locus-tag	class	description
CUC60_RS00135	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CUC60_RS00190	COG2194	sulfuric ester hydrolase activity
CUC60_RS00560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CUC60_RS00585	COG3384	dioxygenase
CUC60_RS00595	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CUC60_RS00600	COG2878	Part of a membrane complex involved in electron transport
CUC60_RS00605	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CUC60_RS00630	COG0768	penicillin binding
CUC60_RS00635	COG0742	ribosomal rna small subunit methyltransferase
CUC60_RS00650	COG0830	nickel cation binding
CUC60_RS00700	COG1253	flavin adenine dinucleotide binding
CUC60_RS00710	COG2851	Citrate transporter
CUC60_RS00760	COG1773	rubredoxin
CUC60_RS00765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_RS00775	COG0583	DNA-binding transcription factor activity
CUC60_RS00810	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CUC60_RS00815	COG4181	ATPase activity
CUC60_RS00890	COG3958	Transketolase
CUC60_RS00895	COG3959	Transketolase, thiamine diphosphate binding domain
CUC60_RS00900	COG2271	Major facilitator Superfamily
CUC60_RS00905	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS00910	COG0583	DNA-binding transcription factor activity
CUC60_RS00930	COG2223	nitrite transmembrane transporter activity
CUC60_RS00935	COG2207	Transcriptional regulator
CUC60_RS00940	COG2066	Belongs to the glutaminase family
CUC60_RS00945	COG0242	peptide deformylase activity
CUC60_RS00950	COG0477	Major facilitator Superfamily
CUC60_RS00960	COG0028	Belongs to the TPP enzyme family
CUC60_RS00975	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS00980	COG2267	carboxylic ester hydrolase activity
CUC60_RS00990	COG2271	Major facilitator Superfamily
CUC60_RS00995	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_RS01005	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS01025	COG1414	Transcriptional regulator
CUC60_RS01040	COG1024	Enoyl-CoA hydratase
CUC60_RS01050	COG1215	transferase activity, transferring glycosyl groups
CUC60_RS01065	COG4681	YaeQ
CUC60_RS01075	COG0523	cobalamin synthesis protein
CUC60_RS01085	COG1607	acyl-coa hydrolase
CUC60_RS01095	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_RS01100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_RS01105	COG1309	transcriptional regulator
CUC60_RS01130	COG2040	homocysteine
CUC60_RS01135	COG0531	amino acid
CUC60_RS01190	COG1595	DNA-templated transcription, initiation
CUC60_RS01200	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC60_RS01205	COG0477	Major facilitator Superfamily
CUC60_RS01225	COG0084	hydrolase, TatD family'
CUC60_RS01325	COG0592	DNA-directed DNA polymerase activity
CUC60_RS01365	COG2026	Addiction module toxin, RelE StbE family
CUC60_RS01515	COG3755	Protein conserved in bacteria
CUC60_RS01560	COG1484	DNA-dependent DNA replication
CUC60_RS01650	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUC60_RS01715	COG0405	Gamma-glutamyltransferase
CUC60_RS01720	COG2814	Major facilitator Superfamily
CUC60_RS01730	COG2050	protein possibly involved in aromatic compounds catabolism
CUC60_RS01745	COG1090	epimerase
CUC60_RS01770	COG0420	3'-5' exonuclease activity
CUC60_RS01795	COG0735	belongs to the Fur family
CUC60_RS01800	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CUC60_RS01825	COG0121	glutamine amidotransferase
CUC60_RS01840	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC60_RS01850	COG0210	DNA helicase
CUC60_RS01855	COG2885	chlorophyll binding
CUC60_RS01860	COG0204	Acyl-transferase
CUC60_RS01875	COG2894	cell division
CUC60_RS01895	COG1280	lysine exporter protein (LysE YggA)
CUC60_RS01900	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CUC60_RS01900	COG1674	ftsk spoiiie
CUC60_RS01905	COG0492	ferredoxin-NADP+ reductase activity
CUC60_RS01910	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CUC60_RS01920	COG0456	acetyltransferase
CUC60_RS01965	COG1981	membrane
CUC60_RS01980	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CUC60_RS01980	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CUC60_RS02000	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS02010	COG0657	acetylesterase activity
CUC60_RS02020	COG0473	3-isopropylmalate dehydrogenase activity
CUC60_RS02025	COG0583	DNA-binding transcription factor activity
CUC60_RS02045	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUC60_RS02070	COG0564	pseudouridine synthase activity
CUC60_RS02080	COG0358	DNA primase activity
CUC60_RS02095	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CUC60_RS02125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CUC60_RS02155	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CUC60_RS02165	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CUC60_RS02165	COG0351	phosphomethylpyrimidine kinase
CUC60_RS02165	COG0352	thiamine-phosphate diphosphorylase activity
CUC60_RS02170	COG1652	LysM domain
CUC60_RS02195	COG1399	metal-binding, possibly nucleic acid-binding protein
CUC60_RS02200	COG3101	peptidyl-lysine hydroxylation
CUC60_RS02205	COG0009	L-threonylcarbamoyladenylate synthase
CUC60_RS02210	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CUC60_RS02215	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CUC60_RS02230	COG4106	trans-aconitate 2-methyltransferase activity
CUC60_RS02245	COG2226	methyltransferase
CUC60_RS02245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CUC60_RS02245	COG0596	Alpha beta hydrolase
CUC60_RS02250	COG1877	trehalose-phosphatase activity
CUC60_RS02255	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CUC60_RS02260	COG2223	nitrite transmembrane transporter activity
CUC60_RS02280	COG1196	nuclear chromosome segregation
CUC60_RS02290	COG0730	response to heat
CUC60_RS02305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CUC60_RS02315	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUC60_RS02375	COG0489	protein tyrosine kinase activity
CUC60_RS02385	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC60_RS02385	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC60_RS02415	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CUC60_RS02420	COG2081	HI0933 family
CUC60_RS02430	COG0668	transmembrane transport
CUC60_RS02450	COG0583	DNA-binding transcription factor activity
CUC60_RS02470	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CUC60_RS02475	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CUC60_RS02505	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CUC60_RS02545	COG0745	RESPONSE REGULATOR receiver
CUC60_RS02565	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CUC60_RS02645	COG4993	Dehydrogenase
CUC60_RS02665	COG0384	phenazine biosynthesis protein PhzF
CUC60_RS02695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_RS02710	COG0583	DNA-binding transcription factor activity
CUC60_RS02740	COG0583	DNA-binding transcription factor activity
CUC60_RS02760	COG0583	DNA-binding transcription factor activity
CUC60_RS02775	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CUC60_RS02780	COG2814	Major facilitator Superfamily
CUC60_RS02785	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS02790	COG0583	DNA-binding transcription factor activity
CUC60_RS02795	COG1063	alcohol dehydrogenase
CUC60_RS02825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CUC60_RS02830	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CUC60_RS02835	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUC60_RS02860	COG3667	copper resistance
CUC60_RS02865	COG2132	Multicopper oxidase
CUC60_RS02875	COG0561	phosphatase activity
CUC60_RS02880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CUC60_RS02905	COG1214	PFAM Peptidase M22, glycoprotease
CUC60_RS02955	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CUC60_RS02965	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CUC60_RS02970	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CUC60_RS02975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CUC60_RS03035	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CUC60_RS03045	COG1846	Transcriptional regulator
CUC60_RS03050	COG1764	response to oxidative stress
CUC60_RS03090	COG0037	tRNA processing
CUC60_RS03100	COG0248	Ppx GppA phosphatase
CUC60_RS03170	COG1238	metal cluster binding
CUC60_RS03175	COG0625	glutathione transferase activity
CUC60_RS03195	COG0318	PFAM AMP-dependent synthetase and ligase
CUC60_RS03200	COG3028	Belongs to the UPF0307 family
CUC60_RS03205	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUC60_RS03225	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CUC60_RS03230	COG0617	tRNA 3'-terminal CCA addition
CUC60_RS03235	COG1555	photosystem II stabilization
CUC60_RS03240	COG3956	TIGRFAM MazG family protein
CUC60_RS03250	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CUC60_RS03270	COG5002	protein histidine kinase activity
CUC60_RS03270	COG0784	Response regulator, receiver
CUC60_RS03270	COG2205	protein histidine kinase activity
CUC60_RS03275	COG1024	Enoyl-CoA hydratase
CUC60_RS03280	COG2084	Dehydrogenase
CUC60_RS03285	COG3622	Belongs to the hyi family
CUC60_RS03315	COG0697	spore germination
CUC60_RS03325	COG2814	Major facilitator Superfamily
CUC60_RS03330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CUC60_RS03340	COG0583	DNA-binding transcription factor activity
CUC60_RS03350	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CUC60_RS03365	COG0084	hydrolase, TatD family'
CUC60_RS03380	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CUC60_RS03415	COG0440	acetolactate synthase activity
CUC60_RS03420	COG0028	Belongs to the TPP enzyme family
CUC60_RS03445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_RS03450	COG1136	(ABC) transporter
CUC60_RS03450	COG0577	efflux transmembrane transporter activity
CUC60_RS03455	COG1538	Outer membrane efflux protein
CUC60_RS03470	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CUC60_RS03475	COG1162	GTPase activity
CUC60_RS03485	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CUC60_RS03505	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CUC60_RS03510	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS03550	COG2986	histidine ammonia-lyase
CUC60_RS03575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUC60_RS03620	COG1426	Protein conserved in bacteria
CUC60_RS03655	COG0793	Belongs to the peptidase S41A family
CUC60_RS03670	COG2267	carboxylic ester hydrolase activity
CUC60_RS03680	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS03685	COG3265	gluconokinase activity
CUC60_RS03705	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CUC60_RS03710	COG0280	phosphate acetyltransferase
CUC60_RS03710	COG0857	belongs to the CobB CobQ family
CUC60_RS03715	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CUC60_RS03715	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CUC60_RS03735	COG0740	serine-type endopeptidase activity
CUC60_RS03745	COG4774	siderophore transport
CUC60_RS03755	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CUC60_RS03765	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CUC60_RS03765	COG2813	Specifically methylates the guanine in position
CUC60_RS03865	COG0788	formyltetrahydrofolate deformylase activity
CUC60_RS03890	COG4651	solute:proton antiporter activity
CUC60_RS03890	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUC60_RS03910	COG0724	RNA recognition motif
CUC60_RS03915	COG0210	DNA helicase
CUC60_RS03940	COG1733	regulation of RNA biosynthetic process
CUC60_RS03950	COG2900	Belongs to the SlyX family
CUC60_RS03955	COG0488	(ABC) transporter
CUC60_RS03960	COG1280	lysine exporter protein (LysE YggA)
CUC60_RS03965	COG1560	Kdo2-lipid A biosynthetic process
CUC60_RS03975	COG1301	dicarboxylic acid transport
CUC60_RS04030	COG0473	3-isopropylmalate dehydrogenase activity
CUC60_RS04095	COG0583	DNA-binding transcription factor activity
CUC60_RS04105	COG0625	glutathione transferase activity
CUC60_RS04110	COG2378	regulation of single-species biofilm formation
CUC60_RS04115	COG0546	phosphoglycolate phosphatase activity
CUC60_RS04130	COG1530	ribonuclease E activity
CUC60_RS04135	COG0318	PFAM AMP-dependent synthetase and ligase
CUC60_RS04150	COG0583	DNA-binding transcription factor activity
CUC60_RS04160	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CUC60_RS04170	COG0534	Mate efflux family protein
CUC60_RS04185	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CUC60_RS04225	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CUC60_RS04230	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC60_RS04245	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CUC60_RS04255	COG0644	oxidoreductase
CUC60_RS04255	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CUC60_RS04260	COG0425	Belongs to the sulfur carrier protein TusA family
CUC60_RS04265	COG4535	Mg2 and Co2 transporter CorC
CUC60_RS04275	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CUC60_RS04295	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CUC60_RS04300	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUC60_RS04300	COG0475	glutathione-regulated potassium exporter activity
CUC60_RS04305	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CUC60_RS04315	COG0484	heat shock protein binding
CUC60_RS04320	COG0789	Transcriptional regulator
CUC60_RS04325	COG0598	Magnesium transport protein CorA
CUC60_RS04340	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CUC60_RS04345	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CUC60_RS04350	COG1074	ATP-dependent DNA helicase activity
CUC60_RS04355	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CUC60_RS04375	COG2226	methyltransferase
CUC60_RS04390	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_RS04395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CUC60_RS04410	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CUC60_RS04410	COG2111	Na H antiporter
CUC60_RS04415	COG1006	Multisubunit Na H antiporter MnhC subunit
CUC60_RS04420	COG0651	ATP synthesis coupled electron transport
CUC60_RS04425	COG1863	multisubunit Na H antiporter MnhE subunit
CUC60_RS04430	COG2212	antiporter activity
CUC60_RS04435	COG1320	monovalent cation:proton antiporter activity
CUC60_RS04450	COG0195	Participates in both transcription termination and antitermination
CUC60_RS04500	COG0237	dephospho-CoA kinase activity
CUC60_RS04510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUC60_RS04525	COG0497	DNA recombination
CUC60_RS04535	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CUC60_RS04565	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CUC60_RS04565	COG2169	Transcriptional regulator
CUC60_RS04570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CUC60_RS04640	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CUC60_RS04655	COG0326	Molecular chaperone. Has ATPase activity
CUC60_RS04670	COG2056	Na+-H+ antiporter family
CUC60_RS04675	COG0596	Alpha beta hydrolase
CUC60_RS04770	COG0546	phosphoglycolate phosphatase activity
CUC60_RS04775	COG1716	ATPase activity
CUC60_RS04820	COG0181	hydroxymethylbilane synthase activity
CUC60_RS04830	COG3275	phosphorelay sensor kinase activity
CUC60_RS04850	COG1538	Outer membrane efflux protein
CUC60_RS04855	COG0697	spore germination
CUC60_RS04880	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CUC60_RS04885	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CUC60_RS04890	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CUC60_RS04895	COG0772	Belongs to the SEDS family
CUC60_RS04920	COG4974	Belongs to the 'phage' integrase family
CUC60_RS04925	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CUC60_RS04935	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CUC60_RS04945	COG2197	response regulator
CUC60_RS04960	COG0793	Belongs to the peptidase S41A family
CUC60_RS05010	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUC60_RS05010	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CUC60_RS05020	COG0004	ammonium transporteR
CUC60_RS05025	COG0347	Belongs to the P(II) protein family
CUC60_RS05035	COG0606	chelatase, subunit chli
CUC60_RS05070	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC60_RS05090	COG1192	Involved in chromosome partitioning
CUC60_RS05275	COG0482	sulfurtransferase activity
CUC60_RS05375	COG1061	Type III restriction enzyme res subunit
CUC60_RS05395	COG0589	response to stress
CUC60_RS05440	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC60_RS05490	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CUC60_RS05525	COG0589	response to stress
CUC60_RS05555	COG0606	chelatase, subunit chli
CUC60_RS05560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_RS05570	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC60_RS05585	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CUC60_RS05600	COG0318	PFAM AMP-dependent synthetase and ligase
CUC60_RS05610	COG0477	Major facilitator Superfamily
CUC60_RS05615	COG2860	membrane
CUC60_RS05620	COG3012	SEC-C Motif Domain Protein
CUC60_RS05625	COG1253	flavin adenine dinucleotide binding
CUC60_RS05635	COG0477	Major facilitator Superfamily
CUC60_RS05645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CUC60_RS05680	COG0655	NAD(P)H dehydrogenase (quinone) activity
CUC60_RS05690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CUC60_RS05725	COG1309	transcriptional regulator
CUC60_RS05760	COG0758	DNA mediated transformation
CUC60_RS05770	COG0697	spore germination
CUC60_RS05775	COG1309	transcriptional regulator
CUC60_RS05790	COG0386	Belongs to the glutathione peroxidase family
CUC60_RS05860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CUC60_RS05865	COG1280	lysine exporter protein (LysE YggA)
CUC60_RS05870	COG2837	iron assimilation
CUC60_RS05875	COG0281	malic enzyme
CUC60_RS05920	COG0519	Catalyzes the synthesis of GMP from XMP
CUC60_RS05920	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CUC60_RS05930	COG2259	Doxx family
CUC60_RS05935	COG0586	Pfam SNARE associated Golgi protein
CUC60_RS05950	COG1192	Involved in chromosome partitioning
CUC60_RS05960	COG0271	Belongs to the BolA IbaG family
CUC60_RS05980	COG2267	carboxylic ester hydrolase activity
CUC60_RS06000	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CUC60_RS06000	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CUC60_RS06000	COG3321	synthase
CUC60_RS06000	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CUC60_RS06005	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS06015	COG2197	response regulator
CUC60_RS06025	COG3916	Acyl-homoserine-lactone synthase
CUC60_RS06035	COG1024	Enoyl-CoA hydratase
CUC60_RS06040	COG1024	Enoyl-CoA hydratase
CUC60_RS06045	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS06050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CUC60_RS06070	COG1113	amino acid transport
CUC60_RS06075	COG1113	amino acid transport
CUC60_RS06080	COG0251	oxidation-reduction process
CUC60_RS06120	COG0564	pseudouridine synthase activity
CUC60_RS06180	COG2801	Transposase and inactivated derivatives
CUC60_RS06220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CUC60_RS06235	COG1802	Transcriptional regulator
CUC60_RS06245	COG1448	Aminotransferase
CUC60_RS06250	COG0277	FAD linked oxidase domain protein
CUC60_RS06260	COG2186	Transcriptional regulator
CUC60_RS06270	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CUC60_RS06275	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUC60_RS06290	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CUC60_RS06305	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CUC60_RS06320	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CUC60_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS06365	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS06370	COG1083	cytidylyl-transferase
CUC60_RS06375	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CUC60_RS06385	COG2089	acid synthase
CUC60_RS06390	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
CUC60_RS06395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CUC60_RS06405	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CUC60_RS06435	COG0728	peptidoglycan biosynthetic process
CUC60_RS06440	COG3023	N-Acetylmuramoyl-L-alanine amidase
CUC60_RS06495	COG0546	phosphoglycolate phosphatase activity
CUC60_RS06500	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS06520	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC60_RS06525	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC60_RS06530	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC60_RS06535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC60_RS06540	COG1116	anion transmembrane transporter activity
CUC60_RS06545	COG1309	transcriptional regulator
CUC60_RS06550	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CUC60_RS06560	COG0196	riboflavin kinase activity
CUC60_RS06565	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CUC60_RS06575	COG1047	Peptidyl-prolyl cis-trans
CUC60_RS06620	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CUC60_RS06625	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CUC60_RS06630	COG0596	Alpha beta hydrolase
CUC60_RS06655	COG0488	(ABC) transporter
CUC60_RS06660	COG0586	Pfam SNARE associated Golgi protein
CUC60_RS06670	COG0187	DNA topoisomerase II activity
CUC60_RS06680	COG0592	DNA-directed DNA polymerase activity
CUC60_RS06705	COG0706	membrane insertase activity
CUC60_RS06720	COG1230	cation diffusion facilitator family transporter
CUC60_RS06725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CUC60_RS06750	COG0754	glutathionylspermidine amidase activity
CUC60_RS06760	COG0861	Integral membrane protein TerC family
CUC60_RS06765	COG0671	phosphoesterase, PA-phosphatase related
CUC60_RS06775	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CUC60_RS06795	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CUC60_RS06800	COG2951	lytic endotransglycosylase activity
CUC60_RS06850	COG0657	acetylesterase activity
CUC60_RS06855	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CUC60_RS06895	COG0733	neurotransmitter:sodium symporter activity
CUC60_RS06930	COG0583	DNA-binding transcription factor activity
CUC60_RS06935	COG2233	PERMEase
CUC60_RS06950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_RS06985	COG2814	Major facilitator Superfamily
CUC60_RS06990	COG0656	L-ascorbic acid biosynthetic process
CUC60_RS06995	COG0583	DNA-binding transcription factor activity
CUC60_RS07010	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_RS07015	COG1064	alcohol dehydrogenase
CUC60_RS07020	COG2818	Glycosylase
CUC60_RS07035	COG1194	a g-specific adenine glycosylase
CUC60_RS07055	COG2983	Belongs to the UPF0260 family
CUC60_RS07060	COG2133	pyrroloquinoline quinone binding
CUC60_RS07065	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CUC60_RS07070	COG2116	formate transmembrane transporter activity
CUC60_RS07090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC60_RS07095	COG1335	isochorismatase
CUC60_RS07100	COG0385	Bile acid
CUC60_RS07105	COG0534	Mate efflux family protein
CUC60_RS07110	COG1683	Conserved Protein
CUC60_RS07130	COG0625	glutathione transferase activity
CUC60_RS07140	COG1113	amino acid transport
CUC60_RS07150	COG0523	cobalamin synthesis protein
CUC60_RS07190	COG0010	Belongs to the arginase family
CUC60_RS07205	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CUC60_RS07225	COG0745	RESPONSE REGULATOR receiver
CUC60_RS07225	COG4191	Histidine kinase
CUC60_RS07225	COG2205	protein histidine kinase activity
CUC60_RS07260	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CUC60_RS07270	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CUC60_RS07275	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CUC60_RS07365	COG0534	Mate efflux family protein
CUC60_RS07370	COG0436	Aminotransferase
CUC60_RS07375	COG2733	membrane
CUC60_RS07390	COG2918	glutathione biosynthetic process
CUC60_RS07450	COG3150	esterase
CUC60_RS07460	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS07465	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CUC60_RS07475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_RS07485	COG2233	PERMEase
CUC60_RS07490	COG2351	hydroxyisourate hydrolase activity
CUC60_RS07525	COG3706	GGDEF domain
CUC60_RS07540	COG1393	Belongs to the ArsC family
CUC60_RS07545	COG0708	Exodeoxyribonuclease III
CUC60_RS07565	COG0189	ligase activity
CUC60_RS07585	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CUC60_RS07595	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CUC60_RS07610	COG4942	peptidase
CUC60_RS07620	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUC60_RS07630	COG2119	membrane
CUC60_RS07635	COG4774	siderophore transport
CUC60_RS07640	COG0426	domain, Protein
CUC60_RS07640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_RS07665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CUC60_RS07685	COG1902	pentaerythritol trinitrate reductase activity
CUC60_RS07695	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CUC60_RS07700	COG0668	transmembrane transport
CUC60_RS07710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CUC60_RS07715	COG1335	isochorismatase
CUC60_RS07720	COG1522	sequence-specific DNA binding
CUC60_RS07725	COG3328	transposase activity
CUC60_RS07750	COG2205	protein histidine kinase activity
CUC60_RS07750	COG0784	Response regulator, receiver
CUC60_RS07750	COG2198	Histidine kinase
CUC60_RS07755	COG3162	membrane
CUC60_RS07760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC60_RS07770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_RS07790	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CUC60_RS07795	COG1309	transcriptional regulator
CUC60_RS07815	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CUC60_RS07815	COG0352	thiamine-phosphate diphosphorylase activity
CUC60_RS07815	COG0351	phosphomethylpyrimidine kinase
CUC60_RS07825	COG2814	Major facilitator Superfamily
CUC60_RS07840	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CUC60_RS07850	COG1113	amino acid transport
CUC60_RS07860	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CUC60_RS07865	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS07875	COG1335	isochorismatase
CUC60_RS07905	COG2814	Major facilitator Superfamily
CUC60_RS07910	COG0583	DNA-binding transcription factor activity
CUC60_RS07930	COG0667	Aldo Keto reductase
CUC60_RS07965	COG1733	regulation of RNA biosynthetic process
CUC60_RS07975	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUC60_RS08040	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CUC60_RS08055	COG2329	Antibiotic biosynthesis monooxygenase
CUC60_RS08085	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CUC60_RS08115	COG0427	acetyl-CoA hydrolase
CUC60_RS08140	COG0659	secondary active sulfate transmembrane transporter activity
CUC60_RS08145	COG4221	oxidoreductase activity
CUC60_RS08150	COG2873	o-acetylhomoserine
CUC60_RS08155	COG0488	(ABC) transporter
CUC60_RS08240	COG0833	amino acid
CUC60_RS08285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CUC60_RS08290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CUC60_RS08305	COG2226	methyltransferase
CUC60_RS08355	COG0067	glutamate synthase
CUC60_RS08355	COG0069	glutamate synthase activity
CUC60_RS08355	COG0070	glutamate synthase
CUC60_RS08360	COG0493	'glutamate synthase
CUC60_RS08370	COG1704	LemA family
CUC60_RS08375	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CUC60_RS08395	COG3307	-O-antigen
CUC60_RS08420	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CUC60_RS08435	COG0194	GDP metabolic process
CUC60_RS08485	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CUC60_RS08505	COG5380	lipid catabolic process
CUC60_RS08510	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CUC60_RS08535	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CUC60_RS08540	COG0277	FAD linked oxidase domain protein
CUC60_RS08550	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CUC60_RS08555	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUC60_RS08570	COG1289	transmembrane transporter activity
CUC60_RS08580	COG0628	permease
CUC60_RS08585	COG1192	Involved in chromosome partitioning
CUC60_RS08615	COG0833	amino acid
CUC60_RS08620	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CUC60_RS08635	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS08680	COG0583	DNA-binding transcription factor activity
CUC60_RS08725	COG0517	IMP dehydrogenase activity
CUC60_RS08730	COG1983	PspC domain protein
CUC60_RS08740	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS08760	COG0408	coproporphyrinogen oxidase activity
CUC60_RS08780	COG0513	Belongs to the DEAD box helicase family
CUC60_RS08790	COG1127	ABC transporter
CUC60_RS08795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CUC60_RS08805	COG2854	intermembrane phospholipid transfer
CUC60_RS08815	COG0598	Magnesium transport protein CorA
CUC60_RS08825	COG0494	nUDIX hydrolase
CUC60_RS08830	COG1040	competence protein
CUC60_RS08835	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CUC60_RS08855	COG1946	Acyl-CoA thioesterase
CUC60_RS08860	COG1301	dicarboxylic acid transport
CUC60_RS08880	COG1959	2 iron, 2 sulfur cluster binding
CUC60_RS08885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUC60_RS08885	COG1017	nitric oxide dioxygenase activity
CUC60_RS08890	COG0433	COG0433 Predicted ATPase
CUC60_RS08895	COG0626	cystathionine gamma-synthase activity
CUC60_RS09050	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS09055	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CUC60_RS09085	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CUC60_RS09090	COG0339	signal peptide processing
CUC60_RS09095	COG0557	exoribonuclease II activity
CUC60_RS09140	COG0179	Fumarylacetoacetate (FAA) hydrolase
CUC60_RS09145	COG2169	Transcriptional regulator
CUC60_RS09150	COG0697	spore germination
CUC60_RS09155	COG1295	ribonuclease BN
CUC60_RS09190	COG1702	phosphate starvation-inducible protein PhoH
CUC60_RS09200	COG0741	lytic transglycosylase activity
CUC60_RS09200	COG0739	heme binding
CUC60_RS09200	COG1196	nuclear chromosome segregation
CUC60_RS09230	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CUC60_RS09235	COG1183	phosphatidylcholine synthase activity
CUC60_RS09280	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS09285	COG1309	transcriptional regulator
CUC60_RS09300	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CUC60_RS09305	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS09325	COG2969	positive regulation of protein catabolic process
CUC60_RS09335	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CUC60_RS09350	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CUC60_RS09355	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CUC60_RS09375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CUC60_RS09385	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUC60_RS09390	COG1408	metallophosphoesterase
CUC60_RS09400	COG2199	diguanylate cyclase activity
CUC60_RS09460	COG1607	acyl-coa hydrolase
CUC60_RS09490	COG2350	Protein conserved in bacteria
CUC60_RS09500	COG0613	PHP domain protein
CUC60_RS09505	COG3781	membrane
CUC60_RS09515	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CUC60_RS09520	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CUC60_RS09530	COG1862	Preprotein translocase
CUC60_RS09560	COG2205	protein histidine kinase activity
CUC60_RS09565	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CUC60_RS09585	COG0726	polysaccharide deacetylase
CUC60_RS09590	COG0463	Glycosyl transferase, family 2
CUC60_RS09595	COG0438	transferase activity, transferring glycosyl groups
CUC60_RS09660	COG0625	glutathione transferase activity
CUC60_RS09665	COG0583	DNA-binding transcription factor activity
CUC60_RS09670	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS09675	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS09685	COG2205	protein histidine kinase activity
CUC60_RS09690	COG0745	RESPONSE REGULATOR receiver
CUC60_RS09695	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CUC60_RS09715	COG2096	Adenosyltransferase
CUC60_RS09765	COG0285	dihydrofolate synthase activity
CUC60_RS09785	COG0450	alkyl hydroperoxide reductase
CUC60_RS09800	COG0477	Major facilitator Superfamily
CUC60_RS09805	COG1272	protein, Hemolysin III
CUC60_RS09835	COG0183	Belongs to the thiolase family
CUC60_RS09840	COG2207	Transcriptional regulator
CUC60_RS09860	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_RS09880	COG0183	Belongs to the thiolase family
CUC60_RS09890	COG2885	chlorophyll binding
CUC60_RS09890	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CUC60_RS09900	COG1690	Belongs to the RtcB family
CUC60_RS09905	COG0833	amino acid
CUC60_RS09915	COG2233	PERMEase
CUC60_RS09920	COG1217	gtp-binding protein TYPA
CUC60_RS09945	COG2094	Belongs to the DNA glycosylase MPG family
CUC60_RS09950	COG4772	TonB-dependent receptor
CUC60_RS09965	COG1902	pentaerythritol trinitrate reductase activity
CUC60_RS09970	COG0679	Auxin Efflux Carrier
CUC60_RS09980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CUC60_RS09985	COG0354	folic acid binding
CUC60_RS09995	COG3189	MarR family transcriptional regulator
CUC60_RS10000	COG2824	Alkylphosphonate utilization operon protein PhnA
CUC60_RS10005	COG3422	double-strand break repair
CUC60_RS10045	COG0840	transmembrane signaling receptor activity
CUC60_RS10065	COG5510	response to toxic substance
CUC60_RS10075	COG2832	Protein of unknown function (DUF454)
CUC60_RS10080	COG1376	ErfK ybiS ycfS ynhG family protein
CUC60_RS10120	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CUC60_RS10130	COG1289	transmembrane transporter activity
CUC60_RS10135	COG2814	Major facilitator Superfamily
CUC60_RS10155	COG1115	amino acid carrier protein
CUC60_RS10165	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CUC60_RS10170	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CUC60_RS10200	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CUC60_RS10210	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CUC60_RS10215	COG1077	Cell shape determining protein MreB Mrl
CUC60_RS10220	COG1792	Involved in formation and maintenance of cell shape
CUC60_RS10225	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CUC60_RS10230	COG0424	maF-like protein
CUC60_RS10235	COG1530	ribonuclease E activity
CUC60_RS10245	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CUC60_RS10255	COG0560	Phosphoserine phosphatase
CUC60_RS10265	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUC60_RS10290	COG2207	Transcriptional regulator
CUC60_RS10310	COG1113	amino acid transport
CUC60_RS10315	COG2828	Protein conserved in bacteria
CUC60_RS10320	COG0142	geranyltranstransferase activity
CUC60_RS10325	COG2315	Protein conserved in bacteria
CUC60_RS10340	COG1752	Esterase of the alpha-beta hydrolase superfamily
CUC60_RS10365	COG2194	sulfuric ester hydrolase activity
CUC60_RS10370	COG0745	RESPONSE REGULATOR receiver
CUC60_RS10375	COG0642	Histidine kinase
CUC60_RS10385	COG0004	ammonium transporteR
CUC60_RS10395	COG0583	DNA-binding transcription factor activity
CUC60_RS10415	COG0525	valine-tRNA ligase activity
CUC60_RS10425	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS10435	COG0393	Putative heavy-metal-binding
CUC60_RS10440	COG0393	Putative heavy-metal-binding
CUC60_RS10445	COG1538	Outer membrane efflux protein
CUC60_RS10455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_RS10460	COG0671	phosphoesterase, PA-phosphatase related
CUC60_RS10490	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CUC60_RS10505	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CUC60_RS10505	COG1648	precorrin-2 dehydrogenase activity
CUC60_RS10510	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CUC60_RS10515	COG1733	regulation of RNA biosynthetic process
CUC60_RS10525	COG0531	amino acid
CUC60_RS10540	COG0321	lipoyl(octanoyl) transferase activity
CUC60_RS10545	COG2921	Belongs to the UPF0250 family
CUC60_RS10585	COG2009	succinate dehydrogenase
CUC60_RS10590	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CUC60_RS10595	COG1053	succinate dehydrogenase
CUC60_RS10600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CUC60_RS10625	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC60_RS10645	COG2354	Protein conserved in bacteria
CUC60_RS10650	COG2321	neutral zinc metallopeptidase
CUC60_RS10700	COG0589	response to stress
CUC60_RS10720	COG0505	Belongs to the CarA family
CUC60_RS10745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CUC60_RS10750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CUC60_RS10800	COG0477	Major facilitator Superfamily
CUC60_RS10805	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CUC60_RS10820	COG1597	lipid kinase activity
CUC60_RS10825	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CUC60_RS10855	COG0584	glycerophosphoryl diester phosphodiesterase
CUC60_RS10875	COG0741	lytic transglycosylase activity
CUC60_RS10900	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CUC60_RS10915	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CUC60_RS10935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_RS10965	COG4584	PFAM Integrase catalytic
CUC60_RS10965	COG2390	Transcriptional regulator
CUC60_RS10970	COG1484	DNA-dependent DNA replication
CUC60_RS11000	COG0778	Nitroreductase
CUC60_RS11015	COG1929	Belongs to the glycerate kinase type-1 family
CUC60_RS11020	COG0243	molybdopterin cofactor binding
CUC60_RS11025	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CUC60_RS11030	COG3339	Conserved Protein
CUC60_RS11040	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CUC60_RS11055	COG1113	amino acid transport
CUC60_RS11075	COG1280	lysine exporter protein (LysE YggA)
CUC60_RS11080	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CUC60_RS11110	COG0463	Glycosyl transferase, family 2
CUC60_RS11130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_RS11160	COG4591	ABC-type transport system involved in lipoprotein release permease component
CUC60_RS11165	COG1136	(ABC) transporter
CUC60_RS11170	COG2333	competence protein COMEC
CUC60_RS11170	COG0658	competence protein
CUC60_RS11180	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CUC60_RS11180	COG0616	signal peptide processing
CUC60_RS11185	COG0596	Alpha beta hydrolase
CUC60_RS11190	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CUC60_RS11200	COG0628	permease
CUC60_RS11235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CUC60_RS11255	COG0823	Involved in the tonB-independent uptake of proteins
CUC60_RS11275	COG0824	Thioesterase
CUC60_RS11280	COG1473	amidohydrolase
CUC60_RS11300	COG0047	phosphoribosylformylglycinamidine synthase activity
CUC60_RS11300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CUC60_RS11305	COG2814	Major facilitator Superfamily
CUC60_RS11315	COG1024	Enoyl-CoA hydratase
CUC60_RS11320	COG1051	belongs to the nudix hydrolase family
CUC60_RS11320	COG1056	cytidyltransferase-related domain
CUC60_RS11330	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CUC60_RS11345	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CUC60_RS11360	COG4625	pathogenesis
CUC60_RS11365	COG0583	DNA-binding transcription factor activity
CUC60_RS11370	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CUC60_RS11375	COG4208	sulfate ABC transporter
CUC60_RS11380	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CUC60_RS11390	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CUC60_RS11395	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CUC60_RS11400	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CUC60_RS11420	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC60_RS11435	COG0681	Belongs to the peptidase S26 family
CUC60_RS11450	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CUC60_RS11460	COG1381	Involved in DNA repair and RecF pathway recombination
CUC60_RS11465	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CUC60_RS11475	COG4221	oxidoreductase activity
CUC60_RS11505	COG0436	Aminotransferase
CUC60_RS11525	COG0556	nucleotide-excision repair
CUC60_RS11610	COG1215	transferase activity, transferring glycosyl groups
CUC60_RS11625	COG0415	Belongs to the DNA photolyase family
CUC60_RS11635	COG1252	NADH dehydrogenase
CUC60_RS11655	COG1187	pseudouridine synthase activity
CUC60_RS11685	COG0583	DNA-binding transcription factor activity
CUC60_RS11725	COG0352	thiamine-phosphate diphosphorylase activity
CUC60_RS11760	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUC60_RS11775	COG1309	transcriptional regulator
CUC60_RS11785	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CUC60_RS11800	COG1522	sequence-specific DNA binding
CUC60_RS11805	COG3961	Belongs to the TPP enzyme family
CUC60_RS11810	COG1113	amino acid transport
CUC60_RS11815	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CUC60_RS11820	COG0573	inorganic phosphate transmembrane transporter activity
CUC60_RS11830	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CUC60_RS11835	COG0616	signal peptide processing
CUC60_RS11870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CUC60_RS11875	COG1686	Belongs to the peptidase S11 family
CUC60_RS11900	COG0583	DNA-binding transcription factor activity
CUC60_RS11905	COG1067	ATP-dependent peptidase activity
CUC60_RS11950	COG1966	Carbon starvation protein
CUC60_RS11955	COG2879	small protein
CUC60_RS11990	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CUC60_RS11990	COG2508	Transcriptional regulator
CUC60_RS12010	COG1113	amino acid transport
CUC60_RS12015	COG0583	DNA-binding transcription factor activity
CUC60_RS12020	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_RS12025	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CUC60_RS12035	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS12040	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_RS12045	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CUC60_RS12045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUC60_RS12080	COG2814	Major facilitator Superfamily
CUC60_RS12085	COG4948	Mandelate Racemase Muconate Lactonizing
CUC60_RS12095	COG1309	transcriptional regulator
CUC60_RS12115	COG1741	Belongs to the pirin family
CUC60_RS12125	COG2964	Protein conserved in bacteria
CUC60_RS12140	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CUC60_RS12145	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUC60_RS12150	COG4605	iron ion homeostasis
CUC60_RS12155	COG4604	ABC transporter, ATP-binding protein
CUC60_RS12160	COG4607	ABC-type enterochelin transport system periplasmic component
CUC60_RS12175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CUC60_RS12180	COG1021	2,3-dihydroxybenzoate-AMP ligase
CUC60_RS12185	COG1535	isochorismatase
CUC60_RS12185	COG3433	isochorismatase activity
CUC60_RS12200	COG1132	(ABC) transporter
CUC60_RS12205	COG1132	(ABC) transporter
CUC60_RS12210	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CUC60_RS12220	COG1169	isochorismate synthase
CUC60_RS12235	COG3739	integral membrane protein
CUC60_RS12260	COG0302	gtp cyclohydrolase
CUC60_RS12305	COG0512	Glutamine amidotransferase of anthranilate synthase
CUC60_RS12480	COG5410	chromosome segregation
CUC60_RS12635	COG0582	viral genome integration into host DNA
CUC60_RS12650	COG0174	glutamine synthetase
CUC60_RS12695	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CUC60_RS12705	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CUC60_RS12725	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CUC60_RS12730	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CUC60_RS12735	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CUC60_RS12750	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS12755	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CUC60_RS12760	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC60_RS12770	COG2223	nitrite transmembrane transporter activity
CUC60_RS12780	COG0024	Methionine aminopeptidase
CUC60_RS12785	COG0052	Belongs to the universal ribosomal protein uS2 family
CUC60_RS12800	COG2207	Transcriptional regulator
CUC60_RS12825	COG2951	lytic endotransglycosylase activity
CUC60_RS12830	COG0772	Belongs to the SEDS family
CUC60_RS12845	COG0842	Transport permease protein
CUC60_RS12850	COG1131	(ABC) transporter
CUC60_RS12895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_RS12910	COG4215	(ABC) transporter
CUC60_RS12915	COG4160	amino acid transport
CUC60_RS12930	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CUC60_RS12935	COG0826	peptidase U32
CUC60_RS12940	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_RS12955	COG1720	tRNA m6t6A37 methyltransferase activity
CUC60_RS12965	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CUC60_RS12980	COG0642	Histidine kinase
CUC60_RS12990	COG0494	nUDIX hydrolase
CUC60_RS13005	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CUC60_RS13010	COG3139	Protein of unknown function (DUF1315)
CUC60_RS13015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CUC60_RS13025	COG1301	dicarboxylic acid transport
CUC60_RS13030	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS13035	COG2819	hydrolase of the alpha beta superfamily
CUC60_RS13045	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CUC60_RS13055	COG2195	Cleaves the N-terminal amino acid of tripeptides
CUC60_RS13060	COG1234	tRNA 3'-trailer cleavage
CUC60_RS13090	COG2363	Small membrane protein
CUC60_RS13110	COG0513	Belongs to the DEAD box helicase family
CUC60_RS13120	COG0778	Nitroreductase
CUC60_RS13150	COG1286	toxin biosynthetic process
CUC60_RS13175	COG4783	chaperone-mediated protein folding
CUC60_RS13180	COG1610	YqeY-like protein
CUC60_RS13280	COG3111	PFAM Bacterial OB fold (BOF) protein
CUC60_RS13305	COG3243	poly(R)-hydroxyalkanoic acid synthase
CUC60_RS13310	COG0786	glutamate:sodium symporter activity
CUC60_RS13320	COG2186	Transcriptional regulator
CUC60_RS13370	COG0477	Major facilitator Superfamily
CUC60_RS13400	COG2985	domain, Protein
CUC60_RS13410	COG2995	paraquat-inducible protein a
CUC60_RS13415	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CUC60_RS13415	COG3008	intermembrane lipid transfer
CUC60_RS13425	COG1794	racemase activity, acting on amino acids and derivatives
CUC60_RS13520	COG1113	amino acid transport
CUC60_RS13530	COG0531	amino acid
CUC60_RS13550	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS13570	COG1113	amino acid transport
CUC60_RS13600	COG0300	oxidoreductase activity
CUC60_RS13610	COG1309	transcriptional regulator
CUC60_RS13615	COG1741	Belongs to the pirin family
CUC60_RS13630	COG2072	flavoprotein involved in K transport
CUC60_RS13640	COG2252	PERMEase
CUC60_RS13645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CUC60_RS13650	COG3038	cytochrome b561
CUC60_RS13660	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CUC60_RS13670	COG0527	aspartate kinase activity
CUC60_RS13680	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CUC60_RS13690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CUC60_RS13705	COG0667	Aldo Keto reductase
CUC60_RS13720	COG1765	OsmC-like protein
CUC60_RS13735	COG0542	response to heat
CUC60_RS13770	COG2885	chlorophyll binding
CUC60_RS13780	COG0625	glutathione transferase activity
CUC60_RS13785	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CUC60_RS13805	COG3634	alkyl hydroperoxide reductase activity
CUC60_RS13820	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CUC60_RS13830	COG0450	alkyl hydroperoxide reductase
CUC60_RS13835	COG1643	Atp-dependent helicase
CUC60_RS13855	COG3135	benzoate transporter
CUC60_RS13860	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS13865	COG0633	Ferredoxin
CUC60_RS13865	COG0543	2 iron, 2 sulfur cluster binding
CUC60_RS13870	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CUC60_RS13875	COG4638	Rieske (2fe-2S)
CUC60_RS13880	COG0583	DNA-binding transcription factor activity
CUC60_RS13935	COG1570	exodeoxyribonuclease VII activity
CUC60_RS13970	COG1280	lysine exporter protein (LysE YggA)
CUC60_RS13975	COG1278	Cold shock
CUC60_RS14015	COG2814	Major facilitator Superfamily
CUC60_RS14055	COG0517	IMP dehydrogenase activity
CUC60_RS14055	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CUC60_RS14060	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CUC60_RS14070	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CUC60_RS14075	COG1137	ATPase activity
CUC60_RS14080	COG1538	Outer membrane efflux protein
CUC60_RS14110	COG4122	O-methyltransferase activity
CUC60_RS14120	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CUC60_RS14135	COG1522	sequence-specific DNA binding
CUC60_RS14140	COG5006	permease, DMT superfamily
CUC60_RS14150	COG1560	Kdo2-lipid A biosynthetic process
CUC60_RS14165	COG2814	Major facilitator Superfamily
CUC60_RS14185	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUC60_RS14240	COG0583	DNA-binding transcription factor activity
CUC60_RS14245	COG1914	H( )-stimulated, divalent metal cation uptake system
CUC60_RS14265	COG4770	biotin carboxylase activity
CUC60_RS14270	COG0038	chloride channel
CUC60_RS14290	COG1309	transcriptional regulator
CUC60_RS14300	COG1063	alcohol dehydrogenase
CUC60_RS14315	COG0439	Biotin carboxylase
CUC60_RS14320	COG2249	NAD(P)H dehydrogenase (quinone) activity
CUC60_RS14340	COG0864	Transcriptional regulator
CUC60_RS14350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC60_RS14355	COG1116	anion transmembrane transporter activity
CUC60_RS14475	COG0590	tRNA wobble adenosine to inosine editing
CUC60_RS14480	COG2807	transmembrane transport
CUC60_RS14495	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CUC60_RS14510	COG0789	Transcriptional regulator
CUC60_RS14525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CUC60_RS14545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUC60_RS14555	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_RS14570	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS14575	COG0531	amino acid
CUC60_RS14580	COG1760	l-serine dehydratase
CUC60_RS14585	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS14585	COG2030	dehydratase
CUC60_RS14590	COG3396	Phenylacetate-CoA oxygenase
CUC60_RS14595	COG3460	Phenylacetate-CoA oxygenase
CUC60_RS14600	COG3396	Phenylacetate-CoA oxygenase
CUC60_RS14605	COG2151	metal-sulfur cluster biosynthetic enzyme
CUC60_RS14610	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUC60_RS14615	COG1024	Enoyl-CoA hydratase
CUC60_RS14620	COG1024	Enoyl-CoA hydratase
CUC60_RS14625	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUC60_RS14630	COG0183	Belongs to the thiolase family
CUC60_RS14635	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CUC60_RS14640	COG3327	negative regulation of DNA-templated transcription, initiation
CUC60_RS14650	COG2050	protein possibly involved in aromatic compounds catabolism
CUC60_RS14690	COG0753	catalase activity
CUC60_RS14695	COG3038	cytochrome b561
CUC60_RS14715	COG2267	carboxylic ester hydrolase activity
CUC60_RS14720	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_RS14725	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC60_RS14730	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS14740	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CUC60_RS14750	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS14755	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUC60_RS14760	COG0583	DNA-binding transcription factor activity
CUC60_RS14770	COG1414	Transcriptional regulator
CUC60_RS14775	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_RS14785	COG1840	ABC-type Fe3 transport system, periplasmic component
CUC60_RS14790	COG3842	ATPase activity
CUC60_RS14805	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CUC60_RS14810	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CUC60_RS14815	COG2814	Major facilitator Superfamily
CUC60_RS14820	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS14835	COG1024	Enoyl-CoA hydratase
CUC60_RS14845	COG2814	Major facilitator Superfamily
CUC60_RS14855	COG0183	Belongs to the thiolase family
CUC60_RS14860	COG1250	3-hydroxyacyl-CoA dehydrogenase
CUC60_RS14865	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS14870	COG1024	Enoyl-CoA hydratase
CUC60_RS14875	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS14880	COG2814	Major facilitator Superfamily
CUC60_RS14885	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CUC60_RS14890	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CUC60_RS14900	COG2814	Major facilitator Superfamily
CUC60_RS14910	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS14925	COG0583	DNA-binding transcription factor activity
CUC60_RS14935	COG4770	biotin carboxylase activity
CUC60_RS14940	COG1024	Enoyl-CoA hydratase
CUC60_RS14945	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CUC60_RS14950	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS14955	COG1309	transcriptional regulator
CUC60_RS14960	COG0318	PFAM AMP-dependent synthetase and ligase
CUC60_RS14980	COG0583	DNA-binding transcription factor activity
CUC60_RS15025	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS15045	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CUC60_RS15065	COG0784	Response regulator, receiver
CUC60_RS15065	COG2205	protein histidine kinase activity
CUC60_RS15085	COG0765	amino acid transport
CUC60_RS15090	COG0765	amino acid transport
CUC60_RS15095	COG1126	abc transporter atp-binding protein
CUC60_RS15100	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC60_RS15105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CUC60_RS15120	COG1280	lysine exporter protein (LysE YggA)
CUC60_RS15125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CUC60_RS15130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUC60_RS15135	COG1045	serine acetyltransferase
CUC60_RS15150	COG0583	DNA-binding transcription factor activity
CUC60_RS15155	COG0625	glutathione transferase activity
CUC60_RS15160	COG0625	glutathione transferase activity
CUC60_RS15165	COG0583	DNA-binding transcription factor activity
CUC60_RS15175	COG1346	cytolysis
CUC60_RS15195	COG2814	Major facilitator Superfamily
CUC60_RS15205	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CUC60_RS15210	COG3052	prosthetic group binding
CUC60_RS15230	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CUC60_RS15250	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_RS15260	COG1294	oxidase, subunit
CUC60_RS15265	COG1271	oxidase subunit
CUC60_RS15290	COG0477	Major facilitator Superfamily
CUC60_RS15300	COG4521	taurine ABC transporter
CUC60_RS15305	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
CUC60_RS15310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC60_RS15315	COG2175	clavaminate synthase activity
CUC60_RS15325	COG1953	Uracil, thiamine, allantoin
CUC60_RS15335	COG0583	DNA-binding transcription factor activity
CUC60_RS15345	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CUC60_RS15360	COG0640	Transcriptional regulator
CUC60_RS15365	COG0798	PFAM Bile acid sodium symporter
CUC60_RS15370	COG0583	DNA-binding transcription factor activity
CUC60_RS15385	COG3634	alkyl hydroperoxide reductase activity
CUC60_RS15425	COG0436	Aminotransferase
CUC60_RS15435	COG0386	Belongs to the glutathione peroxidase family
CUC60_RS15475	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CUC60_RS15500	COG0012	GTP binding
CUC60_RS15505	COG2011	ABC-type metal ion transport system permease component
CUC60_RS15510	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CUC60_RS15520	COG1464	Belongs to the NlpA lipoprotein family
CUC60_RS15550	COG0765	amino acid transport
CUC60_RS15555	COG0765	amino acid transport
CUC60_RS15560	COG1126	abc transporter atp-binding protein
CUC60_RS15570	COG1522	sequence-specific DNA binding
CUC60_RS15585	COG1309	transcriptional regulator
CUC60_RS15605	COG0583	DNA-binding transcription factor activity
CUC60_RS15615	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CUC60_RS15625	COG0697	spore germination
CUC60_RS15655	COG3121	Chaperone
CUC60_RS15660	COG3539	Fimbrial protein
CUC60_RS15685	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CUC60_RS15685	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CUC60_RS15730	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CUC60_RS15740	COG2353	YceI-like domain
CUC60_RS15750	COG3698	Phosphodiester glycosidase
CUC60_RS15765	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CUC60_RS15780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CUC60_RS15785	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CUC60_RS15805	COG1132	(ABC) transporter
CUC60_RS15810	COG3122	Protein conserved in bacteria
CUC60_RS15815	COG3619	membrane
CUC60_RS15825	COG0640	Transcriptional regulator
CUC60_RS15835	COG2850	peptidyl-arginine hydroxylation
CUC60_RS15840	COG0424	maF-like protein
CUC60_RS15860	COG0191	fructose-bisphosphate aldolase activity
CUC60_RS15865	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUC60_RS15880	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CUC60_RS15890	COG1192	Involved in chromosome partitioning
CUC60_RS15895	COG1475	DNA binding
CUC60_RS15900	COG0811	peptide transport
CUC60_RS15910	COG1132	(ABC) transporter
CUC60_RS15915	COG1663	tetraacyldisaccharide 4'-kinase activity
CUC60_RS15935	COG0084	hydrolase, TatD family'
CUC60_RS16000	COG0776	regulation of translation
CUC60_RS16030	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CUC60_RS16325	COG0741	lytic transglycosylase activity
CUC60_RS16325	COG0739	heme binding
CUC60_RS16325	COG1196	nuclear chromosome segregation
CUC60_RS16405	COG0006	proline dipeptidase activity
CUC60_RS16410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_RS16415	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CUC60_RS16435	COG1279	arginine transmembrane transporter activity
CUC60_RS16440	COG0583	DNA-binding transcription factor activity
CUC60_RS16480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUC60_RS16485	COG1388	LysM domain
CUC60_RS16485	COG0741	lytic transglycosylase activity
CUC60_RS16485	COG0741	lytic transglycosylase activity
CUC60_RS16485	COG1388	LysM domain
CUC60_RS16495	COG4174	ABC transporter (Permease)
CUC60_RS16500	COG4239	(ABC) transporter, permease
CUC60_RS16505	COG4172	Belongs to the ABC transporter superfamily
CUC60_RS16535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CUC60_RS16560	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_RS16560	COG1902	pentaerythritol trinitrate reductase activity
CUC60_RS16575	COG4269	membrane
CUC60_RS16675	COG0482	sulfurtransferase activity
CUC60_RS16730	COG1301	dicarboxylic acid transport
CUC60_RS16740	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC60_RS16745	COG2011	ABC-type metal ion transport system permease component
CUC60_RS16750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CUC60_RS16755	COG1464	Belongs to the NlpA lipoprotein family
CUC60_RS16760	COG0151	Belongs to the GarS family
CUC60_RS16765	COG0138	bifunctional purine biosynthesis protein purh
CUC60_RS16770	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CUC60_RS16810	COG1305	Transglutaminase-like
CUC60_RS16820	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CUC60_RS16825	COG0305	Participates in initiation and elongation during chromosome replication
CUC60_RS16850	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CUC60_RS16860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CUC60_RS16865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CUC60_RS16890	COG0726	polysaccharide deacetylase
CUC60_RS16890	COG1649	PFAM Uncharacterised BCR, COG1649
CUC60_RS16895	COG1215	transferase activity, transferring glycosyl groups
CUC60_RS16900	COG3658	cytochrome
CUC60_RS16910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CUC60_RS16930	COG0583	DNA-binding transcription factor activity
CUC60_RS16950	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC60_RS16955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC60_RS16970	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS16975	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CUC60_RS16980	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_RS17005	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CUC60_RS17010	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CUC60_RS17020	COG2205	protein histidine kinase activity
CUC60_RS17025	COG0745	RESPONSE REGULATOR receiver
CUC60_RS17030	COG0174	glutamine synthetase
CUC60_RS17050	COG0729	surface antigen
CUC60_RS17080	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CUC60_RS17085	COG2814	Major facilitator Superfamily
CUC60_RS17100	COG0583	DNA-binding transcription factor activity
CUC60_RS17115	COG1187	pseudouridine synthase activity
CUC60_RS17135	COG0802	atpase or kinase
CUC60_RS17140	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CUC60_RS17150	COG1923	regulation of RNA biosynthetic process
CUC60_RS17155	COG0697	spore germination
CUC60_RS17170	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUC60_RS17180	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CUC60_RS17185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CUC60_RS17185	COG0519	Catalyzes the synthesis of GMP from XMP
CUC60_RS17190	COG4302	ethanolamine ammonia-lyase activity
CUC60_RS17200	COG0531	amino acid
CUC60_RS17220	COG1454	alcohol dehydrogenase
CUC60_RS17225	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CUC60_RS17235	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CUC60_RS17255	COG0308	aminopeptidase N
CUC60_RS17265	COG4221	oxidoreductase activity
CUC60_RS17275	COG1605	Chorismate mutase
CUC60_RS17295	COG1309	transcriptional regulator
CUC60_RS17305	COG0668	transmembrane transport
CUC60_RS17340	COG4773	Receptor
CUC60_RS17360	COG0488	(ABC) transporter
CUC60_RS17365	COG0589	response to stress
CUC60_RS17380	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CUC60_RS17390	COG3135	benzoate transporter
CUC60_RS17395	COG1522	sequence-specific DNA binding
CUC60_RS17405	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CUC60_RS17410	COG0583	DNA-binding transcription factor activity
CUC60_RS17420	COG0183	Belongs to the thiolase family
CUC60_RS17430	COG2030	dehydratase
CUC60_RS17435	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CUC60_RS17450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CUC60_RS17460	COG0824	Thioesterase
CUC60_RS17465	COG1454	alcohol dehydrogenase
CUC60_RS17495	COG0069	glutamate synthase activity
CUC60_RS17665	COG5410	chromosome segregation
CUC60_RS17790	COG0739	heme binding
CUC60_RS17855	COG2194	sulfuric ester hydrolase activity
CUC60_RS17860	COG2814	Major facilitator Superfamily
CUC60_RS17875	COG0511	ligase activity, forming carbon-carbon bonds
CUC60_RS17895	COG1116	anion transmembrane transporter activity
CUC60_RS17895	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CUC60_RS17900	COG0745	RESPONSE REGULATOR receiver
CUC60_RS17910	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_RS17910	COG2146	nitrite reductase [NAD(P)H] activity
CUC60_RS17915	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CUC60_RS17920	COG0243	molybdopterin cofactor binding
CUC60_RS17930	COG0243	molybdopterin cofactor binding
CUC60_RS17935	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CUC60_RS17950	COG0315	cyclic pyranopterin monophosphate synthase activity
CUC60_RS17950	COG0521	Mo-molybdopterin cofactor biosynthetic process
CUC60_RS17955	COG0303	'Molybdopterin
CUC60_RS17965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CUC60_RS17970	COG0697	spore germination
CUC60_RS17990	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CUC60_RS17995	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CUC60_RS18055	COG2204	response regulator
CUC60_RS18060	COG3852	Histidine kinase
CUC60_RS18085	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CUC60_RS18090	COG0575	Belongs to the CDS family
CUC60_RS18125	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUC60_RS18140	COG2137	regulation of response to DNA damage stimulus
CUC60_RS18150	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CUC60_RS18155	COG1011	Hydrolase
CUC60_RS18180	COG1522	sequence-specific DNA binding
CUC60_RS18190	COG1113	amino acid transport
CUC60_RS18205	COG0659	secondary active sulfate transmembrane transporter activity
CUC60_RS18210	COG2135	peptidase activity
CUC60_RS18245	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUC60_RS18245	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CUC60_RS18245	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CUC60_RS18250	COG1105	Belongs to the carbohydrate kinase PfkB family
CUC60_RS18255	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CUC60_RS18255	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CUC60_RS18285	COG0024	Methionine aminopeptidase
CUC60_RS18290	COG0583	DNA-binding transcription factor activity
CUC60_RS18300	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CUC60_RS18305	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CUC60_RS18310	COG0516	GMP reductase activity
CUC60_RS18310	COG0517	IMP dehydrogenase activity
CUC60_RS18335	COG0552	protein localization to endoplasmic reticulum
CUC60_RS18345	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CUC60_RS18360	COG4890	Cyd operon protein YbgT
CUC60_RS18365	COG1294	oxidase, subunit
CUC60_RS18385	COG1585	Membrane protein implicated in regulation of membrane protease activity
CUC60_RS18395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CUC60_RS18400	COG4774	siderophore transport
CUC60_RS18415	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CUC60_RS18420	COG0569	domain protein
CUC60_RS18425	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CUC60_RS18455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CUC60_RS18460	COG0542	response to heat
CUC60_RS18485	COG1902	pentaerythritol trinitrate reductase activity
CUC60_RS18485	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_RS18530	COG2323	membrane
CUC60_RS18535	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CUC60_RS18545	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CUC60_RS18550	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CUC60_RS18555	COG0183	Belongs to the thiolase family
CUC60_RS18560	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CUC60_RS18565	COG0596	Alpha beta hydrolase
CUC60_RS18570	COG2271	Major facilitator Superfamily
CUC60_RS18575	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CUC60_RS18585	COG3485	protocatechuate 3,4-dioxygenase
CUC60_RS18590	COG0710	3-dehydroquinate dehydratase activity
CUC60_RS18600	COG3659	wide pore channel activity
CUC60_RS18605	COG4993	Dehydrogenase
CUC60_RS18615	COG2391	methyltransferase activity
CUC60_RS18635	COG0583	DNA-binding transcription factor activity
CUC60_RS18640	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS18665	COG2814	Major facilitator Superfamily
CUC60_RS18675	COG0154	amidase activity
CUC60_RS18705	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS18715	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CUC60_RS18725	COG3733	amine oxidase
CUC60_RS18735	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS18745	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CUC60_RS18750	COG0183	Belongs to the thiolase family
CUC60_RS18755	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CUC60_RS18760	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CUC60_RS18770	COG4829	muconolactone delta-isomerase
CUC60_RS18780	COG0583	DNA-binding transcription factor activity
CUC60_RS18790	COG2186	Transcriptional regulator
CUC60_RS18810	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS18830	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS18835	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS18840	COG3829	transcription factor binding
CUC60_RS18850	COG3162	membrane
CUC60_RS18865	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS18880	COG0753	catalase activity
CUC60_RS18905	COG1846	Transcriptional regulator
CUC60_RS18910	COG1902	pentaerythritol trinitrate reductase activity
CUC60_RS18910	COG0446	pyridine nucleotide-disulphide oxidoreductase
CUC60_RS18920	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CUC60_RS18950	COG1309	transcriptional regulator
CUC60_RS18960	COG1335	isochorismatase
CUC60_RS18975	COG0475	glutathione-regulated potassium exporter activity
CUC60_RS18975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CUC60_RS18985	COG1473	amidohydrolase
CUC60_RS19000	COG2831	hemolysin activation secretion protein
CUC60_RS19005	COG3210	domain, Protein
CUC60_RS19035	COG2188	Transcriptional regulator
CUC60_RS19050	COG0583	DNA-binding transcription factor activity
CUC60_RS19080	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CUC60_RS19100	COG1566	PFAM secretion protein HlyD family protein
CUC60_RS19115	COG1012	belongs to the aldehyde dehydrogenase family
CUC60_RS19120	COG0129	dihydroxy-acid dehydratase activity
CUC60_RS19130	COG0583	DNA-binding transcription factor activity
CUC60_RS19135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CUC60_RS19145	COG2084	Dehydrogenase
CUC60_RS19150	COG2207	Transcriptional regulator
CUC60_RS19165	COG1064	alcohol dehydrogenase
CUC60_RS19175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CUC60_RS19180	COG1120	ATPase activity
CUC60_RS19200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CUC60_RS19320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CUC60_RS19375	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS19390	COG2207	Transcriptional regulator
CUC60_RS19400	COG2205	protein histidine kinase activity
CUC60_RS19405	COG0745	RESPONSE REGULATOR receiver
CUC60_RS19410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CUC60_RS19415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUC60_RS19420	COG1538	Outer membrane efflux protein
CUC60_RS19430	COG2072	flavoprotein involved in K transport
CUC60_RS19450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CUC60_RS19470	COG3539	Fimbrial protein
CUC60_RS19500	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CUC60_RS19510	COG0753	catalase activity
CUC60_RS19525	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CUC60_RS19590	COG1535	isochorismatase
CUC60_RS19590	COG3433	isochorismatase activity
CUC60_RS19600	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CUC60_RS19605	COG4149	molybdate abc transporter
CUC60_RS19610	COG0725	ABC transporter, periplasmic molybdate-binding protein
CUC60_RS19620	COG4638	Rieske (2fe-2S)
CUC60_RS19625	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CUC60_RS19630	COG0543	2 iron, 2 sulfur cluster binding
CUC60_RS19630	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CUC60_RS19655	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS19670	COG2207	Transcriptional regulator
CUC60_RS19680	COG1028	Short-chain dehydrogenase reductase Sdr
CUC60_RS19685	COG2610	gluconate transmembrane transporter activity
CUC60_RS19695	COG0583	DNA-binding transcription factor activity
CUC60_RS19705	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CUC60_RS19710	COG2031	fatty acid transporter
CUC60_RS19715	COG0183	Belongs to the thiolase family
CUC60_RS19720	COG0583	DNA-binding transcription factor activity
CUC60_RS19725	COG0583	DNA-binding transcription factor activity
CUC60_RS19740	COG1027	Aspartate ammonia-lyase
CUC60_RS19750	COG0477	Major facilitator Superfamily
CUC60_RS19770	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CUC60_RS19775	COG4521	taurine ABC transporter
CUC60_RS19790	COG2188	Transcriptional regulator
CUC60_RS19800	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CUC60_RS19805	COG1733	regulation of RNA biosynthetic process
CUC60_RS19810	COG2207	Transcriptional regulator
CUC60_RS19810	COG3708	Transcriptional regulator
CUC60_RS19825	COG0730	response to heat
CUC60_RS19835	COG3453	Protein conserved in bacteria
CUC60_RS19835	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CUC60_RS19845	COG3781	membrane
CUC60_RS19850	COG1063	alcohol dehydrogenase
CUC60_RS19860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CUC60_RS19865	COG0508	dehydrogenase complex catalyzes the overall conversion of
CUC60_RS19870	COG0022	dehydrogenase e1 component
CUC60_RS19875	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CUC60_RS19895	COG3706	GGDEF domain
CUC60_RS19910	COG0133	tryptophan synthase activity
CUC60_RS19920	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CUC60_RS19955	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CUC60_RS19980	COG2226	methyltransferase
CUC60_RS20035	COG0842	Transport permease protein
CUC60_RS20040	COG0842	Transport permease protein
CUC60_RS20045	COG1131	(ABC) transporter
CUC60_RS20060	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CUC60_RS20065	COG4773	Receptor
CUC60_RS20085	COG0730	response to heat
CUC60_RS20090	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CUC60_RS20110	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CUC60_RS20170	COG4264	IucA IucC family
CUC60_RS20175	COG4264	IucA IucC family
CUC60_RS20195	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CUC60_RS20210	COG1960	acyl-CoA dehydrogenase activity
CUC60_RS20220	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CUC60_RS20225	COG2207	Transcriptional regulator
CUC60_RS20230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CUC60_RS20235	COG0776	regulation of translation
CUC60_RS20260	COG0822	iron-sulfur transferase activity
CUC60_RS20265	COG0316	Belongs to the HesB IscA family
CUC60_RS20315	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CUC60_RS20320	COG0702	epimerase
CUC60_RS20355	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CUC60_RS20415	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CUC60_RS20485	COG0739	heme binding
CUC60_RS20485	COG1196	nuclear chromosome segregation
CUC60_RS20485	COG0741	lytic transglycosylase activity
CUC60_RS20700	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CUC60_RS20790	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
CUC60_RS20855	COG4683	PFAM Phage derived protein Gp49-like (DUF891)