locus-tag	class	description
H7R41_RS00010	COG0592	DNA-directed DNA polymerase activity
H7R41_RS00020	COG0187	DNA topoisomerase II activity
H7R41_RS00030	COG0586	Pfam SNARE associated Golgi protein
H7R41_RS00035	COG0488	(ABC) transporter
H7R41_RS00060	COG0596	Alpha beta hydrolase
H7R41_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
H7R41_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
H7R41_RS00110	COG0733	neurotransmitter:sodium symporter activity
H7R41_RS00145	COG0583	DNA-binding transcription factor activity
H7R41_RS00150	COG2233	PERMEase
H7R41_RS00165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R41_RS00200	COG2814	Major facilitator Superfamily
H7R41_RS00205	COG0656	L-ascorbic acid biosynthetic process
H7R41_RS00210	COG0583	DNA-binding transcription factor activity
H7R41_RS00225	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R41_RS00230	COG1064	alcohol dehydrogenase
H7R41_RS00235	COG2818	Glycosylase
H7R41_RS00250	COG1194	a g-specific adenine glycosylase
H7R41_RS00270	COG2983	Belongs to the UPF0260 family
H7R41_RS00275	COG2133	pyrroloquinoline quinone binding
H7R41_RS00280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
H7R41_RS00285	COG2116	formate transmembrane transporter activity
H7R41_RS00305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R41_RS00310	COG1335	isochorismatase
H7R41_RS00315	COG0385	Bile acid
H7R41_RS00320	COG0534	Mate efflux family protein
H7R41_RS00325	COG1683	Conserved Protein
H7R41_RS00345	COG0625	glutathione transferase activity
H7R41_RS00355	COG1113	amino acid transport
H7R41_RS00365	COG0523	cobalamin synthesis protein
H7R41_RS00375	COG2188	Transcriptional regulator
H7R41_RS00405	COG0010	Belongs to the arginase family
H7R41_RS00415	COG0546	phosphoglycolate phosphatase activity
H7R41_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7R41_RS00425	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H7R41_RS00435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
H7R41_RS00440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
H7R41_RS00485	COG0753	catalase activity
H7R41_RS00535	COG0534	Mate efflux family protein
H7R41_RS00540	COG0436	Aminotransferase
H7R41_RS00545	COG2733	membrane
H7R41_RS00560	COG2918	glutathione biosynthetic process
H7R41_RS00575	COG3179	chitinase
H7R41_RS00595	COG3150	esterase
H7R41_RS00605	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
H7R41_RS00615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R41_RS00625	COG2233	PERMEase
H7R41_RS00630	COG2351	hydroxyisourate hydrolase activity
H7R41_RS00665	COG3706	GGDEF domain
H7R41_RS00680	COG1393	Belongs to the ArsC family
H7R41_RS00685	COG0708	Exodeoxyribonuclease III
H7R41_RS00710	COG0189	ligase activity
H7R41_RS00730	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
H7R41_RS00740	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H7R41_RS00755	COG4942	peptidase
H7R41_RS00765	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7R41_RS00775	COG2119	membrane
H7R41_RS00780	COG4774	siderophore transport
H7R41_RS00785	COG0426	domain, Protein
H7R41_RS00785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R41_RS00810	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
H7R41_RS00835	COG1902	pentaerythritol trinitrate reductase activity
H7R41_RS00840	COG1519	Transferase
H7R41_RS00845	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7R41_RS00850	COG0668	transmembrane transport
H7R41_RS00860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7R41_RS00865	COG1335	isochorismatase
H7R41_RS00870	COG1522	sequence-specific DNA binding
H7R41_RS00895	COG0784	Response regulator, receiver
H7R41_RS00895	COG2198	Histidine kinase
H7R41_RS00895	COG2205	protein histidine kinase activity
H7R41_RS00900	COG3162	membrane
H7R41_RS00905	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7R41_RS00915	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7R41_RS00930	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H7R41_RS00935	COG1309	transcriptional regulator
H7R41_RS00955	COG0351	phosphomethylpyrimidine kinase
H7R41_RS00955	COG0352	thiamine-phosphate diphosphorylase activity
H7R41_RS00955	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7R41_RS00965	COG2814	Major facilitator Superfamily
H7R41_RS00985	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7R41_RS00995	COG1113	amino acid transport
H7R41_RS01005	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7R41_RS01010	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS01020	COG1335	isochorismatase
H7R41_RS01050	COG2814	Major facilitator Superfamily
H7R41_RS01055	COG0583	DNA-binding transcription factor activity
H7R41_RS01075	COG0667	Aldo Keto reductase
H7R41_RS01110	COG1733	regulation of RNA biosynthetic process
H7R41_RS01115	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R41_RS01120	COG0318	PFAM AMP-dependent synthetase and ligase
H7R41_RS01125	COG1881	PFAM PEBP family protein
H7R41_RS01135	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
H7R41_RS01140	COG2207	Transcriptional regulator
H7R41_RS01195	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
H7R41_RS01250	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
H7R41_RS01280	COG0427	acetyl-CoA hydrolase
H7R41_RS01305	COG0659	secondary active sulfate transmembrane transporter activity
H7R41_RS01310	COG4221	oxidoreductase activity
H7R41_RS01315	COG2873	o-acetylhomoserine
H7R41_RS01320	COG0488	(ABC) transporter
H7R41_RS01385	COG0833	amino acid
H7R41_RS01430	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
H7R41_RS01435	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H7R41_RS01450	COG2226	methyltransferase
H7R41_RS01500	COG0067	glutamate synthase
H7R41_RS01500	COG0069	glutamate synthase activity
H7R41_RS01500	COG0070	glutamate synthase
H7R41_RS01505	COG0493	'glutamate synthase
H7R41_RS01515	COG1704	LemA family
H7R41_RS01520	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
H7R41_RS01540	COG3307	-O-antigen
H7R41_RS01560	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7R41_RS01575	COG0194	GDP metabolic process
H7R41_RS01625	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
H7R41_RS01645	COG5380	lipid catabolic process
H7R41_RS01650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
H7R41_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H7R41_RS01680	COG0277	FAD linked oxidase domain protein
H7R41_RS01690	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
H7R41_RS01695	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R41_RS01710	COG1289	transmembrane transporter activity
H7R41_RS01720	COG0628	permease
H7R41_RS01725	COG1192	Involved in chromosome partitioning
H7R41_RS01755	COG0833	amino acid
H7R41_RS01760	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7R41_RS01765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7R41_RS01775	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS01815	COG0583	DNA-binding transcription factor activity
H7R41_RS01840	COG0752	glycyl-tRNA synthetase alpha subunit
H7R41_RS01865	COG0517	IMP dehydrogenase activity
H7R41_RS01870	COG1983	PspC domain protein
H7R41_RS01880	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS01895	COG0408	coproporphyrinogen oxidase activity
H7R41_RS01915	COG0513	Belongs to the DEAD box helicase family
H7R41_RS01925	COG1127	ABC transporter
H7R41_RS01930	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
H7R41_RS01940	COG2854	intermembrane phospholipid transfer
H7R41_RS01950	COG0598	Magnesium transport protein CorA
H7R41_RS01965	COG1040	competence protein
H7R41_RS01970	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
H7R41_RS01990	COG1946	Acyl-CoA thioesterase
H7R41_RS01995	COG1301	dicarboxylic acid transport
H7R41_RS02010	COG1959	2 iron, 2 sulfur cluster binding
H7R41_RS02015	COG1017	nitric oxide dioxygenase activity
H7R41_RS02015	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R41_RS02020	COG0433	COG0433 Predicted ATPase
H7R41_RS02025	COG0626	cystathionine gamma-synthase activity
H7R41_RS02180	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS02185	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
H7R41_RS02215	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
H7R41_RS02220	COG0339	signal peptide processing
H7R41_RS02225	COG0557	exoribonuclease II activity
H7R41_RS02270	COG0179	Fumarylacetoacetate (FAA) hydrolase
H7R41_RS02275	COG2169	Transcriptional regulator
H7R41_RS02280	COG0697	spore germination
H7R41_RS02285	COG1295	ribonuclease BN
H7R41_RS02320	COG1702	phosphate starvation-inducible protein PhoH
H7R41_RS02330	COG0739	heme binding
H7R41_RS02330	COG0741	lytic transglycosylase activity
H7R41_RS02330	COG1196	nuclear chromosome segregation
H7R41_RS02360	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
H7R41_RS02365	COG1183	phosphatidylcholine synthase activity
H7R41_RS02410	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS02415	COG1309	transcriptional regulator
H7R41_RS02430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7R41_RS02435	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS02455	COG2969	positive regulation of protein catabolic process
H7R41_RS02465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
H7R41_RS02475	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
H7R41_RS02480	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7R41_RS02485	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
H7R41_RS02505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H7R41_RS02515	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R41_RS02520	COG1408	metallophosphoesterase
H7R41_RS02530	COG2199	diguanylate cyclase activity
H7R41_RS02590	COG1607	acyl-coa hydrolase
H7R41_RS02620	COG2350	Protein conserved in bacteria
H7R41_RS02630	COG0613	PHP domain protein
H7R41_RS02635	COG3781	membrane
H7R41_RS02645	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
H7R41_RS02650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
H7R41_RS02660	COG1862	Preprotein translocase
H7R41_RS02690	COG0582	viral genome integration into host DNA
H7R41_RS02720	COG2205	protein histidine kinase activity
H7R41_RS02725	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
H7R41_RS02740	COG0726	polysaccharide deacetylase
H7R41_RS02745	COG0438	transferase activity, transferring glycosyl groups
H7R41_RS02760	COG1091	dTDP-4-dehydrorhamnose reductase activity
H7R41_RS02775	COG1215	transferase activity, transferring glycosyl groups
H7R41_RS02825	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS02830	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS02840	COG2205	protein histidine kinase activity
H7R41_RS02845	COG0745	RESPONSE REGULATOR receiver
H7R41_RS02850	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
H7R41_RS02870	COG2096	Adenosyltransferase
H7R41_RS02875	COG4206	TonB-dependent receptor
H7R41_RS02920	COG0285	dihydrofolate synthase activity
H7R41_RS02940	COG0450	alkyl hydroperoxide reductase
H7R41_RS02955	COG0477	Major facilitator Superfamily
H7R41_RS02960	COG1272	protein, Hemolysin III
H7R41_RS02990	COG0183	Belongs to the thiolase family
H7R41_RS02995	COG2207	Transcriptional regulator
H7R41_RS03015	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R41_RS03035	COG0183	Belongs to the thiolase family
H7R41_RS03045	COG2885	chlorophyll binding
H7R41_RS03045	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
H7R41_RS03055	COG1690	Belongs to the RtcB family
H7R41_RS03060	COG0833	amino acid
H7R41_RS03070	COG2233	PERMEase
H7R41_RS03075	COG1217	gtp-binding protein TYPA
H7R41_RS03100	COG2094	Belongs to the DNA glycosylase MPG family
H7R41_RS03105	COG4772	TonB-dependent receptor
H7R41_RS03110	COG1902	pentaerythritol trinitrate reductase activity
H7R41_RS03115	COG0679	Auxin Efflux Carrier
H7R41_RS03125	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R41_RS03130	COG0354	folic acid binding
H7R41_RS03140	COG3189	MarR family transcriptional regulator
H7R41_RS03145	COG2824	Alkylphosphonate utilization operon protein PhnA
H7R41_RS03150	COG3422	double-strand break repair
H7R41_RS03190	COG0840	transmembrane signaling receptor activity
H7R41_RS03215	COG5510	response to toxic substance
H7R41_RS03225	COG2832	Protein of unknown function (DUF454)
H7R41_RS03230	COG1376	ErfK ybiS ycfS ynhG family protein
H7R41_RS03270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
H7R41_RS03280	COG1289	transmembrane transporter activity
H7R41_RS03285	COG2814	Major facilitator Superfamily
H7R41_RS03305	COG1115	amino acid carrier protein
H7R41_RS03310	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7R41_RS03315	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7R41_RS03320	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
H7R41_RS03325	COG3590	peptidase
H7R41_RS03350	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7R41_RS03360	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
H7R41_RS03365	COG1077	Cell shape determining protein MreB Mrl
H7R41_RS03370	COG1792	Involved in formation and maintenance of cell shape
H7R41_RS03375	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
H7R41_RS03380	COG0424	maF-like protein
H7R41_RS03385	COG1530	ribonuclease E activity
H7R41_RS03395	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R41_RS03405	COG0560	Phosphoserine phosphatase
H7R41_RS03415	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R41_RS03440	COG2207	Transcriptional regulator
H7R41_RS03460	COG1113	amino acid transport
H7R41_RS03465	COG2828	Protein conserved in bacteria
H7R41_RS03470	COG0142	geranyltranstransferase activity
H7R41_RS03475	COG2315	Protein conserved in bacteria
H7R41_RS03490	COG1752	Esterase of the alpha-beta hydrolase superfamily
H7R41_RS03510	COG2194	sulfuric ester hydrolase activity
H7R41_RS03515	COG0745	RESPONSE REGULATOR receiver
H7R41_RS03520	COG0642	Histidine kinase
H7R41_RS03530	COG0004	ammonium transporteR
H7R41_RS03535	COG0583	DNA-binding transcription factor activity
H7R41_RS03555	COG0525	valine-tRNA ligase activity
H7R41_RS03565	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS03575	COG0393	Putative heavy-metal-binding
H7R41_RS03580	COG0393	Putative heavy-metal-binding
H7R41_RS03585	COG1538	Outer membrane efflux protein
H7R41_RS03595	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R41_RS03600	COG0671	phosphoesterase, PA-phosphatase related
H7R41_RS03630	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
H7R41_RS03645	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
H7R41_RS03645	COG1648	precorrin-2 dehydrogenase activity
H7R41_RS03650	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H7R41_RS03655	COG1733	regulation of RNA biosynthetic process
H7R41_RS03665	COG0531	amino acid
H7R41_RS03680	COG0321	lipoyl(octanoyl) transferase activity
H7R41_RS03685	COG2921	Belongs to the UPF0250 family
H7R41_RS03725	COG2009	succinate dehydrogenase
H7R41_RS03730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
H7R41_RS03735	COG1053	succinate dehydrogenase
H7R41_RS03740	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
H7R41_RS03765	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R41_RS03785	COG2354	Protein conserved in bacteria
H7R41_RS03790	COG2321	neutral zinc metallopeptidase
H7R41_RS03820	COG2843	Capsule synthesis protein
H7R41_RS03835	COG0589	response to stress
H7R41_RS03845	COG0251	oxidation-reduction process
H7R41_RS03850	COG1309	transcriptional regulator
H7R41_RS03865	COG0505	Belongs to the CarA family
H7R41_RS03890	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7R41_RS03895	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H7R41_RS03945	COG0477	Major facilitator Superfamily
H7R41_RS03950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
H7R41_RS03965	COG1597	lipid kinase activity
H7R41_RS03970	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7R41_RS03990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R41_RS03995	COG0584	glycerophosphoryl diester phosphodiesterase
H7R41_RS04015	COG0741	lytic transglycosylase activity
H7R41_RS04035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H7R41_RS04050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R41_RS04060	COG3811	Belongs to the UPF0386 family
H7R41_RS04120	COG0778	Nitroreductase
H7R41_RS04135	COG1929	Belongs to the glycerate kinase type-1 family
H7R41_RS04140	COG0243	molybdopterin cofactor binding
H7R41_RS04145	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
H7R41_RS04150	COG3339	Conserved Protein
H7R41_RS04160	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
H7R41_RS04175	COG1113	amino acid transport
H7R41_RS04185	COG0019	diaminopimelate decarboxylase activity
H7R41_RS04195	COG1280	lysine exporter protein (LysE YggA)
H7R41_RS04200	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H7R41_RS04230	COG0463	Glycosyl transferase, family 2
H7R41_RS04250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R41_RS04280	COG4591	ABC-type transport system involved in lipoprotein release permease component
H7R41_RS04285	COG1136	(ABC) transporter
H7R41_RS04290	COG2333	competence protein COMEC
H7R41_RS04290	COG0658	competence protein
H7R41_RS04300	COG0616	signal peptide processing
H7R41_RS04300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
H7R41_RS04305	COG0596	Alpha beta hydrolase
H7R41_RS04310	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
H7R41_RS04320	COG0628	permease
H7R41_RS04355	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7R41_RS04375	COG0823	Involved in the tonB-independent uptake of proteins
H7R41_RS04395	COG0824	Thioesterase
H7R41_RS04400	COG1473	amidohydrolase
H7R41_RS04420	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H7R41_RS04420	COG0047	phosphoribosylformylglycinamidine synthase activity
H7R41_RS04425	COG2814	Major facilitator Superfamily
H7R41_RS04435	COG1024	Enoyl-CoA hydratase
H7R41_RS04440	COG1056	cytidyltransferase-related domain
H7R41_RS04440	COG1051	belongs to the nudix hydrolase family
H7R41_RS04450	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H7R41_RS04465	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
H7R41_RS04480	COG4625	pathogenesis
H7R41_RS04485	COG0583	DNA-binding transcription factor activity
H7R41_RS04490	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
H7R41_RS04495	COG4208	sulfate ABC transporter
H7R41_RS04500	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
H7R41_RS04510	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
H7R41_RS04515	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H7R41_RS04520	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
H7R41_RS04540	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R41_RS04550	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H7R41_RS04560	COG0681	Belongs to the peptidase S26 family
H7R41_RS04575	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
H7R41_RS04585	COG1381	Involved in DNA repair and RecF pathway recombination
H7R41_RS04590	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
H7R41_RS04600	COG4221	oxidoreductase activity
H7R41_RS04630	COG0443	Heat shock 70 kDa protein
H7R41_RS04640	COG0436	Aminotransferase
H7R41_RS04660	COG0556	nucleotide-excision repair
H7R41_RS04715	COG2070	2-Nitropropane dioxygenase
H7R41_RS04760	COG0415	Belongs to the DNA photolyase family
H7R41_RS04770	COG1252	NADH dehydrogenase
H7R41_RS04775	COG1686	Belongs to the peptidase S11 family
H7R41_RS04790	COG1187	pseudouridine synthase activity
H7R41_RS04815	COG0477	Major facilitator Superfamily
H7R41_RS04820	COG0583	DNA-binding transcription factor activity
H7R41_RS04825	COG1823	symporter activity
H7R41_RS04835	COG0612	Peptidase, M16
H7R41_RS04860	COG0352	thiamine-phosphate diphosphorylase activity
H7R41_RS04895	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R41_RS04905	COG2249	NAD(P)H dehydrogenase (quinone) activity
H7R41_RS04920	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
H7R41_RS04925	COG0076	glutamate decarboxylase activity
H7R41_RS04935	COG1522	sequence-specific DNA binding
H7R41_RS04940	COG3961	Belongs to the TPP enzyme family
H7R41_RS04945	COG1113	amino acid transport
H7R41_RS04950	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
H7R41_RS04955	COG0573	inorganic phosphate transmembrane transporter activity
H7R41_RS04965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
H7R41_RS04970	COG0616	signal peptide processing
H7R41_RS05005	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
H7R41_RS05010	COG1686	Belongs to the peptidase S11 family
H7R41_RS05035	COG0583	DNA-binding transcription factor activity
H7R41_RS05040	COG1067	ATP-dependent peptidase activity
H7R41_RS05065	COG4943	cyclic-guanylate-specific phosphodiesterase activity
H7R41_RS05085	COG1966	Carbon starvation protein
H7R41_RS05090	COG2879	small protein
H7R41_RS05130	COG1335	isochorismatase
H7R41_RS05135	COG0583	DNA-binding transcription factor activity
H7R41_RS05150	COG0596	Alpha beta hydrolase
H7R41_RS05160	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7R41_RS05200	COG1741	Belongs to the pirin family
H7R41_RS05210	COG2964	Protein conserved in bacteria
H7R41_RS05225	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R41_RS05230	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R41_RS05235	COG4605	iron ion homeostasis
H7R41_RS05240	COG4604	ABC transporter, ATP-binding protein
H7R41_RS05245	COG4607	ABC-type enterochelin transport system periplasmic component
H7R41_RS05250	COG4774	siderophore transport
H7R41_RS05260	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
H7R41_RS05265	COG1021	2,3-dihydroxybenzoate-AMP ligase
H7R41_RS05270	COG3433	isochorismatase activity
H7R41_RS05270	COG1535	isochorismatase
H7R41_RS05280	COG1132	(ABC) transporter
H7R41_RS05285	COG1132	(ABC) transporter
H7R41_RS05290	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
H7R41_RS05315	COG3739	integral membrane protein
H7R41_RS05335	COG0302	gtp cyclohydrolase
H7R41_RS05345	COG1529	Aldehyde oxidase and xanthine dehydrogenase
H7R41_RS05375	COG0308	aminopeptidase N
H7R41_RS05380	COG0512	Glutamine amidotransferase of anthranilate synthase
H7R41_RS05395	COG0174	glutamine synthetase
H7R41_RS05405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
H7R41_RS05440	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
H7R41_RS05445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H7R41_RS05450	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
H7R41_RS05470	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H7R41_RS05475	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H7R41_RS05480	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H7R41_RS05495	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS05500	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7R41_RS05505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R41_RS05515	COG2223	nitrite transmembrane transporter activity
H7R41_RS05525	COG0024	Methionine aminopeptidase
H7R41_RS05530	COG0052	Belongs to the universal ribosomal protein uS2 family
H7R41_RS05545	COG2207	Transcriptional regulator
H7R41_RS05570	COG2951	lytic endotransglycosylase activity
H7R41_RS05575	COG0772	Belongs to the SEDS family
H7R41_RS05590	COG0842	Transport permease protein
H7R41_RS05595	COG1131	(ABC) transporter
H7R41_RS05640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R41_RS05655	COG4215	(ABC) transporter
H7R41_RS05660	COG4160	amino acid transport
H7R41_RS05665	COG4598	ABC transporter
H7R41_RS05675	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R41_RS05680	COG0826	peptidase U32
H7R41_RS05685	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R41_RS05700	COG1720	tRNA m6t6A37 methyltransferase activity
H7R41_RS05710	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
H7R41_RS05725	COG0642	Histidine kinase
H7R41_RS05735	COG0494	nUDIX hydrolase
H7R41_RS05745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H7R41_RS05750	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
H7R41_RS05755	COG3139	Protein of unknown function (DUF1315)
H7R41_RS05760	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H7R41_RS05765	COG1301	dicarboxylic acid transport
H7R41_RS05770	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS05775	COG2819	hydrolase of the alpha beta superfamily
H7R41_RS05785	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
H7R41_RS05795	COG2195	Cleaves the N-terminal amino acid of tripeptides
H7R41_RS05815	COG1690	Belongs to the RtcB family
H7R41_RS05820	COG1234	tRNA 3'-trailer cleavage
H7R41_RS05825	COG4650	regulator
H7R41_RS05855	COG2363	Small membrane protein
H7R41_RS05875	COG0513	Belongs to the DEAD box helicase family
H7R41_RS05885	COG0778	Nitroreductase
H7R41_RS05915	COG1286	toxin biosynthetic process
H7R41_RS05940	COG4783	chaperone-mediated protein folding
H7R41_RS05945	COG1610	YqeY-like protein
H7R41_RS05975	COG2815	serine threonine protein kinase
H7R41_RS05975	COG0515	serine threonine protein kinase
H7R41_RS06045	COG3111	PFAM Bacterial OB fold (BOF) protein
H7R41_RS06070	COG3243	poly(R)-hydroxyalkanoic acid synthase
H7R41_RS06075	COG0786	glutamate:sodium symporter activity
H7R41_RS06085	COG2186	Transcriptional regulator
H7R41_RS06135	COG0477	Major facilitator Superfamily
H7R41_RS06140	COG1051	belongs to the nudix hydrolase family
H7R41_RS06170	COG2995	paraquat-inducible protein a
H7R41_RS06175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
H7R41_RS06175	COG3008	intermembrane lipid transfer
H7R41_RS06190	COG1794	racemase activity, acting on amino acids and derivatives
H7R41_RS06225	COG1301	dicarboxylic acid transport
H7R41_RS06235	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R41_RS06240	COG2011	ABC-type metal ion transport system permease component
H7R41_RS06245	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7R41_RS06250	COG1464	Belongs to the NlpA lipoprotein family
H7R41_RS06255	COG0151	Belongs to the GarS family
H7R41_RS06260	COG0138	bifunctional purine biosynthesis protein purh
H7R41_RS06265	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
H7R41_RS06295	COG2308	Evidence 4 Homologs of previously reported genes of
H7R41_RS06305	COG1305	Transglutaminase-like
H7R41_RS06315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H7R41_RS06320	COG0305	Participates in initiation and elongation during chromosome replication
H7R41_RS06345	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
H7R41_RS06355	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
H7R41_RS06360	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
H7R41_RS06385	COG0726	polysaccharide deacetylase
H7R41_RS06385	COG1649	PFAM Uncharacterised BCR, COG1649
H7R41_RS06395	COG3658	cytochrome
H7R41_RS06405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R41_RS06420	COG0583	DNA-binding transcription factor activity
H7R41_RS06450	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS06455	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7R41_RS06460	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R41_RS06475	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H7R41_RS06485	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
H7R41_RS06490	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
H7R41_RS06495	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
H7R41_RS06500	COG2205	protein histidine kinase activity
H7R41_RS06505	COG0745	RESPONSE REGULATOR receiver
H7R41_RS06510	COG0174	glutamine synthetase
H7R41_RS06530	COG0729	surface antigen
H7R41_RS06555	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7R41_RS06560	COG2814	Major facilitator Superfamily
H7R41_RS06575	COG0583	DNA-binding transcription factor activity
H7R41_RS06590	COG1187	pseudouridine synthase activity
H7R41_RS06610	COG0802	atpase or kinase
H7R41_RS06615	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
H7R41_RS06625	COG1923	regulation of RNA biosynthetic process
H7R41_RS06630	COG0697	spore germination
H7R41_RS06655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7R41_RS06660	COG0519	Catalyzes the synthesis of GMP from XMP
H7R41_RS06660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7R41_RS06665	COG4302	ethanolamine ammonia-lyase activity
H7R41_RS06670	COG4303	Ethanolamine ammonia lyase large subunit
H7R41_RS06675	COG0531	amino acid
H7R41_RS06695	COG1454	alcohol dehydrogenase
H7R41_RS06700	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7R41_RS06725	COG0308	aminopeptidase N
H7R41_RS06745	COG1605	Chorismate mutase
H7R41_RS06785	COG0668	transmembrane transport
H7R41_RS06815	COG4773	Receptor
H7R41_RS06835	COG0488	(ABC) transporter
H7R41_RS06840	COG0589	response to stress
H7R41_RS06865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H7R41_RS06875	COG3135	benzoate transporter
H7R41_RS06880	COG1522	sequence-specific DNA binding
H7R41_RS06890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H7R41_RS06895	COG0583	DNA-binding transcription factor activity
H7R41_RS06905	COG0183	Belongs to the thiolase family
H7R41_RS06915	COG2030	dehydratase
H7R41_RS06920	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7R41_RS06935	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
H7R41_RS06945	COG0824	Thioesterase
H7R41_RS06950	COG1454	alcohol dehydrogenase
H7R41_RS06960	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H7R41_RS06980	COG0069	glutamate synthase activity
H7R41_RS07015	COG2814	Major facilitator Superfamily
H7R41_RS07030	COG0511	ligase activity, forming carbon-carbon bonds
H7R41_RS07050	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R41_RS07050	COG1116	anion transmembrane transporter activity
H7R41_RS07055	COG0745	RESPONSE REGULATOR receiver
H7R41_RS07065	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R41_RS07065	COG2146	nitrite reductase [NAD(P)H] activity
H7R41_RS07070	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R41_RS07075	COG0243	molybdopterin cofactor binding
H7R41_RS07085	COG0243	molybdopterin cofactor binding
H7R41_RS07090	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
H7R41_RS07105	COG0521	Mo-molybdopterin cofactor biosynthetic process
H7R41_RS07105	COG0315	cyclic pyranopterin monophosphate synthase activity
H7R41_RS07110	COG0303	'Molybdopterin
H7R41_RS07120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R41_RS07125	COG0697	spore germination
H7R41_RS07145	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
H7R41_RS07150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7R41_RS07205	COG2204	response regulator
H7R41_RS07210	COG3852	Histidine kinase
H7R41_RS07235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
H7R41_RS07240	COG0575	Belongs to the CDS family
H7R41_RS07255	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R41_RS07275	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7R41_RS07290	COG2137	regulation of response to DNA damage stimulus
H7R41_RS07300	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
H7R41_RS07305	COG1011	Hydrolase
H7R41_RS07330	COG1522	sequence-specific DNA binding
H7R41_RS07340	COG1113	amino acid transport
H7R41_RS07355	COG0659	secondary active sulfate transmembrane transporter activity
H7R41_RS07360	COG2135	peptidase activity
H7R41_RS07390	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R41_RS07390	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
H7R41_RS07390	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
H7R41_RS07395	COG1105	Belongs to the carbohydrate kinase PfkB family
H7R41_RS07400	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R41_RS07400	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H7R41_RS07430	COG0024	Methionine aminopeptidase
H7R41_RS07435	COG0583	DNA-binding transcription factor activity
H7R41_RS07445	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
H7R41_RS07450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
H7R41_RS07455	COG0517	IMP dehydrogenase activity
H7R41_RS07455	COG0516	GMP reductase activity
H7R41_RS07480	COG0552	protein localization to endoplasmic reticulum
H7R41_RS07490	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
H7R41_RS07505	COG4890	Cyd operon protein YbgT
H7R41_RS07510	COG1294	oxidase, subunit
H7R41_RS07525	COG1585	Membrane protein implicated in regulation of membrane protease activity
H7R41_RS07535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H7R41_RS07540	COG4774	siderophore transport
H7R41_RS07555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H7R41_RS07560	COG0569	domain protein
H7R41_RS07565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H7R41_RS07595	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
H7R41_RS07600	COG0542	response to heat
H7R41_RS07625	COG1902	pentaerythritol trinitrate reductase activity
H7R41_RS07625	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R41_RS07670	COG2323	membrane
H7R41_RS07675	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
H7R41_RS07685	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7R41_RS07690	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R41_RS07695	COG0183	Belongs to the thiolase family
H7R41_RS07700	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H7R41_RS07705	COG0596	Alpha beta hydrolase
H7R41_RS07710	COG2271	Major facilitator Superfamily
H7R41_RS07715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R41_RS07720	COG3485	protocatechuate 3,4-dioxygenase
H7R41_RS07725	COG3485	protocatechuate 3,4-dioxygenase
H7R41_RS07730	COG0710	3-dehydroquinate dehydratase activity
H7R41_RS07735	COG3420	alginic acid biosynthetic process
H7R41_RS07740	COG3659	wide pore channel activity
H7R41_RS07745	COG4993	Dehydrogenase
H7R41_RS07755	COG2391	methyltransferase activity
H7R41_RS07770	COG1414	Transcriptional regulator
H7R41_RS07775	COG0583	DNA-binding transcription factor activity
H7R41_RS07780	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS07805	COG2814	Major facilitator Superfamily
H7R41_RS07815	COG0154	amidase activity
H7R41_RS07835	COG4638	Rieske (2fe-2S)
H7R41_RS07845	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS07855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R41_RS07865	COG3733	amine oxidase
H7R41_RS07875	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS07885	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7R41_RS07890	COG0183	Belongs to the thiolase family
H7R41_RS07895	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R41_RS07900	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7R41_RS07910	COG4829	muconolactone delta-isomerase
H7R41_RS07915	COG4948	Mandelate Racemase Muconate Lactonizing
H7R41_RS07920	COG0583	DNA-binding transcription factor activity
H7R41_RS07930	COG2186	Transcriptional regulator
H7R41_RS07950	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS07965	COG1902	pentaerythritol trinitrate reductase activity
H7R41_RS07965	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R41_RS07975	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
H7R41_RS07985	COG0789	Transcriptional regulator
H7R41_RS08010	COG1309	transcriptional regulator
H7R41_RS08015	COG0583	DNA-binding transcription factor activity
H7R41_RS08020	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS08025	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS08030	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS08040	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS08050	COG0318	PFAM AMP-dependent synthetase and ligase
H7R41_RS08125	COG2188	Transcriptional regulator
H7R41_RS08140	COG0583	DNA-binding transcription factor activity
H7R41_RS08155	COG1566	PFAM secretion protein HlyD family protein
H7R41_RS08170	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS08175	COG0129	dihydroxy-acid dehydratase activity
H7R41_RS08185	COG0583	DNA-binding transcription factor activity
H7R41_RS08190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
H7R41_RS08200	COG2084	Dehydrogenase
H7R41_RS08205	COG2207	Transcriptional regulator
H7R41_RS08210	COG1064	alcohol dehydrogenase
H7R41_RS08220	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
H7R41_RS08225	COG1120	ATPase activity
H7R41_RS08320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
H7R41_RS08355	COG2856	Zn peptidase
H7R41_RS08405	COG2207	Transcriptional regulator
H7R41_RS08420	COG2205	protein histidine kinase activity
H7R41_RS08425	COG0745	RESPONSE REGULATOR receiver
H7R41_RS08430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R41_RS08435	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R41_RS08465	COG3539	Fimbrial protein
H7R41_RS08495	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
H7R41_RS08505	COG0753	catalase activity
H7R41_RS08520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
H7R41_RS08585	COG3433	isochorismatase activity
H7R41_RS08585	COG1535	isochorismatase
H7R41_RS08590	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS08595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
H7R41_RS08600	COG4149	molybdate abc transporter
H7R41_RS08605	COG0725	ABC transporter, periplasmic molybdate-binding protein
H7R41_RS08615	COG4638	Rieske (2fe-2S)
H7R41_RS08620	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H7R41_RS08625	COG0543	2 iron, 2 sulfur cluster binding
H7R41_RS08625	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R41_RS08640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R41_RS08650	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS08665	COG2207	Transcriptional regulator
H7R41_RS08670	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS08675	COG2610	gluconate transmembrane transporter activity
H7R41_RS08685	COG1309	transcriptional regulator
H7R41_RS08705	COG0583	DNA-binding transcription factor activity
H7R41_RS08720	COG2031	fatty acid transporter
H7R41_RS08725	COG0183	Belongs to the thiolase family
H7R41_RS08730	COG0583	DNA-binding transcription factor activity
H7R41_RS08735	COG0583	DNA-binding transcription factor activity
H7R41_RS08750	COG1027	Aspartate ammonia-lyase
H7R41_RS08760	COG0477	Major facilitator Superfamily
H7R41_RS08780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R41_RS08785	COG4521	taurine ABC transporter
H7R41_RS08800	COG2188	Transcriptional regulator
H7R41_RS08810	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
H7R41_RS08815	COG1733	regulation of RNA biosynthetic process
H7R41_RS08820	COG2207	Transcriptional regulator
H7R41_RS08820	COG3708	Transcriptional regulator
H7R41_RS08835	COG0730	response to heat
H7R41_RS08845	COG3453	Protein conserved in bacteria
H7R41_RS08845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R41_RS08855	COG3781	membrane
H7R41_RS08860	COG1063	alcohol dehydrogenase
H7R41_RS08870	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H7R41_RS08875	COG0508	dehydrogenase complex catalyzes the overall conversion of
H7R41_RS08880	COG0022	dehydrogenase e1 component
H7R41_RS08885	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
H7R41_RS08890	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
H7R41_RS08905	COG3706	GGDEF domain
H7R41_RS08920	COG0133	tryptophan synthase activity
H7R41_RS08930	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H7R41_RS08960	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
H7R41_RS08965	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
H7R41_RS08990	COG2226	methyltransferase
H7R41_RS09045	COG0842	Transport permease protein
H7R41_RS09050	COG0842	Transport permease protein
H7R41_RS09055	COG1131	(ABC) transporter
H7R41_RS09070	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
H7R41_RS09075	COG4773	Receptor
H7R41_RS09095	COG0730	response to heat
H7R41_RS09100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H7R41_RS09115	COG0406	alpha-ribazole phosphatase activity
H7R41_RS09120	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
H7R41_RS09135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R41_RS09165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7R41_RS09175	COG4264	IucA IucC family
H7R41_RS09180	COG4264	IucA IucC family
H7R41_RS09185	COG2814	Major facilitator Superfamily
H7R41_RS09200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H7R41_RS09215	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS09220	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS09225	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
H7R41_RS09230	COG2207	Transcriptional regulator
H7R41_RS09235	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7R41_RS09240	COG0776	regulation of translation
H7R41_RS09265	COG0822	iron-sulfur transferase activity
H7R41_RS09270	COG0316	Belongs to the HesB IscA family
H7R41_RS09300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7R41_RS09320	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
H7R41_RS09325	COG0702	epimerase
H7R41_RS09360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H7R41_RS09370	COG0339	signal peptide processing
H7R41_RS09420	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
H7R41_RS09425	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
H7R41_RS09455	COG0776	regulation of translation
H7R41_RS09520	COG0084	hydrolase, TatD family'
H7R41_RS09540	COG1663	tetraacyldisaccharide 4'-kinase activity
H7R41_RS09545	COG1132	(ABC) transporter
H7R41_RS09555	COG0811	peptide transport
H7R41_RS09560	COG1475	DNA binding
H7R41_RS09565	COG1192	Involved in chromosome partitioning
H7R41_RS09575	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
H7R41_RS09590	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
H7R41_RS09595	COG0191	fructose-bisphosphate aldolase activity
H7R41_RS09615	COG0424	maF-like protein
H7R41_RS09620	COG2850	peptidyl-arginine hydroxylation
H7R41_RS09630	COG0640	Transcriptional regulator
H7R41_RS09640	COG3619	membrane
H7R41_RS09645	COG3122	Protein conserved in bacteria
H7R41_RS09650	COG1132	(ABC) transporter
H7R41_RS09670	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H7R41_RS09675	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H7R41_RS09685	COG0506	proline dehydrogenase activity
H7R41_RS09685	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7R41_RS09685	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
H7R41_RS09690	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
H7R41_RS09705	COG3698	Phosphodiester glycosidase
H7R41_RS09715	COG2353	YceI-like domain
H7R41_RS09725	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
H7R41_RS09770	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
H7R41_RS09770	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
H7R41_RS09795	COG3539	Fimbrial protein
H7R41_RS09800	COG3121	Chaperone
H7R41_RS09825	COG0697	spore germination
H7R41_RS09835	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7R41_RS09845	COG0583	DNA-binding transcription factor activity
H7R41_RS09865	COG1309	transcriptional regulator
H7R41_RS09880	COG1522	sequence-specific DNA binding
H7R41_RS09890	COG1126	abc transporter atp-binding protein
H7R41_RS09895	COG0765	amino acid transport
H7R41_RS09900	COG0765	amino acid transport
H7R41_RS09930	COG1464	Belongs to the NlpA lipoprotein family
H7R41_RS09940	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7R41_RS09945	COG2011	ABC-type metal ion transport system permease component
H7R41_RS09950	COG0012	GTP binding
H7R41_RS09975	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H7R41_RS10015	COG0386	Belongs to the glutathione peroxidase family
H7R41_RS10025	COG0436	Aminotransferase
H7R41_RS10030	COG1301	dicarboxylic acid transport
H7R41_RS10065	COG3634	alkyl hydroperoxide reductase activity
H7R41_RS10080	COG0583	DNA-binding transcription factor activity
H7R41_RS10085	COG0798	PFAM Bile acid sodium symporter
H7R41_RS10090	COG0640	Transcriptional regulator
H7R41_RS10105	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
H7R41_RS10115	COG0583	DNA-binding transcription factor activity
H7R41_RS10125	COG1953	Uracil, thiamine, allantoin
H7R41_RS10135	COG2175	clavaminate synthase activity
H7R41_RS10140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R41_RS10145	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
H7R41_RS10150	COG4521	taurine ABC transporter
H7R41_RS10160	COG0477	Major facilitator Superfamily
H7R41_RS10180	COG1271	oxidase subunit
H7R41_RS10185	COG1294	oxidase, subunit
H7R41_RS10195	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R41_RS10215	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
H7R41_RS10235	COG3052	prosthetic group binding
H7R41_RS10240	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
H7R41_RS10250	COG0583	DNA-binding transcription factor activity
H7R41_RS10260	COG2814	Major facilitator Superfamily
H7R41_RS10275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R41_RS10280	COG1346	cytolysis
H7R41_RS10290	COG0583	DNA-binding transcription factor activity
H7R41_RS10295	COG0625	glutathione transferase activity
H7R41_RS10300	COG0625	glutathione transferase activity
H7R41_RS10305	COG0583	DNA-binding transcription factor activity
H7R41_RS10320	COG1045	serine acetyltransferase
H7R41_RS10325	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H7R41_RS10330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H7R41_RS10355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R41_RS10360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H7R41_RS10370	COG0765	amino acid transport
H7R41_RS10375	COG0765	amino acid transport
H7R41_RS10395	COG2205	protein histidine kinase activity
H7R41_RS10395	COG0784	Response regulator, receiver
H7R41_RS10435	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS10485	COG0583	DNA-binding transcription factor activity
H7R41_RS10505	COG0318	PFAM AMP-dependent synthetase and ligase
H7R41_RS10510	COG1309	transcriptional regulator
H7R41_RS10515	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS10520	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H7R41_RS10525	COG1024	Enoyl-CoA hydratase
H7R41_RS10530	COG4770	biotin carboxylase activity
H7R41_RS10540	COG0583	DNA-binding transcription factor activity
H7R41_RS10555	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS10565	COG2814	Major facilitator Superfamily
H7R41_RS10575	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R41_RS10580	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
H7R41_RS10585	COG2814	Major facilitator Superfamily
H7R41_RS10590	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS10595	COG1024	Enoyl-CoA hydratase
H7R41_RS10600	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS10605	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R41_RS10610	COG0183	Belongs to the thiolase family
H7R41_RS10620	COG2814	Major facilitator Superfamily
H7R41_RS10630	COG1024	Enoyl-CoA hydratase
H7R41_RS10645	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS10650	COG2814	Major facilitator Superfamily
H7R41_RS10655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H7R41_RS10660	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
H7R41_RS10675	COG3842	ATPase activity
H7R41_RS10680	COG1840	ABC-type Fe3 transport system, periplasmic component
H7R41_RS10690	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R41_RS10695	COG1414	Transcriptional regulator
H7R41_RS10705	COG0583	DNA-binding transcription factor activity
H7R41_RS10710	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
H7R41_RS10715	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS10725	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
H7R41_RS10735	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS10740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R41_RS10745	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R41_RS10750	COG2267	carboxylic ester hydrolase activity
H7R41_RS10770	COG3038	cytochrome b561
H7R41_RS10775	COG0753	catalase activity
H7R41_RS10780	COG2271	Major facilitator Superfamily
H7R41_RS10785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7R41_RS10790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7R41_RS10840	COG2050	protein possibly involved in aromatic compounds catabolism
H7R41_RS10850	COG3327	negative regulation of DNA-templated transcription, initiation
H7R41_RS10855	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
H7R41_RS10860	COG0183	Belongs to the thiolase family
H7R41_RS10865	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R41_RS10870	COG1024	Enoyl-CoA hydratase
H7R41_RS10875	COG1024	Enoyl-CoA hydratase
H7R41_RS10880	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
H7R41_RS10885	COG2151	metal-sulfur cluster biosynthetic enzyme
H7R41_RS10890	COG3396	Phenylacetate-CoA oxygenase
H7R41_RS10895	COG3460	Phenylacetate-CoA oxygenase
H7R41_RS10900	COG3396	Phenylacetate-CoA oxygenase
H7R41_RS10905	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS10905	COG2030	dehydratase
H7R41_RS10910	COG1760	l-serine dehydratase
H7R41_RS10915	COG0531	amino acid
H7R41_RS10920	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS10945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
H7R41_RS10965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R41_RS10975	COG0789	Transcriptional regulator
H7R41_RS10985	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
H7R41_RS11000	COG2807	transmembrane transport
H7R41_RS11020	COG1063	alcohol dehydrogenase
H7R41_RS11030	COG1309	transcriptional regulator
H7R41_RS11040	COG0038	chloride channel
H7R41_RS11045	COG4770	biotin carboxylase activity
H7R41_RS11065	COG1914	H( )-stimulated, divalent metal cation uptake system
H7R41_RS11070	COG0583	DNA-binding transcription factor activity
H7R41_RS11085	COG1011	Hydrolase
H7R41_RS11105	COG1250	3-hydroxyacyl-CoA dehydrogenase
H7R41_RS11150	COG4521	taurine ABC transporter
H7R41_RS11155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R41_RS11160	COG1116	anion transmembrane transporter activity
H7R41_RS11165	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H7R41_RS11175	COG2814	Major facilitator Superfamily
H7R41_RS11185	COG1560	Kdo2-lipid A biosynthetic process
H7R41_RS11195	COG5006	permease, DMT superfamily
H7R41_RS11200	COG1522	sequence-specific DNA binding
H7R41_RS11215	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
H7R41_RS11225	COG4122	O-methyltransferase activity
H7R41_RS11255	COG1538	Outer membrane efflux protein
H7R41_RS11260	COG1137	ATPase activity
H7R41_RS11265	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
H7R41_RS11275	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
H7R41_RS11325	COG2814	Major facilitator Superfamily
H7R41_RS11360	COG1278	Cold shock
H7R41_RS11365	COG1280	lysine exporter protein (LysE YggA)
H7R41_RS11395	COG1570	exodeoxyribonuclease VII activity
H7R41_RS11445	COG0583	DNA-binding transcription factor activity
H7R41_RS11450	COG4638	Rieske (2fe-2S)
H7R41_RS11455	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
H7R41_RS11460	COG0633	Ferredoxin
H7R41_RS11460	COG0543	2 iron, 2 sulfur cluster binding
H7R41_RS11465	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS11470	COG3135	benzoate transporter
H7R41_RS11475	COG2814	Major facilitator Superfamily
H7R41_RS11490	COG1643	Atp-dependent helicase
H7R41_RS11495	COG0450	alkyl hydroperoxide reductase
H7R41_RS11505	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
H7R41_RS11515	COG3634	alkyl hydroperoxide reductase activity
H7R41_RS11535	COG0220	tRNA (guanine-N7-)-methyltransferase activity
H7R41_RS11540	COG0625	glutathione transferase activity
H7R41_RS11550	COG2885	chlorophyll binding
H7R41_RS11585	COG0542	response to heat
H7R41_RS11600	COG1765	OsmC-like protein
H7R41_RS11610	COG0667	Aldo Keto reductase
H7R41_RS11625	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
H7R41_RS11635	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
H7R41_RS11645	COG0527	aspartate kinase activity
H7R41_RS11655	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H7R41_RS11665	COG3038	cytochrome b561
H7R41_RS11670	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
H7R41_RS11675	COG2252	PERMEase
H7R41_RS11710	COG0531	amino acid
H7R41_RS11720	COG1113	amino acid transport
H7R41_RS11800	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H7R41_RS11810	COG1196	nuclear chromosome segregation
H7R41_RS11885	COG0431	NADPH-dependent FMN reductase
H7R41_RS11900	COG2207	Transcriptional regulator
H7R41_RS11905	COG1335	isochorismatase
H7R41_RS11955	COG1902	pentaerythritol trinitrate reductase activity
H7R41_RS11955	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R41_RS11965	COG3706	GGDEF domain
H7R41_RS11965	COG4251	negative regulation of phosphorylation
H7R41_RS11965	COG2203	Gaf domain
H7R41_RS11965	COG5001	Diguanylate cyclase
H7R41_RS11975	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R41_RS11995	COG4172	Belongs to the ABC transporter superfamily
H7R41_RS12000	COG4239	(ABC) transporter, permease
H7R41_RS12005	COG4174	ABC transporter (Permease)
H7R41_RS12015	COG1388	LysM domain
H7R41_RS12015	COG0741	lytic transglycosylase activity
H7R41_RS12015	COG1388	LysM domain
H7R41_RS12015	COG0741	lytic transglycosylase activity
H7R41_RS12020	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R41_RS12060	COG0583	DNA-binding transcription factor activity
H7R41_RS12065	COG1279	arginine transmembrane transporter activity
H7R41_RS12085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R41_RS12090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R41_RS12095	COG0006	proline dipeptidase activity
H7R41_RS12135	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
H7R41_RS12160	COG3384	dioxygenase
H7R41_RS12170	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H7R41_RS12175	COG2878	Part of a membrane complex involved in electron transport
H7R41_RS12180	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
H7R41_RS12205	COG0768	penicillin binding
H7R41_RS12210	COG0742	ribosomal rna small subunit methyltransferase
H7R41_RS12225	COG0830	nickel cation binding
H7R41_RS12235	COG0804	urea catabolic process
H7R41_RS12280	COG1253	flavin adenine dinucleotide binding
H7R41_RS12285	COG2851	Citrate transporter
H7R41_RS12335	COG1773	rubredoxin
H7R41_RS12340	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
H7R41_RS12350	COG0583	DNA-binding transcription factor activity
H7R41_RS12380	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
H7R41_RS12385	COG4181	ATPase activity
H7R41_RS12430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
H7R41_RS12450	COG0306	phosphate transporter
H7R41_RS12460	COG3958	Transketolase
H7R41_RS12465	COG3959	Transketolase, thiamine diphosphate binding domain
H7R41_RS12470	COG2271	Major facilitator Superfamily
H7R41_RS12475	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS12480	COG0583	DNA-binding transcription factor activity
H7R41_RS12500	COG2223	nitrite transmembrane transporter activity
H7R41_RS12505	COG2207	Transcriptional regulator
H7R41_RS12510	COG2066	Belongs to the glutaminase family
H7R41_RS12515	COG0242	peptide deformylase activity
H7R41_RS12520	COG0477	Major facilitator Superfamily
H7R41_RS12530	COG0028	Belongs to the TPP enzyme family
H7R41_RS12545	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS12550	COG2267	carboxylic ester hydrolase activity
H7R41_RS12560	COG2271	Major facilitator Superfamily
H7R41_RS12565	COG0446	pyridine nucleotide-disulphide oxidoreductase
H7R41_RS12575	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS12595	COG1414	Transcriptional regulator
H7R41_RS12610	COG1024	Enoyl-CoA hydratase
H7R41_RS12620	COG1215	transferase activity, transferring glycosyl groups
H7R41_RS12625	COG1649	PFAM Uncharacterised BCR, COG1649
H7R41_RS12625	COG0726	polysaccharide deacetylase
H7R41_RS12635	COG4681	YaeQ
H7R41_RS12645	COG0523	cobalamin synthesis protein
H7R41_RS12655	COG1607	acyl-coa hydrolase
H7R41_RS12665	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7R41_RS12670	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
H7R41_RS12675	COG1309	transcriptional regulator
H7R41_RS12700	COG2040	homocysteine
H7R41_RS12705	COG0531	amino acid
H7R41_RS12730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R41_RS12735	COG0477	Major facilitator Superfamily
H7R41_RS12770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H7R41_RS12885	COG4695	Portal protein
H7R41_RS12890	COG1802	Transcriptional regulator
H7R41_RS12890	COG4626	Terminase
H7R41_RS12985	COG0582	viral genome integration into host DNA
H7R41_RS12990	COG3177	Filamentation induced by cAMP protein fic
H7R41_RS12995	COG0583	DNA-binding transcription factor activity
H7R41_RS13000	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS13010	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
H7R41_RS13015	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7R41_RS13020	COG0583	DNA-binding transcription factor activity
H7R41_RS13030	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
H7R41_RS13035	COG2814	Major facilitator Superfamily
H7R41_RS13045	COG4829	muconolactone delta-isomerase
H7R41_RS13050	COG0427	acetyl-CoA hydrolase
H7R41_RS13055	COG0183	Belongs to the thiolase family
H7R41_RS13085	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
H7R41_RS13085	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
H7R41_RS13135	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
H7R41_RS13205	COG0582	viral genome integration into host DNA
H7R41_RS13215	COG0405	Gamma-glutamyltransferase
H7R41_RS13220	COG2814	Major facilitator Superfamily
H7R41_RS13230	COG2050	protein possibly involved in aromatic compounds catabolism
H7R41_RS13245	COG1090	epimerase
H7R41_RS13265	COG0420	3'-5' exonuclease activity
H7R41_RS13290	COG0735	belongs to the Fur family
H7R41_RS13295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H7R41_RS13315	COG0121	glutamine amidotransferase
H7R41_RS13330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7R41_RS13340	COG0210	DNA helicase
H7R41_RS13345	COG2885	chlorophyll binding
H7R41_RS13350	COG0204	Acyl-transferase
H7R41_RS13365	COG2894	cell division
H7R41_RS13380	COG1280	lysine exporter protein (LysE YggA)
H7R41_RS13385	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
H7R41_RS13385	COG1674	ftsk spoiiie
H7R41_RS13390	COG0492	ferredoxin-NADP+ reductase activity
H7R41_RS13395	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
H7R41_RS13405	COG0456	acetyltransferase
H7R41_RS13450	COG1981	membrane
H7R41_RS13465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
H7R41_RS13465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7R41_RS13485	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS13495	COG0657	acetylesterase activity
H7R41_RS13505	COG0473	3-isopropylmalate dehydrogenase activity
H7R41_RS13510	COG0583	DNA-binding transcription factor activity
H7R41_RS13530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R41_RS13555	COG0564	pseudouridine synthase activity
H7R41_RS13565	COG0358	DNA primase activity
H7R41_RS13580	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
H7R41_RS13610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
H7R41_RS13640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
H7R41_RS13650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
H7R41_RS13650	COG0352	thiamine-phosphate diphosphorylase activity
H7R41_RS13650	COG0351	phosphomethylpyrimidine kinase
H7R41_RS13655	COG1652	LysM domain
H7R41_RS13680	COG1399	metal-binding, possibly nucleic acid-binding protein
H7R41_RS13685	COG3101	peptidyl-lysine hydroxylation
H7R41_RS13690	COG0009	L-threonylcarbamoyladenylate synthase
H7R41_RS13695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H7R41_RS13700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H7R41_RS13715	COG4106	trans-aconitate 2-methyltransferase activity
H7R41_RS13730	COG2226	methyltransferase
H7R41_RS13730	COG0596	Alpha beta hydrolase
H7R41_RS13730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7R41_RS13735	COG1877	trehalose-phosphatase activity
H7R41_RS13740	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
H7R41_RS13745	COG2223	nitrite transmembrane transporter activity
H7R41_RS13765	COG1196	nuclear chromosome segregation
H7R41_RS13775	COG0730	response to heat
H7R41_RS13790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
H7R41_RS13800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7R41_RS13860	COG0489	protein tyrosine kinase activity
H7R41_RS13870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R41_RS13870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R41_RS13900	COG2515	1-aminocyclopropane-1-carboxylate deaminase
H7R41_RS13905	COG2081	HI0933 family
H7R41_RS13915	COG0668	transmembrane transport
H7R41_RS13935	COG0583	DNA-binding transcription factor activity
H7R41_RS13960	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
H7R41_RS13965	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7R41_RS13995	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H7R41_RS14035	COG0745	RESPONSE REGULATOR receiver
H7R41_RS14050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7R41_RS14095	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
H7R41_RS14155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
H7R41_RS14170	COG0583	DNA-binding transcription factor activity
H7R41_RS14200	COG0583	DNA-binding transcription factor activity
H7R41_RS14215	COG0583	DNA-binding transcription factor activity
H7R41_RS14220	COG1053	succinate dehydrogenase
H7R41_RS14230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
H7R41_RS14235	COG2814	Major facilitator Superfamily
H7R41_RS14240	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS14245	COG0583	DNA-binding transcription factor activity
H7R41_RS14250	COG1063	alcohol dehydrogenase
H7R41_RS14280	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H7R41_RS14285	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
H7R41_RS14290	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7R41_RS14310	COG2132	Multicopper oxidase
H7R41_RS14320	COG0561	phosphatase activity
H7R41_RS14325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H7R41_RS14350	COG1214	PFAM Peptidase M22, glycoprotease
H7R41_RS14400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
H7R41_RS14410	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
H7R41_RS14415	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
H7R41_RS14420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H7R41_RS14480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H7R41_RS14490	COG1846	Transcriptional regulator
H7R41_RS14495	COG1764	response to oxidative stress
H7R41_RS14535	COG0037	tRNA processing
H7R41_RS14545	COG0248	Ppx GppA phosphatase
H7R41_RS14575	COG0072	phenylalanine-tRNA ligase activity
H7R41_RS14615	COG1238	metal cluster binding
H7R41_RS14620	COG0625	glutathione transferase activity
H7R41_RS14635	COG0318	PFAM AMP-dependent synthetase and ligase
H7R41_RS14640	COG3028	Belongs to the UPF0307 family
H7R41_RS14645	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H7R41_RS14665	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H7R41_RS14670	COG0617	tRNA 3'-terminal CCA addition
H7R41_RS14675	COG1555	photosystem II stabilization
H7R41_RS14680	COG3956	TIGRFAM MazG family protein
H7R41_RS14690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H7R41_RS14710	COG0784	Response regulator, receiver
H7R41_RS14710	COG2205	protein histidine kinase activity
H7R41_RS14710	COG5002	protein histidine kinase activity
H7R41_RS14715	COG1024	Enoyl-CoA hydratase
H7R41_RS14720	COG2084	Dehydrogenase
H7R41_RS14725	COG3622	Belongs to the hyi family
H7R41_RS14755	COG0697	spore germination
H7R41_RS14765	COG2814	Major facilitator Superfamily
H7R41_RS14770	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
H7R41_RS14780	COG0583	DNA-binding transcription factor activity
H7R41_RS14790	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
H7R41_RS14800	COG0084	hydrolase, TatD family'
H7R41_RS14815	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
H7R41_RS14865	COG0440	acetolactate synthase activity
H7R41_RS14870	COG0028	Belongs to the TPP enzyme family
H7R41_RS14895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
H7R41_RS14900	COG1136	(ABC) transporter
H7R41_RS14900	COG0577	efflux transmembrane transporter activity
H7R41_RS14905	COG1538	Outer membrane efflux protein
H7R41_RS14920	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
H7R41_RS14925	COG1162	GTPase activity
H7R41_RS14935	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
H7R41_RS14955	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
H7R41_RS14960	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS15000	COG2986	histidine ammonia-lyase
H7R41_RS15010	COG1216	Glycosyl transferase, family 2
H7R41_RS15015	COG0318	PFAM AMP-dependent synthetase and ligase
H7R41_RS15025	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7R41_RS15070	COG1426	Protein conserved in bacteria
H7R41_RS15105	COG0793	Belongs to the peptidase S41A family
H7R41_RS15120	COG2267	carboxylic ester hydrolase activity
H7R41_RS15130	COG1012	belongs to the aldehyde dehydrogenase family
H7R41_RS15135	COG3265	gluconokinase activity
H7R41_RS15145	COG0800	Aldolase
H7R41_RS15155	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H7R41_RS15160	COG0857	belongs to the CobB CobQ family
H7R41_RS15160	COG0280	phosphate acetyltransferase
H7R41_RS15165	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
H7R41_RS15165	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
H7R41_RS15185	COG0740	serine-type endopeptidase activity
H7R41_RS15195	COG4774	siderophore transport
H7R41_RS15205	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
H7R41_RS15215	COG2813	Specifically methylates the guanine in position
H7R41_RS15215	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
H7R41_RS15315	COG0788	formyltetrahydrofolate deformylase activity
H7R41_RS15340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7R41_RS15340	COG4651	solute:proton antiporter activity
H7R41_RS15360	COG0724	RNA recognition motif
H7R41_RS15365	COG0210	DNA helicase
H7R41_RS15390	COG1733	regulation of RNA biosynthetic process
H7R41_RS15400	COG2900	Belongs to the SlyX family
H7R41_RS15405	COG0488	(ABC) transporter
H7R41_RS15410	COG1280	lysine exporter protein (LysE YggA)
H7R41_RS15415	COG1560	Kdo2-lipid A biosynthetic process
H7R41_RS15425	COG1301	dicarboxylic acid transport
H7R41_RS15480	COG0473	3-isopropylmalate dehydrogenase activity
H7R41_RS15535	COG0583	DNA-binding transcription factor activity
H7R41_RS15545	COG0625	glutathione transferase activity
H7R41_RS15550	COG2378	regulation of single-species biofilm formation
H7R41_RS15555	COG0546	phosphoglycolate phosphatase activity
H7R41_RS15565	COG1530	ribonuclease E activity
H7R41_RS15570	COG0318	PFAM AMP-dependent synthetase and ligase
H7R41_RS15585	COG0583	DNA-binding transcription factor activity
H7R41_RS15590	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS15595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
H7R41_RS15605	COG0534	Mate efflux family protein
H7R41_RS15620	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
H7R41_RS15645	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
H7R41_RS15645	COG0493	'glutamate synthase
H7R41_RS15655	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
H7R41_RS15660	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
H7R41_RS15675	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
H7R41_RS15685	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
H7R41_RS15685	COG0644	oxidoreductase
H7R41_RS15695	COG0425	Belongs to the sulfur carrier protein TusA family
H7R41_RS15700	COG4535	Mg2 and Co2 transporter CorC
H7R41_RS15710	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
H7R41_RS15730	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H7R41_RS15735	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
H7R41_RS15735	COG0475	glutathione-regulated potassium exporter activity
H7R41_RS15750	COG0484	heat shock protein binding
H7R41_RS15755	COG0789	Transcriptional regulator
H7R41_RS15760	COG0598	Magnesium transport protein CorA
H7R41_RS15775	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
H7R41_RS15780	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H7R41_RS15785	COG1074	ATP-dependent DNA helicase activity
H7R41_RS15790	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
H7R41_RS15810	COG2226	methyltransferase
H7R41_RS15825	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
H7R41_RS15830	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
H7R41_RS15845	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
H7R41_RS15845	COG2111	Na H antiporter
H7R41_RS15850	COG1006	Multisubunit Na H antiporter MnhC subunit
H7R41_RS15855	COG0651	ATP synthesis coupled electron transport
H7R41_RS15860	COG1863	multisubunit Na H antiporter MnhE subunit
H7R41_RS15865	COG2212	antiporter activity
H7R41_RS15870	COG1320	monovalent cation:proton antiporter activity
H7R41_RS15885	COG0195	Participates in both transcription termination and antitermination
H7R41_RS15935	COG0237	dephospho-CoA kinase activity
H7R41_RS15945	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H7R41_RS15960	COG0497	DNA recombination
H7R41_RS15970	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
H7R41_RS16000	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H7R41_RS16000	COG2169	Transcriptional regulator
H7R41_RS16005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H7R41_RS16065	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
H7R41_RS16080	COG0326	Molecular chaperone. Has ATPase activity
H7R41_RS16095	COG2056	Na+-H+ antiporter family
H7R41_RS16100	COG0596	Alpha beta hydrolase
H7R41_RS16195	COG0546	phosphoglycolate phosphatase activity
H7R41_RS16200	COG1716	ATPase activity
H7R41_RS16245	COG0181	hydroxymethylbilane synthase activity
H7R41_RS16255	COG3275	phosphorelay sensor kinase activity
H7R41_RS16275	COG1538	Outer membrane efflux protein
H7R41_RS16280	COG0697	spore germination
H7R41_RS16305	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
H7R41_RS16310	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
H7R41_RS16315	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
H7R41_RS16320	COG0772	Belongs to the SEDS family
H7R41_RS16345	COG4974	Belongs to the 'phage' integrase family
H7R41_RS16350	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R41_RS16360	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
H7R41_RS16370	COG2197	response regulator
H7R41_RS16385	COG0793	Belongs to the peptidase S41A family
H7R41_RS16390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
H7R41_RS16395	COG0795	lipopolysaccharide-transporting ATPase activity
H7R41_RS16435	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7R41_RS16435	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
H7R41_RS16445	COG0004	ammonium transporteR
H7R41_RS16450	COG0347	Belongs to the P(II) protein family
H7R41_RS16460	COG0606	chelatase, subunit chli
H7R41_RS16465	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H7R41_RS16475	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
H7R41_RS16490	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H7R41_RS16505	COG0318	PFAM AMP-dependent synthetase and ligase
H7R41_RS16515	COG0477	Major facilitator Superfamily
H7R41_RS16520	COG2860	membrane
H7R41_RS16525	COG3012	SEC-C Motif Domain Protein
H7R41_RS16530	COG1253	flavin adenine dinucleotide binding
H7R41_RS16540	COG0477	Major facilitator Superfamily
H7R41_RS16585	COG0655	NAD(P)H dehydrogenase (quinone) activity
H7R41_RS16595	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
H7R41_RS16630	COG1309	transcriptional regulator
H7R41_RS16665	COG0697	spore germination
H7R41_RS16670	COG1309	transcriptional regulator
H7R41_RS16685	COG0386	Belongs to the glutathione peroxidase family
H7R41_RS16755	COG1121	(ABC) transporter
H7R41_RS16760	COG1108	ABC-type Mn2 Zn2 transport systems permease components
H7R41_RS16765	COG1280	lysine exporter protein (LysE YggA)
H7R41_RS16770	COG2837	iron assimilation
H7R41_RS16775	COG0281	malic enzyme
H7R41_RS16820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
H7R41_RS16820	COG0519	Catalyzes the synthesis of GMP from XMP
H7R41_RS16825	COG4399	Belongs to the UPF0754 family
H7R41_RS16830	COG2259	Doxx family
H7R41_RS16835	COG0586	Pfam SNARE associated Golgi protein
H7R41_RS16850	COG1192	Involved in chromosome partitioning
H7R41_RS16860	COG0271	Belongs to the BolA IbaG family
H7R41_RS16900	COG3321	synthase
H7R41_RS16900	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
H7R41_RS16900	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
H7R41_RS16900	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
H7R41_RS16905	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS16915	COG2197	response regulator
H7R41_RS16925	COG3916	Acyl-homoserine-lactone synthase
H7R41_RS16930	COG0477	Major facilitator Superfamily
H7R41_RS16935	COG1024	Enoyl-CoA hydratase
H7R41_RS16940	COG1024	Enoyl-CoA hydratase
H7R41_RS16945	COG1960	acyl-CoA dehydrogenase activity
H7R41_RS16950	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
H7R41_RS16970	COG1113	amino acid transport
H7R41_RS16975	COG1113	amino acid transport
H7R41_RS16980	COG0251	oxidation-reduction process
H7R41_RS17020	COG0564	pseudouridine synthase activity
H7R41_RS17065	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
H7R41_RS17080	COG1802	Transcriptional regulator
H7R41_RS17090	COG1448	Aminotransferase
H7R41_RS17095	COG0277	FAD linked oxidase domain protein
H7R41_RS17105	COG2186	Transcriptional regulator
H7R41_RS17115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
H7R41_RS17120	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H7R41_RS17125	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H7R41_RS17140	COG1210	Utp--glucose-1-phosphate uridylyltransferase
H7R41_RS17145	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
H7R41_RS17150	COG1216	Glycosyl transferase, family 2
H7R41_RS17155	COG0438	transferase activity, transferring glycosyl groups
H7R41_RS17200	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
H7R41_RS17230	COG0728	peptidoglycan biosynthetic process
H7R41_RS17235	COG3023	N-Acetylmuramoyl-L-alanine amidase
H7R41_RS17290	COG0546	phosphoglycolate phosphatase activity
H7R41_RS17295	COG1028	Short-chain dehydrogenase reductase Sdr
H7R41_RS17315	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R41_RS17320	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
H7R41_RS17325	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
H7R41_RS17330	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H7R41_RS17335	COG1116	anion transmembrane transporter activity
H7R41_RS17340	COG1309	transcriptional regulator
H7R41_RS17345	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H7R41_RS17355	COG0196	riboflavin kinase activity
H7R41_RS17360	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
H7R41_RS17370	COG1047	Peptidyl-prolyl cis-trans
H7R41_RS17410	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
H7R41_RS17415	COG0657	acetylesterase activity
H7R41_RS17465	COG2951	lytic endotransglycosylase activity
H7R41_RS17470	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H7R41_RS17485	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
H7R41_RS17495	COG0671	phosphoesterase, PA-phosphatase related
H7R41_RS17500	COG0861	Integral membrane protein TerC family
H7R41_RS17510	COG0754	glutathionylspermidine amidase activity
H7R41_RS17520	COG0402	S-adenosylhomocysteine deaminase activity
H7R41_RS17535	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
H7R41_RS17540	COG1230	cation diffusion facilitator family transporter
H7R41_RS17555	COG0706	membrane insertase activity
H7R41_RS17605	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
H7R41_RS17625	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
H7R41_RS17805	COG0358	DNA primase activity
H7R41_RS17865	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
H7R41_RS17910	COG0587	DNA-directed DNA polymerase activity
H7R41_RS17925	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7R41_RS17925	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
H7R41_RS17975	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H7R41_RS17975	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7R41_RS17980	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H7R41_RS18025	COG2194	sulfuric ester hydrolase activity
H7R41_RS18045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H7R41_RS18110	COG3328	transposase activity
H7R41_RS18135	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
H7R41_RS18190	COG0753	catalase activity
H7R41_RS18240	COG0627	Serine hydrolase involved in the detoxification of formaldehyde