locus-tag	class	description
HBN41_RS00010	COG0592	DNA-directed DNA polymerase activity
HBN41_RS00020	COG0187	DNA topoisomerase II activity
HBN41_RS00030	COG0586	Pfam SNARE associated Golgi protein
HBN41_RS00035	COG0488	(ABC) transporter
HBN41_RS00060	COG0596	Alpha beta hydrolase
HBN41_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
HBN41_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
HBN41_RS00110	COG0733	neurotransmitter:sodium symporter activity
HBN41_RS00150	COG2233	PERMEase
HBN41_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN41_RS00200	COG2814	Major facilitator Superfamily
HBN41_RS00205	COG0656	L-ascorbic acid biosynthetic process
HBN41_RS00210	COG0583	DNA-binding transcription factor activity
HBN41_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBN41_RS00230	COG1064	alcohol dehydrogenase
HBN41_RS00235	COG2818	Glycosylase
HBN41_RS00250	COG1194	a g-specific adenine glycosylase
HBN41_RS00270	COG2983	Belongs to the UPF0260 family
HBN41_RS00275	COG2133	pyrroloquinoline quinone binding
HBN41_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
HBN41_RS00285	COG2116	formate transmembrane transporter activity
HBN41_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBN41_RS00310	COG1335	isochorismatase
HBN41_RS00315	COG0385	Bile acid
HBN41_RS00320	COG0534	Mate efflux family protein
HBN41_RS00325	COG1683	Conserved Protein
HBN41_RS00345	COG0625	glutathione transferase activity
HBN41_RS00355	COG1113	amino acid transport
HBN41_RS00365	COG0523	cobalamin synthesis protein
HBN41_RS00375	COG2188	Transcriptional regulator
HBN41_RS00405	COG0010	Belongs to the arginase family
HBN41_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBN41_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HBN41_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
HBN41_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
HBN41_RS00545	COG0534	Mate efflux family protein
HBN41_RS00550	COG0436	Aminotransferase
HBN41_RS00555	COG2733	membrane
HBN41_RS00570	COG2918	glutathione biosynthetic process
HBN41_RS00580	COG3501	Rhs element vgr protein
HBN41_RS00585	COG0791	NLP P60 protein
HBN41_RS00585	COG1388	LysM domain
HBN41_RS00600	COG3150	esterase
HBN41_RS00610	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS00615	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
HBN41_RS00625	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN41_RS00635	COG2233	PERMEase
HBN41_RS00640	COG2351	hydroxyisourate hydrolase activity
HBN41_RS00675	COG3706	GGDEF domain
HBN41_RS00690	COG1393	Belongs to the ArsC family
HBN41_RS00695	COG0708	Exodeoxyribonuclease III
HBN41_RS00715	COG0189	ligase activity
HBN41_RS00735	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
HBN41_RS00745	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HBN41_RS00760	COG4942	peptidase
HBN41_RS00770	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBN41_RS00780	COG2119	membrane
HBN41_RS00785	COG4774	siderophore transport
HBN41_RS00790	COG0426	domain, Protein
HBN41_RS00790	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN41_RS00815	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
HBN41_RS00835	COG1902	pentaerythritol trinitrate reductase activity
HBN41_RS00840	COG1519	Transferase
HBN41_RS00845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBN41_RS00850	COG0668	transmembrane transport
HBN41_RS00860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBN41_RS00865	COG1335	isochorismatase
HBN41_RS00870	COG1522	sequence-specific DNA binding
HBN41_RS00875	COG3328	transposase activity
HBN41_RS00900	COG0784	Response regulator, receiver
HBN41_RS00900	COG2205	protein histidine kinase activity
HBN41_RS00900	COG2198	Histidine kinase
HBN41_RS00905	COG3162	membrane
HBN41_RS00910	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBN41_RS00920	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN41_RS00930	COG3706	GGDEF domain
HBN41_RS00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HBN41_RS00945	COG1309	transcriptional regulator
HBN41_RS00965	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBN41_RS00965	COG0351	phosphomethylpyrimidine kinase
HBN41_RS00965	COG0352	thiamine-phosphate diphosphorylase activity
HBN41_RS00975	COG2814	Major facilitator Superfamily
HBN41_RS00990	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBN41_RS01000	COG1113	amino acid transport
HBN41_RS01010	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBN41_RS01015	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS01025	COG1335	isochorismatase
HBN41_RS01040	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
HBN41_RS01060	COG2814	Major facilitator Superfamily
HBN41_RS01065	COG0583	DNA-binding transcription factor activity
HBN41_RS01085	COG0667	Aldo Keto reductase
HBN41_RS01115	COG1733	regulation of RNA biosynthetic process
HBN41_RS01120	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBN41_RS01185	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
HBN41_RS01200	COG2329	Antibiotic biosynthesis monooxygenase
HBN41_RS01230	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
HBN41_RS01260	COG0427	acetyl-CoA hydrolase
HBN41_RS01275	COG0745	RESPONSE REGULATOR receiver
HBN41_RS01285	COG0659	secondary active sulfate transmembrane transporter activity
HBN41_RS01290	COG4221	oxidoreductase activity
HBN41_RS01295	COG2873	o-acetylhomoserine
HBN41_RS01300	COG0488	(ABC) transporter
HBN41_RS01385	COG0833	amino acid
HBN41_RS01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
HBN41_RS01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HBN41_RS01450	COG2226	methyltransferase
HBN41_RS01500	COG0070	glutamate synthase
HBN41_RS01500	COG0069	glutamate synthase activity
HBN41_RS01500	COG0067	glutamate synthase
HBN41_RS01505	COG0493	'glutamate synthase
HBN41_RS01515	COG1704	LemA family
HBN41_RS01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
HBN41_RS01540	COG3307	-O-antigen
HBN41_RS01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBN41_RS01575	COG0194	GDP metabolic process
HBN41_RS01625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
HBN41_RS01645	COG5380	lipid catabolic process
HBN41_RS01650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
HBN41_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HBN41_RS01680	COG0277	FAD linked oxidase domain protein
HBN41_RS01690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
HBN41_RS01695	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBN41_RS01710	COG1289	transmembrane transporter activity
HBN41_RS01720	COG0628	permease
HBN41_RS01725	COG1192	Involved in chromosome partitioning
HBN41_RS01755	COG0833	amino acid
HBN41_RS01760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBN41_RS01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBN41_RS01775	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS01815	COG0583	DNA-binding transcription factor activity
HBN41_RS01860	COG0517	IMP dehydrogenase activity
HBN41_RS01865	COG1983	PspC domain protein
HBN41_RS01875	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS01890	COG0408	coproporphyrinogen oxidase activity
HBN41_RS01910	COG0513	Belongs to the DEAD box helicase family
HBN41_RS01920	COG1127	ABC transporter
HBN41_RS01925	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
HBN41_RS01935	COG2854	intermembrane phospholipid transfer
HBN41_RS01945	COG0598	Magnesium transport protein CorA
HBN41_RS01955	COG0494	nUDIX hydrolase
HBN41_RS01960	COG1040	competence protein
HBN41_RS01965	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
HBN41_RS01985	COG1946	Acyl-CoA thioesterase
HBN41_RS01990	COG1301	dicarboxylic acid transport
HBN41_RS02005	COG1959	2 iron, 2 sulfur cluster binding
HBN41_RS02010	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBN41_RS02010	COG1017	nitric oxide dioxygenase activity
HBN41_RS02015	COG0433	COG0433 Predicted ATPase
HBN41_RS02020	COG0626	cystathionine gamma-synthase activity
HBN41_RS02175	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS02180	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
HBN41_RS02210	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
HBN41_RS02215	COG0339	signal peptide processing
HBN41_RS02220	COG0557	exoribonuclease II activity
HBN41_RS02265	COG0179	Fumarylacetoacetate (FAA) hydrolase
HBN41_RS02270	COG2169	Transcriptional regulator
HBN41_RS02275	COG0697	spore germination
HBN41_RS02280	COG1295	ribonuclease BN
HBN41_RS02320	COG1702	phosphate starvation-inducible protein PhoH
HBN41_RS02330	COG0739	heme binding
HBN41_RS02330	COG0741	lytic transglycosylase activity
HBN41_RS02330	COG1196	nuclear chromosome segregation
HBN41_RS02360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
HBN41_RS02365	COG1183	phosphatidylcholine synthase activity
HBN41_RS02410	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS02415	COG1309	transcriptional regulator
HBN41_RS02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBN41_RS02435	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS02455	COG2969	positive regulation of protein catabolic process
HBN41_RS02465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
HBN41_RS02480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
HBN41_RS02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
HBN41_RS02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HBN41_RS02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBN41_RS02520	COG1408	metallophosphoesterase
HBN41_RS02530	COG2199	diguanylate cyclase activity
HBN41_RS02590	COG1607	acyl-coa hydrolase
HBN41_RS02620	COG2350	Protein conserved in bacteria
HBN41_RS02630	COG0613	PHP domain protein
HBN41_RS02635	COG3781	membrane
HBN41_RS02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HBN41_RS02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
HBN41_RS02660	COG1862	Preprotein translocase
HBN41_RS02690	COG2205	protein histidine kinase activity
HBN41_RS02695	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
HBN41_RS02715	COG0726	polysaccharide deacetylase
HBN41_RS02720	COG0463	Glycosyl transferase, family 2
HBN41_RS02725	COG0438	transferase activity, transferring glycosyl groups
HBN41_RS02790	COG0625	glutathione transferase activity
HBN41_RS02795	COG0583	DNA-binding transcription factor activity
HBN41_RS02800	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS02805	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS02815	COG2205	protein histidine kinase activity
HBN41_RS02820	COG0745	RESPONSE REGULATOR receiver
HBN41_RS02825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
HBN41_RS02845	COG2096	Adenosyltransferase
HBN41_RS02895	COG0285	dihydrofolate synthase activity
HBN41_RS02915	COG0450	alkyl hydroperoxide reductase
HBN41_RS02930	COG0477	Major facilitator Superfamily
HBN41_RS02935	COG1272	protein, Hemolysin III
HBN41_RS02970	COG0183	Belongs to the thiolase family
HBN41_RS02975	COG2207	Transcriptional regulator
HBN41_RS02995	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN41_RS03015	COG0183	Belongs to the thiolase family
HBN41_RS03025	COG2885	chlorophyll binding
HBN41_RS03025	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
HBN41_RS03035	COG1690	Belongs to the RtcB family
HBN41_RS03040	COG0833	amino acid
HBN41_RS03050	COG2233	PERMEase
HBN41_RS03080	COG2094	Belongs to the DNA glycosylase MPG family
HBN41_RS03085	COG4772	TonB-dependent receptor
HBN41_RS03100	COG1902	pentaerythritol trinitrate reductase activity
HBN41_RS03105	COG0679	Auxin Efflux Carrier
HBN41_RS03115	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBN41_RS03120	COG0354	folic acid binding
HBN41_RS03130	COG3189	MarR family transcriptional regulator
HBN41_RS03135	COG2824	Alkylphosphonate utilization operon protein PhnA
HBN41_RS03140	COG3422	double-strand break repair
HBN41_RS03180	COG0840	transmembrane signaling receptor activity
HBN41_RS03200	COG5510	response to toxic substance
HBN41_RS03210	COG2832	Protein of unknown function (DUF454)
HBN41_RS03215	COG1376	ErfK ybiS ycfS ynhG family protein
HBN41_RS03255	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
HBN41_RS03265	COG1289	transmembrane transporter activity
HBN41_RS03270	COG2814	Major facilitator Superfamily
HBN41_RS03290	COG1115	amino acid carrier protein
HBN41_RS03295	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBN41_RS03300	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBN41_RS03305	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
HBN41_RS03345	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBN41_RS03355	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
HBN41_RS03360	COG1077	Cell shape determining protein MreB Mrl
HBN41_RS03365	COG1792	Involved in formation and maintenance of cell shape
HBN41_RS03370	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
HBN41_RS03375	COG0424	maF-like protein
HBN41_RS03380	COG1530	ribonuclease E activity
HBN41_RS03390	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBN41_RS03400	COG0560	Phosphoserine phosphatase
HBN41_RS03410	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBN41_RS03435	COG2207	Transcriptional regulator
HBN41_RS03455	COG1113	amino acid transport
HBN41_RS03460	COG2828	Protein conserved in bacteria
HBN41_RS03465	COG0142	geranyltranstransferase activity
HBN41_RS03470	COG2315	Protein conserved in bacteria
HBN41_RS03485	COG1752	Esterase of the alpha-beta hydrolase superfamily
HBN41_RS03505	COG2194	sulfuric ester hydrolase activity
HBN41_RS03510	COG0745	RESPONSE REGULATOR receiver
HBN41_RS03515	COG0642	Histidine kinase
HBN41_RS03525	COG0004	ammonium transporteR
HBN41_RS03530	COG0583	DNA-binding transcription factor activity
HBN41_RS03550	COG0525	valine-tRNA ligase activity
HBN41_RS03560	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS03570	COG0393	Putative heavy-metal-binding
HBN41_RS03575	COG0393	Putative heavy-metal-binding
HBN41_RS03580	COG1538	Outer membrane efflux protein
HBN41_RS03590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN41_RS03595	COG0671	phosphoesterase, PA-phosphatase related
HBN41_RS03625	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
HBN41_RS03640	COG1648	precorrin-2 dehydrogenase activity
HBN41_RS03640	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
HBN41_RS03645	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HBN41_RS03650	COG1733	regulation of RNA biosynthetic process
HBN41_RS03660	COG0531	amino acid
HBN41_RS03675	COG0321	lipoyl(octanoyl) transferase activity
HBN41_RS03680	COG2921	Belongs to the UPF0250 family
HBN41_RS03720	COG2009	succinate dehydrogenase
HBN41_RS03725	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
HBN41_RS03730	COG1053	succinate dehydrogenase
HBN41_RS03735	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
HBN41_RS03760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBN41_RS03780	COG2354	Protein conserved in bacteria
HBN41_RS03785	COG2321	neutral zinc metallopeptidase
HBN41_RS03820	COG2843	Capsule synthesis protein
HBN41_RS03835	COG0589	response to stress
HBN41_RS03855	COG0505	Belongs to the CarA family
HBN41_RS03880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBN41_RS03885	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HBN41_RS03935	COG0477	Major facilitator Superfamily
HBN41_RS03940	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
HBN41_RS03955	COG1597	lipid kinase activity
HBN41_RS03960	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBN41_RS03990	COG0584	glycerophosphoryl diester phosphodiesterase
HBN41_RS04010	COG0741	lytic transglycosylase activity
HBN41_RS04030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HBN41_RS04045	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBN41_RS04070	COG0778	Nitroreductase
HBN41_RS04085	COG1929	Belongs to the glycerate kinase type-1 family
HBN41_RS04090	COG0243	molybdopterin cofactor binding
HBN41_RS04095	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
HBN41_RS04100	COG3339	Conserved Protein
HBN41_RS04110	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
HBN41_RS04125	COG1113	amino acid transport
HBN41_RS04135	COG0019	diaminopimelate decarboxylase activity
HBN41_RS04145	COG1280	lysine exporter protein (LysE YggA)
HBN41_RS04150	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HBN41_RS04180	COG0463	Glycosyl transferase, family 2
HBN41_RS04200	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN41_RS04235	COG4591	ABC-type transport system involved in lipoprotein release permease component
HBN41_RS04240	COG1136	(ABC) transporter
HBN41_RS04245	COG2333	competence protein COMEC
HBN41_RS04245	COG0658	competence protein
HBN41_RS04255	COG0616	signal peptide processing
HBN41_RS04255	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HBN41_RS04260	COG0596	Alpha beta hydrolase
HBN41_RS04265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
HBN41_RS04275	COG0628	permease
HBN41_RS04310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBN41_RS04330	COG0823	Involved in the tonB-independent uptake of proteins
HBN41_RS04350	COG0824	Thioesterase
HBN41_RS04355	COG1473	amidohydrolase
HBN41_RS04375	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HBN41_RS04375	COG0047	phosphoribosylformylglycinamidine synthase activity
HBN41_RS04380	COG2814	Major facilitator Superfamily
HBN41_RS04390	COG1024	Enoyl-CoA hydratase
HBN41_RS04395	COG1056	cytidyltransferase-related domain
HBN41_RS04395	COG1051	belongs to the nudix hydrolase family
HBN41_RS04405	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HBN41_RS04420	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HBN41_RS04435	COG4625	pathogenesis
HBN41_RS04440	COG0583	DNA-binding transcription factor activity
HBN41_RS04445	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
HBN41_RS04450	COG4208	sulfate ABC transporter
HBN41_RS04455	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
HBN41_RS04465	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
HBN41_RS04470	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HBN41_RS04475	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
HBN41_RS04495	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBN41_RS04510	COG0681	Belongs to the peptidase S26 family
HBN41_RS04525	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
HBN41_RS04535	COG1381	Involved in DNA repair and RecF pathway recombination
HBN41_RS04540	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
HBN41_RS04550	COG4221	oxidoreductase activity
HBN41_RS04580	COG0436	Aminotransferase
HBN41_RS04600	COG0556	nucleotide-excision repair
HBN41_RS04655	COG2070	2-Nitropropane dioxygenase
HBN41_RS04685	COG1215	transferase activity, transferring glycosyl groups
HBN41_RS04700	COG0415	Belongs to the DNA photolyase family
HBN41_RS04710	COG1252	NADH dehydrogenase
HBN41_RS04715	COG1686	Belongs to the peptidase S11 family
HBN41_RS04730	COG1187	pseudouridine synthase activity
HBN41_RS04755	COG0477	Major facilitator Superfamily
HBN41_RS04760	COG0583	DNA-binding transcription factor activity
HBN41_RS04775	COG0612	Peptidase, M16
HBN41_RS04800	COG0352	thiamine-phosphate diphosphorylase activity
HBN41_RS04835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBN41_RS04850	COG1309	transcriptional regulator
HBN41_RS04860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
HBN41_RS04865	COG0076	glutamate decarboxylase activity
HBN41_RS04875	COG1522	sequence-specific DNA binding
HBN41_RS04880	COG3961	Belongs to the TPP enzyme family
HBN41_RS04885	COG1113	amino acid transport
HBN41_RS04890	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
HBN41_RS04895	COG0573	inorganic phosphate transmembrane transporter activity
HBN41_RS04905	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
HBN41_RS04910	COG0616	signal peptide processing
HBN41_RS04920	COG3328	transposase activity
HBN41_RS04950	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
HBN41_RS04955	COG1686	Belongs to the peptidase S11 family
HBN41_RS04980	COG0583	DNA-binding transcription factor activity
HBN41_RS04985	COG1067	ATP-dependent peptidase activity
HBN41_RS05030	COG1966	Carbon starvation protein
HBN41_RS05035	COG2879	small protein
HBN41_RS05070	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
HBN41_RS05070	COG2508	Transcriptional regulator
HBN41_RS05090	COG1113	amino acid transport
HBN41_RS05095	COG0583	DNA-binding transcription factor activity
HBN41_RS05100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN41_RS05105	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN41_RS05115	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS05120	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN41_RS05125	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
HBN41_RS05125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBN41_RS05160	COG2814	Major facilitator Superfamily
HBN41_RS05165	COG4948	Mandelate Racemase Muconate Lactonizing
HBN41_RS05175	COG1309	transcriptional regulator
HBN41_RS05195	COG1741	Belongs to the pirin family
HBN41_RS05205	COG2964	Protein conserved in bacteria
HBN41_RS05220	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBN41_RS05225	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
HBN41_RS05230	COG4605	iron ion homeostasis
HBN41_RS05235	COG4604	ABC transporter, ATP-binding protein
HBN41_RS05240	COG4607	ABC-type enterochelin transport system periplasmic component
HBN41_RS05245	COG4774	siderophore transport
HBN41_RS05255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HBN41_RS05260	COG1021	2,3-dihydroxybenzoate-AMP ligase
HBN41_RS05265	COG3433	isochorismatase activity
HBN41_RS05265	COG1535	isochorismatase
HBN41_RS05280	COG1132	(ABC) transporter
HBN41_RS05290	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
HBN41_RS05305	COG1169	isochorismate synthase
HBN41_RS05320	COG3739	integral membrane protein
HBN41_RS05355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
HBN41_RS05385	COG0308	aminopeptidase N
HBN41_RS05390	COG0512	Glutamine amidotransferase of anthranilate synthase
HBN41_RS05400	COG3104	oligopeptide transport
HBN41_RS05405	COG0174	glutamine synthetase
HBN41_RS05415	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
HBN41_RS05450	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
HBN41_RS05455	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HBN41_RS05460	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
HBN41_RS05480	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HBN41_RS05485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HBN41_RS05490	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HBN41_RS05505	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS05510	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBN41_RS05515	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBN41_RS05525	COG2223	nitrite transmembrane transporter activity
HBN41_RS05535	COG0024	Methionine aminopeptidase
HBN41_RS05540	COG0052	Belongs to the universal ribosomal protein uS2 family
HBN41_RS05555	COG2207	Transcriptional regulator
HBN41_RS05580	COG2951	lytic endotransglycosylase activity
HBN41_RS05585	COG0772	Belongs to the SEDS family
HBN41_RS05600	COG0842	Transport permease protein
HBN41_RS05605	COG1131	(ABC) transporter
HBN41_RS05650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN41_RS05665	COG4215	(ABC) transporter
HBN41_RS05670	COG4160	amino acid transport
HBN41_RS05675	COG4598	ABC transporter
HBN41_RS05685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBN41_RS05695	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBN41_RS05710	COG1720	tRNA m6t6A37 methyltransferase activity
HBN41_RS05730	COG0745	RESPONSE REGULATOR receiver
HBN41_RS05735	COG0642	Histidine kinase
HBN41_RS05745	COG0494	nUDIX hydrolase
HBN41_RS05755	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HBN41_RS05760	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
HBN41_RS05765	COG3139	Protein of unknown function (DUF1315)
HBN41_RS05770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HBN41_RS05775	COG1301	dicarboxylic acid transport
HBN41_RS05780	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS05785	COG2819	hydrolase of the alpha beta superfamily
HBN41_RS05795	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
HBN41_RS05805	COG2195	Cleaves the N-terminal amino acid of tripeptides
HBN41_RS05810	COG1234	tRNA 3'-trailer cleavage
HBN41_RS05840	COG2363	Small membrane protein
HBN41_RS05860	COG0513	Belongs to the DEAD box helicase family
HBN41_RS05870	COG0778	Nitroreductase
HBN41_RS05900	COG1286	toxin biosynthetic process
HBN41_RS05925	COG4783	chaperone-mediated protein folding
HBN41_RS05930	COG1610	YqeY-like protein
HBN41_RS06030	COG3111	PFAM Bacterial OB fold (BOF) protein
HBN41_RS06055	COG3243	poly(R)-hydroxyalkanoic acid synthase
HBN41_RS06060	COG0786	glutamate:sodium symporter activity
HBN41_RS06070	COG2186	Transcriptional regulator
HBN41_RS06120	COG0477	Major facilitator Superfamily
HBN41_RS06145	COG2985	domain, Protein
HBN41_RS06155	COG2995	paraquat-inducible protein a
HBN41_RS06160	COG3008	intermembrane lipid transfer
HBN41_RS06160	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
HBN41_RS06180	COG0482	sulfurtransferase activity
HBN41_RS06200	COG3173	Aminoglycoside phosphotransferase
HBN41_RS06210	COG2433	Pfam Transposase IS66
HBN41_RS06250	COG1301	dicarboxylic acid transport
HBN41_RS06260	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBN41_RS06265	COG2011	ABC-type metal ion transport system permease component
HBN41_RS06270	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBN41_RS06275	COG1464	Belongs to the NlpA lipoprotein family
HBN41_RS06280	COG0151	Belongs to the GarS family
HBN41_RS06285	COG0138	bifunctional purine biosynthesis protein purh
HBN41_RS06290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
HBN41_RS06320	COG2308	Evidence 4 Homologs of previously reported genes of
HBN41_RS06330	COG1305	Transglutaminase-like
HBN41_RS06340	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HBN41_RS06345	COG0305	Participates in initiation and elongation during chromosome replication
HBN41_RS06370	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
HBN41_RS06380	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
HBN41_RS06385	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
HBN41_RS06410	COG0726	polysaccharide deacetylase
HBN41_RS06410	COG1649	PFAM Uncharacterised BCR, COG1649
HBN41_RS06415	COG1215	transferase activity, transferring glycosyl groups
HBN41_RS06420	COG3658	cytochrome
HBN41_RS06430	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBN41_RS06445	COG0583	DNA-binding transcription factor activity
HBN41_RS06465	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBN41_RS06470	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBN41_RS06485	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS06490	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBN41_RS06495	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN41_RS06520	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
HBN41_RS06525	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
HBN41_RS06535	COG2205	protein histidine kinase activity
HBN41_RS06540	COG0745	RESPONSE REGULATOR receiver
HBN41_RS06545	COG0174	glutamine synthetase
HBN41_RS06565	COG0729	surface antigen
HBN41_RS06590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBN41_RS06595	COG2814	Major facilitator Superfamily
HBN41_RS06610	COG0583	DNA-binding transcription factor activity
HBN41_RS06625	COG1187	pseudouridine synthase activity
HBN41_RS06645	COG0802	atpase or kinase
HBN41_RS06650	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
HBN41_RS06660	COG1923	regulation of RNA biosynthetic process
HBN41_RS06665	COG0697	spore germination
HBN41_RS06680	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBN41_RS06690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBN41_RS06695	COG0519	Catalyzes the synthesis of GMP from XMP
HBN41_RS06695	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBN41_RS06700	COG4302	ethanolamine ammonia-lyase activity
HBN41_RS06705	COG4303	Ethanolamine ammonia lyase large subunit
HBN41_RS06710	COG0531	amino acid
HBN41_RS06730	COG1454	alcohol dehydrogenase
HBN41_RS06735	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBN41_RS06745	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
HBN41_RS06765	COG0308	aminopeptidase N
HBN41_RS06795	COG1605	Chorismate mutase
HBN41_RS06810	COG1309	transcriptional regulator
HBN41_RS06820	COG0668	transmembrane transport
HBN41_RS06855	COG4773	Receptor
HBN41_RS06875	COG0488	(ABC) transporter
HBN41_RS06880	COG0589	response to stress
HBN41_RS06905	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HBN41_RS06915	COG3135	benzoate transporter
HBN41_RS06920	COG1522	sequence-specific DNA binding
HBN41_RS06930	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HBN41_RS06935	COG0583	DNA-binding transcription factor activity
HBN41_RS06945	COG0183	Belongs to the thiolase family
HBN41_RS06955	COG2030	dehydratase
HBN41_RS06975	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HBN41_RS06985	COG0824	Thioesterase
HBN41_RS06990	COG1454	alcohol dehydrogenase
HBN41_RS07000	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HBN41_RS07020	COG0069	glutamate synthase activity
HBN41_RS07195	COG5410	chromosome segregation
HBN41_RS07315	COG0739	heme binding
HBN41_RS07380	COG2814	Major facilitator Superfamily
HBN41_RS07395	COG0511	ligase activity, forming carbon-carbon bonds
HBN41_RS07415	COG1116	anion transmembrane transporter activity
HBN41_RS07415	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBN41_RS07420	COG0745	RESPONSE REGULATOR receiver
HBN41_RS07430	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN41_RS07430	COG2146	nitrite reductase [NAD(P)H] activity
HBN41_RS07435	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN41_RS07440	COG0243	molybdopterin cofactor binding
HBN41_RS07450	COG0243	molybdopterin cofactor binding
HBN41_RS07455	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
HBN41_RS07470	COG0521	Mo-molybdopterin cofactor biosynthetic process
HBN41_RS07470	COG0315	cyclic pyranopterin monophosphate synthase activity
HBN41_RS07475	COG0303	'Molybdopterin
HBN41_RS07485	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBN41_RS07490	COG0697	spore germination
HBN41_RS07510	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
HBN41_RS07515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBN41_RS07580	COG2204	response regulator
HBN41_RS07585	COG3852	Histidine kinase
HBN41_RS07605	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
HBN41_RS07610	COG0575	Belongs to the CDS family
HBN41_RS07645	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBN41_RS07660	COG2137	regulation of response to DNA damage stimulus
HBN41_RS07670	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
HBN41_RS07675	COG1011	Hydrolase
HBN41_RS07700	COG1522	sequence-specific DNA binding
HBN41_RS07710	COG1113	amino acid transport
HBN41_RS07725	COG0659	secondary active sulfate transmembrane transporter activity
HBN41_RS07730	COG2135	peptidase activity
HBN41_RS07745	COG3300	MHYT domain
HBN41_RS07745	COG5001	Diguanylate cyclase
HBN41_RS07765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
HBN41_RS07765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBN41_RS07765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HBN41_RS07770	COG1105	Belongs to the carbohydrate kinase PfkB family
HBN41_RS07775	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HBN41_RS07775	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBN41_RS07805	COG0024	Methionine aminopeptidase
HBN41_RS07810	COG0583	DNA-binding transcription factor activity
HBN41_RS07820	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
HBN41_RS07825	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
HBN41_RS07830	COG0517	IMP dehydrogenase activity
HBN41_RS07830	COG0516	GMP reductase activity
HBN41_RS07855	COG0552	protein localization to endoplasmic reticulum
HBN41_RS07865	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
HBN41_RS07880	COG4890	Cyd operon protein YbgT
HBN41_RS07885	COG1294	oxidase, subunit
HBN41_RS07900	COG1585	Membrane protein implicated in regulation of membrane protease activity
HBN41_RS07910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HBN41_RS07915	COG4774	siderophore transport
HBN41_RS07930	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
HBN41_RS07935	COG0569	domain protein
HBN41_RS07940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HBN41_RS07970	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
HBN41_RS07975	COG0542	response to heat
HBN41_RS08000	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN41_RS08000	COG1902	pentaerythritol trinitrate reductase activity
HBN41_RS08045	COG2323	membrane
HBN41_RS08050	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
HBN41_RS08060	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBN41_RS08065	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBN41_RS08070	COG0183	Belongs to the thiolase family
HBN41_RS08075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HBN41_RS08080	COG0596	Alpha beta hydrolase
HBN41_RS08085	COG2271	Major facilitator Superfamily
HBN41_RS08090	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBN41_RS08095	COG3485	protocatechuate 3,4-dioxygenase
HBN41_RS08100	COG3485	protocatechuate 3,4-dioxygenase
HBN41_RS08105	COG0710	3-dehydroquinate dehydratase activity
HBN41_RS08110	COG3420	alginic acid biosynthetic process
HBN41_RS08115	COG3659	wide pore channel activity
HBN41_RS08120	COG4993	Dehydrogenase
HBN41_RS08130	COG2391	methyltransferase activity
HBN41_RS08145	COG1414	Transcriptional regulator
HBN41_RS08150	COG0583	DNA-binding transcription factor activity
HBN41_RS08155	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS08180	COG0640	Transcriptional regulator
HBN41_RS08190	COG2850	peptidyl-arginine hydroxylation
HBN41_RS08195	COG0424	maF-like protein
HBN41_RS08215	COG0191	fructose-bisphosphate aldolase activity
HBN41_RS08220	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBN41_RS08235	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBN41_RS08245	COG1192	Involved in chromosome partitioning
HBN41_RS08250	COG1475	DNA binding
HBN41_RS08255	COG0811	peptide transport
HBN41_RS08265	COG1132	(ABC) transporter
HBN41_RS08270	COG1663	tetraacyldisaccharide 4'-kinase activity
HBN41_RS08290	COG0084	hydrolase, TatD family'
HBN41_RS08355	COG0776	regulation of translation
HBN41_RS08385	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
HBN41_RS08390	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
HBN41_RS08440	COG0339	signal peptide processing
HBN41_RS08450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HBN41_RS08485	COG0702	epimerase
HBN41_RS08490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBN41_RS08510	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
HBN41_RS08540	COG0316	Belongs to the HesB IscA family
HBN41_RS08545	COG0822	iron-sulfur transferase activity
HBN41_RS08570	COG0776	regulation of translation
HBN41_RS08575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
HBN41_RS08580	COG2207	Transcriptional regulator
HBN41_RS08585	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBN41_RS08590	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS08595	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS08610	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HBN41_RS08630	COG4264	IucA IucC family
HBN41_RS08635	COG4264	IucA IucC family
HBN41_RS08690	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
HBN41_RS08710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HBN41_RS08715	COG0730	response to heat
HBN41_RS08735	COG4773	Receptor
HBN41_RS08740	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
HBN41_RS08755	COG1131	(ABC) transporter
HBN41_RS08760	COG0842	Transport permease protein
HBN41_RS08765	COG0842	Transport permease protein
HBN41_RS08820	COG2226	methyltransferase
HBN41_RS08845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
HBN41_RS08880	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HBN41_RS08890	COG0133	tryptophan synthase activity
HBN41_RS08905	COG3706	GGDEF domain
HBN41_RS08920	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
HBN41_RS08925	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
HBN41_RS08930	COG0022	dehydrogenase e1 component
HBN41_RS08935	COG0508	dehydrogenase complex catalyzes the overall conversion of
HBN41_RS08940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HBN41_RS08950	COG1063	alcohol dehydrogenase
HBN41_RS08955	COG3781	membrane
HBN41_RS08965	COG3453	Protein conserved in bacteria
HBN41_RS08965	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBN41_RS08975	COG0730	response to heat
HBN41_RS08990	COG2207	Transcriptional regulator
HBN41_RS08990	COG3708	Transcriptional regulator
HBN41_RS08995	COG1733	regulation of RNA biosynthetic process
HBN41_RS09000	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
HBN41_RS09010	COG2188	Transcriptional regulator
HBN41_RS09025	COG4521	taurine ABC transporter
HBN41_RS09030	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBN41_RS09050	COG0477	Major facilitator Superfamily
HBN41_RS09060	COG1027	Aspartate ammonia-lyase
HBN41_RS09075	COG0583	DNA-binding transcription factor activity
HBN41_RS09080	COG0583	DNA-binding transcription factor activity
HBN41_RS09085	COG0183	Belongs to the thiolase family
HBN41_RS09090	COG2031	fatty acid transporter
HBN41_RS09095	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBN41_RS09105	COG0583	DNA-binding transcription factor activity
HBN41_RS09115	COG2610	gluconate transmembrane transporter activity
HBN41_RS09120	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS09130	COG2207	Transcriptional regulator
HBN41_RS09145	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS09170	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBN41_RS09170	COG0543	2 iron, 2 sulfur cluster binding
HBN41_RS09175	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBN41_RS09180	COG4638	Rieske (2fe-2S)
HBN41_RS09190	COG0725	ABC transporter, periplasmic molybdate-binding protein
HBN41_RS09195	COG4149	molybdate abc transporter
HBN41_RS09200	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
HBN41_RS09205	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS09210	COG3433	isochorismatase activity
HBN41_RS09210	COG1535	isochorismatase
HBN41_RS09275	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
HBN41_RS09295	COG0753	catalase activity
HBN41_RS09305	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
HBN41_RS09335	COG3539	Fimbrial protein
HBN41_RS09355	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBN41_RS09375	COG2072	flavoprotein involved in K transport
HBN41_RS09385	COG1538	Outer membrane efflux protein
HBN41_RS09390	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
HBN41_RS09395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN41_RS09400	COG0745	RESPONSE REGULATOR receiver
HBN41_RS09405	COG2205	protein histidine kinase activity
HBN41_RS09415	COG2207	Transcriptional regulator
HBN41_RS09430	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS09480	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
HBN41_RS09600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBN41_RS09620	COG1120	ATPase activity
HBN41_RS09635	COG1064	alcohol dehydrogenase
HBN41_RS09650	COG2207	Transcriptional regulator
HBN41_RS09655	COG2084	Dehydrogenase
HBN41_RS09665	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
HBN41_RS09670	COG0583	DNA-binding transcription factor activity
HBN41_RS09680	COG0129	dihydroxy-acid dehydratase activity
HBN41_RS09685	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS09700	COG1566	PFAM secretion protein HlyD family protein
HBN41_RS09720	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
HBN41_RS09750	COG0583	DNA-binding transcription factor activity
HBN41_RS09765	COG2188	Transcriptional regulator
HBN41_RS09795	COG3210	domain, Protein
HBN41_RS09800	COG2831	hemolysin activation secretion protein
HBN41_RS09810	COG1473	amidohydrolase
HBN41_RS09820	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBN41_RS09820	COG0475	glutathione-regulated potassium exporter activity
HBN41_RS09830	COG0583	DNA-binding transcription factor activity
HBN41_RS09835	COG1335	isochorismatase
HBN41_RS09845	COG1309	transcriptional regulator
HBN41_RS09875	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
HBN41_RS09885	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN41_RS09885	COG1902	pentaerythritol trinitrate reductase activity
HBN41_RS09890	COG1846	Transcriptional regulator
HBN41_RS09910	COG0753	catalase activity
HBN41_RS09925	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS09940	COG3162	membrane
HBN41_RS09950	COG3829	transcription factor binding
HBN41_RS09955	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS09960	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS09980	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS10000	COG2186	Transcriptional regulator
HBN41_RS10010	COG0583	DNA-binding transcription factor activity
HBN41_RS10015	COG4948	Mandelate Racemase Muconate Lactonizing
HBN41_RS10020	COG4829	muconolactone delta-isomerase
HBN41_RS10030	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBN41_RS10035	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBN41_RS10040	COG0183	Belongs to the thiolase family
HBN41_RS10045	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBN41_RS10055	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS10065	COG3733	amine oxidase
HBN41_RS10075	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN41_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS10095	COG4638	Rieske (2fe-2S)
HBN41_RS10115	COG0154	amidase activity
HBN41_RS10125	COG2814	Major facilitator Superfamily
HBN41_RS10150	COG3619	membrane
HBN41_RS10155	COG3122	Protein conserved in bacteria
HBN41_RS10160	COG1132	(ABC) transporter
HBN41_RS10180	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HBN41_RS10185	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HBN41_RS10195	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBN41_RS10195	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
HBN41_RS10195	COG0506	proline dehydrogenase activity
HBN41_RS10200	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
HBN41_RS10215	COG3698	Phosphodiester glycosidase
HBN41_RS10225	COG2353	YceI-like domain
HBN41_RS10235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
HBN41_RS10280	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
HBN41_RS10280	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
HBN41_RS10305	COG3539	Fimbrial protein
HBN41_RS10310	COG3121	Chaperone
HBN41_RS10335	COG0697	spore germination
HBN41_RS10345	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBN41_RS10355	COG0583	DNA-binding transcription factor activity
HBN41_RS10375	COG1309	transcriptional regulator
HBN41_RS10390	COG1522	sequence-specific DNA binding
HBN41_RS10400	COG1126	abc transporter atp-binding protein
HBN41_RS10405	COG0765	amino acid transport
HBN41_RS10410	COG0765	amino acid transport
HBN41_RS10440	COG1464	Belongs to the NlpA lipoprotein family
HBN41_RS10450	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HBN41_RS10455	COG2011	ABC-type metal ion transport system permease component
HBN41_RS10460	COG0012	GTP binding
HBN41_RS10485	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
HBN41_RS10525	COG0386	Belongs to the glutathione peroxidase family
HBN41_RS10535	COG0436	Aminotransferase
HBN41_RS10575	COG3634	alkyl hydroperoxide reductase activity
HBN41_RS10590	COG0583	DNA-binding transcription factor activity
HBN41_RS10595	COG0798	PFAM Bile acid sodium symporter
HBN41_RS10600	COG0640	Transcriptional regulator
HBN41_RS10615	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
HBN41_RS10625	COG0583	DNA-binding transcription factor activity
HBN41_RS10635	COG1953	Uracil, thiamine, allantoin
HBN41_RS10645	COG2175	clavaminate synthase activity
HBN41_RS10650	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBN41_RS10655	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
HBN41_RS10660	COG4521	taurine ABC transporter
HBN41_RS10670	COG0477	Major facilitator Superfamily
HBN41_RS10690	COG1271	oxidase subunit
HBN41_RS10695	COG1294	oxidase, subunit
HBN41_RS10705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HBN41_RS10725	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HBN41_RS10745	COG3052	prosthetic group binding
HBN41_RS10750	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
HBN41_RS10760	COG2814	Major facilitator Superfamily
HBN41_RS10780	COG1346	cytolysis
HBN41_RS10790	COG0583	DNA-binding transcription factor activity
HBN41_RS10795	COG0625	glutathione transferase activity
HBN41_RS10800	COG0625	glutathione transferase activity
HBN41_RS10805	COG0583	DNA-binding transcription factor activity
HBN41_RS10820	COG1045	serine acetyltransferase
HBN41_RS10825	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HBN41_RS10830	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HBN41_RS10840	COG1280	lysine exporter protein (LysE YggA)
HBN41_RS10855	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBN41_RS10860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBN41_RS10865	COG1126	abc transporter atp-binding protein
HBN41_RS10870	COG0765	amino acid transport
HBN41_RS10875	COG0765	amino acid transport
HBN41_RS10895	COG2205	protein histidine kinase activity
HBN41_RS10895	COG0784	Response regulator, receiver
HBN41_RS10915	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBN41_RS10935	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS10985	COG0583	DNA-binding transcription factor activity
HBN41_RS11005	COG0318	PFAM AMP-dependent synthetase and ligase
HBN41_RS11010	COG1309	transcriptional regulator
HBN41_RS11015	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS11020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HBN41_RS11025	COG1024	Enoyl-CoA hydratase
HBN41_RS11030	COG4770	biotin carboxylase activity
HBN41_RS11040	COG0583	DNA-binding transcription factor activity
HBN41_RS11055	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS11065	COG2814	Major facilitator Superfamily
HBN41_RS11075	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
HBN41_RS11080	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
HBN41_RS11085	COG2814	Major facilitator Superfamily
HBN41_RS11090	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS11095	COG1024	Enoyl-CoA hydratase
HBN41_RS11100	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS11105	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBN41_RS11110	COG0183	Belongs to the thiolase family
HBN41_RS11120	COG2814	Major facilitator Superfamily
HBN41_RS11130	COG1024	Enoyl-CoA hydratase
HBN41_RS11145	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS11150	COG2814	Major facilitator Superfamily
HBN41_RS11155	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HBN41_RS11160	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
HBN41_RS11175	COG3842	ATPase activity
HBN41_RS11180	COG1840	ABC-type Fe3 transport system, periplasmic component
HBN41_RS11190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN41_RS11195	COG1414	Transcriptional regulator
HBN41_RS11205	COG0583	DNA-binding transcription factor activity
HBN41_RS11210	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
HBN41_RS11215	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS11225	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
HBN41_RS11235	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS11255	COG1061	Type III restriction enzyme res subunit
HBN41_RS11280	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN41_RS11285	COG2267	carboxylic ester hydrolase activity
HBN41_RS11305	COG3038	cytochrome b561
HBN41_RS11310	COG0753	catalase activity
HBN41_RS11345	COG2050	protein possibly involved in aromatic compounds catabolism
HBN41_RS11355	COG3327	negative regulation of DNA-templated transcription, initiation
HBN41_RS11360	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
HBN41_RS11365	COG0183	Belongs to the thiolase family
HBN41_RS11370	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBN41_RS11375	COG1024	Enoyl-CoA hydratase
HBN41_RS11380	COG1024	Enoyl-CoA hydratase
HBN41_RS11385	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
HBN41_RS11390	COG2151	metal-sulfur cluster biosynthetic enzyme
HBN41_RS11395	COG3396	Phenylacetate-CoA oxygenase
HBN41_RS11400	COG3460	Phenylacetate-CoA oxygenase
HBN41_RS11405	COG3396	Phenylacetate-CoA oxygenase
HBN41_RS11410	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS11410	COG2030	dehydratase
HBN41_RS11415	COG1760	l-serine dehydratase
HBN41_RS11420	COG0531	amino acid
HBN41_RS11425	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS11440	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN41_RS11450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
HBN41_RS11470	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBN41_RS11480	COG0789	Transcriptional regulator
HBN41_RS11495	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
HBN41_RS11510	COG2807	transmembrane transport
HBN41_RS11515	COG0590	tRNA wobble adenosine to inosine editing
HBN41_RS11630	COG1116	anion transmembrane transporter activity
HBN41_RS11635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HBN41_RS11645	COG0864	Transcriptional regulator
HBN41_RS11665	COG2249	NAD(P)H dehydrogenase (quinone) activity
HBN41_RS11670	COG0439	Biotin carboxylase
HBN41_RS11685	COG1063	alcohol dehydrogenase
HBN41_RS11695	COG1309	transcriptional regulator
HBN41_RS11715	COG0038	chloride channel
HBN41_RS11720	COG4770	biotin carboxylase activity
HBN41_RS11740	COG1914	H( )-stimulated, divalent metal cation uptake system
HBN41_RS11745	COG0583	DNA-binding transcription factor activity
HBN41_RS11760	COG3209	COG3209 Rhs family protein
HBN41_RS11765	COG3501	Rhs element vgr protein
HBN41_RS11795	COG1250	3-hydroxyacyl-CoA dehydrogenase
HBN41_RS11815	COG2814	Major facilitator Superfamily
HBN41_RS11825	COG1560	Kdo2-lipid A biosynthetic process
HBN41_RS11835	COG5006	permease, DMT superfamily
HBN41_RS11840	COG1522	sequence-specific DNA binding
HBN41_RS11855	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
HBN41_RS11865	COG4122	O-methyltransferase activity
HBN41_RS11895	COG1538	Outer membrane efflux protein
HBN41_RS11905	COG1137	ATPase activity
HBN41_RS11910	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
HBN41_RS11920	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
HBN41_RS11925	COG0517	IMP dehydrogenase activity
HBN41_RS11925	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
HBN41_RS11965	COG2814	Major facilitator Superfamily
HBN41_RS12000	COG1278	Cold shock
HBN41_RS12005	COG1280	lysine exporter protein (LysE YggA)
HBN41_RS12040	COG1570	exodeoxyribonuclease VII activity
HBN41_RS12090	COG0583	DNA-binding transcription factor activity
HBN41_RS12095	COG4638	Rieske (2fe-2S)
HBN41_RS12100	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
HBN41_RS12105	COG0633	Ferredoxin
HBN41_RS12105	COG0543	2 iron, 2 sulfur cluster binding
HBN41_RS12110	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS12115	COG3135	benzoate transporter
HBN41_RS12120	COG2814	Major facilitator Superfamily
HBN41_RS12135	COG1643	Atp-dependent helicase
HBN41_RS12140	COG0450	alkyl hydroperoxide reductase
HBN41_RS12150	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
HBN41_RS12160	COG3634	alkyl hydroperoxide reductase activity
HBN41_RS12180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
HBN41_RS12185	COG0625	glutathione transferase activity
HBN41_RS12195	COG2885	chlorophyll binding
HBN41_RS12230	COG0542	response to heat
HBN41_RS12245	COG1765	OsmC-like protein
HBN41_RS12260	COG0667	Aldo Keto reductase
HBN41_RS12275	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
HBN41_RS12285	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
HBN41_RS12295	COG0527	aspartate kinase activity
HBN41_RS12305	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HBN41_RS12315	COG3038	cytochrome b561
HBN41_RS12320	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
HBN41_RS12325	COG2252	PERMEase
HBN41_RS12335	COG2072	flavoprotein involved in K transport
HBN41_RS12350	COG1741	Belongs to the pirin family
HBN41_RS12355	COG1309	transcriptional regulator
HBN41_RS12375	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN41_RS12375	COG1902	pentaerythritol trinitrate reductase activity
HBN41_RS12385	COG4251	negative regulation of phosphorylation
HBN41_RS12385	COG3706	GGDEF domain
HBN41_RS12385	COG5001	Diguanylate cyclase
HBN41_RS12385	COG2203	Gaf domain
HBN41_RS12395	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBN41_RS12415	COG4172	Belongs to the ABC transporter superfamily
HBN41_RS12420	COG4239	(ABC) transporter, permease
HBN41_RS12425	COG4174	ABC transporter (Permease)
HBN41_RS12435	COG0741	lytic transglycosylase activity
HBN41_RS12435	COG1388	LysM domain
HBN41_RS12435	COG0741	lytic transglycosylase activity
HBN41_RS12435	COG1388	LysM domain
HBN41_RS12440	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBN41_RS12480	COG0583	DNA-binding transcription factor activity
HBN41_RS12485	COG1279	arginine transmembrane transporter activity
HBN41_RS12505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN41_RS12510	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN41_RS12515	COG0006	proline dipeptidase activity
HBN41_RS12550	COG2194	sulfuric ester hydrolase activity
HBN41_RS12595	COG0739	heme binding
HBN41_RS13025	COG4695	Portal protein
HBN41_RS13120	COG0305	Participates in initiation and elongation during chromosome replication
HBN41_RS13135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
HBN41_RS13190	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HBN41_RS13215	COG3384	dioxygenase
HBN41_RS13225	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HBN41_RS13230	COG2878	Part of a membrane complex involved in electron transport
HBN41_RS13235	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
HBN41_RS13260	COG0768	penicillin binding
HBN41_RS13265	COG0742	ribosomal rna small subunit methyltransferase
HBN41_RS13280	COG0830	nickel cation binding
HBN41_RS13290	COG0804	urea catabolic process
HBN41_RS13330	COG1253	flavin adenine dinucleotide binding
HBN41_RS13335	COG2851	Citrate transporter
HBN41_RS13390	COG1773	rubredoxin
HBN41_RS13395	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
HBN41_RS13405	COG0583	DNA-binding transcription factor activity
HBN41_RS13430	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
HBN41_RS13435	COG4181	ATPase activity
HBN41_RS13480	COG1262	PFAM Formylglycine-generating sulfatase enzyme
HBN41_RS13500	COG0306	phosphate transporter
HBN41_RS13510	COG3958	Transketolase
HBN41_RS13515	COG3959	Transketolase, thiamine diphosphate binding domain
HBN41_RS13520	COG2271	Major facilitator Superfamily
HBN41_RS13525	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS13530	COG0583	DNA-binding transcription factor activity
HBN41_RS13545	COG2223	nitrite transmembrane transporter activity
HBN41_RS13550	COG2207	Transcriptional regulator
HBN41_RS13555	COG2066	Belongs to the glutaminase family
HBN41_RS13560	COG0242	peptide deformylase activity
HBN41_RS13565	COG0477	Major facilitator Superfamily
HBN41_RS13575	COG0028	Belongs to the TPP enzyme family
HBN41_RS13590	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS13595	COG2267	carboxylic ester hydrolase activity
HBN41_RS13605	COG2271	Major facilitator Superfamily
HBN41_RS13610	COG0446	pyridine nucleotide-disulphide oxidoreductase
HBN41_RS13620	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS13640	COG1414	Transcriptional regulator
HBN41_RS13655	COG1024	Enoyl-CoA hydratase
HBN41_RS13665	COG1215	transferase activity, transferring glycosyl groups
HBN41_RS13670	COG1649	PFAM Uncharacterised BCR, COG1649
HBN41_RS13670	COG0726	polysaccharide deacetylase
HBN41_RS13680	COG4681	YaeQ
HBN41_RS13690	COG0523	cobalamin synthesis protein
HBN41_RS13700	COG1607	acyl-coa hydrolase
HBN41_RS13710	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN41_RS13715	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
HBN41_RS13720	COG1309	transcriptional regulator
HBN41_RS13745	COG2040	homocysteine
HBN41_RS13750	COG0531	amino acid
HBN41_RS13805	COG1595	DNA-templated transcription, initiation
HBN41_RS13815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBN41_RS13820	COG0477	Major facilitator Superfamily
HBN41_RS13840	COG0084	hydrolase, TatD family'
HBN41_RS13875	COG0629	single-stranded DNA binding
HBN41_RS13930	COG0582	viral genome integration into host DNA
HBN41_RS14025	COG0592	DNA-directed DNA polymerase activity
HBN41_RS14065	COG2026	Addiction module toxin, RelE StbE family
HBN41_RS14260	COG1484	DNA-dependent DNA replication
HBN41_RS14350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HBN41_RS14420	COG0405	Gamma-glutamyltransferase
HBN41_RS14425	COG2814	Major facilitator Superfamily
HBN41_RS14435	COG2050	protein possibly involved in aromatic compounds catabolism
HBN41_RS14450	COG1090	epimerase
HBN41_RS14470	COG0420	3'-5' exonuclease activity
HBN41_RS14495	COG0735	belongs to the Fur family
HBN41_RS14500	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HBN41_RS14520	COG0121	glutamine amidotransferase
HBN41_RS14535	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBN41_RS14545	COG0210	DNA helicase
HBN41_RS14550	COG2885	chlorophyll binding
HBN41_RS14555	COG0204	Acyl-transferase
HBN41_RS14570	COG2894	cell division
HBN41_RS14595	COG1280	lysine exporter protein (LysE YggA)
HBN41_RS14600	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
HBN41_RS14600	COG1674	ftsk spoiiie
HBN41_RS14605	COG0492	ferredoxin-NADP+ reductase activity
HBN41_RS14610	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
HBN41_RS14620	COG0456	acetyltransferase
HBN41_RS14680	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBN41_RS14680	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
HBN41_RS14700	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS14720	COG0473	3-isopropylmalate dehydrogenase activity
HBN41_RS14725	COG0583	DNA-binding transcription factor activity
HBN41_RS14745	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
HBN41_RS14770	COG0564	pseudouridine synthase activity
HBN41_RS14780	COG0358	DNA primase activity
HBN41_RS14795	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
HBN41_RS14825	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
HBN41_RS14855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HBN41_RS14865	COG0351	phosphomethylpyrimidine kinase
HBN41_RS14865	COG0352	thiamine-phosphate diphosphorylase activity
HBN41_RS14865	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HBN41_RS14870	COG1652	LysM domain
HBN41_RS14895	COG1399	metal-binding, possibly nucleic acid-binding protein
HBN41_RS14900	COG3101	peptidyl-lysine hydroxylation
HBN41_RS14905	COG0009	L-threonylcarbamoyladenylate synthase
HBN41_RS14910	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HBN41_RS14915	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HBN41_RS14930	COG4106	trans-aconitate 2-methyltransferase activity
HBN41_RS14945	COG0596	Alpha beta hydrolase
HBN41_RS14945	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBN41_RS14945	COG2226	methyltransferase
HBN41_RS14950	COG1877	trehalose-phosphatase activity
HBN41_RS14955	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
HBN41_RS14960	COG2223	nitrite transmembrane transporter activity
HBN41_RS14980	COG1196	nuclear chromosome segregation
HBN41_RS14990	COG0730	response to heat
HBN41_RS15005	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HBN41_RS15015	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBN41_RS15065	COG0489	protein tyrosine kinase activity
HBN41_RS15075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBN41_RS15075	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBN41_RS15105	COG2515	1-aminocyclopropane-1-carboxylate deaminase
HBN41_RS15110	COG2081	HI0933 family
HBN41_RS15120	COG0668	transmembrane transport
HBN41_RS15140	COG0583	DNA-binding transcription factor activity
HBN41_RS15160	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
HBN41_RS15165	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBN41_RS15195	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HBN41_RS15230	COG2205	protein histidine kinase activity
HBN41_RS15235	COG0745	RESPONSE REGULATOR receiver
HBN41_RS15255	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HBN41_RS15265	COG2205	protein histidine kinase activity
HBN41_RS15335	COG4993	Dehydrogenase
HBN41_RS15355	COG0384	phenazine biosynthesis protein PhzF
HBN41_RS15375	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
HBN41_RS15390	COG0583	DNA-binding transcription factor activity
HBN41_RS15410	COG1473	amidohydrolase
HBN41_RS15420	COG0583	DNA-binding transcription factor activity
HBN41_RS15435	COG0583	DNA-binding transcription factor activity
HBN41_RS15440	COG1053	succinate dehydrogenase
HBN41_RS15450	COG1804	L-carnitine dehydratase bile acid-inducible protein F
HBN41_RS15455	COG2814	Major facilitator Superfamily
HBN41_RS15460	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS15465	COG0583	DNA-binding transcription factor activity
HBN41_RS15470	COG1063	alcohol dehydrogenase
HBN41_RS15500	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HBN41_RS15505	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
HBN41_RS15510	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBN41_RS15525	COG3667	copper resistance
HBN41_RS15530	COG2132	Multicopper oxidase
HBN41_RS15540	COG0561	phosphatase activity
HBN41_RS15545	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HBN41_RS15570	COG1214	PFAM Peptidase M22, glycoprotease
HBN41_RS15620	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
HBN41_RS15630	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
HBN41_RS15635	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
HBN41_RS15640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HBN41_RS15700	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HBN41_RS15710	COG1846	Transcriptional regulator
HBN41_RS15715	COG1764	response to oxidative stress
HBN41_RS15765	COG0037	tRNA processing
HBN41_RS15775	COG0248	Ppx GppA phosphatase
HBN41_RS15805	COG0072	phenylalanine-tRNA ligase activity
HBN41_RS15845	COG1238	metal cluster binding
HBN41_RS15850	COG0625	glutathione transferase activity
HBN41_RS15865	COG0318	PFAM AMP-dependent synthetase and ligase
HBN41_RS15870	COG3028	Belongs to the UPF0307 family
HBN41_RS15875	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
HBN41_RS15895	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HBN41_RS15900	COG0617	tRNA 3'-terminal CCA addition
HBN41_RS15905	COG1555	photosystem II stabilization
HBN41_RS15910	COG3956	TIGRFAM MazG family protein
HBN41_RS15920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HBN41_RS15940	COG5002	protein histidine kinase activity
HBN41_RS15940	COG2205	protein histidine kinase activity
HBN41_RS15940	COG0784	Response regulator, receiver
HBN41_RS15945	COG1024	Enoyl-CoA hydratase
HBN41_RS15950	COG2084	Dehydrogenase
HBN41_RS15955	COG3622	Belongs to the hyi family
HBN41_RS15985	COG0697	spore germination
HBN41_RS15995	COG2814	Major facilitator Superfamily
HBN41_RS16000	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
HBN41_RS16010	COG0583	DNA-binding transcription factor activity
HBN41_RS16020	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
HBN41_RS16035	COG0084	hydrolase, TatD family'
HBN41_RS16050	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
HBN41_RS16080	COG0440	acetolactate synthase activity
HBN41_RS16085	COG0028	Belongs to the TPP enzyme family
HBN41_RS16110	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
HBN41_RS16115	COG0577	efflux transmembrane transporter activity
HBN41_RS16115	COG1136	(ABC) transporter
HBN41_RS16120	COG1538	Outer membrane efflux protein
HBN41_RS16135	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
HBN41_RS16140	COG1162	GTPase activity
HBN41_RS16150	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
HBN41_RS16170	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
HBN41_RS16175	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS16215	COG2986	histidine ammonia-lyase
HBN41_RS16230	COG0318	PFAM AMP-dependent synthetase and ligase
HBN41_RS16240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBN41_RS16285	COG1426	Protein conserved in bacteria
HBN41_RS16320	COG0793	Belongs to the peptidase S41A family
HBN41_RS16335	COG2267	carboxylic ester hydrolase activity
HBN41_RS16345	COG1012	belongs to the aldehyde dehydrogenase family
HBN41_RS16350	COG3265	gluconokinase activity
HBN41_RS16360	COG0800	Aldolase
HBN41_RS16375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HBN41_RS16380	COG0857	belongs to the CobB CobQ family
HBN41_RS16380	COG0280	phosphate acetyltransferase
HBN41_RS16385	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
HBN41_RS16385	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
HBN41_RS16405	COG0740	serine-type endopeptidase activity
HBN41_RS16435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
HBN41_RS16445	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
HBN41_RS16445	COG2813	Specifically methylates the guanine in position
HBN41_RS16545	COG0788	formyltetrahydrofolate deformylase activity
HBN41_RS16570	COG4651	solute:proton antiporter activity
HBN41_RS16570	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBN41_RS16590	COG0724	RNA recognition motif
HBN41_RS16595	COG0210	DNA helicase
HBN41_RS16620	COG1733	regulation of RNA biosynthetic process
HBN41_RS16630	COG2900	Belongs to the SlyX family
HBN41_RS16640	COG1280	lysine exporter protein (LysE YggA)
HBN41_RS16645	COG1560	Kdo2-lipid A biosynthetic process
HBN41_RS16655	COG1301	dicarboxylic acid transport
HBN41_RS16710	COG0473	3-isopropylmalate dehydrogenase activity
HBN41_RS16775	COG0583	DNA-binding transcription factor activity
HBN41_RS16785	COG0625	glutathione transferase activity
HBN41_RS16790	COG2378	regulation of single-species biofilm formation
HBN41_RS16795	COG0546	phosphoglycolate phosphatase activity
HBN41_RS16810	COG1530	ribonuclease E activity
HBN41_RS16815	COG0318	PFAM AMP-dependent synthetase and ligase
HBN41_RS16830	COG0583	DNA-binding transcription factor activity
HBN41_RS16835	COG4221	oxidoreductase activity
HBN41_RS16840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
HBN41_RS16850	COG0534	Mate efflux family protein
HBN41_RS16865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
HBN41_RS16905	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
HBN41_RS16910	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
HBN41_RS16925	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
HBN41_RS16935	COG0644	oxidoreductase
HBN41_RS16935	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
HBN41_RS16940	COG0425	Belongs to the sulfur carrier protein TusA family
HBN41_RS16945	COG4535	Mg2 and Co2 transporter CorC
HBN41_RS16955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
HBN41_RS16975	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HBN41_RS16980	COG0475	glutathione-regulated potassium exporter activity
HBN41_RS16980	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
HBN41_RS16985	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
HBN41_RS16995	COG0484	heat shock protein binding
HBN41_RS17000	COG0789	Transcriptional regulator
HBN41_RS17005	COG0598	Magnesium transport protein CorA
HBN41_RS17030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HBN41_RS17035	COG1074	ATP-dependent DNA helicase activity
HBN41_RS17040	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
HBN41_RS17060	COG2226	methyltransferase
HBN41_RS17075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
HBN41_RS17080	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
HBN41_RS17095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
HBN41_RS17095	COG2111	Na H antiporter
HBN41_RS17100	COG1006	Multisubunit Na H antiporter MnhC subunit
HBN41_RS17105	COG0651	ATP synthesis coupled electron transport
HBN41_RS17115	COG2212	antiporter activity
HBN41_RS17135	COG0195	Participates in both transcription termination and antitermination
HBN41_RS17185	COG0237	dephospho-CoA kinase activity
HBN41_RS17195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HBN41_RS17210	COG0497	DNA recombination
HBN41_RS17220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
HBN41_RS17250	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HBN41_RS17250	COG2169	Transcriptional regulator
HBN41_RS17255	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HBN41_RS17320	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
HBN41_RS17335	COG0326	Molecular chaperone. Has ATPase activity
HBN41_RS17350	COG2056	Na+-H+ antiporter family
HBN41_RS17355	COG0596	Alpha beta hydrolase
HBN41_RS17450	COG0546	phosphoglycolate phosphatase activity
HBN41_RS17455	COG1716	ATPase activity
HBN41_RS17500	COG0181	hydroxymethylbilane synthase activity
HBN41_RS17510	COG3275	phosphorelay sensor kinase activity
HBN41_RS17530	COG1538	Outer membrane efflux protein
HBN41_RS17535	COG0697	spore germination
HBN41_RS17560	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
HBN41_RS17565	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
HBN41_RS17570	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
HBN41_RS17575	COG0772	Belongs to the SEDS family
HBN41_RS17600	COG4974	Belongs to the 'phage' integrase family
HBN41_RS17605	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBN41_RS17615	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
HBN41_RS17625	COG2197	response regulator
HBN41_RS17640	COG0793	Belongs to the peptidase S41A family
HBN41_RS17645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
HBN41_RS17650	COG0795	lipopolysaccharide-transporting ATPase activity
HBN41_RS17690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBN41_RS17690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
HBN41_RS17700	COG0004	ammonium transporteR
HBN41_RS17705	COG0347	Belongs to the P(II) protein family
HBN41_RS17715	COG0606	chelatase, subunit chli
HBN41_RS17790	COG1061	Type III restriction enzyme res subunit
HBN41_RS17835	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBN41_RS17870	COG0589	response to stress
HBN41_RS17875	COG0659	secondary active sulfate transmembrane transporter activity
HBN41_RS17905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HBN41_RS17940	COG1061	Type III restriction enzyme res subunit
HBN41_RS17955	COG0659	secondary active sulfate transmembrane transporter activity
HBN41_RS17960	COG0589	response to stress
HBN41_RS18010	COG0606	chelatase, subunit chli
HBN41_RS18025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HBN41_RS18040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HBN41_RS18055	COG0318	PFAM AMP-dependent synthetase and ligase
HBN41_RS18065	COG0477	Major facilitator Superfamily
HBN41_RS18070	COG2860	membrane
HBN41_RS18080	COG1253	flavin adenine dinucleotide binding
HBN41_RS18100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HBN41_RS18135	COG0655	NAD(P)H dehydrogenase (quinone) activity
HBN41_RS18145	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
HBN41_RS18180	COG1309	transcriptional regulator
HBN41_RS18215	COG0758	DNA mediated transformation
HBN41_RS18225	COG0697	spore germination
HBN41_RS18230	COG1309	transcriptional regulator
HBN41_RS18245	COG0386	Belongs to the glutathione peroxidase family
HBN41_RS18310	COG1121	(ABC) transporter
HBN41_RS18315	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HBN41_RS18320	COG1280	lysine exporter protein (LysE YggA)
HBN41_RS18325	COG2837	iron assimilation
HBN41_RS18335	COG0281	malic enzyme
HBN41_RS18380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
HBN41_RS18380	COG0519	Catalyzes the synthesis of GMP from XMP
HBN41_RS18385	COG4399	Belongs to the UPF0754 family
HBN41_RS18390	COG2259	Doxx family
HBN41_RS18395	COG0586	Pfam SNARE associated Golgi protein
HBN41_RS18410	COG1192	Involved in chromosome partitioning
HBN41_RS18420	COG0271	Belongs to the BolA IbaG family
HBN41_RS18440	COG2267	carboxylic ester hydrolase activity
HBN41_RS18460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
HBN41_RS18460	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
HBN41_RS18460	COG3321	synthase
HBN41_RS18460	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
HBN41_RS18465	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS18475	COG2197	response regulator
HBN41_RS18485	COG3916	Acyl-homoserine-lactone synthase
HBN41_RS18490	COG0477	Major facilitator Superfamily
HBN41_RS18495	COG1024	Enoyl-CoA hydratase
HBN41_RS18500	COG1024	Enoyl-CoA hydratase
HBN41_RS18505	COG1960	acyl-CoA dehydrogenase activity
HBN41_RS18510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
HBN41_RS18530	COG1113	amino acid transport
HBN41_RS18535	COG1113	amino acid transport
HBN41_RS18540	COG0251	oxidation-reduction process
HBN41_RS18580	COG0564	pseudouridine synthase activity
HBN41_RS18640	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
HBN41_RS18655	COG1802	Transcriptional regulator
HBN41_RS18665	COG1448	Aminotransferase
HBN41_RS18670	COG0277	FAD linked oxidase domain protein
HBN41_RS18680	COG2186	Transcriptional regulator
HBN41_RS18690	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
HBN41_RS18695	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HBN41_RS18710	COG1210	Utp--glucose-1-phosphate uridylyltransferase
HBN41_RS18725	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HBN41_RS18740	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HBN41_RS18775	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS18785	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS18790	COG1083	cytidylyl-transferase
HBN41_RS18795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
HBN41_RS18805	COG2089	acid synthase
HBN41_RS18810	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
HBN41_RS18815	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
HBN41_RS18825	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
HBN41_RS18855	COG0728	peptidoglycan biosynthetic process
HBN41_RS18860	COG3023	N-Acetylmuramoyl-L-alanine amidase
HBN41_RS18915	COG0546	phosphoglycolate phosphatase activity
HBN41_RS18920	COG1028	Short-chain dehydrogenase reductase Sdr
HBN41_RS18940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBN41_RS18945	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
HBN41_RS18950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
HBN41_RS18955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HBN41_RS18960	COG1116	anion transmembrane transporter activity
HBN41_RS18965	COG1309	transcriptional regulator
HBN41_RS18970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HBN41_RS18980	COG0196	riboflavin kinase activity
HBN41_RS18985	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
HBN41_RS18995	COG1047	Peptidyl-prolyl cis-trans
HBN41_RS19035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
HBN41_RS19090	COG2951	lytic endotransglycosylase activity
HBN41_RS19095	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HBN41_RS19110	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
HBN41_RS19120	COG0671	phosphoesterase, PA-phosphatase related
HBN41_RS19125	COG0861	Integral membrane protein TerC family
HBN41_RS19135	COG0754	glutathionylspermidine amidase activity
HBN41_RS19145	COG0402	S-adenosylhomocysteine deaminase activity
HBN41_RS19160	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
HBN41_RS19165	COG1230	cation diffusion facilitator family transporter
HBN41_RS19180	COG0706	membrane insertase activity