locus-tag	class	description
FDF20_RS00010	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDF20_RS00015	COG4974	Belongs to the 'phage' integrase family
FDF20_RS00040	COG0772	Belongs to the SEDS family
FDF20_RS00045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDF20_RS00050	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
FDF20_RS00055	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDF20_RS00080	COG0697	spore germination
FDF20_RS00085	COG1538	Outer membrane efflux protein
FDF20_RS00105	COG3275	phosphorelay sensor kinase activity
FDF20_RS00115	COG0181	hydroxymethylbilane synthase activity
FDF20_RS00170	COG1061	Type III restriction enzyme res subunit
FDF20_RS00190	COG1716	ATPase activity
FDF20_RS00195	COG0546	phosphoglycolate phosphatase activity
FDF20_RS00290	COG0596	Alpha beta hydrolase
FDF20_RS00295	COG2056	Na+-H+ antiporter family
FDF20_RS00310	COG0326	Molecular chaperone. Has ATPase activity
FDF20_RS00325	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
FDF20_RS00385	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FDF20_RS00390	COG2169	Transcriptional regulator
FDF20_RS00390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDF20_RS00420	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
FDF20_RS00430	COG0497	DNA recombination
FDF20_RS00445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDF20_RS00455	COG0237	dephospho-CoA kinase activity
FDF20_RS00505	COG0195	Participates in both transcription termination and antitermination
FDF20_RS00520	COG1320	monovalent cation:proton antiporter activity
FDF20_RS00525	COG2212	antiporter activity
FDF20_RS00530	COG1863	multisubunit Na H antiporter MnhE subunit
FDF20_RS00535	COG0651	ATP synthesis coupled electron transport
FDF20_RS00540	COG1006	Multisubunit Na H antiporter MnhC subunit
FDF20_RS00545	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDF20_RS00545	COG2111	Na H antiporter
FDF20_RS00560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
FDF20_RS00580	COG2226	methyltransferase
FDF20_RS00600	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
FDF20_RS00605	COG1074	ATP-dependent DNA helicase activity
FDF20_RS00610	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDF20_RS00615	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FDF20_RS00630	COG0598	Magnesium transport protein CorA
FDF20_RS00635	COG0789	Transcriptional regulator
FDF20_RS00640	COG0484	heat shock protein binding
FDF20_RS00655	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDF20_RS00655	COG0475	glutathione-regulated potassium exporter activity
FDF20_RS00660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FDF20_RS00680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDF20_RS00690	COG4535	Mg2 and Co2 transporter CorC
FDF20_RS00695	COG0425	Belongs to the sulfur carrier protein TusA family
FDF20_RS00705	COG0644	oxidoreductase
FDF20_RS00705	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
FDF20_RS00715	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDF20_RS00730	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF20_RS00735	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
FDF20_RS00745	COG0493	'glutamate synthase
FDF20_RS00745	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDF20_RS00770	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
FDF20_RS00785	COG0534	Mate efflux family protein
FDF20_RS00795	COG0635	Involved in the biosynthesis of porphyrin-containing compound
FDF20_RS00800	COG4221	oxidoreductase activity
FDF20_RS00805	COG0583	DNA-binding transcription factor activity
FDF20_RS00820	COG0318	PFAM AMP-dependent synthetase and ligase
FDF20_RS00825	COG1530	ribonuclease E activity
FDF20_RS00840	COG0546	phosphoglycolate phosphatase activity
FDF20_RS00845	COG2378	regulation of single-species biofilm formation
FDF20_RS00850	COG0625	glutathione transferase activity
FDF20_RS00860	COG0583	DNA-binding transcription factor activity
FDF20_RS00925	COG0473	3-isopropylmalate dehydrogenase activity
FDF20_RS00990	COG1560	Kdo2-lipid A biosynthetic process
FDF20_RS00995	COG1280	lysine exporter protein (LysE YggA)
FDF20_RS01000	COG0488	(ABC) transporter
FDF20_RS01005	COG2900	Belongs to the SlyX family
FDF20_RS01015	COG1733	regulation of RNA biosynthetic process
FDF20_RS01040	COG0210	DNA helicase
FDF20_RS01045	COG0724	RNA recognition motif
FDF20_RS01060	COG4651	solute:proton antiporter activity
FDF20_RS01060	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FDF20_RS01085	COG0788	formyltetrahydrofolate deformylase activity
FDF20_RS01185	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDF20_RS01185	COG2813	Specifically methylates the guanine in position
FDF20_RS01195	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDF20_RS01205	COG4774	siderophore transport
FDF20_RS01215	COG0740	serine-type endopeptidase activity
FDF20_RS01235	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
FDF20_RS01235	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
FDF20_RS01240	COG0857	belongs to the CobB CobQ family
FDF20_RS01240	COG0280	phosphate acetyltransferase
FDF20_RS01245	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FDF20_RS01255	COG0800	Aldolase
FDF20_RS01265	COG3265	gluconokinase activity
FDF20_RS01270	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS01280	COG2267	carboxylic ester hydrolase activity
FDF20_RS01295	COG0793	Belongs to the peptidase S41A family
FDF20_RS01330	COG1426	Protein conserved in bacteria
FDF20_RS01370	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
FDF20_RS01380	COG1162	GTPase activity
FDF20_RS01385	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
FDF20_RS01400	COG1538	Outer membrane efflux protein
FDF20_RS01405	COG0577	efflux transmembrane transporter activity
FDF20_RS01405	COG1136	(ABC) transporter
FDF20_RS01410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF20_RS01435	COG0028	Belongs to the TPP enzyme family
FDF20_RS01440	COG0440	acetolactate synthase activity
FDF20_RS01475	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
FDF20_RS01490	COG0084	hydrolase, TatD family'
FDF20_RS01500	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
FDF20_RS01510	COG0583	DNA-binding transcription factor activity
FDF20_RS01520	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDF20_RS01590	COG3646	Phage regulatory protein
FDF20_RS01600	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
FDF20_RS01740	COG4695	Portal protein
FDF20_RS01840	COG2205	protein histidine kinase activity
FDF20_RS01855	COG2132	Multicopper oxidase
FDF20_RS01875	COG2814	Major facilitator Superfamily
FDF20_RS01885	COG0697	spore germination
FDF20_RS01920	COG3622	Belongs to the hyi family
FDF20_RS01930	COG1024	Enoyl-CoA hydratase
FDF20_RS01935	COG5002	protein histidine kinase activity
FDF20_RS01935	COG2205	protein histidine kinase activity
FDF20_RS01935	COG0784	Response regulator, receiver
FDF20_RS01955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDF20_RS01965	COG3956	TIGRFAM MazG family protein
FDF20_RS01970	COG1555	photosystem II stabilization
FDF20_RS01975	COG0617	tRNA 3'-terminal CCA addition
FDF20_RS01980	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FDF20_RS02000	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDF20_RS02005	COG3028	Belongs to the UPF0307 family
FDF20_RS02010	COG0318	PFAM AMP-dependent synthetase and ligase
FDF20_RS02030	COG0625	glutathione transferase activity
FDF20_RS02035	COG1238	metal cluster binding
FDF20_RS02075	COG0072	phenylalanine-tRNA ligase activity
FDF20_RS02105	COG0248	Ppx GppA phosphatase
FDF20_RS02115	COG0037	tRNA processing
FDF20_RS02155	COG1764	response to oxidative stress
FDF20_RS02160	COG1846	Transcriptional regulator
FDF20_RS02170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDF20_RS02230	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FDF20_RS02235	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
FDF20_RS02240	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
FDF20_RS02300	COG1214	PFAM Peptidase M22, glycoprotease
FDF20_RS02315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FDF20_RS02325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FDF20_RS02330	COG0561	phosphatase activity
FDF20_RS02340	COG2132	Multicopper oxidase
FDF20_RS02360	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FDF20_RS02365	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
FDF20_RS02370	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FDF20_RS02400	COG1063	alcohol dehydrogenase
FDF20_RS02405	COG0583	DNA-binding transcription factor activity
FDF20_RS02410	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS02415	COG2814	Major facilitator Superfamily
FDF20_RS02420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDF20_RS02430	COG1053	succinate dehydrogenase
FDF20_RS02435	COG0583	DNA-binding transcription factor activity
FDF20_RS02455	COG0583	DNA-binding transcription factor activity
FDF20_RS02490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF20_RS02540	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS02550	COG0477	Major facilitator Superfamily
FDF20_RS02585	COG0697	spore germination
FDF20_RS02590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FDF20_RS02610	COG0745	RESPONSE REGULATOR receiver
FDF20_RS02650	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FDF20_RS02680	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
FDF20_RS02685	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
FDF20_RS02710	COG0583	DNA-binding transcription factor activity
FDF20_RS02730	COG0668	transmembrane transport
FDF20_RS02740	COG2081	HI0933 family
FDF20_RS02745	COG2515	1-aminocyclopropane-1-carboxylate deaminase
FDF20_RS02775	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDF20_RS02775	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
FDF20_RS02785	COG0489	protein tyrosine kinase activity
FDF20_RS02845	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
FDF20_RS02855	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
FDF20_RS02870	COG0730	response to heat
FDF20_RS02880	COG1196	nuclear chromosome segregation
FDF20_RS02900	COG2223	nitrite transmembrane transporter activity
FDF20_RS02905	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
FDF20_RS02910	COG1877	trehalose-phosphatase activity
FDF20_RS02915	COG2226	methyltransferase
FDF20_RS02915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDF20_RS02915	COG0596	Alpha beta hydrolase
FDF20_RS02930	COG4106	trans-aconitate 2-methyltransferase activity
FDF20_RS02945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FDF20_RS02950	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FDF20_RS02955	COG0009	L-threonylcarbamoyladenylate synthase
FDF20_RS02960	COG3101	peptidyl-lysine hydroxylation
FDF20_RS02965	COG1399	metal-binding, possibly nucleic acid-binding protein
FDF20_RS02990	COG1652	LysM domain
FDF20_RS02995	COG0351	phosphomethylpyrimidine kinase
FDF20_RS02995	COG0352	thiamine-phosphate diphosphorylase activity
FDF20_RS02995	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDF20_RS03005	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
FDF20_RS03040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDF20_RS03070	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
FDF20_RS03085	COG0358	DNA primase activity
FDF20_RS03095	COG0564	pseudouridine synthase activity
FDF20_RS03120	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDF20_RS03140	COG0583	DNA-binding transcription factor activity
FDF20_RS03145	COG0473	3-isopropylmalate dehydrogenase activity
FDF20_RS03155	COG0657	acetylesterase activity
FDF20_RS03165	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS03185	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
FDF20_RS03185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FDF20_RS03200	COG1981	membrane
FDF20_RS03245	COG0456	acetyltransferase
FDF20_RS03255	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
FDF20_RS03260	COG0492	ferredoxin-NADP+ reductase activity
FDF20_RS03265	COG1674	ftsk spoiiie
FDF20_RS03265	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
FDF20_RS03270	COG1280	lysine exporter protein (LysE YggA)
FDF20_RS03285	COG2894	cell division
FDF20_RS03300	COG0204	Acyl-transferase
FDF20_RS03305	COG2885	chlorophyll binding
FDF20_RS03310	COG0210	DNA helicase
FDF20_RS03320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDF20_RS03335	COG0121	glutamine amidotransferase
FDF20_RS03360	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FDF20_RS03365	COG0735	belongs to the Fur family
FDF20_RS03390	COG0420	3'-5' exonuclease activity
FDF20_RS03415	COG1090	epimerase
FDF20_RS03430	COG2050	protein possibly involved in aromatic compounds catabolism
FDF20_RS03440	COG2814	Major facilitator Superfamily
FDF20_RS03445	COG0405	Gamma-glutamyltransferase
FDF20_RS03505	COG0477	Major facilitator Superfamily
FDF20_RS03510	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF20_RS03520	COG1595	DNA-templated transcription, initiation
FDF20_RS03575	COG0531	amino acid
FDF20_RS03580	COG2040	homocysteine
FDF20_RS03605	COG1309	transcriptional regulator
FDF20_RS03610	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDF20_RS03615	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDF20_RS03625	COG1607	acyl-coa hydrolase
FDF20_RS03635	COG0523	cobalamin synthesis protein
FDF20_RS03645	COG4681	YaeQ
FDF20_RS03655	COG0726	polysaccharide deacetylase
FDF20_RS03655	COG1649	PFAM Uncharacterised BCR, COG1649
FDF20_RS03660	COG1215	transferase activity, transferring glycosyl groups
FDF20_RS03670	COG1024	Enoyl-CoA hydratase
FDF20_RS03685	COG1414	Transcriptional regulator
FDF20_RS03705	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS03715	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDF20_RS03720	COG2271	Major facilitator Superfamily
FDF20_RS03730	COG2267	carboxylic ester hydrolase activity
FDF20_RS03735	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS03750	COG0028	Belongs to the TPP enzyme family
FDF20_RS03760	COG0477	Major facilitator Superfamily
FDF20_RS03765	COG0242	peptide deformylase activity
FDF20_RS03770	COG2066	Belongs to the glutaminase family
FDF20_RS03775	COG2207	Transcriptional regulator
FDF20_RS03780	COG2223	nitrite transmembrane transporter activity
FDF20_RS03800	COG0583	DNA-binding transcription factor activity
FDF20_RS03805	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS03810	COG2271	Major facilitator Superfamily
FDF20_RS03815	COG3959	Transketolase, thiamine diphosphate binding domain
FDF20_RS03820	COG3958	Transketolase
FDF20_RS03830	COG0306	phosphate transporter
FDF20_RS03850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDF20_RS03895	COG4181	ATPase activity
FDF20_RS03900	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
FDF20_RS03930	COG0583	DNA-binding transcription factor activity
FDF20_RS03940	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF20_RS03945	COG1773	rubredoxin
FDF20_RS03995	COG2851	Citrate transporter
FDF20_RS04005	COG1253	flavin adenine dinucleotide binding
FDF20_RS04045	COG0804	urea catabolic process
FDF20_RS04055	COG0830	nickel cation binding
FDF20_RS04070	COG0742	ribosomal rna small subunit methyltransferase
FDF20_RS04075	COG0768	penicillin binding
FDF20_RS04100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
FDF20_RS04105	COG2878	Part of a membrane complex involved in electron transport
FDF20_RS04110	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDF20_RS04120	COG3384	dioxygenase
FDF20_RS04145	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
FDF20_RS04235	COG0270	DNA (cytosine-5-)-methyltransferase activity
FDF20_RS04395	COG1598	PFAM Uncharacterised protein family UPF0150
FDF20_RS04410	COG0739	heme binding
FDF20_RS04495	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF20_RS04500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF20_RS04520	COG1279	arginine transmembrane transporter activity
FDF20_RS04525	COG0583	DNA-binding transcription factor activity
FDF20_RS04565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF20_RS04570	COG1388	LysM domain
FDF20_RS04570	COG0741	lytic transglycosylase activity
FDF20_RS04570	COG1388	LysM domain
FDF20_RS04570	COG0741	lytic transglycosylase activity
FDF20_RS04580	COG4174	ABC transporter (Permease)
FDF20_RS04585	COG4239	(ABC) transporter, permease
FDF20_RS04590	COG4172	Belongs to the ABC transporter superfamily
FDF20_RS04610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF20_RS04620	COG5001	Diguanylate cyclase
FDF20_RS04620	COG2203	Gaf domain
FDF20_RS04620	COG3706	GGDEF domain
FDF20_RS04620	COG4251	negative regulation of phosphorylation
FDF20_RS04640	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDF20_RS04640	COG1902	pentaerythritol trinitrate reductase activity
FDF20_RS04655	COG4269	membrane
FDF20_RS04680	COG3209	COG3209 Rhs family protein
FDF20_RS04720	COG1113	amino acid transport
FDF20_RS04730	COG0531	amino acid
FDF20_RS04750	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS04770	COG1113	amino acid transport
FDF20_RS04805	COG0697	spore germination
FDF20_RS04810	COG2721	sulfolactate sulfo-lyase activity
FDF20_RS04815	COG2271	Major facilitator Superfamily
FDF20_RS04820	COG4948	Mandelate Racemase Muconate Lactonizing
FDF20_RS04830	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS04835	COG2186	Transcriptional regulator
FDF20_RS04860	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS04870	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS04875	COG1024	Enoyl-CoA hydratase
FDF20_RS04880	COG2814	Major facilitator Superfamily
FDF20_RS04895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF20_RS04910	COG1262	PFAM Formylglycine-generating sulfatase enzyme
FDF20_RS04965	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
FDF20_RS04970	COG2072	flavoprotein involved in K transport
FDF20_RS04975	COG0300	oxidoreductase activity
FDF20_RS04985	COG1309	transcriptional regulator
FDF20_RS04990	COG1741	Belongs to the pirin family
FDF20_RS05005	COG2072	flavoprotein involved in K transport
FDF20_RS05015	COG2252	PERMEase
FDF20_RS05020	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FDF20_RS05035	COG3038	cytochrome b561
FDF20_RS05045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FDF20_RS05055	COG0527	aspartate kinase activity
FDF20_RS05095	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
FDF20_RS05190	COG1484	DNA-dependent DNA replication
FDF20_RS05235	COG3755	Protein conserved in bacteria
FDF20_RS05490	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDF20_RS05510	COG0582	viral genome integration into host DNA
FDF20_RS05520	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
FDF20_RS05535	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
FDF20_RS05550	COG0667	Aldo Keto reductase
FDF20_RS05560	COG1765	OsmC-like protein
FDF20_RS05575	COG0542	response to heat
FDF20_RS05610	COG2885	chlorophyll binding
FDF20_RS05620	COG0625	glutathione transferase activity
FDF20_RS05625	COG0220	tRNA (guanine-N7-)-methyltransferase activity
FDF20_RS05655	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
FDF20_RS05665	COG0450	alkyl hydroperoxide reductase
FDF20_RS05685	COG2814	Major facilitator Superfamily
FDF20_RS05690	COG3135	benzoate transporter
FDF20_RS05695	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS05700	COG0633	Ferredoxin
FDF20_RS05700	COG0543	2 iron, 2 sulfur cluster binding
FDF20_RS05705	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDF20_RS05710	COG4638	Rieske (2fe-2S)
FDF20_RS05715	COG0583	DNA-binding transcription factor activity
FDF20_RS05725	COG2871	sodium ion transport
FDF20_RS05810	COG1570	exodeoxyribonuclease VII activity
FDF20_RS05845	COG1280	lysine exporter protein (LysE YggA)
FDF20_RS05850	COG1278	Cold shock
FDF20_RS05890	COG2814	Major facilitator Superfamily
FDF20_RS05935	COG0517	IMP dehydrogenase activity
FDF20_RS05935	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
FDF20_RS05940	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
FDF20_RS05950	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
FDF20_RS05955	COG1137	ATPase activity
FDF20_RS05960	COG1538	Outer membrane efflux protein
FDF20_RS05990	COG4122	O-methyltransferase activity
FDF20_RS06000	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
FDF20_RS06015	COG1522	sequence-specific DNA binding
FDF20_RS06020	COG5006	permease, DMT superfamily
FDF20_RS06030	COG1560	Kdo2-lipid A biosynthetic process
FDF20_RS06040	COG2814	Major facilitator Superfamily
FDF20_RS06060	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDF20_RS06130	COG0583	DNA-binding transcription factor activity
FDF20_RS06135	COG1914	H( )-stimulated, divalent metal cation uptake system
FDF20_RS06155	COG4770	biotin carboxylase activity
FDF20_RS06160	COG0038	chloride channel
FDF20_RS06165	COG2831	hemolysin activation secretion protein
FDF20_RS06170	COG3210	domain, Protein
FDF20_RS06185	COG1309	transcriptional regulator
FDF20_RS06195	COG1063	alcohol dehydrogenase
FDF20_RS06210	COG0439	Biotin carboxylase
FDF20_RS06215	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF20_RS06220	COG1733	regulation of RNA biosynthetic process
FDF20_RS06230	COG0864	Transcriptional regulator
FDF20_RS06245	COG1116	anion transmembrane transporter activity
FDF20_RS06365	COG0590	tRNA wobble adenosine to inosine editing
FDF20_RS06370	COG2807	transmembrane transport
FDF20_RS06385	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
FDF20_RS06395	COG0789	Transcriptional regulator
FDF20_RS06410	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF20_RS06430	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
FDF20_RS06455	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS06460	COG0531	amino acid
FDF20_RS06465	COG1760	l-serine dehydratase
FDF20_RS06470	COG2030	dehydratase
FDF20_RS06470	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS06475	COG3396	Phenylacetate-CoA oxygenase
FDF20_RS06480	COG3460	Phenylacetate-CoA oxygenase
FDF20_RS06485	COG3396	Phenylacetate-CoA oxygenase
FDF20_RS06490	COG2151	metal-sulfur cluster biosynthetic enzyme
FDF20_RS06495	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF20_RS06500	COG1024	Enoyl-CoA hydratase
FDF20_RS06505	COG1024	Enoyl-CoA hydratase
FDF20_RS06525	COG0183	Belongs to the thiolase family
FDF20_RS06530	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
FDF20_RS06535	COG3327	negative regulation of DNA-templated transcription, initiation
FDF20_RS06545	COG2050	protein possibly involved in aromatic compounds catabolism
FDF20_RS06590	COG2207	Transcriptional regulator
FDF20_RS06605	COG1804	L-carnitine dehydratase bile acid-inducible protein F
FDF20_RS06610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
FDF20_RS06615	COG2271	Major facilitator Superfamily
FDF20_RS06620	COG0753	catalase activity
FDF20_RS06625	COG3038	cytochrome b561
FDF20_RS06645	COG2267	carboxylic ester hydrolase activity
FDF20_RS06650	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF20_RS06655	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDF20_RS06660	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS06670	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDF20_RS06680	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS06685	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDF20_RS06690	COG0583	DNA-binding transcription factor activity
FDF20_RS06700	COG1414	Transcriptional regulator
FDF20_RS06705	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF20_RS06715	COG1840	ABC-type Fe3 transport system, periplasmic component
FDF20_RS06720	COG3842	ATPase activity
FDF20_RS06735	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
FDF20_RS06740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FDF20_RS06745	COG2814	Major facilitator Superfamily
FDF20_RS06750	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS06765	COG1024	Enoyl-CoA hydratase
FDF20_RS06775	COG2814	Major facilitator Superfamily
FDF20_RS06785	COG0183	Belongs to the thiolase family
FDF20_RS06790	COG1250	3-hydroxyacyl-CoA dehydrogenase
FDF20_RS06795	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS06800	COG1024	Enoyl-CoA hydratase
FDF20_RS06805	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS06810	COG2814	Major facilitator Superfamily
FDF20_RS06815	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDF20_RS06820	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDF20_RS06830	COG2814	Major facilitator Superfamily
FDF20_RS06840	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS06855	COG0583	DNA-binding transcription factor activity
FDF20_RS06865	COG4770	biotin carboxylase activity
FDF20_RS06870	COG1024	Enoyl-CoA hydratase
FDF20_RS06875	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDF20_RS06880	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS06885	COG1309	transcriptional regulator
FDF20_RS06910	COG0583	DNA-binding transcription factor activity
FDF20_RS06955	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS06975	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
FDF20_RS06995	COG0784	Response regulator, receiver
FDF20_RS06995	COG2205	protein histidine kinase activity
FDF20_RS07015	COG0765	amino acid transport
FDF20_RS07020	COG0765	amino acid transport
FDF20_RS07030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDF20_RS07035	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FDF20_RS07050	COG1280	lysine exporter protein (LysE YggA)
FDF20_RS07055	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
FDF20_RS07060	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDF20_RS07065	COG1045	serine acetyltransferase
FDF20_RS07080	COG0583	DNA-binding transcription factor activity
FDF20_RS07085	COG0625	glutathione transferase activity
FDF20_RS07090	COG0625	glutathione transferase activity
FDF20_RS07095	COG0583	DNA-binding transcription factor activity
FDF20_RS07105	COG1346	cytolysis
FDF20_RS07125	COG2814	Major facilitator Superfamily
FDF20_RS07135	COG0583	DNA-binding transcription factor activity
FDF20_RS07145	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
FDF20_RS07150	COG3052	prosthetic group binding
FDF20_RS07170	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
FDF20_RS07190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF20_RS07200	COG1294	oxidase, subunit
FDF20_RS07205	COG1271	oxidase subunit
FDF20_RS07230	COG0477	Major facilitator Superfamily
FDF20_RS07240	COG4521	taurine ABC transporter
FDF20_RS07245	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
FDF20_RS07250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF20_RS07255	COG2175	clavaminate synthase activity
FDF20_RS07265	COG1953	Uracil, thiamine, allantoin
FDF20_RS07275	COG0583	DNA-binding transcription factor activity
FDF20_RS07285	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
FDF20_RS07300	COG0640	Transcriptional regulator
FDF20_RS07305	COG0798	PFAM Bile acid sodium symporter
FDF20_RS07310	COG0583	DNA-binding transcription factor activity
FDF20_RS07325	COG3634	alkyl hydroperoxide reductase activity
FDF20_RS07360	COG1301	dicarboxylic acid transport
FDF20_RS07365	COG0436	Aminotransferase
FDF20_RS07375	COG0386	Belongs to the glutathione peroxidase family
FDF20_RS07415	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDF20_RS07440	COG0012	GTP binding
FDF20_RS07445	COG2011	ABC-type metal ion transport system permease component
FDF20_RS07450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDF20_RS07460	COG1464	Belongs to the NlpA lipoprotein family
FDF20_RS07490	COG0765	amino acid transport
FDF20_RS07495	COG0765	amino acid transport
FDF20_RS07500	COG1126	abc transporter atp-binding protein
FDF20_RS07510	COG1522	sequence-specific DNA binding
FDF20_RS07525	COG1309	transcriptional regulator
FDF20_RS07545	COG0583	DNA-binding transcription factor activity
FDF20_RS07555	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
FDF20_RS07565	COG0697	spore germination
FDF20_RS07595	COG3121	Chaperone
FDF20_RS07600	COG3539	Fimbrial protein
FDF20_RS07625	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
FDF20_RS07625	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
FDF20_RS07670	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
FDF20_RS07680	COG2353	YceI-like domain
FDF20_RS07690	COG3698	Phosphodiester glycosidase
FDF20_RS07705	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
FDF20_RS07710	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDF20_RS07710	COG0506	proline dehydrogenase activity
FDF20_RS07710	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
FDF20_RS07720	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDF20_RS07725	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FDF20_RS07745	COG1132	(ABC) transporter
FDF20_RS07750	COG3122	Protein conserved in bacteria
FDF20_RS07755	COG3619	membrane
FDF20_RS07765	COG0640	Transcriptional regulator
FDF20_RS07775	COG2850	peptidyl-arginine hydroxylation
FDF20_RS07780	COG0424	maF-like protein
FDF20_RS07800	COG0191	fructose-bisphosphate aldolase activity
FDF20_RS07805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDF20_RS07820	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
FDF20_RS07830	COG1192	Involved in chromosome partitioning
FDF20_RS07835	COG1475	DNA binding
FDF20_RS07840	COG0811	peptide transport
FDF20_RS07850	COG1132	(ABC) transporter
FDF20_RS07855	COG1663	tetraacyldisaccharide 4'-kinase activity
FDF20_RS07875	COG0084	hydrolase, TatD family'
FDF20_RS07940	COG0776	regulation of translation
FDF20_RS07970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
FDF20_RS07975	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
FDF20_RS08020	COG0339	signal peptide processing
FDF20_RS08030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FDF20_RS08065	COG0702	epimerase
FDF20_RS08070	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDF20_RS08090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
FDF20_RS08120	COG0316	Belongs to the HesB IscA family
FDF20_RS08125	COG0822	iron-sulfur transferase activity
FDF20_RS08150	COG0776	regulation of translation
FDF20_RS08155	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
FDF20_RS08160	COG2207	Transcriptional regulator
FDF20_RS08165	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDF20_RS08170	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS08175	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS08190	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FDF20_RS08215	COG4264	IucA IucC family
FDF20_RS08225	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDF20_RS08275	COG0406	alpha-ribazole phosphatase activity
FDF20_RS08290	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FDF20_RS08295	COG0730	response to heat
FDF20_RS08315	COG4773	Receptor
FDF20_RS08320	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDF20_RS08335	COG1131	(ABC) transporter
FDF20_RS08340	COG0842	Transport permease protein
FDF20_RS08345	COG0842	Transport permease protein
FDF20_RS08400	COG2226	methyltransferase
FDF20_RS08425	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
FDF20_RS08460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDF20_RS08470	COG0133	tryptophan synthase activity
FDF20_RS08485	COG3706	GGDEF domain
FDF20_RS08500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDF20_RS08505	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
FDF20_RS08510	COG0022	dehydrogenase e1 component
FDF20_RS08515	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDF20_RS08520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDF20_RS08530	COG1063	alcohol dehydrogenase
FDF20_RS08535	COG3781	membrane
FDF20_RS08545	COG3453	Protein conserved in bacteria
FDF20_RS08545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF20_RS08555	COG0730	response to heat
FDF20_RS08570	COG2207	Transcriptional regulator
FDF20_RS08570	COG3708	Transcriptional regulator
FDF20_RS08575	COG1733	regulation of RNA biosynthetic process
FDF20_RS08580	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
FDF20_RS08590	COG2188	Transcriptional regulator
FDF20_RS08605	COG4521	taurine ABC transporter
FDF20_RS08610	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF20_RS08630	COG0477	Major facilitator Superfamily
FDF20_RS08640	COG1027	Aspartate ammonia-lyase
FDF20_RS08655	COG0583	DNA-binding transcription factor activity
FDF20_RS08660	COG0583	DNA-binding transcription factor activity
FDF20_RS08665	COG0183	Belongs to the thiolase family
FDF20_RS08670	COG2031	fatty acid transporter
FDF20_RS08685	COG0583	DNA-binding transcription factor activity
FDF20_RS08705	COG1309	transcriptional regulator
FDF20_RS08715	COG2610	gluconate transmembrane transporter activity
FDF20_RS08720	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS08725	COG2207	Transcriptional regulator
FDF20_RS08740	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS08750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF20_RS08765	COG0543	2 iron, 2 sulfur cluster binding
FDF20_RS08765	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF20_RS08770	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
FDF20_RS08775	COG4638	Rieske (2fe-2S)
FDF20_RS08785	COG0725	ABC transporter, periplasmic molybdate-binding protein
FDF20_RS08790	COG4149	molybdate abc transporter
FDF20_RS08795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
FDF20_RS08800	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS08805	COG3433	isochorismatase activity
FDF20_RS08805	COG1535	isochorismatase
FDF20_RS08870	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDF20_RS08885	COG0753	catalase activity
FDF20_RS08895	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
FDF20_RS08920	COG3539	Fimbrial protein
FDF20_RS09030	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
FDF20_RS09035	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF20_RS09040	COG0745	RESPONSE REGULATOR receiver
FDF20_RS09045	COG2205	protein histidine kinase activity
FDF20_RS09055	COG2207	Transcriptional regulator
FDF20_RS09065	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS09080	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
FDF20_RS09135	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
FDF20_RS09185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
FDF20_RS09205	COG1120	ATPase activity
FDF20_RS09210	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDF20_RS09220	COG1064	alcohol dehydrogenase
FDF20_RS09235	COG2207	Transcriptional regulator
FDF20_RS09240	COG2084	Dehydrogenase
FDF20_RS09250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDF20_RS09255	COG0583	DNA-binding transcription factor activity
FDF20_RS09265	COG0129	dihydroxy-acid dehydratase activity
FDF20_RS09270	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS09285	COG1566	PFAM secretion protein HlyD family protein
FDF20_RS09305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
FDF20_RS09335	COG0583	DNA-binding transcription factor activity
FDF20_RS09350	COG2188	Transcriptional regulator
FDF20_RS09445	COG0318	PFAM AMP-dependent synthetase and ligase
FDF20_RS09455	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS09465	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS09475	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS09480	COG0583	DNA-binding transcription factor activity
FDF20_RS09485	COG1309	transcriptional regulator
FDF20_RS09520	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FDF20_RS09530	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDF20_RS09530	COG1902	pentaerythritol trinitrate reductase activity
FDF20_RS09545	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS09565	COG2186	Transcriptional regulator
FDF20_RS09575	COG0583	DNA-binding transcription factor activity
FDF20_RS09580	COG4948	Mandelate Racemase Muconate Lactonizing
FDF20_RS09585	COG4829	muconolactone delta-isomerase
FDF20_RS09595	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDF20_RS09600	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDF20_RS09605	COG0183	Belongs to the thiolase family
FDF20_RS09610	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
FDF20_RS09620	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS09630	COG3733	amine oxidase
FDF20_RS09640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF20_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS09660	COG4638	Rieske (2fe-2S)
FDF20_RS09680	COG0154	amidase activity
FDF20_RS09690	COG2814	Major facilitator Superfamily
FDF20_RS09715	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS09720	COG0583	DNA-binding transcription factor activity
FDF20_RS09725	COG1414	Transcriptional regulator
FDF20_RS09740	COG2391	methyltransferase activity
FDF20_RS09750	COG4993	Dehydrogenase
FDF20_RS09755	COG3659	wide pore channel activity
FDF20_RS09760	COG3420	alginic acid biosynthetic process
FDF20_RS09765	COG0710	3-dehydroquinate dehydratase activity
FDF20_RS09770	COG3485	protocatechuate 3,4-dioxygenase
FDF20_RS09775	COG3485	protocatechuate 3,4-dioxygenase
FDF20_RS09780	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
FDF20_RS09785	COG2271	Major facilitator Superfamily
FDF20_RS09790	COG0596	Alpha beta hydrolase
FDF20_RS09795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FDF20_RS09800	COG0183	Belongs to the thiolase family
FDF20_RS09805	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
FDF20_RS09810	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
FDF20_RS09820	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
FDF20_RS09825	COG2323	membrane
FDF20_RS09870	COG1902	pentaerythritol trinitrate reductase activity
FDF20_RS09870	COG0446	pyridine nucleotide-disulphide oxidoreductase
FDF20_RS09895	COG0542	response to heat
FDF20_RS09900	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
FDF20_RS09930	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDF20_RS09935	COG0569	domain protein
FDF20_RS09940	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FDF20_RS09955	COG4774	siderophore transport
FDF20_RS09960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FDF20_RS09970	COG1585	Membrane protein implicated in regulation of membrane protease activity
FDF20_RS09985	COG1294	oxidase, subunit
FDF20_RS09990	COG4890	Cyd operon protein YbgT
FDF20_RS10005	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
FDF20_RS10015	COG0552	protein localization to endoplasmic reticulum
FDF20_RS10045	COG0517	IMP dehydrogenase activity
FDF20_RS10045	COG0516	GMP reductase activity
FDF20_RS10050	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDF20_RS10055	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
FDF20_RS10065	COG0583	DNA-binding transcription factor activity
FDF20_RS10070	COG0024	Methionine aminopeptidase
FDF20_RS10100	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
FDF20_RS10100	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FDF20_RS10105	COG1105	Belongs to the carbohydrate kinase PfkB family
FDF20_RS10110	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
FDF20_RS10110	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDF20_RS10110	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
FDF20_RS10130	COG5001	Diguanylate cyclase
FDF20_RS10130	COG3300	MHYT domain
FDF20_RS10145	COG2135	peptidase activity
FDF20_RS10150	COG0659	secondary active sulfate transmembrane transporter activity
FDF20_RS10165	COG1113	amino acid transport
FDF20_RS10175	COG1522	sequence-specific DNA binding
FDF20_RS10200	COG1011	Hydrolase
FDF20_RS10205	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
FDF20_RS10215	COG2137	regulation of response to DNA damage stimulus
FDF20_RS10230	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
FDF20_RS10265	COG0575	Belongs to the CDS family
FDF20_RS10270	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
FDF20_RS10295	COG3852	Histidine kinase
FDF20_RS10300	COG2204	response regulator
FDF20_RS10360	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDF20_RS10365	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
FDF20_RS10385	COG0697	spore germination
FDF20_RS10390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF20_RS10405	COG0521	Mo-molybdopterin cofactor biosynthetic process
FDF20_RS10405	COG0315	cyclic pyranopterin monophosphate synthase activity
FDF20_RS10420	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
FDF20_RS10425	COG0243	molybdopterin cofactor binding
FDF20_RS10435	COG0243	molybdopterin cofactor binding
FDF20_RS10440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF20_RS10445	COG2146	nitrite reductase [NAD(P)H] activity
FDF20_RS10445	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF20_RS10455	COG0745	RESPONSE REGULATOR receiver
FDF20_RS10460	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDF20_RS10460	COG1116	anion transmembrane transporter activity
FDF20_RS10480	COG0511	ligase activity, forming carbon-carbon bonds
FDF20_RS10495	COG2814	Major facilitator Superfamily
FDF20_RS10535	COG3293	Transposase
FDF20_RS10540	COG1063	alcohol dehydrogenase
FDF20_RS10550	COG3179	chitinase
FDF20_RS10590	COG0739	heme binding
FDF20_RS10590	COG0741	lytic transglycosylase activity
FDF20_RS10590	COG1196	nuclear chromosome segregation
FDF20_RS10600	COG1598	PFAM Uncharacterised protein family UPF0150
FDF20_RS10795	COG3620	sequence-specific DNA binding
FDF20_RS10880	COG0069	glutamate synthase activity
FDF20_RS10920	COG1454	alcohol dehydrogenase
FDF20_RS10925	COG0824	Thioesterase
FDF20_RS10950	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
FDF20_RS10955	COG2030	dehydratase
FDF20_RS10965	COG0183	Belongs to the thiolase family
FDF20_RS10975	COG0583	DNA-binding transcription factor activity
FDF20_RS10980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FDF20_RS10990	COG1522	sequence-specific DNA binding
FDF20_RS10995	COG3135	benzoate transporter
FDF20_RS11005	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FDF20_RS11020	COG0589	response to stress
FDF20_RS11025	COG0488	(ABC) transporter
FDF20_RS11050	COG4773	Receptor
FDF20_RS11080	COG0668	transmembrane transport
FDF20_RS11090	COG1309	transcriptional regulator
FDF20_RS11110	COG1605	Chorismate mutase
FDF20_RS11120	COG4221	oxidoreductase activity
FDF20_RS11150	COG0308	aminopeptidase N
FDF20_RS11175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FDF20_RS11180	COG1454	alcohol dehydrogenase
FDF20_RS11200	COG0531	amino acid
FDF20_RS11205	COG4303	Ethanolamine ammonia lyase large subunit
FDF20_RS11210	COG4302	ethanolamine ammonia-lyase activity
FDF20_RS11215	COG0519	Catalyzes the synthesis of GMP from XMP
FDF20_RS11215	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDF20_RS11220	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
FDF20_RS11245	COG0697	spore germination
FDF20_RS11250	COG1923	regulation of RNA biosynthetic process
FDF20_RS11260	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
FDF20_RS11265	COG0802	atpase or kinase
FDF20_RS11285	COG1187	pseudouridine synthase activity
FDF20_RS11300	COG0583	DNA-binding transcription factor activity
FDF20_RS11315	COG2814	Major facilitator Superfamily
FDF20_RS11320	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FDF20_RS11350	COG0729	surface antigen
FDF20_RS11370	COG0174	glutamine synthetase
FDF20_RS11375	COG0745	RESPONSE REGULATOR receiver
FDF20_RS11380	COG2205	protein histidine kinase activity
FDF20_RS11390	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
FDF20_RS11395	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
FDF20_RS11420	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF20_RS11425	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDF20_RS11430	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS11445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDF20_RS11450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF20_RS11470	COG0583	DNA-binding transcription factor activity
FDF20_RS11490	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDF20_RS11500	COG3658	cytochrome
FDF20_RS11505	COG1215	transferase activity, transferring glycosyl groups
FDF20_RS11510	COG1649	PFAM Uncharacterised BCR, COG1649
FDF20_RS11510	COG0726	polysaccharide deacetylase
FDF20_RS11535	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
FDF20_RS11540	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
FDF20_RS11550	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
FDF20_RS11575	COG0305	Participates in initiation and elongation during chromosome replication
FDF20_RS11580	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FDF20_RS11590	COG1305	Transglutaminase-like
FDF20_RS11630	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
FDF20_RS11635	COG0138	bifunctional purine biosynthesis protein purh
FDF20_RS11640	COG0151	Belongs to the GarS family
FDF20_RS11645	COG1464	Belongs to the NlpA lipoprotein family
FDF20_RS11650	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
FDF20_RS11655	COG2011	ABC-type metal ion transport system permease component
FDF20_RS11660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
FDF20_RS11670	COG1301	dicarboxylic acid transport
FDF20_RS11700	COG1794	racemase activity, acting on amino acids and derivatives
FDF20_RS11720	COG0745	RESPONSE REGULATOR receiver
FDF20_RS11725	COG0642	Histidine kinase
FDF20_RS11730	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDF20_RS11740	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FDF20_RS11780	COG2351	hydroxyisourate hydrolase activity
FDF20_RS11790	COG3008	intermembrane lipid transfer
FDF20_RS11790	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
FDF20_RS11795	COG2995	paraquat-inducible protein a
FDF20_RS11810	COG2985	domain, Protein
FDF20_RS11835	COG0477	Major facilitator Superfamily
FDF20_RS11885	COG2186	Transcriptional regulator
FDF20_RS11895	COG0786	glutamate:sodium symporter activity
FDF20_RS11900	COG3243	poly(R)-hydroxyalkanoic acid synthase
FDF20_RS11925	COG3111	PFAM Bacterial OB fold (BOF) protein
FDF20_RS12105	COG1610	YqeY-like protein
FDF20_RS12110	COG4783	chaperone-mediated protein folding
FDF20_RS12135	COG1286	toxin biosynthetic process
FDF20_RS12165	COG0778	Nitroreductase
FDF20_RS12175	COG0513	Belongs to the DEAD box helicase family
FDF20_RS12195	COG2363	Small membrane protein
FDF20_RS12225	COG1234	tRNA 3'-trailer cleavage
FDF20_RS12230	COG2195	Cleaves the N-terminal amino acid of tripeptides
FDF20_RS12240	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
FDF20_RS12250	COG2819	hydrolase of the alpha beta superfamily
FDF20_RS12255	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS12260	COG1301	dicarboxylic acid transport
FDF20_RS12270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FDF20_RS12275	COG3139	Protein of unknown function (DUF1315)
FDF20_RS12280	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
FDF20_RS12285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FDF20_RS12295	COG0494	nUDIX hydrolase
FDF20_RS12305	COG0642	Histidine kinase
FDF20_RS12320	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDF20_RS12330	COG1720	tRNA m6t6A37 methyltransferase activity
FDF20_RS12345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF20_RS12350	COG0826	peptidase U32
FDF20_RS12355	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
FDF20_RS12365	COG4598	ABC transporter
FDF20_RS12370	COG4160	amino acid transport
FDF20_RS12375	COG4215	(ABC) transporter
FDF20_RS12390	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF20_RS12430	COG1131	(ABC) transporter
FDF20_RS12435	COG0842	Transport permease protein
FDF20_RS12450	COG0772	Belongs to the SEDS family
FDF20_RS12455	COG2951	lytic endotransglycosylase activity
FDF20_RS12480	COG2207	Transcriptional regulator
FDF20_RS12495	COG0052	Belongs to the universal ribosomal protein uS2 family
FDF20_RS12500	COG0024	Methionine aminopeptidase
FDF20_RS12510	COG2223	nitrite transmembrane transporter activity
FDF20_RS12520	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDF20_RS12525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
FDF20_RS12530	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS12545	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FDF20_RS12550	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FDF20_RS12555	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDF20_RS12575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDF20_RS12580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FDF20_RS12585	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
FDF20_RS12620	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
FDF20_RS12630	COG0174	glutamine synthetase
FDF20_RS12645	COG0512	Glutamine amidotransferase of anthranilate synthase
FDF20_RS12650	COG0308	aminopeptidase N
FDF20_RS12680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
FDF20_RS12690	COG0302	gtp cyclohydrolase
FDF20_RS12710	COG3739	integral membrane protein
FDF20_RS12725	COG1169	isochorismate synthase
FDF20_RS12735	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
FDF20_RS12740	COG1132	(ABC) transporter
FDF20_RS12745	COG1132	(ABC) transporter
FDF20_RS12760	COG1535	isochorismatase
FDF20_RS12760	COG3433	isochorismatase activity
FDF20_RS12765	COG1021	2,3-dihydroxybenzoate-AMP ligase
FDF20_RS12770	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF20_RS12780	COG4774	siderophore transport
FDF20_RS12785	COG4607	ABC-type enterochelin transport system periplasmic component
FDF20_RS12790	COG4604	ABC transporter, ATP-binding protein
FDF20_RS12795	COG4605	iron ion homeostasis
FDF20_RS12800	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
FDF20_RS12805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF20_RS12820	COG2964	Protein conserved in bacteria
FDF20_RS12830	COG1741	Belongs to the pirin family
FDF20_RS12860	COG2130	NADP-dependent
FDF20_RS12870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
FDF20_RS12880	COG0596	Alpha beta hydrolase
FDF20_RS12895	COG0583	DNA-binding transcription factor activity
FDF20_RS12900	COG1335	isochorismatase
FDF20_RS12940	COG2879	small protein
FDF20_RS12945	COG1966	Carbon starvation protein
FDF20_RS12965	COG4943	cyclic-guanylate-specific phosphodiesterase activity
FDF20_RS12990	COG1067	ATP-dependent peptidase activity
FDF20_RS12995	COG0583	DNA-binding transcription factor activity
FDF20_RS13020	COG1686	Belongs to the peptidase S11 family
FDF20_RS13025	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
FDF20_RS13060	COG0616	signal peptide processing
FDF20_RS13065	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
FDF20_RS13075	COG0573	inorganic phosphate transmembrane transporter activity
FDF20_RS13080	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
FDF20_RS13085	COG1113	amino acid transport
FDF20_RS13090	COG3961	Belongs to the TPP enzyme family
FDF20_RS13095	COG1522	sequence-specific DNA binding
FDF20_RS13105	COG0076	glutamate decarboxylase activity
FDF20_RS13110	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDF20_RS13125	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF20_RS13135	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF20_RS13170	COG0352	thiamine-phosphate diphosphorylase activity
FDF20_RS13195	COG0612	Peptidase, M16
FDF20_RS13205	COG1823	symporter activity
FDF20_RS13210	COG0583	DNA-binding transcription factor activity
FDF20_RS13215	COG0477	Major facilitator Superfamily
FDF20_RS13240	COG0582	viral genome integration into host DNA
FDF20_RS13515	COG3646	Phage regulatory protein
FDF20_RS13515	COG3645	SOS response
FDF20_RS13585	COG1187	pseudouridine synthase activity
FDF20_RS13600	COG1686	Belongs to the peptidase S11 family
FDF20_RS13605	COG1252	NADH dehydrogenase
FDF20_RS13615	COG0415	Belongs to the DNA photolyase family
FDF20_RS13630	COG1215	transferase activity, transferring glycosyl groups
FDF20_RS13660	COG2070	2-Nitropropane dioxygenase
FDF20_RS13715	COG0556	nucleotide-excision repair
FDF20_RS13735	COG0436	Aminotransferase
FDF20_RS13745	COG0443	Heat shock 70 kDa protein
FDF20_RS13775	COG4221	oxidoreductase activity
FDF20_RS13785	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
FDF20_RS13790	COG1381	Involved in DNA repair and RecF pathway recombination
FDF20_RS13800	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
FDF20_RS13815	COG0681	Belongs to the peptidase S26 family
FDF20_RS13825	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FDF20_RS13835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FDF20_RS13855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
FDF20_RS13860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FDF20_RS13865	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
FDF20_RS13875	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
FDF20_RS13880	COG4208	sulfate ABC transporter
FDF20_RS13885	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
FDF20_RS13890	COG0583	DNA-binding transcription factor activity
FDF20_RS13895	COG4625	pathogenesis
FDF20_RS13910	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
FDF20_RS13925	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FDF20_RS13935	COG1051	belongs to the nudix hydrolase family
FDF20_RS13935	COG1056	cytidyltransferase-related domain
FDF20_RS13940	COG1024	Enoyl-CoA hydratase
FDF20_RS13950	COG2814	Major facilitator Superfamily
FDF20_RS13955	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FDF20_RS13955	COG0047	phosphoribosylformylglycinamidine synthase activity
FDF20_RS13975	COG1473	amidohydrolase
FDF20_RS13980	COG0824	Thioesterase
FDF20_RS14000	COG0823	Involved in the tonB-independent uptake of proteins
FDF20_RS14020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FDF20_RS14055	COG0628	permease
FDF20_RS14065	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
FDF20_RS14070	COG0596	Alpha beta hydrolase
FDF20_RS14075	COG0616	signal peptide processing
FDF20_RS14075	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
FDF20_RS14085	COG2333	competence protein COMEC
FDF20_RS14085	COG0658	competence protein
FDF20_RS14090	COG1136	(ABC) transporter
FDF20_RS14095	COG4591	ABC-type transport system involved in lipoprotein release permease component
FDF20_RS14125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF20_RS14145	COG0463	Glycosyl transferase, family 2
FDF20_RS14185	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDF20_RS14190	COG1280	lysine exporter protein (LysE YggA)
FDF20_RS14200	COG0019	diaminopimelate decarboxylase activity
FDF20_RS14210	COG1113	amino acid transport
FDF20_RS14225	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
FDF20_RS14235	COG3339	Conserved Protein
FDF20_RS14240	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
FDF20_RS14245	COG0243	molybdopterin cofactor binding
FDF20_RS14250	COG1929	Belongs to the glycerate kinase type-1 family
FDF20_RS14265	COG0778	Nitroreductase
FDF20_RS14290	COG3811	Belongs to the UPF0386 family
FDF20_RS14300	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF20_RS14315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FDF20_RS14340	COG0741	lytic transglycosylase activity
FDF20_RS14360	COG0584	glycerophosphoryl diester phosphodiesterase
FDF20_RS14390	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
FDF20_RS14395	COG1597	lipid kinase activity
FDF20_RS14410	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
FDF20_RS14415	COG0477	Major facilitator Superfamily
FDF20_RS14465	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FDF20_RS14470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FDF20_RS14495	COG0505	Belongs to the CarA family
FDF20_RS14510	COG1309	transcriptional regulator
FDF20_RS14515	COG0251	oxidation-reduction process
FDF20_RS14525	COG0589	response to stress
FDF20_RS14615	COG2321	neutral zinc metallopeptidase
FDF20_RS14620	COG2354	Protein conserved in bacteria
FDF20_RS14640	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FDF20_RS14665	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FDF20_RS14670	COG1053	succinate dehydrogenase
FDF20_RS14675	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
FDF20_RS14680	COG2009	succinate dehydrogenase
FDF20_RS14715	COG2921	Belongs to the UPF0250 family
FDF20_RS14720	COG0321	lipoyl(octanoyl) transferase activity
FDF20_RS14735	COG0531	amino acid
FDF20_RS14745	COG1733	regulation of RNA biosynthetic process
FDF20_RS14750	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FDF20_RS14755	COG1648	precorrin-2 dehydrogenase activity
FDF20_RS14755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
FDF20_RS14770	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
FDF20_RS14800	COG0671	phosphoesterase, PA-phosphatase related
FDF20_RS14805	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF20_RS14815	COG1538	Outer membrane efflux protein
FDF20_RS14820	COG0393	Putative heavy-metal-binding
FDF20_RS14825	COG0393	Putative heavy-metal-binding
FDF20_RS14835	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS14845	COG0525	valine-tRNA ligase activity
FDF20_RS14865	COG0583	DNA-binding transcription factor activity
FDF20_RS14875	COG0004	ammonium transporteR
FDF20_RS14885	COG0642	Histidine kinase
FDF20_RS14890	COG0745	RESPONSE REGULATOR receiver
FDF20_RS14895	COG2194	sulfuric ester hydrolase activity
FDF20_RS14915	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDF20_RS14930	COG2315	Protein conserved in bacteria
FDF20_RS14935	COG0142	geranyltranstransferase activity
FDF20_RS14940	COG2828	Protein conserved in bacteria
FDF20_RS14950	COG1113	amino acid transport
FDF20_RS14970	COG2207	Transcriptional regulator
FDF20_RS15005	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF20_RS15015	COG0560	Phosphoserine phosphatase
FDF20_RS15025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
FDF20_RS15035	COG1530	ribonuclease E activity
FDF20_RS15040	COG0424	maF-like protein
FDF20_RS15045	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
FDF20_RS15050	COG1792	Involved in formation and maintenance of cell shape
FDF20_RS15055	COG1077	Cell shape determining protein MreB Mrl
FDF20_RS15060	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDF20_RS15070	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
FDF20_RS15115	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
FDF20_RS15120	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FDF20_RS15125	COG1752	Esterase of the alpha-beta hydrolase superfamily
FDF20_RS15130	COG1115	amino acid carrier protein
FDF20_RS15150	COG2814	Major facilitator Superfamily
FDF20_RS15155	COG1289	transmembrane transporter activity
FDF20_RS15165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
FDF20_RS15205	COG1376	ErfK ybiS ycfS ynhG family protein
FDF20_RS15210	COG2832	Protein of unknown function (DUF454)
FDF20_RS15220	COG5510	response to toxic substance
FDF20_RS15240	COG0840	transmembrane signaling receptor activity
FDF20_RS15280	COG3422	double-strand break repair
FDF20_RS15285	COG2824	Alkylphosphonate utilization operon protein PhnA
FDF20_RS15290	COG3189	MarR family transcriptional regulator
FDF20_RS15300	COG0354	folic acid binding
FDF20_RS15305	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDF20_RS15320	COG1902	pentaerythritol trinitrate reductase activity
FDF20_RS15325	COG4772	TonB-dependent receptor
FDF20_RS15330	COG2094	Belongs to the DNA glycosylase MPG family
FDF20_RS15355	COG1217	gtp-binding protein TYPA
FDF20_RS15360	COG2233	PERMEase
FDF20_RS15370	COG0833	amino acid
FDF20_RS15375	COG1690	Belongs to the RtcB family
FDF20_RS15380	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
FDF20_RS15380	COG2885	chlorophyll binding
FDF20_RS15390	COG0183	Belongs to the thiolase family
FDF20_RS15410	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
FDF20_RS15430	COG2207	Transcriptional regulator
FDF20_RS15435	COG0183	Belongs to the thiolase family
FDF20_RS15455	COG2153	protein acetylation
FDF20_RS15465	COG1272	protein, Hemolysin III
FDF20_RS15470	COG0477	Major facilitator Superfamily
FDF20_RS15485	COG0450	alkyl hydroperoxide reductase
FDF20_RS15505	COG0285	dihydrofolate synthase activity
FDF20_RS15555	COG2096	Adenosyltransferase
FDF20_RS15575	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
FDF20_RS15580	COG0745	RESPONSE REGULATOR receiver
FDF20_RS15585	COG2205	protein histidine kinase activity
FDF20_RS15595	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS15600	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS15650	COG1442	glycosyl transferase family 8
FDF20_RS15670	COG0438	transferase activity, transferring glycosyl groups
FDF20_RS15680	COG0438	transferase activity, transferring glycosyl groups
FDF20_RS15685	COG0726	polysaccharide deacetylase
FDF20_RS15700	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
FDF20_RS15705	COG2205	protein histidine kinase activity
FDF20_RS15745	COG1862	Preprotein translocase
FDF20_RS15755	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
FDF20_RS15770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
FDF20_RS15780	COG3781	membrane
FDF20_RS15785	COG0613	PHP domain protein
FDF20_RS15795	COG2350	Protein conserved in bacteria
FDF20_RS15825	COG1607	acyl-coa hydrolase
FDF20_RS15885	COG2199	diguanylate cyclase activity
FDF20_RS15895	COG1408	metallophosphoesterase
FDF20_RS15900	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
FDF20_RS15910	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FDF20_RS15930	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
FDF20_RS15935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
FDF20_RS15950	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
FDF20_RS15960	COG2969	positive regulation of protein catabolic process
FDF20_RS16000	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS16005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FDF20_RS16020	COG1309	transcriptional regulator
FDF20_RS16025	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS16075	COG1183	phosphatidylcholine synthase activity
FDF20_RS16080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
FDF20_RS16110	COG1196	nuclear chromosome segregation
FDF20_RS16110	COG0741	lytic transglycosylase activity
FDF20_RS16110	COG0739	heme binding
FDF20_RS16120	COG1702	phosphate starvation-inducible protein PhoH
FDF20_RS16155	COG1295	ribonuclease BN
FDF20_RS16160	COG0697	spore germination
FDF20_RS16165	COG2169	Transcriptional regulator
FDF20_RS16170	COG0179	Fumarylacetoacetate (FAA) hydrolase
FDF20_RS16220	COG0557	exoribonuclease II activity
FDF20_RS16225	COG0339	signal peptide processing
FDF20_RS16230	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
FDF20_RS16260	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
FDF20_RS16265	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS16420	COG0626	cystathionine gamma-synthase activity
FDF20_RS16425	COG0433	COG0433 Predicted ATPase
FDF20_RS16435	COG1017	nitric oxide dioxygenase activity
FDF20_RS16435	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
FDF20_RS16440	COG1959	2 iron, 2 sulfur cluster binding
FDF20_RS16455	COG1301	dicarboxylic acid transport
FDF20_RS16460	COG1946	Acyl-CoA thioesterase
FDF20_RS16480	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FDF20_RS16485	COG1040	competence protein
FDF20_RS16490	COG0494	nUDIX hydrolase
FDF20_RS16500	COG0598	Magnesium transport protein CorA
FDF20_RS16510	COG2854	intermembrane phospholipid transfer
FDF20_RS16520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
FDF20_RS16525	COG1127	ABC transporter
FDF20_RS16535	COG0513	Belongs to the DEAD box helicase family
FDF20_RS16555	COG0408	coproporphyrinogen oxidase activity
FDF20_RS16570	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS16580	COG1983	PspC domain protein
FDF20_RS16585	COG0517	IMP dehydrogenase activity
FDF20_RS16635	COG0583	DNA-binding transcription factor activity
FDF20_RS16675	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS16685	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
FDF20_RS16690	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FDF20_RS16695	COG0833	amino acid
FDF20_RS16725	COG1192	Involved in chromosome partitioning
FDF20_RS16730	COG0628	permease
FDF20_RS16740	COG1289	transmembrane transporter activity
FDF20_RS16765	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF20_RS16770	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
FDF20_RS16780	COG0277	FAD linked oxidase domain protein
FDF20_RS16785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FDF20_RS16810	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
FDF20_RS16815	COG5380	lipid catabolic process
FDF20_RS16835	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
FDF20_RS16885	COG0194	GDP metabolic process
FDF20_RS16900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FDF20_RS16920	COG3307	-O-antigen
FDF20_RS16935	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
FDF20_RS16940	COG1704	LemA family
FDF20_RS16950	COG0493	'glutamate synthase
FDF20_RS16955	COG0069	glutamate synthase activity
FDF20_RS16955	COG0070	glutamate synthase
FDF20_RS16955	COG0067	glutamate synthase
FDF20_RS17005	COG2226	methyltransferase
FDF20_RS17020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FDF20_RS17025	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
FDF20_RS17070	COG0833	amino acid
FDF20_RS17155	COG0488	(ABC) transporter
FDF20_RS17160	COG2873	o-acetylhomoserine
FDF20_RS17165	COG4221	oxidoreductase activity
FDF20_RS17170	COG0659	secondary active sulfate transmembrane transporter activity
FDF20_RS17195	COG0427	acetyl-CoA hydrolase
FDF20_RS17225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
FDF20_RS17255	COG2329	Antibiotic biosynthesis monooxygenase
FDF20_RS17270	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
FDF20_RS17345	COG2249	NAD(P)H dehydrogenase (quinone) activity
FDF20_RS17355	COG1733	regulation of RNA biosynthetic process
FDF20_RS17390	COG0667	Aldo Keto reductase
FDF20_RS17410	COG0583	DNA-binding transcription factor activity
FDF20_RS17415	COG2814	Major facilitator Superfamily
FDF20_RS17445	COG1335	isochorismatase
FDF20_RS17455	COG1012	belongs to the aldehyde dehydrogenase family
FDF20_RS17460	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
FDF20_RS17470	COG1113	amino acid transport
FDF20_RS17480	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FDF20_RS17495	COG2814	Major facilitator Superfamily
FDF20_RS17505	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FDF20_RS17505	COG0351	phosphomethylpyrimidine kinase
FDF20_RS17505	COG0352	thiamine-phosphate diphosphorylase activity
FDF20_RS17525	COG1309	transcriptional regulator
FDF20_RS17530	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FDF20_RS17550	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
FDF20_RS17560	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FDF20_RS17565	COG3162	membrane
FDF20_RS17570	COG2198	Histidine kinase
FDF20_RS17570	COG0784	Response regulator, receiver
FDF20_RS17570	COG2205	protein histidine kinase activity
FDF20_RS17595	COG1522	sequence-specific DNA binding
FDF20_RS17600	COG1335	isochorismatase
FDF20_RS17605	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDF20_RS17615	COG0668	transmembrane transport
FDF20_RS17620	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FDF20_RS17625	COG1519	Transferase
FDF20_RS17630	COG1902	pentaerythritol trinitrate reductase activity
FDF20_RS17650	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
FDF20_RS17675	COG0426	domain, Protein
FDF20_RS17675	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
FDF20_RS17680	COG4774	siderophore transport
FDF20_RS17685	COG2119	membrane
FDF20_RS17695	COG0508	dehydrogenase complex catalyzes the overall conversion of
FDF20_RS17705	COG4942	peptidase
FDF20_RS17720	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FDF20_RS17730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
FDF20_RS17750	COG0189	ligase activity
FDF20_RS17770	COG0708	Exodeoxyribonuclease III
FDF20_RS17775	COG1393	Belongs to the ArsC family
FDF20_RS17790	COG3706	GGDEF domain
FDF20_RS17825	COG2351	hydroxyisourate hydrolase activity
FDF20_RS17830	COG2233	PERMEase
FDF20_RS17840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
FDF20_RS17850	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
FDF20_RS17855	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS17875	COG3150	esterase
FDF20_RS17895	COG2826	transposase and inactivated derivatives, IS30 family
FDF20_RS17915	COG0673	inositol 2-dehydrogenase activity
FDF20_RS17920	COG1324	tolerance protein
FDF20_RS17950	COG2826	transposase and inactivated derivatives, IS30 family
FDF20_RS17975	COG2918	glutathione biosynthetic process
FDF20_RS17990	COG2733	membrane
FDF20_RS17995	COG0436	Aminotransferase
FDF20_RS18000	COG0534	Mate efflux family protein
FDF20_RS18060	COG0753	catalase activity
FDF20_RS18110	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
FDF20_RS18115	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
FDF20_RS18125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FDF20_RS18130	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
FDF20_RS18145	COG0010	Belongs to the arginase family
FDF20_RS18185	COG0523	cobalamin synthesis protein
FDF20_RS18195	COG1113	amino acid transport
FDF20_RS18205	COG0625	glutathione transferase activity
FDF20_RS18225	COG1683	Conserved Protein
FDF20_RS18230	COG0534	Mate efflux family protein
FDF20_RS18235	COG0385	Bile acid
FDF20_RS18240	COG1335	isochorismatase
FDF20_RS18245	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF20_RS18270	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
FDF20_RS18275	COG2133	pyrroloquinoline quinone binding
FDF20_RS18280	COG2983	Belongs to the UPF0260 family
FDF20_RS18290	COG0400	carboxylic ester hydrolase activity
FDF20_RS18300	COG1194	a g-specific adenine glycosylase
FDF20_RS18315	COG2818	Glycosylase
FDF20_RS18320	COG1064	alcohol dehydrogenase
FDF20_RS18325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF20_RS18340	COG0583	DNA-binding transcription factor activity
FDF20_RS18345	COG0656	L-ascorbic acid biosynthetic process
FDF20_RS18350	COG2814	Major facilitator Superfamily
FDF20_RS18385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
FDF20_RS18400	COG2233	PERMEase
FDF20_RS18440	COG0733	neurotransmitter:sodium symporter activity
FDF20_RS18485	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
FDF20_RS18490	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
FDF20_RS18495	COG0596	Alpha beta hydrolase
FDF20_RS18520	COG0488	(ABC) transporter
FDF20_RS18525	COG0586	Pfam SNARE associated Golgi protein
FDF20_RS18535	COG0187	DNA topoisomerase II activity
FDF20_RS18545	COG0592	DNA-directed DNA polymerase activity
FDF20_RS18570	COG0706	membrane insertase activity
FDF20_RS18585	COG1230	cation diffusion facilitator family transporter
FDF20_RS18590	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
FDF20_RS18605	COG0402	S-adenosylhomocysteine deaminase activity
FDF20_RS18615	COG0754	glutathionylspermidine amidase activity
FDF20_RS18625	COG0861	Integral membrane protein TerC family
FDF20_RS18630	COG0671	phosphoesterase, PA-phosphatase related
FDF20_RS18660	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FDF20_RS18665	COG2951	lytic endotransglycosylase activity
FDF20_RS18715	COG0657	acetylesterase activity
FDF20_RS18720	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FDF20_RS18760	COG1047	Peptidyl-prolyl cis-trans
FDF20_RS18770	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
FDF20_RS18775	COG0196	riboflavin kinase activity
FDF20_RS18785	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FDF20_RS18790	COG1309	transcriptional regulator
FDF20_RS18795	COG1116	anion transmembrane transporter activity
FDF20_RS18800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FDF20_RS18805	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
FDF20_RS18810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDF20_RS18815	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FDF20_RS18835	COG1028	Short-chain dehydrogenase reductase Sdr
FDF20_RS18840	COG0546	phosphoglycolate phosphatase activity
FDF20_RS18895	COG3023	N-Acetylmuramoyl-L-alanine amidase
FDF20_RS18900	COG0728	peptidoglycan biosynthetic process
FDF20_RS18930	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
FDF20_RS18935	COG1086	Polysaccharide biosynthesis protein
FDF20_RS18940	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
FDF20_RS18945	COG1083	cytidylyl-transferase
FDF20_RS18950	COG3980	spore coat polysaccharide biosynthesis protein
FDF20_RS18960	COG2089	acid synthase
FDF20_RS18970	COG3562	capsule polysaccharide
FDF20_RS18980	COG1216	Glycosyl transferase, family 2
FDF20_RS18985	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FDF20_RS18990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
FDF20_RS19005	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FDF20_RS19010	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDF20_RS19020	COG2186	Transcriptional regulator
FDF20_RS19030	COG0277	FAD linked oxidase domain protein
FDF20_RS19035	COG1448	Aminotransferase
FDF20_RS19045	COG1802	Transcriptional regulator
FDF20_RS19060	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FDF20_RS19110	COG0564	pseudouridine synthase activity
FDF20_RS19150	COG0251	oxidation-reduction process
FDF20_RS19155	COG1113	amino acid transport
FDF20_RS19160	COG1113	amino acid transport
FDF20_RS19180	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
FDF20_RS19185	COG1960	acyl-CoA dehydrogenase activity
FDF20_RS19190	COG1024	Enoyl-CoA hydratase
FDF20_RS19195	COG1024	Enoyl-CoA hydratase
FDF20_RS19200	COG0477	Major facilitator Superfamily
FDF20_RS19205	COG3916	Acyl-homoserine-lactone synthase
FDF20_RS19225	COG2267	carboxylic ester hydrolase activity
FDF20_RS19245	COG0271	Belongs to the BolA IbaG family
FDF20_RS19255	COG1192	Involved in chromosome partitioning
FDF20_RS19270	COG0586	Pfam SNARE associated Golgi protein
FDF20_RS19275	COG2259	Doxx family
FDF20_RS19280	COG4399	Belongs to the UPF0754 family
FDF20_RS19285	COG0518	GMP synthase (glutamine-hydrolyzing) activity
FDF20_RS19285	COG0519	Catalyzes the synthesis of GMP from XMP
FDF20_RS19330	COG0281	malic enzyme
FDF20_RS19335	COG2837	iron assimilation
FDF20_RS19340	COG1280	lysine exporter protein (LysE YggA)
FDF20_RS19345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
FDF20_RS19350	COG1121	(ABC) transporter
FDF20_RS19415	COG0386	Belongs to the glutathione peroxidase family
FDF20_RS19430	COG1309	transcriptional regulator
FDF20_RS19435	COG0697	spore germination
FDF20_RS19450	COG0758	DNA mediated transformation
FDF20_RS19485	COG1309	transcriptional regulator
FDF20_RS19520	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
FDF20_RS19530	COG0655	NAD(P)H dehydrogenase (quinone) activity
FDF20_RS19565	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDF20_RS19585	COG1253	flavin adenine dinucleotide binding
FDF20_RS19595	COG2860	membrane
FDF20_RS19600	COG0477	Major facilitator Superfamily
FDF20_RS19610	COG0318	PFAM AMP-dependent synthetase and ligase
FDF20_RS19625	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FDF20_RS19640	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
FDF20_RS19650	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FDF20_RS19655	COG0606	chelatase, subunit chli
FDF20_RS19695	COG0589	response to stress
FDF20_RS19700	COG0659	secondary active sulfate transmembrane transporter activity
FDF20_RS19715	COG1061	Type III restriction enzyme res subunit
FDF20_RS19740	COG0606	chelatase, subunit chli
FDF20_RS19750	COG0347	Belongs to the P(II) protein family
FDF20_RS19755	COG0004	ammonium transporteR
FDF20_RS19765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDF20_RS19765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
FDF20_RS19805	COG0795	lipopolysaccharide-transporting ATPase activity
FDF20_RS19810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
FDF20_RS19815	COG0793	Belongs to the peptidase S41A family
FDF20_RS19830	COG2197	response regulator
FDF20_RS19840	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
FDF20_RS19935	COG0739	heme binding
FDF20_RS19980	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FDF20_RS19990	COG1192	Involved in chromosome partitioning
FDF20_RS20040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
FDF20_RS20210	COG2207	Transcriptional regulator
FDF20_RS20215	COG0633	Ferredoxin
FDF20_RS20250	COG1309	transcriptional regulator
FDF20_RS20290	COG1373	ATPase (AAA superfamily
FDF20_RS20450	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FDF20_RS20495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
FDF20_RS20515	COG1192	Involved in chromosome partitioning
FDF20_RS20670	COG0482	sulfurtransferase activity
FDF20_RS20685	COG0488	(ABC) transporter
FDF20_RS20690	COG3173	Aminoglycoside phosphotransferase
FDF20_RS20725	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
FDF20_RS20760	COG0501	Belongs to the peptidase M48B family