locus-tag	class	description
B7L39_RS00010	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
B7L39_RS00015	COG0735	belongs to the Fur family
B7L39_RS00040	COG0420	3'-5' exonuclease activity
B7L39_RS00060	COG1090	epimerase
B7L39_RS00075	COG2050	protein possibly involved in aromatic compounds catabolism
B7L39_RS00085	COG2814	Major facilitator Superfamily
B7L39_RS00090	COG0405	Gamma-glutamyltransferase
B7L39_RS00120	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L39_RS00230	COG1484	DNA-dependent DNA replication
B7L39_RS00275	COG3755	Protein conserved in bacteria
B7L39_RS00425	COG2026	Addiction module toxin, RelE StbE family
B7L39_RS00465	COG0592	DNA-directed DNA polymerase activity
B7L39_RS00555	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7L39_RS00620	COG0477	Major facilitator Superfamily
B7L39_RS00625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L39_RS00635	COG1595	DNA-templated transcription, initiation
B7L39_RS00690	COG0531	amino acid
B7L39_RS00695	COG2040	homocysteine
B7L39_RS00720	COG1309	transcriptional regulator
B7L39_RS00725	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L39_RS00730	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L39_RS00740	COG1607	acyl-coa hydrolase
B7L39_RS00750	COG0523	cobalamin synthesis protein
B7L39_RS00760	COG4681	YaeQ
B7L39_RS00770	COG1649	PFAM Uncharacterised BCR, COG1649
B7L39_RS00770	COG0726	polysaccharide deacetylase
B7L39_RS00775	COG1215	transferase activity, transferring glycosyl groups
B7L39_RS00785	COG1024	Enoyl-CoA hydratase
B7L39_RS00800	COG1414	Transcriptional regulator
B7L39_RS00820	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS00830	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L39_RS00835	COG2271	Major facilitator Superfamily
B7L39_RS00845	COG2267	carboxylic ester hydrolase activity
B7L39_RS00850	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS00865	COG0028	Belongs to the TPP enzyme family
B7L39_RS00875	COG0477	Major facilitator Superfamily
B7L39_RS00880	COG0242	peptide deformylase activity
B7L39_RS00885	COG2066	Belongs to the glutaminase family
B7L39_RS00890	COG2207	Transcriptional regulator
B7L39_RS00895	COG2223	nitrite transmembrane transporter activity
B7L39_RS00915	COG0583	DNA-binding transcription factor activity
B7L39_RS00920	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS00925	COG2271	Major facilitator Superfamily
B7L39_RS00930	COG3959	Transketolase, thiamine diphosphate binding domain
B7L39_RS00935	COG3958	Transketolase
B7L39_RS00945	COG0306	phosphate transporter
B7L39_RS00960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
B7L39_RS01005	COG4181	ATPase activity
B7L39_RS01010	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
B7L39_RS01035	COG0583	DNA-binding transcription factor activity
B7L39_RS01045	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L39_RS01050	COG1773	rubredoxin
B7L39_RS01095	COG2851	Citrate transporter
B7L39_RS01105	COG1253	flavin adenine dinucleotide binding
B7L39_RS01145	COG0804	urea catabolic process
B7L39_RS01150	COG0804	urea catabolic process
B7L39_RS01160	COG0830	nickel cation binding
B7L39_RS01175	COG0742	ribosomal rna small subunit methyltransferase
B7L39_RS01180	COG0768	penicillin binding
B7L39_RS01200	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
B7L39_RS01205	COG2878	Part of a membrane complex involved in electron transport
B7L39_RS01210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7L39_RS01220	COG3384	dioxygenase
B7L39_RS01245	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B7L39_RS01570	COG0739	heme binding
B7L39_RS01615	COG2194	sulfuric ester hydrolase activity
B7L39_RS01650	COG0006	proline dipeptidase activity
B7L39_RS01655	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L39_RS01660	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L39_RS01680	COG1279	arginine transmembrane transporter activity
B7L39_RS01685	COG0583	DNA-binding transcription factor activity
B7L39_RS01725	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L39_RS01730	COG1388	LysM domain
B7L39_RS01730	COG0741	lytic transglycosylase activity
B7L39_RS01730	COG0741	lytic transglycosylase activity
B7L39_RS01730	COG1388	LysM domain
B7L39_RS01740	COG4174	ABC transporter (Permease)
B7L39_RS01745	COG4239	(ABC) transporter, permease
B7L39_RS01750	COG4172	Belongs to the ABC transporter superfamily
B7L39_RS01770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
B7L39_RS01780	COG2203	Gaf domain
B7L39_RS01780	COG3706	GGDEF domain
B7L39_RS01780	COG4251	negative regulation of phosphorylation
B7L39_RS01780	COG5001	Diguanylate cyclase
B7L39_RS01790	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L39_RS01790	COG1902	pentaerythritol trinitrate reductase activity
B7L39_RS01805	COG4269	membrane
B7L39_RS01835	COG3209	COG3209 Rhs family protein
B7L39_RS01880	COG1113	amino acid transport
B7L39_RS01890	COG0531	amino acid
B7L39_RS01905	COG2072	flavoprotein involved in K transport
B7L39_RS01910	COG0300	oxidoreductase activity
B7L39_RS01920	COG1309	transcriptional regulator
B7L39_RS01925	COG1741	Belongs to the pirin family
B7L39_RS01940	COG2072	flavoprotein involved in K transport
B7L39_RS01950	COG2252	PERMEase
B7L39_RS01955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
B7L39_RS01960	COG3038	cytochrome b561
B7L39_RS01970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B7L39_RS01980	COG0527	aspartate kinase activity
B7L39_RS01990	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
B7L39_RS02000	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
B7L39_RS02015	COG0667	Aldo Keto reductase
B7L39_RS02030	COG1765	OsmC-like protein
B7L39_RS02050	COG0542	response to heat
B7L39_RS02085	COG2885	chlorophyll binding
B7L39_RS02095	COG0625	glutathione transferase activity
B7L39_RS02100	COG0220	tRNA (guanine-N7-)-methyltransferase activity
B7L39_RS02120	COG3634	alkyl hydroperoxide reductase activity
B7L39_RS02130	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
B7L39_RS02140	COG0450	alkyl hydroperoxide reductase
B7L39_RS02145	COG1643	Atp-dependent helicase
B7L39_RS02160	COG2814	Major facilitator Superfamily
B7L39_RS02165	COG3135	benzoate transporter
B7L39_RS02170	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS02175	COG0633	Ferredoxin
B7L39_RS02175	COG0543	2 iron, 2 sulfur cluster binding
B7L39_RS02180	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B7L39_RS02185	COG4638	Rieske (2fe-2S)
B7L39_RS02190	COG0583	DNA-binding transcription factor activity
B7L39_RS02245	COG1570	exodeoxyribonuclease VII activity
B7L39_RS02280	COG1280	lysine exporter protein (LysE YggA)
B7L39_RS02285	COG1278	Cold shock
B7L39_RS02320	COG2814	Major facilitator Superfamily
B7L39_RS02360	COG0517	IMP dehydrogenase activity
B7L39_RS02360	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
B7L39_RS02365	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
B7L39_RS02375	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
B7L39_RS02380	COG1137	ATPase activity
B7L39_RS02385	COG1538	Outer membrane efflux protein
B7L39_RS02415	COG4122	O-methyltransferase activity
B7L39_RS02425	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
B7L39_RS02440	COG1522	sequence-specific DNA binding
B7L39_RS02445	COG5006	permease, DMT superfamily
B7L39_RS02455	COG1560	Kdo2-lipid A biosynthetic process
B7L39_RS02470	COG2814	Major facilitator Superfamily
B7L39_RS02490	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7L39_RS02545	COG1765	OsmC-like protein
B7L39_RS02565	COG0583	DNA-binding transcription factor activity
B7L39_RS02570	COG1914	H( )-stimulated, divalent metal cation uptake system
B7L39_RS02590	COG4770	biotin carboxylase activity
B7L39_RS02595	COG0038	chloride channel
B7L39_RS02625	COG1309	transcriptional regulator
B7L39_RS02635	COG1063	alcohol dehydrogenase
B7L39_RS02650	COG0439	Biotin carboxylase
B7L39_RS02655	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L39_RS02660	COG1733	regulation of RNA biosynthetic process
B7L39_RS02675	COG0864	Transcriptional regulator
B7L39_RS02685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7L39_RS02690	COG1116	anion transmembrane transporter activity
B7L39_RS02815	COG0590	tRNA wobble adenosine to inosine editing
B7L39_RS02820	COG2807	transmembrane transport
B7L39_RS02835	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
B7L39_RS02850	COG0789	Transcriptional regulator
B7L39_RS02865	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L39_RS02885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7L39_RS02895	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L39_RS02910	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS02915	COG0531	amino acid
B7L39_RS02920	COG1760	l-serine dehydratase
B7L39_RS02925	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS02925	COG2030	dehydratase
B7L39_RS02930	COG3396	Phenylacetate-CoA oxygenase
B7L39_RS02935	COG3460	Phenylacetate-CoA oxygenase
B7L39_RS02940	COG3396	Phenylacetate-CoA oxygenase
B7L39_RS02945	COG2151	metal-sulfur cluster biosynthetic enzyme
B7L39_RS02950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L39_RS02955	COG1024	Enoyl-CoA hydratase
B7L39_RS02960	COG1024	Enoyl-CoA hydratase
B7L39_RS02965	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7L39_RS02970	COG0183	Belongs to the thiolase family
B7L39_RS02975	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
B7L39_RS02980	COG3327	negative regulation of DNA-templated transcription, initiation
B7L39_RS02990	COG2050	protein possibly involved in aromatic compounds catabolism
B7L39_RS03030	COG0753	catalase activity
B7L39_RS03035	COG3038	cytochrome b561
B7L39_RS03055	COG2267	carboxylic ester hydrolase activity
B7L39_RS03060	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L39_RS03065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7L39_RS03070	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS03075	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B7L39_RS03085	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS03090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7L39_RS03095	COG0583	DNA-binding transcription factor activity
B7L39_RS03105	COG1414	Transcriptional regulator
B7L39_RS03110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L39_RS03120	COG1840	ABC-type Fe3 transport system, periplasmic component
B7L39_RS03125	COG3842	ATPase activity
B7L39_RS03140	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
B7L39_RS03145	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B7L39_RS03150	COG2814	Major facilitator Superfamily
B7L39_RS03155	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS03170	COG1024	Enoyl-CoA hydratase
B7L39_RS03180	COG2814	Major facilitator Superfamily
B7L39_RS03190	COG0183	Belongs to the thiolase family
B7L39_RS03195	COG1250	3-hydroxyacyl-CoA dehydrogenase
B7L39_RS03200	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS03205	COG1024	Enoyl-CoA hydratase
B7L39_RS03210	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS03215	COG2814	Major facilitator Superfamily
B7L39_RS03220	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7L39_RS03225	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L39_RS03235	COG2814	Major facilitator Superfamily
B7L39_RS03245	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS03260	COG0583	DNA-binding transcription factor activity
B7L39_RS03270	COG4770	biotin carboxylase activity
B7L39_RS03275	COG1024	Enoyl-CoA hydratase
B7L39_RS03280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7L39_RS03285	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS03290	COG1309	transcriptional regulator
B7L39_RS03295	COG0318	PFAM AMP-dependent synthetase and ligase
B7L39_RS03315	COG0583	DNA-binding transcription factor activity
B7L39_RS03360	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS03380	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
B7L39_RS03400	COG0784	Response regulator, receiver
B7L39_RS03400	COG2205	protein histidine kinase activity
B7L39_RS03415	COG0765	amino acid transport
B7L39_RS03420	COG0765	amino acid transport
B7L39_RS03425	COG1126	abc transporter atp-binding protein
B7L39_RS03430	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7L39_RS03435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B7L39_RS03445	COG1280	lysine exporter protein (LysE YggA)
B7L39_RS03450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B7L39_RS03455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7L39_RS03460	COG1045	serine acetyltransferase
B7L39_RS03475	COG0583	DNA-binding transcription factor activity
B7L39_RS03480	COG0625	glutathione transferase activity
B7L39_RS03485	COG0625	glutathione transferase activity
B7L39_RS03490	COG0583	DNA-binding transcription factor activity
B7L39_RS03500	COG1346	cytolysis
B7L39_RS03520	COG2814	Major facilitator Superfamily
B7L39_RS03530	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
B7L39_RS03535	COG3052	prosthetic group binding
B7L39_RS03555	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
B7L39_RS03575	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L39_RS03580	COG1294	oxidase, subunit
B7L39_RS03585	COG1271	oxidase subunit
B7L39_RS03610	COG0477	Major facilitator Superfamily
B7L39_RS03620	COG4521	taurine ABC transporter
B7L39_RS03625	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
B7L39_RS03630	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L39_RS03635	COG2175	clavaminate synthase activity
B7L39_RS03645	COG1953	Uracil, thiamine, allantoin
B7L39_RS03655	COG0583	DNA-binding transcription factor activity
B7L39_RS03665	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
B7L39_RS03680	COG0640	Transcriptional regulator
B7L39_RS03685	COG0798	PFAM Bile acid sodium symporter
B7L39_RS03690	COG0583	DNA-binding transcription factor activity
B7L39_RS03705	COG3634	alkyl hydroperoxide reductase activity
B7L39_RS03745	COG0436	Aminotransferase
B7L39_RS03755	COG0386	Belongs to the glutathione peroxidase family
B7L39_RS03795	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7L39_RS03820	COG0012	GTP binding
B7L39_RS03825	COG2011	ABC-type metal ion transport system permease component
B7L39_RS03830	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7L39_RS03840	COG1464	Belongs to the NlpA lipoprotein family
B7L39_RS03870	COG0765	amino acid transport
B7L39_RS03875	COG0765	amino acid transport
B7L39_RS03880	COG1126	abc transporter atp-binding protein
B7L39_RS03890	COG1522	sequence-specific DNA binding
B7L39_RS03905	COG1309	transcriptional regulator
B7L39_RS03925	COG0583	DNA-binding transcription factor activity
B7L39_RS03935	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
B7L39_RS03945	COG0697	spore germination
B7L39_RS03975	COG3121	Chaperone
B7L39_RS03980	COG3539	Fimbrial protein
B7L39_RS04005	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
B7L39_RS04005	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
B7L39_RS04050	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
B7L39_RS04060	COG2353	YceI-like domain
B7L39_RS04070	COG3698	Phosphodiester glycosidase
B7L39_RS04085	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
B7L39_RS04090	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7L39_RS04090	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
B7L39_RS04090	COG0506	proline dehydrogenase activity
B7L39_RS04100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7L39_RS04105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B7L39_RS04125	COG1132	(ABC) transporter
B7L39_RS04130	COG3122	Protein conserved in bacteria
B7L39_RS04135	COG3619	membrane
B7L39_RS04150	COG0640	Transcriptional regulator
B7L39_RS04160	COG2850	peptidyl-arginine hydroxylation
B7L39_RS04165	COG0424	maF-like protein
B7L39_RS04185	COG0191	fructose-bisphosphate aldolase activity
B7L39_RS04190	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7L39_RS04205	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
B7L39_RS04215	COG1192	Involved in chromosome partitioning
B7L39_RS04220	COG1475	DNA binding
B7L39_RS04225	COG0811	peptide transport
B7L39_RS04235	COG1132	(ABC) transporter
B7L39_RS04240	COG1663	tetraacyldisaccharide 4'-kinase activity
B7L39_RS04260	COG0084	hydrolase, TatD family'
B7L39_RS04325	COG0776	regulation of translation
B7L39_RS04355	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
B7L39_RS04360	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
B7L39_RS04405	COG0339	signal peptide processing
B7L39_RS04415	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B7L39_RS04450	COG0702	epimerase
B7L39_RS04455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B7L39_RS04475	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
B7L39_RS04505	COG0316	Belongs to the HesB IscA family
B7L39_RS04510	COG0822	iron-sulfur transferase activity
B7L39_RS04535	COG0776	regulation of translation
B7L39_RS04540	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
B7L39_RS04545	COG2207	Transcriptional regulator
B7L39_RS04550	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7L39_RS04555	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS04560	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS04575	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B7L39_RS04595	COG4264	IucA IucC family
B7L39_RS04600	COG4264	IucA IucC family
B7L39_RS04655	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
B7L39_RS04675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B7L39_RS04680	COG0730	response to heat
B7L39_RS04700	COG4773	Receptor
B7L39_RS04705	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7L39_RS04720	COG1131	(ABC) transporter
B7L39_RS04725	COG0842	Transport permease protein
B7L39_RS04730	COG0842	Transport permease protein
B7L39_RS04785	COG2226	methyltransferase
B7L39_RS04810	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
B7L39_RS04840	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7L39_RS04850	COG0133	tryptophan synthase activity
B7L39_RS04865	COG3706	GGDEF domain
B7L39_RS04880	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7L39_RS04885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
B7L39_RS04890	COG0022	dehydrogenase e1 component
B7L39_RS04895	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7L39_RS04900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7L39_RS04910	COG1063	alcohol dehydrogenase
B7L39_RS04915	COG3781	membrane
B7L39_RS04925	COG3453	Protein conserved in bacteria
B7L39_RS04925	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L39_RS04935	COG0730	response to heat
B7L39_RS04950	COG2207	Transcriptional regulator
B7L39_RS04950	COG3708	Transcriptional regulator
B7L39_RS04955	COG1733	regulation of RNA biosynthetic process
B7L39_RS04960	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
B7L39_RS04970	COG2188	Transcriptional regulator
B7L39_RS04985	COG4521	taurine ABC transporter
B7L39_RS04990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L39_RS05010	COG0477	Major facilitator Superfamily
B7L39_RS05020	COG1027	Aspartate ammonia-lyase
B7L39_RS05035	COG0583	DNA-binding transcription factor activity
B7L39_RS05040	COG0583	DNA-binding transcription factor activity
B7L39_RS05045	COG0183	Belongs to the thiolase family
B7L39_RS05050	COG2031	fatty acid transporter
B7L39_RS05055	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L39_RS05065	COG0583	DNA-binding transcription factor activity
B7L39_RS05075	COG2610	gluconate transmembrane transporter activity
B7L39_RS05080	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS05090	COG2207	Transcriptional regulator
B7L39_RS05105	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS05130	COG0543	2 iron, 2 sulfur cluster binding
B7L39_RS05130	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L39_RS05135	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
B7L39_RS05140	COG4638	Rieske (2fe-2S)
B7L39_RS05150	COG0725	ABC transporter, periplasmic molybdate-binding protein
B7L39_RS05155	COG4149	molybdate abc transporter
B7L39_RS05160	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
B7L39_RS05165	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS05170	COG3433	isochorismatase activity
B7L39_RS05170	COG1535	isochorismatase
B7L39_RS05230	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7L39_RS05245	COG0753	catalase activity
B7L39_RS05255	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
B7L39_RS05285	COG3539	Fimbrial protein
B7L39_RS05305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7L39_RS05325	COG2072	flavoprotein involved in K transport
B7L39_RS05335	COG1538	Outer membrane efflux protein
B7L39_RS05340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
B7L39_RS05345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L39_RS05350	COG0745	RESPONSE REGULATOR receiver
B7L39_RS05355	COG2205	protein histidine kinase activity
B7L39_RS05365	COG2207	Transcriptional regulator
B7L39_RS05380	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS05430	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
B7L39_RS05550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7L39_RS05570	COG1120	ATPase activity
B7L39_RS05575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7L39_RS05585	COG1064	alcohol dehydrogenase
B7L39_RS05600	COG2207	Transcriptional regulator
B7L39_RS05605	COG2084	Dehydrogenase
B7L39_RS05615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
B7L39_RS05620	COG0583	DNA-binding transcription factor activity
B7L39_RS05630	COG0129	dihydroxy-acid dehydratase activity
B7L39_RS05635	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS05650	COG1566	PFAM secretion protein HlyD family protein
B7L39_RS05670	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
B7L39_RS05700	COG0583	DNA-binding transcription factor activity
B7L39_RS05715	COG2188	Transcriptional regulator
B7L39_RS05740	COG3210	domain, Protein
B7L39_RS05745	COG2831	hemolysin activation secretion protein
B7L39_RS05760	COG1473	amidohydrolase
B7L39_RS05770	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7L39_RS05770	COG0475	glutathione-regulated potassium exporter activity
B7L39_RS05780	COG0583	DNA-binding transcription factor activity
B7L39_RS05785	COG1335	isochorismatase
B7L39_RS05795	COG1309	transcriptional regulator
B7L39_RS05825	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
B7L39_RS05835	COG1902	pentaerythritol trinitrate reductase activity
B7L39_RS05835	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L39_RS05840	COG1846	Transcriptional regulator
B7L39_RS05865	COG0753	catalase activity
B7L39_RS05880	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS05895	COG3162	membrane
B7L39_RS05905	COG3829	transcription factor binding
B7L39_RS05915	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS05935	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS05955	COG2186	Transcriptional regulator
B7L39_RS05965	COG0583	DNA-binding transcription factor activity
B7L39_RS05970	COG4948	Mandelate Racemase Muconate Lactonizing
B7L39_RS05975	COG4829	muconolactone delta-isomerase
B7L39_RS05985	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7L39_RS05990	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L39_RS05995	COG0183	Belongs to the thiolase family
B7L39_RS06000	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7L39_RS06010	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS06020	COG3733	amine oxidase
B7L39_RS06030	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L39_RS06040	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS06050	COG4638	Rieske (2fe-2S)
B7L39_RS06070	COG0154	amidase activity
B7L39_RS06080	COG2814	Major facilitator Superfamily
B7L39_RS06105	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS06110	COG0583	DNA-binding transcription factor activity
B7L39_RS06115	COG1414	Transcriptional regulator
B7L39_RS06130	COG2391	methyltransferase activity
B7L39_RS06140	COG4993	Dehydrogenase
B7L39_RS06145	COG3659	wide pore channel activity
B7L39_RS06150	COG3420	alginic acid biosynthetic process
B7L39_RS06155	COG0710	3-dehydroquinate dehydratase activity
B7L39_RS06160	COG3485	protocatechuate 3,4-dioxygenase
B7L39_RS06165	COG3485	protocatechuate 3,4-dioxygenase
B7L39_RS06170	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
B7L39_RS06175	COG2271	Major facilitator Superfamily
B7L39_RS06180	COG0596	Alpha beta hydrolase
B7L39_RS06185	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B7L39_RS06190	COG0183	Belongs to the thiolase family
B7L39_RS06195	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
B7L39_RS06200	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
B7L39_RS06210	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
B7L39_RS06215	COG2323	membrane
B7L39_RS06265	COG0446	pyridine nucleotide-disulphide oxidoreductase
B7L39_RS06265	COG1902	pentaerythritol trinitrate reductase activity
B7L39_RS06290	COG0542	response to heat
B7L39_RS06295	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
B7L39_RS06325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7L39_RS06330	COG0569	domain protein
B7L39_RS06335	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
B7L39_RS06350	COG4774	siderophore transport
B7L39_RS06355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B7L39_RS06365	COG1585	Membrane protein implicated in regulation of membrane protease activity
B7L39_RS06380	COG1294	oxidase, subunit
B7L39_RS06385	COG4890	Cyd operon protein YbgT
B7L39_RS06400	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
B7L39_RS06410	COG0552	protein localization to endoplasmic reticulum
B7L39_RS06440	COG0516	GMP reductase activity
B7L39_RS06440	COG0517	IMP dehydrogenase activity
B7L39_RS06445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7L39_RS06450	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
B7L39_RS06460	COG0583	DNA-binding transcription factor activity
B7L39_RS06465	COG0024	Methionine aminopeptidase
B7L39_RS06500	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7L39_RS06500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B7L39_RS06510	COG1105	Belongs to the carbohydrate kinase PfkB family
B7L39_RS06515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7L39_RS06515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
B7L39_RS06515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B7L39_RS06535	COG3300	MHYT domain
B7L39_RS06535	COG5001	Diguanylate cyclase
B7L39_RS06550	COG2135	peptidase activity
B7L39_RS06555	COG0659	secondary active sulfate transmembrane transporter activity
B7L39_RS06570	COG1113	amino acid transport
B7L39_RS06580	COG1522	sequence-specific DNA binding
B7L39_RS06605	COG1011	Hydrolase
B7L39_RS06610	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
B7L39_RS06620	COG2137	regulation of response to DNA damage stimulus
B7L39_RS06635	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7L39_RS06670	COG0575	Belongs to the CDS family
B7L39_RS06675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
B7L39_RS06700	COG3852	Histidine kinase
B7L39_RS06705	COG2204	response regulator
B7L39_RS06765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7L39_RS06770	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
B7L39_RS06790	COG0697	spore germination
B7L39_RS06795	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L39_RS06805	COG0303	'Molybdopterin
B7L39_RS06810	COG0315	cyclic pyranopterin monophosphate synthase activity
B7L39_RS06810	COG0521	Mo-molybdopterin cofactor biosynthetic process
B7L39_RS06825	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
B7L39_RS06830	COG0243	molybdopterin cofactor binding
B7L39_RS06840	COG0243	molybdopterin cofactor binding
B7L39_RS06845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L39_RS06850	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L39_RS06850	COG2146	nitrite reductase [NAD(P)H] activity
B7L39_RS06860	COG0745	RESPONSE REGULATOR receiver
B7L39_RS06865	COG1116	anion transmembrane transporter activity
B7L39_RS06865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L39_RS06880	COG0511	ligase activity, forming carbon-carbon bonds
B7L39_RS06895	COG2814	Major facilitator Superfamily
B7L39_RS06915	COG0069	glutamate synthase activity
B7L39_RS06935	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B7L39_RS06945	COG1454	alcohol dehydrogenase
B7L39_RS06950	COG0824	Thioesterase
B7L39_RS06960	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B7L39_RS06975	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7L39_RS06980	COG2030	dehydratase
B7L39_RS06990	COG0183	Belongs to the thiolase family
B7L39_RS07000	COG0583	DNA-binding transcription factor activity
B7L39_RS07005	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B7L39_RS07015	COG1522	sequence-specific DNA binding
B7L39_RS07020	COG3135	benzoate transporter
B7L39_RS07030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B7L39_RS07045	COG0589	response to stress
B7L39_RS07050	COG0488	(ABC) transporter
B7L39_RS07065	COG4773	Receptor
B7L39_RS07100	COG0668	transmembrane transport
B7L39_RS07110	COG1309	transcriptional regulator
B7L39_RS07130	COG1605	Chorismate mutase
B7L39_RS07140	COG4221	oxidoreductase activity
B7L39_RS07150	COG0308	aminopeptidase N
B7L39_RS07170	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
B7L39_RS07180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7L39_RS07185	COG1454	alcohol dehydrogenase
B7L39_RS07205	COG0531	amino acid
B7L39_RS07210	COG4303	Ethanolamine ammonia lyase large subunit
B7L39_RS07215	COG4302	ethanolamine ammonia-lyase activity
B7L39_RS07220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7L39_RS07220	COG0519	Catalyzes the synthesis of GMP from XMP
B7L39_RS07225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7L39_RS07235	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
B7L39_RS07250	COG0697	spore germination
B7L39_RS07255	COG1923	regulation of RNA biosynthetic process
B7L39_RS07265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
B7L39_RS07270	COG0802	atpase or kinase
B7L39_RS07290	COG1187	pseudouridine synthase activity
B7L39_RS07305	COG0583	DNA-binding transcription factor activity
B7L39_RS07320	COG2814	Major facilitator Superfamily
B7L39_RS07325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B7L39_RS07355	COG0729	surface antigen
B7L39_RS07375	COG0174	glutamine synthetase
B7L39_RS07380	COG0745	RESPONSE REGULATOR receiver
B7L39_RS07385	COG2205	protein histidine kinase activity
B7L39_RS07395	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
B7L39_RS07400	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
B7L39_RS07425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L39_RS07430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7L39_RS07435	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS07450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L39_RS07455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L39_RS07475	COG0583	DNA-binding transcription factor activity
B7L39_RS07495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7L39_RS07505	COG3658	cytochrome
B7L39_RS07510	COG1215	transferase activity, transferring glycosyl groups
B7L39_RS07515	COG0726	polysaccharide deacetylase
B7L39_RS07515	COG1649	PFAM Uncharacterised BCR, COG1649
B7L39_RS07540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
B7L39_RS07545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
B7L39_RS07555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
B7L39_RS07580	COG0305	Participates in initiation and elongation during chromosome replication
B7L39_RS07585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B7L39_RS07595	COG1305	Transglutaminase-like
B7L39_RS07605	COG2308	Evidence 4 Homologs of previously reported genes of
B7L39_RS07635	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
B7L39_RS07640	COG0138	bifunctional purine biosynthesis protein purh
B7L39_RS07645	COG0151	Belongs to the GarS family
B7L39_RS07650	COG1464	Belongs to the NlpA lipoprotein family
B7L39_RS07655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
B7L39_RS07660	COG2011	ABC-type metal ion transport system permease component
B7L39_RS07665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L39_RS07675	COG1301	dicarboxylic acid transport
B7L39_RS07715	COG2433	Pfam Transposase IS66
B7L39_RS07725	COG3173	Aminoglycoside phosphotransferase
B7L39_RS07730	COG0488	(ABC) transporter
B7L39_RS07745	COG0482	sulfurtransferase activity
B7L39_RS07815	COG1794	racemase activity, acting on amino acids and derivatives
B7L39_RS07825	COG3008	intermembrane lipid transfer
B7L39_RS07825	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
B7L39_RS07830	COG2995	paraquat-inducible protein a
B7L39_RS07840	COG2985	domain, Protein
B7L39_RS07870	COG0477	Major facilitator Superfamily
B7L39_RS07935	COG2186	Transcriptional regulator
B7L39_RS07945	COG0786	glutamate:sodium symporter activity
B7L39_RS07950	COG3243	poly(R)-hydroxyalkanoic acid synthase
B7L39_RS07975	COG3111	PFAM Bacterial OB fold (BOF) protein
B7L39_RS08075	COG1610	YqeY-like protein
B7L39_RS08080	COG4783	chaperone-mediated protein folding
B7L39_RS08105	COG1286	toxin biosynthetic process
B7L39_RS08135	COG0778	Nitroreductase
B7L39_RS08145	COG0513	Belongs to the DEAD box helicase family
B7L39_RS08165	COG2363	Small membrane protein
B7L39_RS08195	COG1234	tRNA 3'-trailer cleavage
B7L39_RS08200	COG2195	Cleaves the N-terminal amino acid of tripeptides
B7L39_RS08210	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
B7L39_RS08220	COG2819	hydrolase of the alpha beta superfamily
B7L39_RS08225	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS08230	COG1301	dicarboxylic acid transport
B7L39_RS08240	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B7L39_RS08245	COG3139	Protein of unknown function (DUF1315)
B7L39_RS08250	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
B7L39_RS08255	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B7L39_RS08265	COG0494	nUDIX hydrolase
B7L39_RS08275	COG0642	Histidine kinase
B7L39_RS08290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
B7L39_RS08300	COG1720	tRNA m6t6A37 methyltransferase activity
B7L39_RS08315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L39_RS08320	COG0826	peptidase U32
B7L39_RS08325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7L39_RS08335	COG4598	ABC transporter
B7L39_RS08340	COG4160	amino acid transport
B7L39_RS08345	COG4215	(ABC) transporter
B7L39_RS08360	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L39_RS08405	COG1131	(ABC) transporter
B7L39_RS08410	COG0842	Transport permease protein
B7L39_RS08425	COG0772	Belongs to the SEDS family
B7L39_RS08430	COG2951	lytic endotransglycosylase activity
B7L39_RS08470	COG0052	Belongs to the universal ribosomal protein uS2 family
B7L39_RS08475	COG0024	Methionine aminopeptidase
B7L39_RS08485	COG2223	nitrite transmembrane transporter activity
B7L39_RS08495	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7L39_RS08500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
B7L39_RS08505	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS08520	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
B7L39_RS08525	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B7L39_RS08530	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7L39_RS08550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7L39_RS08555	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B7L39_RS08560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
B7L39_RS08595	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
B7L39_RS08605	COG0174	glutamine synthetase
B7L39_RS08620	COG0512	Glutamine amidotransferase of anthranilate synthase
B7L39_RS08625	COG0308	aminopeptidase N
B7L39_RS08655	COG1529	Aldehyde oxidase and xanthine dehydrogenase
B7L39_RS08665	COG0302	gtp cyclohydrolase
B7L39_RS08690	COG3739	integral membrane protein
B7L39_RS08705	COG1169	isochorismate synthase
B7L39_RS08715	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
B7L39_RS08720	COG1132	(ABC) transporter
B7L39_RS08725	COG1132	(ABC) transporter
B7L39_RS08735	COG1535	isochorismatase
B7L39_RS08735	COG3433	isochorismatase activity
B7L39_RS08740	COG1021	2,3-dihydroxybenzoate-AMP ligase
B7L39_RS08745	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L39_RS08755	COG4774	siderophore transport
B7L39_RS08760	COG4607	ABC-type enterochelin transport system periplasmic component
B7L39_RS08765	COG4604	ABC transporter, ATP-binding protein
B7L39_RS08770	COG4605	iron ion homeostasis
B7L39_RS08775	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
B7L39_RS08780	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L39_RS08795	COG2964	Protein conserved in bacteria
B7L39_RS08805	COG1741	Belongs to the pirin family
B7L39_RS08825	COG1309	transcriptional regulator
B7L39_RS08835	COG4948	Mandelate Racemase Muconate Lactonizing
B7L39_RS08840	COG2814	Major facilitator Superfamily
B7L39_RS08875	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
B7L39_RS08875	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
B7L39_RS08880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L39_RS08885	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS08895	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L39_RS08900	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L39_RS08905	COG0583	DNA-binding transcription factor activity
B7L39_RS08910	COG1113	amino acid transport
B7L39_RS08930	COG2508	Transcriptional regulator
B7L39_RS08930	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
B7L39_RS08970	COG2879	small protein
B7L39_RS08975	COG1966	Carbon starvation protein
B7L39_RS09020	COG1067	ATP-dependent peptidase activity
B7L39_RS09025	COG0583	DNA-binding transcription factor activity
B7L39_RS09050	COG1686	Belongs to the peptidase S11 family
B7L39_RS09055	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
B7L39_RS09085	COG0616	signal peptide processing
B7L39_RS09090	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
B7L39_RS09100	COG0573	inorganic phosphate transmembrane transporter activity
B7L39_RS09105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
B7L39_RS09110	COG1113	amino acid transport
B7L39_RS09115	COG3961	Belongs to the TPP enzyme family
B7L39_RS09120	COG1522	sequence-specific DNA binding
B7L39_RS09130	COG0076	glutamate decarboxylase activity
B7L39_RS09135	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7L39_RS09145	COG1309	transcriptional regulator
B7L39_RS09160	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L39_RS09195	COG0352	thiamine-phosphate diphosphorylase activity
B7L39_RS09220	COG0612	Peptidase, M16
B7L39_RS09230	COG1823	symporter activity
B7L39_RS09235	COG0583	DNA-binding transcription factor activity
B7L39_RS09240	COG0477	Major facilitator Superfamily
B7L39_RS09260	COG1187	pseudouridine synthase activity
B7L39_RS09275	COG1686	Belongs to the peptidase S11 family
B7L39_RS09280	COG1252	NADH dehydrogenase
B7L39_RS09290	COG0415	Belongs to the DNA photolyase family
B7L39_RS09305	COG1215	transferase activity, transferring glycosyl groups
B7L39_RS09335	COG2070	2-Nitropropane dioxygenase
B7L39_RS09400	COG0556	nucleotide-excision repair
B7L39_RS09420	COG0436	Aminotransferase
B7L39_RS09445	COG4221	oxidoreductase activity
B7L39_RS09455	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
B7L39_RS09460	COG1381	Involved in DNA repair and RecF pathway recombination
B7L39_RS09470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
B7L39_RS09485	COG0681	Belongs to the peptidase S26 family
B7L39_RS09500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
B7L39_RS09520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
B7L39_RS09525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B7L39_RS09530	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
B7L39_RS09540	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
B7L39_RS09545	COG4208	sulfate ABC transporter
B7L39_RS09550	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
B7L39_RS09555	COG0583	DNA-binding transcription factor activity
B7L39_RS09560	COG4625	pathogenesis
B7L39_RS09575	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
B7L39_RS09590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
B7L39_RS09600	COG1056	cytidyltransferase-related domain
B7L39_RS09600	COG1051	belongs to the nudix hydrolase family
B7L39_RS09605	COG1024	Enoyl-CoA hydratase
B7L39_RS09615	COG2814	Major facilitator Superfamily
B7L39_RS09620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B7L39_RS09620	COG0047	phosphoribosylformylglycinamidine synthase activity
B7L39_RS09640	COG1473	amidohydrolase
B7L39_RS09645	COG0824	Thioesterase
B7L39_RS09665	COG0823	Involved in the tonB-independent uptake of proteins
B7L39_RS09685	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7L39_RS09720	COG0628	permease
B7L39_RS09730	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
B7L39_RS09735	COG0596	Alpha beta hydrolase
B7L39_RS09740	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B7L39_RS09740	COG0616	signal peptide processing
B7L39_RS09750	COG0658	competence protein
B7L39_RS09750	COG2333	competence protein COMEC
B7L39_RS09755	COG1136	(ABC) transporter
B7L39_RS09760	COG4591	ABC-type transport system involved in lipoprotein release permease component
B7L39_RS09790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L39_RS09810	COG0463	Glycosyl transferase, family 2
B7L39_RS09840	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B7L39_RS09845	COG1280	lysine exporter protein (LysE YggA)
B7L39_RS09855	COG0019	diaminopimelate decarboxylase activity
B7L39_RS09865	COG1113	amino acid transport
B7L39_RS09880	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
B7L39_RS09890	COG3339	Conserved Protein
B7L39_RS09895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
B7L39_RS09900	COG0243	molybdopterin cofactor binding
B7L39_RS09905	COG1929	Belongs to the glycerate kinase type-1 family
B7L39_RS09920	COG0778	Nitroreductase
B7L39_RS09945	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L39_RS09960	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B7L39_RS09985	COG0741	lytic transglycosylase activity
B7L39_RS10005	COG0584	glycerophosphoryl diester phosphodiesterase
B7L39_RS10010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L39_RS10035	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7L39_RS10040	COG1597	lipid kinase activity
B7L39_RS10055	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
B7L39_RS10060	COG0477	Major facilitator Superfamily
B7L39_RS10110	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
B7L39_RS10115	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B7L39_RS10145	COG0505	Belongs to the CarA family
B7L39_RS10165	COG0589	response to stress
B7L39_RS10180	COG2843	Capsule synthesis protein
B7L39_RS10210	COG2321	neutral zinc metallopeptidase
B7L39_RS10215	COG2354	Protein conserved in bacteria
B7L39_RS10235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B7L39_RS10255	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
B7L39_RS10260	COG1053	succinate dehydrogenase
B7L39_RS10265	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
B7L39_RS10270	COG2009	succinate dehydrogenase
B7L39_RS10310	COG2921	Belongs to the UPF0250 family
B7L39_RS10315	COG0321	lipoyl(octanoyl) transferase activity
B7L39_RS10330	COG0531	amino acid
B7L39_RS10340	COG1733	regulation of RNA biosynthetic process
B7L39_RS10345	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B7L39_RS10350	COG1648	precorrin-2 dehydrogenase activity
B7L39_RS10350	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
B7L39_RS10365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
B7L39_RS10395	COG0671	phosphoesterase, PA-phosphatase related
B7L39_RS10400	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L39_RS10410	COG1538	Outer membrane efflux protein
B7L39_RS10415	COG0393	Putative heavy-metal-binding
B7L39_RS10420	COG0393	Putative heavy-metal-binding
B7L39_RS10430	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS10440	COG0525	valine-tRNA ligase activity
B7L39_RS10460	COG0583	DNA-binding transcription factor activity
B7L39_RS10470	COG0004	ammonium transporteR
B7L39_RS10480	COG0642	Histidine kinase
B7L39_RS10485	COG0745	RESPONSE REGULATOR receiver
B7L39_RS10490	COG2194	sulfuric ester hydrolase activity
B7L39_RS10510	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7L39_RS10525	COG2315	Protein conserved in bacteria
B7L39_RS10530	COG0142	geranyltranstransferase activity
B7L39_RS10535	COG2828	Protein conserved in bacteria
B7L39_RS10540	COG1113	amino acid transport
B7L39_RS10560	COG2207	Transcriptional regulator
B7L39_RS10585	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L39_RS10595	COG0560	Phosphoserine phosphatase
B7L39_RS10605	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L39_RS10610	COG1530	ribonuclease E activity
B7L39_RS10615	COG0424	maF-like protein
B7L39_RS10620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
B7L39_RS10625	COG1792	Involved in formation and maintenance of cell shape
B7L39_RS10630	COG1077	Cell shape determining protein MreB Mrl
B7L39_RS10635	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7L39_RS10645	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
B7L39_RS10675	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
B7L39_RS10680	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B7L39_RS10685	COG1752	Esterase of the alpha-beta hydrolase superfamily
B7L39_RS10690	COG1115	amino acid carrier protein
B7L39_RS10705	COG2814	Major facilitator Superfamily
B7L39_RS10710	COG1289	transmembrane transporter activity
B7L39_RS10720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
B7L39_RS10760	COG1376	ErfK ybiS ycfS ynhG family protein
B7L39_RS10765	COG2832	Protein of unknown function (DUF454)
B7L39_RS10775	COG5510	response to toxic substance
B7L39_RS10795	COG0840	transmembrane signaling receptor activity
B7L39_RS10835	COG3422	double-strand break repair
B7L39_RS10840	COG2824	Alkylphosphonate utilization operon protein PhnA
B7L39_RS10845	COG3189	MarR family transcriptional regulator
B7L39_RS10855	COG0354	folic acid binding
B7L39_RS10860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L39_RS10870	COG0679	Auxin Efflux Carrier
B7L39_RS10875	COG1902	pentaerythritol trinitrate reductase activity
B7L39_RS10880	COG4772	TonB-dependent receptor
B7L39_RS10890	COG4772	TonB-dependent receptor
B7L39_RS10895	COG2094	Belongs to the DNA glycosylase MPG family
B7L39_RS10920	COG1217	gtp-binding protein TYPA
B7L39_RS10925	COG2233	PERMEase
B7L39_RS10935	COG0833	amino acid
B7L39_RS10940	COG1690	Belongs to the RtcB family
B7L39_RS10950	COG2885	chlorophyll binding
B7L39_RS10950	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
B7L39_RS10960	COG0183	Belongs to the thiolase family
B7L39_RS10980	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
B7L39_RS11000	COG2207	Transcriptional regulator
B7L39_RS11005	COG0183	Belongs to the thiolase family
B7L39_RS11040	COG1272	protein, Hemolysin III
B7L39_RS11045	COG0477	Major facilitator Superfamily
B7L39_RS11060	COG0450	alkyl hydroperoxide reductase
B7L39_RS11080	COG0285	dihydrofolate synthase activity
B7L39_RS11130	COG2096	Adenosyltransferase
B7L39_RS11150	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
B7L39_RS11155	COG0745	RESPONSE REGULATOR receiver
B7L39_RS11160	COG2205	protein histidine kinase activity
B7L39_RS11170	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS11175	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS11180	COG0583	DNA-binding transcription factor activity
B7L39_RS11185	COG0625	glutathione transferase activity
B7L39_RS11250	COG0438	transferase activity, transferring glycosyl groups
B7L39_RS11255	COG0463	Glycosyl transferase, family 2
B7L39_RS11260	COG0726	polysaccharide deacetylase
B7L39_RS11280	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
B7L39_RS11285	COG2205	protein histidine kinase activity
B7L39_RS11330	COG1862	Preprotein translocase
B7L39_RS11340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
B7L39_RS11345	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
B7L39_RS11355	COG3781	membrane
B7L39_RS11360	COG0613	PHP domain protein
B7L39_RS11370	COG2350	Protein conserved in bacteria
B7L39_RS11400	COG1607	acyl-coa hydrolase
B7L39_RS11460	COG2199	diguanylate cyclase activity
B7L39_RS11470	COG1408	metallophosphoesterase
B7L39_RS11475	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
B7L39_RS11485	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B7L39_RS11505	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
B7L39_RS11510	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
B7L39_RS11515	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
B7L39_RS11525	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
B7L39_RS11535	COG2969	positive regulation of protein catabolic process
B7L39_RS11555	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS11560	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B7L39_RS11580	COG1309	transcriptional regulator
B7L39_RS11585	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS11630	COG1183	phosphatidylcholine synthase activity
B7L39_RS11635	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
B7L39_RS11665	COG1196	nuclear chromosome segregation
B7L39_RS11665	COG0739	heme binding
B7L39_RS11665	COG0741	lytic transglycosylase activity
B7L39_RS11675	COG1702	phosphate starvation-inducible protein PhoH
B7L39_RS11710	COG1295	ribonuclease BN
B7L39_RS11715	COG0697	spore germination
B7L39_RS11720	COG2169	Transcriptional regulator
B7L39_RS11725	COG0179	Fumarylacetoacetate (FAA) hydrolase
B7L39_RS11770	COG0557	exoribonuclease II activity
B7L39_RS11775	COG0339	signal peptide processing
B7L39_RS11780	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
B7L39_RS11810	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
B7L39_RS11815	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS11970	COG0626	cystathionine gamma-synthase activity
B7L39_RS11975	COG0433	COG0433 Predicted ATPase
B7L39_RS11980	COG1017	nitric oxide dioxygenase activity
B7L39_RS11980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
B7L39_RS11985	COG1959	2 iron, 2 sulfur cluster binding
B7L39_RS12000	COG1301	dicarboxylic acid transport
B7L39_RS12005	COG1946	Acyl-CoA thioesterase
B7L39_RS12025	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
B7L39_RS12030	COG1040	competence protein
B7L39_RS12035	COG0494	nUDIX hydrolase
B7L39_RS12045	COG0598	Magnesium transport protein CorA
B7L39_RS12055	COG2854	intermembrane phospholipid transfer
B7L39_RS12065	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
B7L39_RS12070	COG1127	ABC transporter
B7L39_RS12075	COG0513	Belongs to the DEAD box helicase family
B7L39_RS12095	COG0408	coproporphyrinogen oxidase activity
B7L39_RS12110	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS12120	COG1983	PspC domain protein
B7L39_RS12125	COG0517	IMP dehydrogenase activity
B7L39_RS12170	COG0583	DNA-binding transcription factor activity
B7L39_RS12210	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS12220	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
B7L39_RS12225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B7L39_RS12230	COG0833	amino acid
B7L39_RS12260	COG1192	Involved in chromosome partitioning
B7L39_RS12265	COG0628	permease
B7L39_RS12275	COG1289	transmembrane transporter activity
B7L39_RS12290	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L39_RS12295	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
B7L39_RS12305	COG0277	FAD linked oxidase domain protein
B7L39_RS12310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B7L39_RS12335	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
B7L39_RS12340	COG5380	lipid catabolic process
B7L39_RS12360	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
B7L39_RS12410	COG0194	GDP metabolic process
B7L39_RS12420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7L39_RS12440	COG3307	-O-antigen
B7L39_RS12460	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
B7L39_RS12465	COG1704	LemA family
B7L39_RS12475	COG0493	'glutamate synthase
B7L39_RS12480	COG0070	glutamate synthase
B7L39_RS12480	COG0067	glutamate synthase
B7L39_RS12480	COG0069	glutamate synthase activity
B7L39_RS12530	COG2226	methyltransferase
B7L39_RS12545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B7L39_RS12550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
B7L39_RS12595	COG0833	amino acid
B7L39_RS12675	COG0488	(ABC) transporter
B7L39_RS12680	COG2873	o-acetylhomoserine
B7L39_RS12685	COG4221	oxidoreductase activity
B7L39_RS12690	COG0659	secondary active sulfate transmembrane transporter activity
B7L39_RS12710	COG0427	acetyl-CoA hydrolase
B7L39_RS12740	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
B7L39_RS12770	COG2329	Antibiotic biosynthesis monooxygenase
B7L39_RS12785	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
B7L39_RS12850	COG2249	NAD(P)H dehydrogenase (quinone) activity
B7L39_RS12860	COG1733	regulation of RNA biosynthetic process
B7L39_RS12895	COG0667	Aldo Keto reductase
B7L39_RS12915	COG0583	DNA-binding transcription factor activity
B7L39_RS12920	COG2814	Major facilitator Superfamily
B7L39_RS12950	COG1335	isochorismatase
B7L39_RS12960	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS12965	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
B7L39_RS12975	COG1113	amino acid transport
B7L39_RS12985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
B7L39_RS13000	COG2814	Major facilitator Superfamily
B7L39_RS13010	COG0351	phosphomethylpyrimidine kinase
B7L39_RS13010	COG0352	thiamine-phosphate diphosphorylase activity
B7L39_RS13010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B7L39_RS13030	COG1309	transcriptional regulator
B7L39_RS13035	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B7L39_RS13055	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
B7L39_RS13065	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B7L39_RS13070	COG3162	membrane
B7L39_RS13075	COG2205	protein histidine kinase activity
B7L39_RS13075	COG0784	Response regulator, receiver
B7L39_RS13075	COG2198	Histidine kinase
B7L39_RS13100	COG3328	transposase activity
B7L39_RS13105	COG1522	sequence-specific DNA binding
B7L39_RS13110	COG1335	isochorismatase
B7L39_RS13115	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7L39_RS13125	COG0668	transmembrane transport
B7L39_RS13130	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B7L39_RS13135	COG1519	Transferase
B7L39_RS13140	COG1902	pentaerythritol trinitrate reductase activity
B7L39_RS13160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
B7L39_RS13185	COG0426	domain, Protein
B7L39_RS13185	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L39_RS13190	COG4774	siderophore transport
B7L39_RS13200	COG4774	siderophore transport
B7L39_RS13205	COG2119	membrane
B7L39_RS13215	COG0508	dehydrogenase complex catalyzes the overall conversion of
B7L39_RS13225	COG4942	peptidase
B7L39_RS13240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B7L39_RS13250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
B7L39_RS13270	COG0189	ligase activity
B7L39_RS13290	COG0708	Exodeoxyribonuclease III
B7L39_RS13295	COG1393	Belongs to the ArsC family
B7L39_RS13310	COG3706	GGDEF domain
B7L39_RS13345	COG2351	hydroxyisourate hydrolase activity
B7L39_RS13350	COG2233	PERMEase
B7L39_RS13360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L39_RS13370	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
B7L39_RS13375	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS13385	COG3150	esterase
B7L39_RS13405	COG0791	NLP P60 protein
B7L39_RS13405	COG1388	LysM domain
B7L39_RS13420	COG2918	glutathione biosynthetic process
B7L39_RS13435	COG2733	membrane
B7L39_RS13440	COG0436	Aminotransferase
B7L39_RS13445	COG0534	Mate efflux family protein
B7L39_RS13550	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
B7L39_RS13555	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
B7L39_RS13565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
B7L39_RS13570	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7L39_RS13585	COG0010	Belongs to the arginase family
B7L39_RS13615	COG2188	Transcriptional regulator
B7L39_RS13625	COG0523	cobalamin synthesis protein
B7L39_RS13635	COG1113	amino acid transport
B7L39_RS13645	COG0625	glutathione transferase activity
B7L39_RS13665	COG1683	Conserved Protein
B7L39_RS13670	COG0534	Mate efflux family protein
B7L39_RS13675	COG0385	Bile acid
B7L39_RS13680	COG1335	isochorismatase
B7L39_RS13685	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L39_RS13705	COG2116	formate transmembrane transporter activity
B7L39_RS13710	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
B7L39_RS13715	COG2133	pyrroloquinoline quinone binding
B7L39_RS13720	COG2983	Belongs to the UPF0260 family
B7L39_RS13725	COG5487	UPF0391 membrane protein
B7L39_RS13740	COG1194	a g-specific adenine glycosylase
B7L39_RS13755	COG2818	Glycosylase
B7L39_RS13760	COG1064	alcohol dehydrogenase
B7L39_RS13765	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L39_RS13775	COG0583	DNA-binding transcription factor activity
B7L39_RS13780	COG0656	L-ascorbic acid biosynthetic process
B7L39_RS13785	COG2814	Major facilitator Superfamily
B7L39_RS13820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L39_RS13835	COG2233	PERMEase
B7L39_RS13840	COG0583	DNA-binding transcription factor activity
B7L39_RS13875	COG0733	neurotransmitter:sodium symporter activity
B7L39_RS13915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
B7L39_RS13920	COG0657	acetylesterase activity
B7L39_RS13940	COG0583	DNA-binding transcription factor activity
B7L39_RS13970	COG2951	lytic endotransglycosylase activity
B7L39_RS13975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B7L39_RS13995	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
B7L39_RS14005	COG0671	phosphoesterase, PA-phosphatase related
B7L39_RS14010	COG0861	Integral membrane protein TerC family
B7L39_RS14020	COG0754	glutathionylspermidine amidase activity
B7L39_RS14030	COG0402	S-adenosylhomocysteine deaminase activity
B7L39_RS14045	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L39_RS14050	COG1230	cation diffusion facilitator family transporter
B7L39_RS14065	COG0706	membrane insertase activity
B7L39_RS14090	COG0592	DNA-directed DNA polymerase activity
B7L39_RS14100	COG0187	DNA topoisomerase II activity
B7L39_RS14110	COG0586	Pfam SNARE associated Golgi protein
B7L39_RS14115	COG0488	(ABC) transporter
B7L39_RS14140	COG0596	Alpha beta hydrolase
B7L39_RS14145	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
B7L39_RS14150	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
B7L39_RS14190	COG1047	Peptidyl-prolyl cis-trans
B7L39_RS14200	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
B7L39_RS14205	COG0196	riboflavin kinase activity
B7L39_RS14215	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
B7L39_RS14220	COG1309	transcriptional regulator
B7L39_RS14225	COG1116	anion transmembrane transporter activity
B7L39_RS14230	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B7L39_RS14235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
B7L39_RS14240	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L39_RS14245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
B7L39_RS14265	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS14270	COG0546	phosphoglycolate phosphatase activity
B7L39_RS14320	COG3023	N-Acetylmuramoyl-L-alanine amidase
B7L39_RS14325	COG0728	peptidoglycan biosynthetic process
B7L39_RS14350	COG1596	polysaccharide export
B7L39_RS14355	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
B7L39_RS14365	COG1215	transferase activity, transferring glycosyl groups
B7L39_RS14370	COG0438	transferase activity, transferring glycosyl groups
B7L39_RS14390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
B7L39_RS14395	COG1210	Utp--glucose-1-phosphate uridylyltransferase
B7L39_RS14410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
B7L39_RS14420	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7L39_RS14430	COG2186	Transcriptional regulator
B7L39_RS14440	COG0277	FAD linked oxidase domain protein
B7L39_RS14445	COG1448	Aminotransferase
B7L39_RS14450	COG1802	Transcriptional regulator
B7L39_RS14465	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
B7L39_RS14540	COG0564	pseudouridine synthase activity
B7L39_RS14580	COG0251	oxidation-reduction process
B7L39_RS14590	COG1113	amino acid transport
B7L39_RS14595	COG1113	amino acid transport
B7L39_RS14615	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
B7L39_RS14620	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS14625	COG1024	Enoyl-CoA hydratase
B7L39_RS14630	COG1024	Enoyl-CoA hydratase
B7L39_RS14635	COG0477	Major facilitator Superfamily
B7L39_RS14640	COG3916	Acyl-homoserine-lactone synthase
B7L39_RS14650	COG2197	response regulator
B7L39_RS14660	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS14665	COG3321	synthase
B7L39_RS14665	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7L39_RS14665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
B7L39_RS14665	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
B7L39_RS14675	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
B7L39_RS14690	COG2267	carboxylic ester hydrolase activity
B7L39_RS14710	COG0271	Belongs to the BolA IbaG family
B7L39_RS14720	COG1192	Involved in chromosome partitioning
B7L39_RS14735	COG0586	Pfam SNARE associated Golgi protein
B7L39_RS14740	COG2259	Doxx family
B7L39_RS14745	COG4399	Belongs to the UPF0754 family
B7L39_RS14750	COG0519	Catalyzes the synthesis of GMP from XMP
B7L39_RS14750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
B7L39_RS14795	COG0281	malic enzyme
B7L39_RS14805	COG2837	iron assimilation
B7L39_RS14810	COG1280	lysine exporter protein (LysE YggA)
B7L39_RS14815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B7L39_RS14820	COG1121	(ABC) transporter
B7L39_RS14885	COG0386	Belongs to the glutathione peroxidase family
B7L39_RS14900	COG1309	transcriptional regulator
B7L39_RS14905	COG0697	spore germination
B7L39_RS14915	COG0758	DNA mediated transformation
B7L39_RS14950	COG1309	transcriptional regulator
B7L39_RS14985	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
B7L39_RS14995	COG0655	NAD(P)H dehydrogenase (quinone) activity
B7L39_RS15030	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B7L39_RS15050	COG1253	flavin adenine dinucleotide binding
B7L39_RS15060	COG2860	membrane
B7L39_RS15065	COG0477	Major facilitator Superfamily
B7L39_RS15075	COG0318	PFAM AMP-dependent synthetase and ligase
B7L39_RS15090	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B7L39_RS15105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B7L39_RS15115	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B7L39_RS15120	COG0606	chelatase, subunit chli
B7L39_RS15160	COG0589	response to stress
B7L39_RS15165	COG0659	secondary active sulfate transmembrane transporter activity
B7L39_RS15180	COG1061	Type III restriction enzyme res subunit
B7L39_RS15225	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
B7L39_RS15270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7L39_RS15315	COG0589	response to stress
B7L39_RS15320	COG0659	secondary active sulfate transmembrane transporter activity
B7L39_RS15335	COG1061	Type III restriction enzyme res subunit
B7L39_RS15405	COG0606	chelatase, subunit chli
B7L39_RS15415	COG0347	Belongs to the P(II) protein family
B7L39_RS15420	COG0004	ammonium transporteR
B7L39_RS15430	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7L39_RS15430	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
B7L39_RS15470	COG0795	lipopolysaccharide-transporting ATPase activity
B7L39_RS15475	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
B7L39_RS15480	COG0793	Belongs to the peptidase S41A family
B7L39_RS15495	COG2197	response regulator
B7L39_RS15505	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
B7L39_RS15515	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
B7L39_RS15520	COG4974	Belongs to the 'phage' integrase family
B7L39_RS15545	COG0772	Belongs to the SEDS family
B7L39_RS15550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
B7L39_RS15555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
B7L39_RS15560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
B7L39_RS15585	COG0697	spore germination
B7L39_RS15590	COG1538	Outer membrane efflux protein
B7L39_RS15610	COG3275	phosphorelay sensor kinase activity
B7L39_RS15620	COG0181	hydroxymethylbilane synthase activity
B7L39_RS15665	COG1716	ATPase activity
B7L39_RS15670	COG0546	phosphoglycolate phosphatase activity
B7L39_RS15765	COG0596	Alpha beta hydrolase
B7L39_RS15770	COG2056	Na+-H+ antiporter family
B7L39_RS15785	COG0326	Molecular chaperone. Has ATPase activity
B7L39_RS15800	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
B7L39_RS15865	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B7L39_RS15870	COG2169	Transcriptional regulator
B7L39_RS15870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7L39_RS15900	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
B7L39_RS15910	COG0497	DNA recombination
B7L39_RS15925	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B7L39_RS15935	COG0237	dephospho-CoA kinase activity
B7L39_RS15985	COG0195	Participates in both transcription termination and antitermination
B7L39_RS16000	COG1320	monovalent cation:proton antiporter activity
B7L39_RS16005	COG2212	antiporter activity
B7L39_RS16010	COG1863	multisubunit Na H antiporter MnhE subunit
B7L39_RS16015	COG0651	ATP synthesis coupled electron transport
B7L39_RS16020	COG1006	Multisubunit Na H antiporter MnhC subunit
B7L39_RS16025	COG2111	Na H antiporter
B7L39_RS16025	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7L39_RS16040	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
B7L39_RS16045	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
B7L39_RS16060	COG2226	methyltransferase
B7L39_RS16080	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
B7L39_RS16085	COG1074	ATP-dependent DNA helicase activity
B7L39_RS16090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B7L39_RS16095	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
B7L39_RS16110	COG0598	Magnesium transport protein CorA
B7L39_RS16115	COG0789	Transcriptional regulator
B7L39_RS16120	COG0484	heat shock protein binding
B7L39_RS16130	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
B7L39_RS16135	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7L39_RS16135	COG0475	glutathione-regulated potassium exporter activity
B7L39_RS16140	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
B7L39_RS16170	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7L39_RS16180	COG4535	Mg2 and Co2 transporter CorC
B7L39_RS16185	COG0425	Belongs to the sulfur carrier protein TusA family
B7L39_RS16190	COG0644	oxidoreductase
B7L39_RS16190	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
B7L39_RS16200	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
B7L39_RS16215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
B7L39_RS16220	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
B7L39_RS16255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
B7L39_RS16270	COG0534	Mate efflux family protein
B7L39_RS16280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
B7L39_RS16285	COG4221	oxidoreductase activity
B7L39_RS16290	COG0583	DNA-binding transcription factor activity
B7L39_RS16305	COG0318	PFAM AMP-dependent synthetase and ligase
B7L39_RS16310	COG1530	ribonuclease E activity
B7L39_RS16325	COG0546	phosphoglycolate phosphatase activity
B7L39_RS16330	COG2378	regulation of single-species biofilm formation
B7L39_RS16335	COG0625	glutathione transferase activity
B7L39_RS16345	COG0583	DNA-binding transcription factor activity
B7L39_RS16410	COG0473	3-isopropylmalate dehydrogenase activity
B7L39_RS16465	COG1301	dicarboxylic acid transport
B7L39_RS16475	COG1560	Kdo2-lipid A biosynthetic process
B7L39_RS16480	COG1280	lysine exporter protein (LysE YggA)
B7L39_RS16485	COG0488	(ABC) transporter
B7L39_RS16490	COG2900	Belongs to the SlyX family
B7L39_RS16500	COG1733	regulation of RNA biosynthetic process
B7L39_RS16525	COG0210	DNA helicase
B7L39_RS16530	COG0724	RNA recognition motif
B7L39_RS16550	COG4651	solute:proton antiporter activity
B7L39_RS16550	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
B7L39_RS16575	COG0788	formyltetrahydrofolate deformylase activity
B7L39_RS16675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7L39_RS16675	COG2813	Specifically methylates the guanine in position
B7L39_RS16685	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
B7L39_RS16705	COG0740	serine-type endopeptidase activity
B7L39_RS16725	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
B7L39_RS16725	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
B7L39_RS16730	COG0280	phosphate acetyltransferase
B7L39_RS16730	COG0857	belongs to the CobB CobQ family
B7L39_RS16735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B7L39_RS16745	COG0800	Aldolase
B7L39_RS16755	COG3265	gluconokinase activity
B7L39_RS16760	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS16770	COG2267	carboxylic ester hydrolase activity
B7L39_RS16785	COG0793	Belongs to the peptidase S41A family
B7L39_RS16820	COG1426	Protein conserved in bacteria
B7L39_RS16865	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
B7L39_RS16875	COG0318	PFAM AMP-dependent synthetase and ligase
B7L39_RS16890	COG2986	histidine ammonia-lyase
B7L39_RS16930	COG1028	Short-chain dehydrogenase reductase Sdr
B7L39_RS16935	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
B7L39_RS16955	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
B7L39_RS16965	COG1162	GTPase activity
B7L39_RS16970	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
B7L39_RS16985	COG1538	Outer membrane efflux protein
B7L39_RS16990	COG1136	(ABC) transporter
B7L39_RS16990	COG0577	efflux transmembrane transporter activity
B7L39_RS16995	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
B7L39_RS17025	COG0028	Belongs to the TPP enzyme family
B7L39_RS17030	COG0440	acetolactate synthase activity
B7L39_RS17065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
B7L39_RS17080	COG0084	hydrolase, TatD family'
B7L39_RS17095	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
B7L39_RS17100	COG0583	DNA-binding transcription factor activity
B7L39_RS17110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7L39_RS17115	COG2814	Major facilitator Superfamily
B7L39_RS17125	COG0697	spore germination
B7L39_RS17155	COG3622	Belongs to the hyi family
B7L39_RS17160	COG2084	Dehydrogenase
B7L39_RS17165	COG1024	Enoyl-CoA hydratase
B7L39_RS17170	COG0784	Response regulator, receiver
B7L39_RS17170	COG2205	protein histidine kinase activity
B7L39_RS17170	COG5002	protein histidine kinase activity
B7L39_RS17190	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B7L39_RS17200	COG3956	TIGRFAM MazG family protein
B7L39_RS17205	COG1555	photosystem II stabilization
B7L39_RS17210	COG0617	tRNA 3'-terminal CCA addition
B7L39_RS17215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
B7L39_RS17235	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
B7L39_RS17240	COG3028	Belongs to the UPF0307 family
B7L39_RS17245	COG0318	PFAM AMP-dependent synthetase and ligase
B7L39_RS17265	COG0625	glutathione transferase activity
B7L39_RS17270	COG1238	metal cluster binding
B7L39_RS17315	COG0072	phenylalanine-tRNA ligase activity
B7L39_RS17340	COG0248	Ppx GppA phosphatase
B7L39_RS17350	COG0037	tRNA processing
B7L39_RS17390	COG1764	response to oxidative stress
B7L39_RS17395	COG1846	Transcriptional regulator
B7L39_RS17405	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7L39_RS17465	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B7L39_RS17470	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
B7L39_RS17475	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
B7L39_RS17485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
B7L39_RS17540	COG1214	PFAM Peptidase M22, glycoprotease
B7L39_RS17565	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B7L39_RS17570	COG0561	phosphatase activity
B7L39_RS17580	COG2132	Multicopper oxidase
B7L39_RS17585	COG3667	copper resistance
B7L39_RS17600	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B7L39_RS17605	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
B7L39_RS17610	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B7L39_RS17640	COG1063	alcohol dehydrogenase
B7L39_RS17645	COG0583	DNA-binding transcription factor activity
B7L39_RS17650	COG1960	acyl-CoA dehydrogenase activity
B7L39_RS17655	COG2814	Major facilitator Superfamily
B7L39_RS17660	COG1804	L-carnitine dehydratase bile acid-inducible protein F
B7L39_RS17670	COG1053	succinate dehydrogenase
B7L39_RS17675	COG0583	DNA-binding transcription factor activity
B7L39_RS17695	COG0583	DNA-binding transcription factor activity
B7L39_RS17725	COG0583	DNA-binding transcription factor activity
B7L39_RS17740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
B7L39_RS17770	COG0384	phenazine biosynthesis protein PhzF
B7L39_RS17790	COG4993	Dehydrogenase
B7L39_RS17860	COG2205	protein histidine kinase activity
B7L39_RS17870	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B7L39_RS17890	COG0745	RESPONSE REGULATOR receiver
B7L39_RS17930	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
B7L39_RS17960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
B7L39_RS17965	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
B7L39_RS17985	COG0583	DNA-binding transcription factor activity
B7L39_RS18005	COG0668	transmembrane transport
B7L39_RS18015	COG2515	1-aminocyclopropane-1-carboxylate deaminase
B7L39_RS18045	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7L39_RS18045	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
B7L39_RS18055	COG0489	protein tyrosine kinase activity
B7L39_RS18110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
B7L39_RS18120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
B7L39_RS18135	COG0730	response to heat
B7L39_RS18145	COG1196	nuclear chromosome segregation
B7L39_RS18165	COG2223	nitrite transmembrane transporter activity
B7L39_RS18170	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
B7L39_RS18175	COG1877	trehalose-phosphatase activity
B7L39_RS18180	COG0596	Alpha beta hydrolase
B7L39_RS18180	COG2226	methyltransferase
B7L39_RS18180	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
B7L39_RS18195	COG4106	trans-aconitate 2-methyltransferase activity
B7L39_RS18210	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B7L39_RS18215	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
B7L39_RS18220	COG0009	L-threonylcarbamoyladenylate synthase
B7L39_RS18225	COG3101	peptidyl-lysine hydroxylation
B7L39_RS18230	COG1399	metal-binding, possibly nucleic acid-binding protein
B7L39_RS18255	COG1652	LysM domain
B7L39_RS18260	COG0351	phosphomethylpyrimidine kinase
B7L39_RS18260	COG0352	thiamine-phosphate diphosphorylase activity
B7L39_RS18260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B7L39_RS18270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
B7L39_RS18300	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
B7L39_RS18330	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
B7L39_RS18345	COG0358	DNA primase activity
B7L39_RS18355	COG0564	pseudouridine synthase activity
B7L39_RS18380	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
B7L39_RS18400	COG0583	DNA-binding transcription factor activity
B7L39_RS18405	COG0473	3-isopropylmalate dehydrogenase activity
B7L39_RS18415	COG0657	acetylesterase activity
B7L39_RS18425	COG1012	belongs to the aldehyde dehydrogenase family
B7L39_RS18445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B7L39_RS18445	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
B7L39_RS18460	COG1981	membrane
B7L39_RS18505	COG0456	acetyltransferase
B7L39_RS18515	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
B7L39_RS18520	COG0492	ferredoxin-NADP+ reductase activity
B7L39_RS18525	COG1674	ftsk spoiiie
B7L39_RS18525	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
B7L39_RS18530	COG1280	lysine exporter protein (LysE YggA)
B7L39_RS18550	COG2894	cell division
B7L39_RS18565	COG0204	Acyl-transferase
B7L39_RS18570	COG2885	chlorophyll binding
B7L39_RS18575	COG0210	DNA helicase
B7L39_RS18585	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
B7L39_RS18600	COG0121	glutamine amidotransferase
B7L39_RS18625	COG1525	nuclease
B7L39_RS18695	COG1475	DNA binding
B7L39_RS18715	COG3853	Toxic anion resistance protein (TelA)
B7L39_RS18930	COG0741	lytic transglycosylase activity
B7L39_RS18965	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process