locus-tag	class	description
HBN37_RS00010	COG0592	DNA-directed DNA polymerase activity
HBN37_RS00020	COG0187	DNA topoisomerase II activity
HBN37_RS00030	COG0586	Pfam SNARE associated Golgi protein
HBN37_RS00035	COG0488	(ABC) transporter
HBN37_RS00060	COG0596	Alpha beta hydrolase
HBN37_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HBN37_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBN37_RS00110	COG0733	neurotransmitter:sodium symporter activity
HBN37_RS00150	COG2233	PERMEase
HBN37_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN37_RS00200	COG2814	Major facilitator Superfamily
HBN37_RS00205	COG0656	L-ascorbic acid biosynthetic process
HBN37_RS00210	COG0583	DNA-binding transcription factor activity
HBN37_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBN37_RS00230	COG1064	alcohol dehydrogenase
HBN37_RS00235	COG2818	Glycosylase
HBN37_RS00250	COG1194	a g-specific adenine glycosylase
HBN37_RS00270	COG2983	Belongs to the UPF0260 family
HBN37_RS00275	COG2133	pyrroloquinoline quinone binding
HBN37_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HBN37_RS00285	COG2116	formate transmembrane transporter activity
HBN37_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBN37_RS00310	COG1335	isochorismatase
HBN37_RS00315	COG0385	Bile acid
HBN37_RS00320	COG0534	Mate efflux family protein
HBN37_RS00325	COG1683	Conserved Protein
HBN37_RS00345	COG0625	glutathione transferase activity
HBN37_RS00355	COG1113	amino acid transport
HBN37_RS00365	COG0523	cobalamin synthesis protein
HBN37_RS00375	COG2188	Transcriptional regulator
HBN37_RS00405	COG0010	Belongs to the arginase family
HBN37_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBN37_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HBN37_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HBN37_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HBN37_RS00540	COG0534	Mate efflux family protein
HBN37_RS00545	COG0436	Aminotransferase
HBN37_RS00550	COG2733	membrane
HBN37_RS00565	COG2918	glutathione biosynthetic process
HBN37_RS00575	COG3501	Rhs element vgr protein
HBN37_RS00580	COG0791	NLP P60 protein
HBN37_RS00580	COG1388	LysM domain
HBN37_RS00595	COG3150	esterase
HBN37_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS00610	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HBN37_RS00620	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN37_RS00630	COG2233	PERMEase
HBN37_RS00635	COG2351	hydroxyisourate hydrolase activity
HBN37_RS00670	COG3706	GGDEF domain
HBN37_RS00685	COG1393	Belongs to the ArsC family
HBN37_RS00690	COG0708	Exodeoxyribonuclease III
HBN37_RS00710	COG0189	ligase activity
HBN37_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HBN37_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBN37_RS00755	COG4942	peptidase
HBN37_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBN37_RS00775	COG2119	membrane
HBN37_RS00780	COG4774	siderophore transport
HBN37_RS00785	COG0426	domain, Protein
HBN37_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN37_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HBN37_RS00830	COG1902	pentaerythritol trinitrate reductase activity
HBN37_RS00835	COG1519	Transferase
HBN37_RS00840	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBN37_RS00845	COG0668	transmembrane transport
HBN37_RS00855	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBN37_RS00860	COG1335	isochorismatase
HBN37_RS00865	COG1522	sequence-specific DNA binding
HBN37_RS00870	COG3328	transposase activity
HBN37_RS00895	COG2205	protein histidine kinase activity
HBN37_RS00895	COG0784	Response regulator, receiver
HBN37_RS00895	COG2198	Histidine kinase
HBN37_RS00900	COG3162	membrane
HBN37_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBN37_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN37_RS00925	COG3706	GGDEF domain
HBN37_RS00935	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HBN37_RS00940	COG1309	transcriptional regulator
HBN37_RS00960	COG0351	phosphomethylpyrimidine kinase
HBN37_RS00960	COG0352	thiamine-phosphate diphosphorylase activity
HBN37_RS00960	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBN37_RS00970	COG2814	Major facilitator Superfamily
HBN37_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBN37_RS00995	COG1113	amino acid transport
HBN37_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBN37_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS01020	COG1335	isochorismatase
HBN37_RS01050	COG2814	Major facilitator Superfamily
HBN37_RS01055	COG0583	DNA-binding transcription factor activity
HBN37_RS01075	COG0667	Aldo Keto reductase
HBN37_RS01110	COG1733	regulation of RNA biosynthetic process
HBN37_RS01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBN37_RS01180	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBN37_RS01195	COG2329	Antibiotic biosynthesis monooxygenase
HBN37_RS01225	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HBN37_RS01255	COG0427	acetyl-CoA hydrolase
HBN37_RS01270	COG0745	RESPONSE REGULATOR receiver
HBN37_RS01280	COG0659	secondary active sulfate transmembrane transporter activity
HBN37_RS01285	COG4221	oxidoreductase activity
HBN37_RS01290	COG2873	o-acetylhomoserine
HBN37_RS01295	COG0488	(ABC) transporter
HBN37_RS01380	COG0833	amino acid
HBN37_RS01425	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBN37_RS01430	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HBN37_RS01445	COG2226	methyltransferase
HBN37_RS01495	COG0070	glutamate synthase
HBN37_RS01495	COG0067	glutamate synthase
HBN37_RS01495	COG0069	glutamate synthase activity
HBN37_RS01500	COG0493	'glutamate synthase
HBN37_RS01510	COG1704	LemA family
HBN37_RS01515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HBN37_RS01535	COG3307	-O-antigen
HBN37_RS01555	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBN37_RS01570	COG0194	GDP metabolic process
HBN37_RS01620	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBN37_RS01640	COG5380	lipid catabolic process
HBN37_RS01645	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBN37_RS01670	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBN37_RS01675	COG0277	FAD linked oxidase domain protein
HBN37_RS01685	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HBN37_RS01690	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBN37_RS01705	COG1289	transmembrane transporter activity
HBN37_RS01715	COG0628	permease
HBN37_RS01720	COG1192	Involved in chromosome partitioning
HBN37_RS01750	COG0833	amino acid
HBN37_RS01755	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBN37_RS01760	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBN37_RS01770	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS01810	COG0583	DNA-binding transcription factor activity
HBN37_RS01855	COG0517	IMP dehydrogenase activity
HBN37_RS01860	COG1983	PspC domain protein
HBN37_RS01870	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS01885	COG0408	coproporphyrinogen oxidase activity
HBN37_RS01905	COG0513	Belongs to the DEAD box helicase family
HBN37_RS01915	COG1127	ABC transporter
HBN37_RS01920	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HBN37_RS01930	COG2854	intermembrane phospholipid transfer
HBN37_RS01940	COG0598	Magnesium transport protein CorA
HBN37_RS01950	COG0494	nUDIX hydrolase
HBN37_RS01955	COG1040	competence protein
HBN37_RS01960	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBN37_RS01980	COG1946	Acyl-CoA thioesterase
HBN37_RS01985	COG1301	dicarboxylic acid transport
HBN37_RS02000	COG1959	2 iron, 2 sulfur cluster binding
HBN37_RS02005	COG1017	nitric oxide dioxygenase activity
HBN37_RS02005	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBN37_RS02010	COG0433	COG0433 Predicted ATPase
HBN37_RS02015	COG0626	cystathionine gamma-synthase activity
HBN37_RS02170	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS02175	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HBN37_RS02205	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HBN37_RS02210	COG0339	signal peptide processing
HBN37_RS02215	COG0557	exoribonuclease II activity
HBN37_RS02260	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBN37_RS02265	COG2169	Transcriptional regulator
HBN37_RS02270	COG0697	spore germination
HBN37_RS02275	COG1295	ribonuclease BN
HBN37_RS02310	COG1702	phosphate starvation-inducible protein PhoH
HBN37_RS02320	COG0741	lytic transglycosylase activity
HBN37_RS02320	COG1196	nuclear chromosome segregation
HBN37_RS02320	COG0739	heme binding
HBN37_RS02350	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HBN37_RS02355	COG1183	phosphatidylcholine synthase activity
HBN37_RS02400	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS02405	COG1309	transcriptional regulator
HBN37_RS02420	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBN37_RS02425	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS02445	COG2969	positive regulation of protein catabolic process
HBN37_RS02455	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HBN37_RS02470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HBN37_RS02475	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HBN37_RS02495	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBN37_RS02505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBN37_RS02510	COG1408	metallophosphoesterase
HBN37_RS02520	COG2199	diguanylate cyclase activity
HBN37_RS02580	COG1607	acyl-coa hydrolase
HBN37_RS02610	COG2350	Protein conserved in bacteria
HBN37_RS02620	COG0613	PHP domain protein
HBN37_RS02625	COG3781	membrane
HBN37_RS02635	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBN37_RS02640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBN37_RS02650	COG1862	Preprotein translocase
HBN37_RS02680	COG2205	protein histidine kinase activity
HBN37_RS02685	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HBN37_RS02705	COG0726	polysaccharide deacetylase
HBN37_RS02710	COG0463	Glycosyl transferase, family 2
HBN37_RS02715	COG0438	transferase activity, transferring glycosyl groups
HBN37_RS02780	COG0625	glutathione transferase activity
HBN37_RS02785	COG0583	DNA-binding transcription factor activity
HBN37_RS02790	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS02795	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS02805	COG2205	protein histidine kinase activity
HBN37_RS02810	COG0745	RESPONSE REGULATOR receiver
HBN37_RS02815	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HBN37_RS02835	COG2096	Adenosyltransferase
HBN37_RS02885	COG0285	dihydrofolate synthase activity
HBN37_RS02905	COG0450	alkyl hydroperoxide reductase
HBN37_RS02920	COG0477	Major facilitator Superfamily
HBN37_RS02925	COG1272	protein, Hemolysin III
HBN37_RS02960	COG0183	Belongs to the thiolase family
HBN37_RS02965	COG2207	Transcriptional regulator
HBN37_RS02985	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN37_RS03005	COG0183	Belongs to the thiolase family
HBN37_RS03015	COG2885	chlorophyll binding
HBN37_RS03015	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HBN37_RS03025	COG1690	Belongs to the RtcB family
HBN37_RS03030	COG0833	amino acid
HBN37_RS03040	COG2233	PERMEase
HBN37_RS03070	COG2094	Belongs to the DNA glycosylase MPG family
HBN37_RS03075	COG4772	TonB-dependent receptor
HBN37_RS03090	COG1902	pentaerythritol trinitrate reductase activity
HBN37_RS03095	COG0679	Auxin Efflux Carrier
HBN37_RS03105	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBN37_RS03110	COG0354	folic acid binding
HBN37_RS03120	COG3189	MarR family transcriptional regulator
HBN37_RS03125	COG2824	Alkylphosphonate utilization operon protein PhnA
HBN37_RS03130	COG3422	double-strand break repair
HBN37_RS03170	COG0840	transmembrane signaling receptor activity
HBN37_RS03190	COG5510	response to toxic substance
HBN37_RS03200	COG2832	Protein of unknown function (DUF454)
HBN37_RS03205	COG1376	ErfK ybiS ycfS ynhG family protein
HBN37_RS03245	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HBN37_RS03255	COG1289	transmembrane transporter activity
HBN37_RS03260	COG2814	Major facilitator Superfamily
HBN37_RS03280	COG1115	amino acid carrier protein
HBN37_RS03285	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBN37_RS03290	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBN37_RS03295	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HBN37_RS03335	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBN37_RS03345	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBN37_RS03350	COG1077	Cell shape determining protein MreB Mrl
HBN37_RS03355	COG1792	Involved in formation and maintenance of cell shape
HBN37_RS03360	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HBN37_RS03365	COG0424	maF-like protein
HBN37_RS03370	COG1530	ribonuclease E activity
HBN37_RS03380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBN37_RS03390	COG0560	Phosphoserine phosphatase
HBN37_RS03400	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBN37_RS03425	COG2207	Transcriptional regulator
HBN37_RS03445	COG1113	amino acid transport
HBN37_RS03450	COG2828	Protein conserved in bacteria
HBN37_RS03455	COG0142	geranyltranstransferase activity
HBN37_RS03460	COG2315	Protein conserved in bacteria
HBN37_RS03475	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBN37_RS03495	COG2194	sulfuric ester hydrolase activity
HBN37_RS03500	COG0745	RESPONSE REGULATOR receiver
HBN37_RS03505	COG0642	Histidine kinase
HBN37_RS03515	COG0004	ammonium transporteR
HBN37_RS03520	COG0583	DNA-binding transcription factor activity
HBN37_RS03540	COG0525	valine-tRNA ligase activity
HBN37_RS03550	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS03560	COG0393	Putative heavy-metal-binding
HBN37_RS03565	COG0393	Putative heavy-metal-binding
HBN37_RS03570	COG1538	Outer membrane efflux protein
HBN37_RS03580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN37_RS03585	COG0671	phosphoesterase, PA-phosphatase related
HBN37_RS03615	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HBN37_RS03630	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HBN37_RS03630	COG1648	precorrin-2 dehydrogenase activity
HBN37_RS03635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HBN37_RS03640	COG1733	regulation of RNA biosynthetic process
HBN37_RS03650	COG0531	amino acid
HBN37_RS03665	COG0321	lipoyl(octanoyl) transferase activity
HBN37_RS03670	COG2921	Belongs to the UPF0250 family
HBN37_RS03710	COG2009	succinate dehydrogenase
HBN37_RS03715	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HBN37_RS03720	COG1053	succinate dehydrogenase
HBN37_RS03725	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HBN37_RS03750	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBN37_RS03770	COG2354	Protein conserved in bacteria
HBN37_RS03775	COG2321	neutral zinc metallopeptidase
HBN37_RS03800	COG2843	Capsule synthesis protein
HBN37_RS03815	COG0589	response to stress
HBN37_RS03835	COG0505	Belongs to the CarA family
HBN37_RS03860	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBN37_RS03865	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBN37_RS03915	COG0477	Major facilitator Superfamily
HBN37_RS03920	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBN37_RS03935	COG1597	lipid kinase activity
HBN37_RS03940	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBN37_RS03970	COG0584	glycerophosphoryl diester phosphodiesterase
HBN37_RS03990	COG0741	lytic transglycosylase activity
HBN37_RS04010	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HBN37_RS04025	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBN37_RS04050	COG0778	Nitroreductase
HBN37_RS04065	COG1929	Belongs to the glycerate kinase type-1 family
HBN37_RS04070	COG0243	molybdopterin cofactor binding
HBN37_RS04075	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBN37_RS04080	COG3339	Conserved Protein
HBN37_RS04090	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HBN37_RS04105	COG1113	amino acid transport
HBN37_RS04115	COG0019	diaminopimelate decarboxylase activity
HBN37_RS04125	COG1280	lysine exporter protein (LysE YggA)
HBN37_RS04130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HBN37_RS04160	COG0463	Glycosyl transferase, family 2
HBN37_RS04180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN37_RS04215	COG4591	ABC-type transport system involved in lipoprotein release permease component
HBN37_RS04220	COG1136	(ABC) transporter
HBN37_RS04225	COG0658	competence protein
HBN37_RS04225	COG2333	competence protein COMEC
HBN37_RS04235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HBN37_RS04235	COG0616	signal peptide processing
HBN37_RS04240	COG0596	Alpha beta hydrolase
HBN37_RS04245	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBN37_RS04255	COG0628	permease
HBN37_RS04290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBN37_RS04310	COG0823	Involved in the tonB-independent uptake of proteins
HBN37_RS04330	COG0824	Thioesterase
HBN37_RS04335	COG1473	amidohydrolase
HBN37_RS04355	COG0047	phosphoribosylformylglycinamidine synthase activity
HBN37_RS04355	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBN37_RS04360	COG2814	Major facilitator Superfamily
HBN37_RS04370	COG1024	Enoyl-CoA hydratase
HBN37_RS04375	COG1056	cytidyltransferase-related domain
HBN37_RS04375	COG1051	belongs to the nudix hydrolase family
HBN37_RS04385	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBN37_RS04400	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HBN37_RS04415	COG4625	pathogenesis
HBN37_RS04420	COG0583	DNA-binding transcription factor activity
HBN37_RS04425	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HBN37_RS04430	COG4208	sulfate ABC transporter
HBN37_RS04435	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HBN37_RS04445	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HBN37_RS04450	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBN37_RS04455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBN37_RS04475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBN37_RS04490	COG0681	Belongs to the peptidase S26 family
HBN37_RS04505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBN37_RS04515	COG1381	Involved in DNA repair and RecF pathway recombination
HBN37_RS04520	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HBN37_RS04530	COG4221	oxidoreductase activity
HBN37_RS04565	COG0436	Aminotransferase
HBN37_RS04585	COG0556	nucleotide-excision repair
HBN37_RS04690	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBN37_RS04695	COG4197	protein conserved in bacteria, prophage-related
HBN37_RS04965	COG2070	2-Nitropropane dioxygenase
HBN37_RS04995	COG1215	transferase activity, transferring glycosyl groups
HBN37_RS05010	COG0415	Belongs to the DNA photolyase family
HBN37_RS05020	COG1252	NADH dehydrogenase
HBN37_RS05025	COG1686	Belongs to the peptidase S11 family
HBN37_RS05040	COG1187	pseudouridine synthase activity
HBN37_RS05235	COG5410	chromosome segregation
HBN37_RS05410	COG0582	viral genome integration into host DNA
HBN37_RS05435	COG0477	Major facilitator Superfamily
HBN37_RS05440	COG0583	DNA-binding transcription factor activity
HBN37_RS05455	COG0612	Peptidase, M16
HBN37_RS05480	COG0352	thiamine-phosphate diphosphorylase activity
HBN37_RS05515	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBN37_RS05530	COG1309	transcriptional regulator
HBN37_RS05540	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBN37_RS05545	COG0076	glutamate decarboxylase activity
HBN37_RS05555	COG1522	sequence-specific DNA binding
HBN37_RS05560	COG3961	Belongs to the TPP enzyme family
HBN37_RS05565	COG1113	amino acid transport
HBN37_RS05570	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBN37_RS05575	COG0573	inorganic phosphate transmembrane transporter activity
HBN37_RS05585	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HBN37_RS05590	COG0616	signal peptide processing
HBN37_RS05600	COG3328	transposase activity
HBN37_RS05630	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBN37_RS05635	COG1686	Belongs to the peptidase S11 family
HBN37_RS05660	COG0583	DNA-binding transcription factor activity
HBN37_RS05665	COG1067	ATP-dependent peptidase activity
HBN37_RS05710	COG1966	Carbon starvation protein
HBN37_RS05715	COG2879	small protein
HBN37_RS05750	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HBN37_RS05750	COG2508	Transcriptional regulator
HBN37_RS05770	COG1113	amino acid transport
HBN37_RS05775	COG0583	DNA-binding transcription factor activity
HBN37_RS05780	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN37_RS05785	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN37_RS05795	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS05800	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN37_RS05805	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HBN37_RS05805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBN37_RS05840	COG2814	Major facilitator Superfamily
HBN37_RS05845	COG4948	Mandelate Racemase Muconate Lactonizing
HBN37_RS05855	COG1309	transcriptional regulator
HBN37_RS05875	COG1741	Belongs to the pirin family
HBN37_RS05885	COG2964	Protein conserved in bacteria
HBN37_RS05900	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBN37_RS05905	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBN37_RS05910	COG4605	iron ion homeostasis
HBN37_RS05915	COG4604	ABC transporter, ATP-binding protein
HBN37_RS05920	COG4607	ABC-type enterochelin transport system periplasmic component
HBN37_RS05925	COG4774	siderophore transport
HBN37_RS05935	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBN37_RS05940	COG1021	2,3-dihydroxybenzoate-AMP ligase
HBN37_RS05945	COG3433	isochorismatase activity
HBN37_RS05945	COG1535	isochorismatase
HBN37_RS05960	COG1132	(ABC) transporter
HBN37_RS05970	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HBN37_RS05980	COG1169	isochorismate synthase
HBN37_RS05995	COG3739	integral membrane protein
HBN37_RS06030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HBN37_RS06060	COG0308	aminopeptidase N
HBN37_RS06065	COG0512	Glutamine amidotransferase of anthranilate synthase
HBN37_RS06075	COG3104	oligopeptide transport
HBN37_RS06080	COG0174	glutamine synthetase
HBN37_RS06090	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HBN37_RS06125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBN37_RS06130	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBN37_RS06135	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBN37_RS06155	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBN37_RS06160	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HBN37_RS06165	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HBN37_RS06180	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS06185	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBN37_RS06190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBN37_RS06200	COG2223	nitrite transmembrane transporter activity
HBN37_RS06210	COG0024	Methionine aminopeptidase
HBN37_RS06215	COG0052	Belongs to the universal ribosomal protein uS2 family
HBN37_RS06230	COG2207	Transcriptional regulator
HBN37_RS06255	COG2951	lytic endotransglycosylase activity
HBN37_RS06260	COG0772	Belongs to the SEDS family
HBN37_RS06275	COG0842	Transport permease protein
HBN37_RS06280	COG1131	(ABC) transporter
HBN37_RS06325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN37_RS06340	COG4215	(ABC) transporter
HBN37_RS06345	COG4160	amino acid transport
HBN37_RS06350	COG4598	ABC transporter
HBN37_RS06360	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBN37_RS06370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBN37_RS06385	COG1720	tRNA m6t6A37 methyltransferase activity
HBN37_RS06405	COG0745	RESPONSE REGULATOR receiver
HBN37_RS06410	COG0642	Histidine kinase
HBN37_RS06420	COG0494	nUDIX hydrolase
HBN37_RS06430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBN37_RS06435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBN37_RS06440	COG3139	Protein of unknown function (DUF1315)
HBN37_RS06445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBN37_RS06450	COG1301	dicarboxylic acid transport
HBN37_RS06455	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS06460	COG2819	hydrolase of the alpha beta superfamily
HBN37_RS06470	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HBN37_RS06480	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBN37_RS06485	COG1234	tRNA 3'-trailer cleavage
HBN37_RS06515	COG2363	Small membrane protein
HBN37_RS06535	COG0513	Belongs to the DEAD box helicase family
HBN37_RS06545	COG0778	Nitroreductase
HBN37_RS06575	COG1286	toxin biosynthetic process
HBN37_RS06600	COG4783	chaperone-mediated protein folding
HBN37_RS06605	COG1610	YqeY-like protein
HBN37_RS06705	COG3111	PFAM Bacterial OB fold (BOF) protein
HBN37_RS06730	COG3243	poly(R)-hydroxyalkanoic acid synthase
HBN37_RS06735	COG0786	glutamate:sodium symporter activity
HBN37_RS06745	COG2186	Transcriptional regulator
HBN37_RS06795	COG0477	Major facilitator Superfamily
HBN37_RS06820	COG2985	domain, Protein
HBN37_RS06830	COG2995	paraquat-inducible protein a
HBN37_RS06835	COG3008	intermembrane lipid transfer
HBN37_RS06835	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HBN37_RS06855	COG0482	sulfurtransferase activity
HBN37_RS06875	COG3173	Aminoglycoside phosphotransferase
HBN37_RS06885	COG2433	Pfam Transposase IS66
HBN37_RS06920	COG1301	dicarboxylic acid transport
HBN37_RS06930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBN37_RS06935	COG2011	ABC-type metal ion transport system permease component
HBN37_RS06940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBN37_RS06945	COG1464	Belongs to the NlpA lipoprotein family
HBN37_RS06950	COG0151	Belongs to the GarS family
HBN37_RS06955	COG0138	bifunctional purine biosynthesis protein purh
HBN37_RS06960	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HBN37_RS06990	COG2308	Evidence 4 Homologs of previously reported genes of
HBN37_RS07000	COG1305	Transglutaminase-like
HBN37_RS07010	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBN37_RS07015	COG0305	Participates in initiation and elongation during chromosome replication
HBN37_RS07040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HBN37_RS07050	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBN37_RS07055	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HBN37_RS07090	COG0726	polysaccharide deacetylase
HBN37_RS07090	COG1649	PFAM Uncharacterised BCR, COG1649
HBN37_RS07095	COG1215	transferase activity, transferring glycosyl groups
HBN37_RS07100	COG3658	cytochrome
HBN37_RS07110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBN37_RS07125	COG0583	DNA-binding transcription factor activity
HBN37_RS07145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBN37_RS07150	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBN37_RS07165	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS07170	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBN37_RS07175	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN37_RS07200	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HBN37_RS07205	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HBN37_RS07215	COG2205	protein histidine kinase activity
HBN37_RS07220	COG0745	RESPONSE REGULATOR receiver
HBN37_RS07225	COG0174	glutamine synthetase
HBN37_RS07245	COG0729	surface antigen
HBN37_RS07270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBN37_RS07275	COG2814	Major facilitator Superfamily
HBN37_RS07290	COG0583	DNA-binding transcription factor activity
HBN37_RS07305	COG1187	pseudouridine synthase activity
HBN37_RS07325	COG0802	atpase or kinase
HBN37_RS07330	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBN37_RS07340	COG1923	regulation of RNA biosynthetic process
HBN37_RS07345	COG0697	spore germination
HBN37_RS07360	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBN37_RS07370	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBN37_RS07375	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBN37_RS07375	COG0519	Catalyzes the synthesis of GMP from XMP
HBN37_RS07380	COG4302	ethanolamine ammonia-lyase activity
HBN37_RS07385	COG4303	Ethanolamine ammonia lyase large subunit
HBN37_RS07390	COG0531	amino acid
HBN37_RS07410	COG1454	alcohol dehydrogenase
HBN37_RS07415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBN37_RS07425	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HBN37_RS07445	COG0308	aminopeptidase N
HBN37_RS07475	COG1605	Chorismate mutase
HBN37_RS07490	COG1309	transcriptional regulator
HBN37_RS07500	COG0668	transmembrane transport
HBN37_RS07535	COG4773	Receptor
HBN37_RS07555	COG0488	(ABC) transporter
HBN37_RS07560	COG0589	response to stress
HBN37_RS07585	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HBN37_RS07595	COG3135	benzoate transporter
HBN37_RS07600	COG1522	sequence-specific DNA binding
HBN37_RS07610	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBN37_RS07615	COG0583	DNA-binding transcription factor activity
HBN37_RS07625	COG0183	Belongs to the thiolase family
HBN37_RS07635	COG2030	dehydratase
HBN37_RS07655	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBN37_RS07665	COG0824	Thioesterase
HBN37_RS07670	COG1454	alcohol dehydrogenase
HBN37_RS07680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBN37_RS07700	COG0069	glutamate synthase activity
HBN37_RS07780	COG3620	sequence-specific DNA binding
HBN37_RS07905	COG1598	PFAM Uncharacterised protein family UPF0150
HBN37_RS07935	COG0739	heme binding
HBN37_RS07935	COG0741	lytic transglycosylase activity
HBN37_RS07935	COG1196	nuclear chromosome segregation
HBN37_RS08000	COG2814	Major facilitator Superfamily
HBN37_RS08015	COG0511	ligase activity, forming carbon-carbon bonds
HBN37_RS08035	COG1116	anion transmembrane transporter activity
HBN37_RS08035	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBN37_RS08040	COG0745	RESPONSE REGULATOR receiver
HBN37_RS08050	COG2146	nitrite reductase [NAD(P)H] activity
HBN37_RS08050	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN37_RS08055	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN37_RS08060	COG0243	molybdopterin cofactor binding
HBN37_RS08070	COG0243	molybdopterin cofactor binding
HBN37_RS08075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBN37_RS08090	COG0315	cyclic pyranopterin monophosphate synthase activity
HBN37_RS08090	COG0521	Mo-molybdopterin cofactor biosynthetic process
HBN37_RS08095	COG0303	'Molybdopterin
HBN37_RS08105	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBN37_RS08110	COG0697	spore germination
HBN37_RS08130	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HBN37_RS08135	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBN37_RS08190	COG2204	response regulator
HBN37_RS08195	COG3852	Histidine kinase
HBN37_RS08215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBN37_RS08220	COG0575	Belongs to the CDS family
HBN37_RS08255	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBN37_RS08270	COG2137	regulation of response to DNA damage stimulus
HBN37_RS08280	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HBN37_RS08285	COG1011	Hydrolase
HBN37_RS08310	COG1522	sequence-specific DNA binding
HBN37_RS08320	COG1113	amino acid transport
HBN37_RS08335	COG0659	secondary active sulfate transmembrane transporter activity
HBN37_RS08340	COG2135	peptidase activity
HBN37_RS08355	COG5001	Diguanylate cyclase
HBN37_RS08355	COG3300	MHYT domain
HBN37_RS08375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBN37_RS08375	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HBN37_RS08375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBN37_RS08380	COG1105	Belongs to the carbohydrate kinase PfkB family
HBN37_RS08385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBN37_RS08385	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBN37_RS08415	COG0024	Methionine aminopeptidase
HBN37_RS08420	COG0583	DNA-binding transcription factor activity
HBN37_RS08430	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HBN37_RS08435	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBN37_RS08440	COG0517	IMP dehydrogenase activity
HBN37_RS08440	COG0516	GMP reductase activity
HBN37_RS08465	COG0552	protein localization to endoplasmic reticulum
HBN37_RS08475	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HBN37_RS08490	COG4890	Cyd operon protein YbgT
HBN37_RS08495	COG1294	oxidase, subunit
HBN37_RS08510	COG1585	Membrane protein implicated in regulation of membrane protease activity
HBN37_RS08520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBN37_RS08525	COG4774	siderophore transport
HBN37_RS08540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBN37_RS08545	COG0569	domain protein
HBN37_RS08550	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBN37_RS08580	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HBN37_RS08585	COG0542	response to heat
HBN37_RS08610	COG1902	pentaerythritol trinitrate reductase activity
HBN37_RS08610	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN37_RS08655	COG2323	membrane
HBN37_RS08660	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HBN37_RS08670	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBN37_RS08675	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBN37_RS08680	COG0183	Belongs to the thiolase family
HBN37_RS08685	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBN37_RS08690	COG0596	Alpha beta hydrolase
HBN37_RS08695	COG2271	Major facilitator Superfamily
HBN37_RS08700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBN37_RS08705	COG3485	protocatechuate 3,4-dioxygenase
HBN37_RS08710	COG3485	protocatechuate 3,4-dioxygenase
HBN37_RS08715	COG0710	3-dehydroquinate dehydratase activity
HBN37_RS08720	COG3420	alginic acid biosynthetic process
HBN37_RS08725	COG3659	wide pore channel activity
HBN37_RS08730	COG4993	Dehydrogenase
HBN37_RS08740	COG2391	methyltransferase activity
HBN37_RS08755	COG1414	Transcriptional regulator
HBN37_RS08760	COG0583	DNA-binding transcription factor activity
HBN37_RS08765	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS08800	COG2814	Major facilitator Superfamily
HBN37_RS08810	COG0154	amidase activity
HBN37_RS08830	COG4638	Rieske (2fe-2S)
HBN37_RS08840	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS08850	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN37_RS08860	COG3733	amine oxidase
HBN37_RS08870	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS08880	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBN37_RS08885	COG0183	Belongs to the thiolase family
HBN37_RS08890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBN37_RS08895	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBN37_RS08905	COG4829	muconolactone delta-isomerase
HBN37_RS08910	COG4948	Mandelate Racemase Muconate Lactonizing
HBN37_RS08915	COG0583	DNA-binding transcription factor activity
HBN37_RS08925	COG2186	Transcriptional regulator
HBN37_RS08945	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS08965	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS08970	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS08975	COG3829	transcription factor binding
HBN37_RS08985	COG3162	membrane
HBN37_RS09000	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS09015	COG0753	catalase activity
HBN37_RS09035	COG1846	Transcriptional regulator
HBN37_RS09040	COG1902	pentaerythritol trinitrate reductase activity
HBN37_RS09040	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN37_RS09050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBN37_RS09080	COG1309	transcriptional regulator
HBN37_RS09090	COG1335	isochorismatase
HBN37_RS09095	COG0583	DNA-binding transcription factor activity
HBN37_RS09105	COG0475	glutathione-regulated potassium exporter activity
HBN37_RS09105	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBN37_RS09115	COG1473	amidohydrolase
HBN37_RS09125	COG2831	hemolysin activation secretion protein
HBN37_RS09130	COG3210	domain, Protein
HBN37_RS09160	COG2188	Transcriptional regulator
HBN37_RS09175	COG0583	DNA-binding transcription factor activity
HBN37_RS09205	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBN37_RS09225	COG1566	PFAM secretion protein HlyD family protein
HBN37_RS09240	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS09245	COG0129	dihydroxy-acid dehydratase activity
HBN37_RS09255	COG0583	DNA-binding transcription factor activity
HBN37_RS09260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBN37_RS09270	COG2084	Dehydrogenase
HBN37_RS09275	COG2207	Transcriptional regulator
HBN37_RS09290	COG1064	alcohol dehydrogenase
HBN37_RS09305	COG1120	ATPase activity
HBN37_RS09325	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBN37_RS09440	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HBN37_RS09495	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS09510	COG2207	Transcriptional regulator
HBN37_RS09520	COG2205	protein histidine kinase activity
HBN37_RS09525	COG0745	RESPONSE REGULATOR receiver
HBN37_RS09530	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN37_RS09535	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBN37_RS09540	COG1538	Outer membrane efflux protein
HBN37_RS09550	COG2072	flavoprotein involved in K transport
HBN37_RS09570	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBN37_RS09590	COG3539	Fimbrial protein
HBN37_RS09620	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HBN37_RS09630	COG0753	catalase activity
HBN37_RS09645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBN37_RS09710	COG1535	isochorismatase
HBN37_RS09710	COG3433	isochorismatase activity
HBN37_RS09715	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS09720	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HBN37_RS09725	COG4149	molybdate abc transporter
HBN37_RS09730	COG0725	ABC transporter, periplasmic molybdate-binding protein
HBN37_RS09740	COG4638	Rieske (2fe-2S)
HBN37_RS09745	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBN37_RS09750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBN37_RS09750	COG0543	2 iron, 2 sulfur cluster binding
HBN37_RS09775	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS09790	COG2207	Transcriptional regulator
HBN37_RS09800	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS09805	COG2610	gluconate transmembrane transporter activity
HBN37_RS09815	COG0583	DNA-binding transcription factor activity
HBN37_RS09825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBN37_RS09830	COG2031	fatty acid transporter
HBN37_RS09835	COG0183	Belongs to the thiolase family
HBN37_RS09840	COG0583	DNA-binding transcription factor activity
HBN37_RS09845	COG0583	DNA-binding transcription factor activity
HBN37_RS09860	COG1027	Aspartate ammonia-lyase
HBN37_RS09870	COG0477	Major facilitator Superfamily
HBN37_RS09890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBN37_RS09895	COG4521	taurine ABC transporter
HBN37_RS09910	COG2188	Transcriptional regulator
HBN37_RS09920	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBN37_RS09925	COG1733	regulation of RNA biosynthetic process
HBN37_RS09930	COG3708	Transcriptional regulator
HBN37_RS09930	COG2207	Transcriptional regulator
HBN37_RS09945	COG0730	response to heat
HBN37_RS09955	COG3453	Protein conserved in bacteria
HBN37_RS09955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBN37_RS09965	COG3781	membrane
HBN37_RS09970	COG1063	alcohol dehydrogenase
HBN37_RS09980	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBN37_RS09985	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBN37_RS09990	COG0022	dehydrogenase e1 component
HBN37_RS09995	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBN37_RS10000	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBN37_RS10015	COG3706	GGDEF domain
HBN37_RS10030	COG0133	tryptophan synthase activity
HBN37_RS10040	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBN37_RS10075	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HBN37_RS10100	COG2226	methyltransferase
HBN37_RS10155	COG0842	Transport permease protein
HBN37_RS10160	COG0842	Transport permease protein
HBN37_RS10165	COG1131	(ABC) transporter
HBN37_RS10180	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBN37_RS10185	COG4773	Receptor
HBN37_RS10205	COG0730	response to heat
HBN37_RS10210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HBN37_RS10230	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HBN37_RS10285	COG4264	IucA IucC family
HBN37_RS10290	COG4264	IucA IucC family
HBN37_RS10310	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBN37_RS10325	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS10330	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS10335	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBN37_RS10345	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBN37_RS10350	COG0776	regulation of translation
HBN37_RS10375	COG0822	iron-sulfur transferase activity
HBN37_RS10380	COG0316	Belongs to the HesB IscA family
HBN37_RS10410	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBN37_RS10430	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBN37_RS10435	COG0702	epimerase
HBN37_RS10470	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBN37_RS10480	COG0339	signal peptide processing
HBN37_RS10530	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HBN37_RS10535	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HBN37_RS10565	COG0776	regulation of translation
HBN37_RS10630	COG0084	hydrolase, TatD family'
HBN37_RS10650	COG1663	tetraacyldisaccharide 4'-kinase activity
HBN37_RS10655	COG1132	(ABC) transporter
HBN37_RS10665	COG0811	peptide transport
HBN37_RS10670	COG1475	DNA binding
HBN37_RS10675	COG1192	Involved in chromosome partitioning
HBN37_RS10685	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBN37_RS10700	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBN37_RS10705	COG0191	fructose-bisphosphate aldolase activity
HBN37_RS10725	COG0424	maF-like protein
HBN37_RS10730	COG2850	peptidyl-arginine hydroxylation
HBN37_RS10740	COG0640	Transcriptional regulator
HBN37_RS10755	COG3619	membrane
HBN37_RS10760	COG3122	Protein conserved in bacteria
HBN37_RS10765	COG1132	(ABC) transporter
HBN37_RS10785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HBN37_RS10790	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBN37_RS10800	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBN37_RS10800	COG0506	proline dehydrogenase activity
HBN37_RS10800	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBN37_RS10805	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBN37_RS10820	COG3698	Phosphodiester glycosidase
HBN37_RS10830	COG2353	YceI-like domain
HBN37_RS10840	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBN37_RS10885	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HBN37_RS10885	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBN37_RS10910	COG3539	Fimbrial protein
HBN37_RS10915	COG3121	Chaperone
HBN37_RS10940	COG0697	spore germination
HBN37_RS10950	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBN37_RS10960	COG0583	DNA-binding transcription factor activity
HBN37_RS10980	COG1309	transcriptional regulator
HBN37_RS10995	COG1522	sequence-specific DNA binding
HBN37_RS11005	COG1126	abc transporter atp-binding protein
HBN37_RS11010	COG0765	amino acid transport
HBN37_RS11015	COG0765	amino acid transport
HBN37_RS11045	COG1464	Belongs to the NlpA lipoprotein family
HBN37_RS11055	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBN37_RS11060	COG2011	ABC-type metal ion transport system permease component
HBN37_RS11065	COG0012	GTP binding
HBN37_RS11090	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBN37_RS11130	COG0386	Belongs to the glutathione peroxidase family
HBN37_RS11140	COG0436	Aminotransferase
HBN37_RS11180	COG3634	alkyl hydroperoxide reductase activity
HBN37_RS11195	COG0583	DNA-binding transcription factor activity
HBN37_RS11200	COG0798	PFAM Bile acid sodium symporter
HBN37_RS11205	COG0640	Transcriptional regulator
HBN37_RS11220	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HBN37_RS11230	COG0583	DNA-binding transcription factor activity
HBN37_RS11240	COG1953	Uracil, thiamine, allantoin
HBN37_RS11250	COG2175	clavaminate synthase activity
HBN37_RS11255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBN37_RS11260	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HBN37_RS11265	COG4521	taurine ABC transporter
HBN37_RS11275	COG0477	Major facilitator Superfamily
HBN37_RS11300	COG1271	oxidase subunit
HBN37_RS11305	COG1294	oxidase, subunit
HBN37_RS11315	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBN37_RS11335	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HBN37_RS11355	COG3052	prosthetic group binding
HBN37_RS11360	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HBN37_RS11370	COG2814	Major facilitator Superfamily
HBN37_RS11390	COG1346	cytolysis
HBN37_RS11400	COG0583	DNA-binding transcription factor activity
HBN37_RS11405	COG0625	glutathione transferase activity
HBN37_RS11410	COG0625	glutathione transferase activity
HBN37_RS11415	COG0583	DNA-binding transcription factor activity
HBN37_RS11430	COG1045	serine acetyltransferase
HBN37_RS11435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBN37_RS11440	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBN37_RS11450	COG1280	lysine exporter protein (LysE YggA)
HBN37_RS11465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBN37_RS11470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBN37_RS11475	COG1126	abc transporter atp-binding protein
HBN37_RS11480	COG0765	amino acid transport
HBN37_RS11485	COG0765	amino acid transport
HBN37_RS11505	COG0784	Response regulator, receiver
HBN37_RS11505	COG2205	protein histidine kinase activity
HBN37_RS11525	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBN37_RS11545	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS11595	COG0583	DNA-binding transcription factor activity
HBN37_RS11615	COG0318	PFAM AMP-dependent synthetase and ligase
HBN37_RS11620	COG1309	transcriptional regulator
HBN37_RS11625	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS11630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBN37_RS11635	COG1024	Enoyl-CoA hydratase
HBN37_RS11640	COG4770	biotin carboxylase activity
HBN37_RS11650	COG0583	DNA-binding transcription factor activity
HBN37_RS11665	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS11675	COG2814	Major facilitator Superfamily
HBN37_RS11685	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBN37_RS11690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBN37_RS11695	COG2814	Major facilitator Superfamily
HBN37_RS11700	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS11705	COG1024	Enoyl-CoA hydratase
HBN37_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS11715	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBN37_RS11720	COG0183	Belongs to the thiolase family
HBN37_RS11730	COG2814	Major facilitator Superfamily
HBN37_RS11740	COG1024	Enoyl-CoA hydratase
HBN37_RS11755	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS11760	COG2814	Major facilitator Superfamily
HBN37_RS11765	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBN37_RS11770	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HBN37_RS11785	COG3842	ATPase activity
HBN37_RS11790	COG1840	ABC-type Fe3 transport system, periplasmic component
HBN37_RS11800	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN37_RS11805	COG1414	Transcriptional regulator
HBN37_RS11815	COG0583	DNA-binding transcription factor activity
HBN37_RS11820	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBN37_RS11825	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS11835	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBN37_RS11845	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS11850	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBN37_RS11855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN37_RS11860	COG2267	carboxylic ester hydrolase activity
HBN37_RS11880	COG3038	cytochrome b561
HBN37_RS11885	COG0753	catalase activity
HBN37_RS11920	COG2050	protein possibly involved in aromatic compounds catabolism
HBN37_RS11930	COG3327	negative regulation of DNA-templated transcription, initiation
HBN37_RS11935	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HBN37_RS11940	COG0183	Belongs to the thiolase family
HBN37_RS11945	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBN37_RS11950	COG1024	Enoyl-CoA hydratase
HBN37_RS11955	COG1024	Enoyl-CoA hydratase
HBN37_RS11960	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBN37_RS11965	COG2151	metal-sulfur cluster biosynthetic enzyme
HBN37_RS11970	COG3396	Phenylacetate-CoA oxygenase
HBN37_RS11975	COG3460	Phenylacetate-CoA oxygenase
HBN37_RS11980	COG3396	Phenylacetate-CoA oxygenase
HBN37_RS11985	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS11985	COG2030	dehydratase
HBN37_RS11990	COG1760	l-serine dehydratase
HBN37_RS11995	COG0531	amino acid
HBN37_RS12000	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS12015	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN37_RS12025	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBN37_RS12045	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBN37_RS12055	COG0789	Transcriptional regulator
HBN37_RS12070	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBN37_RS12085	COG2807	transmembrane transport
HBN37_RS12090	COG0590	tRNA wobble adenosine to inosine editing
HBN37_RS12205	COG1116	anion transmembrane transporter activity
HBN37_RS12210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBN37_RS12220	COG0864	Transcriptional regulator
HBN37_RS12240	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBN37_RS12245	COG0439	Biotin carboxylase
HBN37_RS12260	COG1063	alcohol dehydrogenase
HBN37_RS12270	COG1309	transcriptional regulator
HBN37_RS12290	COG0038	chloride channel
HBN37_RS12295	COG4770	biotin carboxylase activity
HBN37_RS12315	COG1914	H( )-stimulated, divalent metal cation uptake system
HBN37_RS12320	COG0583	DNA-binding transcription factor activity
HBN37_RS12335	COG3209	COG3209 Rhs family protein
HBN37_RS12340	COG3501	Rhs element vgr protein
HBN37_RS12370	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBN37_RS12390	COG2814	Major facilitator Superfamily
HBN37_RS12400	COG1560	Kdo2-lipid A biosynthetic process
HBN37_RS12410	COG5006	permease, DMT superfamily
HBN37_RS12415	COG1522	sequence-specific DNA binding
HBN37_RS12430	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HBN37_RS12440	COG4122	O-methyltransferase activity
HBN37_RS12470	COG1538	Outer membrane efflux protein
HBN37_RS12480	COG1137	ATPase activity
HBN37_RS12485	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HBN37_RS12495	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HBN37_RS12500	COG0517	IMP dehydrogenase activity
HBN37_RS12500	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HBN37_RS12540	COG2814	Major facilitator Superfamily
HBN37_RS12575	COG1278	Cold shock
HBN37_RS12580	COG1280	lysine exporter protein (LysE YggA)
HBN37_RS12615	COG1570	exodeoxyribonuclease VII activity
HBN37_RS12665	COG0583	DNA-binding transcription factor activity
HBN37_RS12670	COG4638	Rieske (2fe-2S)
HBN37_RS12675	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBN37_RS12680	COG0543	2 iron, 2 sulfur cluster binding
HBN37_RS12680	COG0633	Ferredoxin
HBN37_RS12685	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS12690	COG3135	benzoate transporter
HBN37_RS12695	COG2814	Major facilitator Superfamily
HBN37_RS12710	COG1643	Atp-dependent helicase
HBN37_RS12715	COG0450	alkyl hydroperoxide reductase
HBN37_RS12735	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HBN37_RS12740	COG0625	glutathione transferase activity
HBN37_RS12750	COG2885	chlorophyll binding
HBN37_RS12785	COG0542	response to heat
HBN37_RS12800	COG1765	OsmC-like protein
HBN37_RS12815	COG0667	Aldo Keto reductase
HBN37_RS12830	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBN37_RS12840	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBN37_RS12850	COG0527	aspartate kinase activity
HBN37_RS12860	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBN37_RS12870	COG3038	cytochrome b561
HBN37_RS12875	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HBN37_RS12880	COG2252	PERMEase
HBN37_RS12890	COG2072	flavoprotein involved in K transport
HBN37_RS12905	COG1741	Belongs to the pirin family
HBN37_RS12910	COG1309	transcriptional regulator
HBN37_RS12935	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
HBN37_RS12975	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN37_RS12975	COG1902	pentaerythritol trinitrate reductase activity
HBN37_RS12985	COG5001	Diguanylate cyclase
HBN37_RS12985	COG2203	Gaf domain
HBN37_RS12985	COG3706	GGDEF domain
HBN37_RS12985	COG4251	negative regulation of phosphorylation
HBN37_RS12995	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBN37_RS13015	COG4172	Belongs to the ABC transporter superfamily
HBN37_RS13020	COG4239	(ABC) transporter, permease
HBN37_RS13025	COG4174	ABC transporter (Permease)
HBN37_RS13035	COG1388	LysM domain
HBN37_RS13035	COG0741	lytic transglycosylase activity
HBN37_RS13035	COG0741	lytic transglycosylase activity
HBN37_RS13035	COG1388	LysM domain
HBN37_RS13040	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBN37_RS13080	COG0583	DNA-binding transcription factor activity
HBN37_RS13085	COG1279	arginine transmembrane transporter activity
HBN37_RS13105	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN37_RS13110	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN37_RS13115	COG0006	proline dipeptidase activity
HBN37_RS13200	COG0739	heme binding
HBN37_RS13200	COG1196	nuclear chromosome segregation
HBN37_RS13200	COG0741	lytic transglycosylase activity
HBN37_RS13260	COG4695	Portal protein
HBN37_RS13360	COG0305	Participates in initiation and elongation during chromosome replication
HBN37_RS13430	COG2194	sulfuric ester hydrolase activity
HBN37_RS13475	COG0739	heme binding
HBN37_RS13665	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBN37_RS13690	COG3384	dioxygenase
HBN37_RS13700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBN37_RS13705	COG2878	Part of a membrane complex involved in electron transport
HBN37_RS13710	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBN37_RS13735	COG0768	penicillin binding
HBN37_RS13740	COG0742	ribosomal rna small subunit methyltransferase
HBN37_RS13755	COG0830	nickel cation binding
HBN37_RS13765	COG0804	urea catabolic process
HBN37_RS13805	COG1253	flavin adenine dinucleotide binding
HBN37_RS13810	COG2851	Citrate transporter
HBN37_RS13865	COG1773	rubredoxin
HBN37_RS13870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN37_RS13880	COG0583	DNA-binding transcription factor activity
HBN37_RS13905	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HBN37_RS13910	COG4181	ATPase activity
HBN37_RS13955	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HBN37_RS13975	COG0306	phosphate transporter
HBN37_RS13985	COG3958	Transketolase
HBN37_RS13990	COG3959	Transketolase, thiamine diphosphate binding domain
HBN37_RS13995	COG2271	Major facilitator Superfamily
HBN37_RS14000	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS14005	COG0583	DNA-binding transcription factor activity
HBN37_RS14020	COG2223	nitrite transmembrane transporter activity
HBN37_RS14025	COG2207	Transcriptional regulator
HBN37_RS14030	COG2066	Belongs to the glutaminase family
HBN37_RS14035	COG0242	peptide deformylase activity
HBN37_RS14040	COG0477	Major facilitator Superfamily
HBN37_RS14050	COG0028	Belongs to the TPP enzyme family
HBN37_RS14065	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS14070	COG2267	carboxylic ester hydrolase activity
HBN37_RS14080	COG2271	Major facilitator Superfamily
HBN37_RS14085	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN37_RS14095	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS14115	COG1414	Transcriptional regulator
HBN37_RS14130	COG1024	Enoyl-CoA hydratase
HBN37_RS14140	COG1215	transferase activity, transferring glycosyl groups
HBN37_RS14145	COG0726	polysaccharide deacetylase
HBN37_RS14145	COG1649	PFAM Uncharacterised BCR, COG1649
HBN37_RS14155	COG4681	YaeQ
HBN37_RS14165	COG0523	cobalamin synthesis protein
HBN37_RS14170	COG3328	transposase activity
HBN37_RS14180	COG1607	acyl-coa hydrolase
HBN37_RS14190	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN37_RS14195	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN37_RS14200	COG1309	transcriptional regulator
HBN37_RS14225	COG2040	homocysteine
HBN37_RS14230	COG0531	amino acid
HBN37_RS14285	COG1595	DNA-templated transcription, initiation
HBN37_RS14295	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBN37_RS14300	COG0477	Major facilitator Superfamily
HBN37_RS14320	COG0084	hydrolase, TatD family'
HBN37_RS14355	COG0629	single-stranded DNA binding
HBN37_RS14410	COG0582	viral genome integration into host DNA
HBN37_RS14505	COG0592	DNA-directed DNA polymerase activity
HBN37_RS14545	COG2026	Addiction module toxin, RelE StbE family
HBN37_RS14785	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBN37_RS14855	COG0405	Gamma-glutamyltransferase
HBN37_RS14860	COG2814	Major facilitator Superfamily
HBN37_RS14870	COG2050	protein possibly involved in aromatic compounds catabolism
HBN37_RS14885	COG1090	epimerase
HBN37_RS14905	COG0420	3'-5' exonuclease activity
HBN37_RS14930	COG0735	belongs to the Fur family
HBN37_RS14935	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HBN37_RS14955	COG0121	glutamine amidotransferase
HBN37_RS14970	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBN37_RS14980	COG0210	DNA helicase
HBN37_RS14985	COG2885	chlorophyll binding
HBN37_RS14990	COG0204	Acyl-transferase
HBN37_RS15005	COG2894	cell division
HBN37_RS15030	COG1280	lysine exporter protein (LysE YggA)
HBN37_RS15035	COG1674	ftsk spoiiie
HBN37_RS15035	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HBN37_RS15040	COG0492	ferredoxin-NADP+ reductase activity
HBN37_RS15045	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HBN37_RS15055	COG0456	acetyltransferase
HBN37_RS15115	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HBN37_RS15115	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBN37_RS15135	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS15155	COG0473	3-isopropylmalate dehydrogenase activity
HBN37_RS15160	COG0583	DNA-binding transcription factor activity
HBN37_RS15180	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBN37_RS15205	COG0564	pseudouridine synthase activity
HBN37_RS15215	COG0358	DNA primase activity
HBN37_RS15230	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HBN37_RS15260	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBN37_RS15290	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBN37_RS15300	COG0352	thiamine-phosphate diphosphorylase activity
HBN37_RS15300	COG0351	phosphomethylpyrimidine kinase
HBN37_RS15300	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBN37_RS15305	COG1652	LysM domain
HBN37_RS15330	COG1399	metal-binding, possibly nucleic acid-binding protein
HBN37_RS15335	COG3101	peptidyl-lysine hydroxylation
HBN37_RS15340	COG0009	L-threonylcarbamoyladenylate synthase
HBN37_RS15345	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBN37_RS15350	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBN37_RS15365	COG4106	trans-aconitate 2-methyltransferase activity
HBN37_RS15380	COG0596	Alpha beta hydrolase
HBN37_RS15380	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBN37_RS15380	COG2226	methyltransferase
HBN37_RS15385	COG1877	trehalose-phosphatase activity
HBN37_RS15390	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HBN37_RS15395	COG2223	nitrite transmembrane transporter activity
HBN37_RS15415	COG1196	nuclear chromosome segregation
HBN37_RS15425	COG0730	response to heat
HBN37_RS15440	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBN37_RS15450	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBN37_RS15500	COG0489	protein tyrosine kinase activity
HBN37_RS15510	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBN37_RS15510	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBN37_RS15540	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HBN37_RS15545	COG2081	HI0933 family
HBN37_RS15555	COG0668	transmembrane transport
HBN37_RS15575	COG0583	DNA-binding transcription factor activity
HBN37_RS15595	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBN37_RS15600	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBN37_RS15630	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HBN37_RS15665	COG2205	protein histidine kinase activity
HBN37_RS15670	COG0745	RESPONSE REGULATOR receiver
HBN37_RS15690	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBN37_RS15720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN37_RS15735	COG0583	DNA-binding transcription factor activity
HBN37_RS15755	COG1473	amidohydrolase
HBN37_RS15765	COG0583	DNA-binding transcription factor activity
HBN37_RS15780	COG0583	DNA-binding transcription factor activity
HBN37_RS15785	COG1053	succinate dehydrogenase
HBN37_RS15795	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HBN37_RS15800	COG2814	Major facilitator Superfamily
HBN37_RS15805	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS15810	COG0583	DNA-binding transcription factor activity
HBN37_RS15815	COG1063	alcohol dehydrogenase
HBN37_RS15845	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HBN37_RS15850	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HBN37_RS15855	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBN37_RS15870	COG3667	copper resistance
HBN37_RS15875	COG2132	Multicopper oxidase
HBN37_RS15885	COG0561	phosphatase activity
HBN37_RS15890	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBN37_RS15915	COG1214	PFAM Peptidase M22, glycoprotease
HBN37_RS15970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBN37_RS15980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HBN37_RS15985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HBN37_RS15990	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBN37_RS16050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBN37_RS16060	COG1846	Transcriptional regulator
HBN37_RS16065	COG1764	response to oxidative stress
HBN37_RS16115	COG0037	tRNA processing
HBN37_RS16125	COG0248	Ppx GppA phosphatase
HBN37_RS16155	COG0072	phenylalanine-tRNA ligase activity
HBN37_RS16195	COG1238	metal cluster binding
HBN37_RS16200	COG0625	glutathione transferase activity
HBN37_RS16215	COG0318	PFAM AMP-dependent synthetase and ligase
HBN37_RS16220	COG3028	Belongs to the UPF0307 family
HBN37_RS16225	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBN37_RS16245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBN37_RS16250	COG0617	tRNA 3'-terminal CCA addition
HBN37_RS16255	COG1555	photosystem II stabilization
HBN37_RS16260	COG3956	TIGRFAM MazG family protein
HBN37_RS16270	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBN37_RS16290	COG5002	protein histidine kinase activity
HBN37_RS16290	COG2205	protein histidine kinase activity
HBN37_RS16290	COG0784	Response regulator, receiver
HBN37_RS16295	COG1024	Enoyl-CoA hydratase
HBN37_RS16300	COG2084	Dehydrogenase
HBN37_RS16305	COG3622	Belongs to the hyi family
HBN37_RS16335	COG0697	spore germination
HBN37_RS16345	COG2814	Major facilitator Superfamily
HBN37_RS16350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBN37_RS16360	COG0583	DNA-binding transcription factor activity
HBN37_RS16370	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HBN37_RS16385	COG0084	hydrolase, TatD family'
HBN37_RS16400	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HBN37_RS16430	COG0440	acetolactate synthase activity
HBN37_RS16435	COG0028	Belongs to the TPP enzyme family
HBN37_RS16460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN37_RS16465	COG1136	(ABC) transporter
HBN37_RS16465	COG0577	efflux transmembrane transporter activity
HBN37_RS16470	COG1538	Outer membrane efflux protein
HBN37_RS16485	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HBN37_RS16490	COG1162	GTPase activity
HBN37_RS16500	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HBN37_RS16520	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBN37_RS16525	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS16565	COG2986	histidine ammonia-lyase
HBN37_RS16580	COG0318	PFAM AMP-dependent synthetase and ligase
HBN37_RS16590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBN37_RS16635	COG1426	Protein conserved in bacteria
HBN37_RS16670	COG0793	Belongs to the peptidase S41A family
HBN37_RS16685	COG2267	carboxylic ester hydrolase activity
HBN37_RS16695	COG1012	belongs to the aldehyde dehydrogenase family
HBN37_RS16700	COG3265	gluconokinase activity
HBN37_RS16710	COG0800	Aldolase
HBN37_RS16725	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBN37_RS16730	COG0280	phosphate acetyltransferase
HBN37_RS16730	COG0857	belongs to the CobB CobQ family
HBN37_RS16735	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HBN37_RS16735	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HBN37_RS16760	COG0740	serine-type endopeptidase activity
HBN37_RS16770	COG4774	siderophore transport
HBN37_RS16780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBN37_RS16790	COG2813	Specifically methylates the guanine in position
HBN37_RS16790	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBN37_RS16895	COG0788	formyltetrahydrofolate deformylase activity
HBN37_RS16920	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBN37_RS16920	COG4651	solute:proton antiporter activity
HBN37_RS16940	COG0724	RNA recognition motif
HBN37_RS16945	COG0210	DNA helicase
HBN37_RS16970	COG1733	regulation of RNA biosynthetic process
HBN37_RS16980	COG2900	Belongs to the SlyX family
HBN37_RS16990	COG1280	lysine exporter protein (LysE YggA)
HBN37_RS16995	COG1560	Kdo2-lipid A biosynthetic process
HBN37_RS17005	COG1301	dicarboxylic acid transport
HBN37_RS17060	COG0473	3-isopropylmalate dehydrogenase activity
HBN37_RS17125	COG0583	DNA-binding transcription factor activity
HBN37_RS17135	COG0625	glutathione transferase activity
HBN37_RS17140	COG2378	regulation of single-species biofilm formation
HBN37_RS17145	COG0546	phosphoglycolate phosphatase activity
HBN37_RS17160	COG1530	ribonuclease E activity
HBN37_RS17165	COG0318	PFAM AMP-dependent synthetase and ligase
HBN37_RS17180	COG0583	DNA-binding transcription factor activity
HBN37_RS17185	COG4221	oxidoreductase activity
HBN37_RS17190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBN37_RS17200	COG0534	Mate efflux family protein
HBN37_RS17215	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HBN37_RS17255	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HBN37_RS17260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBN37_RS17275	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBN37_RS17285	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HBN37_RS17285	COG0644	oxidoreductase
HBN37_RS17290	COG0425	Belongs to the sulfur carrier protein TusA family
HBN37_RS17295	COG4535	Mg2 and Co2 transporter CorC
HBN37_RS17305	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBN37_RS17325	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBN37_RS17330	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBN37_RS17330	COG0475	glutathione-regulated potassium exporter activity
HBN37_RS17335	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBN37_RS17345	COG0484	heat shock protein binding
HBN37_RS17350	COG0789	Transcriptional regulator
HBN37_RS17355	COG0598	Magnesium transport protein CorA
HBN37_RS17375	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBN37_RS17380	COG1074	ATP-dependent DNA helicase activity
HBN37_RS17385	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HBN37_RS17405	COG2226	methyltransferase
HBN37_RS17420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN37_RS17425	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HBN37_RS17440	COG2111	Na H antiporter
HBN37_RS17440	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBN37_RS17445	COG1006	Multisubunit Na H antiporter MnhC subunit
HBN37_RS17450	COG0651	ATP synthesis coupled electron transport
HBN37_RS17460	COG2212	antiporter activity
HBN37_RS17480	COG0195	Participates in both transcription termination and antitermination
HBN37_RS17530	COG0237	dephospho-CoA kinase activity
HBN37_RS17540	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBN37_RS17555	COG0497	DNA recombination
HBN37_RS17565	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBN37_RS17595	COG2169	Transcriptional regulator
HBN37_RS17595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBN37_RS17600	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBN37_RS17665	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBN37_RS17680	COG0326	Molecular chaperone. Has ATPase activity
HBN37_RS17695	COG2056	Na+-H+ antiporter family
HBN37_RS17700	COG0596	Alpha beta hydrolase
HBN37_RS17795	COG0546	phosphoglycolate phosphatase activity
HBN37_RS17800	COG1716	ATPase activity
HBN37_RS17845	COG0181	hydroxymethylbilane synthase activity
HBN37_RS17855	COG3275	phosphorelay sensor kinase activity
HBN37_RS17875	COG1538	Outer membrane efflux protein
HBN37_RS17880	COG0697	spore germination
HBN37_RS17905	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBN37_RS17910	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBN37_RS17915	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBN37_RS17920	COG0772	Belongs to the SEDS family
HBN37_RS17945	COG4974	Belongs to the 'phage' integrase family
HBN37_RS17950	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBN37_RS17960	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HBN37_RS17970	COG2197	response regulator
HBN37_RS17985	COG0793	Belongs to the peptidase S41A family
HBN37_RS17990	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBN37_RS17995	COG0795	lipopolysaccharide-transporting ATPase activity
HBN37_RS18035	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBN37_RS18035	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBN37_RS18045	COG0004	ammonium transporteR
HBN37_RS18050	COG0347	Belongs to the P(II) protein family
HBN37_RS18060	COG0606	chelatase, subunit chli
HBN37_RS18135	COG1061	Type III restriction enzyme res subunit
HBN37_RS18150	COG0659	secondary active sulfate transmembrane transporter activity
HBN37_RS18155	COG0589	response to stress
HBN37_RS18190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBN37_RS18240	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HBN37_RS18285	COG1061	Type III restriction enzyme res subunit
HBN37_RS18300	COG0659	secondary active sulfate transmembrane transporter activity
HBN37_RS18305	COG0589	response to stress
HBN37_RS18335	COG0606	chelatase, subunit chli
HBN37_RS18350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBN37_RS18365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HBN37_RS18380	COG0318	PFAM AMP-dependent synthetase and ligase
HBN37_RS18390	COG0477	Major facilitator Superfamily
HBN37_RS18395	COG2860	membrane
HBN37_RS18405	COG1253	flavin adenine dinucleotide binding
HBN37_RS18425	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBN37_RS18460	COG0655	NAD(P)H dehydrogenase (quinone) activity
HBN37_RS18470	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBN37_RS18505	COG1309	transcriptional regulator
HBN37_RS18540	COG0758	DNA mediated transformation
HBN37_RS18550	COG0697	spore germination
HBN37_RS18555	COG1309	transcriptional regulator
HBN37_RS18570	COG0386	Belongs to the glutathione peroxidase family
HBN37_RS18635	COG1121	(ABC) transporter
HBN37_RS18640	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBN37_RS18645	COG1280	lysine exporter protein (LysE YggA)
HBN37_RS18650	COG2837	iron assimilation
HBN37_RS18660	COG0281	malic enzyme
HBN37_RS18705	COG0519	Catalyzes the synthesis of GMP from XMP
HBN37_RS18705	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBN37_RS18710	COG4399	Belongs to the UPF0754 family
HBN37_RS18715	COG2259	Doxx family
HBN37_RS18720	COG0586	Pfam SNARE associated Golgi protein
HBN37_RS18735	COG1192	Involved in chromosome partitioning
HBN37_RS18745	COG0271	Belongs to the BolA IbaG family
HBN37_RS18765	COG2267	carboxylic ester hydrolase activity
HBN37_RS18785	COG3321	synthase
HBN37_RS18785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HBN37_RS18785	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HBN37_RS18785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBN37_RS18790	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS18800	COG2197	response regulator
HBN37_RS18810	COG3916	Acyl-homoserine-lactone synthase
HBN37_RS18815	COG0477	Major facilitator Superfamily
HBN37_RS18820	COG1024	Enoyl-CoA hydratase
HBN37_RS18825	COG1024	Enoyl-CoA hydratase
HBN37_RS18830	COG1960	acyl-CoA dehydrogenase activity
HBN37_RS18835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBN37_RS18855	COG1113	amino acid transport
HBN37_RS18860	COG1113	amino acid transport
HBN37_RS18865	COG0251	oxidation-reduction process
HBN37_RS18905	COG0564	pseudouridine synthase activity
HBN37_RS18965	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBN37_RS18980	COG1802	Transcriptional regulator
HBN37_RS18990	COG1448	Aminotransferase
HBN37_RS18995	COG0277	FAD linked oxidase domain protein
HBN37_RS19005	COG2186	Transcriptional regulator
HBN37_RS19015	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBN37_RS19020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBN37_RS19035	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBN37_RS19040	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
HBN37_RS19095	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HBN37_RS19125	COG0728	peptidoglycan biosynthetic process
HBN37_RS19130	COG3023	N-Acetylmuramoyl-L-alanine amidase
HBN37_RS19185	COG0546	phosphoglycolate phosphatase activity
HBN37_RS19190	COG1028	Short-chain dehydrogenase reductase Sdr
HBN37_RS19210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBN37_RS19215	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBN37_RS19220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBN37_RS19225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBN37_RS19230	COG1116	anion transmembrane transporter activity
HBN37_RS19235	COG1309	transcriptional regulator
HBN37_RS19240	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBN37_RS19250	COG0196	riboflavin kinase activity
HBN37_RS19255	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBN37_RS19265	COG1047	Peptidyl-prolyl cis-trans
HBN37_RS19305	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBN37_RS19360	COG2951	lytic endotransglycosylase activity
HBN37_RS19365	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBN37_RS19380	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HBN37_RS19390	COG0671	phosphoesterase, PA-phosphatase related
HBN37_RS19395	COG0861	Integral membrane protein TerC family
HBN37_RS19405	COG0754	glutathionylspermidine amidase activity
HBN37_RS19415	COG0402	S-adenosylhomocysteine deaminase activity
HBN37_RS19430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBN37_RS19435	COG1230	cation diffusion facilitator family transporter
HBN37_RS19450	COG0706	membrane insertase activity