41_RS11965	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L41_RS11970	COG0183	Belongs to the thiolase family
B7L41_RS11975	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7L41_RS11985	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS11995	COG3733	amine oxidase
B7L41_RS12005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L41_RS12015	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS12025	COG4638	Rieske (2fe-2S)
B7L41_RS12045	COG0154	amidase activity
B7L41_RS12055	COG2814	Major facilitator Superfamily
B7L41_RS12080	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS12085	COG0583	DNA-binding transcription factor activity
B7L41_RS12090	COG1414	Transcriptional regulator
B7L41_RS12105	COG2391	methyltransferase activity
B7L41_RS12115	COG4993	Dehydrogenase
B7L41_RS12120	COG3659	wide pore channel activity
B7L41_RS12125	COG3420	alginic acid biosynthetic process
B7L41_RS12130	COG0710	3-dehydroquinate dehydratase activity
B7L41_RS12135	COG3485	protocatechuate 3,4-dioxygenase
B7L41_RS12140	COG3485	protocatechuate 3,4-dioxygenase
B7L41_RS12145	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7L41_RS12150	COG2271	Major facilitator Superfamily
B7L41_RS12155	COG0596	Alpha beta hydrolase
B7L41_RS12160	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7L41_RS12165	COG0183	Belongs to the thiolase family
B7L41_RS12170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L41_RS12175	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7L41_RS12185	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B7L41_RS12190	COG2323	membrane
B7L41_RS12235	COG1902	pentaerythritol trinitrate reductase activity
B7L41_RS12235	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L41_RS12260	COG0542	response to heat
B7L41_RS12265	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B7L41_RS12295	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7L41_RS12300	COG0569	domain protein
B7L41_RS12305	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7L41_RS12320	COG4774	siderophore transport
B7L41_RS12325	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7L41_RS12335	COG1585	Membrane protein implicated in regulation of membrane protease activity
B7L41_RS12355	COG1294	oxidase, subunit
B7L41_RS12360	COG4890	Cyd operon protein YbgT
B7L41_RS12370	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
B7L41_RS12380	COG0552	protein localization to endoplasmic reticulum
B7L41_RS12405	COG0517	IMP dehydrogenase activity
B7L41_RS12405	COG0516	GMP reductase activity
B7L41_RS12410	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7L41_RS12415	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B7L41_RS12425	COG0583	DNA-binding transcription factor activity
B7L41_RS12430	COG0024	Methionine aminopeptidase
B7L41_RS12460	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7L41_RS12460	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7L41_RS12465	COG1105	Belongs to the carbohydrate kinase PfkB family
B7L41_RS12470	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B7L41_RS12470	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7L41_RS12470	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7L41_RS12495	COG3300	MHYT domain
B7L41_RS12495	COG5001	Diguanylate cyclase
B7L41_RS12510	COG2135	peptidase activity
B7L41_RS12515	COG0659	secondary active sulfate transmembrane transporter activity
B7L41_RS12530	COG1113	amino acid transport
B7L41_RS12540	COG1522	sequence-specific DNA binding
B7L41_RS12565	COG1011	Hydrolase
B7L41_RS12570	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B7L41_RS12580	COG2137	regulation of response to DNA damage stimulus
B7L41_RS12595	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7L41_RS12630	COG0575	Belongs to the CDS family
B7L41_RS12635	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7L41_RS12655	COG3852	Histidine kinase
B7L41_RS12660	COG2204	response regulator
B7L41_RS12720	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7L41_RS12725	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B7L41_RS12745	COG0697	spore germination
B7L41_RS12760	COG0303	'Molybdopterin
B7L41_RS12765	COG0315	cyclic pyranopterin monophosphate synthase activity
B7L41_RS12765	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7L41_RS12780	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7L41_RS12785	COG0243	molybdopterin cofactor binding
B7L41_RS12795	COG0243	molybdopterin cofactor binding
B7L41_RS12800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L41_RS12805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L41_RS12805	COG2146	nitrite reductase [NAD(P)H] activity
B7L41_RS12815	COG0745	RESPONSE REGULATOR receiver
B7L41_RS12820	COG1116	anion transmembrane transporter activity
B7L41_RS12820	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L41_RS12835	COG0511	ligase activity, forming carbon-carbon bonds
B7L41_RS12850	COG2814	Major facilitator Superfamily
B7L41_RS12880	COG0069	glutamate synthase activity
B7L41_RS12900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7L41_RS12910	COG1454	alcohol dehydrogenase
B7L41_RS12915	COG0824	Thioesterase
B7L41_RS12925	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7L41_RS12940	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7L41_RS12945	COG2030	dehydratase
B7L41_RS12955	COG0183	Belongs to the thiolase family
B7L41_RS12965	COG0583	DNA-binding transcription factor activity
B7L41_RS12970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7L41_RS12980	COG1522	sequence-specific DNA binding
B7L41_RS12985	COG3135	benzoate transporter
B7L41_RS12995	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7L41_RS13010	COG0589	response to stress
B7L41_RS13015	COG0488	(ABC) transporter
B7L41_RS13030	COG4773	Receptor
B7L41_RS13060	COG0668	transmembrane transport
B7L41_RS13070	COG1309	transcriptional regulator
B7L41_RS13090	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
B7L41_RS13120	COG1605	Chorismate mutase
B7L41_RS13160	COG0308	aminopeptidase N
B7L41_RS13185	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7L41_RS13190	COG1454	alcohol dehydrogenase
B7L41_RS13210	COG0531	amino acid
B7L41_RS13215	COG4303	Ethanolamine ammonia lyase large subunit
B7L41_RS13220	COG4302	ethanolamine ammonia-lyase activity
B7L41_RS13225	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7L41_RS13225	COG0519	Catalyzes the synthesis of GMP from XMP
B7L41_RS13230	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7L41_RS13255	COG0697	spore germination
B7L41_RS13260	COG1923	regulation of RNA biosynthetic process
B7L41_RS13270	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B7L41_RS13275	COG0802	atpase or kinase
B7L41_RS13295	COG1187	pseudouridine synthase activity
B7L41_RS13310	COG0583	DNA-binding transcription factor activity
B7L41_RS13380	COG3409	Peptidoglycan-binding domain 1 protein
B7L41_RS13380	COG3267	Type II secretory pathway component ExeA
B7L41_RS13445	COG4373	Mu-like prophage FluMu protein gp28
B7L41_RS13455	COG4383	Mu-like prophage protein gp29
B7L41_RS13460	COG2369	cell adhesion
B7L41_RS13465	COG5005	Phage virion morphogenesis
B7L41_RS13480	COG4397	Mu-like prophage major head subunit gpT
B7L41_RS13575	COG2814	Major facilitator Superfamily
B7L41_RS13580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7L41_RS13590	COG2826	transposase and inactivated derivatives, IS30 family
B7L41_RS13615	COG0729	surface antigen
B7L41_RS13635	COG0174	glutamine synthetase
B7L41_RS13640	COG0745	RESPONSE REGULATOR receiver
B7L41_RS13645	COG2205	protein histidine kinase activity
B7L41_RS13655	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B7L41_RS13660	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B7L41_RS13685	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L41_RS13690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7L41_RS13695	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS13710	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L41_RS13715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L41_RS13735	COG0583	DNA-binding transcription factor activity
B7L41_RS13755	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7L41_RS13765	COG3658	cytochrome
B7L41_RS13770	COG1215	transferase activity, transferring glycosyl groups
B7L41_RS13775	COG0726	polysaccharide deacetylase
B7L41_RS13775	COG1649	PFAM Uncharacterised BCR, COG1649
B7L41_RS13805	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B7L41_RS13810	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7L41_RS13820	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7L41_RS13845	COG0305	Participates in initiation and elongation during chromosome replication
B7L41_RS13850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7L41_RS13860	COG1305	Transglutaminase-like
B7L41_RS13870	COG2308	Evidence 4 Homologs of previously reported genes of
B7L41_RS13900	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B7L41_RS13905	COG0138	bifunctional purine biosynthesis protein purh
B7L41_RS13910	COG0151	Belongs to the GarS family
B7L41_RS13920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7L41_RS13925	COG2011	ABC-type metal ion transport system permease component
B7L41_RS13930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L41_RS13940	COG1301	dicarboxylic acid transport
B7L41_RS13970	COG1794	racemase activity, acting on amino acids and derivatives
B7L41_RS13990	COG0745	RESPONSE REGULATOR receiver
B7L41_RS13995	COG0642	Histidine kinase
B7L41_RS14000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7L41_RS14010	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B7L41_RS14060	COG2351	hydroxyisourate hydrolase activity
B7L41_RS14070	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7L41_RS14070	COG3008	intermembrane lipid transfer
B7L41_RS14075	COG2995	paraquat-inducible protein a
B7L41_RS14100	COG0477	Major facilitator Superfamily
B7L41_RS14160	COG2186	Transcriptional regulator
B7L41_RS14175	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS14185	COG0583	DNA-binding transcription factor activity
B7L41_RS14195	COG0786	glutamate:sodium symporter activity
B7L41_RS14200	COG3243	poly(R)-hydroxyalkanoic acid synthase
B7L41_RS14230	COG3111	PFAM Bacterial OB fold (BOF) protein
B7L41_RS14330	COG1610	YqeY-like protein
B7L41_RS14335	COG4783	chaperone-mediated protein folding
B7L41_RS14360	COG1286	toxin biosynthetic process
B7L41_RS14390	COG0778	Nitroreductase
B7L41_RS14400	COG0513	Belongs to the DEAD box helicase family
B7L41_RS14420	COG2363	Small membrane protein
B7L41_RS14445	COG1234	tRNA 3'-trailer cleavage
B7L41_RS14450	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7L41_RS14460	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B7L41_RS14470	COG2819	hydrolase of the alpha beta superfamily
B7L41_RS14475	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS14480	COG1301	dicarboxylic acid transport
B7L41_RS14490	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7L41_RS14495	COG3139	Protein of unknown function (DUF1315)
B7L41_RS14500	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B7L41_RS14505	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7L41_RS14515	COG0494	nUDIX hydrolase
B7L41_RS14525	COG0642	Histidine kinase
B7L41_RS14540	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B7L41_RS14550	COG1720	tRNA m6t6A37 methyltransferase activity
B7L41_RS14565	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L41_RS14570	COG0826	peptidase U32
B7L41_RS14575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7L41_RS14590	COG4160	amino acid transport
B7L41_RS14595	COG4215	(ABC) transporter
B7L41_RS14610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L41_RS14710	COG0739	heme binding
B7L41_RS14835	COG5410	chromosome segregation
B7L41_RS14930	COG0305	Participates in initiation and elongation during chromosome replication
B7L41_RS14995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L41_RS15035	COG0582	viral genome integration into host DNA
B7L41_RS15040	COG1131	(ABC) transporter
B7L41_RS15045	COG0842	Transport permease protein
B7L41_RS15060	COG0772	Belongs to the SEDS family
B7L41_RS15065	COG2951	lytic endotransglycosylase activity
B7L41_RS15090	COG2207	Transcriptional regulator
B7L41_RS15105	COG0052	Belongs to the universal ribosomal protein uS2 family
B7L41_RS15110	COG0024	Methionine aminopeptidase
B7L41_RS15120	COG2223	nitrite transmembrane transporter activity
B7L41_RS15130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7L41_RS15135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7L41_RS15140	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS15155	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B7L41_RS15160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B7L41_RS15165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7L41_RS15195	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7L41_RS15200	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7L41_RS15205	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7L41_RS15240	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B7L41_RS15250	COG0174	glutamine synthetase
B7L41_RS15265	COG0512	Glutamine amidotransferase of anthranilate synthase
B7L41_RS15270	COG0308	aminopeptidase N
B7L41_RS15300	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7L41_RS15310	COG0302	gtp cyclohydrolase
B7L41_RS15330	COG3739	integral membrane protein
B7L41_RS15345	COG1169	isochorismate synthase
B7L41_RS15355	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B7L41_RS15365	COG1132	(ABC) transporter
B7L41_RS15370	COG1132	(ABC) transporter
B7L41_RS15380	COG1535	isochorismatase
B7L41_RS15380	COG3433	isochorismatase activity
B7L41_RS15385	COG1021	2,3-dihydroxybenzoate-AMP ligase
B7L41_RS15390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L41_RS15400	COG4774	siderophore transport
B7L41_RS15405	COG4607	ABC-type enterochelin transport system periplasmic component
B7L41_RS15410	COG4604	ABC transporter, ATP-binding protein
B7L41_RS15415	COG4605	iron ion homeostasis
B7L41_RS15420	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7L41_RS15425	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L41_RS15440	COG2964	Protein conserved in bacteria
B7L41_RS15450	COG1741	Belongs to the pirin family
B7L41_RS15505	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B7L41_RS15505	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7L41_RS15510	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L41_RS15515	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS15525	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L41_RS15530	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L41_RS15535	COG0006	proline dipeptidase activity
B7L41_RS15540	COG0583	DNA-binding transcription factor activity
B7L41_RS15550	COG2879	small protein
B7L41_RS15555	COG1966	Carbon starvation protein
B7L41_RS15575	COG4943	cyclic-guanylate-specific phosphodiesterase activity
B7L41_RS15600	COG1067	ATP-dependent peptidase activity
B7L41_RS15605	COG0583	DNA-binding transcription factor activity
B7L41_RS15630	COG1686	Belongs to the peptidase S11 family
B7L41_RS15635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B7L41_RS15670	COG0616	signal peptide processing
B7L41_RS15675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7L41_RS15685	COG0573	inorganic phosphate transmembrane transporter activity
B7L41_RS15690	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7L41_RS15695	COG1113	amino acid transport
B7L41_RS15700	COG3961	Belongs to the TPP enzyme family
B7L41_RS15705	COG1522	sequence-specific DNA binding
B7L41_RS15715	COG0076	glutamate decarboxylase activity
B7L41_RS15720	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7L41_RS15730	COG1309	transcriptional regulator
B7L41_RS15745	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L41_RS15780	COG0352	thiamine-phosphate diphosphorylase activity
B7L41_RS15805	COG1203	CRISPR-associated helicase, Cas3
B7L41_RS15835	COG0612	Peptidase, M16
B7L41_RS15845	COG1823	symporter activity
B7L41_RS15850	COG0583	DNA-binding transcription factor activity
B7L41_RS15855	COG0477	Major facilitator Superfamily
B7L41_RS15875	COG1187	pseudouridine synthase activity
B7L41_RS15890	COG1686	Belongs to the peptidase S11 family
B7L41_RS15895	COG1252	NADH dehydrogenase
B7L41_RS15905	COG0415	Belongs to the DNA photolyase family
B7L41_RS15920	COG1215	transferase activity, transferring glycosyl groups
B7L41_RS15950	COG2070	2-Nitropropane dioxygenase
B7L41_RS16005	COG0556	nucleotide-excision repair
B7L41_RS16025	COG0436	Aminotransferase
B7L41_RS16050	COG4221	oxidoreductase activity
B7L41_RS16060	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B7L41_RS16065	COG1381	Involved in DNA repair and RecF pathway recombination
B7L41_RS16075	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B7L41_RS16090	COG0681	Belongs to the peptidase S26 family
B7L41_RS16105	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7L41_RS16125	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7L41_RS16130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7L41_RS16135	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B7L41_RS16145	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B7L41_RS16150	COG4208	sulfate ABC transporter
B7L41_RS16155	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B7L41_RS16160	COG0583	DNA-binding transcription factor activity
B7L41_RS16165	COG4625	pathogenesis
B7L41_RS16180	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B7L41_RS16195	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B7L41_RS16205	COG1056	cytidyltransferase-related domain
B7L41_RS16205	COG1051	belongs to the nudix hydrolase family
B7L41_RS16210	COG1024	Enoyl-CoA hydratase
B7L41_RS16220	COG2814	Major facilitator Superfamily
B7L41_RS16225	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7L41_RS16225	COG0047	phosphoribosylformylglycinamidine synthase activity
B7L41_RS16245	COG1473	amidohydrolase
B7L41_RS16250	COG0824	Thioesterase
B7L41_RS16270	COG0823	Involved in the tonB-independent uptake of proteins
B7L41_RS16290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7L41_RS16325	COG0628	permease
B7L41_RS16335	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B7L41_RS16340	COG0596	Alpha beta hydrolase
B7L41_RS16345	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B7L41_RS16345	COG0616	signal peptide processing
B7L41_RS16355	COG2333	competence protein COMEC
B7L41_RS16355	COG0658	competence protein
B7L41_RS16360	COG1136	(ABC) transporter
B7L41_RS16365	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7L41_RS16395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L41_RS16415	COG0463	Glycosyl transferase, family 2
B7L41_RS16445	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B7L41_RS16450	COG1280	lysine exporter protein (LysE YggA)
B7L41_RS16455	COG2267	carboxylic ester hydrolase activity
B7L41_RS16465	COG0019	diaminopimelate decarboxylase activity
B7L41_RS16475	COG1113	amino acid transport
B7L41_RS16490	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
B7L41_RS16500	COG3339	Conserved Protein
B7L41_RS16505	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B7L41_RS16510	COG0243	molybdopterin cofactor binding
B7L41_RS16515	COG1929	Belongs to the glycerate kinase type-1 family
B7L41_RS16530	COG0778	Nitroreductase
B7L41_RS16570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L41_RS16585	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7L41_RS16610	COG0741	lytic transglycosylase activity
B7L41_RS16630	COG0584	glycerophosphoryl diester phosphodiesterase
B7L41_RS16635	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L41_RS16660	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7L41_RS16665	COG1597	lipid kinase activity
B7L41_RS16680	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7L41_RS16685	COG0477	Major facilitator Superfamily
B7L41_RS16735	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7L41_RS16740	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7L41_RS16770	COG0505	Belongs to the CarA family
B7L41_RS16790	COG0589	response to stress
B7L41_RS16805	COG2843	Capsule synthesis protein
B7L41_RS16830	COG2321	neutral zinc metallopeptidase
B7L41_RS16835	COG2354	Protein conserved in bacteria
B7L41_RS16875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7L41_RS16895	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7L41_RS16900	COG1053	succinate dehydrogenase
B7L41_RS16905	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B7L41_RS16910	COG2009	succinate dehydrogenase
B7L41_RS16945	COG2921	Belongs to the UPF0250 family
B7L41_RS16950	COG0321	lipoyl(octanoyl) transferase activity
B7L41_RS16965	COG0531	amino acid
B7L41_RS16975	COG1733	regulation of RNA biosynthetic process
B7L41_RS16980	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B7L41_RS16985	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7L41_RS16985	COG1648	precorrin-2 dehydrogenase activity
B7L41_RS17000	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B7L41_RS17030	COG0671	phosphoesterase, PA-phosphatase related
B7L41_RS17035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L41_RS17045	COG1538	Outer membrane efflux protein
B7L41_RS17050	COG0393	Putative heavy-metal-binding
B7L41_RS17055	COG0393	Putative heavy-metal-binding
B7L41_RS17065	COG1028	Short-chain dehydrogenase reductase Sdr
B7L41_RS17075	COG0525	valine-tRNA ligase activity
B7L41_RS17095	COG0583	DNA-binding transcription factor activity
B7L41_RS17105	COG0004	ammonium transporteR
B7L41_RS17115	COG0642	Histidine kinase
B7L41_RS17120	COG0745	RESPONSE REGULATOR receiver
B7L41_RS17125	COG2194	sulfuric ester hydrolase activity
B7L41_RS17145	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7L41_RS17160	COG2315	Protein conserved in bacteria
B7L41_RS17165	COG0142	geranyltranstransferase activity
B7L41_RS17170	COG2828	Protein conserved in bacteria
B7L41_RS17175	COG1113	amino acid transport
B7L41_RS17195	COG2207	Transcriptional regulator
B7L41_RS17220	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L41_RS17230	COG0560	Phosphoserine phosphatase
B7L41_RS17240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L41_RS17245	COG1530	ribonuclease E activity
B7L41_RS17250	COG0424	maF-like protein
B7L41_RS17255	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B7L41_RS17260	COG1792	Involved in formation and maintenance of cell shape
B7L41_RS17265	COG1077	Cell shape determining protein MreB Mrl
B7L41_RS17270	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7L41_RS17280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7L41_RS17305	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
B7L41_RS17310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7L41_RS17315	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7L41_RS17320	COG1115	amino acid carrier protein
B7L41_RS17335	COG2814	Major facilitator Superfamily
B7L41_RS17340	COG1289	transmembrane transporter activity
B7L41_RS17350	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B7L41_RS17390	COG1376	ErfK ybiS ycfS ynhG family protein
B7L41_RS17395	COG2832	Protein of unknown function (DUF454)
B7L41_RS17405	COG5510	response to toxic substance
B7L41_RS17420	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7L41_RS17435	COG0840	transmembrane signaling receptor activity
B7L41_RS17485	COG3422	double-strand break repair
B7L41_RS17490	COG2824	Alkylphosphonate utilization operon protein PhnA
B7L41_RS17495	COG3189	MarR family transcriptional regulator
B7L41_RS17505	COG0354	folic acid binding
B7L41_RS17510	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L41_RS17520	COG0679	Auxin Efflux Carrier
B7L41_RS17525	COG1902	pentaerythritol trinitrate reductase activity
B7L41_RS17530	COG4772	TonB-dependent receptor
B7L41_RS17535	COG2094	Belongs to the DNA glycosylase MPG family
B7L41_RS17560	COG1217	gtp-binding protein TYPA
B7L41_RS17565	COG2233	PERMEase
B7L41_RS17575	COG0833	amino acid
B7L41_RS17580	COG1690	Belongs to the RtcB family
B7L41_RS17585	COG2885	chlorophyll binding
B7L41_RS17585	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B7L41_RS17595	COG0183	Belongs to the thiolase family
B7L41_RS17615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L41_RS17635	COG2207	Transcriptional regulator
B7L41_RS17640	COG0183	Belongs to the thiolase family
B7L41_RS17660	COG2153	protein acetylation
B7L41_RS17670	COG1272	protein, Hemolysin III
B7L41_RS17675	COG0477	Major facilitator Superfamily
B7L41_RS17690	COG0450	alkyl hydroperoxide reductase
B7L41_RS17710	COG0285	dihydrofolate synthase activity
B7L41_RS17760	COG2096	Adenosyltransferase
B7L41_RS17780	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B7L41_RS17785	COG0745	RESPONSE REGULATOR receiver
B7L41_RS17790	COG2205	protein histidine kinase activity
B7L41_RS17800	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS17805	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS17875	COG0438	transferase activity, transferring glycosyl groups
B7L41_RS17880	COG0463	Glycosyl transferase, family 2
B7L41_RS17885	COG0726	polysaccharide deacetylase
B7L41_RS17905	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B7L41_RS17910	COG2205	protein histidine kinase activity
B7L41_RS17915	COG4695	Portal protein
B7L41_RS18055	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
B7L41_RS18070	COG3646	Phage regulatory protein
B7L41_RS18110	COG0629	single-stranded DNA binding
B7L41_RS18115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L41_RS18160	COG1862	Preprotein translocase
B7L41_RS18175	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7L41_RS18185	COG3781	membrane
B7L41_RS18190	COG0613	PHP domain protein
B7L41_RS18200	COG2350	Protein conserved in bacteria
B7L41_RS18230	COG1607	acyl-coa hydrolase
B7L41_RS18290	COG2199	diguanylate cyclase activity
B7L41_RS18300	COG1408	metallophosphoesterase
B7L41_RS18305	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7L41_RS18315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7L41_RS18335	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7L41_RS18340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B7L41_RS18355	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B7L41_RS18365	COG2969	positive regulation of protein catabolic process
B7L41_RS18385	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS18390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7L41_RS18405	COG1309	transcriptional regulator
B7L41_RS18410	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS18455	COG1183	phosphatidylcholine synthase activity
B7L41_RS18460	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B7L41_RS18490	COG1196	nuclear chromosome segregation
B7L41_RS18490	COG0741	lytic transglycosylase activity
B7L41_RS18490	COG0739	heme binding
B7L41_RS18500	COG1702	phosphate starvation-inducible protein PhoH
B7L41_RS18535	COG1295	ribonuclease BN
B7L41_RS18540	COG0697	spore germination
B7L41_RS18545	COG2169	Transcriptional regulator
B7L41_RS18550	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7L41_RS18595	COG0557	exoribonuclease II activity
B7L41_RS18600	COG0339	signal peptide processing
B7L41_RS18605	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
B7L41_RS18635	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B7L41_RS18640	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS18795	COG0626	cystathionine gamma-synthase activity
B7L41_RS18800	COG0433	COG0433 Predicted ATPase
B7L41_RS18805	COG1017	nitric oxide dioxygenase activity
B7L41_RS18805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L41_RS18810	COG1959	2 iron, 2 sulfur cluster binding
B7L41_RS18825	COG1301	dicarboxylic acid transport
B7L41_RS18830	COG1946	Acyl-CoA thioesterase
B7L41_RS18850	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7L41_RS18855	COG1040	competence protein
B7L41_RS18860	COG0494	nUDIX hydrolase
B7L41_RS18870	COG0598	Magnesium transport protein CorA
B7L41_RS18880	COG2854	intermembrane phospholipid transfer
B7L41_RS18890	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7L41_RS18895	COG1127	ABC transporter
B7L41_RS18900	COG0513	Belongs to the DEAD box helicase family
B7L41_RS18920	COG0408	coproporphyrinogen oxidase activity
B7L41_RS18935	COG1960	acyl-CoA dehydrogenase activity
B7L41_RS18945	COG1983	PspC domain protein
B7L41_RS18950	COG0517	IMP dehydrogenase activity
B7L41_RS19000	COG0583	DNA-binding transcription factor activity
B7L41_RS19020	COG1012	belongs to the aldehyde dehydrogenase family
B7L41_RS19030	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7L41_RS19035	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7L41_RS19040	COG0833	amino acid
B7L41_RS19070	COG1192	Involved in chromosome partitioning
B7L41_RS19075	COG0628	permease
B7L41_RS19085	COG1289	transmembrane transporter activity
B7L41_RS19100	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L41_RS19105	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B7L41_RS19115	COG0277	FAD linked oxidase domain protein
B7L41_RS19120	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7L41_RS19145	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B7L41_RS19150	COG5380	lipid catabolic process
B7L41_RS19170	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B7L41_RS19220	COG0194	GDP metabolic process
B7L41_RS19230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7L41_RS19250	COG3307	-O-antigen
B7L41_RS19265	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B7L41_RS19270	COG1704	LemA family
B7L41_RS19280	COG0493	'glutamate synthase
B7L41_RS19285	COG0069	glutamate synthase activity
B7L41_RS19285	COG0070	glutamate synthase
B7L41_RS19285	COG0067	glutamate synthase
B7L41_RS19335	COG2226	methyltransferase
B7L41_RS19350	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B7L41_RS19355	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B7L41_RS19400	COG0833	amino acid
B7L41_RS19465	COG0488	(ABC) transporter
B7L41_RS19470	COG2873	o-acetylhomoserine
B7L41_RS19475	COG4221	oxidoreductase activity
B7L41_RS19480	COG0659	secondary active sulfate transmembrane transporter activity