locus-tag	class	description
FDE89_RS00010	COG0542	response to heat
FDE89_RS00045	COG2885	chlorophyll binding
FDE89_RS00055	COG0625	glutathione transferase activity
FDE89_RS00060	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDE89_RS00080	COG3634	alkyl hydroperoxide reductase activity
FDE89_RS00090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FDE89_RS00100	COG0450	alkyl hydroperoxide reductase
FDE89_RS00105	COG1643	Atp-dependent helicase
FDE89_RS00120	COG2814	Major facilitator Superfamily
FDE89_RS00125	COG3135	benzoate transporter
FDE89_RS00130	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS00135	COG0543	2 iron, 2 sulfur cluster binding
FDE89_RS00135	COG0633	Ferredoxin
FDE89_RS00140	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDE89_RS00145	COG4638	Rieske (2fe-2S)
FDE89_RS00150	COG0583	DNA-binding transcription factor activity
FDE89_RS00205	COG1570	exodeoxyribonuclease VII activity
FDE89_RS00240	COG1280	lysine exporter protein (LysE YggA)
FDE89_RS00245	COG1278	Cold shock
FDE89_RS00285	COG2814	Major facilitator Superfamily
FDE89_RS00325	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDE89_RS00325	COG0517	IMP dehydrogenase activity
FDE89_RS00330	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FDE89_RS00340	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FDE89_RS00345	COG1137	ATPase activity
FDE89_RS00350	COG1538	Outer membrane efflux protein
FDE89_RS00380	COG4122	O-methyltransferase activity
FDE89_RS00390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FDE89_RS00405	COG1522	sequence-specific DNA binding
FDE89_RS00410	COG5006	permease, DMT superfamily
FDE89_RS00420	COG1560	Kdo2-lipid A biosynthetic process
FDE89_RS00435	COG2814	Major facilitator Superfamily
FDE89_RS00455	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDE89_RS00510	COG0583	DNA-binding transcription factor activity
FDE89_RS00515	COG1914	H( )-stimulated, divalent metal cation uptake system
FDE89_RS00535	COG4770	biotin carboxylase activity
FDE89_RS00540	COG0038	chloride channel
FDE89_RS00565	COG1309	transcriptional regulator
FDE89_RS00590	COG0439	Biotin carboxylase
FDE89_RS00595	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDE89_RS00615	COG0864	Transcriptional regulator
FDE89_RS00625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDE89_RS00630	COG1116	anion transmembrane transporter activity
FDE89_RS00760	COG0590	tRNA wobble adenosine to inosine editing
FDE89_RS00765	COG2807	transmembrane transport
FDE89_RS00780	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FDE89_RS00790	COG0789	Transcriptional regulator
FDE89_RS00805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDE89_RS00825	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDE89_RS00835	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDE89_RS00850	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS00855	COG0531	amino acid
FDE89_RS00860	COG1760	l-serine dehydratase
FDE89_RS00865	COG2030	dehydratase
FDE89_RS00865	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS00870	COG3396	Phenylacetate-CoA oxygenase
FDE89_RS00875	COG3460	Phenylacetate-CoA oxygenase
FDE89_RS00880	COG3396	Phenylacetate-CoA oxygenase
FDE89_RS00885	COG2151	metal-sulfur cluster biosynthetic enzyme
FDE89_RS00890	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDE89_RS00895	COG1024	Enoyl-CoA hydratase
FDE89_RS00900	COG1024	Enoyl-CoA hydratase
FDE89_RS00905	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDE89_RS00910	COG0183	Belongs to the thiolase family
FDE89_RS00915	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FDE89_RS00920	COG3327	negative regulation of DNA-templated transcription, initiation
FDE89_RS00930	COG2050	protein possibly involved in aromatic compounds catabolism
FDE89_RS00970	COG0753	catalase activity
FDE89_RS00975	COG3038	cytochrome b561
FDE89_RS00995	COG2267	carboxylic ester hydrolase activity
FDE89_RS01000	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDE89_RS01005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDE89_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS01020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDE89_RS01030	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS01035	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDE89_RS01040	COG0583	DNA-binding transcription factor activity
FDE89_RS01050	COG1414	Transcriptional regulator
FDE89_RS01065	COG1840	ABC-type Fe3 transport system, periplasmic component
FDE89_RS01070	COG3842	ATPase activity
FDE89_RS01085	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FDE89_RS01090	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDE89_RS01095	COG2814	Major facilitator Superfamily
FDE89_RS01100	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS01115	COG1024	Enoyl-CoA hydratase
FDE89_RS01125	COG2814	Major facilitator Superfamily
FDE89_RS01135	COG0183	Belongs to the thiolase family
FDE89_RS01140	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDE89_RS01145	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS01150	COG1024	Enoyl-CoA hydratase
FDE89_RS01155	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS01160	COG2814	Major facilitator Superfamily
FDE89_RS01165	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDE89_RS01170	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDE89_RS01180	COG2814	Major facilitator Superfamily
FDE89_RS01190	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS01205	COG0583	DNA-binding transcription factor activity
FDE89_RS01215	COG4770	biotin carboxylase activity
FDE89_RS01220	COG1024	Enoyl-CoA hydratase
FDE89_RS01225	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDE89_RS01230	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS01235	COG1309	transcriptional regulator
FDE89_RS01240	COG0318	PFAM AMP-dependent synthetase and ligase
FDE89_RS01260	COG0583	DNA-binding transcription factor activity
FDE89_RS01305	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS01325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDE89_RS01345	COG0784	Response regulator, receiver
FDE89_RS01345	COG2205	protein histidine kinase activity
FDE89_RS01365	COG0765	amino acid transport
FDE89_RS01370	COG0765	amino acid transport
FDE89_RS01375	COG1126	abc transporter atp-binding protein
FDE89_RS01380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDE89_RS01385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDE89_RS01400	COG1280	lysine exporter protein (LysE YggA)
FDE89_RS01405	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FDE89_RS01410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDE89_RS01415	COG1045	serine acetyltransferase
FDE89_RS01430	COG0583	DNA-binding transcription factor activity
FDE89_RS01435	COG0625	glutathione transferase activity
FDE89_RS01440	COG0625	glutathione transferase activity
FDE89_RS01445	COG0583	DNA-binding transcription factor activity
FDE89_RS01455	COG1346	cytolysis
FDE89_RS01475	COG2814	Major facilitator Superfamily
FDE89_RS01485	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FDE89_RS01490	COG3052	prosthetic group binding
FDE89_RS01510	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FDE89_RS01530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDE89_RS01540	COG1294	oxidase, subunit
FDE89_RS01545	COG1271	oxidase subunit
FDE89_RS01570	COG0477	Major facilitator Superfamily
FDE89_RS01580	COG4521	taurine ABC transporter
FDE89_RS01585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FDE89_RS01590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDE89_RS01595	COG2175	clavaminate synthase activity
FDE89_RS01605	COG1953	Uracil, thiamine, allantoin
FDE89_RS01615	COG0583	DNA-binding transcription factor activity
FDE89_RS01625	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FDE89_RS01640	COG0640	Transcriptional regulator
FDE89_RS01645	COG0798	PFAM Bile acid sodium symporter
FDE89_RS01650	COG0583	DNA-binding transcription factor activity
FDE89_RS01665	COG3634	alkyl hydroperoxide reductase activity
FDE89_RS01705	COG0436	Aminotransferase
FDE89_RS01715	COG0386	Belongs to the glutathione peroxidase family
FDE89_RS01755	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDE89_RS01780	COG0012	GTP binding
FDE89_RS01785	COG2011	ABC-type metal ion transport system permease component
FDE89_RS01790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDE89_RS01800	COG1464	Belongs to the NlpA lipoprotein family
FDE89_RS01830	COG0765	amino acid transport
FDE89_RS01835	COG0765	amino acid transport
FDE89_RS01840	COG1126	abc transporter atp-binding protein
FDE89_RS01850	COG1522	sequence-specific DNA binding
FDE89_RS01865	COG1309	transcriptional regulator
FDE89_RS01885	COG0583	DNA-binding transcription factor activity
FDE89_RS01895	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDE89_RS01905	COG0697	spore germination
FDE89_RS01935	COG3121	Chaperone
FDE89_RS01940	COG3539	Fimbrial protein
FDE89_RS01965	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FDE89_RS01965	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FDE89_RS02010	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDE89_RS02020	COG2353	YceI-like domain
FDE89_RS02030	COG3698	Phosphodiester glycosidase
FDE89_RS02045	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FDE89_RS02050	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDE89_RS02050	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDE89_RS02050	COG0506	proline dehydrogenase activity
FDE89_RS02060	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDE89_RS02065	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDE89_RS02085	COG1132	(ABC) transporter
FDE89_RS02090	COG3122	Protein conserved in bacteria
FDE89_RS02095	COG3619	membrane
FDE89_RS02105	COG0640	Transcriptional regulator
FDE89_RS02115	COG2850	peptidyl-arginine hydroxylation
FDE89_RS02120	COG0424	maF-like protein
FDE89_RS02140	COG0191	fructose-bisphosphate aldolase activity
FDE89_RS02145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDE89_RS02160	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDE89_RS02170	COG1192	Involved in chromosome partitioning
FDE89_RS02175	COG1475	DNA binding
FDE89_RS02180	COG0811	peptide transport
FDE89_RS02190	COG1132	(ABC) transporter
FDE89_RS02195	COG1663	tetraacyldisaccharide 4'-kinase activity
FDE89_RS02215	COG0084	hydrolase, TatD family'
FDE89_RS02280	COG0776	regulation of translation
FDE89_RS02310	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FDE89_RS02315	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FDE89_RS02365	COG0339	signal peptide processing
FDE89_RS02375	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDE89_RS02410	COG0702	epimerase
FDE89_RS02415	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDE89_RS02435	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FDE89_RS02465	COG0316	Belongs to the HesB IscA family
FDE89_RS02470	COG0822	iron-sulfur transferase activity
FDE89_RS02495	COG0776	regulation of translation
FDE89_RS02500	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDE89_RS02505	COG2207	Transcriptional regulator
FDE89_RS02510	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDE89_RS02515	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS02520	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS02535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDE89_RS02555	COG4264	IucA IucC family
FDE89_RS02560	COG4264	IucA IucC family
FDE89_RS02620	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
FDE89_RS02640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDE89_RS02645	COG0730	response to heat
FDE89_RS02665	COG4773	Receptor
FDE89_RS02670	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDE89_RS02690	COG0842	Transport permease protein
FDE89_RS02695	COG0842	Transport permease protein
FDE89_RS02755	COG2226	methyltransferase
FDE89_RS02780	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDE89_RS02815	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDE89_RS02825	COG0133	tryptophan synthase activity
FDE89_RS02840	COG3706	GGDEF domain
FDE89_RS02855	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDE89_RS02860	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FDE89_RS02865	COG0022	dehydrogenase e1 component
FDE89_RS02870	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDE89_RS02875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDE89_RS02885	COG1063	alcohol dehydrogenase
FDE89_RS02890	COG3781	membrane
FDE89_RS02900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDE89_RS02900	COG3453	Protein conserved in bacteria
FDE89_RS02910	COG0730	response to heat
FDE89_RS02925	COG3708	Transcriptional regulator
FDE89_RS02925	COG2207	Transcriptional regulator
FDE89_RS02930	COG1733	regulation of RNA biosynthetic process
FDE89_RS02935	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDE89_RS02945	COG2188	Transcriptional regulator
FDE89_RS02960	COG4521	taurine ABC transporter
FDE89_RS02965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDE89_RS02985	COG0477	Major facilitator Superfamily
FDE89_RS02995	COG1027	Aspartate ammonia-lyase
FDE89_RS03010	COG0583	DNA-binding transcription factor activity
FDE89_RS03015	COG0583	DNA-binding transcription factor activity
FDE89_RS03020	COG0183	Belongs to the thiolase family
FDE89_RS03025	COG2031	fatty acid transporter
FDE89_RS03030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDE89_RS03040	COG0583	DNA-binding transcription factor activity
FDE89_RS03050	COG2610	gluconate transmembrane transporter activity
FDE89_RS03055	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS03065	COG2207	Transcriptional regulator
FDE89_RS03080	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS03105	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDE89_RS03105	COG0543	2 iron, 2 sulfur cluster binding
FDE89_RS03110	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDE89_RS03115	COG4638	Rieske (2fe-2S)
FDE89_RS03125	COG0725	ABC transporter, periplasmic molybdate-binding protein
FDE89_RS03130	COG4149	molybdate abc transporter
FDE89_RS03135	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FDE89_RS03140	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS03145	COG1535	isochorismatase
FDE89_RS03145	COG3433	isochorismatase activity
FDE89_RS03210	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDE89_RS03225	COG0753	catalase activity
FDE89_RS03235	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FDE89_RS03265	COG3539	Fimbrial protein
FDE89_RS03285	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDE89_RS03305	COG2072	flavoprotein involved in K transport
FDE89_RS03315	COG1538	Outer membrane efflux protein
FDE89_RS03320	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDE89_RS03325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDE89_RS03330	COG0745	RESPONSE REGULATOR receiver
FDE89_RS03335	COG2205	protein histidine kinase activity
FDE89_RS03345	COG2207	Transcriptional regulator
FDE89_RS03360	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS03415	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FDE89_RS03540	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDE89_RS03560	COG1120	ATPase activity
FDE89_RS03565	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDE89_RS03575	COG1064	alcohol dehydrogenase
FDE89_RS03590	COG2207	Transcriptional regulator
FDE89_RS03595	COG2084	Dehydrogenase
FDE89_RS03610	COG0583	DNA-binding transcription factor activity
FDE89_RS03620	COG0129	dihydroxy-acid dehydratase activity
FDE89_RS03625	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS03640	COG1566	PFAM secretion protein HlyD family protein
FDE89_RS03660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDE89_RS03690	COG0583	DNA-binding transcription factor activity
FDE89_RS03705	COG2188	Transcriptional regulator
FDE89_RS03735	COG3210	domain, Protein
FDE89_RS03740	COG2831	hemolysin activation secretion protein
FDE89_RS03755	COG1473	amidohydrolase
FDE89_RS03765	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDE89_RS03765	COG0475	glutathione-regulated potassium exporter activity
FDE89_RS03780	COG1335	isochorismatase
FDE89_RS03790	COG1309	transcriptional regulator
FDE89_RS03820	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FDE89_RS03830	COG1902	pentaerythritol trinitrate reductase activity
FDE89_RS03830	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDE89_RS03835	COG1846	Transcriptional regulator
FDE89_RS03860	COG0753	catalase activity
FDE89_RS03875	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS03890	COG3162	membrane
FDE89_RS03900	COG3829	transcription factor binding
FDE89_RS03905	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS03910	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS03930	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS03950	COG2186	Transcriptional regulator
FDE89_RS03960	COG0583	DNA-binding transcription factor activity
FDE89_RS03965	COG4948	Mandelate Racemase Muconate Lactonizing
FDE89_RS03970	COG4829	muconolactone delta-isomerase
FDE89_RS03980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDE89_RS03985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDE89_RS03990	COG0183	Belongs to the thiolase family
FDE89_RS03995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDE89_RS04005	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS04035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDE89_RS04045	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS04055	COG4638	Rieske (2fe-2S)
FDE89_RS04075	COG0154	amidase activity
FDE89_RS04085	COG2814	Major facilitator Superfamily
FDE89_RS04110	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS04115	COG0583	DNA-binding transcription factor activity
FDE89_RS04120	COG1414	Transcriptional regulator
FDE89_RS04135	COG2391	methyltransferase activity
FDE89_RS04145	COG4993	Dehydrogenase
FDE89_RS04155	COG3420	alginic acid biosynthetic process
FDE89_RS04160	COG0710	3-dehydroquinate dehydratase activity
FDE89_RS04165	COG3485	protocatechuate 3,4-dioxygenase
FDE89_RS04170	COG3485	protocatechuate 3,4-dioxygenase
FDE89_RS04175	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDE89_RS04180	COG2271	Major facilitator Superfamily
FDE89_RS04185	COG0596	Alpha beta hydrolase
FDE89_RS04190	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FDE89_RS04195	COG0183	Belongs to the thiolase family
FDE89_RS04200	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDE89_RS04205	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDE89_RS04215	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FDE89_RS04220	COG2323	membrane
FDE89_RS04265	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDE89_RS04265	COG1902	pentaerythritol trinitrate reductase activity
FDE89_RS04290	COG0542	response to heat
FDE89_RS04295	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FDE89_RS04325	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDE89_RS04330	COG0569	domain protein
FDE89_RS04350	COG4774	siderophore transport
FDE89_RS04355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDE89_RS04365	COG1585	Membrane protein implicated in regulation of membrane protease activity
FDE89_RS04390	COG1294	oxidase, subunit
FDE89_RS04395	COG4890	Cyd operon protein YbgT
FDE89_RS04410	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDE89_RS04420	COG0552	protein localization to endoplasmic reticulum
FDE89_RS04445	COG0516	GMP reductase activity
FDE89_RS04445	COG0517	IMP dehydrogenase activity
FDE89_RS04450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDE89_RS04455	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FDE89_RS04465	COG0583	DNA-binding transcription factor activity
FDE89_RS04470	COG0024	Methionine aminopeptidase
FDE89_RS04500	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDE89_RS04500	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDE89_RS04505	COG1105	Belongs to the carbohydrate kinase PfkB family
FDE89_RS04510	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDE89_RS04510	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDE89_RS04510	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FDE89_RS04530	COG3300	MHYT domain
FDE89_RS04530	COG5001	Diguanylate cyclase
FDE89_RS04545	COG2135	peptidase activity
FDE89_RS04550	COG0659	secondary active sulfate transmembrane transporter activity
FDE89_RS04565	COG1113	amino acid transport
FDE89_RS04575	COG1522	sequence-specific DNA binding
FDE89_RS04600	COG1011	Hydrolase
FDE89_RS04605	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDE89_RS04615	COG2137	regulation of response to DNA damage stimulus
FDE89_RS04630	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDE89_RS04665	COG0575	Belongs to the CDS family
FDE89_RS04670	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDE89_RS04695	COG3852	Histidine kinase
FDE89_RS04700	COG2204	response regulator
FDE89_RS04760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDE89_RS04765	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FDE89_RS04785	COG0697	spore germination
FDE89_RS04790	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDE89_RS04800	COG0303	'Molybdopterin
FDE89_RS04805	COG0521	Mo-molybdopterin cofactor biosynthetic process
FDE89_RS04805	COG0315	cyclic pyranopterin monophosphate synthase activity
FDE89_RS04820	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FDE89_RS04825	COG0243	molybdopterin cofactor binding
FDE89_RS04835	COG0243	molybdopterin cofactor binding
FDE89_RS04840	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDE89_RS04845	COG2146	nitrite reductase [NAD(P)H] activity
FDE89_RS04845	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDE89_RS04855	COG0745	RESPONSE REGULATOR receiver
FDE89_RS04860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDE89_RS04860	COG1116	anion transmembrane transporter activity
FDE89_RS04875	COG0511	ligase activity, forming carbon-carbon bonds
FDE89_RS04890	COG2814	Major facilitator Superfamily
FDE89_RS04910	COG0069	glutamate synthase activity
FDE89_RS04930	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FDE89_RS04940	COG1454	alcohol dehydrogenase
FDE89_RS04945	COG0824	Thioesterase
FDE89_RS04955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
FDE89_RS04970	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FDE89_RS04975	COG2030	dehydratase
FDE89_RS04985	COG0183	Belongs to the thiolase family
FDE89_RS04995	COG0583	DNA-binding transcription factor activity
FDE89_RS05000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FDE89_RS05010	COG1522	sequence-specific DNA binding
FDE89_RS05015	COG3135	benzoate transporter
FDE89_RS05025	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FDE89_RS05040	COG0589	response to stress
FDE89_RS05045	COG0488	(ABC) transporter
FDE89_RS05065	COG4773	Receptor
FDE89_RS05095	COG0668	transmembrane transport
FDE89_RS05105	COG1309	transcriptional regulator
FDE89_RS05125	COG1605	Chorismate mutase
FDE89_RS05150	COG0308	aminopeptidase N
FDE89_RS05170	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
FDE89_RS05180	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDE89_RS05185	COG1454	alcohol dehydrogenase
FDE89_RS05205	COG0531	amino acid
FDE89_RS05210	COG4303	Ethanolamine ammonia lyase large subunit
FDE89_RS05215	COG4302	ethanolamine ammonia-lyase activity
FDE89_RS05220	COG0519	Catalyzes the synthesis of GMP from XMP
FDE89_RS05220	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDE89_RS05225	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDE89_RS05235	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDE89_RS05250	COG0697	spore germination
FDE89_RS05255	COG1923	regulation of RNA biosynthetic process
FDE89_RS05265	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDE89_RS05270	COG0802	atpase or kinase
FDE89_RS05290	COG1187	pseudouridine synthase activity
FDE89_RS05305	COG0583	DNA-binding transcription factor activity
FDE89_RS05320	COG2814	Major facilitator Superfamily
FDE89_RS05325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDE89_RS05355	COG0729	surface antigen
FDE89_RS05375	COG0174	glutamine synthetase
FDE89_RS05380	COG0745	RESPONSE REGULATOR receiver
FDE89_RS05385	COG2205	protein histidine kinase activity
FDE89_RS05395	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FDE89_RS05400	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FDE89_RS05425	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDE89_RS05430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDE89_RS05435	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS05450	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDE89_RS05455	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDE89_RS05475	COG0583	DNA-binding transcription factor activity
FDE89_RS05495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDE89_RS05505	COG3658	cytochrome
FDE89_RS05510	COG1215	transferase activity, transferring glycosyl groups
FDE89_RS05515	COG0726	polysaccharide deacetylase
FDE89_RS05515	COG1649	PFAM Uncharacterised BCR, COG1649
FDE89_RS05540	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDE89_RS05545	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FDE89_RS05555	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FDE89_RS05580	COG0305	Participates in initiation and elongation during chromosome replication
FDE89_RS05585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDE89_RS05595	COG1305	Transglutaminase-like
FDE89_RS05605	COG2308	Evidence 4 Homologs of previously reported genes of
FDE89_RS05635	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FDE89_RS05640	COG0138	bifunctional purine biosynthesis protein purh
FDE89_RS05645	COG0151	Belongs to the GarS family
FDE89_RS05650	COG1464	Belongs to the NlpA lipoprotein family
FDE89_RS05655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDE89_RS05660	COG2011	ABC-type metal ion transport system permease component
FDE89_RS05665	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDE89_RS05675	COG1301	dicarboxylic acid transport
FDE89_RS05720	COG2433	Pfam Transposase IS66
FDE89_RS05730	COG3173	Aminoglycoside phosphotransferase
FDE89_RS05735	COG0488	(ABC) transporter
FDE89_RS05750	COG0482	sulfurtransferase activity
FDE89_RS05775	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDE89_RS05775	COG3008	intermembrane lipid transfer
FDE89_RS05780	COG2995	paraquat-inducible protein a
FDE89_RS05790	COG2985	domain, Protein
FDE89_RS05820	COG0477	Major facilitator Superfamily
FDE89_RS05870	COG2186	Transcriptional regulator
FDE89_RS05880	COG0786	glutamate:sodium symporter activity
FDE89_RS05910	COG3111	PFAM Bacterial OB fold (BOF) protein
FDE89_RS06010	COG1610	YqeY-like protein
FDE89_RS06015	COG4783	chaperone-mediated protein folding
FDE89_RS06040	COG1286	toxin biosynthetic process
FDE89_RS06070	COG0778	Nitroreductase
FDE89_RS06080	COG0513	Belongs to the DEAD box helicase family
FDE89_RS06100	COG2363	Small membrane protein
FDE89_RS06130	COG1234	tRNA 3'-trailer cleavage
FDE89_RS06135	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDE89_RS06145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FDE89_RS06155	COG2819	hydrolase of the alpha beta superfamily
FDE89_RS06160	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS06165	COG1301	dicarboxylic acid transport
FDE89_RS06175	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FDE89_RS06180	COG3139	Protein of unknown function (DUF1315)
FDE89_RS06185	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FDE89_RS06190	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDE89_RS06200	COG0494	nUDIX hydrolase
FDE89_RS06210	COG0642	Histidine kinase
FDE89_RS06225	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDE89_RS06235	COG1720	tRNA m6t6A37 methyltransferase activity
FDE89_RS06250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDE89_RS06255	COG0826	peptidase U32
FDE89_RS06260	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDE89_RS06270	COG4598	ABC transporter
FDE89_RS06275	COG4160	amino acid transport
FDE89_RS06280	COG4215	(ABC) transporter
FDE89_RS06295	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDE89_RS06340	COG1131	(ABC) transporter
FDE89_RS06345	COG0842	Transport permease protein
FDE89_RS06360	COG0772	Belongs to the SEDS family
FDE89_RS06365	COG2951	lytic endotransglycosylase activity
FDE89_RS06390	COG2207	Transcriptional regulator
FDE89_RS06405	COG0052	Belongs to the universal ribosomal protein uS2 family
FDE89_RS06420	COG2223	nitrite transmembrane transporter activity
FDE89_RS06430	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDE89_RS06435	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDE89_RS06440	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS06455	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FDE89_RS06460	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FDE89_RS06465	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDE89_RS06485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDE89_RS06490	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDE89_RS06495	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FDE89_RS06530	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FDE89_RS06540	COG0174	glutamine synthetase
FDE89_RS06555	COG0512	Glutamine amidotransferase of anthranilate synthase
FDE89_RS06590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FDE89_RS06600	COG0302	gtp cyclohydrolase
FDE89_RS06630	COG3739	integral membrane protein
FDE89_RS06645	COG1169	isochorismate synthase
FDE89_RS06655	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FDE89_RS06660	COG1132	(ABC) transporter
FDE89_RS06665	COG1132	(ABC) transporter
FDE89_RS06680	COG1535	isochorismatase
FDE89_RS06680	COG3433	isochorismatase activity
FDE89_RS06685	COG1021	2,3-dihydroxybenzoate-AMP ligase
FDE89_RS06690	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDE89_RS06700	COG4774	siderophore transport
FDE89_RS06705	COG4607	ABC-type enterochelin transport system periplasmic component
FDE89_RS06710	COG4604	ABC transporter, ATP-binding protein
FDE89_RS06715	COG4605	iron ion homeostasis
FDE89_RS06720	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDE89_RS06725	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDE89_RS06740	COG2964	Protein conserved in bacteria
FDE89_RS06750	COG1741	Belongs to the pirin family
FDE89_RS06770	COG1309	transcriptional regulator
FDE89_RS06780	COG4948	Mandelate Racemase Muconate Lactonizing
FDE89_RS06785	COG2814	Major facilitator Superfamily
FDE89_RS06830	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
FDE89_RS06830	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDE89_RS06835	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDE89_RS06840	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS06850	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDE89_RS06855	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDE89_RS06860	COG0583	DNA-binding transcription factor activity
FDE89_RS06865	COG1113	amino acid transport
FDE89_RS06885	COG2508	Transcriptional regulator
FDE89_RS06885	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
FDE89_RS06920	COG2879	small protein
FDE89_RS06925	COG1966	Carbon starvation protein
FDE89_RS06970	COG1067	ATP-dependent peptidase activity
FDE89_RS06975	COG0583	DNA-binding transcription factor activity
FDE89_RS07000	COG1686	Belongs to the peptidase S11 family
FDE89_RS07005	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDE89_RS07045	COG0616	signal peptide processing
FDE89_RS07050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDE89_RS07060	COG0573	inorganic phosphate transmembrane transporter activity
FDE89_RS07065	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FDE89_RS07070	COG1113	amino acid transport
FDE89_RS07075	COG3961	Belongs to the TPP enzyme family
FDE89_RS07080	COG1522	sequence-specific DNA binding
FDE89_RS07090	COG0076	glutamate decarboxylase activity
FDE89_RS07095	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDE89_RS07105	COG1309	transcriptional regulator
FDE89_RS07120	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDE89_RS07155	COG0352	thiamine-phosphate diphosphorylase activity
FDE89_RS07180	COG0612	Peptidase, M16
FDE89_RS07190	COG1823	symporter activity
FDE89_RS07195	COG0583	DNA-binding transcription factor activity
FDE89_RS07200	COG0477	Major facilitator Superfamily
FDE89_RS07220	COG1187	pseudouridine synthase activity
FDE89_RS07235	COG1686	Belongs to the peptidase S11 family
FDE89_RS07240	COG1252	NADH dehydrogenase
FDE89_RS07250	COG0415	Belongs to the DNA photolyase family
FDE89_RS07265	COG1215	transferase activity, transferring glycosyl groups
FDE89_RS07295	COG2070	2-Nitropropane dioxygenase
FDE89_RS07350	COG0556	nucleotide-excision repair
FDE89_RS07370	COG0436	Aminotransferase
FDE89_RS07400	COG4221	oxidoreductase activity
FDE89_RS07410	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FDE89_RS07415	COG1381	Involved in DNA repair and RecF pathway recombination
FDE89_RS07425	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDE89_RS07440	COG0681	Belongs to the peptidase S26 family
FDE89_RS07455	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDE89_RS07475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FDE89_RS07480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDE89_RS07485	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FDE89_RS07495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FDE89_RS07500	COG4208	sulfate ABC transporter
FDE89_RS07505	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FDE89_RS07510	COG0583	DNA-binding transcription factor activity
FDE89_RS07515	COG4625	pathogenesis
FDE89_RS07530	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FDE89_RS07545	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDE89_RS07555	COG1051	belongs to the nudix hydrolase family
FDE89_RS07555	COG1056	cytidyltransferase-related domain
FDE89_RS07560	COG1024	Enoyl-CoA hydratase
FDE89_RS07570	COG2814	Major facilitator Superfamily
FDE89_RS07575	COG0047	phosphoribosylformylglycinamidine synthase activity
FDE89_RS07575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FDE89_RS07595	COG1473	amidohydrolase
FDE89_RS07600	COG0824	Thioesterase
FDE89_RS07620	COG0823	Involved in the tonB-independent uptake of proteins
FDE89_RS07640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDE89_RS07675	COG0628	permease
FDE89_RS07685	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDE89_RS07690	COG0596	Alpha beta hydrolase
FDE89_RS07695	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDE89_RS07695	COG0616	signal peptide processing
FDE89_RS07705	COG2333	competence protein COMEC
FDE89_RS07705	COG0658	competence protein
FDE89_RS07710	COG1136	(ABC) transporter
FDE89_RS07715	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDE89_RS07745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDE89_RS07765	COG0463	Glycosyl transferase, family 2
FDE89_RS07795	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDE89_RS07800	COG1280	lysine exporter protein (LysE YggA)
FDE89_RS07810	COG0019	diaminopimelate decarboxylase activity
FDE89_RS07820	COG1113	amino acid transport
FDE89_RS07835	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FDE89_RS07845	COG3339	Conserved Protein
FDE89_RS07850	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDE89_RS07855	COG0243	molybdopterin cofactor binding
FDE89_RS07860	COG1929	Belongs to the glycerate kinase type-1 family
FDE89_RS07875	COG0778	Nitroreductase
FDE89_RS07900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDE89_RS07915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDE89_RS07940	COG0741	lytic transglycosylase activity
FDE89_RS07960	COG0584	glycerophosphoryl diester phosphodiesterase
FDE89_RS07990	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDE89_RS07995	COG1597	lipid kinase activity
FDE89_RS08010	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FDE89_RS08015	COG0477	Major facilitator Superfamily
FDE89_RS08065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDE89_RS08070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDE89_RS08095	COG0505	Belongs to the CarA family
FDE89_RS08115	COG0589	response to stress
FDE89_RS08130	COG2843	Capsule synthesis protein
FDE89_RS08185	COG2321	neutral zinc metallopeptidase
FDE89_RS08190	COG2354	Protein conserved in bacteria
FDE89_RS08210	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDE89_RS08235	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDE89_RS08245	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FDE89_RS08250	COG2009	succinate dehydrogenase
FDE89_RS08290	COG2921	Belongs to the UPF0250 family
FDE89_RS08295	COG0321	lipoyl(octanoyl) transferase activity
FDE89_RS08310	COG0531	amino acid
FDE89_RS08325	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FDE89_RS08330	COG1648	precorrin-2 dehydrogenase activity
FDE89_RS08330	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDE89_RS08345	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FDE89_RS08375	COG0671	phosphoesterase, PA-phosphatase related
FDE89_RS08380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDE89_RS08390	COG1538	Outer membrane efflux protein
FDE89_RS08395	COG0393	Putative heavy-metal-binding
FDE89_RS08400	COG0393	Putative heavy-metal-binding
FDE89_RS08410	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS08420	COG0525	valine-tRNA ligase activity
FDE89_RS08440	COG0583	DNA-binding transcription factor activity
FDE89_RS08450	COG0004	ammonium transporteR
FDE89_RS08460	COG0642	Histidine kinase
FDE89_RS08465	COG0745	RESPONSE REGULATOR receiver
FDE89_RS08490	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDE89_RS08505	COG2315	Protein conserved in bacteria
FDE89_RS08510	COG0142	geranyltranstransferase activity
FDE89_RS08515	COG2828	Protein conserved in bacteria
FDE89_RS08520	COG1113	amino acid transport
FDE89_RS08540	COG2207	Transcriptional regulator
FDE89_RS08565	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDE89_RS08575	COG0560	Phosphoserine phosphatase
FDE89_RS08585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDE89_RS08595	COG1530	ribonuclease E activity
FDE89_RS08600	COG0424	maF-like protein
FDE89_RS08605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FDE89_RS08610	COG1792	Involved in formation and maintenance of cell shape
FDE89_RS08615	COG1077	Cell shape determining protein MreB Mrl
FDE89_RS08620	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDE89_RS08630	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDE89_RS08670	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FDE89_RS08675	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDE89_RS08680	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDE89_RS08685	COG1115	amino acid carrier protein
FDE89_RS08705	COG2814	Major facilitator Superfamily
FDE89_RS08710	COG1289	transmembrane transporter activity
FDE89_RS08720	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FDE89_RS08760	COG1376	ErfK ybiS ycfS ynhG family protein
FDE89_RS08765	COG2832	Protein of unknown function (DUF454)
FDE89_RS08775	COG5510	response to toxic substance
FDE89_RS08795	COG0840	transmembrane signaling receptor activity
FDE89_RS08835	COG3422	double-strand break repair
FDE89_RS08840	COG2824	Alkylphosphonate utilization operon protein PhnA
FDE89_RS08845	COG3189	MarR family transcriptional regulator
FDE89_RS08855	COG0354	folic acid binding
FDE89_RS08860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDE89_RS08870	COG0679	Auxin Efflux Carrier
FDE89_RS08875	COG1902	pentaerythritol trinitrate reductase activity
FDE89_RS08890	COG4772	TonB-dependent receptor
FDE89_RS08895	COG2094	Belongs to the DNA glycosylase MPG family
FDE89_RS08920	COG1217	gtp-binding protein TYPA
FDE89_RS08925	COG2233	PERMEase
FDE89_RS08935	COG0833	amino acid
FDE89_RS08940	COG1690	Belongs to the RtcB family
FDE89_RS08945	COG2885	chlorophyll binding
FDE89_RS08945	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FDE89_RS08955	COG0183	Belongs to the thiolase family
FDE89_RS08975	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDE89_RS08995	COG2207	Transcriptional regulator
FDE89_RS09000	COG0183	Belongs to the thiolase family
FDE89_RS09030	COG1272	protein, Hemolysin III
FDE89_RS09035	COG0477	Major facilitator Superfamily
FDE89_RS09050	COG0450	alkyl hydroperoxide reductase
FDE89_RS09070	COG0285	dihydrofolate synthase activity
FDE89_RS09120	COG2096	Adenosyltransferase
FDE89_RS09140	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FDE89_RS09145	COG0745	RESPONSE REGULATOR receiver
FDE89_RS09150	COG2205	protein histidine kinase activity
FDE89_RS09160	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS09165	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS09170	COG0583	DNA-binding transcription factor activity
FDE89_RS09175	COG0625	glutathione transferase activity
FDE89_RS09240	COG0438	transferase activity, transferring glycosyl groups
FDE89_RS09245	COG0463	Glycosyl transferase, family 2
FDE89_RS09250	COG0726	polysaccharide deacetylase
FDE89_RS09270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FDE89_RS09275	COG2205	protein histidine kinase activity
FDE89_RS09305	COG1862	Preprotein translocase
FDE89_RS09315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDE89_RS09320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FDE89_RS09330	COG3781	membrane
FDE89_RS09335	COG0613	PHP domain protein
FDE89_RS09345	COG2350	Protein conserved in bacteria
FDE89_RS09375	COG1607	acyl-coa hydrolase
FDE89_RS09435	COG2199	diguanylate cyclase activity
FDE89_RS09445	COG1408	metallophosphoesterase
FDE89_RS09450	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDE89_RS09460	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FDE89_RS09480	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDE89_RS09485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDE89_RS09500	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FDE89_RS09510	COG2969	positive regulation of protein catabolic process
FDE89_RS09530	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS09535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDE89_RS09550	COG1309	transcriptional regulator
FDE89_RS09555	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS09595	COG1183	phosphatidylcholine synthase activity
FDE89_RS09600	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FDE89_RS09630	COG0741	lytic transglycosylase activity
FDE89_RS09630	COG1196	nuclear chromosome segregation
FDE89_RS09630	COG0739	heme binding
FDE89_RS09680	COG0697	spore germination
FDE89_RS09685	COG2169	Transcriptional regulator
FDE89_RS09690	COG0179	Fumarylacetoacetate (FAA) hydrolase
FDE89_RS09735	COG0557	exoribonuclease II activity
FDE89_RS09740	COG0339	signal peptide processing
FDE89_RS09745	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FDE89_RS09775	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FDE89_RS09780	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS09935	COG0626	cystathionine gamma-synthase activity
FDE89_RS09940	COG0433	COG0433 Predicted ATPase
FDE89_RS09945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDE89_RS09945	COG1017	nitric oxide dioxygenase activity
FDE89_RS09950	COG1959	2 iron, 2 sulfur cluster binding
FDE89_RS09965	COG1301	dicarboxylic acid transport
FDE89_RS09970	COG1946	Acyl-CoA thioesterase
FDE89_RS09990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FDE89_RS10010	COG0494	nUDIX hydrolase
FDE89_RS10020	COG0598	Magnesium transport protein CorA
FDE89_RS10030	COG2854	intermembrane phospholipid transfer
FDE89_RS10040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDE89_RS10045	COG1127	ABC transporter
FDE89_RS10055	COG0513	Belongs to the DEAD box helicase family
FDE89_RS10075	COG0408	coproporphyrinogen oxidase activity
FDE89_RS10090	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS10100	COG1983	PspC domain protein
FDE89_RS10105	COG0517	IMP dehydrogenase activity
FDE89_RS10150	COG0583	DNA-binding transcription factor activity
FDE89_RS10190	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS10200	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDE89_RS10205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDE89_RS10210	COG0833	amino acid
FDE89_RS10240	COG1192	Involved in chromosome partitioning
FDE89_RS10245	COG0628	permease
FDE89_RS10255	COG1289	transmembrane transporter activity
FDE89_RS10270	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDE89_RS10275	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FDE89_RS10285	COG0277	FAD linked oxidase domain protein
FDE89_RS10290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDE89_RS10315	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDE89_RS10320	COG5380	lipid catabolic process
FDE89_RS10340	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDE89_RS10390	COG0194	GDP metabolic process
FDE89_RS10405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDE89_RS10425	COG3307	-O-antigen
FDE89_RS10455	COG1061	Type III restriction enzyme res subunit
FDE89_RS10475	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FDE89_RS10480	COG1704	LemA family
FDE89_RS10490	COG0493	'glutamate synthase
FDE89_RS10495	COG0069	glutamate synthase activity
FDE89_RS10495	COG0067	glutamate synthase
FDE89_RS10495	COG0070	glutamate synthase
FDE89_RS10545	COG2226	methyltransferase
FDE89_RS10560	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDE89_RS10565	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FDE89_RS10610	COG0833	amino acid
FDE89_RS10695	COG0488	(ABC) transporter
FDE89_RS10700	COG2873	o-acetylhomoserine
FDE89_RS10705	COG4221	oxidoreductase activity
FDE89_RS10710	COG0659	secondary active sulfate transmembrane transporter activity
FDE89_RS10735	COG0427	acetyl-CoA hydrolase
FDE89_RS10765	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FDE89_RS10795	COG2329	Antibiotic biosynthesis monooxygenase
FDE89_RS10810	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FDE89_RS10875	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDE89_RS10885	COG1733	regulation of RNA biosynthetic process
FDE89_RS10925	COG0667	Aldo Keto reductase
FDE89_RS10945	COG0583	DNA-binding transcription factor activity
FDE89_RS10950	COG2814	Major facilitator Superfamily
FDE89_RS10980	COG1335	isochorismatase
FDE89_RS10990	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS10995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDE89_RS11005	COG1113	amino acid transport
FDE89_RS11015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDE89_RS11030	COG2814	Major facilitator Superfamily
FDE89_RS11040	COG0351	phosphomethylpyrimidine kinase
FDE89_RS11040	COG0352	thiamine-phosphate diphosphorylase activity
FDE89_RS11040	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDE89_RS11060	COG1309	transcriptional regulator
FDE89_RS11065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FDE89_RS11085	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDE89_RS11095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDE89_RS11100	COG3162	membrane
FDE89_RS11105	COG2205	protein histidine kinase activity
FDE89_RS11105	COG2198	Histidine kinase
FDE89_RS11105	COG0784	Response regulator, receiver
FDE89_RS11130	COG3328	transposase activity
FDE89_RS11135	COG1522	sequence-specific DNA binding
FDE89_RS11140	COG1335	isochorismatase
FDE89_RS11145	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDE89_RS11155	COG0668	transmembrane transport
FDE89_RS11160	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDE89_RS11170	COG1902	pentaerythritol trinitrate reductase activity
FDE89_RS11190	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDE89_RS11215	COG0426	domain, Protein
FDE89_RS11215	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDE89_RS11220	COG4774	siderophore transport
FDE89_RS11225	COG2119	membrane
FDE89_RS11235	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDE89_RS11245	COG4942	peptidase
FDE89_RS11260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FDE89_RS11270	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FDE89_RS11290	COG0189	ligase activity
FDE89_RS11310	COG0708	Exodeoxyribonuclease III
FDE89_RS11315	COG1393	Belongs to the ArsC family
FDE89_RS11330	COG3706	GGDEF domain
FDE89_RS11365	COG2351	hydroxyisourate hydrolase activity
FDE89_RS11370	COG2233	PERMEase
FDE89_RS11380	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDE89_RS11390	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FDE89_RS11395	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS11405	COG3150	esterase
FDE89_RS11420	COG1388	LysM domain
FDE89_RS11420	COG0791	NLP P60 protein
FDE89_RS11435	COG2918	glutathione biosynthetic process
FDE89_RS11450	COG2733	membrane
FDE89_RS11455	COG0436	Aminotransferase
FDE89_RS11460	COG0534	Mate efflux family protein
FDE89_RS11565	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FDE89_RS11570	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDE89_RS11580	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FDE89_RS11585	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDE89_RS11600	COG0010	Belongs to the arginase family
FDE89_RS11630	COG2188	Transcriptional regulator
FDE89_RS11640	COG0523	cobalamin synthesis protein
FDE89_RS11650	COG1113	amino acid transport
FDE89_RS11660	COG0625	glutathione transferase activity
FDE89_RS11680	COG1683	Conserved Protein
FDE89_RS11685	COG0534	Mate efflux family protein
FDE89_RS11690	COG0385	Bile acid
FDE89_RS11695	COG1335	isochorismatase
FDE89_RS11700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDE89_RS11720	COG2116	formate transmembrane transporter activity
FDE89_RS11725	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDE89_RS11730	COG2133	pyrroloquinoline quinone binding
FDE89_RS11735	COG2983	Belongs to the UPF0260 family
FDE89_RS11755	COG1194	a g-specific adenine glycosylase
FDE89_RS11770	COG2818	Glycosylase
FDE89_RS11775	COG1064	alcohol dehydrogenase
FDE89_RS11795	COG0583	DNA-binding transcription factor activity
FDE89_RS11800	COG0656	L-ascorbic acid biosynthetic process
FDE89_RS11805	COG2814	Major facilitator Superfamily
FDE89_RS11840	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDE89_RS11855	COG2233	PERMEase
FDE89_RS11895	COG0733	neurotransmitter:sodium symporter activity
FDE89_RS11935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDE89_RS11940	COG0657	acetylesterase activity
FDE89_RS11990	COG2951	lytic endotransglycosylase activity
FDE89_RS11995	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FDE89_RS12015	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
FDE89_RS12025	COG0671	phosphoesterase, PA-phosphatase related
FDE89_RS12030	COG0861	Integral membrane protein TerC family
FDE89_RS12040	COG0754	glutathionylspermidine amidase activity
FDE89_RS12050	COG0402	S-adenosylhomocysteine deaminase activity
FDE89_RS12065	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDE89_RS12070	COG1230	cation diffusion facilitator family transporter
FDE89_RS12085	COG0706	membrane insertase activity
FDE89_RS12110	COG0592	DNA-directed DNA polymerase activity
FDE89_RS12120	COG0187	DNA topoisomerase II activity
FDE89_RS12130	COG0586	Pfam SNARE associated Golgi protein
FDE89_RS12135	COG0488	(ABC) transporter
FDE89_RS12160	COG0596	Alpha beta hydrolase
FDE89_RS12165	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FDE89_RS12170	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDE89_RS12205	COG1047	Peptidyl-prolyl cis-trans
FDE89_RS12215	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDE89_RS12220	COG0196	riboflavin kinase activity
FDE89_RS12230	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDE89_RS12235	COG1309	transcriptional regulator
FDE89_RS12240	COG1116	anion transmembrane transporter activity
FDE89_RS12245	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDE89_RS12250	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDE89_RS12255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDE89_RS12260	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDE89_RS12280	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS12285	COG0546	phosphoglycolate phosphatase activity
FDE89_RS12340	COG3023	N-Acetylmuramoyl-L-alanine amidase
FDE89_RS12345	COG0728	peptidoglycan biosynthetic process
FDE89_RS12375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FDE89_RS12385	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FDE89_RS12390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FDE89_RS12395	COG2089	acid synthase
FDE89_RS12405	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDE89_RS12410	COG1083	cytidylyl-transferase
FDE89_RS12415	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS12425	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS12465	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
FDE89_RS12480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FDE89_RS12495	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FDE89_RS12510	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDE89_RS12515	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDE89_RS12525	COG2186	Transcriptional regulator
FDE89_RS12535	COG0277	FAD linked oxidase domain protein
FDE89_RS12540	COG1448	Aminotransferase
FDE89_RS12550	COG1802	Transcriptional regulator
FDE89_RS12565	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FDE89_RS12600	COG2801	Transposase and inactivated derivatives
FDE89_RS12655	COG0564	pseudouridine synthase activity
FDE89_RS12695	COG0251	oxidation-reduction process
FDE89_RS12700	COG1113	amino acid transport
FDE89_RS12705	COG1113	amino acid transport
FDE89_RS12725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDE89_RS12730	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS12735	COG1024	Enoyl-CoA hydratase
FDE89_RS12740	COG1024	Enoyl-CoA hydratase
FDE89_RS12750	COG3916	Acyl-homoserine-lactone synthase
FDE89_RS12760	COG2197	response regulator
FDE89_RS12770	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS12775	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDE89_RS12775	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
FDE89_RS12775	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
FDE89_RS12775	COG3321	synthase
FDE89_RS12785	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDE89_RS12800	COG2267	carboxylic ester hydrolase activity
FDE89_RS12870	COG0673	inositol 2-dehydrogenase activity
FDE89_RS12875	COG1324	tolerance protein
FDE89_RS12905	COG2826	transposase and inactivated derivatives, IS30 family
FDE89_RS12940	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDE89_RS12970	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FDE89_RS12975	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDE89_RS13000	COG1570	exodeoxyribonuclease VII activity
FDE89_RS13015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDE89_RS13020	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDE89_RS13025	COG2194	sulfuric ester hydrolase activity
FDE89_RS13030	COG0745	RESPONSE REGULATOR receiver
FDE89_RS13035	COG0642	Histidine kinase
FDE89_RS13130	COG3756	Protein conserved in bacteria
FDE89_RS13165	COG0271	Belongs to the BolA IbaG family
FDE89_RS13175	COG1192	Involved in chromosome partitioning
FDE89_RS13190	COG0586	Pfam SNARE associated Golgi protein
FDE89_RS13195	COG2259	Doxx family
FDE89_RS13200	COG4399	Belongs to the UPF0754 family
FDE89_RS13205	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDE89_RS13205	COG0519	Catalyzes the synthesis of GMP from XMP
FDE89_RS13250	COG0281	malic enzyme
FDE89_RS13260	COG2837	iron assimilation
FDE89_RS13265	COG1280	lysine exporter protein (LysE YggA)
FDE89_RS13270	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDE89_RS13275	COG1121	(ABC) transporter
FDE89_RS13340	COG0386	Belongs to the glutathione peroxidase family
FDE89_RS13355	COG1309	transcriptional regulator
FDE89_RS13360	COG0697	spore germination
FDE89_RS13405	COG1309	transcriptional regulator
FDE89_RS13430	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FDE89_RS13440	COG0655	NAD(P)H dehydrogenase (quinone) activity
FDE89_RS13495	COG1253	flavin adenine dinucleotide binding
FDE89_RS13505	COG2860	membrane
FDE89_RS13510	COG0477	Major facilitator Superfamily
FDE89_RS13520	COG0318	PFAM AMP-dependent synthetase and ligase
FDE89_RS13535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDE89_RS13550	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDE89_RS13565	COG0606	chelatase, subunit chli
FDE89_RS13595	COG0589	response to stress
FDE89_RS13600	COG0659	secondary active sulfate transmembrane transporter activity
FDE89_RS13685	COG0606	chelatase, subunit chli
FDE89_RS13695	COG0347	Belongs to the P(II) protein family
FDE89_RS13700	COG0004	ammonium transporteR
FDE89_RS13710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDE89_RS13710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDE89_RS13750	COG0795	lipopolysaccharide-transporting ATPase activity
FDE89_RS13755	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FDE89_RS13760	COG0793	Belongs to the peptidase S41A family
FDE89_RS13775	COG2197	response regulator
FDE89_RS13785	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FDE89_RS13795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDE89_RS13800	COG4974	Belongs to the 'phage' integrase family
FDE89_RS13825	COG0772	Belongs to the SEDS family
FDE89_RS13830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDE89_RS13835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDE89_RS13840	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDE89_RS13865	COG0697	spore germination
FDE89_RS13870	COG1538	Outer membrane efflux protein
FDE89_RS13890	COG3275	phosphorelay sensor kinase activity
FDE89_RS13900	COG0181	hydroxymethylbilane synthase activity
FDE89_RS13950	COG1716	ATPase activity
FDE89_RS13955	COG0546	phosphoglycolate phosphatase activity
FDE89_RS14050	COG0596	Alpha beta hydrolase
FDE89_RS14055	COG2056	Na+-H+ antiporter family
FDE89_RS14070	COG0326	Molecular chaperone. Has ATPase activity
FDE89_RS14085	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FDE89_RS14155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FDE89_RS14160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDE89_RS14160	COG2169	Transcriptional regulator
FDE89_RS14190	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDE89_RS14200	COG0497	DNA recombination
FDE89_RS14215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDE89_RS14225	COG0237	dephospho-CoA kinase activity
FDE89_RS14275	COG0195	Participates in both transcription termination and antitermination
FDE89_RS14290	COG1320	monovalent cation:proton antiporter activity
FDE89_RS14295	COG2212	antiporter activity
FDE89_RS14300	COG1863	multisubunit Na H antiporter MnhE subunit
FDE89_RS14305	COG0651	ATP synthesis coupled electron transport
FDE89_RS14310	COG1006	Multisubunit Na H antiporter MnhC subunit
FDE89_RS14315	COG2111	Na H antiporter
FDE89_RS14315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDE89_RS14330	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDE89_RS14335	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDE89_RS14350	COG2226	methyltransferase
FDE89_RS14370	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FDE89_RS14375	COG1074	ATP-dependent DNA helicase activity
FDE89_RS14380	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDE89_RS14385	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FDE89_RS14400	COG0598	Magnesium transport protein CorA
FDE89_RS14405	COG0789	Transcriptional regulator
FDE89_RS14410	COG0484	heat shock protein binding
FDE89_RS14420	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
FDE89_RS14425	COG0475	glutathione-regulated potassium exporter activity
FDE89_RS14425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDE89_RS14430	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FDE89_RS14450	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDE89_RS14460	COG4535	Mg2 and Co2 transporter CorC
FDE89_RS14465	COG0425	Belongs to the sulfur carrier protein TusA family
FDE89_RS14470	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FDE89_RS14470	COG0644	oxidoreductase
FDE89_RS14480	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDE89_RS14495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDE89_RS14500	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FDE89_RS14540	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDE89_RS14555	COG0534	Mate efflux family protein
FDE89_RS14565	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FDE89_RS14570	COG4221	oxidoreductase activity
FDE89_RS14575	COG0583	DNA-binding transcription factor activity
FDE89_RS14590	COG0318	PFAM AMP-dependent synthetase and ligase
FDE89_RS14595	COG1530	ribonuclease E activity
FDE89_RS14610	COG0546	phosphoglycolate phosphatase activity
FDE89_RS14615	COG2378	regulation of single-species biofilm formation
FDE89_RS14620	COG0625	glutathione transferase activity
FDE89_RS14630	COG0583	DNA-binding transcription factor activity
FDE89_RS14695	COG0473	3-isopropylmalate dehydrogenase activity
FDE89_RS14750	COG1301	dicarboxylic acid transport
FDE89_RS14760	COG1560	Kdo2-lipid A biosynthetic process
FDE89_RS14765	COG1280	lysine exporter protein (LysE YggA)
FDE89_RS14770	COG0488	(ABC) transporter
FDE89_RS14775	COG2900	Belongs to the SlyX family
FDE89_RS14785	COG1733	regulation of RNA biosynthetic process
FDE89_RS14810	COG0210	DNA helicase
FDE89_RS14815	COG0724	RNA recognition motif
FDE89_RS14835	COG4651	solute:proton antiporter activity
FDE89_RS14835	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDE89_RS14860	COG0788	formyltetrahydrofolate deformylase activity
FDE89_RS14960	COG2813	Specifically methylates the guanine in position
FDE89_RS14960	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDE89_RS14970	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDE89_RS14990	COG0740	serine-type endopeptidase activity
FDE89_RS15010	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FDE89_RS15010	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FDE89_RS15015	COG0857	belongs to the CobB CobQ family
FDE89_RS15015	COG0280	phosphate acetyltransferase
FDE89_RS15020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDE89_RS15030	COG0800	Aldolase
FDE89_RS15040	COG3265	gluconokinase activity
FDE89_RS15045	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS15055	COG2267	carboxylic ester hydrolase activity
FDE89_RS15070	COG0793	Belongs to the peptidase S41A family
FDE89_RS15105	COG1426	Protein conserved in bacteria
FDE89_RS15150	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
FDE89_RS15160	COG0318	PFAM AMP-dependent synthetase and ligase
FDE89_RS15175	COG2986	histidine ammonia-lyase
FDE89_RS15215	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS15220	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
FDE89_RS15240	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDE89_RS15250	COG1162	GTPase activity
FDE89_RS15255	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FDE89_RS15270	COG1538	Outer membrane efflux protein
FDE89_RS15275	COG1136	(ABC) transporter
FDE89_RS15275	COG0577	efflux transmembrane transporter activity
FDE89_RS15280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDE89_RS15305	COG0028	Belongs to the TPP enzyme family
FDE89_RS15310	COG0440	acetolactate synthase activity
FDE89_RS15350	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDE89_RS15365	COG0084	hydrolase, TatD family'
FDE89_RS15380	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FDE89_RS15390	COG0583	DNA-binding transcription factor activity
FDE89_RS15400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDE89_RS15405	COG2814	Major facilitator Superfamily
FDE89_RS15415	COG0697	spore germination
FDE89_RS15445	COG3622	Belongs to the hyi family
FDE89_RS15450	COG2084	Dehydrogenase
FDE89_RS15455	COG1024	Enoyl-CoA hydratase
FDE89_RS15460	COG5002	protein histidine kinase activity
FDE89_RS15460	COG2205	protein histidine kinase activity
FDE89_RS15460	COG0784	Response regulator, receiver
FDE89_RS15480	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDE89_RS15490	COG3956	TIGRFAM MazG family protein
FDE89_RS15495	COG1555	photosystem II stabilization
FDE89_RS15500	COG0617	tRNA 3'-terminal CCA addition
FDE89_RS15505	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDE89_RS15525	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDE89_RS15530	COG3028	Belongs to the UPF0307 family
FDE89_RS15535	COG0318	PFAM AMP-dependent synthetase and ligase
FDE89_RS15555	COG0625	glutathione transferase activity
FDE89_RS15560	COG1238	metal cluster binding
FDE89_RS15600	COG0072	phenylalanine-tRNA ligase activity
FDE89_RS15630	COG0248	Ppx GppA phosphatase
FDE89_RS15640	COG0037	tRNA processing
FDE89_RS15690	COG1764	response to oxidative stress
FDE89_RS15695	COG1846	Transcriptional regulator
FDE89_RS15705	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDE89_RS15750	COG1765	OsmC-like protein
FDE89_RS15760	COG0667	Aldo Keto reductase
FDE89_RS15775	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDE89_RS15785	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDE89_RS15795	COG0527	aspartate kinase activity
FDE89_RS15805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FDE89_RS15815	COG3038	cytochrome b561
FDE89_RS15820	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDE89_RS15825	COG2252	PERMEase
FDE89_RS15835	COG2072	flavoprotein involved in K transport
FDE89_RS15850	COG1741	Belongs to the pirin family
FDE89_RS15855	COG1309	transcriptional regulator
FDE89_RS15900	COG1902	pentaerythritol trinitrate reductase activity
FDE89_RS15900	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDE89_RS15910	COG2203	Gaf domain
FDE89_RS15910	COG3706	GGDEF domain
FDE89_RS15910	COG5001	Diguanylate cyclase
FDE89_RS15910	COG4251	negative regulation of phosphorylation
FDE89_RS15940	COG4172	Belongs to the ABC transporter superfamily
FDE89_RS15945	COG4239	(ABC) transporter, permease
FDE89_RS15950	COG4174	ABC transporter (Permease)
FDE89_RS15960	COG1388	LysM domain
FDE89_RS15960	COG1388	LysM domain
FDE89_RS15960	COG0741	lytic transglycosylase activity
FDE89_RS15960	COG0741	lytic transglycosylase activity
FDE89_RS15965	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDE89_RS16005	COG0583	DNA-binding transcription factor activity
FDE89_RS16010	COG1279	arginine transmembrane transporter activity
FDE89_RS16030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDE89_RS16035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDE89_RS16040	COG0006	proline dipeptidase activity
FDE89_RS16130	COG0739	heme binding
FDE89_RS16455	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDE89_RS16480	COG3384	dioxygenase
FDE89_RS16490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDE89_RS16495	COG2878	Part of a membrane complex involved in electron transport
FDE89_RS16500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDE89_RS16525	COG0768	penicillin binding
FDE89_RS16530	COG0742	ribosomal rna small subunit methyltransferase
FDE89_RS16545	COG0830	nickel cation binding
FDE89_RS16555	COG0804	urea catabolic process
FDE89_RS16595	COG1253	flavin adenine dinucleotide binding
FDE89_RS16605	COG2851	Citrate transporter
FDE89_RS16665	COG1773	rubredoxin
FDE89_RS16670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDE89_RS16680	COG0583	DNA-binding transcription factor activity
FDE89_RS16705	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FDE89_RS16710	COG4181	ATPase activity
FDE89_RS16755	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDE89_RS16775	COG0306	phosphate transporter
FDE89_RS16785	COG3958	Transketolase
FDE89_RS16790	COG3959	Transketolase, thiamine diphosphate binding domain
FDE89_RS16795	COG2271	Major facilitator Superfamily
FDE89_RS16800	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS16805	COG0583	DNA-binding transcription factor activity
FDE89_RS16825	COG2223	nitrite transmembrane transporter activity
FDE89_RS16830	COG2207	Transcriptional regulator
FDE89_RS16835	COG2066	Belongs to the glutaminase family
FDE89_RS16840	COG0242	peptide deformylase activity
FDE89_RS16845	COG0477	Major facilitator Superfamily
FDE89_RS16855	COG0028	Belongs to the TPP enzyme family
FDE89_RS16870	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS16875	COG2267	carboxylic ester hydrolase activity
FDE89_RS16885	COG2271	Major facilitator Superfamily
FDE89_RS16890	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDE89_RS16900	COG1028	Short-chain dehydrogenase reductase Sdr
FDE89_RS16920	COG1414	Transcriptional regulator
FDE89_RS16935	COG1024	Enoyl-CoA hydratase
FDE89_RS16945	COG1215	transferase activity, transferring glycosyl groups
FDE89_RS16950	COG1649	PFAM Uncharacterised BCR, COG1649
FDE89_RS16950	COG0726	polysaccharide deacetylase
FDE89_RS16960	COG4681	YaeQ
FDE89_RS16970	COG0523	cobalamin synthesis protein
FDE89_RS16980	COG1607	acyl-coa hydrolase
FDE89_RS16990	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDE89_RS16995	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDE89_RS17000	COG1309	transcriptional regulator
FDE89_RS17025	COG2040	homocysteine
FDE89_RS17030	COG0531	amino acid
FDE89_RS17085	COG1595	DNA-templated transcription, initiation
FDE89_RS17095	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDE89_RS17100	COG0477	Major facilitator Superfamily
FDE89_RS17120	COG0084	hydrolase, TatD family'
FDE89_RS17345	COG2026	Addiction module toxin, RelE StbE family
FDE89_RS17540	COG1484	DNA-dependent DNA replication
FDE89_RS17630	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDE89_RS17695	COG0405	Gamma-glutamyltransferase
FDE89_RS17700	COG2814	Major facilitator Superfamily
FDE89_RS17710	COG2050	protein possibly involved in aromatic compounds catabolism
FDE89_RS17725	COG1090	epimerase
FDE89_RS17745	COG0420	3'-5' exonuclease activity
FDE89_RS17770	COG0735	belongs to the Fur family
FDE89_RS17775	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDE89_RS17800	COG0121	glutamine amidotransferase
FDE89_RS17815	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDE89_RS17825	COG0210	DNA helicase
FDE89_RS17830	COG2885	chlorophyll binding
FDE89_RS17835	COG0204	Acyl-transferase
FDE89_RS17850	COG2894	cell division
FDE89_RS17870	COG1280	lysine exporter protein (LysE YggA)
FDE89_RS17875	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FDE89_RS17875	COG1674	ftsk spoiiie
FDE89_RS17880	COG0492	ferredoxin-NADP+ reductase activity
FDE89_RS17885	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FDE89_RS17895	COG0456	acetyltransferase
FDE89_RS17940	COG1981	membrane
FDE89_RS17955	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDE89_RS17955	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDE89_RS17975	COG1012	belongs to the aldehyde dehydrogenase family
FDE89_RS17985	COG0657	acetylesterase activity
FDE89_RS17995	COG0473	3-isopropylmalate dehydrogenase activity
FDE89_RS18000	COG0583	DNA-binding transcription factor activity
FDE89_RS18020	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDE89_RS18045	COG0564	pseudouridine synthase activity
FDE89_RS18055	COG0358	DNA primase activity
FDE89_RS18070	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FDE89_RS18100	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDE89_RS18130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDE89_RS18140	COG0352	thiamine-phosphate diphosphorylase activity
FDE89_RS18140	COG0351	phosphomethylpyrimidine kinase
FDE89_RS18140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDE89_RS18145	COG1652	LysM domain
FDE89_RS18170	COG1399	metal-binding, possibly nucleic acid-binding protein
FDE89_RS18175	COG3101	peptidyl-lysine hydroxylation
FDE89_RS18180	COG0009	L-threonylcarbamoyladenylate synthase
FDE89_RS18185	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FDE89_RS18190	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FDE89_RS18205	COG4106	trans-aconitate 2-methyltransferase activity
FDE89_RS18220	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDE89_RS18220	COG0596	Alpha beta hydrolase
FDE89_RS18220	COG2226	methyltransferase
FDE89_RS18225	COG1877	trehalose-phosphatase activity
FDE89_RS18230	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FDE89_RS18235	COG2223	nitrite transmembrane transporter activity
FDE89_RS18255	COG1196	nuclear chromosome segregation
FDE89_RS18265	COG0730	response to heat
FDE89_RS18280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDE89_RS18290	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDE89_RS18350	COG0489	protein tyrosine kinase activity
FDE89_RS18360	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDE89_RS18360	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDE89_RS18390	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FDE89_RS18395	COG2081	HI0933 family
FDE89_RS18405	COG0668	transmembrane transport
FDE89_RS18425	COG0583	DNA-binding transcription factor activity
FDE89_RS18445	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FDE89_RS18450	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDE89_RS18480	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FDE89_RS18520	COG0745	RESPONSE REGULATOR receiver
FDE89_RS18540	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDE89_RS18550	COG2205	protein histidine kinase activity
FDE89_RS18620	COG4993	Dehydrogenase
FDE89_RS18640	COG0384	phenazine biosynthesis protein PhzF
FDE89_RS18670	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDE89_RS18685	COG0583	DNA-binding transcription factor activity
FDE89_RS18715	COG0583	DNA-binding transcription factor activity
FDE89_RS18735	COG0583	DNA-binding transcription factor activity
FDE89_RS18740	COG1053	succinate dehydrogenase
FDE89_RS18750	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDE89_RS18755	COG2814	Major facilitator Superfamily
FDE89_RS18760	COG1960	acyl-CoA dehydrogenase activity
FDE89_RS18765	COG0583	DNA-binding transcription factor activity
FDE89_RS18770	COG1063	alcohol dehydrogenase
FDE89_RS18805	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FDE89_RS18810	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FDE89_RS18815	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDE89_RS18830	COG3667	copper resistance
FDE89_RS18835	COG2132	Multicopper oxidase
FDE89_RS18845	COG0561	phosphatase activity
FDE89_RS18850	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FDE89_RS18875	COG1214	PFAM Peptidase M22, glycoprotease
FDE89_RS18930	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
FDE89_RS18940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FDE89_RS18945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDE89_RS18950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDE89_RS19010	COG1764	response to oxidative stress
FDE89_RS19060	COG2832	Protein of unknown function (DUF454)