locus-tag	class	description
CK824_RS00010	COG0592	DNA-directed DNA polymerase activity
CK824_RS00020	COG0187	DNA topoisomerase II activity
CK824_RS00030	COG0586	Pfam SNARE associated Golgi protein
CK824_RS00035	COG0488	(ABC) transporter
CK824_RS00060	COG0596	Alpha beta hydrolase
CK824_RS00065	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
CK824_RS00070	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
CK824_RS00115	COG0733	neurotransmitter:sodium symporter activity
CK824_RS00155	COG2233	PERMEase
CK824_RS00170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_RS00205	COG2814	Major facilitator Superfamily
CK824_RS00210	COG0656	L-ascorbic acid biosynthetic process
CK824_RS00215	COG0583	DNA-binding transcription factor activity
CK824_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_RS00235	COG1064	alcohol dehydrogenase
CK824_RS00240	COG2818	Glycosylase
CK824_RS00255	COG1194	a g-specific adenine glycosylase
CK824_RS00275	COG2983	Belongs to the UPF0260 family
CK824_RS00280	COG2133	pyrroloquinoline quinone binding
CK824_RS00285	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
CK824_RS00290	COG2116	formate transmembrane transporter activity
CK824_RS00310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK824_RS00315	COG1335	isochorismatase
CK824_RS00320	COG0385	Bile acid
CK824_RS00325	COG0534	Mate efflux family protein
CK824_RS00330	COG1683	Conserved Protein
CK824_RS00350	COG0625	glutathione transferase activity
CK824_RS00360	COG1113	amino acid transport
CK824_RS00370	COG0523	cobalamin synthesis protein
CK824_RS00380	COG2188	Transcriptional regulator
CK824_RS00410	COG0010	Belongs to the arginase family
CK824_RS00430	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CK824_RS00435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CK824_RS00445	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
CK824_RS00450	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
CK824_RS00555	COG0534	Mate efflux family protein
CK824_RS00560	COG0436	Aminotransferase
CK824_RS00565	COG2733	membrane
CK824_RS00580	COG2918	glutathione biosynthetic process
CK824_RS00595	COG1388	LysM domain
CK824_RS00595	COG0791	NLP P60 protein
CK824_RS00615	COG3150	esterase
CK824_RS00625	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS00630	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
CK824_RS00640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_RS00650	COG2233	PERMEase
CK824_RS00655	COG2351	hydroxyisourate hydrolase activity
CK824_RS00690	COG3706	GGDEF domain
CK824_RS00705	COG1393	Belongs to the ArsC family
CK824_RS00710	COG0708	Exodeoxyribonuclease III
CK824_RS00730	COG0189	ligase activity
CK824_RS00750	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
CK824_RS00760	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CK824_RS00775	COG4942	peptidase
CK824_RS00785	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK824_RS00795	COG2119	membrane
CK824_RS00800	COG4774	siderophore transport
CK824_RS00805	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_RS00805	COG0426	domain, Protein
CK824_RS00830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
CK824_RS00850	COG1902	pentaerythritol trinitrate reductase activity
CK824_RS00855	COG1519	Transferase
CK824_RS00860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CK824_RS00865	COG0668	transmembrane transport
CK824_RS00875	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK824_RS00880	COG1335	isochorismatase
CK824_RS00885	COG1522	sequence-specific DNA binding
CK824_RS00890	COG3328	transposase activity
CK824_RS00915	COG0784	Response regulator, receiver
CK824_RS00915	COG2205	protein histidine kinase activity
CK824_RS00915	COG2198	Histidine kinase
CK824_RS00920	COG3162	membrane
CK824_RS00925	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK824_RS00935	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_RS00955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CK824_RS00960	COG1309	transcriptional regulator
CK824_RS00980	COG0351	phosphomethylpyrimidine kinase
CK824_RS00980	COG0352	thiamine-phosphate diphosphorylase activity
CK824_RS00980	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CK824_RS00990	COG2814	Major facilitator Superfamily
CK824_RS01005	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CK824_RS01015	COG1113	amino acid transport
CK824_RS01025	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CK824_RS01030	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS01040	COG1335	isochorismatase
CK824_RS01070	COG2814	Major facilitator Superfamily
CK824_RS01075	COG0583	DNA-binding transcription factor activity
CK824_RS01100	COG0667	Aldo Keto reductase
CK824_RS01135	COG1733	regulation of RNA biosynthetic process
CK824_RS01145	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK824_RS01210	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
CK824_RS01225	COG2329	Antibiotic biosynthesis monooxygenase
CK824_RS01255	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
CK824_RS01285	COG0427	acetyl-CoA hydrolase
CK824_RS01310	COG0659	secondary active sulfate transmembrane transporter activity
CK824_RS01315	COG4221	oxidoreductase activity
CK824_RS01320	COG2873	o-acetylhomoserine
CK824_RS01325	COG0488	(ABC) transporter
CK824_RS01410	COG0833	amino acid
CK824_RS01455	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
CK824_RS01460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CK824_RS01475	COG2226	methyltransferase
CK824_RS01525	COG0069	glutamate synthase activity
CK824_RS01525	COG0070	glutamate synthase
CK824_RS01525	COG0067	glutamate synthase
CK824_RS01530	COG0493	'glutamate synthase
CK824_RS01540	COG1704	LemA family
CK824_RS01545	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
CK824_RS01555	COG4969	Belongs to the N-Me-Phe pilin family
CK824_RS01560	COG3307	-O-antigen
CK824_RS01580	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK824_RS01595	COG0194	GDP metabolic process
CK824_RS01645	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
CK824_RS01665	COG5380	lipid catabolic process
CK824_RS01670	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
CK824_RS01685	COG1061	Type III restriction enzyme res subunit
CK824_RS01695	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK824_RS01700	COG1192	Involved in chromosome partitioning
CK824_RS01710	COG1061	Type III restriction enzyme res subunit
CK824_RS01730	COG1061	Type III restriction enzyme res subunit
CK824_RS01740	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK824_RS01745	COG1192	Involved in chromosome partitioning
CK824_RS01755	COG1061	Type III restriction enzyme res subunit
CK824_RS01790	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CK824_RS01795	COG0277	FAD linked oxidase domain protein
CK824_RS01805	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
CK824_RS01810	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK824_RS01825	COG1289	transmembrane transporter activity
CK824_RS01835	COG0628	permease
CK824_RS01840	COG1192	Involved in chromosome partitioning
CK824_RS01870	COG0833	amino acid
CK824_RS01875	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CK824_RS01880	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK824_RS01890	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS01935	COG0583	DNA-binding transcription factor activity
CK824_RS01980	COG0517	IMP dehydrogenase activity
CK824_RS01985	COG1983	PspC domain protein
CK824_RS01995	COG1960	acyl-CoA dehydrogenase activity
CK824_RS02010	COG0408	coproporphyrinogen oxidase activity
CK824_RS02030	COG0513	Belongs to the DEAD box helicase family
CK824_RS02035	COG1127	ABC transporter
CK824_RS02040	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
CK824_RS02050	COG2854	intermembrane phospholipid transfer
CK824_RS02060	COG0598	Magnesium transport protein CorA
CK824_RS02070	COG0494	nUDIX hydrolase
CK824_RS02075	COG1040	competence protein
CK824_RS02080	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CK824_RS02100	COG1946	Acyl-CoA thioesterase
CK824_RS02105	COG1301	dicarboxylic acid transport
CK824_RS02120	COG1959	2 iron, 2 sulfur cluster binding
CK824_RS02125	COG1017	nitric oxide dioxygenase activity
CK824_RS02125	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK824_RS02130	COG0433	COG0433 Predicted ATPase
CK824_RS02135	COG0626	cystathionine gamma-synthase activity
CK824_RS02290	COG1960	acyl-CoA dehydrogenase activity
CK824_RS02295	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
CK824_RS02325	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
CK824_RS02330	COG0339	signal peptide processing
CK824_RS02335	COG0557	exoribonuclease II activity
CK824_RS02380	COG0179	Fumarylacetoacetate (FAA) hydrolase
CK824_RS02385	COG2169	Transcriptional regulator
CK824_RS02390	COG0697	spore germination
CK824_RS02395	COG1295	ribonuclease BN
CK824_RS02430	COG1702	phosphate starvation-inducible protein PhoH
CK824_RS02440	COG1196	nuclear chromosome segregation
CK824_RS02440	COG0741	lytic transglycosylase activity
CK824_RS02440	COG0739	heme binding
CK824_RS02470	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
CK824_RS02475	COG1183	phosphatidylcholine synthase activity
CK824_RS02520	COG1960	acyl-CoA dehydrogenase activity
CK824_RS02525	COG1309	transcriptional regulator
CK824_RS02540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CK824_RS02545	COG1960	acyl-CoA dehydrogenase activity
CK824_RS02565	COG2969	positive regulation of protein catabolic process
CK824_RS02575	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CK824_RS02590	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
CK824_RS02595	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
CK824_RS02615	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CK824_RS02625	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK824_RS02630	COG1408	metallophosphoesterase
CK824_RS02640	COG2199	diguanylate cyclase activity
CK824_RS02700	COG1607	acyl-coa hydrolase
CK824_RS02730	COG2350	Protein conserved in bacteria
CK824_RS02740	COG0613	PHP domain protein
CK824_RS02745	COG3781	membrane
CK824_RS02755	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
CK824_RS02760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
CK824_RS02770	COG1862	Preprotein translocase
CK824_RS02820	COG2205	protein histidine kinase activity
CK824_RS02825	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
CK824_RS02845	COG0726	polysaccharide deacetylase
CK824_RS02850	COG0463	Glycosyl transferase, family 2
CK824_RS02855	COG0438	transferase activity, transferring glycosyl groups
CK824_RS02920	COG0625	glutathione transferase activity
CK824_RS02925	COG0583	DNA-binding transcription factor activity
CK824_RS02930	COG1960	acyl-CoA dehydrogenase activity
CK824_RS02935	COG1960	acyl-CoA dehydrogenase activity
CK824_RS02945	COG2205	protein histidine kinase activity
CK824_RS02950	COG0745	RESPONSE REGULATOR receiver
CK824_RS02955	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
CK824_RS02975	COG2096	Adenosyltransferase
CK824_RS03025	COG0285	dihydrofolate synthase activity
CK824_RS03045	COG0450	alkyl hydroperoxide reductase
CK824_RS03060	COG0477	Major facilitator Superfamily
CK824_RS03065	COG1272	protein, Hemolysin III
CK824_RS03095	COG0183	Belongs to the thiolase family
CK824_RS03100	COG2207	Transcriptional regulator
CK824_RS03120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_RS03140	COG0183	Belongs to the thiolase family
CK824_RS03150	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
CK824_RS03150	COG2885	chlorophyll binding
CK824_RS03160	COG1690	Belongs to the RtcB family
CK824_RS03165	COG0833	amino acid
CK824_RS03175	COG2233	PERMEase
CK824_RS03180	COG1217	gtp-binding protein TYPA
CK824_RS03205	COG2094	Belongs to the DNA glycosylase MPG family
CK824_RS03210	COG4772	TonB-dependent receptor
CK824_RS03215	COG1902	pentaerythritol trinitrate reductase activity
CK824_RS03220	COG0679	Auxin Efflux Carrier
CK824_RS03230	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK824_RS03235	COG0354	folic acid binding
CK824_RS03245	COG3189	MarR family transcriptional regulator
CK824_RS03250	COG2824	Alkylphosphonate utilization operon protein PhnA
CK824_RS03255	COG3422	double-strand break repair
CK824_RS03295	COG0840	transmembrane signaling receptor activity
CK824_RS03315	COG5510	response to toxic substance
CK824_RS03325	COG2832	Protein of unknown function (DUF454)
CK824_RS03330	COG1376	ErfK ybiS ycfS ynhG family protein
CK824_RS03370	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
CK824_RS03380	COG1289	transmembrane transporter activity
CK824_RS03385	COG2814	Major facilitator Superfamily
CK824_RS03405	COG1115	amino acid carrier protein
CK824_RS03410	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK824_RS03415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CK824_RS03420	COG1133	In Escherichia coli SbmA is involved in uptake of microcin J25
CK824_RS03450	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CK824_RS03460	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
CK824_RS03465	COG1077	Cell shape determining protein MreB Mrl
CK824_RS03470	COG1792	Involved in formation and maintenance of cell shape
CK824_RS03475	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
CK824_RS03480	COG0424	maF-like protein
CK824_RS03485	COG1530	ribonuclease E activity
CK824_RS03495	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK824_RS03505	COG0560	Phosphoserine phosphatase
CK824_RS03515	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK824_RS03540	COG2207	Transcriptional regulator
CK824_RS03560	COG1113	amino acid transport
CK824_RS03565	COG2828	Protein conserved in bacteria
CK824_RS03570	COG0142	geranyltranstransferase activity
CK824_RS03575	COG2315	Protein conserved in bacteria
CK824_RS03590	COG1752	Esterase of the alpha-beta hydrolase superfamily
CK824_RS03615	COG2194	sulfuric ester hydrolase activity
CK824_RS03620	COG0745	RESPONSE REGULATOR receiver
CK824_RS03625	COG0642	Histidine kinase
CK824_RS03635	COG0004	ammonium transporteR
CK824_RS03645	COG0583	DNA-binding transcription factor activity
CK824_RS03665	COG0525	valine-tRNA ligase activity
CK824_RS03675	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS03685	COG0393	Putative heavy-metal-binding
CK824_RS03690	COG0393	Putative heavy-metal-binding
CK824_RS03695	COG1538	Outer membrane efflux protein
CK824_RS03705	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_RS03710	COG0671	phosphoesterase, PA-phosphatase related
CK824_RS03740	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
CK824_RS03755	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
CK824_RS03755	COG1648	precorrin-2 dehydrogenase activity
CK824_RS03760	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CK824_RS03765	COG1733	regulation of RNA biosynthetic process
CK824_RS03775	COG0531	amino acid
CK824_RS03790	COG0321	lipoyl(octanoyl) transferase activity
CK824_RS03795	COG2921	Belongs to the UPF0250 family
CK824_RS03835	COG2009	succinate dehydrogenase
CK824_RS03840	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
CK824_RS03845	COG1053	succinate dehydrogenase
CK824_RS03850	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CK824_RS03875	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK824_RS03895	COG2354	Protein conserved in bacteria
CK824_RS03900	COG2321	neutral zinc metallopeptidase
CK824_RS03945	COG2843	Capsule synthesis protein
CK824_RS03960	COG0589	response to stress
CK824_RS03980	COG0505	Belongs to the CarA family
CK824_RS04005	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CK824_RS04010	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CK824_RS04060	COG0477	Major facilitator Superfamily
CK824_RS04065	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
CK824_RS04080	COG1597	lipid kinase activity
CK824_RS04085	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CK824_RS04110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK824_RS04115	COG0584	glycerophosphoryl diester phosphodiesterase
CK824_RS04135	COG0741	lytic transglycosylase activity
CK824_RS04160	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CK824_RS04175	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK824_RS04205	COG0778	Nitroreductase
CK824_RS04220	COG1929	Belongs to the glycerate kinase type-1 family
CK824_RS04225	COG0243	molybdopterin cofactor binding
CK824_RS04230	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
CK824_RS04235	COG3339	Conserved Protein
CK824_RS04245	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
CK824_RS04260	COG1113	amino acid transport
CK824_RS04270	COG0019	diaminopimelate decarboxylase activity
CK824_RS04280	COG1280	lysine exporter protein (LysE YggA)
CK824_RS04285	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CK824_RS04315	COG0463	Glycosyl transferase, family 2
CK824_RS04335	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_RS04365	COG4591	ABC-type transport system involved in lipoprotein release permease component
CK824_RS04370	COG1136	(ABC) transporter
CK824_RS04375	COG0658	competence protein
CK824_RS04375	COG2333	competence protein COMEC
CK824_RS04385	COG0616	signal peptide processing
CK824_RS04385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CK824_RS04390	COG0596	Alpha beta hydrolase
CK824_RS04395	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
CK824_RS04405	COG0628	permease
CK824_RS04440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK824_RS04460	COG0823	Involved in the tonB-independent uptake of proteins
CK824_RS04480	COG0824	Thioesterase
CK824_RS04485	COG1473	amidohydrolase
CK824_RS04505	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CK824_RS04505	COG0047	phosphoribosylformylglycinamidine synthase activity
CK824_RS04510	COG2814	Major facilitator Superfamily
CK824_RS04520	COG1024	Enoyl-CoA hydratase
CK824_RS04525	COG1051	belongs to the nudix hydrolase family
CK824_RS04525	COG1056	cytidyltransferase-related domain
CK824_RS04535	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
CK824_RS04550	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
CK824_RS04565	COG4625	pathogenesis
CK824_RS04570	COG0583	DNA-binding transcription factor activity
CK824_RS04575	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
CK824_RS04580	COG4208	sulfate ABC transporter
CK824_RS04585	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
CK824_RS04595	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
CK824_RS04600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CK824_RS04605	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
CK824_RS04625	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK824_RS04640	COG0681	Belongs to the peptidase S26 family
CK824_RS04655	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
CK824_RS04665	COG1381	Involved in DNA repair and RecF pathway recombination
CK824_RS04670	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
CK824_RS04680	COG4221	oxidoreductase activity
CK824_RS04710	COG0436	Aminotransferase
CK824_RS04730	COG0556	nucleotide-excision repair
CK824_RS04785	COG2070	2-Nitropropane dioxygenase
CK824_RS04815	COG1215	transferase activity, transferring glycosyl groups
CK824_RS04830	COG0415	Belongs to the DNA photolyase family
CK824_RS04840	COG1252	NADH dehydrogenase
CK824_RS04845	COG1686	Belongs to the peptidase S11 family
CK824_RS04860	COG1187	pseudouridine synthase activity
CK824_RS04885	COG0477	Major facilitator Superfamily
CK824_RS04890	COG0583	DNA-binding transcription factor activity
CK824_RS04895	COG1823	symporter activity
CK824_RS04905	COG0612	Peptidase, M16
CK824_RS04930	COG0352	thiamine-phosphate diphosphorylase activity
CK824_RS04965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK824_RS04980	COG1309	transcriptional regulator
CK824_RS04990	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
CK824_RS04995	COG0076	glutamate decarboxylase activity
CK824_RS05005	COG1522	sequence-specific DNA binding
CK824_RS05010	COG3961	Belongs to the TPP enzyme family
CK824_RS05015	COG1113	amino acid transport
CK824_RS05020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
CK824_RS05025	COG0573	inorganic phosphate transmembrane transporter activity
CK824_RS05035	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
CK824_RS05040	COG0616	signal peptide processing
CK824_RS05075	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
CK824_RS05080	COG1686	Belongs to the peptidase S11 family
CK824_RS05105	COG0583	DNA-binding transcription factor activity
CK824_RS05110	COG1067	ATP-dependent peptidase activity
CK824_RS05155	COG1966	Carbon starvation protein
CK824_RS05160	COG2879	small protein
CK824_RS05195	COG2508	Transcriptional regulator
CK824_RS05195	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
CK824_RS05215	COG1113	amino acid transport
CK824_RS05220	COG0583	DNA-binding transcription factor activity
CK824_RS05225	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_RS05230	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_RS05240	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS05245	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_RS05250	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
CK824_RS05250	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK824_RS05285	COG2814	Major facilitator Superfamily
CK824_RS05290	COG4948	Mandelate Racemase Muconate Lactonizing
CK824_RS05300	COG1309	transcriptional regulator
CK824_RS05320	COG1741	Belongs to the pirin family
CK824_RS05330	COG2964	Protein conserved in bacteria
CK824_RS05345	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK824_RS05350	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK824_RS05355	COG4605	iron ion homeostasis
CK824_RS05360	COG4604	ABC transporter, ATP-binding protein
CK824_RS05365	COG4607	ABC-type enterochelin transport system periplasmic component
CK824_RS05370	COG4774	siderophore transport
CK824_RS05380	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
CK824_RS05385	COG1021	2,3-dihydroxybenzoate-AMP ligase
CK824_RS05390	COG1535	isochorismatase
CK824_RS05390	COG3433	isochorismatase activity
CK824_RS05405	COG1132	(ABC) transporter
CK824_RS05410	COG1132	(ABC) transporter
CK824_RS05415	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
CK824_RS05425	COG1169	isochorismate synthase
CK824_RS05440	COG3739	integral membrane protein
CK824_RS05460	COG0302	gtp cyclohydrolase
CK824_RS05470	COG1529	Aldehyde oxidase and xanthine dehydrogenase
CK824_RS05500	COG0308	aminopeptidase N
CK824_RS05505	COG0512	Glutamine amidotransferase of anthranilate synthase
CK824_RS05520	COG0174	glutamine synthetase
CK824_RS05530	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
CK824_RS05565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
CK824_RS05570	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CK824_RS05575	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CK824_RS05595	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CK824_RS05600	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CK824_RS05605	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
CK824_RS05620	COG1960	acyl-CoA dehydrogenase activity
CK824_RS05625	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CK824_RS05630	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK824_RS05640	COG2223	nitrite transmembrane transporter activity
CK824_RS05650	COG0024	Methionine aminopeptidase
CK824_RS05655	COG0052	Belongs to the universal ribosomal protein uS2 family
CK824_RS05670	COG2207	Transcriptional regulator
CK824_RS05695	COG2951	lytic endotransglycosylase activity
CK824_RS05700	COG0772	Belongs to the SEDS family
CK824_RS05715	COG0842	Transport permease protein
CK824_RS05720	COG1131	(ABC) transporter
CK824_RS05765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_RS05790	COG4215	(ABC) transporter
CK824_RS05795	COG4160	amino acid transport
CK824_RS05800	COG4598	ABC transporter
CK824_RS05810	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK824_RS05815	COG0826	peptidase U32
CK824_RS05820	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_RS05835	COG1720	tRNA m6t6A37 methyltransferase activity
CK824_RS05845	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
CK824_RS05860	COG0642	Histidine kinase
CK824_RS05870	COG0494	nUDIX hydrolase
CK824_RS05880	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CK824_RS05885	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
CK824_RS05890	COG3139	Protein of unknown function (DUF1315)
CK824_RS05895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CK824_RS05905	COG1301	dicarboxylic acid transport
CK824_RS05910	COG1960	acyl-CoA dehydrogenase activity
CK824_RS05915	COG2819	hydrolase of the alpha beta superfamily
CK824_RS05925	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
CK824_RS05935	COG2195	Cleaves the N-terminal amino acid of tripeptides
CK824_RS05940	COG1234	tRNA 3'-trailer cleavage
CK824_RS05970	COG2363	Small membrane protein
CK824_RS05990	COG0513	Belongs to the DEAD box helicase family
CK824_RS06000	COG0778	Nitroreductase
CK824_RS06030	COG1286	toxin biosynthetic process
CK824_RS06055	COG4783	chaperone-mediated protein folding
CK824_RS06060	COG1610	YqeY-like protein
CK824_RS06160	COG3111	PFAM Bacterial OB fold (BOF) protein
CK824_RS06185	COG3243	poly(R)-hydroxyalkanoic acid synthase
CK824_RS06190	COG0786	glutamate:sodium symporter activity
CK824_RS06200	COG2186	Transcriptional regulator
CK824_RS06255	COG0477	Major facilitator Superfamily
CK824_RS06285	COG2985	domain, Protein
CK824_RS06295	COG2995	paraquat-inducible protein a
CK824_RS06300	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
CK824_RS06300	COG3008	intermembrane lipid transfer
CK824_RS06310	COG1794	racemase activity, acting on amino acids and derivatives
CK824_RS06340	COG1301	dicarboxylic acid transport
CK824_RS06350	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK824_RS06355	COG2011	ABC-type metal ion transport system permease component
CK824_RS06360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CK824_RS06365	COG1464	Belongs to the NlpA lipoprotein family
CK824_RS06370	COG0151	Belongs to the GarS family
CK824_RS06375	COG0138	bifunctional purine biosynthesis protein purh
CK824_RS06380	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
CK824_RS06410	COG2308	Evidence 4 Homologs of previously reported genes of
CK824_RS06420	COG1305	Transglutaminase-like
CK824_RS06430	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CK824_RS06435	COG0305	Participates in initiation and elongation during chromosome replication
CK824_RS06460	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
CK824_RS06470	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
CK824_RS06475	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
CK824_RS06500	COG1649	PFAM Uncharacterised BCR, COG1649
CK824_RS06500	COG0726	polysaccharide deacetylase
CK824_RS06505	COG1215	transferase activity, transferring glycosyl groups
CK824_RS06510	COG3658	cytochrome
CK824_RS06520	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK824_RS06540	COG0583	DNA-binding transcription factor activity
CK824_RS06560	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK824_RS06565	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK824_RS06580	COG1960	acyl-CoA dehydrogenase activity
CK824_RS06585	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK824_RS06590	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_RS06615	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
CK824_RS06620	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
CK824_RS06630	COG2205	protein histidine kinase activity
CK824_RS06635	COG0745	RESPONSE REGULATOR receiver
CK824_RS06640	COG0174	glutamine synthetase
CK824_RS06660	COG0729	surface antigen
CK824_RS06690	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK824_RS06695	COG2814	Major facilitator Superfamily
CK824_RS06710	COG0583	DNA-binding transcription factor activity
CK824_RS06725	COG1187	pseudouridine synthase activity
CK824_RS06745	COG0802	atpase or kinase
CK824_RS06750	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
CK824_RS06760	COG1923	regulation of RNA biosynthetic process
CK824_RS06765	COG0697	spore germination
CK824_RS06780	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK824_RS06790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK824_RS06795	COG0519	Catalyzes the synthesis of GMP from XMP
CK824_RS06795	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CK824_RS06800	COG4302	ethanolamine ammonia-lyase activity
CK824_RS06805	COG4303	Ethanolamine ammonia lyase large subunit
CK824_RS06810	COG0531	amino acid
CK824_RS06830	COG1454	alcohol dehydrogenase
CK824_RS06835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK824_RS06845	COG3449	Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell
CK824_RS06865	COG0308	aminopeptidase N
CK824_RS06875	COG4221	oxidoreductase activity
CK824_RS06885	COG1605	Chorismate mutase
CK824_RS06905	COG1309	transcriptional regulator
CK824_RS06915	COG0668	transmembrane transport
CK824_RS06950	COG4773	Receptor
CK824_RS06970	COG0488	(ABC) transporter
CK824_RS06975	COG0589	response to stress
CK824_RS06990	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CK824_RS07000	COG3135	benzoate transporter
CK824_RS07005	COG1522	sequence-specific DNA binding
CK824_RS07015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CK824_RS07020	COG0583	DNA-binding transcription factor activity
CK824_RS07030	COG0183	Belongs to the thiolase family
CK824_RS07040	COG2030	dehydratase
CK824_RS07045	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK824_RS07070	COG0824	Thioesterase
CK824_RS07075	COG1454	alcohol dehydrogenase
CK824_RS07085	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CK824_RS07105	COG0069	glutamate synthase activity
CK824_RS07285	COG5410	chromosome segregation
CK824_RS07390	COG1598	PFAM Uncharacterised protein family UPF0150
CK824_RS07475	COG2814	Major facilitator Superfamily
CK824_RS07490	COG0511	ligase activity, forming carbon-carbon bonds
CK824_RS07510	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK824_RS07510	COG1116	anion transmembrane transporter activity
CK824_RS07515	COG0745	RESPONSE REGULATOR receiver
CK824_RS07525	COG2146	nitrite reductase [NAD(P)H] activity
CK824_RS07525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_RS07530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_RS07535	COG0243	molybdopterin cofactor binding
CK824_RS07545	COG0243	molybdopterin cofactor binding
CK824_RS07550	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
CK824_RS07565	COG0315	cyclic pyranopterin monophosphate synthase activity
CK824_RS07565	COG0521	Mo-molybdopterin cofactor biosynthetic process
CK824_RS07570	COG0303	'Molybdopterin
CK824_RS07580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_RS07585	COG0697	spore germination
CK824_RS07605	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
CK824_RS07610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK824_RS07670	COG2204	response regulator
CK824_RS07675	COG3852	Histidine kinase
CK824_RS07695	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
CK824_RS07700	COG0575	Belongs to the CDS family
CK824_RS07735	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK824_RS07750	COG2137	regulation of response to DNA damage stimulus
CK824_RS07760	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
CK824_RS07765	COG1011	Hydrolase
CK824_RS07790	COG1522	sequence-specific DNA binding
CK824_RS07800	COG1113	amino acid transport
CK824_RS07815	COG0659	secondary active sulfate transmembrane transporter activity
CK824_RS07840	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
CK824_RS07855	COG0640	Transcriptional regulator
CK824_RS07860	COG0798	PFAM Bile acid sodium symporter
CK824_RS07865	COG0583	DNA-binding transcription factor activity
CK824_RS07880	COG3634	alkyl hydroperoxide reductase activity
CK824_RS07920	COG0436	Aminotransferase
CK824_RS07930	COG0386	Belongs to the glutathione peroxidase family
CK824_RS07970	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
CK824_RS07995	COG0012	GTP binding
CK824_RS08000	COG2011	ABC-type metal ion transport system permease component
CK824_RS08005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CK824_RS08015	COG1464	Belongs to the NlpA lipoprotein family
CK824_RS08045	COG0765	amino acid transport
CK824_RS08050	COG0765	amino acid transport
CK824_RS08055	COG1126	abc transporter atp-binding protein
CK824_RS08065	COG1522	sequence-specific DNA binding
CK824_RS08080	COG1309	transcriptional regulator
CK824_RS08110	COG0583	DNA-binding transcription factor activity
CK824_RS08120	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CK824_RS08130	COG0697	spore germination
CK824_RS08160	COG3121	Chaperone
CK824_RS08165	COG3539	Fimbrial protein
CK824_RS08190	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
CK824_RS08190	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
CK824_RS08235	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
CK824_RS08245	COG2353	YceI-like domain
CK824_RS08255	COG3698	Phosphodiester glycosidase
CK824_RS08270	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
CK824_RS08275	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CK824_RS08275	COG0506	proline dehydrogenase activity
CK824_RS08275	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
CK824_RS08285	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CK824_RS08290	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CK824_RS08330	COG0482	sulfurtransferase activity
CK824_RS08345	COG0488	(ABC) transporter
CK824_RS08350	COG3173	Aminoglycoside phosphotransferase
CK824_RS08360	COG2433	Pfam Transposase IS66
CK824_RS08405	COG5001	Diguanylate cyclase
CK824_RS08405	COG3300	MHYT domain
CK824_RS08425	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
CK824_RS08425	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK824_RS08425	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
CK824_RS08430	COG1105	Belongs to the carbohydrate kinase PfkB family
CK824_RS08435	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK824_RS08435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CK824_RS08465	COG0024	Methionine aminopeptidase
CK824_RS08470	COG0583	DNA-binding transcription factor activity
CK824_RS08480	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
CK824_RS08485	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
CK824_RS08490	COG0516	GMP reductase activity
CK824_RS08490	COG0517	IMP dehydrogenase activity
CK824_RS08515	COG0552	protein localization to endoplasmic reticulum
CK824_RS08525	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
CK824_RS08540	COG4890	Cyd operon protein YbgT
CK824_RS08545	COG1294	oxidase, subunit
CK824_RS08560	COG1585	Membrane protein implicated in regulation of membrane protease activity
CK824_RS08570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CK824_RS08575	COG4774	siderophore transport
CK824_RS08590	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CK824_RS08595	COG0569	domain protein
CK824_RS08600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CK824_RS08630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
CK824_RS08635	COG0542	response to heat
CK824_RS08660	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_RS08660	COG1902	pentaerythritol trinitrate reductase activity
CK824_RS08705	COG2323	membrane
CK824_RS08710	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
CK824_RS08720	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CK824_RS08725	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK824_RS08730	COG0183	Belongs to the thiolase family
CK824_RS08735	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CK824_RS08740	COG0596	Alpha beta hydrolase
CK824_RS08745	COG2271	Major facilitator Superfamily
CK824_RS08750	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CK824_RS08755	COG3485	protocatechuate 3,4-dioxygenase
CK824_RS08760	COG3485	protocatechuate 3,4-dioxygenase
CK824_RS08765	COG0710	3-dehydroquinate dehydratase activity
CK824_RS08770	COG3420	alginic acid biosynthetic process
CK824_RS08775	COG3659	wide pore channel activity
CK824_RS08780	COG4993	Dehydrogenase
CK824_RS08790	COG2391	methyltransferase activity
CK824_RS08805	COG1414	Transcriptional regulator
CK824_RS08810	COG0583	DNA-binding transcription factor activity
CK824_RS08815	COG1960	acyl-CoA dehydrogenase activity
CK824_RS08840	COG2814	Major facilitator Superfamily
CK824_RS08850	COG0154	amidase activity
CK824_RS08870	COG4638	Rieske (2fe-2S)
CK824_RS08880	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS08890	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_RS08900	COG3733	amine oxidase
CK824_RS08910	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS08920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CK824_RS08925	COG0183	Belongs to the thiolase family
CK824_RS08930	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK824_RS08935	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CK824_RS08945	COG4829	muconolactone delta-isomerase
CK824_RS08950	COG4948	Mandelate Racemase Muconate Lactonizing
CK824_RS08955	COG0583	DNA-binding transcription factor activity
CK824_RS08965	COG2186	Transcriptional regulator
CK824_RS08985	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS09005	COG1960	acyl-CoA dehydrogenase activity
CK824_RS09010	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS09015	COG3829	transcription factor binding
CK824_RS09025	COG3162	membrane
CK824_RS09040	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS09055	COG0753	catalase activity
CK824_RS09080	COG1846	Transcriptional regulator
CK824_RS09085	COG1902	pentaerythritol trinitrate reductase activity
CK824_RS09085	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_RS09095	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CK824_RS09125	COG1309	transcriptional regulator
CK824_RS09135	COG1335	isochorismatase
CK824_RS09140	COG0583	DNA-binding transcription factor activity
CK824_RS09150	COG0475	glutathione-regulated potassium exporter activity
CK824_RS09150	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK824_RS09160	COG1473	amidohydrolase
CK824_RS09175	COG2831	hemolysin activation secretion protein
CK824_RS09180	COG3210	domain, Protein
CK824_RS09210	COG2188	Transcriptional regulator
CK824_RS09225	COG0583	DNA-binding transcription factor activity
CK824_RS09255	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK824_RS09275	COG1566	PFAM secretion protein HlyD family protein
CK824_RS09290	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS09295	COG0129	dihydroxy-acid dehydratase activity
CK824_RS09305	COG0583	DNA-binding transcription factor activity
CK824_RS09310	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
CK824_RS09320	COG2084	Dehydrogenase
CK824_RS09325	COG2207	Transcriptional regulator
CK824_RS09340	COG1064	alcohol dehydrogenase
CK824_RS09350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
CK824_RS09355	COG1120	ATPase activity
CK824_RS09375	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CK824_RS09495	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
CK824_RS09550	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS09565	COG2207	Transcriptional regulator
CK824_RS09575	COG2205	protein histidine kinase activity
CK824_RS09580	COG0745	RESPONSE REGULATOR receiver
CK824_RS09585	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_RS09590	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK824_RS09595	COG1538	Outer membrane efflux protein
CK824_RS09605	COG2072	flavoprotein involved in K transport
CK824_RS09625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK824_RS09645	COG3539	Fimbrial protein
CK824_RS09675	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
CK824_RS09685	COG0753	catalase activity
CK824_RS09700	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
CK824_RS09765	COG1535	isochorismatase
CK824_RS09765	COG3433	isochorismatase activity
CK824_RS09770	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS09775	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
CK824_RS09780	COG4149	molybdate abc transporter
CK824_RS09785	COG0725	ABC transporter, periplasmic molybdate-binding protein
CK824_RS09795	COG4638	Rieske (2fe-2S)
CK824_RS09800	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CK824_RS09805	COG0543	2 iron, 2 sulfur cluster binding
CK824_RS09805	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK824_RS09830	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS09845	COG2207	Transcriptional regulator
CK824_RS09855	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS09860	COG2610	gluconate transmembrane transporter activity
CK824_RS09870	COG0583	DNA-binding transcription factor activity
CK824_RS09880	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK824_RS09885	COG2031	fatty acid transporter
CK824_RS09890	COG0183	Belongs to the thiolase family
CK824_RS09895	COG0583	DNA-binding transcription factor activity
CK824_RS09900	COG0583	DNA-binding transcription factor activity
CK824_RS09915	COG1027	Aspartate ammonia-lyase
CK824_RS09925	COG0477	Major facilitator Superfamily
CK824_RS09945	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK824_RS09950	COG4521	taurine ABC transporter
CK824_RS09965	COG2188	Transcriptional regulator
CK824_RS09975	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
CK824_RS09980	COG1733	regulation of RNA biosynthetic process
CK824_RS09985	COG3708	Transcriptional regulator
CK824_RS09985	COG2207	Transcriptional regulator
CK824_RS10000	COG0730	response to heat
CK824_RS10010	COG3453	Protein conserved in bacteria
CK824_RS10010	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK824_RS10020	COG3781	membrane
CK824_RS10025	COG1063	alcohol dehydrogenase
CK824_RS10035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CK824_RS10040	COG0508	dehydrogenase complex catalyzes the overall conversion of
CK824_RS10045	COG0022	dehydrogenase e1 component
CK824_RS10050	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
CK824_RS10055	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
CK824_RS10070	COG3706	GGDEF domain
CK824_RS10085	COG0133	tryptophan synthase activity
CK824_RS10095	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CK824_RS10130	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
CK824_RS10155	COG2226	methyltransferase
CK824_RS10210	COG0842	Transport permease protein
CK824_RS10215	COG0842	Transport permease protein
CK824_RS10220	COG1131	(ABC) transporter
CK824_RS10235	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
CK824_RS10240	COG4773	Receptor
CK824_RS10260	COG0730	response to heat
CK824_RS10265	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CK824_RS10285	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
CK824_RS10345	COG4264	IucA IucC family
CK824_RS10350	COG4264	IucA IucC family
CK824_RS10370	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CK824_RS10385	COG1960	acyl-CoA dehydrogenase activity
CK824_RS10390	COG1960	acyl-CoA dehydrogenase activity
CK824_RS10395	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
CK824_RS10400	COG2207	Transcriptional regulator
CK824_RS10405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK824_RS10410	COG0776	regulation of translation
CK824_RS10435	COG0822	iron-sulfur transferase activity
CK824_RS10440	COG0316	Belongs to the HesB IscA family
CK824_RS10470	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
CK824_RS10490	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
CK824_RS10495	COG0702	epimerase
CK824_RS10530	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CK824_RS10540	COG0339	signal peptide processing
CK824_RS10595	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
CK824_RS10600	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
CK824_RS10630	COG0776	regulation of translation
CK824_RS10695	COG0084	hydrolase, TatD family'
CK824_RS10715	COG1663	tetraacyldisaccharide 4'-kinase activity
CK824_RS10720	COG1132	(ABC) transporter
CK824_RS10730	COG0811	peptide transport
CK824_RS10735	COG1475	DNA binding
CK824_RS10740	COG1192	Involved in chromosome partitioning
CK824_RS10750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
CK824_RS10765	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
CK824_RS10770	COG0191	fructose-bisphosphate aldolase activity
CK824_RS10790	COG0424	maF-like protein
CK824_RS10795	COG2850	peptidyl-arginine hydroxylation
CK824_RS10805	COG0640	Transcriptional regulator
CK824_RS10815	COG3619	membrane
CK824_RS10820	COG3122	Protein conserved in bacteria
CK824_RS10825	COG1132	(ABC) transporter
CK824_RS10865	COG0477	Major facilitator Superfamily
CK824_RS10890	COG1271	oxidase subunit
CK824_RS10895	COG1294	oxidase, subunit
CK824_RS10905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_RS10925	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
CK824_RS10945	COG3052	prosthetic group binding
CK824_RS10950	COG1767	triphosphoribosyl-dephospho-CoA synthase activity
CK824_RS10960	COG2814	Major facilitator Superfamily
CK824_RS10980	COG1346	cytolysis
CK824_RS10990	COG0583	DNA-binding transcription factor activity
CK824_RS10995	COG0625	glutathione transferase activity
CK824_RS11000	COG0625	glutathione transferase activity
CK824_RS11005	COG0583	DNA-binding transcription factor activity
CK824_RS11020	COG1045	serine acetyltransferase
CK824_RS11025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CK824_RS11030	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CK824_RS11040	COG1280	lysine exporter protein (LysE YggA)
CK824_RS11055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK824_RS11060	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CK824_RS11065	COG1126	abc transporter atp-binding protein
CK824_RS11070	COG0765	amino acid transport
CK824_RS11075	COG0765	amino acid transport
CK824_RS11095	COG2205	protein histidine kinase activity
CK824_RS11095	COG0784	Response regulator, receiver
CK824_RS11115	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
CK824_RS11135	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS11180	COG0583	DNA-binding transcription factor activity
CK824_RS11200	COG0318	PFAM AMP-dependent synthetase and ligase
CK824_RS11205	COG1309	transcriptional regulator
CK824_RS11210	COG1960	acyl-CoA dehydrogenase activity
CK824_RS11215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CK824_RS11220	COG1024	Enoyl-CoA hydratase
CK824_RS11225	COG4770	biotin carboxylase activity
CK824_RS11235	COG0583	DNA-binding transcription factor activity
CK824_RS11250	COG1960	acyl-CoA dehydrogenase activity
CK824_RS11260	COG2814	Major facilitator Superfamily
CK824_RS11270	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
CK824_RS11275	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
CK824_RS11280	COG2814	Major facilitator Superfamily
CK824_RS11285	COG1960	acyl-CoA dehydrogenase activity
CK824_RS11290	COG1024	Enoyl-CoA hydratase
CK824_RS11295	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS11300	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK824_RS11305	COG0183	Belongs to the thiolase family
CK824_RS11315	COG2814	Major facilitator Superfamily
CK824_RS11325	COG1024	Enoyl-CoA hydratase
CK824_RS11340	COG1960	acyl-CoA dehydrogenase activity
CK824_RS11345	COG2814	Major facilitator Superfamily
CK824_RS11350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CK824_RS11355	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
CK824_RS11370	COG3842	ATPase activity
CK824_RS11375	COG1840	ABC-type Fe3 transport system, periplasmic component
CK824_RS11385	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_RS11390	COG1414	Transcriptional regulator
CK824_RS11400	COG0583	DNA-binding transcription factor activity
CK824_RS11405	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
CK824_RS11410	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS11420	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
CK824_RS11430	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS11435	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK824_RS11440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_RS11445	COG2267	carboxylic ester hydrolase activity
CK824_RS11465	COG3038	cytochrome b561
CK824_RS11470	COG0753	catalase activity
CK824_RS11510	COG2050	protein possibly involved in aromatic compounds catabolism
CK824_RS11520	COG3327	negative regulation of DNA-templated transcription, initiation
CK824_RS11525	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
CK824_RS11530	COG0183	Belongs to the thiolase family
CK824_RS11535	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK824_RS11540	COG1024	Enoyl-CoA hydratase
CK824_RS11545	COG1024	Enoyl-CoA hydratase
CK824_RS11550	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
CK824_RS11555	COG2151	metal-sulfur cluster biosynthetic enzyme
CK824_RS11560	COG3396	Phenylacetate-CoA oxygenase
CK824_RS11565	COG3460	Phenylacetate-CoA oxygenase
CK824_RS11570	COG3396	Phenylacetate-CoA oxygenase
CK824_RS11575	COG2030	dehydratase
CK824_RS11575	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS11580	COG1760	l-serine dehydratase
CK824_RS11585	COG0531	amino acid
CK824_RS11590	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS11605	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_RS11615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
CK824_RS11635	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK824_RS11650	COG0789	Transcriptional regulator
CK824_RS11665	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
CK824_RS11680	COG2807	transmembrane transport
CK824_RS11685	COG0590	tRNA wobble adenosine to inosine editing
CK824_RS11705	COG0864	Transcriptional regulator
CK824_RS11725	COG2249	NAD(P)H dehydrogenase (quinone) activity
CK824_RS11730	COG0439	Biotin carboxylase
CK824_RS11745	COG1063	alcohol dehydrogenase
CK824_RS11755	COG1309	transcriptional regulator
CK824_RS11780	COG0038	chloride channel
CK824_RS11785	COG4770	biotin carboxylase activity
CK824_RS11805	COG1914	H( )-stimulated, divalent metal cation uptake system
CK824_RS11810	COG0583	DNA-binding transcription factor activity
CK824_RS11865	COG1250	3-hydroxyacyl-CoA dehydrogenase
CK824_RS11885	COG2814	Major facilitator Superfamily
CK824_RS11900	COG1560	Kdo2-lipid A biosynthetic process
CK824_RS11910	COG5006	permease, DMT superfamily
CK824_RS11915	COG1522	sequence-specific DNA binding
CK824_RS11930	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CK824_RS11940	COG4122	O-methyltransferase activity
CK824_RS11970	COG1538	Outer membrane efflux protein
CK824_RS11975	COG1137	ATPase activity
CK824_RS11980	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
CK824_RS11990	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
CK824_RS11995	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
CK824_RS11995	COG0517	IMP dehydrogenase activity
CK824_RS12035	COG2814	Major facilitator Superfamily
CK824_RS12075	COG1278	Cold shock
CK824_RS12080	COG1280	lysine exporter protein (LysE YggA)
CK824_RS12115	COG1570	exodeoxyribonuclease VII activity
CK824_RS12170	COG0583	DNA-binding transcription factor activity
CK824_RS12175	COG4638	Rieske (2fe-2S)
CK824_RS12180	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
CK824_RS12185	COG0633	Ferredoxin
CK824_RS12185	COG0543	2 iron, 2 sulfur cluster binding
CK824_RS12190	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS12195	COG3135	benzoate transporter
CK824_RS12200	COG2814	Major facilitator Superfamily
CK824_RS12215	COG1643	Atp-dependent helicase
CK824_RS12220	COG0450	alkyl hydroperoxide reductase
CK824_RS12230	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
CK824_RS12240	COG3634	alkyl hydroperoxide reductase activity
CK824_RS12260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
CK824_RS12265	COG0625	glutathione transferase activity
CK824_RS12275	COG2885	chlorophyll binding
CK824_RS12310	COG0542	response to heat
CK824_RS12325	COG1765	OsmC-like protein
CK824_RS12335	COG0667	Aldo Keto reductase
CK824_RS12350	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
CK824_RS12360	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
CK824_RS12370	COG0527	aspartate kinase activity
CK824_RS12380	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CK824_RS12390	COG3038	cytochrome b561
CK824_RS12395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CK824_RS12400	COG2252	PERMEase
CK824_RS12410	COG2072	flavoprotein involved in K transport
CK824_RS12450	COG0531	amino acid
CK824_RS12460	COG1113	amino acid transport
CK824_RS12505	COG3209	COG3209 Rhs family protein
CK824_RS12530	COG4269	membrane
CK824_RS12545	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_RS12545	COG1902	pentaerythritol trinitrate reductase activity
CK824_RS12555	COG2203	Gaf domain
CK824_RS12555	COG3706	GGDEF domain
CK824_RS12555	COG5001	Diguanylate cyclase
CK824_RS12555	COG4251	negative regulation of phosphorylation
CK824_RS12565	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK824_RS12585	COG4172	Belongs to the ABC transporter superfamily
CK824_RS12590	COG4239	(ABC) transporter, permease
CK824_RS12595	COG4174	ABC transporter (Permease)
CK824_RS12605	COG1388	LysM domain
CK824_RS12605	COG1388	LysM domain
CK824_RS12605	COG0741	lytic transglycosylase activity
CK824_RS12605	COG0741	lytic transglycosylase activity
CK824_RS12610	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK824_RS12650	COG0583	DNA-binding transcription factor activity
CK824_RS12655	COG1279	arginine transmembrane transporter activity
CK824_RS12675	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_RS12680	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_RS12685	COG0006	proline dipeptidase activity
CK824_RS12720	COG2194	sulfuric ester hydrolase activity
CK824_RS12895	COG5410	chromosome segregation
CK824_RS13070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CK824_RS13095	COG3384	dioxygenase
CK824_RS13105	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CK824_RS13110	COG2878	Part of a membrane complex involved in electron transport
CK824_RS13115	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
CK824_RS13140	COG0768	penicillin binding
CK824_RS13145	COG0742	ribosomal rna small subunit methyltransferase
CK824_RS13160	COG0830	nickel cation binding
CK824_RS13170	COG0804	urea catabolic process
CK824_RS13210	COG1253	flavin adenine dinucleotide binding
CK824_RS13220	COG2851	Citrate transporter
CK824_RS13270	COG1773	rubredoxin
CK824_RS13275	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
CK824_RS13285	COG0583	DNA-binding transcription factor activity
CK824_RS13310	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
CK824_RS13315	COG4181	ATPase activity
CK824_RS13360	COG1262	PFAM Formylglycine-generating sulfatase enzyme
CK824_RS13380	COG0306	phosphate transporter
CK824_RS13390	COG3958	Transketolase
CK824_RS13395	COG3959	Transketolase, thiamine diphosphate binding domain
CK824_RS13400	COG2271	Major facilitator Superfamily
CK824_RS13405	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS13410	COG0583	DNA-binding transcription factor activity
CK824_RS13430	COG2223	nitrite transmembrane transporter activity
CK824_RS13435	COG2207	Transcriptional regulator
CK824_RS13440	COG2066	Belongs to the glutaminase family
CK824_RS13445	COG0242	peptide deformylase activity
CK824_RS13450	COG0477	Major facilitator Superfamily
CK824_RS13460	COG0028	Belongs to the TPP enzyme family
CK824_RS13475	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS13480	COG2267	carboxylic ester hydrolase activity
CK824_RS13490	COG2271	Major facilitator Superfamily
CK824_RS13495	COG0446	pyridine nucleotide-disulphide oxidoreductase
CK824_RS13505	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS13525	COG1414	Transcriptional regulator
CK824_RS13540	COG1024	Enoyl-CoA hydratase
CK824_RS13550	COG1215	transferase activity, transferring glycosyl groups
CK824_RS13555	COG0726	polysaccharide deacetylase
CK824_RS13555	COG1649	PFAM Uncharacterised BCR, COG1649
CK824_RS13565	COG4681	YaeQ
CK824_RS13575	COG0523	cobalamin synthesis protein
CK824_RS13585	COG1607	acyl-coa hydrolase
CK824_RS13595	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_RS13600	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
CK824_RS13605	COG1309	transcriptional regulator
CK824_RS13630	COG2040	homocysteine
CK824_RS13635	COG0531	amino acid
CK824_RS13660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK824_RS13665	COG0477	Major facilitator Superfamily
CK824_RS13735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK824_RS13820	COG0592	DNA-directed DNA polymerase activity
CK824_RS13860	COG2026	Addiction module toxin, RelE StbE family
CK824_RS14010	COG3755	Protein conserved in bacteria
CK824_RS14055	COG1484	DNA-dependent DNA replication
CK824_RS14170	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
CK824_RS14200	COG0405	Gamma-glutamyltransferase
CK824_RS14205	COG2814	Major facilitator Superfamily
CK824_RS14215	COG2050	protein possibly involved in aromatic compounds catabolism
CK824_RS14230	COG1090	epimerase
CK824_RS14250	COG0420	3'-5' exonuclease activity
CK824_RS14275	COG0735	belongs to the Fur family
CK824_RS14280	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
CK824_RS14305	COG0121	glutamine amidotransferase
CK824_RS14320	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK824_RS14330	COG0210	DNA helicase
CK824_RS14335	COG2885	chlorophyll binding
CK824_RS14340	COG0204	Acyl-transferase
CK824_RS14355	COG2894	cell division
CK824_RS14380	COG1280	lysine exporter protein (LysE YggA)
CK824_RS14385	COG1674	ftsk spoiiie
CK824_RS14385	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
CK824_RS14390	COG0492	ferredoxin-NADP+ reductase activity
CK824_RS14395	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
CK824_RS14405	COG0456	acetyltransferase
CK824_RS14450	COG1981	membrane
CK824_RS14465	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
CK824_RS14465	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK824_RS14485	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS14495	COG0657	acetylesterase activity
CK824_RS14505	COG0473	3-isopropylmalate dehydrogenase activity
CK824_RS14510	COG0583	DNA-binding transcription factor activity
CK824_RS14530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
CK824_RS14555	COG0564	pseudouridine synthase activity
CK824_RS14565	COG0358	DNA primase activity
CK824_RS14580	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
CK824_RS14610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
CK824_RS14640	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
CK824_RS14650	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CK824_RS14650	COG0351	phosphomethylpyrimidine kinase
CK824_RS14650	COG0352	thiamine-phosphate diphosphorylase activity
CK824_RS14655	COG1652	LysM domain
CK824_RS14680	COG1399	metal-binding, possibly nucleic acid-binding protein
CK824_RS14685	COG3101	peptidyl-lysine hydroxylation
CK824_RS14690	COG0009	L-threonylcarbamoyladenylate synthase
CK824_RS14695	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CK824_RS14700	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CK824_RS14715	COG4106	trans-aconitate 2-methyltransferase activity
CK824_RS14730	COG2226	methyltransferase
CK824_RS14730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CK824_RS14730	COG0596	Alpha beta hydrolase
CK824_RS14735	COG1877	trehalose-phosphatase activity
CK824_RS14740	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
CK824_RS14745	COG2223	nitrite transmembrane transporter activity
CK824_RS14765	COG1196	nuclear chromosome segregation
CK824_RS14775	COG0730	response to heat
CK824_RS14790	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
CK824_RS14800	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK824_RS14860	COG0489	protein tyrosine kinase activity
CK824_RS14870	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK824_RS14870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK824_RS14900	COG2515	1-aminocyclopropane-1-carboxylate deaminase
CK824_RS14905	COG2081	HI0933 family
CK824_RS14915	COG0668	transmembrane transport
CK824_RS14935	COG0583	DNA-binding transcription factor activity
CK824_RS14955	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
CK824_RS14960	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CK824_RS14990	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
CK824_RS15030	COG0745	RESPONSE REGULATOR receiver
CK824_RS15050	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CK824_RS15060	COG2205	protein histidine kinase activity
CK824_RS15130	COG4993	Dehydrogenase
CK824_RS15150	COG0384	phenazine biosynthesis protein PhzF
CK824_RS15180	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
CK824_RS15195	COG0583	DNA-binding transcription factor activity
CK824_RS15225	COG0583	DNA-binding transcription factor activity
CK824_RS15245	COG0583	DNA-binding transcription factor activity
CK824_RS15250	COG1053	succinate dehydrogenase
CK824_RS15260	COG1804	L-carnitine dehydratase bile acid-inducible protein F
CK824_RS15265	COG2814	Major facilitator Superfamily
CK824_RS15270	COG1960	acyl-CoA dehydrogenase activity
CK824_RS15275	COG0583	DNA-binding transcription factor activity
CK824_RS15280	COG1063	alcohol dehydrogenase
CK824_RS15310	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CK824_RS15315	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
CK824_RS15320	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK824_RS15335	COG3667	copper resistance
CK824_RS15340	COG2132	Multicopper oxidase
CK824_RS15350	COG0561	phosphatase activity
CK824_RS15355	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CK824_RS15380	COG1214	PFAM Peptidase M22, glycoprotease
CK824_RS15430	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
CK824_RS15440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
CK824_RS15445	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
CK824_RS15450	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CK824_RS15510	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CK824_RS15520	COG1846	Transcriptional regulator
CK824_RS15525	COG1764	response to oxidative stress
CK824_RS15575	COG0037	tRNA processing
CK824_RS15585	COG0248	Ppx GppA phosphatase
CK824_RS15615	COG0072	phenylalanine-tRNA ligase activity
CK824_RS15655	COG1238	metal cluster binding
CK824_RS15660	COG0625	glutathione transferase activity
CK824_RS15680	COG0318	PFAM AMP-dependent synthetase and ligase
CK824_RS15685	COG3028	Belongs to the UPF0307 family
CK824_RS15690	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
CK824_RS15710	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CK824_RS15715	COG0617	tRNA 3'-terminal CCA addition
CK824_RS15720	COG1555	photosystem II stabilization
CK824_RS15725	COG3956	TIGRFAM MazG family protein
CK824_RS15735	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CK824_RS15755	COG0784	Response regulator, receiver
CK824_RS15755	COG2205	protein histidine kinase activity
CK824_RS15755	COG5002	protein histidine kinase activity
CK824_RS15760	COG1024	Enoyl-CoA hydratase
CK824_RS15765	COG2084	Dehydrogenase
CK824_RS15770	COG3622	Belongs to the hyi family
CK824_RS15800	COG0697	spore germination
CK824_RS15810	COG2814	Major facilitator Superfamily
CK824_RS15815	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
CK824_RS15825	COG0583	DNA-binding transcription factor activity
CK824_RS15835	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
CK824_RS15850	COG0084	hydrolase, TatD family'
CK824_RS15865	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
CK824_RS15900	COG0440	acetolactate synthase activity
CK824_RS15905	COG0028	Belongs to the TPP enzyme family
CK824_RS15930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
CK824_RS15935	COG1136	(ABC) transporter
CK824_RS15935	COG0577	efflux transmembrane transporter activity
CK824_RS15940	COG1538	Outer membrane efflux protein
CK824_RS15955	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
CK824_RS15960	COG1162	GTPase activity
CK824_RS15970	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
CK824_RS15990	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
CK824_RS15995	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS16035	COG2986	histidine ammonia-lyase
CK824_RS16050	COG0318	PFAM AMP-dependent synthetase and ligase
CK824_RS16060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK824_RS16105	COG1426	Protein conserved in bacteria
CK824_RS16140	COG0793	Belongs to the peptidase S41A family
CK824_RS16155	COG2267	carboxylic ester hydrolase activity
CK824_RS16165	COG1012	belongs to the aldehyde dehydrogenase family
CK824_RS16170	COG3265	gluconokinase activity
CK824_RS16180	COG0800	Aldolase
CK824_RS16190	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CK824_RS16195	COG0857	belongs to the CobB CobQ family
CK824_RS16195	COG0280	phosphate acetyltransferase
CK824_RS16200	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
CK824_RS16200	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
CK824_RS16220	COG0740	serine-type endopeptidase activity
CK824_RS16230	COG4774	siderophore transport
CK824_RS16240	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
CK824_RS16250	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
CK824_RS16250	COG2813	Specifically methylates the guanine in position
CK824_RS16350	COG0788	formyltetrahydrofolate deformylase activity
CK824_RS16375	COG4651	solute:proton antiporter activity
CK824_RS16375	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK824_RS16395	COG0724	RNA recognition motif
CK824_RS16400	COG0210	DNA helicase
CK824_RS16425	COG1733	regulation of RNA biosynthetic process
CK824_RS16435	COG2900	Belongs to the SlyX family
CK824_RS16440	COG0488	(ABC) transporter
CK824_RS16445	COG1280	lysine exporter protein (LysE YggA)
CK824_RS16450	COG1560	Kdo2-lipid A biosynthetic process
CK824_RS16460	COG1301	dicarboxylic acid transport
CK824_RS16515	COG0473	3-isopropylmalate dehydrogenase activity
CK824_RS16580	COG0583	DNA-binding transcription factor activity
CK824_RS16590	COG0625	glutathione transferase activity
CK824_RS16595	COG2378	regulation of single-species biofilm formation
CK824_RS16600	COG0546	phosphoglycolate phosphatase activity
CK824_RS16615	COG1530	ribonuclease E activity
CK824_RS16620	COG0318	PFAM AMP-dependent synthetase and ligase
CK824_RS16635	COG0583	DNA-binding transcription factor activity
CK824_RS16640	COG4221	oxidoreductase activity
CK824_RS16645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
CK824_RS16655	COG0534	Mate efflux family protein
CK824_RS16670	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
CK824_RS16710	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
CK824_RS16715	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
CK824_RS16730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
CK824_RS16740	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
CK824_RS16740	COG0644	oxidoreductase
CK824_RS16745	COG0425	Belongs to the sulfur carrier protein TusA family
CK824_RS16750	COG4535	Mg2 and Co2 transporter CorC
CK824_RS16760	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
CK824_RS16780	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CK824_RS16785	COG0475	glutathione-regulated potassium exporter activity
CK824_RS16785	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CK824_RS16790	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
CK824_RS16800	COG0484	heat shock protein binding
CK824_RS16805	COG0789	Transcriptional regulator
CK824_RS16810	COG0598	Magnesium transport protein CorA
CK824_RS16825	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
CK824_RS16830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CK824_RS16835	COG1074	ATP-dependent DNA helicase activity
CK824_RS16840	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
CK824_RS16860	COG2226	methyltransferase
CK824_RS16875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
CK824_RS16880	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
CK824_RS16895	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
CK824_RS16895	COG2111	Na H antiporter
CK824_RS16900	COG1006	Multisubunit Na H antiporter MnhC subunit
CK824_RS16905	COG0651	ATP synthesis coupled electron transport
CK824_RS16910	COG1863	multisubunit Na H antiporter MnhE subunit
CK824_RS16915	COG2212	antiporter activity
CK824_RS16920	COG1320	monovalent cation:proton antiporter activity
CK824_RS16935	COG0195	Participates in both transcription termination and antitermination
CK824_RS16985	COG0237	dephospho-CoA kinase activity
CK824_RS16995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CK824_RS17010	COG0497	DNA recombination
CK824_RS17020	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
CK824_RS17050	COG2169	Transcriptional regulator
CK824_RS17050	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CK824_RS17055	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CK824_RS17125	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
CK824_RS17140	COG0326	Molecular chaperone. Has ATPase activity
CK824_RS17155	COG2056	Na+-H+ antiporter family
CK824_RS17160	COG0596	Alpha beta hydrolase
CK824_RS17255	COG0546	phosphoglycolate phosphatase activity
CK824_RS17260	COG1716	ATPase activity
CK824_RS17305	COG0181	hydroxymethylbilane synthase activity
CK824_RS17315	COG3275	phosphorelay sensor kinase activity
CK824_RS17335	COG1538	Outer membrane efflux protein
CK824_RS17340	COG0697	spore germination
CK824_RS17365	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
CK824_RS17370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
CK824_RS17375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
CK824_RS17380	COG0772	Belongs to the SEDS family
CK824_RS17405	COG4974	Belongs to the 'phage' integrase family
CK824_RS17410	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK824_RS17420	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
CK824_RS17430	COG2197	response regulator
CK824_RS17445	COG0793	Belongs to the peptidase S41A family
CK824_RS17450	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
CK824_RS17455	COG0795	lipopolysaccharide-transporting ATPase activity
CK824_RS17495	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK824_RS17495	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
CK824_RS17505	COG0004	ammonium transporteR
CK824_RS17510	COG0347	Belongs to the P(II) protein family
CK824_RS17520	COG0606	chelatase, subunit chli
CK824_RS17575	COG0659	secondary active sulfate transmembrane transporter activity
CK824_RS17580	COG0589	response to stress
CK824_RS17610	COG0606	chelatase, subunit chli
CK824_RS17615	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CK824_RS17625	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CK824_RS17640	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CK824_RS17655	COG0318	PFAM AMP-dependent synthetase and ligase
CK824_RS17665	COG0477	Major facilitator Superfamily
CK824_RS17670	COG2860	membrane
CK824_RS17680	COG1253	flavin adenine dinucleotide binding
CK824_RS17700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CK824_RS17735	COG0655	NAD(P)H dehydrogenase (quinone) activity
CK824_RS17745	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
CK824_RS17780	COG1309	transcriptional regulator
CK824_RS17815	COG0758	DNA mediated transformation
CK824_RS17825	COG0697	spore germination
CK824_RS17830	COG1309	transcriptional regulator
CK824_RS17845	COG0386	Belongs to the glutathione peroxidase family
CK824_RS17910	COG1121	(ABC) transporter
CK824_RS17915	COG1108	ABC-type Mn2 Zn2 transport systems permease components
CK824_RS17920	COG1280	lysine exporter protein (LysE YggA)
CK824_RS17925	COG2837	iron assimilation
CK824_RS17935	COG0281	malic enzyme
CK824_RS17980	COG0519	Catalyzes the synthesis of GMP from XMP
CK824_RS17980	COG0518	GMP synthase (glutamine-hydrolyzing) activity
CK824_RS17985	COG4399	Belongs to the UPF0754 family
CK824_RS17990	COG2259	Doxx family
CK824_RS17995	COG0586	Pfam SNARE associated Golgi protein
CK824_RS18010	COG1192	Involved in chromosome partitioning
CK824_RS18020	COG0271	Belongs to the BolA IbaG family
CK824_RS18040	COG2267	carboxylic ester hydrolase activity
CK824_RS18060	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
CK824_RS18060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
CK824_RS18060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
CK824_RS18060	COG3321	synthase
CK824_RS18065	COG1960	acyl-CoA dehydrogenase activity
CK824_RS18075	COG2197	response regulator
CK824_RS18085	COG3916	Acyl-homoserine-lactone synthase
CK824_RS18090	COG0477	Major facilitator Superfamily
CK824_RS18095	COG1024	Enoyl-CoA hydratase
CK824_RS18100	COG1024	Enoyl-CoA hydratase
CK824_RS18105	COG1960	acyl-CoA dehydrogenase activity
CK824_RS18110	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
CK824_RS18130	COG1113	amino acid transport
CK824_RS18135	COG1113	amino acid transport
CK824_RS18140	COG0251	oxidation-reduction process
CK824_RS18180	COG0564	pseudouridine synthase activity
CK824_RS18245	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CK824_RS18260	COG1802	Transcriptional regulator
CK824_RS18270	COG1448	Aminotransferase
CK824_RS18275	COG0277	FAD linked oxidase domain protein
CK824_RS18285	COG2186	Transcriptional regulator
CK824_RS18295	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
CK824_RS18300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CK824_RS18315	COG1210	Utp--glucose-1-phosphate uridylyltransferase
CK824_RS18325	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
CK824_RS18335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CK824_RS18340	COG0438	transferase activity, transferring glycosyl groups
CK824_RS18360	COG1216	Glycosyl transferase, family 2
CK824_RS18365	COG5039	Polysaccharide pyruvyl transferase
CK824_RS18375	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
CK824_RS18380	COG1596	polysaccharide export
CK824_RS18405	COG0728	peptidoglycan biosynthetic process
CK824_RS18410	COG3023	N-Acetylmuramoyl-L-alanine amidase
CK824_RS18465	COG0546	phosphoglycolate phosphatase activity
CK824_RS18470	COG1028	Short-chain dehydrogenase reductase Sdr
CK824_RS18490	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK824_RS18495	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
CK824_RS18500	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
CK824_RS18505	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CK824_RS18510	COG1116	anion transmembrane transporter activity
CK824_RS18515	COG1309	transcriptional regulator
CK824_RS18520	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
CK824_RS18530	COG0196	riboflavin kinase activity
CK824_RS18535	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
CK824_RS18545	COG1047	Peptidyl-prolyl cis-trans
CK824_RS18585	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CK824_RS18590	COG0657	acetylesterase activity
CK824_RS18640	COG2951	lytic endotransglycosylase activity
CK824_RS18645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CK824_RS18665	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
CK824_RS18675	COG0671	phosphoesterase, PA-phosphatase related
CK824_RS18680	COG0861	Integral membrane protein TerC family
CK824_RS18690	COG0754	glutathionylspermidine amidase activity
CK824_RS18700	COG0402	S-adenosylhomocysteine deaminase activity
CK824_RS18715	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
CK824_RS18720	COG1230	cation diffusion facilitator family transporter
CK824_RS18735	COG0706	membrane insertase activity