locus-tag	class	description
GFM36_RS00010	COG0592	DNA-directed DNA polymerase activity
GFM36_RS00020	COG0187	DNA topoisomerase II activity
GFM36_RS00030	COG0586	Pfam SNARE associated Golgi protein
GFM36_RS00035	COG0488	(ABC) transporter
GFM36_RS00060	COG0596	Alpha beta hydrolase
GFM36_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
GFM36_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GFM36_RS00110	COG1047	Peptidyl-prolyl cis-trans
GFM36_RS00120	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GFM36_RS00125	COG0196	riboflavin kinase activity
GFM36_RS00135	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GFM36_RS00140	COG1309	transcriptional regulator
GFM36_RS00145	COG1116	anion transmembrane transporter activity
GFM36_RS00150	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFM36_RS00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFM36_RS00160	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFM36_RS00165	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFM36_RS00185	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS00190	COG0546	phosphoglycolate phosphatase activity
GFM36_RS00245	COG3023	N-Acetylmuramoyl-L-alanine amidase
GFM36_RS00250	COG0728	peptidoglycan biosynthetic process
GFM36_RS00280	COG1596	polysaccharide export
GFM36_RS00285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GFM36_RS00295	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GFM36_RS00300	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GFM36_RS00305	COG2089	acid synthase
GFM36_RS00315	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GFM36_RS00320	COG1083	cytidylyl-transferase
GFM36_RS00325	COG2244	polysaccharide biosynthetic process
GFM36_RS00365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GFM36_RS00370	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GFM36_RS00375	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GFM36_RS00390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GFM36_RS00395	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFM36_RS00405	COG2186	Transcriptional regulator
GFM36_RS00415	COG0277	FAD linked oxidase domain protein
GFM36_RS00420	COG1448	Aminotransferase
GFM36_RS00430	COG1802	Transcriptional regulator
GFM36_RS00445	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GFM36_RS00470	COG0564	pseudouridine synthase activity
GFM36_RS00510	COG0251	oxidation-reduction process
GFM36_RS00515	COG1113	amino acid transport
GFM36_RS00520	COG1113	amino acid transport
GFM36_RS00540	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFM36_RS00545	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS00550	COG1024	Enoyl-CoA hydratase
GFM36_RS00555	COG1024	Enoyl-CoA hydratase
GFM36_RS00560	COG0477	Major facilitator Superfamily
GFM36_RS00565	COG3916	Acyl-homoserine-lactone synthase
GFM36_RS00575	COG2197	response regulator
GFM36_RS00585	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS00590	COG3321	synthase
GFM36_RS00590	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
GFM36_RS00590	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GFM36_RS00590	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GFM36_RS00630	COG0271	Belongs to the BolA IbaG family
GFM36_RS00640	COG1192	Involved in chromosome partitioning
GFM36_RS00655	COG0586	Pfam SNARE associated Golgi protein
GFM36_RS00660	COG2259	Doxx family
GFM36_RS00665	COG4399	Belongs to the UPF0754 family
GFM36_RS00670	COG0519	Catalyzes the synthesis of GMP from XMP
GFM36_RS00670	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GFM36_RS00715	COG0281	malic enzyme
GFM36_RS00725	COG2837	iron assimilation
GFM36_RS00730	COG1280	lysine exporter protein (LysE YggA)
GFM36_RS00735	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GFM36_RS00740	COG1121	(ABC) transporter
GFM36_RS00810	COG0386	Belongs to the glutathione peroxidase family
GFM36_RS00825	COG1309	transcriptional regulator
GFM36_RS00830	COG0697	spore germination
GFM36_RS00840	COG0758	DNA mediated transformation
GFM36_RS00910	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
GFM36_RS00920	COG0655	NAD(P)H dehydrogenase (quinone) activity
GFM36_RS00960	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFM36_RS00970	COG2814	Major facilitator Superfamily
GFM36_RS00980	COG1253	flavin adenine dinucleotide binding
GFM36_RS00985	COG3012	SEC-C Motif Domain Protein
GFM36_RS00990	COG2860	membrane
GFM36_RS00995	COG0477	Major facilitator Superfamily
GFM36_RS01005	COG0318	PFAM AMP-dependent synthetase and ligase
GFM36_RS01020	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GFM36_RS01040	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFM36_RS01045	COG0235	Class ii aldolase
GFM36_RS01105	COG5002	protein histidine kinase activity
GFM36_RS01125	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFM36_RS01155	COG0347	Belongs to the P(II) protein family
GFM36_RS01160	COG0004	ammonium transporteR
GFM36_RS01170	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFM36_RS01170	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GFM36_RS01210	COG0795	lipopolysaccharide-transporting ATPase activity
GFM36_RS01215	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GFM36_RS01220	COG0793	Belongs to the peptidase S41A family
GFM36_RS01235	COG2197	response regulator
GFM36_RS01245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GFM36_RS01255	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GFM36_RS01260	COG4974	Belongs to the 'phage' integrase family
GFM36_RS01285	COG0772	Belongs to the SEDS family
GFM36_RS01290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFM36_RS01295	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GFM36_RS01300	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GFM36_RS01325	COG0697	spore germination
GFM36_RS01335	COG1538	Outer membrane efflux protein
GFM36_RS01355	COG3275	phosphorelay sensor kinase activity
GFM36_RS01365	COG0181	hydroxymethylbilane synthase activity
GFM36_RS01415	COG1716	ATPase activity
GFM36_RS01420	COG0546	phosphoglycolate phosphatase activity
GFM36_RS01515	COG0596	Alpha beta hydrolase
GFM36_RS01520	COG2056	Na+-H+ antiporter family
GFM36_RS01535	COG0326	Molecular chaperone. Has ATPase activity
GFM36_RS01550	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GFM36_RS01610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFM36_RS01615	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFM36_RS01615	COG2169	Transcriptional regulator
GFM36_RS01645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GFM36_RS01655	COG0497	DNA recombination
GFM36_RS01670	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFM36_RS01680	COG0237	dephospho-CoA kinase activity
GFM36_RS01685	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
GFM36_RS01735	COG0195	Participates in both transcription termination and antitermination
GFM36_RS01750	COG1320	monovalent cation:proton antiporter activity
GFM36_RS01755	COG2212	antiporter activity
GFM36_RS01760	COG1863	multisubunit Na H antiporter MnhE subunit
GFM36_RS01765	COG0651	ATP synthesis coupled electron transport
GFM36_RS01770	COG1006	Multisubunit Na H antiporter MnhC subunit
GFM36_RS01775	COG2111	Na H antiporter
GFM36_RS01775	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GFM36_RS01790	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GFM36_RS01795	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFM36_RS01810	COG2226	methyltransferase
GFM36_RS01830	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GFM36_RS01835	COG1074	ATP-dependent DNA helicase activity
GFM36_RS01840	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GFM36_RS01845	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFM36_RS01860	COG0598	Magnesium transport protein CorA
GFM36_RS01865	COG0789	Transcriptional regulator
GFM36_RS01870	COG0484	heat shock protein binding
GFM36_RS01885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFM36_RS01885	COG0475	glutathione-regulated potassium exporter activity
GFM36_RS01890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GFM36_RS01910	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFM36_RS01920	COG4535	Mg2 and Co2 transporter CorC
GFM36_RS01925	COG0425	Belongs to the sulfur carrier protein TusA family
GFM36_RS01935	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
GFM36_RS01935	COG0644	oxidoreductase
GFM36_RS01945	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GFM36_RS01960	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFM36_RS01965	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
GFM36_RS01975	COG0493	'glutamate synthase
GFM36_RS01975	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
GFM36_RS02005	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GFM36_RS02020	COG0534	Mate efflux family protein
GFM36_RS02030	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GFM36_RS02035	COG4221	oxidoreductase activity
GFM36_RS02040	COG0583	DNA-binding transcription factor activity
GFM36_RS02055	COG0318	PFAM AMP-dependent synthetase and ligase
GFM36_RS02060	COG1530	ribonuclease E activity
GFM36_RS02070	COG0546	phosphoglycolate phosphatase activity
GFM36_RS02075	COG2378	regulation of single-species biofilm formation
GFM36_RS02080	COG0625	glutathione transferase activity
GFM36_RS02090	COG0583	DNA-binding transcription factor activity
GFM36_RS02155	COG0473	3-isopropylmalate dehydrogenase activity
GFM36_RS02210	COG1301	dicarboxylic acid transport
GFM36_RS02220	COG1560	Kdo2-lipid A biosynthetic process
GFM36_RS02225	COG1280	lysine exporter protein (LysE YggA)
GFM36_RS02230	COG0488	(ABC) transporter
GFM36_RS02235	COG2900	Belongs to the SlyX family
GFM36_RS02245	COG1733	regulation of RNA biosynthetic process
GFM36_RS02270	COG0210	DNA helicase
GFM36_RS02275	COG0724	RNA recognition motif
GFM36_RS02295	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GFM36_RS02295	COG4651	solute:proton antiporter activity
GFM36_RS02320	COG0788	formyltetrahydrofolate deformylase activity
GFM36_RS02425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFM36_RS02425	COG2813	Specifically methylates the guanine in position
GFM36_RS02435	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFM36_RS02445	COG4774	siderophore transport
GFM36_RS02455	COG0740	serine-type endopeptidase activity
GFM36_RS02475	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GFM36_RS02475	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GFM36_RS02480	COG0857	belongs to the CobB CobQ family
GFM36_RS02480	COG0280	phosphate acetyltransferase
GFM36_RS02485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GFM36_RS02495	COG0800	Aldolase
GFM36_RS02505	COG3265	gluconokinase activity
GFM36_RS02510	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS02520	COG2267	carboxylic ester hydrolase activity
GFM36_RS02535	COG0793	Belongs to the peptidase S41A family
GFM36_RS02570	COG1426	Protein conserved in bacteria
GFM36_RS02610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
GFM36_RS02620	COG1162	GTPase activity
GFM36_RS02625	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GFM36_RS02640	COG1538	Outer membrane efflux protein
GFM36_RS02645	COG1136	(ABC) transporter
GFM36_RS02645	COG0577	efflux transmembrane transporter activity
GFM36_RS02650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFM36_RS02675	COG0028	Belongs to the TPP enzyme family
GFM36_RS02680	COG0440	acetolactate synthase activity
GFM36_RS02780	COG0084	hydrolase, TatD family'
GFM36_RS02785	COG1002	Type II restriction enzyme, methylase subunits
GFM36_RS02790	COG1061	Type III restriction enzyme res subunit
GFM36_RS02800	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GFM36_RS02825	COG1401	restriction endodeoxyribonuclease activity
GFM36_RS02835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GFM36_RS02850	COG0084	hydrolase, TatD family'
GFM36_RS02860	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
GFM36_RS02870	COG0583	DNA-binding transcription factor activity
GFM36_RS02880	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFM36_RS02965	COG2205	protein histidine kinase activity
GFM36_RS02980	COG2132	Multicopper oxidase
GFM36_RS03005	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFM36_RS03040	COG0640	Transcriptional regulator
GFM36_RS03050	COG0798	PFAM Bile acid sodium symporter
GFM36_RS03055	COG0431	NADPH-dependent FMN reductase
GFM36_RS03060	COG0492	ferredoxin-NADP+ reductase activity
GFM36_RS03065	COG2072	flavoprotein involved in K transport
GFM36_RS03080	COG2814	Major facilitator Superfamily
GFM36_RS03090	COG0697	spore germination
GFM36_RS03120	COG3622	Belongs to the hyi family
GFM36_RS03125	COG2084	Dehydrogenase
GFM36_RS03130	COG1024	Enoyl-CoA hydratase
GFM36_RS03135	COG5002	protein histidine kinase activity
GFM36_RS03135	COG2205	protein histidine kinase activity
GFM36_RS03135	COG0784	Response regulator, receiver
GFM36_RS03155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFM36_RS03165	COG3956	TIGRFAM MazG family protein
GFM36_RS03170	COG1555	photosystem II stabilization
GFM36_RS03175	COG0617	tRNA 3'-terminal CCA addition
GFM36_RS03180	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GFM36_RS03200	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFM36_RS03205	COG3028	Belongs to the UPF0307 family
GFM36_RS03210	COG0318	PFAM AMP-dependent synthetase and ligase
GFM36_RS03225	COG0625	glutathione transferase activity
GFM36_RS03230	COG1238	metal cluster binding
GFM36_RS03275	COG0072	phenylalanine-tRNA ligase activity
GFM36_RS03305	COG0248	Ppx GppA phosphatase
GFM36_RS03315	COG0037	tRNA processing
GFM36_RS03355	COG1764	response to oxidative stress
GFM36_RS03360	COG1846	Transcriptional regulator
GFM36_RS03370	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFM36_RS03430	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFM36_RS03435	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GFM36_RS03440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GFM36_RS03450	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GFM36_RS03510	COG1214	PFAM Peptidase M22, glycoprotease
GFM36_RS03525	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GFM36_RS03535	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GFM36_RS03540	COG0561	phosphatase activity
GFM36_RS03550	COG2132	Multicopper oxidase
GFM36_RS03555	COG3667	copper resistance
GFM36_RS03570	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFM36_RS03575	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GFM36_RS03580	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GFM36_RS03610	COG1063	alcohol dehydrogenase
GFM36_RS03615	COG0583	DNA-binding transcription factor activity
GFM36_RS03620	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS03625	COG2814	Major facilitator Superfamily
GFM36_RS03630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFM36_RS03640	COG1053	succinate dehydrogenase
GFM36_RS03645	COG0583	DNA-binding transcription factor activity
GFM36_RS03660	COG0583	DNA-binding transcription factor activity
GFM36_RS03690	COG0583	DNA-binding transcription factor activity
GFM36_RS03705	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFM36_RS03745	COG0384	phenazine biosynthesis protein PhzF
GFM36_RS03760	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFM36_RS03780	COG0745	RESPONSE REGULATOR receiver
GFM36_RS03820	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GFM36_RS03850	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GFM36_RS03855	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GFM36_RS03875	COG0583	DNA-binding transcription factor activity
GFM36_RS03895	COG0668	transmembrane transport
GFM36_RS03905	COG2081	HI0933 family
GFM36_RS03910	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GFM36_RS03940	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFM36_RS03940	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GFM36_RS03950	COG0489	protein tyrosine kinase activity
GFM36_RS04010	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
GFM36_RS04020	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GFM36_RS04035	COG0730	response to heat
GFM36_RS04045	COG1196	nuclear chromosome segregation
GFM36_RS04065	COG2223	nitrite transmembrane transporter activity
GFM36_RS04070	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GFM36_RS04075	COG1877	trehalose-phosphatase activity
GFM36_RS04080	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFM36_RS04080	COG2226	methyltransferase
GFM36_RS04080	COG0596	Alpha beta hydrolase
GFM36_RS04095	COG4106	trans-aconitate 2-methyltransferase activity
GFM36_RS04110	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GFM36_RS04115	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GFM36_RS04120	COG0009	L-threonylcarbamoyladenylate synthase
GFM36_RS04125	COG3101	peptidyl-lysine hydroxylation
GFM36_RS04130	COG1399	metal-binding, possibly nucleic acid-binding protein
GFM36_RS04155	COG1652	LysM domain
GFM36_RS04160	COG0351	phosphomethylpyrimidine kinase
GFM36_RS04160	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GFM36_RS04160	COG0352	thiamine-phosphate diphosphorylase activity
GFM36_RS04170	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GFM36_RS04200	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFM36_RS04230	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
GFM36_RS04245	COG0358	DNA primase activity
GFM36_RS04255	COG0564	pseudouridine synthase activity
GFM36_RS04280	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GFM36_RS04300	COG0583	DNA-binding transcription factor activity
GFM36_RS04305	COG0473	3-isopropylmalate dehydrogenase activity
GFM36_RS04315	COG0657	acetylesterase activity
GFM36_RS04325	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS04345	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFM36_RS04345	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GFM36_RS04360	COG1981	membrane
GFM36_RS04405	COG0456	acetyltransferase
GFM36_RS04415	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GFM36_RS04420	COG0492	ferredoxin-NADP+ reductase activity
GFM36_RS04425	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
GFM36_RS04425	COG1674	ftsk spoiiie
GFM36_RS04430	COG1280	lysine exporter protein (LysE YggA)
GFM36_RS04445	COG2894	cell division
GFM36_RS04460	COG0204	Acyl-transferase
GFM36_RS04465	COG2885	chlorophyll binding
GFM36_RS04470	COG0210	DNA helicase
GFM36_RS04480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFM36_RS04495	COG0121	glutamine amidotransferase
GFM36_RS04515	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFM36_RS04520	COG0735	belongs to the Fur family
GFM36_RS04545	COG0420	3'-5' exonuclease activity
GFM36_RS04565	COG1090	epimerase
GFM36_RS04580	COG2050	protein possibly involved in aromatic compounds catabolism
GFM36_RS04590	COG2814	Major facilitator Superfamily
GFM36_RS04595	COG0405	Gamma-glutamyltransferase
GFM36_RS04670	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GFM36_RS04765	COG1484	DNA-dependent DNA replication
GFM36_RS04810	COG3755	Protein conserved in bacteria
GFM36_RS04960	COG2026	Addiction module toxin, RelE StbE family
GFM36_RS05000	COG0592	DNA-directed DNA polymerase activity
GFM36_RS05090	COG1061	Type III restriction enzyme res subunit
GFM36_RS05100	COG1192	Involved in chromosome partitioning
GFM36_RS05105	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GFM36_RS05115	COG1061	Type III restriction enzyme res subunit
GFM36_RS05145	COG0582	viral genome integration into host DNA
GFM36_RS05200	COG1733	regulation of RNA biosynthetic process
GFM36_RS05205	COG2814	Major facilitator Superfamily
GFM36_RS05210	COG0156	8-amino-7-oxononanoate synthase activity
GFM36_RS05225	COG0367	asparagine synthase
GFM36_RS05245	COG0477	Major facilitator Superfamily
GFM36_RS05250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFM36_RS05260	COG1595	DNA-templated transcription, initiation
GFM36_RS05315	COG0531	amino acid
GFM36_RS05320	COG2040	homocysteine
GFM36_RS05345	COG1309	transcriptional regulator
GFM36_RS05350	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFM36_RS05355	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFM36_RS05365	COG1607	acyl-coa hydrolase
GFM36_RS05375	COG0523	cobalamin synthesis protein
GFM36_RS05385	COG4681	YaeQ
GFM36_RS05395	COG1649	PFAM Uncharacterised BCR, COG1649
GFM36_RS05395	COG0726	polysaccharide deacetylase
GFM36_RS05400	COG1215	transferase activity, transferring glycosyl groups
GFM36_RS05410	COG1024	Enoyl-CoA hydratase
GFM36_RS05425	COG1414	Transcriptional regulator
GFM36_RS05445	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS05460	COG2271	Major facilitator Superfamily
GFM36_RS05470	COG2267	carboxylic ester hydrolase activity
GFM36_RS05475	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS05490	COG0028	Belongs to the TPP enzyme family
GFM36_RS05500	COG0477	Major facilitator Superfamily
GFM36_RS05505	COG0242	peptide deformylase activity
GFM36_RS05510	COG2066	Belongs to the glutaminase family
GFM36_RS05515	COG2207	Transcriptional regulator
GFM36_RS05520	COG2223	nitrite transmembrane transporter activity
GFM36_RS05545	COG0306	phosphate transporter
GFM36_RS05565	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GFM36_RS05610	COG4181	ATPase activity
GFM36_RS05615	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
GFM36_RS05645	COG0583	DNA-binding transcription factor activity
GFM36_RS05655	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFM36_RS05660	COG1773	rubredoxin
GFM36_RS05710	COG2851	Citrate transporter
GFM36_RS05715	COG1253	flavin adenine dinucleotide binding
GFM36_RS05755	COG0804	urea catabolic process
GFM36_RS05765	COG0830	nickel cation binding
GFM36_RS05780	COG0742	ribosomal rna small subunit methyltransferase
GFM36_RS05785	COG0768	penicillin binding
GFM36_RS05810	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GFM36_RS05815	COG2878	Part of a membrane complex involved in electron transport
GFM36_RS05820	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GFM36_RS05830	COG3384	dioxygenase
GFM36_RS05855	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GFM36_RS06180	COG0739	heme binding
GFM36_RS06225	COG2194	sulfuric ester hydrolase activity
GFM36_RS06265	COG0006	proline dipeptidase activity
GFM36_RS06270	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFM36_RS06275	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFM36_RS06295	COG1279	arginine transmembrane transporter activity
GFM36_RS06300	COG0583	DNA-binding transcription factor activity
GFM36_RS06340	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GFM36_RS06345	COG0741	lytic transglycosylase activity
GFM36_RS06345	COG1388	LysM domain
GFM36_RS06355	COG4174	ABC transporter (Permease)
GFM36_RS06360	COG4239	(ABC) transporter, permease
GFM36_RS06365	COG4172	Belongs to the ABC transporter superfamily
GFM36_RS06385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GFM36_RS06395	COG2203	Gaf domain
GFM36_RS06395	COG3706	GGDEF domain
GFM36_RS06395	COG5001	Diguanylate cyclase
GFM36_RS06395	COG4251	negative regulation of phosphorylation
GFM36_RS06405	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFM36_RS06405	COG1902	pentaerythritol trinitrate reductase activity
GFM36_RS06450	COG3152	Membrane
GFM36_RS06480	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GFM36_RS06485	COG0732	type I restriction modification DNA specificity domain
GFM36_RS06510	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GFM36_RS06520	COG0582	viral genome integration into host DNA
GFM36_RS06530	COG4269	membrane
GFM36_RS06575	COG1113	amino acid transport
GFM36_RS06585	COG0531	amino acid
GFM36_RS06605	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS06625	COG1113	amino acid transport
GFM36_RS06630	COG2831	hemolysin activation secretion protein
GFM36_RS06635	COG3210	domain, Protein
GFM36_RS06665	COG0697	spore germination
GFM36_RS06670	COG2721	sulfolactate sulfo-lyase activity
GFM36_RS06675	COG2271	Major facilitator Superfamily
GFM36_RS06680	COG4948	Mandelate Racemase Muconate Lactonizing
GFM36_RS06690	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS06695	COG2186	Transcriptional regulator
GFM36_RS06720	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS06730	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS06735	COG1024	Enoyl-CoA hydratase
GFM36_RS06740	COG2814	Major facilitator Superfamily
GFM36_RS06755	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFM36_RS06770	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GFM36_RS06815	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
GFM36_RS06820	COG2072	flavoprotein involved in K transport
GFM36_RS06825	COG0300	oxidoreductase activity
GFM36_RS06835	COG1309	transcriptional regulator
GFM36_RS06840	COG1741	Belongs to the pirin family
GFM36_RS06855	COG2072	flavoprotein involved in K transport
GFM36_RS06865	COG2252	PERMEase
GFM36_RS06870	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GFM36_RS06875	COG3038	cytochrome b561
GFM36_RS06885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFM36_RS06895	COG0527	aspartate kinase activity
GFM36_RS06905	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GFM36_RS06915	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GFM36_RS06930	COG0667	Aldo Keto reductase
GFM36_RS06945	COG1765	OsmC-like protein
GFM36_RS06960	COG0542	response to heat
GFM36_RS06995	COG2885	chlorophyll binding
GFM36_RS07005	COG0625	glutathione transferase activity
GFM36_RS07010	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GFM36_RS07030	COG3634	alkyl hydroperoxide reductase activity
GFM36_RS07040	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GFM36_RS07050	COG0450	alkyl hydroperoxide reductase
GFM36_RS07055	COG1643	Atp-dependent helicase
GFM36_RS07070	COG2814	Major facilitator Superfamily
GFM36_RS07075	COG3135	benzoate transporter
GFM36_RS07080	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS07085	COG0633	Ferredoxin
GFM36_RS07085	COG0543	2 iron, 2 sulfur cluster binding
GFM36_RS07095	COG4638	Rieske (2fe-2S)
GFM36_RS07100	COG0583	DNA-binding transcription factor activity
GFM36_RS07150	COG1570	exodeoxyribonuclease VII activity
GFM36_RS07180	COG1280	lysine exporter protein (LysE YggA)
GFM36_RS07185	COG1278	Cold shock
GFM36_RS07220	COG2814	Major facilitator Superfamily
GFM36_RS07270	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
GFM36_RS07280	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
GFM36_RS07285	COG1137	ATPase activity
GFM36_RS07290	COG1538	Outer membrane efflux protein
GFM36_RS07320	COG4122	O-methyltransferase activity
GFM36_RS07330	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GFM36_RS07345	COG1522	sequence-specific DNA binding
GFM36_RS07350	COG5006	permease, DMT superfamily
GFM36_RS07360	COG1560	Kdo2-lipid A biosynthetic process
GFM36_RS07375	COG2814	Major facilitator Superfamily
GFM36_RS07395	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFM36_RS07425	COG0583	DNA-binding transcription factor activity
GFM36_RS07430	COG1914	H( )-stimulated, divalent metal cation uptake system
GFM36_RS07450	COG4770	biotin carboxylase activity
GFM36_RS07455	COG0038	chloride channel
GFM36_RS07470	COG1309	transcriptional regulator
GFM36_RS07480	COG1063	alcohol dehydrogenase
GFM36_RS07495	COG0439	Biotin carboxylase
GFM36_RS07500	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFM36_RS07505	COG1733	regulation of RNA biosynthetic process
GFM36_RS07520	COG0864	Transcriptional regulator
GFM36_RS07530	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFM36_RS07535	COG1116	anion transmembrane transporter activity
GFM36_RS07705	COG0590	tRNA wobble adenosine to inosine editing
GFM36_RS07710	COG2807	transmembrane transport
GFM36_RS07725	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GFM36_RS07735	COG0789	Transcriptional regulator
GFM36_RS07745	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFM36_RS07765	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GFM36_RS07790	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS07795	COG0531	amino acid
GFM36_RS07800	COG1760	l-serine dehydratase
GFM36_RS07805	COG2030	dehydratase
GFM36_RS07805	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS07810	COG3396	Phenylacetate-CoA oxygenase
GFM36_RS07815	COG3460	Phenylacetate-CoA oxygenase
GFM36_RS07820	COG3396	Phenylacetate-CoA oxygenase
GFM36_RS07825	COG2151	metal-sulfur cluster biosynthetic enzyme
GFM36_RS07830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFM36_RS07835	COG1024	Enoyl-CoA hydratase
GFM36_RS07840	COG1024	Enoyl-CoA hydratase
GFM36_RS07845	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFM36_RS07850	COG0183	Belongs to the thiolase family
GFM36_RS07855	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GFM36_RS07860	COG3327	negative regulation of DNA-templated transcription, initiation
GFM36_RS07870	COG2050	protein possibly involved in aromatic compounds catabolism
GFM36_RS07880	COG0406	alpha-ribazole phosphatase activity
GFM36_RS07920	COG1278	Cold shock
GFM36_RS07955	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GFM36_RS07960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GFM36_RS07965	COG2271	Major facilitator Superfamily
GFM36_RS07970	COG0753	catalase activity
GFM36_RS07975	COG3038	cytochrome b561
GFM36_RS07980	COG0583	DNA-binding transcription factor activity
GFM36_RS07990	COG1414	Transcriptional regulator
GFM36_RS07995	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFM36_RS08010	COG1840	ABC-type Fe3 transport system, periplasmic component
GFM36_RS08015	COG3842	ATPase activity
GFM36_RS08030	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
GFM36_RS08035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFM36_RS08040	COG2814	Major facilitator Superfamily
GFM36_RS08045	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS08060	COG1024	Enoyl-CoA hydratase
GFM36_RS08070	COG2814	Major facilitator Superfamily
GFM36_RS08080	COG0183	Belongs to the thiolase family
GFM36_RS08085	COG1250	3-hydroxyacyl-CoA dehydrogenase
GFM36_RS08090	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS08095	COG1024	Enoyl-CoA hydratase
GFM36_RS08100	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS08105	COG2814	Major facilitator Superfamily
GFM36_RS08110	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GFM36_RS08115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GFM36_RS08125	COG2814	Major facilitator Superfamily
GFM36_RS08135	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS08150	COG0583	DNA-binding transcription factor activity
GFM36_RS08160	COG4770	biotin carboxylase activity
GFM36_RS08165	COG1024	Enoyl-CoA hydratase
GFM36_RS08170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFM36_RS08175	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS08180	COG1309	transcriptional regulator
GFM36_RS08185	COG0318	PFAM AMP-dependent synthetase and ligase
GFM36_RS08205	COG0583	DNA-binding transcription factor activity
GFM36_RS08255	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS08280	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GFM36_RS08300	COG0784	Response regulator, receiver
GFM36_RS08300	COG2205	protein histidine kinase activity
GFM36_RS08320	COG0765	amino acid transport
GFM36_RS08325	COG0765	amino acid transport
GFM36_RS08330	COG1126	abc transporter atp-binding protein
GFM36_RS08335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFM36_RS08340	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFM36_RS08350	COG1280	lysine exporter protein (LysE YggA)
GFM36_RS08355	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GFM36_RS08360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFM36_RS08365	COG1045	serine acetyltransferase
GFM36_RS08375	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS08380	COG0583	DNA-binding transcription factor activity
GFM36_RS08385	COG0625	glutathione transferase activity
GFM36_RS08390	COG0625	glutathione transferase activity
GFM36_RS08395	COG0583	DNA-binding transcription factor activity
GFM36_RS08405	COG1346	cytolysis
GFM36_RS08410	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFM36_RS08425	COG2814	Major facilitator Superfamily
GFM36_RS08435	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
GFM36_RS08440	COG3052	prosthetic group binding
GFM36_RS08460	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GFM36_RS08480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFM36_RS08490	COG1294	oxidase, subunit
GFM36_RS08495	COG1271	oxidase subunit
GFM36_RS08515	COG0477	Major facilitator Superfamily
GFM36_RS08525	COG4521	taurine ABC transporter
GFM36_RS08530	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
GFM36_RS08535	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFM36_RS08540	COG2175	clavaminate synthase activity
GFM36_RS08550	COG1953	Uracil, thiamine, allantoin
GFM36_RS08560	COG0583	DNA-binding transcription factor activity
GFM36_RS08570	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GFM36_RS08585	COG0640	Transcriptional regulator
GFM36_RS08590	COG0798	PFAM Bile acid sodium symporter
GFM36_RS08595	COG0583	DNA-binding transcription factor activity
GFM36_RS08610	COG3634	alkyl hydroperoxide reductase activity
GFM36_RS08650	COG0436	Aminotransferase
GFM36_RS08660	COG0386	Belongs to the glutathione peroxidase family
GFM36_RS08700	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GFM36_RS08725	COG0012	GTP binding
GFM36_RS08730	COG2011	ABC-type metal ion transport system permease component
GFM36_RS08735	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFM36_RS08745	COG1464	Belongs to the NlpA lipoprotein family
GFM36_RS08775	COG0765	amino acid transport
GFM36_RS08780	COG0765	amino acid transport
GFM36_RS08785	COG1126	abc transporter atp-binding protein
GFM36_RS08795	COG1522	sequence-specific DNA binding
GFM36_RS08810	COG1309	transcriptional regulator
GFM36_RS08830	COG0583	DNA-binding transcription factor activity
GFM36_RS08840	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
GFM36_RS08850	COG0697	spore germination
GFM36_RS08875	COG3121	Chaperone
GFM36_RS08880	COG3539	Fimbrial protein
GFM36_RS08905	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GFM36_RS08905	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GFM36_RS08950	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
GFM36_RS08960	COG2353	YceI-like domain
GFM36_RS08970	COG3698	Phosphodiester glycosidase
GFM36_RS08985	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
GFM36_RS08990	COG0506	proline dehydrogenase activity
GFM36_RS08990	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GFM36_RS08990	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
GFM36_RS09000	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFM36_RS09010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFM36_RS09030	COG1132	(ABC) transporter
GFM36_RS09035	COG3122	Protein conserved in bacteria
GFM36_RS09040	COG3619	membrane
GFM36_RS09050	COG0640	Transcriptional regulator
GFM36_RS09060	COG2850	peptidyl-arginine hydroxylation
GFM36_RS09065	COG0424	maF-like protein
GFM36_RS09085	COG0191	fructose-bisphosphate aldolase activity
GFM36_RS09090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFM36_RS09105	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
GFM36_RS09115	COG1192	Involved in chromosome partitioning
GFM36_RS09120	COG1475	DNA binding
GFM36_RS09125	COG0811	peptide transport
GFM36_RS09135	COG1132	(ABC) transporter
GFM36_RS09140	COG1663	tetraacyldisaccharide 4'-kinase activity
GFM36_RS09160	COG0084	hydrolase, TatD family'
GFM36_RS09225	COG0776	regulation of translation
GFM36_RS09255	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
GFM36_RS09260	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
GFM36_RS09300	COG4166	transmembrane transport
GFM36_RS09310	COG0339	signal peptide processing
GFM36_RS09320	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFM36_RS09355	COG0702	epimerase
GFM36_RS09360	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GFM36_RS09380	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GFM36_RS09410	COG0316	Belongs to the HesB IscA family
GFM36_RS09415	COG0822	iron-sulfur transferase activity
GFM36_RS09440	COG0776	regulation of translation
GFM36_RS09445	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GFM36_RS09450	COG2207	Transcriptional regulator
GFM36_RS09455	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFM36_RS09460	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS09465	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS09480	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GFM36_RS09495	COG2814	Major facilitator Superfamily
GFM36_RS09500	COG4264	IucA IucC family
GFM36_RS09505	COG4264	IucA IucC family
GFM36_RS09515	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
GFM36_RS09560	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GFM36_RS09565	COG0406	alpha-ribazole phosphatase activity
GFM36_RS09580	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFM36_RS09585	COG0730	response to heat
GFM36_RS09605	COG4773	Receptor
GFM36_RS09610	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFM36_RS09625	COG1131	(ABC) transporter
GFM36_RS09630	COG0842	Transport permease protein
GFM36_RS09635	COG0842	Transport permease protein
GFM36_RS09690	COG2226	methyltransferase
GFM36_RS09715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GFM36_RS09760	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFM36_RS09770	COG0133	tryptophan synthase activity
GFM36_RS09785	COG3706	GGDEF domain
GFM36_RS09800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GFM36_RS09805	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GFM36_RS09810	COG0022	dehydrogenase e1 component
GFM36_RS09815	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFM36_RS09820	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFM36_RS09830	COG1063	alcohol dehydrogenase
GFM36_RS09835	COG3781	membrane
GFM36_RS09845	COG3453	Protein conserved in bacteria
GFM36_RS09845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFM36_RS09860	COG0730	response to heat
GFM36_RS09875	COG2207	Transcriptional regulator
GFM36_RS09875	COG3708	Transcriptional regulator
GFM36_RS09880	COG1733	regulation of RNA biosynthetic process
GFM36_RS09885	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
GFM36_RS09895	COG2188	Transcriptional regulator
GFM36_RS09910	COG4521	taurine ABC transporter
GFM36_RS09915	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFM36_RS09935	COG0477	Major facilitator Superfamily
GFM36_RS09945	COG1027	Aspartate ammonia-lyase
GFM36_RS09960	COG0583	DNA-binding transcription factor activity
GFM36_RS09965	COG0583	DNA-binding transcription factor activity
GFM36_RS09970	COG0183	Belongs to the thiolase family
GFM36_RS09975	COG2031	fatty acid transporter
GFM36_RS09990	COG0583	DNA-binding transcription factor activity
GFM36_RS10000	COG2610	gluconate transmembrane transporter activity
GFM36_RS10005	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS10010	COG2207	Transcriptional regulator
GFM36_RS10025	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS10035	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFM36_RS10050	COG0543	2 iron, 2 sulfur cluster binding
GFM36_RS10050	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFM36_RS10055	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
GFM36_RS10060	COG4638	Rieske (2fe-2S)
GFM36_RS10070	COG0725	ABC transporter, periplasmic molybdate-binding protein
GFM36_RS10075	COG4149	molybdate abc transporter
GFM36_RS10080	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
GFM36_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS10090	COG1535	isochorismatase
GFM36_RS10090	COG3433	isochorismatase activity
GFM36_RS10155	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFM36_RS10170	COG0753	catalase activity
GFM36_RS10180	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
GFM36_RS10205	COG3539	Fimbrial protein
GFM36_RS10295	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GFM36_RS10410	COG1120	ATPase activity
GFM36_RS10415	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFM36_RS10425	COG1064	alcohol dehydrogenase
GFM36_RS10430	COG2207	Transcriptional regulator
GFM36_RS10435	COG2084	Dehydrogenase
GFM36_RS10445	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GFM36_RS10450	COG0583	DNA-binding transcription factor activity
GFM36_RS10460	COG0129	dihydroxy-acid dehydratase activity
GFM36_RS10465	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS10480	COG1566	PFAM secretion protein HlyD family protein
GFM36_RS10495	COG2826	transposase and inactivated derivatives, IS30 family
GFM36_RS10520	COG0583	DNA-binding transcription factor activity
GFM36_RS10535	COG2188	Transcriptional regulator
GFM36_RS10580	COG0318	PFAM AMP-dependent synthetase and ligase
GFM36_RS10590	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS10600	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS10605	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS10610	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS10615	COG0583	DNA-binding transcription factor activity
GFM36_RS10620	COG1309	transcriptional regulator
GFM36_RS10660	COG1902	pentaerythritol trinitrate reductase activity
GFM36_RS10660	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFM36_RS10675	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS10695	COG2186	Transcriptional regulator
GFM36_RS10705	COG0583	DNA-binding transcription factor activity
GFM36_RS10710	COG4948	Mandelate Racemase Muconate Lactonizing
GFM36_RS10715	COG4829	muconolactone delta-isomerase
GFM36_RS10725	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GFM36_RS10730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GFM36_RS10735	COG0183	Belongs to the thiolase family
GFM36_RS10740	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GFM36_RS10750	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS10760	COG3733	amine oxidase
GFM36_RS10770	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFM36_RS10780	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS10790	COG4638	Rieske (2fe-2S)
GFM36_RS10810	COG0154	amidase activity
GFM36_RS10820	COG2814	Major facilitator Superfamily
GFM36_RS10845	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS10850	COG0583	DNA-binding transcription factor activity
GFM36_RS10855	COG1414	Transcriptional regulator
GFM36_RS10870	COG2391	methyltransferase activity
GFM36_RS10880	COG4993	Dehydrogenase
GFM36_RS10890	COG3420	alginic acid biosynthetic process
GFM36_RS10895	COG0710	3-dehydroquinate dehydratase activity
GFM36_RS10900	COG3485	protocatechuate 3,4-dioxygenase
GFM36_RS10905	COG3485	protocatechuate 3,4-dioxygenase
GFM36_RS10910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GFM36_RS10915	COG2271	Major facilitator Superfamily
GFM36_RS10920	COG0596	Alpha beta hydrolase
GFM36_RS10925	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GFM36_RS10930	COG0183	Belongs to the thiolase family
GFM36_RS10935	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GFM36_RS10940	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
GFM36_RS10950	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
GFM36_RS10960	COG2323	membrane
GFM36_RS11005	COG1902	pentaerythritol trinitrate reductase activity
GFM36_RS11005	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFM36_RS11030	COG0542	response to heat
GFM36_RS11035	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GFM36_RS11065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFM36_RS11070	COG0569	domain protein
GFM36_RS11075	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GFM36_RS11090	COG4774	siderophore transport
GFM36_RS11095	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFM36_RS11105	COG1585	Membrane protein implicated in regulation of membrane protease activity
GFM36_RS11125	COG1294	oxidase, subunit
GFM36_RS11130	COG4890	Cyd operon protein YbgT
GFM36_RS11145	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
GFM36_RS11155	COG0552	protein localization to endoplasmic reticulum
GFM36_RS11180	COG0517	IMP dehydrogenase activity
GFM36_RS11180	COG0516	GMP reductase activity
GFM36_RS11185	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GFM36_RS11190	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
GFM36_RS11200	COG0583	DNA-binding transcription factor activity
GFM36_RS11205	COG0024	Methionine aminopeptidase
GFM36_RS11235	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFM36_RS11235	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFM36_RS11270	COG2433	Pfam Transposase IS66
GFM36_RS11280	COG3173	Aminoglycoside phosphotransferase
GFM36_RS11285	COG0488	(ABC) transporter
GFM36_RS11340	COG1132	(ABC) transporter
GFM36_RS11415	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GFM36_RS11435	COG1522	sequence-specific DNA binding
GFM36_RS11460	COG1011	Hydrolase
GFM36_RS11465	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GFM36_RS11475	COG2137	regulation of response to DNA damage stimulus
GFM36_RS11490	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFM36_RS11510	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GFM36_RS11525	COG0575	Belongs to the CDS family
GFM36_RS11530	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GFM36_RS11555	COG3852	Histidine kinase
GFM36_RS11560	COG2204	response regulator
GFM36_RS11625	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GFM36_RS11630	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
GFM36_RS11650	COG0697	spore germination
GFM36_RS11655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFM36_RS11665	COG0303	'Molybdopterin
GFM36_RS11670	COG0315	cyclic pyranopterin monophosphate synthase activity
GFM36_RS11670	COG0521	Mo-molybdopterin cofactor biosynthetic process
GFM36_RS11685	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GFM36_RS11690	COG0243	molybdopterin cofactor binding
GFM36_RS11700	COG0243	molybdopterin cofactor binding
GFM36_RS11705	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFM36_RS11710	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFM36_RS11710	COG2146	nitrite reductase [NAD(P)H] activity
GFM36_RS11720	COG0745	RESPONSE REGULATOR receiver
GFM36_RS11725	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GFM36_RS11725	COG1116	anion transmembrane transporter activity
GFM36_RS11745	COG0511	ligase activity, forming carbon-carbon bonds
GFM36_RS11760	COG2814	Major facilitator Superfamily
GFM36_RS11880	COG0592	DNA-directed DNA polymerase activity
GFM36_RS11920	COG2026	Addiction module toxin, RelE StbE family
GFM36_RS12080	COG3755	Protein conserved in bacteria
GFM36_RS12240	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GFM36_RS12290	COG0069	glutamate synthase activity
GFM36_RS12320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFM36_RS12330	COG1454	alcohol dehydrogenase
GFM36_RS12335	COG0824	Thioesterase
GFM36_RS12345	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFM36_RS12370	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
GFM36_RS12375	COG2030	dehydratase
GFM36_RS12385	COG0183	Belongs to the thiolase family
GFM36_RS12395	COG0583	DNA-binding transcription factor activity
GFM36_RS12400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GFM36_RS12410	COG1522	sequence-specific DNA binding
GFM36_RS12415	COG3135	benzoate transporter
GFM36_RS12425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFM36_RS12450	COG0589	response to stress
GFM36_RS12455	COG0488	(ABC) transporter
GFM36_RS12475	COG4773	Receptor
GFM36_RS12550	COG3409	Peptidoglycan-binding domain 1 protein
GFM36_RS12550	COG3267	Type II secretory pathway component ExeA
GFM36_RS12580	COG0681	Belongs to the peptidase S26 family
GFM36_RS12615	COG4373	Mu-like prophage FluMu protein gp28
GFM36_RS12630	COG4383	Mu-like prophage protein gp29
GFM36_RS12635	COG2369	cell adhesion
GFM36_RS12640	COG5005	Phage virion morphogenesis
GFM36_RS12655	COG4397	Mu-like prophage major head subunit gpT
GFM36_RS12770	COG0668	transmembrane transport
GFM36_RS12780	COG1309	transcriptional regulator
GFM36_RS12800	COG1605	Chorismate mutase
GFM36_RS12850	COG0308	aminopeptidase N
GFM36_RS12875	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GFM36_RS12880	COG1454	alcohol dehydrogenase
GFM36_RS12900	COG0531	amino acid
GFM36_RS12905	COG4303	Ethanolamine ammonia lyase large subunit
GFM36_RS12910	COG4302	ethanolamine ammonia-lyase activity
GFM36_RS12915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GFM36_RS12915	COG0519	Catalyzes the synthesis of GMP from XMP
GFM36_RS12920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GFM36_RS12930	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GFM36_RS12945	COG0697	spore germination
GFM36_RS12950	COG1923	regulation of RNA biosynthetic process
GFM36_RS12960	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GFM36_RS12965	COG0802	atpase or kinase
GFM36_RS12985	COG1187	pseudouridine synthase activity
GFM36_RS13000	COG0583	DNA-binding transcription factor activity
GFM36_RS13015	COG2814	Major facilitator Superfamily
GFM36_RS13020	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFM36_RS13050	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFM36_RS13430	COG0729	surface antigen
GFM36_RS13450	COG0174	glutamine synthetase
GFM36_RS13455	COG0745	RESPONSE REGULATOR receiver
GFM36_RS13460	COG2205	protein histidine kinase activity
GFM36_RS13465	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GFM36_RS13470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GFM36_RS13475	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GFM36_RS13500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFM36_RS13505	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFM36_RS13510	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS13540	COG0583	DNA-binding transcription factor activity
GFM36_RS13555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GFM36_RS13565	COG3658	cytochrome
GFM36_RS13570	COG1215	transferase activity, transferring glycosyl groups
GFM36_RS13575	COG0726	polysaccharide deacetylase
GFM36_RS13575	COG1649	PFAM Uncharacterised BCR, COG1649
GFM36_RS13600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GFM36_RS13605	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GFM36_RS13615	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GFM36_RS13640	COG0305	Participates in initiation and elongation during chromosome replication
GFM36_RS13645	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GFM36_RS13655	COG1305	Transglutaminase-like
GFM36_RS13665	COG2308	Evidence 4 Homologs of previously reported genes of
GFM36_RS13695	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
GFM36_RS13700	COG0138	bifunctional purine biosynthesis protein purh
GFM36_RS13705	COG0151	Belongs to the GarS family
GFM36_RS13710	COG1464	Belongs to the NlpA lipoprotein family
GFM36_RS13715	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFM36_RS13720	COG2011	ABC-type metal ion transport system permease component
GFM36_RS13725	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GFM36_RS13735	COG1301	dicarboxylic acid transport
GFM36_RS13765	COG1794	racemase activity, acting on amino acids and derivatives
GFM36_RS13785	COG0745	RESPONSE REGULATOR receiver
GFM36_RS13790	COG0642	Histidine kinase
GFM36_RS13795	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFM36_RS13805	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFM36_RS13845	COG2351	hydroxyisourate hydrolase activity
GFM36_RS13855	COG3008	intermembrane lipid transfer
GFM36_RS13855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
GFM36_RS13860	COG2995	paraquat-inducible protein a
GFM36_RS13875	COG2826	transposase and inactivated derivatives, IS30 family
GFM36_RS13890	COG0477	Major facilitator Superfamily
GFM36_RS13910	COG2826	transposase and inactivated derivatives, IS30 family
GFM36_RS13965	COG2186	Transcriptional regulator
GFM36_RS13975	COG0786	glutamate:sodium symporter activity
GFM36_RS13980	COG3243	poly(R)-hydroxyalkanoic acid synthase
GFM36_RS14005	COG3111	PFAM Bacterial OB fold (BOF) protein
GFM36_RS14105	COG1610	YqeY-like protein
GFM36_RS14110	COG4783	chaperone-mediated protein folding
GFM36_RS14135	COG1286	toxin biosynthetic process
GFM36_RS14165	COG0778	Nitroreductase
GFM36_RS14175	COG0513	Belongs to the DEAD box helicase family
GFM36_RS14200	COG2363	Small membrane protein
GFM36_RS14230	COG4650	regulator
GFM36_RS14235	COG1234	tRNA 3'-trailer cleavage
GFM36_RS14240	COG1690	Belongs to the RtcB family
GFM36_RS14260	COG2195	Cleaves the N-terminal amino acid of tripeptides
GFM36_RS14270	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GFM36_RS14285	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS14290	COG1301	dicarboxylic acid transport
GFM36_RS14295	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GFM36_RS14300	COG3139	Protein of unknown function (DUF1315)
GFM36_RS14305	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GFM36_RS14310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFM36_RS14320	COG0494	nUDIX hydrolase
GFM36_RS14330	COG0642	Histidine kinase
GFM36_RS14350	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
GFM36_RS14360	COG1720	tRNA m6t6A37 methyltransferase activity
GFM36_RS14370	COG0384	phenazine biosynthesis protein PhzF
GFM36_RS14375	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFM36_RS14380	COG0826	peptidase U32
GFM36_RS14385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GFM36_RS14395	COG4598	ABC transporter
GFM36_RS14400	COG4160	amino acid transport
GFM36_RS14405	COG4215	(ABC) transporter
GFM36_RS14420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFM36_RS14465	COG1131	(ABC) transporter
GFM36_RS14470	COG0842	Transport permease protein
GFM36_RS14485	COG0772	Belongs to the SEDS family
GFM36_RS14490	COG2951	lytic endotransglycosylase activity
GFM36_RS14515	COG2207	Transcriptional regulator
GFM36_RS14530	COG0052	Belongs to the universal ribosomal protein uS2 family
GFM36_RS14535	COG0024	Methionine aminopeptidase
GFM36_RS14545	COG2223	nitrite transmembrane transporter activity
GFM36_RS14555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFM36_RS14560	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GFM36_RS14565	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS14580	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GFM36_RS14585	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GFM36_RS14590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GFM36_RS14610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFM36_RS14615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GFM36_RS14620	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GFM36_RS14655	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GFM36_RS14665	COG0174	glutamine synthetase
GFM36_RS14680	COG0512	Glutamine amidotransferase of anthranilate synthase
GFM36_RS14685	COG0308	aminopeptidase N
GFM36_RS14715	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GFM36_RS14725	COG0302	gtp cyclohydrolase
GFM36_RS14745	COG3739	integral membrane protein
GFM36_RS14760	COG1169	isochorismate synthase
GFM36_RS14770	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
GFM36_RS14775	COG1132	(ABC) transporter
GFM36_RS14780	COG1132	(ABC) transporter
GFM36_RS14795	COG3433	isochorismatase activity
GFM36_RS14795	COG1535	isochorismatase
GFM36_RS14800	COG1021	2,3-dihydroxybenzoate-AMP ligase
GFM36_RS14805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GFM36_RS14815	COG4774	siderophore transport
GFM36_RS14820	COG4607	ABC-type enterochelin transport system periplasmic component
GFM36_RS14825	COG4604	ABC transporter, ATP-binding protein
GFM36_RS14830	COG4605	iron ion homeostasis
GFM36_RS14835	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GFM36_RS14840	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GFM36_RS14855	COG2964	Protein conserved in bacteria
GFM36_RS14865	COG1741	Belongs to the pirin family
GFM36_RS14900	COG2879	small protein
GFM36_RS14905	COG1966	Carbon starvation protein
GFM36_RS14925	COG4943	cyclic-guanylate-specific phosphodiesterase activity
GFM36_RS14950	COG1067	ATP-dependent peptidase activity
GFM36_RS14955	COG0583	DNA-binding transcription factor activity
GFM36_RS14980	COG1686	Belongs to the peptidase S11 family
GFM36_RS14985	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GFM36_RS15020	COG0616	signal peptide processing
GFM36_RS15025	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GFM36_RS15035	COG0573	inorganic phosphate transmembrane transporter activity
GFM36_RS15040	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GFM36_RS15045	COG1113	amino acid transport
GFM36_RS15050	COG3961	Belongs to the TPP enzyme family
GFM36_RS15055	COG1522	sequence-specific DNA binding
GFM36_RS15065	COG0076	glutamate decarboxylase activity
GFM36_RS15070	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GFM36_RS15080	COG1309	transcriptional regulator
GFM36_RS15095	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFM36_RS15130	COG0352	thiamine-phosphate diphosphorylase activity
GFM36_RS15155	COG0612	Peptidase, M16
GFM36_RS15165	COG1823	symporter activity
GFM36_RS15170	COG0583	DNA-binding transcription factor activity
GFM36_RS15175	COG0477	Major facilitator Superfamily
GFM36_RS15200	COG1187	pseudouridine synthase activity
GFM36_RS15215	COG1686	Belongs to the peptidase S11 family
GFM36_RS15220	COG1252	NADH dehydrogenase
GFM36_RS15230	COG0415	Belongs to the DNA photolyase family
GFM36_RS15245	COG1215	transferase activity, transferring glycosyl groups
GFM36_RS15280	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GFM36_RS15350	COG2070	2-Nitropropane dioxygenase
GFM36_RS15405	COG0556	nucleotide-excision repair
GFM36_RS15425	COG0436	Aminotransferase
GFM36_RS15435	COG0443	Heat shock 70 kDa protein
GFM36_RS15465	COG4221	oxidoreductase activity
GFM36_RS15475	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GFM36_RS15480	COG1381	Involved in DNA repair and RecF pathway recombination
GFM36_RS15490	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GFM36_RS15505	COG0681	Belongs to the peptidase S26 family
GFM36_RS15520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GFM36_RS15540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GFM36_RS15545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GFM36_RS15550	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GFM36_RS15560	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GFM36_RS15565	COG4208	sulfate ABC transporter
GFM36_RS15570	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
GFM36_RS15575	COG0583	DNA-binding transcription factor activity
GFM36_RS15580	COG4625	pathogenesis
GFM36_RS15595	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
GFM36_RS15610	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GFM36_RS15620	COG1051	belongs to the nudix hydrolase family
GFM36_RS15620	COG1056	cytidyltransferase-related domain
GFM36_RS15625	COG1024	Enoyl-CoA hydratase
GFM36_RS15640	COG2814	Major facilitator Superfamily
GFM36_RS15645	COG0047	phosphoribosylformylglycinamidine synthase activity
GFM36_RS15645	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GFM36_RS15665	COG1473	amidohydrolase
GFM36_RS15670	COG0824	Thioesterase
GFM36_RS15690	COG0823	Involved in the tonB-independent uptake of proteins
GFM36_RS15710	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFM36_RS15745	COG0628	permease
GFM36_RS15755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GFM36_RS15760	COG0596	Alpha beta hydrolase
GFM36_RS15765	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GFM36_RS15765	COG0616	signal peptide processing
GFM36_RS15775	COG0658	competence protein
GFM36_RS15775	COG2333	competence protein COMEC
GFM36_RS15780	COG1136	(ABC) transporter
GFM36_RS15785	COG4591	ABC-type transport system involved in lipoprotein release permease component
GFM36_RS15820	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFM36_RS15840	COG0463	Glycosyl transferase, family 2
GFM36_RS15870	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GFM36_RS15875	COG1280	lysine exporter protein (LysE YggA)
GFM36_RS15880	COG2267	carboxylic ester hydrolase activity
GFM36_RS15890	COG0019	diaminopimelate decarboxylase activity
GFM36_RS15900	COG1113	amino acid transport
GFM36_RS15905	COG1115	amino acid carrier protein
GFM36_RS15920	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
GFM36_RS15930	COG3339	Conserved Protein
GFM36_RS15935	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GFM36_RS15940	COG0243	molybdopterin cofactor binding
GFM36_RS15960	COG0778	Nitroreductase
GFM36_RS15985	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GFM36_RS16000	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GFM36_RS16020	COG0741	lytic transglycosylase activity
GFM36_RS16040	COG0584	glycerophosphoryl diester phosphodiesterase
GFM36_RS16065	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
GFM36_RS16070	COG1597	lipid kinase activity
GFM36_RS16085	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GFM36_RS16090	COG0477	Major facilitator Superfamily
GFM36_RS16140	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GFM36_RS16145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFM36_RS16170	COG0505	Belongs to the CarA family
GFM36_RS16190	COG0251	oxidation-reduction process
GFM36_RS16200	COG0589	response to stress
GFM36_RS16215	COG2843	Capsule synthesis protein
GFM36_RS16235	COG2321	neutral zinc metallopeptidase
GFM36_RS16240	COG2354	Protein conserved in bacteria
GFM36_RS16260	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFM36_RS16285	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GFM36_RS16290	COG1053	succinate dehydrogenase
GFM36_RS16295	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
GFM36_RS16300	COG2009	succinate dehydrogenase
GFM36_RS16335	COG2921	Belongs to the UPF0250 family
GFM36_RS16340	COG0321	lipoyl(octanoyl) transferase activity
GFM36_RS16355	COG0531	amino acid
GFM36_RS16370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GFM36_RS16375	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GFM36_RS16375	COG1648	precorrin-2 dehydrogenase activity
GFM36_RS16390	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
GFM36_RS16415	COG0671	phosphoesterase, PA-phosphatase related
GFM36_RS16420	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFM36_RS16430	COG1538	Outer membrane efflux protein
GFM36_RS16435	COG0393	Putative heavy-metal-binding
GFM36_RS16440	COG0393	Putative heavy-metal-binding
GFM36_RS16450	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS16460	COG0525	valine-tRNA ligase activity
GFM36_RS16465	COG2226	methyltransferase
GFM36_RS16480	COG0583	DNA-binding transcription factor activity
GFM36_RS16485	COG0004	ammonium transporteR
GFM36_RS16510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GFM36_RS16520	COG5002	protein histidine kinase activity
GFM36_RS16525	COG0745	RESPONSE REGULATOR receiver
GFM36_RS16570	COG0745	RESPONSE REGULATOR receiver
GFM36_RS16575	COG2194	sulfuric ester hydrolase activity
GFM36_RS16595	COG1752	Esterase of the alpha-beta hydrolase superfamily
GFM36_RS16610	COG2315	Protein conserved in bacteria
GFM36_RS16615	COG0142	geranyltranstransferase activity
GFM36_RS16620	COG2828	Protein conserved in bacteria
GFM36_RS16625	COG1113	amino acid transport
GFM36_RS16635	COG0582	viral genome integration into host DNA
GFM36_RS16675	COG0305	Participates in initiation and elongation during chromosome replication
GFM36_RS16770	COG2207	Transcriptional regulator
GFM36_RS16795	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFM36_RS16805	COG0560	Phosphoserine phosphatase
GFM36_RS16815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
GFM36_RS16825	COG1530	ribonuclease E activity
GFM36_RS16830	COG0424	maF-like protein
GFM36_RS16835	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
GFM36_RS16840	COG1792	Involved in formation and maintenance of cell shape
GFM36_RS16845	COG1077	Cell shape determining protein MreB Mrl
GFM36_RS16850	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFM36_RS16860	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GFM36_RS16885	COG3590	peptidase
GFM36_RS16890	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
GFM36_RS16895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFM36_RS16900	COG1752	Esterase of the alpha-beta hydrolase superfamily
GFM36_RS16905	COG1115	amino acid carrier protein
GFM36_RS16925	COG2814	Major facilitator Superfamily
GFM36_RS16930	COG1289	transmembrane transporter activity
GFM36_RS16940	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GFM36_RS16980	COG1376	ErfK ybiS ycfS ynhG family protein
GFM36_RS16985	COG2832	Protein of unknown function (DUF454)
GFM36_RS16995	COG5510	response to toxic substance
GFM36_RS17015	COG0840	transmembrane signaling receptor activity
GFM36_RS17055	COG3422	double-strand break repair
GFM36_RS17060	COG2824	Alkylphosphonate utilization operon protein PhnA
GFM36_RS17065	COG3189	MarR family transcriptional regulator
GFM36_RS17075	COG0354	folic acid binding
GFM36_RS17080	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GFM36_RS17090	COG0679	Auxin Efflux Carrier
GFM36_RS17095	COG1902	pentaerythritol trinitrate reductase activity
GFM36_RS17100	COG4772	TonB-dependent receptor
GFM36_RS17105	COG2094	Belongs to the DNA glycosylase MPG family
GFM36_RS17130	COG1217	gtp-binding protein TYPA
GFM36_RS17135	COG2233	PERMEase
GFM36_RS17145	COG0833	amino acid
GFM36_RS17150	COG1690	Belongs to the RtcB family
GFM36_RS17160	COG2885	chlorophyll binding
GFM36_RS17160	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
GFM36_RS17170	COG0183	Belongs to the thiolase family
GFM36_RS17190	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GFM36_RS17210	COG2207	Transcriptional regulator
GFM36_RS17215	COG0183	Belongs to the thiolase family
GFM36_RS17245	COG1272	protein, Hemolysin III
GFM36_RS17250	COG0477	Major facilitator Superfamily
GFM36_RS17265	COG0450	alkyl hydroperoxide reductase
GFM36_RS17285	COG0285	dihydrofolate synthase activity
GFM36_RS17330	COG4206	TonB-dependent receptor
GFM36_RS17335	COG2096	Adenosyltransferase
GFM36_RS17340	COG0584	glycerophosphoryl diester phosphodiesterase
GFM36_RS17355	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GFM36_RS17360	COG0745	RESPONSE REGULATOR receiver
GFM36_RS17365	COG2205	protein histidine kinase activity
GFM36_RS17375	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS17380	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS17430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GFM36_RS17450	COG0438	transferase activity, transferring glycosyl groups
GFM36_RS17455	COG0463	Glycosyl transferase, family 2
GFM36_RS17460	COG0726	polysaccharide deacetylase
GFM36_RS17480	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GFM36_RS17485	COG2205	protein histidine kinase activity
GFM36_RS17520	COG1862	Preprotein translocase
GFM36_RS17530	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GFM36_RS17535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GFM36_RS17545	COG3781	membrane
GFM36_RS17550	COG0613	PHP domain protein
GFM36_RS17560	COG2350	Protein conserved in bacteria
GFM36_RS17590	COG1607	acyl-coa hydrolase
GFM36_RS17650	COG2199	diguanylate cyclase activity
GFM36_RS17660	COG1408	metallophosphoesterase
GFM36_RS17665	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GFM36_RS17675	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFM36_RS17695	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
GFM36_RS17700	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GFM36_RS17715	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GFM36_RS17725	COG2969	positive regulation of protein catabolic process
GFM36_RS17745	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS17750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFM36_RS17765	COG1309	transcriptional regulator
GFM36_RS17770	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS17815	COG1183	phosphatidylcholine synthase activity
GFM36_RS17820	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
GFM36_RS17850	COG0741	lytic transglycosylase activity
GFM36_RS17850	COG1196	nuclear chromosome segregation
GFM36_RS17850	COG0739	heme binding
GFM36_RS17860	COG1702	phosphate starvation-inducible protein PhoH
GFM36_RS17895	COG1295	ribonuclease BN
GFM36_RS17900	COG0697	spore germination
GFM36_RS17905	COG2169	Transcriptional regulator
GFM36_RS17910	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFM36_RS17955	COG0557	exoribonuclease II activity
GFM36_RS17960	COG0339	signal peptide processing
GFM36_RS17965	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
GFM36_RS17995	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
GFM36_RS18000	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS18155	COG0626	cystathionine gamma-synthase activity
GFM36_RS18160	COG0433	COG0433 Predicted ATPase
GFM36_RS18165	COG1017	nitric oxide dioxygenase activity
GFM36_RS18165	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GFM36_RS18170	COG1959	2 iron, 2 sulfur cluster binding
GFM36_RS18185	COG1301	dicarboxylic acid transport
GFM36_RS18190	COG1946	Acyl-CoA thioesterase
GFM36_RS18210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GFM36_RS18215	COG1040	competence protein
GFM36_RS18220	COG0494	nUDIX hydrolase
GFM36_RS18230	COG0598	Magnesium transport protein CorA
GFM36_RS18240	COG2854	intermembrane phospholipid transfer
GFM36_RS18250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GFM36_RS18255	COG1127	ABC transporter
GFM36_RS18265	COG0513	Belongs to the DEAD box helicase family
GFM36_RS18285	COG0408	coproporphyrinogen oxidase activity
GFM36_RS18300	COG1960	acyl-CoA dehydrogenase activity
GFM36_RS18310	COG1983	PspC domain protein
GFM36_RS18315	COG0517	IMP dehydrogenase activity
GFM36_RS18370	COG0583	DNA-binding transcription factor activity
GFM36_RS18410	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS18420	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GFM36_RS18425	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GFM36_RS18430	COG0833	amino acid
GFM36_RS18460	COG1192	Involved in chromosome partitioning
GFM36_RS18465	COG0628	permease
GFM36_RS18475	COG1289	transmembrane transporter activity
GFM36_RS18490	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFM36_RS18495	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
GFM36_RS18505	COG0277	FAD linked oxidase domain protein
GFM36_RS18510	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFM36_RS18535	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GFM36_RS18540	COG5380	lipid catabolic process
GFM36_RS18560	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GFM36_RS18610	COG0194	GDP metabolic process
GFM36_RS18625	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFM36_RS18645	COG3307	-O-antigen
GFM36_RS18665	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GFM36_RS18670	COG1704	LemA family
GFM36_RS18680	COG0493	'glutamate synthase
GFM36_RS18685	COG0070	glutamate synthase
GFM36_RS18685	COG0069	glutamate synthase activity
GFM36_RS18685	COG0067	glutamate synthase
GFM36_RS18735	COG2226	methyltransferase
GFM36_RS18750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFM36_RS18755	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GFM36_RS18800	COG0833	amino acid
GFM36_RS18865	COG0488	(ABC) transporter
GFM36_RS18875	COG4221	oxidoreductase activity
GFM36_RS18880	COG0659	secondary active sulfate transmembrane transporter activity
GFM36_RS18905	COG0427	acetyl-CoA hydrolase
GFM36_RS18935	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GFM36_RS18955	COG1132	(ABC) transporter
GFM36_RS18970	COG2329	Antibiotic biosynthesis monooxygenase
GFM36_RS18985	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GFM36_RS19040	COG2207	Transcriptional regulator
GFM36_RS19045	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
GFM36_RS19060	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFM36_RS19065	COG1733	regulation of RNA biosynthetic process
GFM36_RS19075	COG1129	ABC transporter
GFM36_RS19095	COG0667	Aldo Keto reductase
GFM36_RS19145	COG0583	DNA-binding transcription factor activity
GFM36_RS19150	COG2814	Major facilitator Superfamily
GFM36_RS19255	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GFM36_RS19280	COG1335	isochorismatase
GFM36_RS19290	COG1012	belongs to the aldehyde dehydrogenase family
GFM36_RS19295	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
GFM36_RS19305	COG1113	amino acid transport
GFM36_RS19315	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GFM36_RS19330	COG2814	Major facilitator Superfamily
GFM36_RS19340	COG0351	phosphomethylpyrimidine kinase
GFM36_RS19340	COG0352	thiamine-phosphate diphosphorylase activity
GFM36_RS19340	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GFM36_RS19360	COG1309	transcriptional regulator
GFM36_RS19365	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFM36_RS19380	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GFM36_RS19390	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFM36_RS19395	COG3162	membrane
GFM36_RS19400	COG2198	Histidine kinase
GFM36_RS19400	COG2205	protein histidine kinase activity
GFM36_RS19400	COG0784	Response regulator, receiver
GFM36_RS19425	COG1522	sequence-specific DNA binding
GFM36_RS19430	COG1335	isochorismatase
GFM36_RS19435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GFM36_RS19445	COG0668	transmembrane transport
GFM36_RS19450	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GFM36_RS19455	COG1519	Transferase
GFM36_RS19460	COG1902	pentaerythritol trinitrate reductase activity
GFM36_RS19480	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GFM36_RS19505	COG0426	domain, Protein
GFM36_RS19505	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GFM36_RS19510	COG4774	siderophore transport
GFM36_RS19515	COG2119	membrane
GFM36_RS19525	COG0508	dehydrogenase complex catalyzes the overall conversion of
GFM36_RS19535	COG4942	peptidase
GFM36_RS19550	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GFM36_RS19560	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GFM36_RS19580	COG0189	ligase activity
GFM36_RS19605	COG0708	Exodeoxyribonuclease III
GFM36_RS19610	COG1393	Belongs to the ArsC family
GFM36_RS19625	COG3706	GGDEF domain
GFM36_RS19660	COG2351	hydroxyisourate hydrolase activity
GFM36_RS19665	COG2233	PERMEase
GFM36_RS19675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GFM36_RS19685	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
GFM36_RS19690	COG1028	Short-chain dehydrogenase reductase Sdr
GFM36_RS19700	COG3150	esterase
GFM36_RS19770	COG2918	glutathione biosynthetic process
GFM36_RS19785	COG2733	membrane
GFM36_RS19790	COG0436	Aminotransferase
GFM36_RS19795	COG0534	Mate efflux family protein
GFM36_RS19880	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GFM36_RS19885	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
GFM36_RS19895	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GFM36_RS19900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GFM36_RS19915	COG0010	Belongs to the arginase family
GFM36_RS19945	COG2188	Transcriptional regulator
GFM36_RS19955	COG0523	cobalamin synthesis protein
GFM36_RS19965	COG1113	amino acid transport
GFM36_RS19975	COG0625	glutathione transferase activity
GFM36_RS19995	COG1683	Conserved Protein
GFM36_RS20000	COG0534	Mate efflux family protein
GFM36_RS20005	COG0385	Bile acid
GFM36_RS20010	COG1335	isochorismatase
GFM36_RS20015	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFM36_RS20035	COG2116	formate transmembrane transporter activity
GFM36_RS20040	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GFM36_RS20045	COG2133	pyrroloquinoline quinone binding
GFM36_RS20050	COG2983	Belongs to the UPF0260 family
GFM36_RS20070	COG1194	a g-specific adenine glycosylase
GFM36_RS20085	COG2818	Glycosylase
GFM36_RS20090	COG1064	alcohol dehydrogenase
GFM36_RS20095	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFM36_RS20110	COG0583	DNA-binding transcription factor activity
GFM36_RS20115	COG0656	L-ascorbic acid biosynthetic process
GFM36_RS20120	COG2814	Major facilitator Superfamily
GFM36_RS20155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GFM36_RS20170	COG2233	PERMEase
GFM36_RS20175	COG0583	DNA-binding transcription factor activity
GFM36_RS20210	COG0733	neurotransmitter:sodium symporter activity
GFM36_RS20255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GFM36_RS20260	COG0657	acetylesterase activity
GFM36_RS20280	COG0583	DNA-binding transcription factor activity
GFM36_RS20310	COG2951	lytic endotransglycosylase activity
GFM36_RS20315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GFM36_RS20330	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GFM36_RS20340	COG0671	phosphoesterase, PA-phosphatase related
GFM36_RS20345	COG0861	Integral membrane protein TerC family
GFM36_RS20355	COG0754	glutathionylspermidine amidase activity
GFM36_RS20365	COG0402	S-adenosylhomocysteine deaminase activity
GFM36_RS20380	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
GFM36_RS20385	COG1230	cation diffusion facilitator family transporter
GFM36_RS20400	COG0706	membrane insertase activity